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MIYAMATO Atushi  宮本 敦史

ORCIDConnect your ORCID iD *help
Researcher Number 00362731
Affiliation (based on the past Project Information) *help 2008: 大阪医療センター, 臨床研究部, 医師
2008: 大阪大学, 医学系・研究科, 助教
2007: 国立病院機構大阪医療センター, 外科, 医師
2004 – 2006: 大阪大学, 医学系研究科, 助手
Review Section/Research Field
Except Principal Investigator
Digestive surgery / General surgery
Keywords
Except Principal Investigator
IFN-α / IFN受容体 / 化学療法 / 血管新生 / インターフェロン / 門脈内腫瘍栓 / 肝細胞癌 / DNA microarray analysis / novel molecular markers of human hepatocellular carcinoma / 網羅的遺伝子発現解析 … More / 新規肝細胞癌腫瘍マーカー / angiogenesis / IFN-receptor / chemotherapy / Gene Expression Profiling / portal venous thrombus / intractable and advanced cancer / hepatocellular carcinoma / Fas-L / Fas / NK細胞 / TRAIL受容体 / TRAIL / IFN併用化学療法 / 網羅的遺伝子解析 / 難治性進行癌 / 拒絶反応 / 蛋白解析 / 胆汁 / 急性拒絶反応 / 免疫抑制 / グラフト肝障害 / 肝移植 / Fas-FasL系 / 免疫腑活作用 / 抗腫瘍効果 / 5-FU / トランスクリプトーム解析 / 化学療法IFN受容体 / 進行癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (8 People)
  •  Development of potential new treatment for theHCC targeting specificsignal and molecules

    • Principal Investigator
      NAGANO Hiroaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  Diagnostic system for acute cellular rejection in livertransplantation using protemomic analysis of bile

    • Principal Investigator
      MARUHASHI Shigeru
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Identifying novel molecular markers of human hepatocellular carcinoma

    • Principal Investigator
      TAKEDA Yutaka
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  The establishment of novel multimodal treatment through the hepatoma specific siginaling pathway for the intractable and advanced hepatocellular carcinoma

    • Principal Investigator
      NAGANO Hiroaki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University

All 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] 肝細胞癌根治切除後10年無再発生存例の臨床病理学的因子に関する検討2008

    • Author(s)
      野田剛広、永野浩昭、丸橋繁、小林省吾、宮本敦史、武田裕、村上昌裕、堂野恵三、梅下浩司、若狭研一、門田守人
    • Journal Title

      Liver Cancer 14(1)

      Pages: 43-47

    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Pilot study of combination chemotherapy of S-1, a novel oral DPD inhibitor, and interferon-α for advanced hepatocellular carcinoma with extrahepatic metastasis2008

    • Author(s)
      Nakamura M.,Nagano H., Marubashi H., Miyamoto A., Takeda Y., Kobayashi S., Wada H., Noda T., Dono K ., Umeshita K., Monden M.
    • Journal Title

      Cancer有 112(8)

      Pages: 1766-1771

    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Pilot study of combination chemotherapy of S-l, a novel oral DPD inhibitor, and interferon-a for advanced hepatocellular carcinoma withextrahepatic metastasis2008

    • Author(s)
      Nakamura M., Nagano H., Marubashi H., Miyamoto A., Takeda Y., Kobayashi S., Wada H., Noda T., Dono K ., Umeshita K., Monden M.
    • Journal Title

      Cancer 112(8)

      Pages: 1766-1771

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] 肝細胞癌の経皮的治療後の腹腔内および穿刺経路播種に対する外科的切除の有効性2007

    • Author(s)
      野田剛広、永野浩昭、村上昌裕、小林省吾、丸橋繁、宮本敦史、武田裕、堂野恵三、梅下浩司、若狭研一、門田守人
    • Journal Title

      癌と化学療法 34(12)

      Pages: 2080-2083

    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Hepatic resection followed by IFN-α and 5-FU for advanced hepatocellular carcinoma with tumor thrombus in the major portal branch.2007

    • Author(s)
      Nagano H, Sakon M, Eguchi H, Kondo M, Yamamoto T, Ota H, Nakamura M, Wada H, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Dono K, Umeshita K, Nakamori S, Monden M
    • Journal Title

      Hepatogastroenterology 54(73)

      Pages: 172-179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Role of the Fas/FasL pathway in combination therapy with interferon-alpha and fluorouracil against hepatocellular carcinoma in vitro.2007

    • Author(s)
      Nakamura M, Nagano H, Sakon M, Yamamoto T, Ota H, Wada H, Damdinsuren B, Noda T, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Nakamori S, Dono K, Monden M.
    • Journal Title

      J Hepatol. 46(1)

      Pages: 77-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Patterns and clinicopathologic features of extrahepatic recurrence of hepatocellular carcinoma after curative resection.2007

    • Author(s)
      Yang Y, Nagano H, Ota H, Morimoto O, Nakamura M, Wada H, Noda T, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Dono K, Umeshita K, Nakamori S, Wakasa K, Sakon M, Monden M
    • Journal Title

      Surgery. 141(2)

      Pages: 196-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Complete remission of hepatocellular carcinoma with portal vein tumor thrombus and lymph node metastases by arterial infusion of 5-fluorouracil and interferon-alpha combination therapy following hepatic resection.2007

    • Author(s)
      Wada H, Nagano H, Noda T, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Dono K, Sakon M, Wakasa K, Monden M.
    • Journal Title

      J Gastroenterol 42(6)

      Pages: 501-506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Interferon alpha receptors are important for antiproliferative effect of interferon-alpha against human hepatocellular carcinoma cells.2007

    • Author(s)
      Damdinsuren B, Nagano H, Wada H, Noda T, Natsag J, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Doki Y, Dono K, Monden M.
    • Journal Title

      Hepatol Res 37(1)

      Pages: 77-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Doxorubicin/IFN-β併用化学療法と肝切除術により長期生存し得た右心房内腫瘍栓を伴う進行肝細胞癌の1例2007

    • Author(s)
      村上昌裕、永野浩昭、野田剛広、和田浩志、小林省吾、丸橋繁、宮本敦史、武田裕、堂野恵三、梅下浩司、門田守人
    • Journal Title

      癌と化学療法 34(12)

      Pages: 2087-2089

    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Interferon-a and 5-fluorouracil combination therapy following palliative hepaticresection in patients with advanced hepatocellular carcinoma, portal venous tumorthrombus in the major trunk and multiple nodules.2007

    • Author(s)
      Nagano H, Miyamoto A, Wada H, Ota H, Marubashi S, Takeda Y, Dono K, Umeshita K, Sakon M, Monden M.
    • Journal Title

      Cancer 110(11)

      Pages: 2493-2501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] Combination therapy of interferon-alpha and 5-fluorouracil inhibits tumor angiogenesisin human hepatocellular carcinoma cells by regulating vascular endothelial growth factor and angiopoietins.2007

    • Author(s)
      Wada H, Nagano H, Yamamoto H, Arail, Ota H, Nakamura M, Damdinsuren B, Noda T, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Doki Y, Dono K, Nakamori S, Sakon M, Monden M.
    • Journal Title

      Oncol Rep 18(4)

      Pages: 801-809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Journal Article] A case of hepatocellular carcinoma with multiple lung, spleen, and remnant liver metastasis successfully treated by combination chmotherapy with the novel oral DPD- inhibiting chemotherapeutic drug S-1 and interferon-α.2006

    • Author(s)
      Nakamura M., Nagano H., Wada H., Noda T., Ota H., Damdinsuren B., Marubashi S., Miyamoto A., Takeda Y., Umeshita k., Dono K., Monden M.
    • Journal Title

      J Gastroenterol 10(1007)

      Pages: 1120-1125

    • Data Source
      KAKENHI-PROJECT-17591397
  • [Journal Article] Vitamin K2 has growth inhibition effect against hepatocellular carcinoma cell lines but does not enhance anti-tumor effect of combination treatment of interferon-alpha and fluorouracil in vitro.2006

    • Author(s)
      Nakamura M, Nagano H, Noda T, Wada H, Ota H, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Doki Y, Umeshita K, Dono K, Sakon M, Monden M.
    • Journal Title

      Hepatology Research 35

      Pages: 289-295

    • Data Source
      KAKENHI-PROJECT-17591397
  • [Journal Article] Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma : importance of angiopoietin-2 and hypoxia-induced factor-1 alpha.2006

    • Author(s)
      Wada H., Nagano H., Yamamoto H., Yang Y., Kondo M., Ota H., Nakamura M., Yoshioka S., Kato H., Damdinsuren B., Tang D., Marubashi S., Miyamoto A., Takeda Y., Umeshita K., Nakamori S., Sakon M., Dono K., Wakasa K., Monden M.
    • Journal Title

      Liver International 26

      Pages: 414-423

    • Data Source
      KAKENHI-PROJECT-17591397
  • [Journal Article] TGF-beta1-induced cell growth arrest and partial differentiation is related to suppression of Id1 in some human hepatoma cells.2006

    • Author(s)
      Damdinsuren B, Nagano H, Kondo M, Natsag J, Hanada H, Nakamura M.Wada H, Kato H, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Dono K, Monden M.
    • Journal Title

      Oncology Reports 15(2)

      Pages: 401-408

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Clinical and pathological features of Allen's type C classification of resected combined hepatocellular and cholangiocarcinoma : a comparative study with hepatocellular carcinoma and cholangiocellular carcinom.2006

    • Author(s)
      Tang D., Nagano H., Nakamura M., Wada H., Marubashi S., Miyamoto A., Takeda Y., Umeshita K., Dono K., Monden M.
    • Journal Title

      J Gastronitest Surg 2006 10(7)

      Pages: 987-998

    • Data Source
      KAKENHI-PROJECT-17591397
  • [Journal Article] Angiogenesis in cholangiocellular carcinoma : Expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospodin-1 and clinicopathological significance.2006

    • Author(s)
      Tang D, Nagano H, Yamamoto H, Wada H, Nakamura M, Kondo M, Ota H, Yoshioka S, Kato H, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Dono K, Wakasa K. Monden M.
    • Journal Title

      Oncology Reports 15

      Pages: 525-532

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] TGF-betal-induced cell growth arrest and partial differentiation is related to the suppression of Id1 in human hepatoma cells.2006

    • Author(s)
      Damdinsuren B., Nagano H., Kondo M., Natsag J., Hanada H., Nakamura M., Wada H., Kato H., Marubashi S., Miyamoto A., Takeda Y., Umeshita K., Dono K., Monden M.
    • Journal Title

      Oncol Rep 15(2)

      Pages: 401-408

    • Data Source
      KAKENHI-PROJECT-17591397
  • [Journal Article] Expression of ID proteins in human hepatocellular carcinoma : Relevance to tumor dedifferentiation.2005

    • Author(s)
      Damdinsuren B, Nagano H, Kondo M, Yamamoto H, Hiraoka N, Yamamoto T, Marubashi S, Miyamoto A, Umeshita K, Dono K, Nakamori S, Wakasa K, Sakon M, Monden M.
    • Journal Title

      Int J Oncol 26

      Pages: 319-327

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Combination of interferon alpha and 5-fluorouracil induces apoptosis through interferon alpha/beta receptor in human hepatocellular carcinoma cells.2005

    • Author(s)
      Kondo M, Nagano H, Wada H, Damdinsuren B, Yamamoto H, Hiraoka N, Eguchi H, Miyamoto A, Yamamoto T, Ota H, Nakamura M, Marubashi S, Dono K, Umeshita K, Nakamori S, Sakon M, Monden M.
    • Journal Title

      Clinical Cancer Research 11

      Pages: 1277-1286

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Treatment of hepatocellular carcinoma with major portal vein thrombosis by combination of subcutaneous interferon-α and rintra-arterial 5-fluorouracil. Role of expression of type 1 inteiferon receptor2005

    • Author(s)
      Ota H, Nagano H, Sakon M, Eguchi H, Kondo M, Yamamoto T, Nakamura M, Damdinsuren B, Wada H, Marubashi, Miyamoto A, Dono K, Umeshita K, Nakamori S, Wakasa K, Monden M
    • Journal Title

      Br J Cancer 93(5)

      Pages: 557-564

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Association between tumor recurrence after surgery in patients with hepatocellular carcinoma and measurement of alpha-fetoprotein mRNA in peripheral blood but not bone marrow2005

    • Author(s)
      Morimoto O, Nagano H, Miyamoto A, Fujiwara Y, Kendo M, Yamamoto T, Ota H, Nakamura M, Wada H, Damdinsuren B, Marubashi S, Dono K, Umeshita K, Nakamori S, Sakon M, Monden M.
    • Journal Title

      Surgery Today 35(12)

      Pages: 1033-1041

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] 【消化器疾患における最近の話題 肝臓】 進行肝細胞癌の治療 予後の改善を考えて2004

    • Author(s)
      宮本敦史, 永野浩昭 他
    • Journal Title

      医学と薬学 52(5)

      Pages: 777-782

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] 【がんの化学療法 知っておきたい標準的治療法】 推薦処方とその解説 肝臓がん2004

    • Author(s)
      宮本敦史, 永野浩昭 他
    • Journal Title

      今月の治療 12(2)

      Pages: 191-193

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.

    • Author(s)
      Arai I, Nagano H, Kondo M, Yamamoto H, Hiraoka N, Sugita Y, Ota H, Yoshioka S, Nakamura M, Wada H, Damdinsuren B, Kato H, Marubashi S, Miyamoto A, Takeda Y, Dono K, Umeshita K, Nakamori S, Wakasa K, Sakon M, Monden M.
    • Journal Title

      Hepatogastroenterology (in press)

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Expression of type I Interferon Receptor as a Predictive Marker in Clinical Response of Interferon-α Treatment for Gastrointestinal Cancers

    • Author(s)
      Ota H, Nagano H, Doki Y, Sekimoto M, Kondo M, Wada H, Nakamura M, Noda T, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Dono K, Umeshita K, Nakamori S, Wakasa K, Monden M
    • Journal Title

      Oncology Reports (in press)

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Hepatic resection followed by IFN-α and 5-FU for advanced hepatocellular carcinoma with tumor thrombus in the major portal branch.

    • Author(s)
      Nagano H, Sakon M, Eguchi H, Kondo M, Yamamoto T, Ota H, Nakamura M, Wada H, Bazarragcha D, Marubashi S, Miyamoto A, Takeda Y, Keizo Dono, Umeshita K, Nakamori S, Monden M
    • Journal Title

      Hepatogastroenterology (in press)

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Clinical and Pathological Features of Allen's type C of Resected Combined Hepatocellular and Cholangiocarcinoma. A Comparative Study with Hepatocellular Carcinoma and Cholangiocellular Carcinoma

    • Author(s)
      Tang D, Nagano H, Nakamura M, Kondo M, Ota H, Wada H, Yoshioka S, Kato H, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Dono K, Monden M
    • Journal Title

      J Gastrointest Surg (in press)

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Journal Article] Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma : Importance of angiopoietin-2 and hypoxia-induced factor-1 □

    • Author(s)
      Wada H, Nagano H, Yamamoto H, Yang Y, Kondo M, Ota H, Nakamura M, Yoshioka S, Kato H, Damdinsuren B.Tang D, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Nakamori S, Sakon M, Dono K, Wakasa K, Monden M.
    • Journal Title

      Liver International (in press)

    • Data Source
      KAKENHI-PROJECT-16591314
  • [Presentation] IFNレセプター陽性肝細胞癌に対するIFN併用化学療法の感受性に関する遺伝子発現解析2008

    • Author(s)
      野田剛広, 永野浩昭, 竹政伊知朗, 吉岡慎一, 和田浩志, 村上昌裕, 小林省吾, 丸橋繁, 宮本敦史, 武田裕, 堂野恵三, 梅下浩司, 松原謙一, 門田守人
    • Organizer
      第108回日本外科学会定期学術集会
    • Place of Presentation
      (長崎)
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Presentation] 肝細胞癌肝切除および肝移植症例における末梢血中AFPMRNA定量の臨床的意義2008

    • Author(s)
      丸橋繁, 宮本敦史, 永野浩昭, 堂野恵三, 杉田ゆりか, 金致完, 浅岡忠史, 濱直樹, 小林省吾, 武田裕, 梅下浩司, 門田守人
    • Organizer
      第108回日本外科学会定期学術集会
    • Place of Presentation
      (長崎)
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Presentation] IFNレセプター陽性肝細胞癌に対するIFN併用化学療法の感受性に関する遺伝子発現解析2008

    • Author(s)
      野田剛広、永野浩昭、竹政伊知朗、吉岡慎一、和田浩志、村上昌裕、小林省吾、丸橋繁、宮本敦史、武田裕、堂野恵三、梅下浩司、松原謙一、門田守人
    • Organizer
      第108回日本外科学会定期学術集会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Presentation] 肝細胞癌に対するインターフェロン-α/5-FU併用化学療法の多角的抗腫瘍効果に対する検討2008

    • Author(s)
      永野浩昭, 野田剛広, 村上昌裕, 小林省吾, 丸橋繁, 宮本敦史, 武田裕, 山本浩文, 堂野恵三, 梅下浩司, 門田守人
    • Organizer
      第108回日本外科学会定期学術集会
    • Place of Presentation
      (長崎)
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Presentation] 肝細胞癌に対するインターフェロン-α/5-FU併用化学療法の多角的抗腫瘍効果に対する検討2008

    • Author(s)
      永野浩昭、野田剛広、村上昌裕、小林省吾、丸橋繁、宮本敦史、武田裕、山本浩文、堂野恵三、梅下浩司、門田守人
    • Organizer
      第108回日本外科学会定期学術集会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-19390350
  • [Presentation] 肝細胞癌肝切除および肝移植症例における末梢血中AFPMRNA定量の臨床的意義2008

    • Author(s)
      丸橋繁、宮本敦史、永野浩昭、堂野恵三、杉田ゆりか、金致完、浅岡忠史、濱直樹、小林省吾、武田裕、梅下浩司、門田守人
    • Organizer
      第108回日本外科学会定期学術集会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-19390350
  • 1.  MARUBASHI Shigeru (20362725)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 34 results
  • 2.  NAGANO Hiroaki (10294050)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 36 results
  • 3.  TAKEDA Yutaka (90397696)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 23 results
  • 4.  DONO Keizo (60283769)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 23 results
  • 5.  KOBAYASHI Syogo (30452436)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 6.  TAKAO Toshifumi (10197048)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TAKEMASA Ichiro (50379252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  MONDEN Morito (00127309)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results

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