SAKAMOTO Seisuke 阪本靖介

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SAKAMOTO SEISUKE 坂本靖介

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Researcher Number	00378689
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 臓器移植センター, センター長 2025: 京都府立医科大学, 医学(系)研究科(研究院), 講師
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人国立成育医療研究センター, 臓器移植センター, センター長 2017 – 2022: 国立研究開発法人国立成育医療研究センター, 臓器移植センター, 医長 2018: 国立研究開発法人国立成育医療研究センター, 臓器移植センター, 診療部長 2015 – 2016: 熊本大学, 医学部附属病院, 非常勤診療医師 2015: 熊本大学, 医学部附属病院, その他 … More 2015: 国立研究開発法人国立成育医療研究センター, その他部局等, その他 2014: 熊本大学, 医学部附属病院, 特任准教授 2014: 国立成育医療研究センター・臓器移植センター 2012 – 2014: 独立行政法人国立成育医療研究センター, その他部局等, その他 Less
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator Pediatrics / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related / Pediatric surgery
Keywords	Principal Investigator 外科 / 移植・再生医療 / 2光子励起レーザー顕微鏡 / ラット / 水素 / 水素水 / 虚血再灌流障害 / 肝移植 / レシピエント / ドナー / 分割肝移植 / 脳死臓器提供 … More Except Principal Investigator … More 小児肝移植 / 小児科学 / 肝移植 / 細胞外小胞 / 急性肝不全 / 集中治療医学 / liquid biopsy / cell free DNA / リキッドバイオプシー / 拒絶反応 / 一塩基多型 / 次世代シーケンサー / ドナー由来cell free DNA / 小腸移植 / 免疫学 / 移植・再生医療 / ウィルス / 感染床 / 感染症 / 分子生物学的診断 / ウイルス感染症 / EBウイルス / 肝線維化 / 細胆管増生 / Sox9遺伝子 / Notch Signal / ＳＯＸ９遺伝子 / 胆汁うったい / 葛西手術 / 細胆管反応 / SOX9遺伝子 / 胆道閉鎖症 / EBVウィルス / 細胞障害性T細胞活性 / 免疫抑制療法 / 低侵襲検査法 / EBウィルス Less

Clinical significance of microvesicles in acute liver injury in critically ill patients
- Principal Investigator
  
  若林健二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tokyo Medical and Dental University
The utility of donor derived cell free DNA to diagnose acute rejection in intestinal transplantation
- Principal Investigator
  
  Yamada Yohei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Keio University
Development of molecular biological diagnosis and treatment algorithm for persistent EB virus infection after pediatric liver transplantation
- Principal Investigator
  
  Fukuda Akinari
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Center for Child Health and Development
The efficacy of hidrogen-rich solution in ischemia-reperfusion injury and intravital imaging of neutrophil recruitment in liver transplantationPrincipal Investigator
- Principal Investigator
  
  Sakamoto Seisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Center for Child Health and Development
  Kumamoto University
The analysis of deceased donor split liver transplantation in JapanPrincipal Investigator
- Principal Investigator
  
  Sakamoto Seisuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Center for Child Health and Development
  Kumamoto University
SOX9 positive biphenotypic cell mediate ductular reaction with Notch signaling in Biliary atresia
- Principal Investigator
  
  Inomata Yukihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Kumamoto University
Development of detection of EBV infection and monitoring of immunosuppression by molecular analysis after pediatric liver trasplantation
- Principal Investigator
  
  FUKUDA Akinari
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Research Institute for Child Health and Development

All 2019 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 脳死からの臓器摘出（スタンダード小児外科手術）2013
- Author(s)
  阪本　靖介（監修：田口　智章、岩中　督）
- Total Pages
  387
- Publisher
  Medical View
- Data Source
  KAKENHI-PROJECT-25461968
[Journal Article] Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.2019
- Author(s)
  Uto K, Sakamoto S, Que W, Shimata K, Hashimoto S, Sakisaka M, Narita Y, Yoshii D, Zhong L, Komohara Y, Li XK, Inomata Y, Hibi T
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 19 Issue: 1 Pages: 25-25
- DOI
  10.1186/s12876-019-0939-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09411, KAKENHI-PROJECT-16K10432, KAKENHI-PROJECT-16K11349
[Journal Article] Evaluation of the Immune Function Assay in Pediatric Living Donor Liver Transplantation2015
- Author(s)
  Akinari Fukuda, Ken-Ichi Imadome, Seisuke Sakamoto, Takanobu Shigeta, Hajime Uchida, Masatoshi Matsunami, Kengo Sasaki, Hiroyuki Kanazawa, Fuyuko Kawano, Atsuko Nakazawa, Shigeyoshi Fujiwara, and Mureo Kasahara
- Journal Title
  
  Pediatric Transplantation
  
  Volume: 19(2) Issue: 2 Pages: 144-152
- DOI
  10.1111/petr.12402
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591593, KAKENHI-PROJECT-15K15116
[Journal Article] Current status of deceased donor split liver transplantation in Japan2015
- Author(s)
  Seisuke Sakamoto, Mureo Kasahara, Yasuhiro Ogura, Yukihiro Inomata, Shinji Uemoto
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 22 Issue: 12 Pages: 837-845
- DOI
  10.1002/jhbp.292
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461968
[Journal Article] 肝臓提供時の分割肝の適応と方法2014
- Author(s)
  阪本　靖介
- Journal Title
  
  今日の移植
  
  Volume: 27 Pages: 107-111
- Data Source
  KAKENHI-PROJECT-25461968
[Journal Article] Technical considerations of living donor hepatectomy of segment 2 grafts for infants.2014
- Author(s)
  Seisuke Sakamoto
- Journal Title
  
  Surgery
  
  Volume: 156 Issue: 5 Pages: 1232-1237
- DOI
  10.1016/j.surg.2014.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461968
[Journal Article] 本邦における小児脳死肝移植の課題と展望2014
- Author(s)
  阪本　靖介
- Journal Title
  
  今日の移植
  
  Volume: 27 Pages: 201-205
- Data Source
  KAKENHI-PROJECT-25461968
[Journal Article] 2度の臓器搬送を要し冷阻血時間が長時間となった脳死肝移植の1例2013
- Author(s)
  阪本　靖介
- Journal Title
  
  移植
  
  Volume: 48 Pages: 259-264
- NAID
  10031201200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461968
[Journal Article] Impact of the current organ allocation system for deceased donor liver transplantation on the outcomes of pediatric recipients: a single center experience in Japan2013
- Author(s)
  Seisuke Sakamoto
- Journal Title
  
  Pediatric Surgery International
  
  Volume: 29 Issue: 11 Pages: 1109-1114
- DOI
  10.1007/s00383-013-3381-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461968
[Journal Article] Effective control of Epstein-Barr virus infection following pediatric liver transplantation by monitoring of viral DNA load and lymphocyte surface markers2012
- Author(s)
  Imadome K, Fukuda A
- Journal Title
  
  Pediatric Transplantation
  
  Volume: 16(Epub ahead of print) Issue: 7 Pages: 748-757
- DOI
  10.1111/j.1399-3046.2012.01750.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591404, KAKENHI-PROJECT-22590374, KAKENHI-PROJECT-22590430, KAKENHI-PROJECT-23591375, KAKENHI-PROJECT-24591593
[Presentation] 肝・小腸移植後に発症した難治性EBV関連血球貪食リンパ組織球症の一例2019
- Author(s)
  山田全毅, 阪本靖介, 福田晃也, 石川百合子, 川野布由子, 内田孟, 清水誠一, 柳佑典, 武田昌寛, 坂本謙一, 加藤元博, 今留謙一, 笠原群生
- Organizer
  第55回日本移植学会
- Data Source
  KAKENHI-PROJECT-17K10134
[Presentation] Initial experience of deceased donor split liver transplantation in Japan2015
- Author(s)
  Seisuke Sakamoto
- Organizer
  14th Congress of the Asian Society of Transplantaion
- Place of Presentation
  Singapore
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461968
[Presentation] 小児生体肝移植後Epstein-Barr virus感染に対するアシクロビル予防投与の効果の検討2014
- Author(s)
  福田晃也，今留謙一，阪本靖介，佐々木健吾，内田　孟，濱野郁美，重田孝信，金澤寛之，中澤温子，笠原群生
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館，京都市
- Data Source
  KAKENHI-PROJECT-24591593
[Presentation] Prevention of Epstein-Barr virus infection after pediatric liver transplantation2013
- Author(s)
  Akinari Fukuda, Ken-ichi Imadome, Seisuke Sakamoto, Kengo Sasaki, Hajime Uchida, Ikumi Hamano, Takanobu Shigeta, Hiroyuki Kanazawa, Atsuko Nakazawa, Mureo Kasahara, Akira Matsui
- Organizer
  13th Asian Pan-Pacific Society for Pediatric Gastroenterology, Hepatology and Nutrition
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-24591593
[Presentation] 本邦における分割肝移植の現況と展望
- Author(s)
  阪本　靖介
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本（熊本）
- Year and Date
  2015-05-21 – 2015-05-22
- Data Source
  KAKENHI-PROJECT-25461968
[Presentation] 小児脳死肝移植の課題と展望
- Author(s)
  阪本　靖介
- Organizer
  第49回日本移植学会総会
- Place of Presentation
  国立京都国際会議場（京都）
- Data Source
  KAKENHI-PROJECT-25461968
[Presentation] 本邦における分割脳死肝移植症例の検討
- Author(s)
  阪本　靖介
- Organizer
  第33回日本肝移植研究会
- Place of Presentation
  ホテルオークラ神戸（神戸）
- Year and Date
  2015-05-28 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-25461968
[Presentation] 当院における脳死肝移植登録症例の検討
- Author(s)
  阪本　靖介
- Organizer
  第50回日本小児外科学会学術集会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25461968
[Presentation] 分割脳死肝移植症例の検討
- Author(s)
  阪本　靖介
- Organizer
  第31回日本肝移植研究会
- Place of Presentation
  熊本全日空ホテルニュースカイ（熊本）
- Data Source
  KAKENHI-PROJECT-25461968

1. KASAHARA Mureo (30324651)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. Inomata Yukihiro (50193628)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. FUKUDA Akinari (60455417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. IMADOME Ken-ichi (70392488)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. UMEZAWA Akihiro (70213486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Uemoto Shinji (40252449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Ogura Yasuhiro (20335251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. SUDA HIROKO (40632659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YOKOUCHI YUJI (60252227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Yamada Yohei (60383816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 梨井康 (60321890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 井ノ上逸朗 (00192500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 日比泰造 (10338072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 上野豪久 (10456957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松浦俊治 (10532856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 岡島英明 (20308604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 和田基 (80372291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 若林健二 (20723795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 馬場千晶 (00386195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YOSHII DAIKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Uto Keiichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKAMOTO Seisuke 阪本 靖介

SAKAMOTO SEISUKE 坂本 靖介

Research Projects

Research Products

Co-Researchers

Clinical significance of microvesicles in acute liver injury in critically ill patients

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The utility of donor derived cell free DNA to diagnose acute rejection in intestinal transplantation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of molecular biological diagnosis and treatment algorithm for persistent EB virus infection after pediatric liver transplantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The efficacy of hidrogen-rich solution in ischemia-reperfusion injury and intravital imaging of neutrophil recruitment in liver transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of deceased donor split liver transplantation in JapanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SOX9 positive biphenotypic cell mediate ductular reaction with Notch signaling in Biliary atresia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of detection of EBV infection and monitoring of immunosuppression by molecular analysis after pediatric liver trasplantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 脳死からの臓器摘出（スタンダード小児外科手術）2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of the Immune Function Assay in Pediatric Living Donor Liver Transplantation2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current status of deceased donor split liver transplantation in Japan2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肝臓提供時の分割肝の適応と方法2014

Author(s)

Journal Title

Data Source

[Journal Article] Technical considerations of living donor hepatectomy of segment 2 grafts for infants.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 本邦における小児脳死肝移植の課題と展望2014

Author(s)

Journal Title

Data Source

SAKAMOTO Seisuke 阪本靖介

SAKAMOTO SEISUKE 坂本靖介