Kido Taketomo 木戸丈友

… Alternative Names

KIDO Taketomo 木戸丈友

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Researcher Number	00401034
Other IDs
Affiliation (Current)	2025: 東京大学, 定量生命科学研究所, 特任准教授
Affiliation (based on the past Project Information) *help	2024: 東京大学, 定量生命科学研究所, 特任准教授 2020 – 2024: 東京大学, 定量生命科学研究所, 特任講師 2019: 東京大学, 定量生命科学研究所, 特任助教 2016 – 2017: 東京大学, 分子細胞生物学研究所, 助教 2013 – 2014: 東京大学, 分子細胞生物学研究所, 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 49030:Experimental pathology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / General anatomy (including histology/embryology) / General medical chemistry Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 53:Organ-based internal medicine and related fields / Transformative Research Areas, Section (III) / Experimental pathology
Keywords	Principal Investigator 肝臓 / iPS細胞 / 肝細胞 / 肝星細胞 / 線維化 / 肝疾患 / 星細胞 / 類洞内皮細胞 / リバイバル / 筋線維芽細胞 … More / 肝硬変 / ヒトiPS細胞 / 肝炎 / 非実質細胞 / 実質細胞 / 肝疾患モデル / マクロファージ / 細胞・組織 / 胆管上皮細胞 … More Except Principal Investigator オルガノイド / 肝臓 / 線維化 / 再生 / 肝疾患 / 自律神経 / 胆管疾患 / 交感神経 / リプログラミング / 線維症 / 肝星細胞 / 転移 / 膵癌 / 癌 / がん / マルチオミクス / 細胞老化 / 多階層マルチオミクス / 部分的リプログラミング / 老化 / 胆管発生 / 胆管上皮細胞 / CPM陽性肝前駆細胞 / 特性解析 / 全ゲノム解析 / 疾患特異的iPS細胞 / 胆道閉鎖症 / pathophysiology / hepatic progenitor cell / whole genome analysis / BA specific iPS cell / biliary atresia / 免疫 / 幹細胞 / 間葉系細胞 / 肝細胞 / 肝障害 / 胆管 / 肝炎 / イメージング / サイトカイン / 炎症 Less

肝星細胞リプログラミングによる線維症改善手法の開発
- Principal Investigator
  
  菱田友昭
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Wakayama Medical University
老化時計リバイバル機構の解明 -老化研究における新たなパラダイムシフトの総括
- Principal Investigator
  
  城村由和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kanazawa University
Elucidation of the revival mechanism in fibrogenic myofibroblastsPrincipal Investigator
- Principal Investigator
  
  木戸丈友
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
Generation of innervated liver organoid
- Principal Investigator
  
  谷水直樹
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Elucidation of the metastasis mechanism by constructing a metastasis model
- Principal Investigator
  
  関根圭輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  National Cancer Center Japan
Development of a novel liver disease model using genetically modified human induced pluripotent stem cells and analysis of fibrosis mechanismsPrincipal Investigator
- Principal Investigator
  
  Kido Taketomo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  The University of Tokyo
Elucidation of bile duct development and its disorder mechanism using biliary atresia-specific iPS cells
- Principal Investigator
  
  Suzuki Kan
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Dokkyo Medical University
  The University of Tokyo
Development of a hepatitis modelPrincipal Investigator
- Principal Investigator
  
  Kido Taketomo
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
Development of high throughput screening system usign human iPS-derived hepatocytesPrincipal Investigator
- Principal Investigator
  
  KIDO Taketomo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  The University of Tokyo
Cellular interaction in liver inflammation and regeneration
- Principal Investigator
  
  Miyajima Atsushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
Generation of hepatocyte from iPS cells and establishment of human liver chimeric micePrincipal Investigator
- Principal Investigator
  
  KIDO Taketomo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Patent

[Book] iPS細胞からの肝類洞壁細胞への分化誘導法2021
- Author(s)
  姫野　美沙緒、木戸　丈友
- Total Pages
  7
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-21H02710
[Book] iPS細胞を用いた創薬研究-肝線維化治療薬の開発2021
- Author(s)
  木戸　丈友、宮島　篤
- Total Pages
  3
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-21H02710
[Journal Article] Dynamic, IPSC-derived hepatic tissue tri-culture system for the evaluation of liver physiology in vitro2024
- Author(s)
  Scheidecker Benedikt、Poulain Stephane、Sugimoto Masahiro、Kido Taketomo、Kawanishi Takumi、Miyajima Atsushi、Kim Soo Hyeon、Arakawa Hiroshi、Kato Yukio、Nishikawa Masaki、Danoy Mathieu、Sakai Yasuyuki、Leclerc Eric
- Journal Title
  
  Biofabrication
  
  Volume: 16 Issue: 2 Pages: 025037-025037
- DOI
  10.1088/1758-5090/ad30c5
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K25188
[Journal Article] A highly efficient cell culture method using oxygen‐permeable PDMS‐based honeycomb microwells produces functional liver organoids from human induced pluripotent stem cell‐derived carboxypeptidase M liver progenitor cells2024
- Author(s)
  Utami Tia、Danoy Mathieu、Khadim Rubina Rahaman、Tokito Fumiya、Arakawa Hiroshi、Kato Yukio、Kido Taketomo、Miyajima Atsushi、Nishikawa Masaki、Sakai Yasuyuki
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 121 Issue: 4 Pages: 1178-1190
- DOI
  10.1002/bit.28640
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710
[Journal Article] Development of a novel co-culture system using human pancreatic cancer cells and human iPSC-derived stellate cells to mimic the characteristics of pancreatic ductal adenocarcinoma in?vitro2023
- Author(s)
  Kometani Tatsuya、Kamo Koki、Kido Taketomo、Hiraoka Nobuyoshi、Chibazakura Taku、Unno Kenji、Sekine Keisuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 658 Pages: 1-9
- DOI
  10.1016/j.bbrc.2023.03.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15434, KAKENHI-PROJECT-21K05510, KAKENHI-PROJECT-22K19575, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K24400
[Journal Article] Using human induced pluripotent stem cell-derived liver cells to investigate the mechanisms of liver fibrosis in vitro2023
- Author(s)
  Koui Yuta、Kido Taketomo
- Journal Title
  
  Biochemical Society Transactions
  
  Volume: 51 Issue: 3 Pages: 1271-1277
- DOI
  10.1042/bst20221421
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710
[Journal Article] Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis2023
- Author(s)
  Tsuchiya Y, Seki T, Kobayashi K, Komazawa-Sakon S, Shichino S, Nishina T, Fukuhara K, Ikejima K, Nagai H, Igarashi Y, Ueha S, Oikawa A, Tsurusaki S, Yamazaki S, Nishiyama C, Mikami T, Yagita H, Okumura K, Kido T, Miyajima A, Matsushima K, Imasaka M, Araki K, Imamura T, Ohmuraya M, Tanaka M, Nakano H
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 6304-6304
- DOI
  10.1038/s41467-023-42058-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20666, KAKENHI-PROJECT-22K07007, KAKENHI-PROJECT-23K06489, KAKENHI-PROJECT-21K07922, KAKENHI-PLANNED-22H05064, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K26860, KAKENHI-PROJECT-23K27398
[Journal Article] Transcriptomic and proteomic studies suggest the establishment of advanced zonation‐like profiles in humaninduced pluripotent stem cell‐derived liver sinusoidal endothelial cells and carboxypeptidase M‐positive liver progenitor cells cocultured in a fluidic microenvironment2023
- Author(s)
  Danoy M, Poulain S, Scheidecker B, Kim SH, Kido T, Miyajima A, Sakai Y, Leclerc E
- Journal Title
  
  Hepatology research
  
  Volume: 1 Issue: 7 Pages: 1-14
- DOI
  10.1111/hepr.13893
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25188, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710
[Journal Article] Optimization of physical microenvironment to maintain the quiescence of human induced pluripotent stem cell‐derived hepatic stellate cells2023
- Author(s)
  Gong Ya、Danoy Mathieu、Kido Taketomo、Mitsuhashi Kento、Choi Hyunjin、Matsugi Tomoaki、Yang Jingjing、Esashika Katsuhiro、Takahashi Jun、Nishikawa Masaki、Ito Taichi、Miyajima Atsushi、Sakai Yasuyuki
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 120 Issue: 8 Pages: 2345-2356
- DOI
  10.1002/bit.28485
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710
[Journal Article] Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis2023
- Author(s)
  Takeda Nobutaka、Tsuchiya Atsunori、Mito Masaki、Natsui Kazuki、Natusi Yui、Koseki Yohei、Tomiyoshi Kei、Yamazaki Fusako、Yoshida Yuki、Abe Hiroyuki、Sano Masayuki、Kido Taketomo、Yoshioka Yusuke、Kikuta Junichi、Itoh Tohru、Nishimura Ken、Ishii Masaru、Ochiya Takahiro、Miyajima Atsushi、Terai Shuji
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 43 Issue: 1 Pages: 48-48
- DOI
  10.1186/s41232-023-00299-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19423, KAKENHI-PROJECT-22K19933, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02518, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K24128
[Journal Article] Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state2023
- Author(s)
  Nakano Yasuhiro、Itoh Tohru、Tanaka Minoru、Miyajima Atsushi、Kido Taketomo
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.11.01.564270
- Open Access
- Data Source
  KAKENHI-PROJECT-22K19423, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02518, KAKENHI-PROJECT-21H02710
[Journal Article] Influence of CPM-dependent sorting on the multi-omics profile of hepatocyte-like cells matured in microscale biochips2022
- Author(s)
  Mathieu Danoy、Stephane Poulain、Benedikt Scheidecker、Rachid Jellali、Yannick Tauran、Marjorie Leduc、Johanna Bruce、Francoise Gilard、Bertrand Gakiere、Hiroshi Arakawa、Yukio Kato、Soo Hyeon Kim、Taketomo Kido、Atsushi Miyajima、Yasuyuki Sakai、Eric Leclerc
- Journal Title
  
  Biochemical Engineering Journal
  
  Volume: 181 Pages: 108408-108408
- DOI
  10.1016/j.bej.2022.108408
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22491, KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-21H02710
[Journal Article] Co-culture Model for Hepatitis B Virus Infection Using iPSC-Derived Liver Progenitor Cells and Liver Sinusoidal Endothelial Cells2022
- Author(s)
  Misao HIMENO, Shin-Wei Chen, Taketomo Kido
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2544 Pages: 107-117
- DOI
  10.1007/978-1-0716-2557-6_7
- ISBN
  9781071625569, 9781071625576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17042, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-20J40236
[Journal Article] Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis2021
- Author(s)
  Takeuchi S, Tsuchiya A, Iwasawa T、Nojiri S、Watanabe T、Ogawa M、Yoshida T、Fujiki K、Koui Y、Kido T、Yoshioka Y、Fujita M、Kikuta J、Itoh T、Takamura M、Shirahige K、Ishii M、Ochiya T、Miyajima A、Terai S
- Journal Title
  
  npj Regenerative Medicine
  
  Volume: 6 Issue: 1
- DOI
  10.1038/s41536-021-00132-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21384, KAKENHI-PROJECT-18K07903, KAKENHI-PROJECT-19H03636, KAKENHI-PROJECT-21H02710
[Journal Article] Multi-omics analysis of hiPSCs-derived HLCs matured on-chip revealed patterns typical of liver regeneration2021
- Author(s)
  Danoy M, Tauran Y, Poulain S, Jellali R, Bruce J, Leduc M, Gall M, Koui Y, Arakawa H, Gilard F, Kato Y, Kido T, Miyajima A, Sakai Y, Leclerc E
- Journal Title
  
  Biotechnology & Bioengineering
  
  Volume: 118 Issue: 10 Pages: 3716-3732
- DOI
  10.1002/bit.27667
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-16H06328, KAKENHI-PROJECT-21H02710
[Journal Article] Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling2021
- Author(s)
  Koui Yuta、Himeno Misao、Mori Yusuke、Nakano Yasuhiro、Saijou Eiko、Tanimizu Naoki、Kamiya Yoshiko、Anzai Hiroko、Maeda Natsuki、Wang Luyao、Yamada Tadanori、Sakai Yasuyuki、Nakato Ryuichiro、Miyajima Atsushi、Kido Taketomo
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 12 Pages: 3050-3063
- DOI
  10.1016/j.stemcr.2021.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07958, KAKENHI-PROJECT-18K15773, KAKENHI-PROJECT-20J40236, KAKENHI-PLANNED-17H06331, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-20K05843, KAKENHI-PROJECT-20K17042
[Journal Article] Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment2021
- Author(s)
  Danoy Mathieu、Tauran Yannick、Poulain Stephane、Jellali Rachid、Bruce Johanna、Leduc Marjorie、Le Gall Morgane、Koui Yuta、Arakawa Hiroshi、Gilard Francoise、Gakiere Bertrand、Kato Yukio、Plessy Charles、Kido Taketomo、Miyajima Atsushi、Sakai Yasuyuki、Leclerc Eric
- Journal Title
  
  APL Bioengineering
  
  Volume: 5 Issue: 2 Pages: 026104-026104
- DOI
  10.1063/5.0041227
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22491, KAKENHI-PROJECT-21H02710
[Journal Article] Modulation of hepatitis B virus infection by epidermal growth factor secreted from liver sinusoidal endothelial cells2020
- Author(s)
  Shin-Wei Chen, Misao Himeno, Yuta Koui, Masaya Sugiyama, Hironori Nishitsuji, Masashi Mizokami, Kunitada Shimotohno, Atsushi Miyajima, Taketomo Kido
- Journal Title
  
  Scientific Reports
  
  Volume: 10(1):14349 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-020-71453-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15773, KAKENHI-PROJECT-20K17042, KAKENHI-PROJECT-18K07161, KAKENHI-PROJECT-19K22614
[Journal Article] An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells.2017
- Author(s)
  Koui Y, Kido T, Ito T, Oyama H, Chen SW, Katou Y, Shirahige K, Miyajima A.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 9 Issue: 2 Pages: 490-498
- DOI
  10.1016/j.stemcr.2017.06.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02369, KAKENHI-PROJECT-16J05987, KAKENHI-PROJECT-16K18975
[Journal Article] 1. CPM is a useful cell surface marker to isolate expandable bi-potential liver progenitor cells derived from human iPS cells.2015
- Author(s)
  Kido T, Koui Y, Suzuki K, Kobayashi A, Miura Y, Chen EY, Tanaka M, Miyajima A.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 5 Issue: 4 Pages: 508-515
- DOI
  10.1016/j.stemcr.2015.08.008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15115, KAKENHI-PLANNED-26110007, KAKENHI-PROJECT-26253023
[Patent] 活性化星細胞を脱活性化する方法2022
- Inventor(s)
  宮島篤、木戸丈友、中野泰博、宮戸みつる
- Industrial Property Rights Holder
  宮島篤、木戸丈友、中野泰博、宮戸みつる
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21H02710
[Patent] 活性化肝星細胞に対する脱活性化誘導剤スクリーニング系2022
- Inventor(s)
  宮島篤、木戸丈友、中野泰博、宮戸みつる
- Industrial Property Rights Holder
  宮島篤、木戸丈友、中野泰博、宮戸みつる
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21H02710
[Patent] アザ－アルテミシニン類を含む線維症治療薬2022
- Inventor(s)
  宮島篤、木戸丈友、大栗博毅、他６名
- Industrial Property Rights Holder
  宮島篤、木戸丈友、大栗博毅、他６名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-082568
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21H02710
[Patent] 肝細胞及び肝非実質細胞、並びにそれらの調製方法2016
- Inventor(s)
  宮島篤、木戸丈友、厚井悠太、小林彩香
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-03-16
- Data Source
  KAKENHI-PROJECT-26253023
[Presentation] Development of anti-HBV agents that contain alkaloidal scaffolds bearing Michael acceptors2024
- Author(s)
  Misao Himeno, Kaneko Nobuto, Hiroki Kubota, Taketomo Kido, Atsushi Miyajima, Masaya Sugiyama, Meng Ling Moi, Hiroki Oguri
- Organizer
  The Joint 24th International Conference on Emerging Infectious Diseases in the Pacific Rim of the USJCMSP in collaboration with the 2nd International Symposium for IDRIC
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H03836
[Presentation] Development of anti-HBV agents that contain alkaloidal scaffolds bearing Michael acceptors2024
- Author(s)
  Misao Himeno, Kaneko Nobuto, Hiroki Kubota, Taketomo Kido, Atsushi Miyajima, Masaya Sugiyama, Meng Ling Moi, Hiroki Oguri
- Organizer
  The Joint 24th International Conference on Emerging Infectious Diseases in the Pacific Rim of the USJCMSP in collaboration with the 2nd International Symposium for IDRIC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] B型肝炎ウイルス複製阻害活性を示すマイケルアクセプター含有アルカロイド類似化合物の同定2023
- Author(s)
  姫野　美沙緒、金子　信人、久保田　大貴、木戸　丈友、宮島　篤、杉山　真也、モイ　メンリン、大栗　博毅
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PLANNED-23H03836
[Presentation] B型肝炎ウイルス複製阻害活性を示すマイケルアクセプター含有アルカロイド類似化合物の同定2023
- Author(s)
  姫野　美沙緒、金子　信人、久保田　大貴、木戸　丈友、宮島　篤、杉山　真也、モイ　メンリン、大栗　博毅
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] 抗線維化作用を有する新規リゾホスファチジルセリン誘導体の創製2023
- Author(s)
  陳　露瑩、木戸　丈友、宮島　篤、大和田　智彦
- Organizer
  第37回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PLANNED-23H03836
[Presentation] 抗線維化作用を有する新規リゾホスファチジルセリン誘導体の創製2023
- Author(s)
  陳　露瑩、木戸　丈友、宮島　篤、大和田　智彦
- Organizer
  第37回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] マイケルアクセプターを有するアルカロイド類似化合物群の骨格多様化合成による抗B型肝炎ウイルス活性分子の創製2023
- Author(s)
  金子信人、久保田大貴、姫野美沙緒、木戸丈友、宮島篤、大栗博毅
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] ヒトiPS細胞由来静止期肝星細胞を用いた肝線維化治療薬の開発2022
- Author(s)
  木戸　丈友、大栗　博毅、宮島　篤
- Organizer
  第127回　日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] ヒトiPS細胞由来活性化肝星細胞に対する脱活性化誘導に立脚した肝線維症治療薬の開発2022
- Author(s)
  中野泰博、宮島篤、木戸丈友
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] ヒトiPS細胞技術を用いた肝線維症治療薬の開発2022
- Author(s)
  木戸丈友、中野泰博、大栗博毅、宮島篤
- Organizer
  第95回　日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] iPS細胞由来静止期肝星細胞を用いた創薬研究2021
- Author(s)
  木戸　丈友、大栗　博毅、宮島　篤
- Organizer
  第35回　肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-21H02710
[Presentation] 2.iPS細胞を用いた肝線維症治療薬の同定2020
- Author(s)
  木戸　丈友、厚井　悠太、前田　夏希、王　路遥、酒井　康行、宮島　篤
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] アザ-アルテミシニンによる肝星細胞の活性化抑制評価2020
- Author(s)
  金子信人、姫野美沙緒、高橋紀人、Bonepally Karunakar Reddy、堀優太郎、宮島篤、大栗博毅、木戸丈友
- Organizer
  第34回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] 1.ヒトiPS細胞由来肝構成細胞の樹立と応用2020
- Author(s)
  木戸　丈友、厚井　悠太、森　勇介、山田　忠範、宮島　篤
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] Modulation of Hepatitis B virus Infection by Epidermal gGowth Factor2020
- Author(s)
  Shin-Wei Chen, Misao Himeno, Yuta Koui, Masaya Sugiyama, Hironori Nishitsuji, Masashi Mizokami, Kunitada Shimotohno, Atsushi Miyajima and Taketomo Kido
- Organizer
  第27回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] ヒトiPS細胞由来肝星細胞の創薬研究への応用2019
- Author(s)
  木戸　丈友、厚井　悠太、森　勇介、山田　忠範、宮島　篤
- Organizer
  第33回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] iPS細胞由来肝星細胞を用いた肝細胞共培養モデルの開発2019
- Author(s)
  森　勇介、樋口　珠美、森村　馨、厚井　悠太、木戸　丈友、宮島　篤、我妻　昭彦、山田　忠範、山本　武
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] Generation of quiescent hepatic stellate cells from human iPSCs for drug discovery2019
- Author(s)
  Taketomo Kido, Yuta Koui, Atsushi Miyajima
- Organizer
  Cold Spring Harbor Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] iPS細胞由来星細胞を用いた肝線維症治療薬スクリーニング系の開発2019
- Author(s)
  厚井　悠太、宮島　篤、木戸　丈友
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] 星細胞と肝細胞の三次元共培養モデルによるB型肝炎ウイルス感染系の確立2019
- Author(s)
  姫野美沙緒、厚井悠太、陳欣蔚、西辻裕紀、杉山真也、溝上雅史、木戸丈友、宮島篤
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] GENERATION OF HUMAN IPSC-DERIVED QUIESCENT HEPATIC STELLATE CELLS FOR DRUG DISCOVERY AND LIVER DISEASE MODELING2019
- Author(s)
  Yuta Koui, Atsushi Miyajima, Taketomo Kido
- Organizer
  ISSCR annual meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22614
[Presentation] ヒトiPS細胞由来肝星細胞の活性化制御2018
- Author(s)
  厚井悠太、木戸丈友、大山裕棋、Chen Shin-Wei、姫野（黒木）美沙緒、宮島篤
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] 胆汁酸の排出機構を備えた肝組織の構築2018
- Author(s)
  大山裕棋、木戸丈友、姫野（黒木）美沙緒、厚井悠太、Chen Shin-Wei、宮島篤
- Organizer
  第28回日本肝臓医生物学研究会
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] 機能的胆管様構造の導入による肝組織の構築2018
- Author(s)
  大山裕棋、木戸丈友、厚井悠太、Chen Shin-Wei、姫野（黒木）美沙緒、宮島篤
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] ヒトiPS細胞由来肝非実質細胞の樹立2017
- Author(s)
  厚井悠太、木戸丈友、大山裕棋、Chen Shin-Wei、宮島篤
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] 肝組織構築に向けた効率的なヒトiPS細胞由来胆管上皮細胞分化誘導系の樹立2017
- Author(s)
  大山裕棋、木戸丈友、厚井悠太、Chen Shin-Wei、宮島篤
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] Development of a human liver model using iPSC-derived parenchymal and non-parenchymanl cells2017
- Author(s)
  Yuta Koui, Taketomo Kido, Hiroki Oyama, Shin-Wei Chen, Atsushi Miyajima
- Organizer
  Cold Spring Harbor Asia Conference Liver Biology, Diseases & Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] Development of an in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells2017
- Author(s)
  Yuta Koui, Taketomo Kido, Hiroki Oyama, Shin-Wei Chen, Atsushi Miyajima
- Organizer
  ISSCR annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] 肝発生過程に基づいたヒトiPS細胞由来肝非実質細胞の誘導と肝組織モデルへの応用2017
- Author(s)
  厚井悠太、木戸丈友、大山裕棋、Chen Shin-Wei、宮島篤
- Organizer
  第24回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] Development of HBV infection model using iPS-derived hepatic cells2017
- Author(s)
  Chen Shin-Wei、木戸丈友、厚井悠太、大山裕棋、杉山真也、溝上雅史、宮島篤
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] iPS細胞由来肝類洞壁細胞の作製とその応用2017
- Author(s)
  木戸丈友、厚井悠太、大山裕棋、Chen Shin-Wei、宮島篤
- Organizer
  第24回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] ヒトiPS細胞由来CPM陽性肝前駆細胞からの成熟肝細胞の誘導2016
- Author(s)
  木戸　丈友、厚井　悠太、小林　彩香、大山　裕棋、田中　稔、宮島　篤
- Organizer
  第１５回　日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26253023
[Presentation] ヒトiPS細胞由来肝細胞へのHBV感染2016
- Author(s)
  木戸丈友、杉山真也、厚井悠太、小林彩香、大山裕棋、Chen Shin-Wei、溝上雅史、宮島篤
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター（大阪府大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] ヒトiPS細胞由来肝類洞壁細胞の樹立2016
- Author(s)
  木戸丈友、厚井悠太、大山裕棋、Chen Shin-Wei、宮島篤
- Organizer
  第30回肝類洞壁細胞研究会学術集会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K18975
[Presentation] ヒトiPS細胞由来肝前駆細胞の二分化能の解析2015
- Author(s)
  木戸丈友、厚井悠太、田中稔、小林彩香、宮島篤
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-26253023
[Presentation] ヒトiPS細胞からの機能的肝細胞の大量調製法の確立2014
- Author(s)
  木戸　丈友、田中　稔、篠原　満利恵、Wenjin Xiao、酒井　康行、宮島　篤
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25870145
[Presentation] ヒトiPS細胞から肝類洞内皮細胞の分化誘導2014
- Author(s)
  木戸　丈友、伊藤　利将、厚井　悠太、宮島　篤
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25870145
[Presentation] Generation of liver progenitors from human iPS cells2013
- Author(s)
  Taketomo Kido, Minoru Tanaka, Yasuyuki Sakai, Atsushi Miyajima
- Organizer
  第20回肝細胞研究会
- Place of Presentation
  大阪、大阪国際会議場
- Data Source
  KAKENHI-PROJECT-25870145
[Presentation] ヒトiPS細胞からの肝類洞内皮細胞への分化誘導と成熟肝細胞の作製への応用
- Author(s)
  厚井悠太、木戸丈友、小林彩香、宮島篤
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25870145
[Presentation] 創薬研究に向けたiPS細胞から機能的肝組織の構築へ
- Author(s)
  木戸　丈友
- Organizer
  バイオテクノロジー懇談会
- Place of Presentation
  東京、東京大学
- Data Source
  KAKENHI-PROJECT-25870145
[Presentation] ヒトiPS細胞由来肝前駆細胞の二分化能の解析
- Author(s)
  木戸丈友、厚井悠太、田中稔、小林彩香、宮島篤
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25870145
[Presentation] ヒトiPS細胞由来成熟肝細胞の誘導における肝非実質細胞の役割
- Author(s)
  小林彩香、木戸丈友、厚井悠太、宮島篤
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25870145

1. TANAKA Minoru (80321909)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 菱田友昭 (80521062)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Miyajima Atsushi (50135232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. ITOH Tohru (50396917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. ENOMOTO Yutaka (20608210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAIJOU Eiko (60376647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Suzuki Kan (80598508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 藤代準 (60528438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 林洋平 (90780130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 城村由和 (40616322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 矢木宏和 (70565423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中野泰博 (80755439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 関根圭輔 (00323569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 谷水直樹 (00333386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 須藤亮 (20407141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. DANOY MATHIEU

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
17. 米谷達哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 藤木克則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 姫野美沙緒

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 酒井康行

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 荒川大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. LECLERC Eric

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 白髭克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kido Taketomo 木戸 丈友

KIDO Taketomo 木戸 丈友

Research Projects

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Co-Researchers

肝星細胞リプログラミングによる線維症改善手法の開発

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老化時計リバイバル機構の解明 -老化研究における新たなパラダイムシフトの総括

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Elucidation of the revival mechanism in fibrogenic myofibroblastsPrincipal Investigator

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Generation of innervated liver organoid

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Elucidation of the metastasis mechanism by constructing a metastasis model

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Development of a novel liver disease model using genetically modified human induced pluripotent stem cells and analysis of fibrosis mechanismsPrincipal Investigator

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Elucidation of bile duct development and its disorder mechanism using biliary atresia-specific iPS cells

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Development of a hepatitis modelPrincipal Investigator

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Development of high throughput screening system usign human iPS-derived hepatocytesPrincipal Investigator

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Cellular interaction in liver inflammation and regeneration

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Generation of hepatocyte from iPS cells and establishment of human liver chimeric micePrincipal Investigator

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[Book] iPS細胞からの肝類洞壁細胞への分化誘導法2021

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[Book] iPS細胞を用いた創薬研究-肝線維化治療薬の開発2021

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Kido Taketomo 木戸丈友

KIDO Taketomo 木戸丈友