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IHARA Masafumi  猪原 匡史

Researcher Number 00372590
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-7102-4048
Affiliation *help 2016 – 2017 : 国立研究開発法人国立循環器病研究センター, 病院, 部長
2016 : 国立循環器病研究センター, 脳血管内科, 医長
2015 : 国立研究開発法人国立循環器病研究センター, 病院, 医長
2013 – 2014 : 独立行政法人国立循環器病研究センター, 病院, 医長
2013 : 公益財団法人先端医療振興財団, その他部局等, 研究員 … More
2013 : 国立研究開発法人国立循環器病研究センター, 病院, 部長
2010 – 2012 : 京都大学, 医学(系)研究科(研究院), 助教
2012 : 公益財団法人先端医療振興財団, 先端医療センター 再生医療研究部, 副部長
2011 : 京都大学, 医学研究科, 助教
2004 : 京大, 医学(系)研究科(研究院) Less
Review Section/Research Field
Principal Investigator
Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology / Neurology / Structural biochemistry / Pathobiological dentistry/Dental radiology
Except Principal Investigator
Neurosurgery / Radiation science
Keywords
Principal Investigator
脳循環障害 / シロスタゾール / アルツハイマー病 / 血管性認知症 / 脳神経疾患 / 内皮型一酸化窒素合成酵素 / 両側総頸動脈狭窄術 / タキシフォリン / サーチュイン / 脳虚血 … More / 齲蝕原性細菌 / コラーゲン結合性 / 医師主導治験 / Tg-SwDIマウス / アミロイド / 痴呆 / 一酸化窒素 / 血液脳関門 / 循環器・高血圧 / アミロイド血管症 / オリゴマー / 抗糖化 / Notch3 / 連鎖球菌 / 脳梗塞 / 脳循環予備能 / 病理学 / アミロイドβ / 脳内微小出血 / SIRT1 / 臨床試験 / iPS細胞 / 脳卒中 / 微小梗塞 / ミュータンス菌 / 長寿遺伝子 / βアミロイド / タウ / 神経科学 / 細菌 / 脳・神経 / レスベラトロール / Sirt1 / モデルマウス / 抗糖化薬 / 歯学 / ナノメディシン / ドラッグディリバリー / CADASIL / 脳アミロイド血管症 / 認知症 / 口腔内細菌 / オートファジー … More
Except Principal Investigator
診断 / 脳アミロイドアンギオパチー / イメージング / 金属錯体 / 臨床 / βアミロイド / 脳神経疾患 / 内科 Less
  • Research Projects

    (10results)
  • Research Products

    (138results)
  • Co-Researchers

    (49People)
  •  Triple therapy prevention of Recurrent Intracerebral Disease EveNts TrialOngoing

    • Principal Investigator
      豊田 一則
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurosurgery
    • Research Institution
      National Cardiovascular Center Research Institute
  •  ナイジェリア、ケニアの脳卒中低減を目指した医科-歯科国際連携網の構築Principal InvestigatorOngoing

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  口腔内細菌に起因する出血性脳卒中の病態理解とモデル動物の作成Principal InvestigatorOngoing

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  細胞外タウ除去機構の破綻に基づくアルツハイマー病の病態解明と新規抗糖化療法の開発Principal InvestigatorOngoing

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Development of nuclear medical imaging probes targeting cerebral amyloid antipathy

    • Principal Investigator
      Ono Masahiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Kyoto University
  •  A study to elucidate the mechanism by which the longevity gene product SIRT1 confers neuroprotectionPrincipal Investigator

    • Principal Investigator
      IHARA Masafumi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Regenerative therapy for Alzheimer's disease and cerebral amyloid angiopathyPrincipal Investigator

    • Principal Investigator
      IHARA Masafumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      National Cardiovascular Center Research Institute
      Foundation for Biomedical Research and Innovation
      Kyoto University
  •  Exploration of treatment of hereditary vascular dementia CADASIL using patient-derived iPS cells and its model micePrincipal Investigator

    • Principal Investigator
      IHARA Masafumi
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  融合ナノプローブ薬剤送達システムを用いた脳虚血巣選択的オートファジー制御への挑戦Principal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  セプチン/脂質によるαシヌクレインポリマー/フィラメント形成機序に関する検討Principal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] モデル動物利用マニュアル.疾患モデルの作製と利用一循環器疾患2010

    • Author(s)
      北徹, 堀内久徳, 柳田素子, 猪原匡史, 冨本秀和, 並河徹編
    • Total Pages
      486
    • Publisher
      (株)エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Book] 慢性脳低灌流モデル.北徹, 堀内久徳, 柳田素子, 猪原匡史, 冨本秀和, 並河徹編「モデル動物利用マニュアル. 疾患モデルの作製と利用-循環器疾患」(株)

    • Author(s)
      猪原匡史, 冨本秀和
    • Total Pages
      486
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy2017

    • Author(s)
      Saito S, Yamamoto Y, Maki T, Hattori Y, Ito H, Mizuno K, Harada-Shiba M, Kalaria RN, Fukushima M, Takahashi R, Ihara M
    • Journal Title

      Acta Neuropathologica Communications

      Volume : 印刷中

    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Oral Cnm-positive Streptococcus Mutans Expressing Collagen Binding Activity is a Risk Factor for Cerebral Microbleeds and Cognitive Impairment.2016

    • Author(s)
      Watanabe I, Kuriyama N, Miyatani F, Nomura R, Naka S, Nakano K, Ihara M, Iwai K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Tamura A, Mizuno T, Akazawa K6, Takada A, Takeda K, Yamada K, Nakagawa M, Tanaka T, Kanamura N, Friedland RP, Watanabe Y.
    • Journal Title

      Scientific Reports

      Volume : 6 Pages : 1-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10318, KAKENHI-PROJECT-16K14573, KAKENHI-PROJECT-16H06277
  • [Journal Article] Gradual Carotid Artery Stenosis in Mice Closely Replicates Hypoperfusive Vascular Dementia in Humans.2016

    • Author(s)
      Hattori Y, Enmi J, Iguchi S, Saito S, Yamamoto Y, Tsuji M, Nagatsuka K, Kalaria RN, Iida H, Ihara M
    • Journal Title

      Journal of the American Heart Association

      Volume : 5

    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461867, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26640034
  • [Journal Article] Influence of low-dose aspirin on cerebral amyloid angiopathy in mice2016

    • Author(s)
      Hattori Y, Maki T, Saito S, Yamamoto Y, Nagatsuka K, Ihara M
    • Journal Title

      J Alzheimers Dis

      Volume : -

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] う蝕原因菌と脳出血の関連-脳口連関-.2016

    • Author(s)
      殿村修一,仲野和彦,猪原匡史
    • Journal Title

      日本歯科論評

      Volume : 76 Pages : 14-15

    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Journal Article] Frontal White Matter Hyperintensities, Clasmatodendrosis and Gliovascular Abnormalities in Ageing and Post-stroke Dementia2016

    • Author(s)
      13.Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung’u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, Polvikosk TM, Allan JM, Oakley AE, O’Brien JT, Horsburgh K, Ihara M, Kalaria RN
    • Journal Title

      Brain

      Volume : 139 Pages : 242-258

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory2016

    • Author(s)
      Kitamura A, Saito S, Maki A, Ayaki T, Oishi N, Kalaria RN, Hattori Y, Yamamoto Y, Urushitani M, Horsburgh K, Fukuyama H, Takahashi R, Ihara M
    • Journal Title

      J Cereb Blood Flow Metab

      Volume : - Pages : 1592-1602

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-15K09920, KAKENHI-PROJECT-26290023
  • [Journal Article] Hemisphere asymmetry of response to treatment in an Alzheimer’s disease mouse model2016

    • Author(s)
      Manousopoulou A, Saito S, Yamamoto Y, Al-Daghri NM, Ihara M, Carare RO, Garbis SD
    • Journal Title

      J Alzheimers Dis

      Volume : 21 Pages : 333-338

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
  • [Journal Article] Emerging evidence for pathogenesis of sporadic cerebral small vessel disease2016

    • Author(s)
      Ihara M, Yamamoto Y
    • Journal Title

      Stroke

      Volume : 47 Pages : 554-560

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-16K18387
  • [Journal Article] Stroke Injury, cognitive Impairment and vascular dementia2016

    • Author(s)
      Kalaria RN, Akinyemi R, Ihara M
    • Journal Title

      Biochim Biophys Acta

      Volume : -

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Interaction between cerebrovascular disease and Alzheimer pathology2016

    • Author(s)
      Saito S, Ihara M
    • Journal Title

      Curr Opin Psychiatry

      Volume : 29 Pages : 168-173

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
  • [Journal Article] SIRT1 attenuates severe ischemic damage by preserving cerebral blood flow.2015

    • Author(s)
      Hattori Y, Okamoto Y, Nagatsuka K, Takahashi R, Kalaria RN, Kinoshita M, Ihara M
    • Journal Title

      NeuroReport

      Volume : 26 Pages : 113-117

    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26640034, KAKENHI-PLANNED-23111002
  • [Journal Article] Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents that Selectively Detect Neurofibrillary Tangles in Alzheimer’s Disease Brains2015

    • Author(s)
      Matsumura K, Ono M, Kitada A, Watanabe H, Yoshimura M, Iikuni S, Kimura H, Okamoto Y, Ihara M, Saji H.
    • Journal Title

      J Med Chem

      Volume : 58 Pages : 7241-7257

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01555, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-14J05961
  • [Journal Article] Immunolocalisation of PDGFRβ and pericytes in CADASIL2015

    • Author(s)
      Craggs LJL, Fenwick R, Oakley AE, Ihara M, Kalaria RN
    • Journal Title

      Neuropath Appl Neurobiol

      Volume : 41 Pages : 557-570

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Mild cognitive impairment: at the crossroad of neurodegeneration and vascular dysfunction2015

    • Author(s)
      Saito S, Yamamoto Y, Ihara M
    • Journal Title

      Curr Alzheimer Res

      Volume : 12 Pages : 507-512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
  • [Journal Article] Translation of pre-clinical studies into successful clinical trials for Alzheimer’s disease: what are the roadblocks and how can they be overcome?2015

    • Author(s)
      Banik A, Brown RE, Bamburg J, Lahiri DK, Khurana D, Friedland RP, Chen W, Ding Y, Mudher A, Padjen AL, Mukaetova-Ladinska E, Ihara M, Srivastava E, Srivastava MVP, Masters CL, Kalaria RN, Anand A
    • Journal Title

      J Alzheimer Dis

      Volume : 47 Pages : 815-843

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.2015

    • Author(s)
      Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ramírez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fernández-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J.
    • Journal Title

      J Neurosci.

      Volume : 35(44) Pages : 14717-26

    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26293186
  • [Journal Article] A novel mouse model of subcortical infarcts with dementia.2015

    • Author(s)
      Hattori Y, Enmi J, Kitamura A, Yamamoto Y, Saito S, Takahashi Y, Iguchi S, Tsuji M, Yamahara K, Nagatsuka K, Iida H, Ihara M
    • Journal Title

      The Journal of Neuroscience

      Volume : 35 Pages : 3915-3928

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461867, KAKENHI-PROJECT-25640031
  • [Journal Article] Motor and cognitive impairment in a mouse model of ischemic carotid artery disease.2014

    • Author(s)
      Hattori Y, Kitamura A, Tsuji M, Nagatsuka K, Ihara M
    • Journal Title

      Neurosci Lett

      Volume : 581 Pages : 1-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] Cilostazol add-on therapy in patients with mild dementia receiving donepezil : a retrospective study2014

    • Author(s)
      Ihara M, Nishino M, Taguchi A, Yamamoto Y, Hattori Y, Saito S, Takahashi Y, Tsuji M, Kasahara Y, Takata Y, Okada M
    • Journal Title

      PloS ONE

      Volume : 9(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid.2014

    • Author(s)
      Maki T, Okamoto Y, Carare RO, Hase Y, Hattori Y, Hawkes CA, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda H, Taguchi A, Takahashi R, Miyakawa T, Kalaria RN, Lo EH, Arai K, Ihara M
    • Journal Title

      Ann Clin Transl Neurol

      Volume : 1 Pages : 519-533

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] 注目される脳小血管病による認知症2014

    • Author(s)
      猪原匡史
    • Journal Title

      Dementia Japan

      Volume : 28(1) Pages : 57-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] 注目される脳小血管病による認知症.2014

    • Author(s)
      猪原匡史
    • Journal Title

      Dementia Japan

      Volume : 28 Pages : 57-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Silent Information Regulator 2 Homolog 1 Counters Cerebral Hypoperfusion Injury by Deacetylating Endothelial Nitric Oxide Synthase2014

    • Author(s)
      Hattori Y, Okamoto Y, Maki T, Yamamoto Y, Oishi N, Yamahara K, Nagatsuka K, Takahashi R, Kalaria RN, Fukuyama H, Kinoshita M, Ihara M
    • Journal Title

      Stroke

      Volume : 45 Pages : 3403-3411

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390292, KAKENHI-PROJECT-24791296, KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26640034, KAKENHI-PROJECT-22220003
  • [Journal Article] 高血糖とアルツハイマー病.2014

    • Author(s)
      猪原匡史
    • Journal Title

      医学のあゆみ

      Volume : 249 Pages : 545-550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Effects of intravenous administration of umbilical cord blood CD34+ cells in a mouse model of neonatal stroke.2014

    • Author(s)
      Tsuji M, Taguchi A, Ohshima M, Kasahara Y, Sato Y, Tsuda H, Otani K, Yamahara K, Ihara M, Harada-Shiba M, Ikeda T, Matsuyama T.
    • Journal Title

      Neuroscience

      Volume : 263 Pages : 148-158

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23500448, KAKENHI-PROJECT-23791220, KAKENHI-PROJECT-24591617, KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26461630
  • [Journal Article] White matter pathology and disconnection in the frontal lobe in CADASIL.2014

    • Author(s)
      Craggs LJ, Yamamoto Y, Ihara M, Fenwick R, Slade JY, Oakley A, Roeber S, Duering M, Kretzschmar H, Kalaria RN.
    • Journal Title

      Neuropath Appl Neurobiol

      Volume : in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-12J07954, KAKENHI-PROJECT-23390233
  • [Journal Article] 注目される脳小血管病による認知症.2014

    • Author(s)
      猪原匡史
    • Journal Title

      Dementia Japan

      Volume : 28 Pages : 57-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] 高血糖とアルツハイマー病.2014

    • Author(s)
      猪原匡史
    • Journal Title

      医学のあゆみ

      Volume : 249 Pages : 545-550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] A mouse model of chronic cerebral hypoperfusion characterizing features of cognitive impairment2014

    • Author(s)
      Ihara M, Taguchi A, Maki T, Washida K, Tomimoto H
    • Journal Title

      Methods Mol Biol

      Volume : 1135 Pages : 95-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] 認知症における血管病の重要性.2013

    • Author(s)
      猪原匡史
    • Journal Title

      脳循環代謝

      Volume : 24 Pages : 83-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Synthesis and biological evaluation of novel styryl benzimidazole derivatives as probes for imaging of neurofibrillary tangles in Alzheimer's disease.2013

    • Author(s)
      Matsumura K, Ono M, Yoshimura M, Kimura H, Watanabe H, Okamoto Y, Ihara M, Takahashi R, Saji H.
    • Journal Title

      Bioorg Med Chem

      Volume : 21 Pages : 3356-3362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-24659564, KAKENHI-PROJECT-25640031
  • [Journal Article] 認知症における血管病の重要性2013

    • Author(s)
      猪原匡史
    • Journal Title

      脳循環代謝

      Volume : 24(2) Pages : 83-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] 認知症の診断と治療を目指した小血管病の管理2013

    • Author(s)
      猪原匡史
    • Journal Title

      Brain and Nerve

      Volume : 65(7) Pages : 801-809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] An highly reproducible model of cerebralischemia/reperfusion with extended survival in CB-17 mice2013

    • Author(s)
      Kasahara Y, Ihara M, Nakagomi T, Momota Y, Sterm D, Matsuyama T, Taguchi A
    • Journal Title

      Neurosci Res

      Volume : 76 Pages : 163-168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592271, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23500448, KAKENHI-PROJECT-25463159, KAKENHI-PROJECT-25640031
  • [Journal Article] Structure-activity Relationships and in vivo Evaluation of Quinoxaline Derivatives for PET Imaging of β-Amyloid Plaques.2013

    • Author(s)
      Yoshimura M, Ono M, Matsumura K, Watanabe H, Kimura H, Cui M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H.
    • Journal Title

      ACS Med Chem Lett

      Volume : 4 Pages : 596-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Experimental and clinical challenge for neuroregeneration following stroke.2013

    • Author(s)
      Kasahara Y, Ihara M, Taguchi A.
    • Journal Title

      Front Neurol Neurosci

      Volume : 32 Pages : 69-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Vascular and neurodegenerative pathways-will they meet?2013

    • Author(s)
      Kalaria RN, Ihara M
    • Journal Title

      Nat Rev Neurol

      Volume : 9(9) Pages : 487-488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Suitability of the Montreal Cognitive Assessment versus the Mini-Mental State Examination in Detecting Vascular Cognitive Impairment.2013

    • Author(s)
      Ihara M, Okamoto Y, Takahashi R
    • Journal Title

      Journal of stroke and cerebrovascular diseases

      Volume : 22 Issue : 6 Pages : 737-741

    • Publisher
      Elsevier Inc.
    • PMID
      22306380
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-23650182
  • [Journal Article] Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer's Disease.2013

    • Author(s)
      Ono M, Cheng Y, Kimura H, Watanabe H, Matsumura K, Yoshimura M, Iikuni S, Okamoto Y, Ihara M, Takahashi R, Saji H.
    • Journal Title

      PLoS One

      Volume : 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Visualization of Lenticulostriate Arteries by Flow-Sensitive Black-Blood MR Angiography on a 1.5T MRI System: A Comparative Study between Subjects with and without Stroke. AJNR Am J Neuroradiol.2013

    • Author(s)
      Okuchi S
    • Journal Title

      AJNR Am J Neuroradiol

      Volume : 34 Pages : 780-784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-24591757, KAKENHI-PROJECT-25640031, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002
  • [Journal Article] 認知症における血管病の重要性.2013

    • Author(s)
      猪原匡史
    • Journal Title

      脳循環代謝

      Volume : 24 Pages : 83-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] 認知症の診断と治療を目指した小血管病の管理2013

    • Author(s)
      猪原匡史
    • Journal Title

      Brain and Nerve

      Volume : 65 Pages : 801-809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] Association of Physical Activity with the Visuospatial/Executive Functions of the Montreal Cognitive Assessment in Patients with Vascular Cognitive Impairment2013

    • Author(s)
      Ihara M, Okamoto Y, Hase Y, Takahashi R
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume : 22(7)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Vascular Risk Factors and Neurodegeneration in Ageing related Dementias : Alzheimer' s Disease and Vascular Dementia2013

    • Author(s)
      Akinyemi R, Mukaetova-Ladinska E, Attems J, Ihara M, Kalaria RN
    • Journal Title

      Curr Alzheimer Res

      Volume : 10(6) Pages : 642-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Cilostazol improves cognitive function in patients with mild cognitive impairment : A retrospective analysis2013

    • Author(s)
      Taguchi A, Takata Y, Ihara M, Kasahara Y, Tsuji M, Nishino M, Stern D, Okada M
    • Journal Title

      Psychogeriatrics

      Volume : 13(3) Pages : 164-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Cilostazol, a phosphodiesterase inhibitor, prevents no-reflow and hemorrhage in mice with focal cerebral ischemia2012

    • Author(s)
      Hase Y, Okamoto Y, Fujita Y, KitamuraA, Ito H, Maki T, Washida K, TakahashiR, Ihara M
    • Journal Title

      Experimental Neurology

      Volume : 233 Pages : 523-533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Selective white matter abnormalities in a novel rat model of vascular dementia.2012

    • Author(s)
      Kitamura A, Fujita Y, Oishi N, KalariaR N, Washida K, Maki T, Okamoto Y, HaseY, Yamada M, Takahashi J, Ito H, Tomimoto H, Fukuyama H, Takahashi R, Ihara M
    • Journal Title

      Neurobiology of aging

      Volume : 33 Issue : 5 Pages : 1012.e25-1012.e35

    • Publisher
      Elsevier Inc.
    • PMID
      22133276
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22220003, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice.2012

    • Author(s)
      Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, ShimohamaS, Kihara T, Kinoshita A
    • Journal Title

      Neurobiology of aging

      Volume : 33 Issue : 5 Pages : 1011.e11-1011.e23

    • Publisher
      Elsevier Inc.
    • PMID
      22197104
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23591243, KAKENHI-PROJECT-23650182, KAKENHI-PUBLICLY-24111524
  • [Journal Article] Cerebral hypoperfusion induces microinfarcts in cerebral amyloid angiopathy2012

    • Author(s)
      Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, Kitamura A, Washida K, Yamada M, Ito H, Tomimoto H, Takahashi R, Ihara M
    • Journal Title

      Acta Neuropathol

      Volume : 123(3) Pages : 381-394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] 18F-labeled Phenyldiazenyl Benzothiazole for invivo Imaging of Neurofibrillary Tangles in Alzheimer's Disease Brains2012

    • Author(s)
      Matsumura K, Ono M, Kimura H, Ueda M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H
    • Journal Title

      ACS Med Chem Lett

      Volume : 3(1) Pages : 58-62

    • Data Source
      KAKENHI-PROJECT-23650182
  • [Journal Article] Angiogenic roles of adreno medullin through VEGF induction2011

    • Author(s)
      Maki T, Ihara M, Fujita Y, Nambu T, Harada H, Ito H, Nakao K, Tomimoto H, Takahashi R
    • Journal Title

      Neuroreport

      Volume : 22 Pages : 442-447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] An autopsy case of SOD1-related ALS with TDP-43 positive inclusions2011

    • Author(s)
      Okamoto Y, Ihara M, Urushitani M, Yamashita H, Kondo T, Tanigaki A, Oono M, Kawamata J, Ikemoto A, Kawamoto Y, Takahashi R, Ito H
    • Journal Title

      Neurology

      Volume : 77:1993-1995 Pages : 1993-1995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing Mice.2011

    • Author(s)
      Yamada M, Ihara M, Okamoto Y, Maki T, Washida K, Kitamura A, Hase Y, Ito H, Takao K, Miyakawa T, Kalaria RN, Tomimoto H, Takahashi R
    • Journal Title

      PloS one

      Volume : 6 Issue : 1

    • Publisher
      Public Library of Science(PLoS)
    • PMID
      21305033
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233
  • [Journal Article] Colocalization of 14-3-3 Proteins with SOD1 in Lewy Body-Like Hyaline Inclusions in Familial Amyotrophic Lateral Sclerosis Cases and the Animal Model.2011

    • Author(s)
      Okamoto Y, Shirakashi Y, Ihara M, Urushitani M, Oono M, Kawamoto Y, Yamashita H, Shimohama S, Kato S, Hirano A, Tomimoto H, Ito H, Takahashi R
    • Journal Title

      PloS one

      Volume : 6 Issue : 5

    • Publisher
      Public Library of Science
    • PMID
      21655264
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] The influence of chronic cerebral hypoperfusion on cognitive function and amyloid β metabolism in APP overexpressing mice.2011

    • Author(s)
      Yamada M, Ihara M, et.al.
    • Journal Title

      PLoS One

      Volume : 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice.2011

    • Author(s)
      Maki T, Ihara M, et al.
    • Journal Title

      Stroke

      Volume : 42 Pages : 1125-1131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011

    • Author(s)
      Maki T, Tomimoto H
    • Journal Title

      Stroke

      Volume : 42(4) Pages : 1122-1128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005, KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Selective white matter pathology induces a specific impainnent in spatial working memory2011

    • Author(s)
      Coltman R, Spain A, et al
    • Journal Title

      Neurobiol Aging

      Volume : 32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains2011

    • Author(s)
      Ono M, Hayashi S, et al
    • Journal Title

      ACS Chem Neurosci

      Volume : 2 Pages : 269-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Phenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer's disease brains2011

    • Author(s)
      Matsumura K, Ono M, et al
    • Journal Title

      Med Chem Comm

      Volume : 2 Pages : 596-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation2011

    • Author(s)
      Ito H, Nakamura M, Komure O, Ayaki T, Wate R, Maruyama H, Nakamura Y, FujitaK, Kaneko S, Okamoto Y, Ihara M, Konishi T, Ogasawara K, Hirano A, Kusaka H, KajiR, Takahashi R, Kawakami H
    • Journal Title

      Acta Neuropathologica

      Volume : 122 Pages : 223-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23591246, KAKENHI-PROJECT-23650182
  • [Journal Article] Watershed infarcts in a multiple microembolic model of monkey.2011

    • Author(s)
      Maki T, Wakita H, Mase M, Itagaki I, Saito N, Ono F, Adachi K, Ito H, Takahashi R, Ihara M, Tomimoto H
    • Journal Title

      Neuroscience letters

      Volume : 499 Issue : 2 Pages : 80-83

    • Publisher
      Elsevier Ireland Ltd.
    • PMID
      21640789
    • Year and Date
      2011-07-20
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-21591106, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes2011

    • Author(s)
      Ihara M, Tomimoto H
    • Journal Title

      J Aging Res

      Volume : 2011 Pages : 978761-978761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to PPAR-γ activation in mice with chronic cerebral hypoperfusion.2010

    • Author(s)
      Washida K, Ihara M, et al.
    • Journal Title

      Stroke

      Volume : 41 Pages : 1798-1806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Early protective effect of bone marrow mononuclear cells against ischemic white matter damage through augmentation of cerebral blood flow.2010

    • Author(s)
      Fujita Y, Ihara M, et al.
    • Journal Title

      Stroke

      Volume : 41 Pages : 2938-2943

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies.2010

    • Author(s)
      Ihara M, Plvikoski TM, et al.
    • Journal Title

      Acta Neuropathol

      Volume : 119 Pages : 579-589

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] A mouse model characterizing features of vascular dementia with hippocampal atrophy.2010

    • Author(s)
      Nishio K, Ihara M, et al.
    • Journal Title

      Stroke

      Volume : 41 Pages : 1278-1284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] 脳血管障害による認知機能障害;Vascular cognitive impairment2010

    • Author(s)
      猪原匡史
    • Journal Title

      老年精神医学雑誌

      Volume : 22 Pages : 53-59

    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] 脳血管障害に基づく認知機能障害の病態2010

    • Author(s)
      猪原匡史, 岡本洋子, ら
    • Journal Title

      脳卒中

      Volume : 32 Pages : 614-620

    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] 亜急性に進行する発動性低下のみを呈した内包膝部branch atheromatous diseaseの一例2010

    • Author(s)
      北村彰浩, 猪原匡史, ら
    • Journal Title

      脳卒中

      Volume : 32 Pages : 384-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] 高血糖とアルツハイマー病

    • Author(s)
      猪原匡史
    • Journal Title

      医学のあゆみ

      Volume : (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β -amyloid

    • Author(s)
      Maki T, Okamoto Y, Carare R, Hase Y, Hattori Y, Hawkes C, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda, H, Taguchi A, Takahashi R, Miyakawa T, Kalaria R, Lo E, Arai K, Ihara M
    • Journal Title

      Ann Clin Transl Neurol

      Volume : (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Vascular Dementia2017

    • Author(s)
      Masafumi Ihara
    • Organizer
      International Stroke Conference
    • Place of Presentation
      Houston, USA
    • Year and Date
      2017-02-21
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Presentation] Dental microbes and stroke/dementia.2016

    • Author(s)
      Masafumi Ihara
    • Organizer
      Brain Ageing and Dementia in LIMICS 2016
    • Place of Presentation
      Nairobi, Kenya
    • Year and Date
      2016-12-06
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Presentation] 脳卒中の新たな危険因子-口腔内感染-.2016

    • Author(s)
      猪原匡史
    • Organizer
      日本神経学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Presentation] Bone morphogenetic protein‐4 expression by pericytes correlates with white matter damage in dementing disorders2015

    • Author(s)
      Masafumi Ihara
    • Organizer
      Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kobe
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] ドラッグ・リポジショニングの手法を用いた軽度認知障害に対する創薬戦略2015

    • Author(s)
      猪原匡史
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] Experimental evidence linking vascular factors to Alzheimer's disease2015

    • Author(s)
      Masafumi Ihara
    • Organizer
      Alzheimer's Association International Conference (AAIC)
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2015-07-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] Animal Model of VCI2015

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog International
    • Place of Presentation
      Tokyo
    • Year and Date
      2015-09-16
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] Vascular Cognitive Impairment2015

    • Author(s)
      猪原匡史
    • Organizer
      第20回認知神経科学会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] 血管病を標的とした認知症治療2015

    • Author(s)
      猪原匡史
    • Organizer
      第5回認知症予防学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] Symposium S(4) -1. Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment (VCI) . Cerebral amyloid angiopathy and cognitive impairment2013

    • Author(s)
      Ihara M
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2013-06-01
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題2013

    • Author(s)
      Ihara M
    • Organizer
      Novel mechanism and therapy to treat patient with dementia. Neuro2013
    • Place of Presentation
      京都
    • Year and Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Bench to bedside : using mouse models to identify new treatment approaches for Alzheimer' s disease2013

    • Author(s)
      Ihara M
    • Organizer
      Invited lecture : 19th Southampton Neuroscience Group (SoNG) Meeting
    • Place of Presentation
      Southampton, UK
    • Year and Date
      2013-09-19
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment2013

    • Author(s)
      Ihara M
    • Organizer
      Minisymposium (Animal models of VCI) . Vas-Cog2013
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2013-06-26
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment2013

    • Author(s)
      Ihara M
    • Organizer
      Plenary session (Special session on animal models of VCI) . Vas-Cog2013
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2013-06-26
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] βアミロイドの血管依存性クリアランス2011

    • Author(s)
      猪原匡史
    • Organizer
      日本認知症学会学術集会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] モントリオール認知評価法MoCAはMMSEよりも皮質下血管性認知障害の検出感度が高い2011

    • Author(s)
      猪原匡史
    • Organizer
      日本神経学会総会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Animal models for vascular cognitive impairment due to large vessel disease. Stroke Symposium in National University of Singapore2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Stroke Symposium in National University of Singapore
    • Place of Presentation
      Singapore(招待講演)
    • Year and Date
      2011-10-31
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Angiogenic and vasoprotectivc effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog2011
    • Place of Presentation
      France
    • Year and Date
      2011-09-14
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Animal models for vascular cognitive impairment due to large vessel disease2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      STROKE SYMPOSIUM
    • Place of Presentation
      Singapore(CELS Auditorium)
    • Year and Date
      2011-10-31
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] Angiogenic andvasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog
    • Place of Presentation
      Lille, France
    • Year and Date
      2011-09-14
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] βアミロイドの血管依存性クリアランス2011

    • Author(s)
      猪原匡史
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] 脳低灌流によりβアミロイドの血管依存性クリアランスが障害される2011

    • Author(s)
      猪原匡史, 岡本洋子, 眞木崇州, 鷲田和夫, 伊東秀文, 冨本秀和, 高橋良輔
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] モントリオール認知評価法MoCAはMMSEよりも皮質下血管性認知障害の検出感度が高い2011

    • Author(s)
      猪原匡史, 岡本洋子, 伊東秀文, 高橋良輔
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] 脳低灌流によりβアミロイドの血管依存性クリアランスが障害される2011

    • Author(s)
      猪原匡史, 他
    • Organizer
      日本認知症学会学術集会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 皮質下血管性認知症患者におけるモントリオール認知評価スコアと身体活動度との相関2011

    • Author(s)
      猪原匡史
    • Organizer
      第30回日本認知症学会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] Animal models forvascular cognitive impairment due tolarge vessel disease2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Stroke Symposiumin National University of Singapore(Invited lecture)
    • Place of Presentation
      Singapore
    • Year and Date
      2011-10-31
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] Poster review session.2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog
    • Place of Presentation
      Lille, France
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] A Mouse Model Characterizing Features of Vascular Dementia with Hippocampal Atrophy2010

    • Author(s)
      Masafumi Ihara
    • Organizer
      International Congress of Neuropathology (ICN2010)
    • Place of Presentation
      Salzburg, Austria
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] 海馬萎縮を伴う血管性認知症の新規モデルマウス2010

    • Author(s)
      猪原匡史
    • Organizer
      日本脳循環代謝学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] Animal models to study Stroke and VCI.2010

    • Author(s)
      Masafumi Ihara
    • Organizer
      Annual Neurosciences Conference in Eastern Africa
    • Place of Presentation
      Nairobi, Kenya
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] 混合型認知症の位置づけ, Vascular cognitive impairment(VCI)2010

    • Author(s)
      猪原匡史
    • Organizer
      日本認知症学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] シロスタゾールの血液脳関門保護効果-一過性局所脳虚血モデルにおけるVirchow血栓形成3要因への作用について-2010

    • Author(s)
      猪原匡史
    • Organizer
      日本脳循環代謝学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] CADASIL側頭極病変の成因に関する病理学的研究2010

    • Author(s)
      猪原匡史, 山本由美, ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] シロスタゾールの血液脳関門保護効果:一過性局所脳虚血モデルから得られたエビデンス2010

    • Author(s)
      猪原匡史
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] 脳血管障害に基づく認知機能障害の病態2010

    • Author(s)
      猪原匡史
    • Organizer
      日本脳卒中学会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-15
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] 「長寿遺伝子」SIRT1はeNOSを脱アセチル化することで脳低灌流侵襲に対する抵抗性を賦与する

    • Author(s)
      猪原匡史
    • Organizer
      脳卒中学会
    • Place of Presentation
      広島
    • Year and Date
      2015-03-26 – 2015-03-29
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] 「血管病としての認知症」

    • Author(s)
      猪原匡史
    • Organizer
      Vas-Cog Japan
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] シロスタゾールによる血管依存性βアミロイドクリアランスの促進.

    • Author(s)
      猪原匡史
    • Organizer
      脳循環代謝学会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Symposium S(4)-1.Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment (VCI).Cerebral amyloid angiopathy and cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Novel mechanism and therapy to treat patient with dementia. Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] 認知症における脳血管病変

    • Author(s)
      猪原匡史
    • Organizer
      第3回VAS-COG Japan 2012
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 小血管病における虚血性線条体障害:11C-フルマゼニルPETによる解析

    • Author(s)
      猪原匡史
    • Organizer
      第5回J-CAN (Japanese Consortium for Age-related Neurodegenerative disorders) 2012
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] シンポジウム1.血管性認知症の最先端「血管性認知症とAlzheimer病理」

    • Author(s)
      猪原匡史
    • Organizer
      第31回日本認知症学会学術集会
    • Place of Presentation
      つくば
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 血管病としての認知症~その制圧へ向けた試み~

    • Author(s)
      猪原匡史
    • Organizer
      第3回VAS-COG Japan 2012
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical

    • Author(s)
      Masafumi Ihara
    • Organizer
      World Stroke Congress
    • Place of Presentation
      Brazilia
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Animal models of brain hypoperfusion and cognitive impairment

    • Author(s)
      Masafumi Ihara
    • Organizer
      BRAIN AGEING AND DEMENTIA IN DEVELOPING COUNTRIES 2012
    • Place of Presentation
      Nairobi
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 皮質下血管性認知症患者におけるモントリオール認知評価スコアと身体活動度との相関

    • Author(s)
      猪原匡史
    • Organizer
      第53回日本神経学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 認知症患者における抗血栓療法の有効性と安全性に関する分子病理学的検討

    • Author(s)
      猪原匡史
    • Organizer
      第37回日本脳卒中学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 「血管病としての認知症」

    • Author(s)
      猪原匡史
    • Organizer
      Vas-Cog Japan
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Novel mechanism and therapy to treat patient with dementia. Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Minisymposium (Animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 「認知症の発症にかかわる脳血管の機能」.

    • Author(s)
      猪原匡史
    • Organizer
      脳心血管抗加齢研究会2013
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] シロスタゾールによる血管依存性βアミロイドクリアランスの促進.

    • Author(s)
      猪原匡史
    • Organizer
      脳循環代謝学会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Bench to bedside: using mouse models to identify new treatment approaches for Alzheimer’s disease.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Invited lecture: 19th Southampton Neuroscience Group (SoNG) Meeting
    • Place of Presentation
      Southampton
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Symposium S(4)-1.Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment (VCI).Cerebral amyloid angiopathy and cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical

    • Author(s)
      Masafumi Ihara
    • Organizer
      3rd CAA meeting (Plenary lecture)
    • Place of Presentation
      Leiden
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] シンポジウム5「血管性認知障害」血管性認知障害の病態-モデル動物を用いて明らかとなった知見-

    • Author(s)
      猪原匡史
    • Organizer
      第39回日本脳卒中学会総会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Plenary session (Special session on animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Minisymposium (Animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Bench to bedside: using mouse models to identify new treatment approaches for Alzheimer’s disease.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Invited lecture: 19th Southampton Neuroscience Group (SoNG) Meeting
    • Place of Presentation
      Southampton
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] シンポジウム5「血管性認知障害」血管性認知障害の病態-モデル動物を用いて明らかとなった知見-

    • Author(s)
      猪原匡史
    • Organizer
      第39回日本脳卒中学会総会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] 「認知症の発症にかかわる脳血管の機能」.

    • Author(s)
      猪原匡史
    • Organizer
      脳心血管抗加齢研究会2013
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Plenary session (Special session on animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
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    # of Collaborated Projects : 2results
    # of Collaborated Products : 2results
  • 2.  TOMIMOTO Hidekazu (80324648)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 9results
  • 3.  Ono Masahiro (80336180)
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    # of Collaborated Products : 2results
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    # of Collaborated Products : 3results
  • 19.  MATSUMURA Kenji
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    # of Collaborated Products : 12results
  • 24.  Hattori Yorito
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    # of Collaborated Products : 3results
  • 25.  OISHI Naoya
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