Shimozawa Togo 下澤東吾

… Alternative Names

SHIMOZAWA Togo 下澤東吾

下澤東吾シモザワトウゴ

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Researcher Number	00386608
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院理学系研究科(理学部), 技術専門職員
Affiliation (based on the past Project Information) *help	2017: 東京大学, 理学部技術部, 技術専門職員 2015 – 2016: 早稲田大学, 理工学術院, 助教 2014: 早稲田大学, 生命理工学部, 助教 2008: The University of Tokyo, 大学院・理学系研究科, 特任研究員 2007: Tohoku University, 先進医工学研究機構, 助教 2006: 早稲田大学, 理工学術院, 助手
Review Section/Research Field	Principal Investigator Biophysics / Biological Sciences / Biophysics/Chemical physics Except Principal Investigator Biomedical engineering/Biomaterial science and engineering / General physiology
Keywords	Principal Investigator 蛍光イメージング / アクチンフィラメント / 蛍光タンパク質 / 細胞骨格 / 細胞接着 / αカテニン / BiFCプローブ / 多量体形成 / タンパク質動態 / カテニン / 細胞間接着 / 力学刺激応答 / 力学応答 … More Except Principal Investigator … More ナノイメージング / サルコメア / in vivoイメージング / 拡張性心筋症 / カルシウムイオン / 心筋収縮 / 心筋 / 心筋症 / 熱 / 心筋細胞 / 熱パルス / in vivo / 細胞運動・形態形成・細胞間相互作用 / 生体ナノイメージング / 生体運動・形態形成・細胞間相互作用 / 微小管 Less

Verification of the force-dependent binding of an alpha-catenin to an actn filamentPrincipal Investigator
- Principal Investigator
  
  Shimozawa Togo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Waseda University
Development of basic technologies for the treatment of heart disease by infra-red laser irradiation.
- Principal Investigator
  
  Kobirumaki-Shimozawa Fuyu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Jikei University School of Medicine
Analysis of cell dynamics using intravital nano-imaging.
- Principal Investigator
  
  FUYU Kobirumaki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
新規な張力レポーター分子の作製と細胞内における力の時空間分布の観察Principal Investigator
- Principal Investigator
  
  下澤東吾
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Tohoku University
力学的負荷でアクチンフィラメントは機能変調を受けるか-顕微操作による実験的研究-Principal Investigator
- Principal Investigator
  
  下澤東吾
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics/Chemical physics
- Research Institution
  Tohoku University
  Waseda University

All 2018 2017 2016 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] LC-MS/MS and chiroptical spectroscopic analyses of multidimensional metabolic systems of chiral thalidomide and its derivatives.2017
- Author(s)
  Ogino, Y., M. Tanaka, T. Shimozawa, and T. Asahi
- Journal Title
  
  Chirality
  
  Volume: - Issue: 6 Pages: 1-12
- DOI
  10.1002/chir.22683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21444
[Journal Article] In vivo cardiac nano-imaging: A new technology for high-precision analyses of sarcomere dynamics in the heart2017
- Author(s)
  Togo Shimozawa, Erisa Hirokawa, Fuyu Kobirumaki-Shimozawa, Kotaro Oyama, Seine A. Shintani, Takako Terui, Yasuharu Kushida, Seiichi Tsukamoto, Teruyuki Fujii, Shin'ichi Ishiwata, and Norio Fukuda
- Journal Title
  
  Prog. Biophys. Mol. Biol.
  
  Volume: 124 Pages: 31-40
- DOI
  10.1016/j.pbiomolbio.2016.09.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04677, KAKENHI-PROJECT-15J07373, KAKENHI-PROJECT-15J10205, KAKENHI-PROJECT-15K21444, KAKENHI-PROJECT-15K12524, KAKENHI-PROJECT-26560225, KAKENHI-PROJECT-16K18993
[Journal Article] Dynamic properties of bio-motile systems as a liquid-crystalline structure2017
- Author(s)
  Shin'ichi Ishiwata, Makito Miyazaki, Katsuhiko Sato, Koutaro Nakagome, Seine A. Shintani, Fuyu Kobirumaki-Shimozawa, Norio Fukuda, Kazuya Suzuki, Jun Takagi, Yuta Shimamoto, and Takeshi Itabashi
- Journal Title
  
  Mol. Cryst. Liq. Cryst.
  
  Volume: 印刷中 Issue: 1 Pages: 127-150
- DOI
  10.1080/15421406.2017.1289445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26400441, KAKENHI-PROJECT-17K15102, KAKENHI-PROJECT-15H04677, KAKENHI-PROJECT-17H02939, KAKENHI-PROJECT-15J07373, KAKENHI-PROJECT-15K12524, KAKENHI-PROJECT-26560225
[Journal Article] Nano-imaging of the beating mouse heart in vivo: Importance of sarcomere dynamics, as opposed to sarcomere length per se, in the regulation of cardiac function.2016
- Author(s)
  Kobirumaki-Shimozawa F, Oyama K, Shimozawa T, Mizuno A, Ohki T, Terui T, Minamisawa S, Ishiwata S, Fukuda N
- Journal Title
  
  Journal of General Physiology
  
  Volume: 147 Issue: 1 Pages: 53-62
- DOI
  10.1085/jgp.201511484
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12524, KAKENHI-PROJECT-26560225, KAKENHI-PROJECT-15K21444, KAKENHI-PLANNED-23107003, KAKENHI-PROJECT-15H04677, KAKENHI-PROJECT-15J10205, KAKENHI-PROJECT-16K15184
[Journal Article] Simultaneous imaging of local calcium and single sarcomere length in rat neonatal cardiomyocytes using yellow Cameleon-Nano1402016
- Author(s)
  Seiichi Tsukamoto, Teruyuki Fujii, Kotaro Oyama, Seine A. Shintani, Togo Shimozawa, Fuyu Kobirumaki-Shimozawa, Shin’ichi Ishiwata, and Norio Fukuda
- Journal Title
  
  J. Gen. Physiol.
  
  Volume: 148 Issue: 4 Pages: 341-355
- DOI
  10.1085/jgp.201611604
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04677, KAKENHI-PROJECT-15J07373, KAKENHI-PROJECT-15J10205, KAKENHI-PROJECT-15K21444, KAKENHI-PROJECT-15K12524, KAKENHI-PROJECT-26560225
[Journal Article] Cardiac thin filament regulation and the Frank-Starling mechanism.2014
- Author(s)
  Kobirumaki-Shimozawa F, Inoue T, Shintani SA, Oyama K, Terui T, Minamisawa S, Ishiwata S, Fukuda N.
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: Ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659116
[Journal Article] Sarcomere length nanometry in rat neonatal cardiomyocytes expressed with α-actinin-AcGFP in Z-discs2014
- Author(s)
  Shintani, S., Oyama, K., Kobirumaki, F., Shimozawa, F., Ohki, T., Ishiwata, S., and Fukuda, N.
- Journal Title
  
  J. Gen. Physiol.
  
  Volume: 143 Issue: 4 Pages: 513-524
- DOI
  10.1085/jgp.201311118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000011, KAKENHI-PROJECT-22227005, KAKENHI-PLANNED-23107003, KAKENHI-PROJECT-23300146, KAKENHI-PROJECT-23650274, KAKENHI-PROJECT-23659116, KAKENHI-PROJECT-24650213, KAKENHI-PROJECT-26560225
[Journal Article] Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ΔK2102013
- Author(s)
  Inoue T, Kobirumaki-Shimozawa F, Kagemoto T, Fujii T, Terui T, Kusakari Y, Hongo K, Morimoto S, Ohtsuki I, Hashimoto K, Fukuda N
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 63 Pages: 69-78
- DOI
  10.1016/j.yjmcc.2013.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107003, KAKENHI-PROJECT-23300146, KAKENHI-PROJECT-23650274, KAKENHI-PROJECT-23659116, KAKENHI-PUBLICLY-25136719
[Journal Article] Sarcomere imaging by quantum dots for the study of cardiac muscle physiology.2012
- Author(s)
  Fuyu Kobirumaki-Shimozawa, Kotaro Oyama, Takahiro Serizawa, Akari Mizuno, Tatsuya Kagemoto, Togo Shimozawa, Shin'ichi Ishiwata, Satoshi Kurihara and Norio Fukuda
- Journal Title
  
  Journal of Biomedicine and Biotechnology
  
  Volume: Vol. 2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659116
[Journal Article] Mechanical Distortion of Single Actin Filaments Induced by External Force : Detection by Fluorescence Imaging2009
- Author(s)
  Shimozawa T. and Ishiwata S.
- Journal Title
  
  Biophys. J. 96(3)
  
  Pages: 1036-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19037025
[Journal Article] 光によう生物システムの操作と計測 : 1分子と細胞2008
- Author(s)
  石渡信一、小口祐伴、Sergey V. Mikhailenko、大木高志、下澤東吾、大山廣太郎、鈴木団
- Journal Title
  
  Microoptics News 26(3)
  
  Pages: 55-60
- Data Source
  KAKENHI-PROJECT-19037025
[Journal Article] How load and the nucleotide state affect the actin filament binding mode of the molecular motor myosin V2008
- Author(s)
  Mikhailenko S. V., Oguchi Y., Ohki T., Shimozawa T. Olivares A.O., De La Cruz E. M . and Ishiwata S.
- Journal Title
  
  J. Korean Phys. Soc. 53
  
  Pages: 1726-1730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19037025
[Journal Article] Size Distribution of Linear and Helical Polymers in Actin Solution Analyzed by Photon Counting Histogram2007
- Author(s)
  Terada N, Shimozawa T, Ishiwata S, Funatsu T
- Journal Title
  
  Biophys J. 92(6)
  
  Pages: 2162-2171
- Data Source
  KAKENHI-PROJECT-18740263
[Presentation] In vivo analysis of individual sarcomere dynamics in the beating mouse heart.2018
- Author(s)
  小比類巻生, 大山廣太郎, 下澤東吾, 石渡信一, 福田紀男
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K12524
[Presentation] Equilibrium of two fluorescence states in the UnaG-Bilirubin Complex2017
- Author(s)
  Yoh SHITASHIMA, Togo SHIMOZAWA, Toru ASAHI
- Organizer
  Biophysical society 61st Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2017-02-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21444
[Presentation] 2種類の蛍光強度を示す蛍光タンパク質UnaGの蛍光特性の解析2017
- Author(s)
  下島洋、下澤東吾、朝日透
- Organizer
  第97回日本化学会春季年会
- Place of Presentation
  横浜市
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K21444
[Presentation] In vivoナノイメージングによる心筋収縮の可視化と熱による制御2016
- Author(s)
  大山廣太郎, 小比類巻生, 下澤東吾, 福田紀男
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター,　北海道
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K12524
[Presentation] 蛍光特性を用いたビリルビン依存型蛍光タンパク質UnaGの自己二量化の解析2016
- Author(s)
  下島洋、下澤東吾、石田みやび、朝日透
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  京都
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K21444
[Presentation] High-speed, high-performance real-time imaging of physiological sarcomere dynamics in the beating heart in vivo.2016
- Author(s)
  Kobirumaki-Shimozawa, Kotaro Oyama, Togo Shimozawa, Takako Terui, Shin'ichi Ishiwata, Norio Fukuda
- Organizer
  Biophysical Society 60th Annual Meeting
- Place of Presentation
  Los Angels, California, USA
- Year and Date
  2016-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12524
[Presentation] SIMULTANEOUS HIGH-PRECISION IMAGING OF LOCAL CALCIUM AND SINGLE SARCOMERE LENGTH IN RAT NEONATAL CARDIOMYOCYTES VIA EXPRESSION OF YELLOW CAMELEON-NANO140 IN Z-DISCS.2016
- Author(s)
  Seiichi Taukamoto, Kotaro Oyama, Teruyuki Fujii, Fuyu Kobirumaki-Shimozawa, Seine A. Shintani, Shin'ichi Ishiwata, Norio Fukuda
- Organizer
  Biophysical Society 60th Annual Meeting
- Place of Presentation
  Los Angels, California, USA
- Year and Date
  2016-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12524
[Presentation] ビリルビンを発色団とする蛍光タンパク質UnaGのキロオプティカル特性2015
- Author(s)
  下澤東吾、下島洋、石田みやび、朝日透
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15K21444
[Presentation] Chiroptical Properties of Bilirubin-Dependent Fluorescent Protein UnaG2015
- Author(s)
  Yoh Shitashima,Togo Shimozawa, Miyabi Ishida, Toru Asahi
- Organizer
  Symposium on Molecular Chirality 2015
- Place of Presentation
  東京
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K21444
[Presentation] Chiroptical Properties of the Bilirubin Compounded with Fluorescent Protein UnaG in vitro2015
- Author(s)
  Yoh Shitashima,Togo Shimozawa, Miyabi Ishida, Toru Asahi
- Organizer
  Pacifichem 2015
- Place of Presentation
  ハワイ
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21444
[Presentation] 高速ライブイメージングを用いたin vivo単一サルコメア計測2014
- Author(s)
  小比類巻生, 大山廣太郎, 広川恵里沙, 下澤東吾, 照井貴子, 南沢享, 石渡信一, 福田紀男
- Organizer
  第９１回日本生物物理学会大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23659116
[Presentation] Real-time imaging of sarcomere dynamics in the mouse heart in vivo2014
- Author(s)
  Fuyu Kobirumaki-Shimozawa, Kotaro Oyama, Akari Mizuno, Takako Terui, Togo Shimozawa, Takeshi Ohki, Susumu Minamisawa, Shin'ichi Ishiwata, Norio Fukuda
- Organizer
  Biophysical Society 58th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23659116
[Presentation] Real-time high-resolution cardiac imaging in vivo2013
- Author(s)
  小比類巻生, 大山廣太郎, 新谷正嶺, 広川恵里沙, 下澤東吾, 照井貴子, 石渡信一, 福田紀男
- Organizer
  第５１回日本生物物理学会年会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-23659116
[Presentation] 生きたマウスの心臓における単一サルコメア長解析2013
- Author(s)
  小比類巻生，大山廣太郎，照井貴子，水野紅理，影本達也，下澤東吾，石渡信一，福田紀男
- Organizer
  第11回ナノ学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659116
[Presentation] α-Actinin-GFPを用いたアダルト心筋細胞のサルコメア長計測2011
- Author(s)
  小比類巻生, 照井貴子, 水野紅理, 影本達也, 下澤東吾, 石渡信一, 栗原敏, 福田紀男
- Organizer
  ナノ学会
- Place of Presentation
  北海道大学学術交流会館
- Data Source
  KAKENHI-PROJECT-23659116
[Presentation] Real-time measurement of sarcomere length in the rodent heart by using α-Actinin-GFP2011
- Author(s)
  Fuyu Kobirumaki, Takako Terui, Akari Mizuno, Tatsuya Kagemoto, Togo Shimozawa, Shin'ichi Ishiwata, Norio Fukuda
- Organizer
  日本生物物理学会
- Place of Presentation
  兵庫県立大学・姫路書写キャンパス
- Data Source
  KAKENHI-PROJECT-23659116
[Presentation] Mechanical Distortion of Single Actin Filaments Induced by External Force2009
- Author(s)
  Togo SHIMOZAWA and Shin'ichi ISHIWATA
- Organizer
  第1回定量生物学会
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-19037025
[Presentation] Mechanical Distortion of Single Actin Filaments Induced by External Force2008
- Author(s)
  Togo SHIMOZAWA and Shin'ichi ISHIWATA
- Organizer
  2^<nd> Int. Symposium of on Bio-Nanosystems
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-19037025
[Presentation] ナノスケール高速ライブイメージングによるマウスin vivoサルコメア計測
- Author(s)
  小比類巻生, 大山廣太郎, 下澤東吾, 照井貴子, 南沢享, 石渡信一, 福田紀男
- Organizer
  第12回ナノ学会大会
- Place of Presentation
  京都
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-23659116

1. FUYU Kobirumaki (40548905)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. FUKUDA Norio (30301534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. OTSUKI Iwao (70009992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TERUI Takako (10366247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. HIGUCHI Hideo (90165093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OYAMA Kotaro (70632131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. 大木高志 (80443480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. SATO Katsuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SHIMA Shin-ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. NAKAGOME Koutaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 石渡信一

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 本郷賢一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 草刈洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 橋本和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimozawa Togo 下澤 東吾

SHIMOZAWA Togo 下澤 東吾

下澤 東吾 シモザワ トウゴ

Research Projects

Research Products

Co-Researchers

Verification of the force-dependent binding of an alpha-catenin to an actn filamentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of basic technologies for the treatment of heart disease by infra-red laser irradiation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cell dynamics using intravital nano-imaging.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規な張力レポーター分子の作製と細胞内における力の時空間分布の観察Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

力学的負荷でアクチンフィラメントは機能変調を受けるか-顕微操作による実験的研究-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] LC-MS/MS and chiroptical spectroscopic analyses of multidimensional metabolic systems of chiral thalidomide and its derivatives.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo cardiac nano-imaging: A new technology for high-precision analyses of sarcomere dynamics in the heart2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic properties of bio-motile systems as a liquid-crystalline structure2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nano-imaging of the beating mouse heart in vivo: Importance of sarcomere dynamics, as opposed to sarcomere length per se, in the regulation of cardiac function.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous imaging of local calcium and single sarcomere length in rat neonatal cardiomyocytes using yellow Cameleon-Nano1402016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cardiac thin filament regulation and the Frank-Starling mechanism.2014

Author(s)

Journal Title

Data Source

[Journal Article] Sarcomere length nanometry in rat neonatal cardiomyocytes expressed with α-actinin-AcGFP in Z-discs2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ΔK2102013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sarcomere imaging by quantum dots for the study of cardiac muscle physiology.2012

Author(s)

Journal Title

Data Source

[Journal Article] Mechanical Distortion of Single Actin Filaments Induced by External Force : Detection by Fluorescence Imaging2009

Shimozawa Togo 下澤東吾

SHIMOZAWA Togo 下澤東吾

下澤東吾シモザワトウゴ

[Presentation] 蛍光特性を用いたビリルビン依存型蛍光タンパク質UnaGの自己二量化の解析2016