Abe Yoshinori 阿部芳憲

… Alternative Names

阿部芳憲アベヨシノリ

ABE Yoshinori 阿部芳憲

安部芳憲アベヨシノリ

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Researcher Number	00386153
Other IDs	https://orcid.org/0000-0003-3894-494X
Affiliation (Current)	2025: 日本医科大学, 先端医学研究所, 助教 2025: 日本医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023: 日本医科大学, 先端医学研究所, 助教 2023: 日本医科大学, 研究部共同研究施設, 講師 2018 – 2021: 日本医科大学, 先端医学研究所, 助教 2017: 日本医科大学, 付置研究所, 助手 2013 – 2015: 日本医科大学, 付置研究所, 助教 … More 2009: 老人病研究所, 助教 2007 – 2009: 日本医科大学, 老人病研究所, 助教 2006: 日本医科大学, 老人病研究所, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 55020:Digestive surgery-related / General medical chemistry Except Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery / Biological Sciences
Keywords	Principal Investigator アルギニンメチル基転移酵素 / 膵癌 / PRMT5 / 癌幹細胞 / 膵臓癌 / 遺伝子転写制御 / 慢性炎症 / 非小細胞肺癌 / Hedgehogシグナル伝達経路 / 癌化の分子機構 … More / hedgehog経路 / 肺癌 / hedgehogシグナル伝達経路 / STAT3 … More Except Principal Investigator ケロイド / 組織幹細胞 / 幹細胞 / 空間的トランスクリプトーム解析 / PRMT5 / 遺伝子解析 / 遺伝子発現 / 治療薬 / 線維芽細胞 / ケロイド体質 / Hedgehogシグナル / 細胞周期制御 / Aurora-A / GLUT3 / 癌遺伝子 / 足場非依存性増殖 / β / Hedgehog signal / B / IKKα / NF-KB / Mdm2 / Hedeho sinal / Stat3 / IL-6 / 発癌 / P53 / O-GlcNAc修飾 / グルコーストランスポーター / NF-κB / グルコース代謝 / p53 / 癌抑制 / 癌化 Less

Analysis of arginine methylation signal network in pancreatic cancer to develop the novel cancer therapeutic strategyPrincipal Investigator
- Principal Investigator
  
  阿部芳憲
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nippon Medical School
空間的な遺伝子解析によるケロイド発生機序の解明と新規治療標的の導出
- Principal Investigator
  
  土佐眞美子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Nippon Medical School
Analysis of the mechanism of PRMT5-mediated pancreatic cancer stem cells maintenance, and development of therapeutic strategy targeting pancreatic cancer stem cells by PRMT5 inhibitionPrincipal Investigator
- Principal Investigator
  
  Abe Yoshinori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nippon Medical School
PRMT5による新たなケロイド幹細胞制御機構の解明と新治療薬開発への挑戦
- Principal Investigator
  
  土佐眞美子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Nippon Medical School
Elucidation of maintenance mechanism of mesenchymal stem cells in keloid to develop new therapy
- Principal Investigator
  
  Tosa Mamiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
The novel mechanisms of sonic hedgehog gene expression in the chronic inflammation induced cancerPrincipal Investigator
- Principal Investigator
  
  Abe Yoshinori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nippon Medical School
Analysis of the gene transcriptional network system regulated by nuclear tumor suppressive factors
- Principal Investigator
  
  TANAKA Nobuyuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nippon Medical School

All 2020 2019 2018 2013 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Interleukin 6 enhances glycolysis through expression of the glycolytic enzymes hexokinase2and6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-3.2010
- Author(s)
  Ando, M., Uehara, I., Kogure, K., Asano, Y., Nakajima, W., Abe, Y., Kawauchi, K., Tanaka, N.
- Journal Title
  
  J Nippon Med Sch 77
  
  Pages: 97-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054039
[Journal Article] Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.2008
- Author(s)
  Yoshinori Abe
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 105
  
  Pages: 4838-4843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054039
[Journal Article] Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.2008
- Author(s)
  Abe, Y., Oda-Sato, E., Tobiume, K., Kawauchi, K., Taya, Y., Okamoto, K., Oren, M., Tanaka, N.
- Journal Title
  
  Proc Natl Acad Sci U S A 105
  
  Pages: 4838-4843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] Hedgehog Signaling Pathway Maintains Mesenchymal Stem Cells in Keloid.2020
- Author(s)
  Mamiko Tosa, Y Abe, R Ogawa, N Tanaka
- Organizer
  The Meeting American Society of Plastic Surgery. 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] Hedgehog Signaling Pathway Maintains Mesenchymal Stem Cells in Keloid.2020
- Author(s)
  Mamiko Tosa, Y Abe, R Ogawa, N Tanaka
- Organizer
  The Meeting American Society of Plastic Surgery. 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09855
[Presentation] ケロイド真皮由来間葉系幹細胞に着目したケロイド発症機構の解明と治療への応用2019
- Author(s)
  土佐眞美子、阿部芳憲、田中信之、小川　令
- Organizer
  第27回日本形成外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] ケロイド新治療薬開発への挑戦2018
- Author(s)
  土佐眞美子、阿部芳憲、田中信之、小川　令
- Organizer
  第27回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] ケロイド新治療薬開発に向けたケロイド患者と健常人の真皮における遺伝子発現プロファイル解析2018
- Author(s)
  土佐眞美子、阿部芳憲、田中信之、小川　令
- Organizer
  第10回日本創傷外科学会
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] MEP50は転写因子Gli1の制御を介して非小細胞肺癌や胃癌において癌細胞の増殖だけでなく癌幹細胞様細胞の維持に関わる2013
- Author(s)
  阿部芳憲
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場　他
- Data Source
  KAKENHI-PROJECT-25870792
[Presentation] 癌化に関わる新規hedgehogシグナル伝達分子の解析2009
- Author(s)
  阿部芳憲
- Organizer
  第32会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] 癌化に関わる新規hedgehogシグナル伝達分子の解析.2009
- Author(s)
  阿部芳憲、鈴木陽輔、田中信之
- Organizer
  第32会日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] 癌化に関わる新しいhedgehog経路制御機構の解析第31回日本分子生物学会年会2008
- Author(s)
  阿部芳憲、鈴木陽輔、田中信之
- Organizer
  第81回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] 癌化に関わる新しいhedgehog経路制御機構の解析2008
- Author(s)
  阿部芳憲
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] The negative regulation of p53 by Hedgehog signaling.2007
- Author(s)
  Yoshinori Abe
- Organizer
  EMBO WORKSHOP 2007, Molecular Mechanisms of Cell Cycle Control in Normal & Malignant Cells
- Place of Presentation
  Spetses Island, Greece
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] Role of NF-κB for cellular transformation in p53 deficient cells.2007
- Author(s)
  阿部芳憲
- Organizer
  第30回分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] Negatve regulation of p53 by Hedgehog signaling.2007
- Author(s)
  Abe, Y., Oda-Sato, E., Tobiume, K., Kawauchi, K., Tanaka, N.
- Organizer
  EMBO WORKSHOP 2007, Molecular Mechanisms of Cell Cycle Control in Normal & Malignant Cells
- Place of Presentation
  Spetses Island, Greece
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] STAT3とアルギニンメチル基転移酵素PRMT5を介した新しい肺癌幹細胞様細胞の維持機構
- Author(s)
  阿部芳憲
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25870792

1. Tosa Mamiko (30301568)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. TANAKA Nobuyuki (80222115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. UEHARA Ikuno (50434139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. NAKAJIMA Wataru (40557500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SATO Eri (90339440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KAWAUTI Keiko (40434138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. TOBIUME Kei (40350037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Abe Yoshinori 阿部 芳憲

阿部 芳憲 アベ ヨシノリ

ABE Yoshinori 阿部 芳憲

安部 芳憲 アベ ヨシノリ

Research Projects

Research Products

Co-Researchers

Analysis of arginine methylation signal network in pancreatic cancer to develop the novel cancer therapeutic strategyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

空間的な遺伝子解析によるケロイド発生機序の解明と新規治療標的の導出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the mechanism of PRMT5-mediated pancreatic cancer stem cells maintenance, and development of therapeutic strategy targeting pancreatic cancer stem cells by PRMT5 inhibitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PRMT5による新たなケロイド幹細胞制御機構の解明と新治療薬開発への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of maintenance mechanism of mesenchymal stem cells in keloid to develop new therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The novel mechanisms of sonic hedgehog gene expression in the chronic inflammation induced cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the gene transcriptional network system regulated by nuclear tumor suppressive factors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Interleukin 6 enhances glycolysis through expression of the glycolytic enzymes hexokinase2and6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-3.2010

Author(s)

Journal Title

Data Source

[Journal Article] Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.2008

Author(s)

Journal Title

Data Source

[Journal Article] Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.2008

Author(s)

Journal Title

Data Source

[Presentation] Hedgehog Signaling Pathway Maintains Mesenchymal Stem Cells in Keloid.2020

Author(s)

Organizer

Data Source

[Presentation] Hedgehog Signaling Pathway Maintains Mesenchymal Stem Cells in Keloid.2020

Author(s)

Organizer

Data Source

[Presentation] ケロイド真皮由来間葉系幹細胞に着目したケロイド発症機構の解明と治療への応用2019

Author(s)

Organizer

Data Source

[Presentation] ケロイド新治療薬開発への挑戦2018

Author(s)

Organizer

Data Source

[Presentation] ケロイド新治療薬開発に向けたケロイド患者と健常人の真皮における遺伝子発現プロファイル解析2018

Author(s)

Organizer

Abe Yoshinori 阿部芳憲

阿部芳憲アベヨシノリ

ABE Yoshinori 阿部芳憲

安部芳憲アベヨシノリ