Shima Tomoko 島友子

… Alternative Names

SHIMA Tomoko 島友子

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Researcher Number	00377285
Affiliation (Current)	2025: 富山大学, 学術研究部医学系, 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 富山大学, 学術研究部医学系, 講師 2019 – 2022: 富山大学, 学術研究部医学系, 助教 2018: 富山大学, 大学院医学薬学研究部(医学), 助教 2017: 富山大学, 医学薬学研究部(医学), 助教 2017: 富山大学, 医学部附属病院, その他 … More 2014 – 2016: 富山大学, 大学院医学薬学研究部(医学), 助教 2015: 富山大学, 医学薬学研究部(医学), 助教 2012: 富山大学, 大学院・医学薬学研究部(医学), 助教 2011 – 2012: 富山大学, 大学院医学薬学研究部(医学), 助教 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 精漿 / 父親抗原特異的制御性T細胞 / 母児免疫寛容 / 免疫寛容誘導性樹状細胞 / 制御性T細胞 / NK細胞 / 樹状細胞 / 制御性樹状細胞 / 妊娠維持 / 胎児(父親)抗原特異的制御性T細胞 … More Except Principal Investigator … More オートファジー / 妊娠高血圧症候群 / Atg4B / 妊娠高血圧腎症 / TFEB / リソソーム傷害 / 胎盤形成不全 / hypoxia / ER stress / preeclampsia / autophagy / 合胞体化 / 小胞体ストレス / リソソーム / トランスサイレチン / 胎盤成長因子 / 胎児発育遅延 / 胎盤 / ERストレス Less

妊娠高血圧腎症におけるオートファジー不全と母児免疫寛容誘導メカニズムの解明Principal Investigator
- Principal Investigator
  
  島友子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Toyama
Failure of autophagy for the therapeutic target of preeclampsia
- Principal Investigator
  
  中島彰俊
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Toyama
the better understanding of the mechanism of maternal immune tolerance induction by regulatory T cells, dendritic cells, and NK cellsPrincipal Investigator
- Principal Investigator
  
  Shima Tomoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Toyama
New mechanism of autophagy inhibition from the study of preeclampsia
- Principal Investigator
  
  NAKASHIMA Akitoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Toyama
The crosstalk of paternal antigen specific Treg cells and dendritic cells in feto-maternal tolerancePrincipal Investigator
- Principal Investigator
  
  Shima Tomoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
The development of new therapy for preeclampsia via modulation of autophagy
- Principal Investigator
  
  Nakashima Akitoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
The role of seminal fuid in paternal antigen specific feto-maternal tolerancePrincipal Investigator
- Principal Investigator
  
  Shima Tomoko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
The importance of fetal antigen specific regulatory T cells in allogeneic pregnancyPrincipal Investigator
- Principal Investigator
  
  SHIMA Tomoko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2012 2011 Other

All Journal Article Presentation Book

[Book] Preeclampsia Basic, Genomic, and Clinical2018
- Author(s)
  Akitoshi Nakashima
- Total Pages
  290
- Publisher
  Springer
- ISBN
  9789811058905
- Data Source
  KAKENHI-PROJECT-16K11082
[Book] Preeclampsia Basic, Genomic, and Clinical2018
- Author(s)
  Akitoshi Nakashima, Shigeru Saito et al
- Total Pages
  290
- Publisher
  Springer
- ISBN
  9789811058905
- Data Source
  KAKENHI-PROJECT-16K11082
[Journal Article] Immunological regulation and the role of autophagy in preeclampsia2024
- Author(s)
  Nakashima Akitoshi、Furuta Atsushi、Yoshida‐Kawaguchi Mihoko、Yamada Kiyotaka、Nunomura Haruka、Morita Keiko、Yasuda Ippei、Yoneda Satoshi、Yamaki‐Ushijima Akemi、Shima Tomoko、Tsuda Sayaka
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 91 Issue: 3
- DOI
  10.1111/aji.13835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0287, KAKENHI-PROJECT-21K09535, KAKENHI-PROJECT-21K16764, KAKENHI-PROJECT-23K24482
[Journal Article] The Role of Autophagy in the Female Reproduction System: For Beginners to Experts in This Field2023
- Author(s)
  Nakashima Akitoshi、Furuta Atsushi、Yamada Kiyotaka、Yoshida-Kawaguchi Mihoko、Yamaki-Ushijima Akemi、Yasuda Ippei、Ito Masami、Yamashita Satoshi、Tsuda Sayaka、Yoneda Satoshi、Cheng Shibin、Sharma Surendra、Shima Tomoko
- Journal Title
  
  Biology
  
  Volume: 12 Issue: 3 Pages: 373-373
- DOI
  10.3390/biology12030373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24482
[Journal Article] 当科における卵巣癌の予後と維持化学療法の有効性の評価2023
- Author(s)
  竹内麻優子, 安田一平, 伊東雅美, 竹村京子, 島友子, 中島彰俊.
- Journal Title
  
  富山県産科婦人科学会雑誌.
  
  Volume: 39 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24482
[Journal Article] Chloroquine is a safe autophagy inhibitor for sustaining the expression of antioxidant enzymes in trophoblasts.2023
- Author(s)
  Furuta A, Shima T, Yoshida-Kawaguchi Mihoko, Yamada K, Yasuda I, Tsuda S, Yamaki-Ushijima A, Yonede S, Higashisaka K, Cheng SB, Matsumoto K, Tsutsumi Y, Sharma S, Saito S, Nakashima A
- Journal Title
  
  J Reprod Immunol.
  
  Volume: 155 Pages: 103766-103766
- DOI
  10.1016/j.jri.2022.103766
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16764, KAKENHI-PROJECT-23K24482
[Journal Article] 不妊症患者の漢方医学的背景と漢方薬の治療経験.2023
- Author(s)
  米澤理可，副田　翔，副田善勝，鮫島　梓，中川俊信，中島彰俊.
- Journal Title
  
  産婦人科漢方研究のあゆみ.
  
  Volume: 39 Pages: 128-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24482
[Journal Article] Dynamics of neuropilin1 (Nrp1)-positive thymus-derived and Nrp1-negative peripherally induced paternal antigen specific regulatory T cells in the uterus and spleen during pregnancy in mice.2023
- Author(s)
  Araishi K, Shima T, Yasuda I, Tsuda S, Morita K, Yamaki-Ushijima A, Nakashima A, Saito S
- Journal Title
  
  J Reprod Immunol
  
  Volume: 155 Pages: 103792-103792
- DOI
  10.1016/j.jri.2022.103792
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16764, KAKENHI-PROJECT-20K09614, KAKENHI-PROJECT-23K24482
[Journal Article] T cell immunity and the etiology and pathogenesis of preeclampsia2023
- Author(s)
  Saito Shigeru、Tsuda Sayaka、Nakashima Akitoshi
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: 159 Pages: 104125-104125
- DOI
  10.1016/j.jri.2023.104125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0287, KAKENHI-PROJECT-21K16764, KAKENHI-PROJECT-23K24482
[Journal Article] Gestational Age-Dependent Regulation of Transthyretin in Mice during Pregnancy2023
- Author(s)
  Cheng Shibin、Huang Zheping、Nakashima Akitoshi、Sharma Surendra
- Journal Title
  
  Biology
  
  Volume: 12 Issue: 8 Pages: 1048-1048
- DOI
  10.3390/biology12081048
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24482
[Journal Article] Silver nanoparticles suppress forskolin-induced syncytialization in BeWo cells2022
- Author(s)
  Sakahashi Yuji、Higashisaka Kazuma、Isaka Ryo、Izutani Rina、Seo Jiwon、Furuta Atsushi、Yamaki-Ushijima Akemi、Tsujino Hirofumi、Haga Yuya、Nakashima Akitoshi、Tsutsumi Yasuo
- Journal Title
  
  Nanotoxicology
  
  Volume: 16 Issue: 9-10 Pages: 883-894
- DOI
  10.1080/17435390.2022.2162994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24482
[Journal Article] オートファジー抑制と妊娠高血圧症候群発症の病態論2022
- Author(s)
  中島彰俊, 古田惇, 川口美保子
- Journal Title
  
  産科と婦人科
  
  Volume: 89 Pages: 162-168
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] The Autophagy-Lysosomal Machinery Enhances Cytotrophoblast?Syncytiotrophoblast Fusion Process2022
- Author(s)
  Furuta Atsushi、Shima Tomoko、Kawaguchi Mihoko、Yamaki-Ushijima Akemi、Yasuda Ippei、Tsuda Sayaka、Yoneda Satoshi、Higashisaka Kazuma、Cheng Shi-Bin、Matsumoto Kenji、Tsutsumi Yasuo、Sharma Surendra、Saito Shigeru、Nakashima Akitoshi
- Journal Title
  
  Reproductive Medicine
  
  Volume: 3 Issue: 2 Pages: 112-126
- DOI
  10.3390/reprodmed3020010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24482
[Journal Article] Hypoxia-Reoxygenation Impairs Autophagy-Lysosomal Machinery in Primary Human Trophoblasts Mimicking Placental Pathology of Early-Onset Preeclampsia2022
- Author(s)
  Cheng Shibin、Huang Zheping、Jash Sukanta、Wu Kathleen、Saito Shigeru、Nakashima Akitoshi、Sharma Surendra
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 10 Pages: 5644-5644
- DOI
  10.3390/ijms23105644
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24482
[Journal Article] Pregnancy depends on a delicate balance of immune activation and regulation2021
- Author(s)
  Saito Shigeru、Nakashima Akitoshi、Shima Tomoko、Tsuda Sayaka
- Journal Title
  
  Exploration of Immunology
  
  Volume: 1 Pages: 461-478
- DOI
  10.37349/ei.2021.00031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Preeclampsia complicated with maternal renal dysfunction is associated with poor neurological development at 3 years old in children born before 34 weeks of gestation.2021
- Author(s)
  Yoneda N, Yoneda S, Tsuda S, Ito M, Shiozaki A, Niimi H, Yoshida T, Saito S
- Journal Title
  
  Front. Pediatr.
  
  Volume: 1 Pages: 1-10
- DOI
  10.3389/fped.2021.624323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09663, KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-21K09535, KAKENHI-PROJECT-21K16764, KAKENHI-PROJECT-23K21403
[Journal Article] オートファジーと妊娠高血圧症候群2021
- Author(s)
  中島彰俊
- Journal Title
  
  日本産科婦人科学会雑誌
  
  Volume: 73 Pages: 1081-1088
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] ヒト胎盤形成と異常2021
- Author(s)
  中島彰俊, 古田惇
- Journal Title
  
  HORM FRONT GYNECOL
  
  Volume: 28 Pages: 187-192
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Novel blood test for early biomarkers of preeclampsia and Alzheimer’s disease2021
- Author(s)
  Cheng Shibin、Banerjee Sayani、Daiello Lori A.、Nakashima Akitoshi、Jash Sukanta、Huang Zheping、Drake Jonathan D.、Ernerudh Jan、Berg Goran、Padbury James、Saito Shigeru、Ott Brian R.、Sharma Surendra
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 15934-15934
- DOI
  10.1038/s41598-021-95611-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Molecular and immunological developments in placentas.2021
- Author(s)
  Nakashima A, Shima T, Aoki A, Kawaguchi M, Yasuda I, Tsuda S, Yoneda S, Yamaki-Ushijima A, Cheng SB, Sharma S, Saito S.
- Journal Title
  
  Hum Immunol.
  
  Volume: S0198-8859 Issue: 5 Pages: 00033-1
- DOI
  10.1016/j.humimm.2021.01.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-21K16764
[Journal Article] Aggrephagy Deficiency in the Placenta: A New Pathogenesis of Preeclampsia.2021
- Author(s)
  Nakashima A, Shima T, Tsuda S, Aoki A, Kawaguchi M, Furuta A, Yasuda I, Yoneda S, Yamaki-Ushijima A, Cheng SB, Sharma S, Saito S.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22 Issue: 5 Pages: 2432-2432
- DOI
  10.3390/ijms22052432
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-21K16764
[Journal Article] Etiological Value of Sterile Inflammation in Preeclampsia: Is It a Non-Infectious Pregnancy Complication?2021
- Author(s)
  Banerjee Sayani、Huang Zheping、Wang Zhengke、Nakashima Akitoshi、Saito Shigeru、Sharma Surendra、Cheng Shibin
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 11 Pages: 694298-694298
- DOI
  10.3389/fcimb.2021.694298
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] The role of decidual regulatory T cells in the induction and maintenance of fetal antigen-specific tolerance: Imbalance between regulatory and cytotoxic T cells in pregnancy complications.2021
- Author(s)
  Tsuda S, Nakashima A, Morita K, Shima T, Yoneda S, Kishi H, Saito S.
- Journal Title
  
  Hum Immunol.
  
  Volume: S0198-8859 Issue: 5 Pages: 00040-9
- DOI
  10.1016/j.humimm.2021.01.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-19K18690, KAKENHI-PROJECT-21K16764
[Journal Article] Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus2021
- Author(s)
  Tanaka T, Wada T, Uno K, Ogihara S, Ie H, Okekawa A, Ishikawa A, Ito T, Miyazawa Y, Sameshima A, Onogi Y, Tsuneki H, Sasahara M, Nakashima A, Saito S, Sasaoka T.
- Journal Title
  
  Diabetologia
  
  Volume: in press Issue: 7 Pages: 1660-1673
- DOI
  10.1007/s00125-021-05447-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08997, KAKENHI-PROJECT-19K09750, KAKENHI-PUBLICLY-19H05011, KAKENHI-PROJECT-21H02713
[Journal Article] Dynamic Changes in the Phenotype of Dendritic Cells in the Uterus and Uterine Draining Lymph Nodes After Coitus.2020
- Author(s)
  Yasuda I, Shima T, Moriya T, Ikebuchi R, Kusumoto Y, Ushijima A, Nakashima A, Tomura M, Saito S.
- Journal Title
  
  Front Immunol.
  
  Volume: 11 Pages: 557720-557720
- DOI
  10.3389/fimmu.2020.557720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-18K14598
[Journal Article] Disruption of placental homeostasis leads to preeclampsia.2020
- Author(s)
  Nakashima A, Shima T, Tsuda S, Aoki A, Kawaguchi M, Yoneda S, Yamaki-Ushijima A,Cheng SB, Sharma S, Saito S.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 9 Pages: 3298-3298
- DOI
  10.3390/ijms21093298
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Uterine CD11c+ cells induce the development of paternal antigen-specific Tregs via seminal plasma priming2020
- Author(s)
  Shima Tomoko、Nakashima Akitoshi、Yasuda Ippei、Ushijima Akemi、Inada Kumiko、Tsuda Sayaka、Yoshino Osamu、Tomura Michio、Saito Shigeru
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: - Pages: 103165-103165
- DOI
  10.1016/j.jri.2020.103165
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11221, KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-20K09614, KAKENHI-PROJECT-19K18690
[Journal Article] Analysis of TCR repertoire and PD-1 expression in decidual and peripheral CD8+ T cells reveals distinct immune mechanisms in miscarriage and preeclampsia.2020
- Author(s)
  Morita K, Tsuda S, Kobayashi E, Hamana H, Tsuda K, Shima T, Nakashima A, Ushijima A, Kishi H, Saito S.
- Journal Title
  
  Front Immunol.
  
  Volume: 11 Pages: 1082-1082
- DOI
  10.3389/fimmu.2020.01082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18K07321, KAKENHI-PROJECT-19K18690
[Journal Article] Placental autophagy failure: A risk factor for preeclampsia.2020
- Author(s)
  Nakashima A, Shima T, Aoki A, Kawaguchi M, Yasuda I, Tsuda S, Yoneda S, Yamaki-Ushijima A, Cheng SB, Sharma S, and Saito S.
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 46 Issue: 12 Pages: 2497-2504
- DOI
  10.1111/jog.14489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Bone morphogenetic protein‐2 enhances gonadotropin‐independent follicular development via sphingosine kinase 12020
- Author(s)
  Ito Masami、Yoshino Osamu、Ono Yosuke、Yamaki‐Ushijima Akemi、Tanaka Tomoko、Shima Tomoko、Orisaka Makoto、Iwase Akira、Nakashima Akitoshi、Saito Shigeru
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 85 Issue: 5
- DOI
  10.1111/aji.13374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09224, KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-19K09823
[Journal Article] CD206+ M2-like Macrophages are Essential for Successful Implantation.2020
- Author(s)
  Ono Y, Yoshino O, Ushijima A, Hiraoka T, Fukui Y, Nawaz A, Hirota Y, Wada S, Tobe K, Nakashima A, Osuga Y and Saito S.
- Journal Title
  
  Front Immunol.
  
  Volume: 11 Pages: 557184-557184
- DOI
  10.3389/fimmu.2020.557184
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-19H03144
[Journal Article] Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome2020
- Author(s)
  Kobayashi Mutsumi、Yoshino Osamu、Nakashima Akitoshi、Ito Masami、Nishio Kazuyuki、Ono Yosuke、Kusabiraki Tae、Kunitomi Chisato、Takahashi Nozomi、Harada Miyuki、Hattori Katsushige、Orisaka Makoto、Osuga Yutaka、Saito Shigeru
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 15 Pages: 110792-110792
- DOI
  10.1016/j.mce.2020.110792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-18K19600, KAKENHI-PROJECT-19K09823
[Journal Article] IFPA meeting 2018 workshop report II: Abnormally invasive placenta; inflammation and infection; preeclampsia; gestational trophoblastic disease and drug delivery2019
- Author(s)
  Albrecht Christian、Ichizuka Kiyotake、Nagamatsu Takeshi、Nakashima Akitoshi、Saito Shigeru、O'Tierney-Ginn Perrie
- Journal Title
  
  Placenta
  
  Volume: 18 Pages: 31200-1
- DOI
  10.1016/j.placenta.2019.02.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11082
[Journal Article] Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia2019
- Author(s)
  Nakashima Akitoshi、Cheng Shi-Bin、Ikawa Masahito、Yoshimori Tamotsu、Huber Warren J.、Menon Ramkumar、Huang Zheping、Fierce Jamie、Padbury James F.、Sadovsky Yoel、Saito Shigeru、Sharma Surendra
- Journal Title
  
  Autophagy
  
  Volume: 26 Issue: 10 Pages: 1-15
- DOI
  10.1080/15548627.2019.1707494
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-ORGANIZER-19H05749
[Journal Article] Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors2019
- Author(s)
  Cheng Shi-Bin、Nakashima Akitoshi、Huber Warren J.、Davis Sarah、Banerjee Sayani、Huang Zheping、Saito Shigeru、Sadovsky Yoel、Sharma Surendra
- Journal Title
  
  Cell Death & Disease
  
  Volume: 10 Issue: 12 Pages: 2342-2342
- DOI
  10.1038/s41419-019-2162-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts2019
- Author(s)
  Nakashima Akitoshi、Cheng Shi-Bin、Kusabiraki Tae、Motomura Kenichiro、Aoki Aiko、Ushijima Akemi、Ono Yosuke、Tsuda Sayaka、Shima Tomoko、Yoshino Osamu、Sago Haruhiko、Matsumoto Kenji、Sharma Surendra、Saito Shigeru
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 11466-11466
- DOI
  10.1038/s41598-019-47607-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Autophagy is a new protective mechanism against the cytotoxicity of platinum nanoparticles in human trophoblasts2019
- Author(s)
  Nakashima Akitoshi、Higashisaka Kazuma、Kusabiraki Tae、Aoki Aiko、Ushijima Akemi、Ono Yosuke、Tsuda Sayaka、Shima Tomoko、Yoshino Osamu、Nagano Kazuya、Yoshioka Yasuo、Tsutsumi Yasuo、Saito Shigeru
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 5478-5478
- DOI
  10.1038/s41598-019-41927-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] Current Understanding of Autophagy in Pregnancy2019
- Author(s)
  Nakashima Akitoshi、Tsuda Sayaka、Kusabiraki Tae、Aoki Aiko、Ushijima Akemi、Shima Tomoko、Cheng Shi-Bin、Sharma Surendra、Saito Shigeru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 9 Pages: 2342-2342
- DOI
  10.3390/ijms20092342
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Journal Article] CD11c+ M1-like macrophages (MΦs) but not CD206+ M2-like MΦ are involved in folliculogenesis in mice ovary2018
- Author(s)
  Ono Yosuke、Nagai Miwako、Yoshino Osamu、Koga Kaori、Nawaz Allah、Hatta Hideki、Nishizono Hirofumi、Izumi Gentaro、Nakashima Akitoshi、Imura Johji、Tobe Kazuyuki、Fujii Tomoyuki、Osuga Yutaka、Saito Shigeru
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8171-8171
- DOI
  10.1038/s41598-018-25837-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19600, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-16K11082, KAKENHI-PROJECT-16H05469
[Journal Article] Neutrophil Depletion Exacerbates Pregnancy Complications, Including Placental Damage, Induced by Silica Nanoparticles in Mice2018
- Author(s)
  Higashisaka Kazuma、Nakashima Akitoshi、Iwahara Yuki、Aoki Aiko、Nakayama Masahiro、Yanagihara Itaru、Lin Ying、Nagano Kazuya、Tsunoda Shin-ichi、Saito Shigeru、Yoshioka Yasuo、Tsutsumi Yasuo
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 1850-1850
- DOI
  10.3389/fimmu.2018.01850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26242055, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-16K11082
[Journal Article] Trophoblast-Specific Conditional Atg7 Knockout Mice Develop Gestational Hypertension2018
- Author(s)
  Aoki A, Nakashima A, Kusabiraki T, Ono Y, Yoshino O, Muto M, Kumasawa K, Yoshimori T, Ikawa M, Saito S
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 188 Issue: 11 Pages: 2474-2486
- DOI
  10.1016/j.ajpath.2018.07.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26251020, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-16K11082, KAKENHI-PROJECT-16K11086, KAKENHI-PROJECT-16K11087
[Journal Article] The role of autophagy in oocytogenesis, embryogenesis, implantation and pathophysiology of preeclampsia.2017
- Author(s)
  Nakashima A, Aoki A, Kusabiraki T, Shima T, Yoshino O, Shi-Bin Cheng, Sharma S, Saito S.
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 43 Issue: 4 Pages: 633-643
- DOI
  10.1111/jog.13292
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-16K11082
[Journal Article] Autophagy regulation in preeclampsia: Pros and cons.2017
- Author(s)
  2.Nakashima A, Aoki A, Kusabiraki T, Cheng SB, Sharma S, Saito S.
- Journal Title
  
  Journal of reproductive immunology
  
  Volume: 123 Pages: 17-23
- DOI
  10.1016/j.jri.2017.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11082
[Journal Article] Paternal antigen-specific proliferating regulatory T cells are increased in uterine-draining lymph nodes just before implantation and in pregnant uterus just after implantation by seminal plasma-priming in allogeneic mouse pregnancy.2015
- Author(s)
  Shima T, Inada K, Nakashima A, Ushijima A, Ito M, Yoshino O, Saito S.
- Journal Title
  
  J Reprod Immunol.
  
  Volume: 108 Pages: 78-82
- DOI
  10.1016/j.jri.2015.02.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390386, KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-26861316
[Journal Article] The frequency of peripheral blood CD4+ CD25high FoxP3+ andCD4+ CD25- FoxP3+ regulatory T cells in normal pregnancy and preeclampsia2012
- Author(s)
  Toldi G., Saito S, Shima T., HalmosA., Veresh Z., Vasarhelyi B., Rigo J., MolvarecA
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 68 Pages: 175-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791818
[Journal Article] The frequency of peripheral blood CD4+ CD25high FoxP3+ and CD4+ CD25- FoxP3+ regulatory T cells in normal pregnancy and preeclampsia.2012
- Author(s)
  Toldi G., Saito S., Shima T., Halmos A., Veresh Z., Vásárhelyi B., Rigó J., Molvarec A.
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 68 Issue: 2 Pages: 175-180
- DOI
  10.1111/j.1600-0897.2012.01145.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390386, KAKENHI-PROJECT-23791818
[Journal Article] The Balance of the Immune System between T Cells and NK Cells in Miscarriage2012
- Author(s)
  Nakashima A, Shima T, Inada K, Ito M, Saito S
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 67 Pages: 304-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791818
[Journal Article] Clinical implication of recent advances in our understanding of IL-17 and reproductive immunology2011
- Author(s)
  Saito S, Nakashima A, Ito M, Shima T
- Journal Title
  
  Expert Rev Clin Immunol
  
  Volume: 7 Pages: 649-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791818
[Journal Article] Peripheral blood galectin-1-expressing T and natural killer cells in normal pregnancy and preeclampsia2011
- Author(s)
  Molvarec A, Blois M S, Stenczer B, Toldi G, Tirado-Gonzalez I, ItoM, Shima T, Yoneda S, Vasarhelyi B, Rigo J., Saito S.
- Journal Title
  
  Clin. Immunol
  
  Volume: 139 Pages: 48-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791818
[Journal Article] Future directions of studies for recurrent miscarriage associated with immune etiologies2011
- Author(s)
  Saito S., Nakashima A., Shima T.
- Journal Title
  
  J Reprod Immunol
  
  Volume: 90 Pages: 91-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 卵巣がん治療のマラソン化～産婦人科医は良き伴走者となれるか～.2024
- Author(s)
  中島彰俊
- Organizer
  令和5年度岐阜産科婦人科研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] 胎盤形成におけるオートファジー～妊娠高血圧腎症の新規治療法開発を目指して～2024
- Author(s)
  中島彰俊, 古田　惇
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] オートファジー研究：基礎から臨床応用への取り組み.2023
- Author(s)
  中島彰俊
- Organizer
  第３８回日本生殖免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] 「癌治療の効果を享受するために」～数値で見えにくい症状と漢方薬～.2023
- Author(s)
  中島彰俊
- Organizer
  道北産婦人科医会11月学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] The Overexpression of Atg4B is a Novel Mechanism for Autophagy Inhibition in Preeclamptic Placentas.2023
- Author(s)
  Nakashima Akitoshi
- Organizer
  The Society for Reproductive Investigation 70th Annual Scientific Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] 妊娠高血圧症候群最近の話題～プレコンとフォローと治療開発と～.2023
- Author(s)
  中島彰俊
- Organizer
  第49回日本産婦人科医会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] 卵巣がん治療のマラソン化～産婦人科医は良き伴走者となれるか～.2023
- Author(s)
  中島彰俊
- Organizer
  三重婦人科腫瘍講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] 卵巣がん治療のマラソン化～産婦人科医は良き伴走者となれるか～2023
- Author(s)
  中島彰俊
- Organizer
  東北婦人科腫瘍研究会/第70回北日本産科婦人科学会学術総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] Autophagy抑制による妊娠高血圧症候群発症と治療法開発2023
- Author(s)
  中島彰俊，古田　惇，吉田美保子，山田清貴，布村晴香
- Organizer
  第68回日本生殖医学会学術講演会・総会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] 妊娠高血圧症候群最近の話題　～リスク評価、予防、そして治療はどうすべきか？～2023
- Author(s)
  中島彰俊
- Organizer
  第194回新潟産科婦人科集談会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] 胎盤から見た妊娠高血圧症候群～その発症とオートファジーの役割～.2022
- Author(s)
  中島　彰俊
- Organizer
  第92回三重県生涯教育特別研修セミナー.
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] プレコンセプションから始まる妊娠高血圧症候群~抗リン脂質抗体症候群や子宮形態異常から~.2022
- Author(s)
  中島　彰俊
- Organizer
  北陸産婦人科生殖内分泌フォーラム.
- Invited
- Data Source
  KAKENHI-PROJECT-23K24482
[Presentation] マウス異系妊娠において、末梢誘導性父親抗原特異的Treg細胞は母児境界面で増殖する2021
- Author(s)
  荒石康平　島友子
- Organizer
  第36回日本生殖免疫学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K09614
[Presentation] オートファジーと妊娠高血圧症候群 (Hypertensive disorders of pregnancy, HDP)2021
- Author(s)
  中島彰俊
- Organizer
  第73回日本産科婦人科学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] Can beta-galactosidase predict the autophagy failure in HDP placentas?2021
- Author(s)
  Nakashima A
- Organizer
  American society of reproductive immunology 2021 Virtual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] 妊娠高血圧症候群における胎盤形成不全~最新トピックスからオートファジーの関与まで.2021
- Author(s)
  中島彰俊
- Organizer
  第144回信州産婦人科連合会　学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] Symposium “Pathophysiology of PE (II)” The role of autophagy in pathophysiology of PE2021
- Author(s)
  Nakashima A
- Organizer
  The 22nd World Congress of International Society for the Study of Hypertension in Pregnancy.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] 抗リン脂質抗体症候群合併により発症リスクが高まる妊娠高血圧腎症ー新規診断法および治療法開発に向けてー.2020
- Author(s)
  中島彰俊
- Organizer
  福井県産婦人科医師連合第90回夏期臨床研修会プログラム
- Invited
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] 胎盤の恒常性維持をするオートファジーー妊娠高血圧腎症の解明へー．2020
- Author(s)
  中島彰俊
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] 胎盤形成におけるオートファジーの役割ー妊娠高血圧症候群との関与ー.2020
- Author(s)
  中島彰俊
- Organizer
  北陸産科婦人科学会
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] Disruption of collaboration between autophagy and lysosomes induces preeclampsia: comparative study between trophoblasts-specific Atg7 knockout-mediated poor placentation and human preeclamptic placentas2019
- Author(s)
  Akitoshi Nakashima
- Organizer
  International society for immunology of reproduction
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] Endoplasmic reticulum stress disrupts lysosomal homeostasis in human trophoblasts2019
- Author(s)
  Akitoshi Nakashima
- Organizer
  American society of reproductive immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] 血清中リソソーム測定による胎盤オートファジー機能低下検出法の確立2019
- Author(s)
  中島彰俊
- Organizer
  日本妊娠高血圧学会
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] リソソーム内酵素測定による胎盤オートファジー機能低下検出法の新規開発2019
- Author(s)
  中島彰俊
- Organizer
  日本胎盤学会
- Data Source
  KAKENHI-PROJECT-19K09750
[Presentation] The role of autophagy for pathophysiology of preeclampsia: Correlation between trophoblasts-specific Atg7 knockout mouse model and human preeclamptic placentas2018
- Author(s)
  AKITOSHI NAKASHIMA
- Organizer
  International Federation of Placenta Associations. Tokyo, Japan 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] The role of autophagy in pathophysiology of preeclampsia: Correlation between trophoblast-specific Atg7 knockout-mediated poor placentation and human preeclamptic placentas.2018
- Author(s)
  AKITOSHI　NAKASHIMA
- Organizer
  38th American-Sino joint meeting of reproductive immunology (ASRI-CSI 2018), Shanghai, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Trophoblast-specific Atg7 knockout-mediated poor placentation elicits hypertension, but not proteinuria2018
- Author(s)
  AKITOSHI NAKASHIMA
- Organizer
  38th American-Sino joint meeting of reproductive immunology. Shanghai, China.2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Autophagy is a new therapeutic target of preeclampsia: Trophoblasts-specific Atg7 knockout-mediated poor placentation induced hypertension in dams2018
- Author(s)
  AKITOSHI NAKASHIMA
- Organizer
  2018 Congress of the international society of Hypertension of pregnancy, Amsterdam, Netherland
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Impaired autophagy and transthyretin protein aggregation in preeclampsia2017
- Author(s)
  中島彰俊、草開妙、青木藍子、鮫島梓、島友子、吉野修、斎藤滋
- Organizer
  第69回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] オートファジー不全によるトランスサイレチン蓄積が胎盤機能不全に関与する2017
- Author(s)
  中島彰俊　草開妙　青木藍子　牛島明美　鮫島梓　島友子　吉野修　斎藤滋
- Organizer
  第22回日本プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] 早発妊娠高血圧症候群胎盤におけるオートファジー不全とトランスサイレチン蓄積の関与2017
- Author(s)
  中島彰俊,草開妙,青木藍子,牛島明美,鮫島梓,島友子,吉野修,Surendra Sharma,斎藤滋
- Organizer
  第25回日本胎盤学会
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] 妊娠高血圧腎症胎盤におけるオートファジー不全とトランスサイレチン蓄積の関与2017
- Author(s)
  中島彰俊,草開妙,青木藍子,牛島明美,鮫島梓,島友子,吉野修,Surendra Sharma,斎藤滋
- Organizer
  第32回日本生殖免疫学会
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Autophagy Inhibition leads to Transthyretin Overload and Aggregation in Human Trophoblasts and Hepatocytes: Novel Implications for Preeclampsia2017
- Author(s)
  Akitoshi Nakashima, Shi-Bin Cheng, Tae Kusabiraki, Aiko Aoki, Tomoko Shima, Osamu Yoshino, Surendra Sharma, Shigeru Saito.
- Organizer
  37th American society of reproductive immunology meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Preeclampsia (PE) serum disrupts the autophagy/lysosome pathway cooperated with endoplasmic reticulum (ER) stress.2016
- Author(s)
  Akitoshi Nakashima, Tomoko Shima, Aiko Aoki, Kumiko Inada, Satoshi Yoneda, Arihiro Shiozaki, Osamu Yoshino, Surendra Sharma, Shigeru Saito
- Organizer
  第68回日本産科婦人科学会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Paternal antigen specific-regulatory T cells are induced by tolerogeneic DCs after seminal plasma priming2016
- Author(s)
  Tomoko Shima, Kumiko Inada, Akemi Ushijima, Akitoshi Nakashima, Osamu Yoshino, Shigeru Saito
- Organizer
  13th Congress of the International Society for Immunology of Reproduction and the European Society for Reproductive Immunology
- Place of Presentation
  Erfurt、Germany
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861316
[Presentation] 妊娠高血圧腎症発症機序の解明に向けてーlysosome/ Autophagy経路から観た新たな概念2016
- Author(s)
  中島彰俊
- Organizer
  第52回周産期新生児学会
- Place of Presentation
  富山県富山市
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Preeclampsia serum disrupts the autophagy/lysosome pathway cooperated with endoplasmic reticulum (ER) stress2016
- Author(s)
  Akitoshi Nakashima
- Organizer
  10th INTERNATIONAL WORKSHOP in REUNION ISLAND
- Place of Presentation
  Reunion Island, France
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] 胎盤オートファジー抑制は妊娠高血圧症候群発症リスクである2016
- Author(s)
  中島彰俊
- Organizer
  第37回妊娠高血圧学会学術集会
- Place of Presentation
  埼玉県大宮市
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] Preeclampsia serum disrupts the autophagy/lysosome pathway via inhibiting nuclear translocation of transcription factor EB2016
- Author(s)
  Akitoshi Nakashima, Shi-Bin Cheng, Tomoko Shima, Surendra Sharma, Shigeru Saito.
- Organizer
  American society fo reproductive immunology
- Place of Presentation
  Baltimore, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] 妊娠高血圧腎症患者血清は小胞体ストレスと共に絨毛細胞のオートファジーを破綻させる2016
- Author(s)
  中島彰俊
- Organizer
  第24回日本胎盤学会学術集会
- Place of Presentation
  和歌山県和歌山市
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K11082
[Presentation] 精漿によるプライミングによる父親抗原特異的母児免疫寛容の誘導2015
- Author(s)
  島友子、稲田貢三子、牛島明美、伊藤実香、中島彰俊、吉野修、齋藤滋
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-26861316
[Presentation] Seminal fluid priming is important for inducing the paternal antigen-specific Tregs resulting in the successful implantation2012
- Author(s)
  島　友子
- Organizer
  13th International Symposium of Immunology of Reproduction (13th ISIR)
- Place of Presentation
  Varna, Bulgaria
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] Seminal fluid priming is important for inducing the paternal antigen-specific Tregs resulting inthe successful implantation2012
- Author(s)
  島友子
- Organizer
  13th International Symposium of Immunology of Reproduction(13th ISIR)、SpecialProf. Hans Donat Awward受賞
- Place of Presentation
  Varna, Bulgaria
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 精漿によるプライミングにより着床直前から子宮所属リンパ節には父親抗原特異的制御性T細胞が増加する2012
- Author(s)
  島友子
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] Paternal antigen-specific inducible regulatory T cells are increased just before the implantation by seminal fluid-priming2012
- Author(s)
  島友子
- Organizer
  the Joint International Congress of the American Society for Reproductive Immunology (ASRI) and the European Society forReproductive Immunology (ESRI)
- Place of Presentation
  Hamburg/Germany
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 制御性T細胞は精漿のプライミングにより子宮内に増加し、着床および初期の妊娠維持に重要な役割を果たす2012
- Author(s)
  島友子
- Organizer
  第26回日本生殖医学会学術講演会、シンポジウム
- Place of Presentation
  大阪医科大学
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 精漿によるプライミングにより着床直前から子宮所属リンパ節には父親抗原特異的制御性T細胞が増加する2012
- Author(s)
  島　友子
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] Paternal antigen-specific inducible regulatory T cells are increased just before the implantation by seminal fluid-priming2012
- Author(s)
  島　友子
- Organizer
  the Joint International Congress of the American Society for Reproductive Immunology (ASRI) and the European Society for Reproductive Immunology (ESRI)
- Place of Presentation
  Hamburg/Germany
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 精漿により誘導される父親抗原特異的制御性T細胞は着床期、妊娠初期に重要な役割を果たす2012
- Author(s)
  島　友子
- Organizer
  第27回日本生殖免疫学会総会学術集会
- Place of Presentation
  大阪医科大学
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 精漿によるプライミングにより着床直前から父親抗原特異的制御性T細胞が増加する2011
- Author(s)
  島　友子　稲田　貢三子　中島　彰俊　斎藤　滋
- Organizer
  第26回日本生殖免疫学会学術講演会
- Place of Presentation
  ウィンク愛知
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 制御性T細胞は精漿のプライミングにより子宮内に増加し、着床および初期の妊娠維持に重要な役割を果たす2011
- Author(s)
  島友子
- Organizer
  第26回日本生殖医学会学術講演会、シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-08
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 精漿によるプライミングにより着床直前から父親抗原特異的制御性T細胞が増加する2011
- Author(s)
  島友子
- Organizer
  第56回日本生殖免疫学会学術講演会
- Place of Presentation
  ウインク愛知
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 制御性T細胞は精漿のプライミングにより子宮内に増加し、着床および初期の妊娠維持に重要な役割を果たす2011
- Author(s)
  島　友子　　稲田　貢三子　　中島　彰俊　　齋藤　滋
- Organizer
  第56回日本生殖医学会学術講演会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23791818
[Presentation] 精漿によるプライミングによる父親抗原特異的母児免疫寛容の誘導
- Author(s)
  島友子、稲田　貢三子、牛島明美、伊藤実香、中島彰俊、吉野修、齋藤滋
- Organizer
  第67日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-26861316
[Presentation] 精漿によるプライミングは抑制性樹状細胞を誘導しトレランスを確立し妊娠成立に関与する
- Author(s)
  島友子、稲田貢三子、中島彰俊、吉野修、齋藤滋
- Organizer
  第66日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-26861316

1. Nakashima Akitoshi (00436792)

# of Collaborated Projects: 5 results

# of Collaborated Products: 70 results
2. 齋藤滋 (30175351)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 津田さやか (60839075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. 戸村道夫 (30314321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小池誠一 (10431686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Yoshioka Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. Nagano Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. Higashisaka Kazuma

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 斎藤滋

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
10. 仁井見英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 米田徳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 折坂誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 大須賀穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 角田慎一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 堤康央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉森保

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 笹岡利安

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 恒枝宏史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 和田努

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shima Tomoko 島 友子

SHIMA Tomoko 島 友子

Research Projects

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Co-Researchers

妊娠高血圧腎症におけるオートファジー不全と母児免疫寛容誘導メカニズムの解明Principal Investigator

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Failure of autophagy for the therapeutic target of preeclampsia

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the better understanding of the mechanism of maternal immune tolerance induction by regulatory T cells, dendritic cells, and NK cellsPrincipal Investigator

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New mechanism of autophagy inhibition from the study of preeclampsia

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The crosstalk of paternal antigen specific Treg cells and dendritic cells in feto-maternal tolerancePrincipal Investigator

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The development of new therapy for preeclampsia via modulation of autophagy

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The role of seminal fuid in paternal antigen specific feto-maternal tolerancePrincipal Investigator

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The importance of fetal antigen specific regulatory T cells in allogeneic pregnancyPrincipal Investigator

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[Book] Preeclampsia Basic, Genomic, and Clinical2018

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[Book] Preeclampsia Basic, Genomic, and Clinical2018

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[Journal Article] Immunological regulation and the role of autophagy in preeclampsia2024

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[Journal Article] The Role of Autophagy in the Female Reproduction System: For Beginners to Experts in This Field2023

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[Journal Article] 当科における卵巣癌の予後と維持化学療法の有効性の評価2023

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[Journal Article] Chloroquine is a safe autophagy inhibitor for sustaining the expression of antioxidant enzymes in trophoblasts.2023

Shima Tomoko 島友子

SHIMA Tomoko 島友子