KOBORI Akio 小堀哲生

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Kobori Akio 小堀哲生

KOBORI AKIO 小堀哲生

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Researcher Number	00397605
Other IDs
Affiliation (Current)	2025: 京都工芸繊維大学, 分子化学系, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 京都工芸繊維大学, 分子化学系, 教授 2016: 京都工芸繊維大学, 分子化学系, 准教授 2015: 京都工芸繊維大学, その他部局等, 准教授 2014: 京都工芸繊維大学, 工芸科学研究科, 准教授 2010 – 2011: 京都工芸繊維大学, 工芸科学研究科, 准教授 … More 2008: 京都工芸繊維大学, 工芸科学研究科, 准教授 2007: Kyoto Institute of Technology, 工芸科学研究科, 助教 2006: 京都工芸繊維大学, 工芸科学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Chemistry related to living body / Bio-related chemistry / Science and Engineering Except Principal Investigator Basic Section 90120:Biomaterials-related / Chemistry related to living body
Keywords	Principal Investigator DNA / RNA / エクソソーム / バイオマーカー / ラマン散乱 / SERS / 核酸プローブ / アミロイドβ / アプタマー / 架橋性核酸 … More / ジアジリン / RNaseH / 光反応 / 核酸医薬 / アンチセンス / イメージング / 核酸 / 表面増強ラマン散乱 / エピジェネティクス / miRNA / 変異原性 / 酸化損傷塩基 / クロスリンク / 過酸化脂質 / エテノアデノシン / アンチセンス核酸 / ナフチリジン / SNPs … More Except Principal Investigator ナノファイバー / ペプチド / ドラッグデリバリーシステム / ペプチド医薬 / ナノテクノロジー / 超分子 / 超分子ポリマー / 超分子重合 / ナノ材料 / 自己組織化 / 蛍光プローブ / トランスクリプトーム / RNAプローブ / 細胞・組織 / 核酸 / 遺伝子 / バイオテクノロジー Less

スプリットアプタマーを利用したエクソソーム定量システムの開発Principal Investigator
- Principal Investigator
  
  小堀哲生
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto Institute of Technology
細胞膜内滞留型ペプチドナノファイバーの開発とペプチド医薬デリバリーへの応用
- Principal Investigator
  
  和久友則
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kyoto Institute of Technology
Development of ANCsome contaning aASO-RNaseH conjugatesPrincipal Investigator
- Principal Investigator
  
  KOBORI AKIO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto Institute of Technology
Direct cytoplasmic delivery of protein drugs by electric field-driven cell membrane-permeable peptide nanoneedles
- Principal Investigator
  
  Waku Tomonori
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kyoto Institute of Technology
Development of quantitative SERS and their applicationsPrincipal Investigator
- Principal Investigator
  
  Kobori Akio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto Institute of Technology
Development of life-survey methods using SERS probesPrincipal Investigator
- Principal Investigator
  
  KOBORI AKIO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Kyoto Institute of Technology
Development of the recognition motif of DNA oxidation and its application to comprehensive analysis of DNA mutation.Principal Investigator
- Principal Investigator
  
  KOBORI Akio
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto Institute of Technology
Developments of in situ real-time monitoring system by fluorescent-probe and regulation protocols of functional RNAs
- Principal Investigator
  
  MURAKAMI Akira
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto Institute of Technology
新規蛍光プローブを用いたRNA検出法の開発Principal Investigator
- Principal Investigator
  
  小堀哲生
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto Institute of Technology
架橋型アンチセンス核酸による転写活性制御法の開発Principal Investigator
- Principal Investigator
  
  小堀哲生
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto Institute of Technology

[Book] Curr. Protoc. Nucleic acid Chem.2014
- Author(s)
  A. Kobori; A. Yamayoshi; Akira Murakami.
- Total Pages
  15
- Publisher
  Wiley and Sons. Inc.
- Data Source
  KAKENHI-PROJECT-26410179
[Journal Article] Oligonucleotide-based telomerase inhibitors with a photoresponsive α-chloroaldehyde2025
- Author(s)
  Kobata Kentaro、Matsubara Kazuki、Nishikawa Risa、Narita Yuki、Matsuo Kazuya、Waku Tomonori、Kobori Akio
- Journal Title
  
  Bioorganic Medicinal Chemistry Letters
  
  Volume: 120 Pages: 130138-130138
- DOI
  10.1016/j.bmcl.2025.130138
- Data Source
  KAKENHI-PROJECT-24K08635
[Journal Article] Ratiometric sandwich-type assays for RNAs with a point mutation using benzo[a]pyrene-modified probes2024
- Author(s)
  Watari Yu、Nakatani Kaito、Kobata Kentaro、Matsuo Kazuya、Waku Tomonori、Kobori Akio
- Journal Title
  
  Chemical Communications
  
  Volume: 60 Issue: 59 Pages: 7610-7613
- DOI
  10.1039/d4cc02188f
- Data Source
  KAKENHI-PROJECT-24K08635
[Journal Article] A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions2024
- Author(s)
  Matsuo Kazuya、Ogawa Honoka、Yamaoka Shusuke、Waku Tomonori、Kobori Akio
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 111 Pages: 129892-129892
- DOI
  10.1016/j.bmcl.2024.129892
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24H01315, KAKENHI-PROJECT-24K08634, KAKENHI-PROJECT-24K08635
[Journal Article] Photo-cross-linking reactions in RNA?DNA heteroduplexes using photoreactive DNA incorporated with diazirine and aryl azide warheads2024
- Author(s)
  Matsuo Kazuya、Kitamura Machiko、Kobata Kentaro、Unita Daiki、Waku Tomonori、Kobori Akio
- Journal Title
  
  Chemistry Letters
  
  Volume: 53 Issue: 8 Pages: 152-152
- DOI
  10.1093/chemle/upae152
- Data Source
  KAKENHI-PROJECT-24K08635
[Journal Article] Wash-free FISH of bacterial ribosomal RNAs by benzo[a]pyrene-modified oligonucleotides.2024
- Author(s)
  Y. Watari, K. Nakatani, K. Matsuo, T. Waku, A. Kobori
- Journal Title
  
  Results in Chemistry
  
  Volume: 7 Pages: 101214-101214
- DOI
  10.1016/j.rechem.2023.101214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05307, KAKENHI-PUBLICLY-22H04750, KAKENHI-PUBLICLY-22H05566, KAKENHI-PROJECT-24K08635
[Journal Article] Sandwich-typed detection of nucleic acids by bioorthogonal SERS probes2021
- Author(s)
  R. Ota, N. Takagi, Y. Imaizumi, T. Waku, A. Kobori
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 40 Pages: 166-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05354
[Journal Article] Ratiometric SERS Assays for Reliable and Automatic Quantification of Nucleic Acids2021
- Author(s)
  Ota Ryo、Fukushima Yuki、Araki Yuta、Sasaki Kenta、Waku Tomonori、Kobori Akio
- Journal Title
  
  Chemistry Letters
  
  Volume: 50 Issue: 3 Pages: 513-517
- DOI
  10.1246/cl.200798
- NAID
  130007995508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05354
[Journal Article] Inhibition of Amyloid β Fibrillation by Nanoparticles Composed of Ovalbumin-derived Amphiphilic Peptides2020
- Author(s)
  Waku Tomonori、Kobayashi Yukako、Wada Mei、Hamawaki Taiga、Handa Akihiro、Okuda Michiaki、Sugimoto Hachiro、Kobori Akio、Tanaka Naoki
- Journal Title
  
  Chemistry Letters
  
  Volume: 49 Issue: 4 Pages: 383-385
- DOI
  10.1246/cl.200048
- NAID
  130007828855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12800
[Journal Article] Investigation on the interactions between self-assembled β-sheet peptide nanofibers and model cell membranes2020
- Author(s)
  Waku T., Kasai A., Kobori A., Tanaka N.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 24 Pages: 9518-9518
- DOI
  10.3390/ijms21249518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12800
[Journal Article] Selective cross-linking behavior of oligodeoxyribonucleotides containing 2'-O-[N-(4,5',8-trimethylpsoralen-4'- ylmethylcarbamoyl)]adenosine to mutant H-ras DNA2019
- Author(s)
  A.Yamayoshi, M.Higuchi, Y.Sakai, A.Kobori, T.Yamamoto, T. Shibata, A. Murakami
- Journal Title
  
  NUCLEOSIDES, NUCLEOTIDES AND NUCLEIC ACIDS
  
  Volume: 39 Issue: 1-3 Pages: 119-130
- DOI
  10.1080/15257770.2019.1677912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05354, KAKENHI-PROJECT-18H02087, KAKENHI-PROJECT-20K05561
[Journal Article] Photochromic DNA having fluorescent protein-inspired nucleosides2018
- Author(s)
  Akio Kobori, Taichiro Arai, Yuya Sakata, Takayuki Sugita, Asako Yamayoshi, Akira Murakami
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 59 Issue: 41 Pages: 3690-3693
- DOI
  10.1016/j.tetlet.2018.08.064
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02087, KAKENHI-PROJECT-18K05354
[Journal Article] Inhibition effect of photoresponsive α-haloaldehyde-conjugated oligonucleotides on the gene expression in HeLa cells stably expressing GFP2017
- Author(s)
  Sugihara, Yuta; NAKATA, YUKI; Yamayoshi, Asako; Murakami, Akira; Kobori, Akio
- Journal Title
  
  chemistry letters
  
  Volume: 46 Issue: 8 Pages: 1265-1268
- DOI
  10.1246/cl.170298
- NAID
  130005907030
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410179, KAKENHI-PROJECT-15K05564
[Journal Article] Characterization of the Releasing Profile of MicroRNA from RISC Using Anti-miRNA Oligonucleotides2017
- Author(s)
  Jumpei Ariyoshi, Nao Eimori, Akio Kobori, Akira Murakami, Hiroshi Sugiyama, Asako Yamayoshi
- Journal Title
  
  chemistry letters
  
  Volume: 46 Issue: 1 Pages: 143-145
- DOI
  10.1246/cl.160895
- NAID
  130005308315
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410179, KAKENHI-PROJECT-15K05564
[Journal Article] Development of Novel Photoresponsive Oligodeoxyribonucleotides with a 2'-O-Diazirine-conjugated Adenosine for DNA Interstrand Crosslinking2017
- Author(s)
  Yuta Sugihara, Soichi Tatsumi, Akio Kobori
- Journal Title
  
  chemistry letters
  
  Volume: 46 Issue: 2 Pages: 236-239
- DOI
  10.1246/cl.160998
- NAID
  130005317075
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410179
[Journal Article] Cross-Linking Antisense Oligodeoxyribonucleotides with a Photoresponsive α-Chloroaldehyde Moiety for RNA Point Mutations2016
- Author(s)
  Sugihara Y., Nakata Y., Yamayoshi A., Murakami A., Kobori A.
- Journal Title
  
  J Org Chem
  
  Volume: 81 Issue: 3 Pages: 981-986
- DOI
  10.1021/acs.joc.5b02573
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K05564, KAKENHI-PROJECT-26410179
[Journal Article] Development of Novel Antisense Oligonucleotides for the Functional Regulation2015
- Author(s)
  Ariyoshi, J., Momokawa, D., Eimori, N., Kobori, A., Murakami A., Yamayoshi, A.
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 26 Issue: 12 Pages: 2454-2460
- DOI
  10.1021/acs.bioconjchem.5b00501
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K05564, KAKENHI-PROJECT-26410179
[Journal Article] Functional regulation of RNA-induced silencing complex by photoreactive oligonucleotides2014
- Author(s)
  Matsuyama, Y., Yamayoshi, A.*, Kobori, A., Murakami A.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 22 Issue: 3 Pages: 1003-1007
- DOI
  10.1016/j.bmc.2013.12.044
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24550186, KAKENHI-PROJECT-25620132, KAKENHI-PROJECT-26410179
[Journal Article] Novel photodynamic effect of psoralen-conjugated oligonucleotides for discrimination of methylation of cytosine in DNA2014
- Author(s)
  Yamayoshi, A.*, Matsuyama, Y., Kushida, M., Kobori, A., Murakami A.
- Journal Title
  
  Photochemistry and Photobiology
  
  Volume: 90 Issue: 3 Pages: 716-722
- DOI
  10.1111/php.12232
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24550186, KAKENHI-PROJECT-25620132, KAKENHI-PROJECT-26410179
[Journal Article] Surprising Repair Activities of Nonpolar Analogs of 8-oxoG Expose Features of Recognition and Catalysis by Base Excision Repair Glycosylases2012
- Author(s)
  P. L. McKibbin, A. Kobori, Y. Taniguchi, E. T. Kool, S. S. David
- Journal Title
  
  Journal of The American Chemical Society
  
  Volume: 134 Issue: 3 Pages: 1653-1661
- DOI
  10.1021/ja208510m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750154
[Journal Article] Development of a system to sensitively and specifically visualize-fos mRNA in living cells using bispyrene-modified RNA probes.2011
- Author(s)
  Waki R., Yamayoshi A., Kobori A., Murakami A.
- Journal Title
  
  Chemical Communications
  
  Volume: 47 Pages: 4204-4206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750154
[Journal Article] Development of a system to sensitively and specifically visualize-fos mRNA in living cells using bispyrene-modified RNA probes2011
- Author(s)
  Waki R., Yamayoshi A., Kobori A., Murakami A.
- Journal Title
  
  Chemical Communications
  
  Volume: 47 Issue: 14 Pages: 4204-4206
- DOI
  10.1039/c0cc04639f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750154
[Journal Article] Real-time Imaging of RNA Expression in Living Cells Using Bispyrene-modified RNA Probes2011
- Author(s)
  Waki R., Yamayoshi A., Kobori A., Murakami A.
- Journal Title
  
  Chemistry letters
  
  Volume: 40 Pages: 1247-1248
- NAID
  10030220013
- URL
  http://dx.doi.org/10.1246/cl.2011.1247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750154
[Journal Article] Specific regulation of point-mutated K-ras-immortalized cell proliferation by a photo-dynamic antisense strategy2010
- Author(s)
  Higuchi M., Yamayoshi A., Kato K., Kobori A., Wake N., Murakami A.
- Journal Title
  
  Oligonucleotides
  
  Volume: 20 Issue: 1 Pages: 37-44
- DOI
  10.1089/oli.2008.0173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750154
[Journal Article] Specific regulation of point-mutated K-ras-immortalized cell proliferation by a photo-dynamic antisense strategy.2010
- Author(s)
  Higuchi M., Yamayoshi A., Kato K., Kobori A., Wake N., Murakami A.
- Journal Title
  
  Oligonucleotides
  
  Volume: 20 Pages: 37-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750154
[Journal Article] Synthesis and Photo-induced Cross-linking Reactions of 4, 5', 8-Trimethylpsoralen-incorporated Oligodeoxyribonucleotide.2009
- Author(s)
  A. Kobori, et al.
- Journal Title
  
  Chemistry Letters 38
  
  Pages: 272-273
- NAID
  10025120271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550164
[Journal Article] Synthesis of antisense oligo-nucleotides containing2'-O-psoralenyl-methoxyalkyl adenosine for photodynamic regulation of point mutations in RNA2009
- Author(s)
  Higuchi M., Kobori A., Yamayoshi A., Murakami A.
- Journal Title
  
  Bioorganic & Medicinal chemistry 17
  
  Pages: 475-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550164
[Journal Article] Synthesis and Photo-inducCross-linking Reactions of 4,5', 8-Trimethyl-c-fosprobe核細胞質ピレン法によるガン細胞中のc-fos-mRNAのリアルタイムイメージング例(疑似カラー)psoralen-incorporated Oligodeoxyribonucleotide2009
- Author(s)
  Kobori A., Takaya T., Higuchi M., Yamayoshi A, Murakami A
- Journal Title
  
  Chemistry lett. 38
  
  Pages: 272-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550164
[Journal Article] Naphthyridine-tethered Oligodeoxyribonucleotides: Dye/DNA conjugatesfor Homogeneous SNPs Assays2008
- Author(s)
  Akio Kobori
- Journal Title
  
  Chemistry Letters 37
  
  Pages: 354-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550164
[Journal Article] Microarray-based label-free detection of RNAusing bispyrene-modified 2'-O-methyloligo-ribonucleotide as capture and detection probe2008
- Author(s)
  Sakamoto T., Kobori A., Murakami A.
- Journal Title
  
  Bioorganic & Medicinal chemistry Letters 18
  
  Pages: 2590-2593
- NAID
  120001856660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550164
[Journal Article] Microarray-based label-free detection of RNA using bispyrene-modified 2'-O-methyl oligoribonucleotide as capture and detection probe.2008
- Author(s)
  T., Sakamoto・A., Kobori・A., Murakami
- Journal Title
  
  Bioorg Med Chem Lett. 18
  
  Pages: 2590-2593
- NAID
  120001856660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18750147
[Journal Article] Naphthyridine-tethered Oligodeoxyribo-nucleotides : Dye/DNA conjugates for Homogeneous SNPs Assays2008
- Author(s)
  Kobori A., Mori T., Ubayashi M., MurakamiA.
- Journal Title
  
  Chem. Lett. 37
  
  Pages: 354-355
- NAID
  10021078903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550164
[Journal Article] Naphthyridine-tethered Oligonucleotides: Dye/DNA Conjugates for SNPs Assays2008
- Author(s)
  A., Kobori・T., Mori・M., Ubayashi・A., Murakami
- Journal Title
  
  Chemistry Letters 37
  
  Pages: 354-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18750147
[Journal Article] Synthesis of naphthyridine-conjugated DNA probes and their application to SNPs typing.2008
- Author(s)
  A., Kobori・T., Mori・M., Ubayashi・A., Murakami.
- Journal Title
  
  Nucleic Acids Symp Ser 51
  
  Pages: 309-310
- Data Source
  KAKENHI-PROJECT-18750147
[Journal Article] Various properties of polymeric carriers improved the transfection efficiency2007
- Author(s)
  T.Hashimoto, A.Mahara, A.Kobori, A.Murakami, T.Yamaoka
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 333-334
- Data Source
  KAKENHI-PROJECT-18038027
[Journal Article] Solid-phase detection of RNA using bispyrene-modified RNA probe2007
- Author(s)
  T.Sakamoto, A.Kobori, A.Murakami
- Journal Title
  
  Nucleic acids symp. ser. 50
  
  Pages: 215-216
- Data Source
  KAKENHI-PROJECT-18750147
[Journal Article] Various properties of polymeric carriers improved the transfection efficiency2007
- Author(s)
  T.Hashimoto, A.Mahara, A.Kobori, A.Murakami, T.Yamaoka
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 333-334
- Data Source
  KAKENHI-PROJECT-18750147
[Journal Article] Solid-phase detection of RNA using bispyrene-modified RNA probe2007
- Author(s)
  T.Sakamoto, A.Kobori, A.Murakami
- Journal Title
  
  Nucleic acids symp. ser. 50
  
  Pages: 215-216
- Data Source
  KAKENHI-PROJECT-18038027
[Journal Article] Synthesis and cross-linking activities of oligodeoxynucleotides containing a 4-oxoalkenal group.2007
- Author(s)
  A.Kobori, T.Kobuchi, M.Ikeda, A.Murakami
- Journal Title
  
  Nucleic acids symp. ser. 50
  
  Pages: 59-60
- Data Source
  KAKENHI-PROJECT-18750147
[Journal Article] Detection of L-DNA-tagged PCR products by surface plasmon resonance imaging.2007
- Author(s)
  G.Hayashi, M.Hagihara, A.Kobori, K.Nakatani
- Journal Title
  
  ChemBioChem 8
  
  Pages: 169-171
- Data Source
  KAKENHI-PROJECT-18750147
[Journal Article] Homogeneous fluorescence assays for RNA-diagnosis by pyrene-conjugated 2'-O-methyloligoribonucleo-tides2007
- Author(s)
  Sakamoto T., Kobori A., Shigesawa M., Amitani Y., Higuchi M., Murakami A
- Journal Title
  
  Nucleosides, Nucleotides, & Nucleic Acids 26
  
  Pages: 1659-1664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550164
[Journal Article] Detection of L-DNA-tagged PCR products by surface plasmon resonance imaging.2007
- Author(s)
  G.Hayashi, M.Hagihara, A.Kobori, K.Nakatani.
- Journal Title
  
  ChemBioChem 8
  
  Pages: 169-171
- Data Source
  KAKENHI-PROJECT-18038027
[Journal Article] Synthesis and cross-linking activities of oligodeoxynucleotides containing a 4-oxoalkenal group.2007
- Author(s)
  A.Kobori, T.Kobuchi, M.Ikeda, A.Murakami
- Journal Title
  
  Nucleic acids symp. ser. 50
  
  Pages: 59-60
- Data Source
  KAKENHI-PROJECT-18038027
[Journal Article] Evaluation of mismatch-binding ligands as inhibitors for Rev-RRE interaction.2006
- Author(s)
  K.Nakatani, S.Horie, Y.Goto, A.Kobori, S.Hagihara.
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry 14
  
  Pages: 5384-5388
- Data Source
  KAKENHI-PROJECT-18038027
[Journal Article] Evaluation of mismatch-binding ligands as inhibitors for Rev-RRE interaction.2006
- Author(s)
  K.Nakatani, S.Horie, Y.Goto, A.Kobori, S.Hagihara
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry 14
  
  Pages: 5384-5388
- Data Source
  KAKENHI-PROJECT-18750147
[Presentation] 点変異を標的としたジアジリン修飾光架橋性核酸の開発2023
- Author(s)
  宇仁田　大樹、小畑健太郎、松原一稀、松尾和哉、和久友則、小堀哲生
- Organizer
  日本化学会第103回春季年会
- Data Source
  KAKENHI-PROJECT-21K05307
[Presentation] Construction of DNA-RNase H conjugates using photo-cross-linking ODNs2023
- Author(s)
  Kentaro Kobata, Kazuya Matsuo, Tomonori Waku, Akio Kobori
- Organizer
  ISNAC2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05307
[Presentation] ジアジリン残基を導入した光架橋性拡散によるテロメラーゼ活性阻害2022
- Author(s)
  松原一稀、辰巳颯一、松尾和哉、和久友則、小堀哲生
- Organizer
  日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K05307
[Presentation] Reactivity of photo-cross-linking ODNs in cellular extracts2022
- Author(s)
  小畑健太郎、松原一稀、松尾和哉、和久友則、小堀哲生
- Organizer
  ISNAC2022
- Data Source
  KAKENHI-PROJECT-21K05307
[Presentation] 細胞抽出液中における光架橋性核酸の反応性2022
- Author(s)
  松原一稀、松尾和哉、和久友則、小堀哲生
- Organizer
  第12回4大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-21K05307
[Presentation] 光応答性α-ハロアルデヒドを鎖中に導入したアンチセンス核酸の開発と架橋特性評価2021
- Author(s)
  小畑健太郎、Ivana dvorakova、太田良、辰巳颯一、和久友則、小堀哲生
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-21K05307
[Presentation] 点変異mRNA選択的な遺伝子発現抑制を志向した光応答性α-ブロモアルデヒド修飾核酸の開発2021
- Author(s)
  小畑健太郎、Ivana dvorakova、太田良、辰巳颯一、和久友則、小堀哲生
- Organizer
  第15回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K05307
[Presentation] 線維長の制御されたペプチドナノファイバーの精密作製と抗原デリバリーキャリアへの応用2019
- Author(s)
  西山魁人・和久友則・小堀哲生・田中直毅
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-19K12800
[Presentation] ペプチドナノファイバーの線維長精密制御と抗原デリバリーキャリアへの応用2019
- Author(s)
  西山魁人・和久友則・小堀哲生・田中直毅
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19K12800
[Presentation] 線維長の制御されたペプチドナノファイバーの精密作製と抗原デリバリーキャリアへの応用2019
- Author(s)
  和久友則・小枝清花・小堀哲生・田中直毅
- Organizer
  第41回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-19K12800
[Presentation] 卵殻膜ペプチドを修飾した電界紡糸 PVA ナノファイバーの作製と細胞培養基板への応用2019
- Author(s)
  吉川貴士・和久友則・小堀哲生・田中直毅
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19K12800
[Presentation] 抗原を担持した細胞内環境応答性ペプチドナノファイバーの作製と機能評価2019
- Author(s)
  横山知沙・和久友則・小堀哲生・田中直毅
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-19K12800
[Presentation] Design of Intracellular Environment-responsive Peptide Nanofibers for Antigen Delivery2019
- Author(s)
  Tomonori Waku・Akio Kobori・Naoki Tanaka
- Organizer
  5th International Symposium on Advances in Sustainable Polymers
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12800
[Presentation] 抗原を担持した細胞内環境応答性ペプチドナノファイバーの設計と機能評価2019
- Author(s)
  横山知沙・和久友則・小堀哲生・田中直毅
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19K12800
[Presentation] 生体直行型ラマンタグを鎖中に導入した核酸の合成と機能評価2018
- Author(s)
  太田良、福島雄基、小堀哲生
- Organizer
  第１２回バイオ関連化学合同シンポジウム
- Data Source
  KAKENHI-PROJECT-18K05354
[Presentation] PEG-核酸複合体を導入した金ナノロッドの調製と機能評価2018
- Author(s)
  福島雄基、太田良、小堀哲生
- Organizer
  日本バイオマテリアル学会第１３回関西若手研究発表会
- Data Source
  KAKENHI-PROJECT-18K05354
[Presentation] Development of a sandwich-typed assay for nucleic acids using surface-enhanced Raman scattering2018
- Author(s)
  Ryo Ota, Akio Kobori
- Organizer
  256th ACS national meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05354
[Presentation] Facile quantification of miRNAs in biological samples2018
- Author(s)
  Kizuki Ichimi, Yu Watari, Akio Kobori
- Organizer
  2018ISNAC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05354
[Presentation] 生体直行型SERSプローブの開発と標的核酸検出への応用2017
- Author(s)
  太田良、髙木紀志、永井悠貴、杉原悠太、小堀哲生
- Organizer
  日本化学会春季年会
- Place of Presentation
  慶応大学
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] リキッドバイオプシーを志向した体液中miRNA測定2017
- Author(s)
  小堀哲生
- Organizer
  ケミカルバイオロジーmini-symposium at KIT
- Place of Presentation
  京都工芸繊維大学
- Invited
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] Development of a novel drug delivery system for targeting microRNA2016
- Author(s)
  ○KISHIMOTO, Yusuke, TAMURA, Rie, MURAMATSU, Chie, KOBORI, Akio, ASHIHARA, Eishi, MURAKAMI, Akira YAMAYOSHI, Asako
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学　京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] ケージドαハロアルデヒド基を持つ架橋性アンチセンス核酸の細胞内活性評価2016
- Author(s)
  杉原悠太, 中田有紀, 山吉麻子, 村上章, 小堀哲生
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学　京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] Development of a miRNA diagnostic system with LNA-conjugated solid supports and PMUpy2 probes2016
- Author(s)
  Y.Sugihra, K. Nakajima, Y.Watari, J.Ariyoshi,A.Yamayoshi, A.Murakami, A.Kobori
- Organizer
  ISNAC2016
- Place of Presentation
  熊本大学
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] ピレン修飾核酸プローブを用いたmiRNA検出システムの開2016
- Author(s)
  中嶋　康介, 西村　茜, 山吉麻子, 村上章, 小堀哲生
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学　京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] Photo-cross-linking oligonucleotides: toward regulation of target gene expression2016
- Author(s)
  A.Kobori
- Organizer
  THE 14th VIETNAM&JAPAN INTERNATIONAL JOINT SEMINAR
- Place of Presentation
  ハノイ工科大学
- Year and Date
  2016-09-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] Development of a novel system for evaluation of binding affinities between RISC and antisense oligonucleotides2016
- Author(s)
  ○KONISHI, Ryo, ARIYOSHI, Jumpei, MATSUYAMA, Yohei, NAKAMURA, Hiromi1, KOBORI, Akio, MURAKAMI, Akira YAMAYOSHI, Asako
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学　京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] イミダゾロン誘導体を塩基部にもつフォトクロミック核酸の合成と機能評価2016
- Author(s)
  杉田　貴之,中村　一喜, 新井　太一郎, 山吉麻子, 村上章, 小堀哲生
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学　京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] RISC機能の制御を目指した遺伝子発現制御素子の開発(Ⅳ)アンチセンス核酸の化学構造がRISCからのmicroRNA解離効果に与える影響2016
- Author(s)
  有吉純平, 栄森奈緒, 小西諒, 小堀哲生, 村上章, 山吉麻子
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学　京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] ピレンプローブを用いたサンドイッチ型microRNA検出法2016
- Author(s)
  中嶋康介、渡優有、杉原悠太、有吉純平、山吉麻子、村上章、小堀哲生
- Organizer
  日本核酸医薬学会第2回年会
- Place of Presentation
  東京理科大学
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] Development of novel RISC inhibitors for promoting release of microRNA from RISC (II) The effects of chemical modifications of oligonucleotides on releasing of microRNA from RISC2015
- Author(s)
  有吉純平,栄森奈緒, 小西諒, 小堀哲生, 村上章, 山吉麻子
- Organizer
  The 42nd International Synposium on Nucleic Acids Chemistry 2015 (ISNAC2015)
- Place of Presentation
  イーグレひめじ
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] HEXIM1たんぱく質に対して特異的結合能を有する新規転写抑制剤の開発2015
- Author(s)
  吉本航大，岸本恭介，小堀哲生, 村上章, 山吉麻子
- Organizer
  第一回日本核酸医薬学会
- Place of Presentation
  京都テルサ
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] イミダゾロン誘導体が導入されたフォトクロミック核酸塩基の合成と機能評価2015
- Author(s)
  杉田貴之・新井太一朗1・坂田優也・中村一喜・山吉麻子・村上章・小堀哲生
- Organizer
  第45回　複素環化学討論会
- Place of Presentation
  早稲田大学国際会議場
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] Regulation of translational activity of EGFP mRNA using photoresponsive α-haloaldehyde-conjugated ORNs2015
- Author(s)
  Yuki Nakata1, Yuta Sugihara, Akio Kobori, Asako Yamayoshi, Akira Murakami
- Organizer
  THE INTERNATIONAL CHEMICAL CONGRESS OF ACIFIC BASIN SOCIETIES 2015
- Place of Presentation
  Hawaii Convention Center
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] 人工核酸によるnon-codingRNAの機能制御(Ⅴ) microRNAを標的とした機能性核酸の設計指針2015
- Author(s)
  有吉純平,栄森奈緒, 小西諒, 小堀哲生, 村上章, 山吉麻子
- Organizer
  第25回　バイオ・高分子シンポジウム
- Place of Presentation
  東京工業大学大岡山キャンパス
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] RISC活性の制御を目指した機能性核酸の開発(II)アンチセンス核酸(ASO)の化学構造がRISCからのmicroRNAの解離に与える影響2015
- Author(s)
  有吉純平, 小西諒, 栄森奈緒, 小堀哲生, 村上章, 山吉麻子
- Organizer
  第一回日本核酸医薬学会
- Place of Presentation
  京都テルサ
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] イミダゾロン誘導体が導入されたフォトクロミック核酸の合成と機能評価2015
- Author(s)
  杉田貴之・中村一喜・山吉麻子・村上章・小堀哲生
- Organizer
  4大学連携研究フォーラム
- Place of Presentation
  京都工芸繊維大学　60週年記念館　記念ホール
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] Novel inhibitors targeting microRNA: Peptide-oligonucleotide conjugates for promotional releasing of microRNA from RISC2015
- Author(s)
  Jumpei ARIYOSHI, Nao EIMORI, Ryo KONISHI, Akio KOBORI, Akira MURAKAMI, Asako YAMAYOSHI
- Organizer
  THE INTERNATIONAL CHEMICAL CONGRESS OF ACIFIC BASIN SOCIETIES 2015
- Place of Presentation
  Hawaii Convention Center
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] ピレン修飾核酸を用いた変異型mRNAの診断システム2015
- Author(s)
  小堀哲生・西村茜・中嶋康介・山吉　麻子・村上　章
- Organizer
  第61回高分子研究発表会
- Place of Presentation
  兵庫県民会館
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] 核酸ドラッグのRISCに対する結合親和性評価法の開発2015
- Author(s)
  小西　諒、松山　洋平、有吉　純平、小堀　哲生、村上　章、山吉　麻子
- Organizer
  第62回　日本生化学会近畿支部例会
- Place of Presentation
  立命館大学　びわこ・くさつキャンパス
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] 病原性リボヌクレオプロテインの活性制御を目指した機能性核酸分子の開発2015
- Author(s)
  有吉純平, 栄森奈緒, 小堀哲生, 村上章, 山吉麻子
- Organizer
  第5回4大学連携研究フォーラム
- Place of Presentation
  京都工芸繊維大学60周年記念館記念ホール
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26410179
[Presentation] 2-フェニルフランを導入したDNAオリゴマーによるエテノシトシン形成反応の開発と一塩基多型診断への応用2012
- Author(s)
  小堀哲生
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(横浜市)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] N^4位にソラレン誘導体を導入したデオキシシチジンを含む新規光応答性核酸の合成とその機能評価2012
- Author(s)
  小堀哲生
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(横浜市)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 2-フェニルフランを導入したDNAオリゴマーによるエテノシトシン形成反応の開発と一塩基多型診断への応用2012
- Author(s)
  小堀哲生, 他
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(神奈川県横浜市)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 光分解性保護基を導入した架橋性核酸の開発と機能評価2011
- Author(s)
  小堀哲生, 他
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場(茨城県つくば市)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 4-フルオロインドール誘導体を用いたDNA修復酵素の基質認識特性の解明2011
- Author(s)
  小堀哲生
- Organizer
  日本ケミカルバイオロジー学会
- Place of Presentation
  東京工業大学大岡山(東京)
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 核酸塩基部にソラレン誘導体を有する新規光架橋性アンチセンス核酸の合成と架橋特性の評価2011
- Author(s)
  小堀哲生
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2011
- Place of Presentation
  大阪大学(大阪府吹田市)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 光応答性核酸を用いた相補鎖捕捉反応の開発2011
- Author(s)
  小堀哲生
- Organizer
  第21回バイオ・高分子シンポジウム
- Place of Presentation
  関西大学(大阪府吹田市)
- Year and Date
  2011-07-25
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 光分解性保護基を導入した機能性核酸の架橋特性の評価2011
- Author(s)
  小堀哲生
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2011
- Place of Presentation
  大阪大学(大阪府吹田市)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] RISC機能の制御を目指した光架橋性アンチセンス核酸の開発2011
- Author(s)
  松山洋平, 小堀哲生
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2011
- Place of Presentation
  大阪大学(大阪府吹田市)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] ロメフロキサシンを導入したオリゴ核酸合成と、相補鎖酸化反応への応用2011
- Author(s)
  小堀哲生
- Organizer
  第57回高分子研究発表会
- Place of Presentation
  兵庫県民会館(兵庫県神戸市)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 光分解性保護基を導入した架橋性核酸の開発と機能評価2011
- Author(s)
  小堀哲生
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 光分解性保護基により活性を制御できる機能性核酸の合成と架橋特性の評価2011
- Author(s)
  小堀哲生
- Organizer
  第57回高分子研究発表会
- Place of Presentation
  兵庫県民会館(兵庫県神戸市)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] Interstrand photo-crosslinking using psoralen-incorporated oligodeoxyribonucleotides2010
- Author(s)
  A. Kobori
- Organizer
  International roundtable on nucleosides, nucleotides and nucleic acids
- Place of Presentation
  France
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] Interstrand photo-crosslinking using psoralen-incorporated oligodeoxyribonucleotides2010
- Author(s)
  A.Kobori, K.Takaya, M.Higuchi, A.Yamayoshi, A.Murakami
- Organizer
  International roundtable on nucleosides, nucleotides and nucleic acids
- Place of Presentation
  France, Lyon
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-22750154
[Presentation] 光架橋性塩基を有する人工核酸の合成とその機能評価2009
- Author(s)
  高屋和孝、樋口麻衣子、小堀哲生、山吉麻子、村上章
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  船橋市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] RNA特異的検出プローブによるショウジョウバエ初期胚発現mRNAの検出2009
- Author(s)
  上田貴子、脇玲子、山吉麻子、小堀哲生、山口政光、村上章
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  船橋市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 蛍光修飾RNAプローブを用いた初期応答遺伝子のリアルタイムイメージング(II)2009
- Author(s)
  脇玲子、上田貴子、山吉麻子、小堀哲生、村上章
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  船橋市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 蛍光修飾RNAプローブによる初期応答遺伝子のリアルタイムモニタリング2008
- Author(s)
  脇玲子、小堀哲生、山吉麻子、村上章
- Organizer
  第31回日本分子生物学会年会・第81回日本化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 光架橋性アンチセンス核酸による分子標的治療へのアプローチ(III)2008
- Author(s)
  樋口麻衣子、山吉麻子、小堀哲生、加藤聖子、和氣徳夫、村上章
- Organizer
  第88回日本化学会春季年会
- Place of Presentation
  東京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 蛍光核酸プローブによるショウジョウバエの発生過程におけるmRNAの検出2008
- Author(s)
  上田貴子、脇玲子、山吉麻子、小堀哲生、山口政光、村上章
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 光架橋型塩基を有するオリゴヌクレオチドの合成とその架橋特性2008
- Author(s)
  高屋和孝、樋口麻衣子、小堀哲生、山吉麻子、村上章
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] Excimer発光を利用した蛍光プローブによる疾患関連SNP検出2008
- Author(s)
  渡邊篤、上田貴子、山吉麻子、小堀哲生、村上章
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] デコイ核酸によるヒト乳癌細胞の増殖抑制機構2008
- Author(s)
  山吉麻子、島津典子、樋口麻衣子、小堀哲生、村上章
- Organizer
  第88回日本化学会春季年会
- Place of Presentation
  東京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 点突然変異陽性細胞における光架橋性アンチセンス核酸の細胞増殖抑制効果2008
- Author(s)
  樋口麻衣子、山吉麻子、小堀哲生、加藤聖子、和氣徳夫、村上章
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 蛍光核酸プローブによるショウジョウバエ初期胚でのmRNAの検出2008
- Author(s)
  山吉麻子、上田貴子、小堀哲生、山口政光、村上章
- Organizer
  第55回日本生化学会近畿支部例会
- Place of Presentation
  大阪市
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] フランを導入した機能性核酸のクロスリンク能の評価2008
- Author(s)
  小堀哲生・池田真人・山吉麻子・村上章
- Organizer
  日本化学会春期年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-18750147
[Presentation] 蛍光核酸プローブによるショウジョウバエ初期胚発現遺伝子の検出2008
- Author(s)
  上田貴子、村上章、山口政光、小堀哲生、山吉麻子
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] PIWI-Antagonistic Peptideを結合させたアンチセンス核酸の設計と機能評価2008
- Author(s)
  山吉麻子、桃川大毅、山田有希子、小堀哲生、村上章
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] RUNX1遺伝子SNPのENA導入型ピレン修飾RNAプローブによるSNP検出2008
- Author(s)
  村上章、渡邊篤、山吉麻子、小堀哲生、岸田綱朗、松田修
- Organizer
  第88回日本化学会春季年会
- Place of Presentation
  東京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ナフチリジン修飾蛍光核酸プローブによるSNP検出2008
- Author(s)
  小堀哲生、森隆、山吉麻子、村上章
- Organizer
  第88回日本化学会春季年会
- Place of Presentation
  東京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] RNAプローブを用いた初期応答遺伝子のリアルタイムイメージング(2)2008
- Author(s)
  脇玲子、山吉麻子、小堀哲生、村上章
- Organizer
  第55回日本生化学会近畿支部例会
- Place of Presentation
  大阪市
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ピレン修飾型RNAプローブを用いた標的RNAのタイムラプスイメージング2008
- Author(s)
  脇玲子、山吉麻子、小堀哲生、村上章
- Organizer
  第18回バイオ・高分子シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2008-07-25
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 光応答性塩基を有する人工核酸の開発2008
- Author(s)
  樋口麻衣子、高屋和孝、山吉麻子、小堀哲生、村上章
- Organizer
  第54回高分子研究発表会
- Place of Presentation
  神戸市
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ピレン修飾RNAプローブによるRUNX1遺伝子中のSNP検出2007
- Author(s)
  村上章、渡邊篤、坂本隆、山吉麻子、小堀哲生、岸田網朗、松田修
- Organizer
  第17回アンチセンスシンポジウム
- Place of Presentation
  金沢市
- Year and Date
  2007-12-04
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ENA導入型ピレン修飾RNAプローブを用いたSNPタイピング2007
- Author(s)
  村上章、渡邊篤、岸田網朗、山吉麻子、小堀哲生、松田修
- Organizer
  第53回高分子研究発表会(神戸)
- Place of Presentation
  神戸市
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] Gene expression by decoy approach (II) : Development of photo-cross-linked oligonucleotides duplex as a decoy DNA for estrogen receptor2007
- Author(s)
  Yamayoshi A., Shimadzu N., Higuchi M., Kobori A., Murakami A
- Organizer
  第34回核酸化学シンポジウム(Fifth International Symposium on Nucleic Acids Chemistry)
- Place of Presentation
  東京都
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 架橋型デコイ核酸によるヒト乳癌細胞増殖制御2007
- Author(s)
  山吉麻子、島津典子、樋口麻衣子、小堀哲生、村上章
- Organizer
  第17回アンチセンスシンポジウム
- Place of Presentation
  金沢市
- Year and Date
  2007-12-03
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 架橋型デコイ核酸の遺伝子発現制御の評価2007
- Author(s)
  山吉麻子、島津典子、小堀哲生、村上章
- Organizer
  第53回高分子研究発表会(神戸)
- Place of Presentation
  神戸市
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] Synthesis of naphthyridine-conjugated DNA probes and their application to SNPs typing2007
- Author(s)
  Kobori A., Mori T., Yamayoshi A., Murakami A.
- Organizer
  第34回核酸化学シンポジウム(Fifth International Symposium on Nucleic Acids Chemistry)
- Place of Presentation
  東京都
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ソラレン誘導体を修飾した光架橋性アンチセンス核酸の開発2007
- Author(s)
  樋口麻衣子、小堀哲生、山吉麻子、村上章
- Organizer
  第54回日本生化学会近畿支部例会
- Place of Presentation
  東京市
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ジアミノナフチリジンを導入した蛍光核酸プローブによる標的核酸の検出2007
- Author(s)
  小堀哲生、森隆、山吉麻子、村上章
- Organizer
  第2回日本ケミカルバイオロジー研究会
- Place of Presentation
  京都市
- Year and Date
  2007-05-09
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ENA導入型ピレン修飾RNAプローブを用いたSNP検出法の開発2007
- Author(s)
  村上章、渡邊篤、坂本隆、岸田網朗、松田修、小堀哲生
- Organizer
  第54回日本生化学会近畿支部例会
- Place of Presentation
  京都市
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] 光架橋型アンチセンス核酸のデザインと機能評価2007
- Author(s)
  樋口麻衣子、山吉麻子、小堀哲生、村上章
- Organizer
  第17回バイオ・高分子シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] Selective regulation of mutant K-ras mRNA expression by photo-cross-linking antisense oligonuleotide2007
- Author(s)
  Higuchi M., Yamayoshi A., Kobori A., Murakami A.
- Organizer
  第34回核酸化学シンポジウム(Fifth International Symposium on 第34回核酸化学シンポジウムFifth International Symposium on Nucleic Acids Chemistry)
- Place of Presentation
  東京都
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] Novel psoralen-conjugated antisense oligonucleotides having high photocross-linking efficiency2007
- Author(s)
  M.Higuchi, A.Yamayoshi, A.Kobori, A.Murakami
- Organizer
  American Chemical Society 23th National Meeting
- Place of Presentation
  Boston, USA
- Year and Date
  2007-08-19
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] エストロゲンレセプターを標的とした架橋型デコイ核酸による細胞増殖制御2007
- Author(s)
  山吉麻子、島津典子、樋口麻衣子、小堀哲生、村上章
- Organizer
  第54回日本生化学会近畿支部例会
- Place of Presentation
  京都市
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] RNAプローブによる初期応答遺伝子の発現プロファイリング2007
- Author(s)
  村上章、脇玲子、坂本隆、山吉麻子、小堀哲生
- Organizer
  第54回日本生化学会近畿支部例会
- Place of Presentation
  京都市
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ピレン修飾RNAプローブによるmRNAのin situ検出2007
- Author(s)
  村上章、脇玲子、坂本隆、山吉麻子、小堀哲生
- Organizer
  第53回高分子研究発表会(神戸)
- Place of Presentation
  神戸市
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] Synthesis and fluorescence properties of DANP-conjugated DNA probes for SNPs detection2007
- Author(s)
  Kobori A., Mori T., Yamayoshi A., Murakami A
- Organizer
  American Chemical Society 23th National Meeting
- Place of Presentation
  Boston, USA
- Year and Date
  2007-08-19
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] フランを導入したクロスリンク核酸の合成と評価2007
- Author(s)
  小堀哲生・小渕喬・池田真人・村上章
- Organizer
  生体機能関連化学シンポジウム
- Place of Presentation
  東北大学
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-18750147
[Presentation] ショウジョウバエのmRNAを標的とした蛍光プローブの設計とその評価2007
- Author(s)
  村上章、上田貴子、山吉麻子、小堀哲生、坂本隆
- Organizer
  第53回高分子研究発表会(神戸)
- Place of Presentation
  神戸市
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] Syntheses and cross-linking activities of furan-conjugated oligodeoxynucleotides.2007
- Author(s)
  A., Kobori・T., Kobuchi・M., Ikeda・A., Murakami
- Organizer
  American Chemical Society national meeting
- Place of Presentation
  Boston
- Year and Date
  2007-08-22
- Data Source
  KAKENHI-PROJECT-18750147
[Presentation] 点突然変異遺伝子の発現制御を目指したアンチセンス核酸の分子設計2007
- Author(s)
  樋口麻衣子、高屋和孝、山吉麻子、小堀哲生、村上章
- Organizer
  第56回高分子討論会
- Place of Presentation
  名古屋市
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-19550164
[Presentation] ソラレンを修飾した光架橋性アンチセンス核酸の開発2007
- Author(s)
  樋口麻衣子、高屋和孝、山吉麻子、小堀哲生、村上章
- Organizer
  第53回高分子研究発表会(神戸)
- Place of Presentation
  神戸市
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19550164

1. Waku Tomonori (30548699)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. MURAKAMI Akira (60210001)

# of Collaborated Projects: 2 results

# of Collaborated Products: 47 results
3. YAMAYOSHI Asako (70380532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 43 results
4. 松尾和哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOBORI Akio 小堀 哲生

Kobori Akio 小堀 哲生

KOBORI AKIO 小堀 哲生

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スプリットアプタマーを利用したエクソソーム定量システムの開発Principal Investigator

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細胞膜内滞留型ペプチドナノファイバーの開発とペプチド医薬デリバリーへの応用

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Development of ANCsome contaning aASO-RNaseH conjugatesPrincipal Investigator

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Direct cytoplasmic delivery of protein drugs by electric field-driven cell membrane-permeable peptide nanoneedles

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Development of quantitative SERS and their applicationsPrincipal Investigator

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Development of life-survey methods using SERS probesPrincipal Investigator

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Development of the recognition motif of DNA oxidation and its application to comprehensive analysis of DNA mutation.Principal Investigator

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Developments of in situ real-time monitoring system by fluorescent-probe and regulation protocols of functional RNAs

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新規蛍光プローブを用いたRNA検出法の開発Principal Investigator

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架橋型アンチセンス核酸による転写活性制御法の開発Principal Investigator

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[Book] Curr. Protoc. Nucleic acid Chem.2014

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[Journal Article] Oligonucleotide-based telomerase inhibitors with a photoresponsive α-chloroaldehyde2025

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[Journal Article] Ratiometric sandwich-type assays for RNAs with a point mutation using benzo[a]pyrene-modified probes2024

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KOBORI Akio 小堀哲生

Kobori Akio 小堀哲生

KOBORI AKIO 小堀哲生