Sekiguchi Hiroshi 関口博史

… Alternative Names

SEKIGUCHI Hiroshi 関口博史

関口博史セキグチヒロシ

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Researcher Number	00401563
Other IDs	https://orcid.org/0000-0001-7590-3624
Affiliation (Current)	2025: 公益財団法人高輝度光科学研究センター, 回折・散乱推進室, 主幹研究員 2025: 公益財団法人高輝度光科学研究センター, 研究プロジェクト推進室, 主幹研究員
Affiliation (based on the past Project Information) *help	2024: 公益財団法人高輝度光科学研究センター, 研究プロジェクト推進室, 主幹研究員 2023 – 2024: 公益財団法人高輝度光科学研究センター, 散乱・イメージング推進室, 主幹研究員 2020 – 2023: 公益財団法人高輝度光科学研究センター, 回折・散乱推進室, 主幹研究員 2016 – 2018: 公益財団法人高輝度光科学研究センター, 利用研究促進部門, 主幹研究員 2014 – 2015: 公益財団法人高輝度光科学研究センター, 利用研究促進部門, 副主幹研究員 … More 2012 – 2015: 公益財団法人高輝度光科学研究センター, 利用研究促進部門, 研究員 2012: 高輝度光科学研究センター, 利用研究促進部門, 研究員 2010 – 2012: 東京大学, 大学院・新領域創成科学研究科, 特任助教 2011: 東京工業大学, 大学院・生命理工学研究科, 助教 2008: 東京工業大学, 大学院・理生命工学研究科, 助教 2005 – 2006: 東京工業大学, 大学院生命理工学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biophysics / Science and Engineering Except Principal Investigator Nanomaterials/Nanobioscience / Basic Section 28040:Nanobioscience-related / Basic Section 35020:Polymer materials-related / Basic Section 38030:Applied biochemistry-related / Medium-sized Section 28:Nano/micro science and related fields / Applied biochemistry / Science and Engineering / Biophysics
Keywords	Principal Investigator ナノ結晶 / 揺らぎ / 1分子計測 / 膜タンパク質 / ダイナミクス計測 / １分子計測 / 構造変化 / 分子内運動 / 生物物理 Except Principal Investigator X線 … More / 膜タンパク質 / X線１分子追跡法 / 金属イオン結合 / PCR / mRNA / AFM / X線1分子追跡法 / 構造変化 / １分子計測 / 原子間力顕微鏡 / 1分子動態 / オペランド計測 / タンパク質 / DXT / 分子動態 / 天然高分子 / ガラス転移温度 / X線回折 / 応力緩和 / 結晶ヤング率 / 高次組織 / 小角X線散乱 / 広角X線回折 / 高分子結晶 / 極限弾性率 / 動的構造変化 / 構造機能相関 / PET分解 / 酵素 / マイクロ秒高速1分子 / 分子内部動態 / レーザー励起 / X線1分子動態 / 光励起１分子計測 / レーザー励起動態 / 1分子内部動態計測 / ヘモグロビン / 光励起 / タンパク質1分子動態 / へモグロビン / アロステリック効果 / 動的挙動 / 構造エントロピー / 蛋白質 / 動的構造 / biomolecules / membrane protein / plasma membrane / Nano-manipulator / Cell / 単一細胞モニター / 単一生細胞の生化学 / 単一生細胞モニター / 単一生細胞モニタ / 単一細胞の生化学 / 遺伝子DNA導入 / 膜タンパク質採取 / mRNA採取 / 細胞手術 / ナノマニュピュレーター / 生体分子 / 細胞膜 / ナノマニピュレーター / 培養細胞 / 1分子 / 中性子 / バイオ計測 / Ｘ線１分子追跡法 / 蛋白質構造動態 / 新規計測手段 / 1分子動態情報 / 局部構造 / バイオテクノロジー / Ｘ線1分子追跡法 / 3次元分子内部動態情報 / Ｘ線1分子計測 / 価数変化 / 蛍光Ｘ線ホログラフィー / 結晶化 / タンパク質分子 / 標識・無標識法 / 蛍光X線ホログラフィー / シャペロニン / 古細菌 / 構造変化機構 / シャペロン / フォールディング / 分子内運動 / X線集光 / 1分子計測 / ナノバイオ / 放射光 / ナノ計測 / 1分子イメージング / ナノバイオメカニクス / 力学的信号伝達系 / 力学的分光法 / 原子間力顕微鏡(AFM) / アクチン繊維 / ナノ力学 / 生体情報伝達 / 分子動力学 / 有限要素法 / パキシリン / リンカータンパク質 / 生体ナノ力学 / 生体力学情報伝達 / アクチン / ストレスファイバー / 分子間相互作用力 / ネットワーク力学 / 細胞骨格 Less

X線を用いた高速１分子運動解析による膜タンパク質オペランド計測の実現
- Principal Investigator
  
  三尾和弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Study of Serious Problems of Conventional Methods in the Evaluation of Ultimate Mechanical Property of Polymer Crystals as a Guiding Principle for the Development of Ultra-Strong Polymers
- Principal Investigator
  
  田代孝二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 35020:Polymer materials-related
- Research Institution
  公益財団法人科学技術交流財団(あいちシンクロトロン光センター、知の拠点重点研究プロジェクト統括部)
Structural dynamics of cutinase Cut190 upon Ca2+ binding and molecular mechanism of PET degradation by Cut190
- Principal Investigator
  
  Oda Masayuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Kyoto Prefectural University
Determination of single hemoglobin dynamics with x-rays
- Principal Investigator
  
  SASAKI YUJI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 28:Nano/micro science and related fields
- Research Institution
  The University of Tokyo
3D Active Site Science in Biology
- Principal Investigator
  
  Sasaki Yuji
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Quantification of protein conformational entropy on helix-bundle formation
- Principal Investigator
  
  Masayuki Oda
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto Prefectural University
Studies on the subunit cooperative mechanism in the reaction cycle of group 2 chaperonin
- Principal Investigator
  
  YOHDA MASAFUMI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Tokyo University of Agriculture and Technology
Multiscale motion analysis of membrane proteins at neuromuscular junctionPrincipal Investigator
- Principal Investigator
  
  SEKIGUCHI Hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Japan Synchrotron Radiation Research Institute
高速１分子動態計測による膜タンパク質機能発現機構の解明Principal Investigator
- Principal Investigator
  
  関口博史
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Japan Synchrotron Radiation Research Institute
  The University of Tokyo
Development of Compact Diffracted X-ray Tracking Instrumentation
- Principal Investigator
  
  SASAKI Yuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  The University of Tokyo
Single Molecule Mechanics and Computer Modeling of Cascading System of Biological Information Transfer
- Principal Investigator
  
  IKAI Atsushi
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Tokyo Institute of Technology
Time lapse nano-analysis of single cell components : Development of Harvesting, Identification and Injection Methods of Functional Molecules
- Principal Investigator
  
  IKAI Atsushi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Tokyo Institute of Technology

[Book] Advances in Chemical Physics : Single Molecule Biophysics : Experiments and Theory(Eds : T. Komatsuzaki et al.)2011
- Author(s)
  Atsushi Ikai Rehana Afrin Hiroshi Sekiguchi
- Total Pages
  512
- Publisher
  Force to Unbind Ligand : Receptor Complexes and the Internal Rigidity of Globular Proteins Probed by Single-Molecule Force Spectroscopy
- Data Source
  KAKENHI-PROJECT-19GS0418
[Book] Applied Scanning Probe Method IX (B. Bhushan ed.)2008
- Author(s)
  Kim, H., Uehara, H., Afrin, R., Sekiguchi, H., Arakawa, H., Osada T and Ikai A.
- Total Pages
  387
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19GS0418
[Journal Article] Real-time tilting and twisting motions of ligand-bound states of α7 nicotinic acetylcholine receptor2024
- Author(s)
  Yang Yue、Arai Tatsuya、Sasaki Daisuke、Kuramochi Masahiro、Inagaki Hidetoshi、Ohashi Sumiko、Sekiguchi Hiroshi、Mio Kazuhiro、Kubo Tai、Sasaki Yuji C.
- Journal Title
  
  European Biophysics Journal
  
  Volume: 53 Issue: 1-2 Pages: 15-25
- DOI
  10.1007/s00249-023-01693-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0100, KAKENHI-PROJECT-22K05567, KAKENHI-PROJECT-23K26511
[Journal Article] Comparison of the Molecular Motility of Tubulin Dimeric Isoforms: Molecular Dynamics Simulations and Diffracted X-ray Tracking Study2023
- Author(s)
  Yamane Tsutomu、Nakayama Takahiro、Ekimoto Toru、Inoue Masao、Ikezaki Keigo、Sekiguchi Hiroshi、Kuramochi Masahiro、Terao Yasuo、Judai Ken、Saito Minoru、Ikeguchi Mitsunori、Sasaki Yuji C.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 20 Pages: 15423-15423
- DOI
  10.3390/ijms242015423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K26511
[Journal Article] Ligand-Dependent Intramolecular Motion of Native Nicotinic Acetylcholine Receptors Determined in Living Myotube Cells via Diffracted X-ray Tracking2023
- Author(s)
  Oishi Koichiro、Nagamori Mayu、Kashino Yasuhiro、Sekiguchi Hiroshi、Sasaki Yuji C.、Miyazawa Atsuo、Nishino Yuri
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 15 Pages: 12069-12069
- DOI
  10.3390/ijms241512069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K26511
[Journal Article] Real-Time Observation of Capsaicin-Induced Intracellular Domain Dynamics of TRPV1 Using the Diffracted X-ray Tracking Method2023
- Author(s)
  Mio Kazuhiro、Ohkubo Tatsunari、Sasaki Daisuke、Arai Tatsuya、Sugiura Mayui、Fujimura Shoko、Nozawa Shunsuke、Sekiguchi Hiroshi、Kuramochi Masahiro、Sasaki Yuji C.
- Journal Title
  
  Membranes
  
  Volume: 13 Issue: 8 Pages: 708-708
- DOI
  10.3390/membranes13080708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04974, KAKENHI-PROJECT-23K26511
[Journal Article] Direct observation of 890 ns dynamics of carbon black and polybutadiene in rubber materials using diffracted x-ray blinking2023
- Author(s)
  Kuramochi Masahiro、Kirkwood Henry J.、Koliyadu Jayanath C. P.、Letrun Romain、de Wijn Raphael、Kim Chan、Masui Tomomi、Mio Kazuhiro、Arai Tatsuya、Sekiguchi Hiroshi、Kishimoto Hiroyuki、Mancuso Adrian P.、Sato Tokushi、Sasaki Yuji C.
- Journal Title
  
  Applied Physics Letters
  
  Volume: 123 Issue: 10 Pages: 101601-101601
- DOI
  10.1063/5.0157359
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26511
[Journal Article] Diffracted X-ray Tracking using Time of Arrival Imaging on Timepix2022
- Author(s)
  関口博史, 青山光輝, 佐々木裕次
- Journal Title
  
  SPring-8/SACLA Research Report
  
  Volume: 10 Issue: 4 Pages: 350-353
- DOI
  10.18957/rr.10.4.350
- ISSN
  2187-6886
- Year and Date
  2022-08-31
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00324
[Journal Article] Protein large-scale motions revealed by quantum beams: A new era in understanding protein dynamics2022
- Author(s)
  Naoki Yamamoto, Rintaro Inoue, Ikuo Kurisaki, Tatsuhito Matsuo, Yuki Hishikawa, Wenyang Zhao, Hiroshi Sekiguchi
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 19 Issue: 0 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v19.0035
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00324, KAKENHI-PROJECT-21J10039
[Journal Article] Electric-Field-Induced Phase Transition and Crystal Structural Change of the Oriented Poly(vinylidene Fluoride) β Form as Clarified by the <i>In Situ</i> Synchrotron Wide-Angle X-ray Diffraction Measurement2022
- Author(s)
  Tashiro Kohji、Yamamoto Hiroko、Kummara Sreenivas、Tahara Daisuke、Aoyama Kouki、Sekiguchi Hiroshi
- Journal Title
  
  Macromolecules
  
  Volume: 55 Issue: 15 Pages: 6644-6660
- DOI
  10.1021/acs.macromol.2c01015
- Data Source
  KAKENHI-PROJECT-23K23419
[Journal Article] Diffracted X-ray blinking tracks single protein motions2018
- Author(s)
  Sekiguchi, H., Kuramochi, M., Ikesaki, K., Okamura, Y., Yoshimura, K., Matsubara, K., Chang, J. W., Ohta, N., Kubo, T., Mio, K., Suzuki, Y., Chavas, L. M., & Sasaki, Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1709-1709
- DOI
  10.1038/s41598-018-35468-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06945, KAKENHI-PUBLICLY-17H05539, KAKENHI-PLANNED-26105005, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] Time-Resolved Measurement of the ATP-Dependent Motion of the Group II Chaperonin by Diffracted Electron Tracking2018
- Author(s)
  Naoki Ogawa, Yohei Y. Yamamoto, Keisuke Abe, Hiroshi Sekiguchi, Yuji Y. Sasaki, Akira Ishikawa, Judith Frydman, Masafumi Yohda
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 4 Pages: 950-950
- DOI
  10.3390/ijms19040950
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00753, KAKENHI-PROJECT-16H04572, KAKENHI-PLANNED-26105005, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] DNA-binding induced conformational change of c-Myb R2R3 analyzed using diffracted X-ray tracking2018
- Author(s)
  Hosoe Yuhi、Inaba Satomi、Sekiguchi Hiroshi、Sasaki Yuji C.、Oda Masayuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 503 Issue: 1 Pages: 338-343
- DOI
  10.1016/j.bbrc.2018.06.025
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26105005, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] X-ray observations of single bio-supramolecular photochirogenesis2018
- Author(s)
  Chang Jaewon、Nishijima Masaki、Sekiguchi Hiroshi、Ichiyanagi Kohei、Kuramochi Masahiro、Inoue Yoshihisa、Sasaki Yuji C.
- Journal Title
  
  Biophysical Chemistry
  
  Volume: 242 Pages: 1-5
- DOI
  10.1016/j.bpc.2018.07.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26105005, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] Progressing of 3D Protein Structure and Dynamics Measurements2018
- Author(s)
  Ayana Sato-Tomita, Hiroshi Sekiguchi, Yuji C. Sasaki
- Journal Title
  
  Journal of the Physical Society of Japan
  
  Volume: 87 Issue: 6 Pages: 061015-061015
- DOI
  10.7566/jpsj.87.061015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06372, KAKENHI-PLANNED-26105005, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] Nanoscale Dynamics of Protein Assembly Networks in Supersaturated Solutions2017
- Author(s)
  Matsushita Y.、Sekiguchi H.、Wong C. Jae、Nishijima M.、Ikezaki K.、Hamada D.、Goto Y.、Sasaki Y. C.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 13883-13883
- DOI
  10.1038/s41598-017-14022-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21719, KAKENHI-PLANNED-17H06352, KAKENHI-ORGANIZER-26105001, KAKENHI-PLANNED-26105005, KAKENHI-PROJECT-15H04362
[Journal Article] First observation of metal ion-induced structural fluctuations of α-helical peptides by using diffracted X-ray tracking2017
- Author(s)
  Usui Daiki、Inaba Satomi、Sekiguchi Hiroshi、Sasaki Yuji C.、Tanaka Toshiki、Oda Masayuki
- Journal Title
  
  Biophysical Chemistry
  
  Volume: 228 Pages: 81-86
- DOI
  10.1016/j.bpc.2017.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21719, KAKENHI-ORGANIZER-26105001, KAKENHI-PLANNED-26105005
[Journal Article] Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC2017
- Author(s)
  Yohei Y. YAMAMOTO, Yuko UNO, Eiryo SHA, Kentaro IKEGAMI, Noriyuki ISHII, Naoshi DOHMAE, Hiroshi SEKIGUCHI, Yuji C. SASAKI, Masafumi YOHDA
- Journal Title
  
  PLOS ONE
  
  Volume: 12(5) Issue: 5 Pages: 0176054-0176054
- DOI
  10.1371/journal.pone.0176054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J08261, KAKENHI-INTERNATIONAL-15K21719, KAKENHI-PUBLICLY-16H00753, KAKENHI-ORGANIZER-26105001, KAKENHI-PLANNED-26105005, KAKENHI-PROJECT-16H04572
[Journal Article] Single Molecular Motions of MHC Class II Rely on Bound Peptides2015
- Author(s)
  Haruo Kozono, Yufuku Matsushita, Naoki Ogawa, Yuko Kozono, Toshihiro Miyabe, Hiroshi Sekiguchi, Kouhei Ichiyanagi, Noriaki Okimoto Makoto Taiji, Osami Kanagawa, and Yuji C Sasaki
- Journal Title
  
  Biophysical Journal
  
  Volume: 108 Issue: 2 Pages: 350-359
- DOI
  10.1016/j.bpj.2014.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J07839, KAKENHI-ORGANIZER-26105001, KAKENHI-PLANNED-26105005
[Journal Article] Time-resolved X-ray tracking of expansion and compression dynamics in supersaturating ion-networks2015
- Author(s)
  Y. Matsushita, H. Sekiguchi, N. Ohta, K. Ichiyanagi, K. Ikezaki, Y. Goto, Y. C. Sasaki
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 17647-17647
- DOI
  10.1038/srep17647
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-26105001, KAKENHI-PLANNED-26105005, KAKENHI-PROJECT-14J07839
[Journal Article] X線回折動画からのタンパク質１分子内部動態計測2014
- Author(s)
  佐々木裕次、一柳光平、関口博史
- Journal Title
  
  PF News
  
  Volume: 31 Pages: 15-21
- Data Source
  KAKENHI-PROJECT-24770147
[Journal Article] X線回折動画からのタンパク質1分子内部動態計測2014
- Author(s)
  佐々木裕次, 一柳光平, 関口博史
- Journal Title
  
  PF News
  
  Volume: Vol. 31 No.4 Pages: 15-21
- Data Source
  KAKENHI-PROJECT-24770147
[Journal Article] Inter-Ring Communication Is Dispensable in the Reaction Cycle of Group II Chaperonins.2014
- Author(s)
  Yamamoto YY, Abe Y, Moriya K, Arita M, Noguchi K, Ishii N, Sekiguchi H, Sasaki YC, Yohda M.
- Journal Title
  
  J Mol Biol.
  
  Volume: 426 Issue: 14 Pages: 2667-2678
- DOI
  10.1016/j.jmb.2014.05.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370064
[Journal Article] ATP dependent rotational motion of group II chaperonin observed by X-ray single molecule tracking2013
- Author(s)
  Hiroshi Sekiguchi, Ayumi Nakagawa, Kazuki Moriya, Koki Makabe, Kouhei Ichiyanagi, Shunsuke Nozawa, Tokushi Sato, Shin-ichi Adachi, Kunihiro Kuwajima, Masafumi Yohda and Yuji C. Sasaki
- Journal Title
  
  PLOS ONE
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241032
[Journal Article] ATP dependent rotational motion of group II chaperonin observed by X-ray single molecule tracking2013
- Author(s)
  H. Sekiguchi, A. Nakagawa, K. Moriya, K. Makabe, K. Ichiyanagi, S. Nozawa, T. Sato, S. Adachi, K. Kuwajima, M. Yohda and Y. C. Sasaki
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770147
[Journal Article] ATP dependent rotational motion of group II chaperonin observed by X-ray single molecule tracking.2013
- Author(s)
  Sekiguchi H, Nakagawa A, Moriya K, Makabe K, Ichiyanagi K, Nozawa S, Sato T, Adachi S, Kuwajima K, Yohda M, Sasaki YC.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 5 Pages: e64176-e64176
- DOI
  10.1371/journal.pone.0064176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24370064, KAKENHI-PROJECT-25440075
[Journal Article] Forced Extension of delipidated red blood cell cytoskeleton with little indication of spectrin unfolding2012
- Author(s)
  Afrin R, Nakaji M, Sekiguchi H, Lee D, Kishimoto K, Ikai A
- Journal Title
  
  Cytoskeleton
  
  Volume: 69巻 Issue: 2 Pages: 101-112
- DOI
  10.1002/cm.21001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0418, KAKENHI-PROJECT-22510122
[Journal Article] Nonlinear displacement of ventral stress fibers under externally applied lateral force by an atomic force microscope2011
- Author(s)
  Hakari T, Sekiguchi H, Osada T, Kishimoto K, Afrin R, Ikai A
- Journal Title
  
  Cytoskeleton
  
  Volume: 68巻 Issue: 11 Pages: 628-638
- DOI
  10.1002/cm.20537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0418, KAKENHI-PROJECT-22510122
[Journal Article] Direct detection of cellular adaptation to local cyclic stretching at the single cell level by atomic force microscopy2011
- Author(s)
  Watanabe-Nakayama T, Machida S, Harada I, Sekiguchi H, Afrin R, Ikai A
- Journal Title
  
  Biophysical Journal
  
  Volume: 100巻 Pages: 564-572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0418
[Journal Article] Single molecular dynamic interactions between glycophorin A and lectin as probed by atomic force microscopy2009
- Author(s)
  Yan C, Yersin A, Afrin R, Sekiguchi H, Ikai A.
- Journal Title
  
  Biophys Chem 144
  
  Pages: 72-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0418
[Journal Article] Pulling and Pushing Protein Molecules by AFM2007
- Author(s)
  Ikai, A., Afrin, R., H.Sekiguchi
- Journal Title
  
  Current Nanoscience 3
  
  Pages: 17-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15101004
[Journal Article] Pulling and Pushing Protein Molecules by AFM2007
- Author(s)
  Ikai, A., Afrin R., and H. Sekiguchi
- Journal Title
  
  Current Nanoscience 3
  
  Pages: 17-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0418
[Journal Article] AFM analysis of interaction forces between bio molecules using ligand-functionalized polymers2006
- Author(s)
  Sekiguchi, H., Ikai, A., Hideo Arakawa, Shigeru Sugiyama
- Journal Title
  
  e-J. Surt. Sci. Nanotech. 4
  
  Pages: 149-154
- NAID
  130004673790
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15101004
[Journal Article] AFM analysis of interaction forces between bio-molecules using ligand-functionalized polymers2006
- Author(s)
  Sekiguchi, H., Ikai, A., Hideo Arakawa, Shigeru Sugiyama
- Journal Title
  
  e-J. Surf. Sci. Nanotech. 4
  
  Pages: 149-154
- NAID
  130004673790
- Data Source
  KAKENHI-PROJECT-15101004
[Journal Article] AFM analysis of interaction forces between bio-molecules using ligand-functionalized polymers2006
- Author(s)
  Sekiguchi, H., Ikai, A., Hideo Arakawa, Shigeru Sugiyama
- Journal Title
  
  e-J.Surf.Sci.Nanotech. 4
  
  Pages: 149-154
- NAID
  130004673790
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15101004
[Presentation] X-ray single molecule observations using SR and laboratory source2024
- Author(s)
  佐々木裕次、三尾和弘、関口博史
- Organizer
  Biophysical society 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26511
[Presentation] Allosteric transition dynamics in hemoglobin Reconsidered by Diffracted X-ray Tracking2022
- Author(s)
  関口博史,山本直樹,柴山修哉,佐々木裕次
- Organizer
  第60回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00324
[Presentation] Development of Advanced Diffracted X-Ray Tracking for Single Molecule Intra-Dynamics with Low Dose and Wide Angular Dynamic Range2018
- Author(s)
  H. Sekiguchi et al.
- Organizer
  Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26105005
[Presentation] DISSECTION OF THE ATP-DEPENDENT CONFORMATIONAL CHANGE CYCLE OF A GROUP II CHAPERONIN2015
- Author(s)
  Yohda M, Sekiguchi H,Nakagawa A, Yamamoto Y, Kuwajima K, Sasski YC
- Organizer
  The 3rd International Symposium on Dynamical Ordering of Biomolecular Systems for Creation of Integrated Functions
- Place of Presentation
  Nemuno sato, Shima
- Year and Date
  2015-01-11
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Single Molecule Motion Maps of Open and Desensitization States of Nicotinic Acetylcholine Receptors2014
- Author(s)
  H. Sekiguchi, M. Tokue, Y. Nishino, K. Ichiyanagi, N. Yagi, A. Miyazawa, T. Kubo, Y. C. Sasaki
- Organizer
  58th Annual Meeting of Biophysical Society
- Place of Presentation
  Moscone Center, San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] 超好熱性古細菌由来グループII型シャペロニンのリング内サブユニット間協調作用機構に関する研究2014
- Author(s)
  石黒直輝、有田真優乃、山本陽平、志村眞弘、佐々木裕次、関口博史、養王田正文
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Dissection of the ATP-dependent conformational change cycle of a group II chaperonin2014
- Author(s)
  Yohda M, Sekiguchi H,Nakagawa A, Yamamoto Y, Oka T, Kuwajima K, Sasski YC
- Organizer
  MOLECULAR CHAPERONES & STRESS RESPONSES
- Place of Presentation
  Cold Spring Harbor Laboratory, USA
- Year and Date
  2014-04-30
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] X線１分子追跡法から見えてきたタンパク質１分子内運動2014
- Author(s)
  関口博史
- Organizer
  第82回LSJセミナー
- Place of Presentation
  Stanford University, USA
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Dissection of the ATP-dependent conformational change cycle of group II chaperonin2014
- Author(s)
  Yohda M, Sekiguchi H,Nakagawa A, Yamamoto Y, Oka T, Kuwajima K, Sasski YC
- Organizer
  Japan-Italy Joint Symposium
- Place of Presentation
  東大寺ミュージアム、奈良
- Year and Date
  2014-11-06
- Invited
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] 超好熱性古細菌由来グループII型シャペロニンのリング内サブユニット間協調作用機構に関する研究2014
- Author(s)
  石黒直輝、有田真優乃、山本陽平、志村眞弘、佐々木裕次、関口博史、養王田正文
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜・横浜産貿ホール、横浜
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Cooperative Motion Analysis of group II chaperonin by X-ray Single Molecule Tracking2013
- Author(s)
  関口博史、山本陽平、有田真優乃、石黒直樹、一柳光平、養王田正文、八木直人、佐々木裕次
- Organizer
  第51回日本生物物理学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] 表面に分子修飾した金ナノ結晶の熱伝導プロセス2013
- Author(s)
  一柳光平、関口博史、野澤俊介、佐藤篤志、足立伸一、佐々木裕次
- Organizer
  第26回放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  名古屋大学
- Year and Date
  2013-01-13
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] タンパク質複合体・協同的運動の１分子解析2013
- Author(s)
  関口博史
- Organizer
  第26回放射光学会年会　放射光科学合同シンポジウム
- Place of Presentation
  名古屋大学　東山キャンパス
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] X線 / 電子線の水中単一ナノ結晶に対する放射圧とその応用2013
- Author(s)
  星指健太郎、関口博史、一柳光平、鈴木祥仁、八木直人、松尾龍人、太田昇、佐々木裕次
- Organizer
  第26回放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  名古屋大学
- Year and Date
  2013-01-13
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] Cooperative Motion of a Multi-subunit Protein Visualized by X-ray Single Molecule Tracking2013
- Author(s)
  H. Sekiguchi, Y. Yamamoto, A. Nakagawa, K. Moriya, M. Arita, K. Ichiyanagi, M. Yohda, N. Yagi and Y. C. Sasaki
- Organizer
  57th Annual Meeting of Biophysical Society
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] タンパク質複合体協同的運動の1分子解析2013
- Author(s)
  関口博史,山本陽平,有田真優乃,一柳光平野澤俊介,佐藤篤志,足立伸一,養王田正文,八木直人,佐々木裕次
- Organizer
  第26回放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  名古屋大学
- Year and Date
  2013-01-13
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] アセチルコリン受容体のマイクロ秒 1 分子計測2013
- Author(s)
  徳江真紀、関口博史、星指健太郎、小林寿珠子、Cai Weiyang、下山よしこ、西野有里、八木直人、太田昇、宮澤淳夫、久保泰、佐々木裕次
- Organizer
  第26回放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  名古屋大学
- Year and Date
  2013-01-14
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] タンパク質複合体・協同的運動の１分子解析2013
- Author(s)
  関口博史
- Organizer
  第26回放射光学会年会
- Place of Presentation
  名古屋大学
- Year and Date
  2013-01-12
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] 3D Micro-second X-ray Single Molecule Tracking of Nicotinic Acetylcholine Receptor with Picometer Accuracy2013
- Author(s)
  H. Sekiguchi (M. Tokue)
- Organizer
  57th Annual Meeting of Biophysical Society
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] 高速X線1分子追跡法による複合体タンパク質・ダイナミクス計測2013
- Author(s)
  関口博史
- Organizer
  京都府立大学生命物理化学セミナー「蛋白質の動的挙動解明に向けた革新的分析手法」
- Place of Presentation
  キャンパスプラザ京都第一会議室,京都市
- Year and Date
  2013-11-03
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Cooperative Motion of a Multi-subunit Protein Visualized by X-ray Single Molecule Tracking2013
- Author(s)
  関口博史
- Organizer
  57th Annual Meeting of Biophysical Society
- Place of Presentation
  Philadelphia
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] タンパク質複合体・協同的運動の１分子解析2013
- Author(s)
  関口博史
- Organizer
  第26回放射光学会年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Cooperative Motion of a Multi-subunit Protein Visualized by X-ray Single Molecule Tracking2013
- Author(s)
  H. Sekiguchi
- Organizer
  57th Annual Meeting of Biophysical Society
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] X 線一分子追跡法を用いた MHC 分子認識機構の解明2013
- Author(s)
  松下祐福 ,小園晴生 ,星指健太郎 ,一柳光平 ,関口博史 ,佐々木裕次
- Organizer
  第26回放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  名古屋大学
- Year and Date
  2013-01-14
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] 3D Micro-second X-ray Single Molecule Tracking of Nicotinic Acetylcholine Receptor with Picometer Accuracy2013
- Author(s)
  M. Tokue, K .Hoshisashi, H. Sekiguchi, N. Yagi, K. Ichiyanagi, Y. Nishino, A. Miyazawa, T. Kubo, Y. C. Sasaki
- Organizer
  57th Annual Meeting of Biophysical Society
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] タンパク質複合体・協同的運動の1分子解析2013
- Author(s)
  関口博史, 山本陽平, 有田真優乃, 一柳光平, 野澤俊介, 佐藤篤志, 足立伸一, 養王田正文, 八木直人, 佐々木裕次
- Organizer
  第26回放射光学会年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] グループII 型シャペロニンの1 分子内ダイナミクス計測2012
- Author(s)
  関口博史
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Dynamic structural and antigen binding analyses of antibody single-chain Fvs2012
- Author(s)
  田中裕介, 関口博史, 佐々木裕次 , 東隆親, 織田昌幸
- Organizer
  第50回生物物理学会年会
- Place of Presentation
  名古屋大学
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] Single Molecule Dynamics of Peptide/MHC Complex and T-cell Activations2012
- Author(s)
  H.Sekiguchi, K.Hoshisashi, N.Ogawa, H.Kozono, O.Kanagawa, Y.C.Sasaki
- Organizer
  5th International Symposium on Molecular Science of Fluctuations toward Biological Functions
- Place of Presentation
  東大寺総合文化センター
- Year and Date
  2012-01-07
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Chaperonin-Ring'sTwist Is Critical for Folding Activity ofDXT) for single molecule measurement of rotational motion in reaction with photoindissociated ATP2012
- Author(s)
  Hiroshi Sekiguchi
- Organizer
  Biophysical Society 56th annual meeting
- Place of Presentation
  サンディエゴアメリカ
- Year and Date
  2012-02-25
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] グループII 型シャペロニンの1 分子内ダイナミクス計測2012
- Author(s)
  関口博史
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] 超好熱性古細菌由来II型シャペロニンのリング内サブユニット間協調作用機構に関する研究2012
- Author(s)
  有田真優乃、守谷和騎、真壁幸樹、桑島邦博、佐々木裕次、関口博史、養王田正文
- Organizer
  第7回臨床ストレス応答学会大会
- Place of Presentation
  東京女子医科大学弥生記念講堂
- Year and Date
  2012-11-24
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Caged-ATPとパルスレーザーを組み合わせた光励起X線1分子計測法の開発2012
- Author(s)
  一柳光平、関口博史、野澤俊介、佐藤篤志、足立伸一、佐々木裕次
- Organizer
  第25回日本放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  鳥栖市民文化会館
- Year and Date
  2012-01-09
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] 超好熱性古細菌由来II型シャペロニンのリング内サブユニット間協調作用機構に関する研究2012
- Author(s)
  有田真優乃、守谷和騎、真壁幸樹、桑島邦博、佐々木裕次、関口博史、養王田正文
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] 循環置換型連結変異体によるII型シャペロニンヘテロリング複合体の構築と機能解析2012
- Author(s)
  山本陽平、阿部由寛、守谷和騎、阿部哲也、関口博史、佐々木裕次、養王田正文
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Cooperative Motion Analysis of group II chaperonin at Single-molecule Level using Diffracted X-ray Tracking2012
- Author(s)
  関口博史
- Organizer
  第50回生物物理学会年会
- Place of Presentation
  名古屋大学　東山キャンパス
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] グループII型シャペロニンの1分子内ダイナミクス計測2012
- Author(s)
  関口博史、中川あゆみ、守谷和騎、一柳光平、養王田正文、佐々木裕次
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Cooperative Motion Analysis of group II chaperonin at Single-molecule Level using Diffracted X-ray Tracking2012
- Author(s)
  関口博史
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Cooperativity analysis of multi-subunit proteins by 3D X-ray single molecule tracking2012
- Author(s)
  関口博史
- Organizer
  International workshop on 3D atomic imaging at nano-scale active sites in materials
- Place of Presentation
  東京大学柏キャンパスメディアホール
- Year and Date
  2012-08-06
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Cooperativity analysis of multi-subunit proteins by 3D X-ray single molecule tracking2012
- Author(s)
  関口博史
- Organizer
  International workshop on 3D atomic imaging at nano-scale active sites in materials
- Place of Presentation
  東京大学柏メディアホール
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Multi-dimensional High-speed Single Molecular Observations from Labeled Gold-nanocrystal using X-rays andElectron2012
- Author(s)
  Y. SASAKI, H. Sekiguchi, K. Ichyanagi, K. Hoshisashi, N. Yagi
- Organizer
  GOLD2012
- Place of Presentation
  京王プラザホテル
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] シャペロニンタンパク質分子の１分子ダイナミクス機能計測2012
- Author(s)
  関口博史
- Organizer
  第１回東大新領域・KEK連携教育シンポジウム
- Place of Presentation
  高エネルギー加速器研究機構
- Year and Date
  2012-09-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Cooperativity analysis of multi-subunit proteins by 3D X-ray single molecule tracking2012
- Author(s)
  H. Sekiguchi, Y. Yamamoto, M. Ariga, Y. Nishino, K. Ichiyanagi, N. Yagi, A. Miyazawa, M. Yohda, Y. C. Sasaki
- Organizer
  International workshop on 3D atomic imaging at nano-scale active sites in materials (3D-AINAS 2012)
- Place of Presentation
  Media hall in Kashiwa library, University of Tokyo, Chiba, JAPAN
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Cooperative Motion Analyses of Multi-subunit Proteins Visualized by X-ray Single Molecule Tracking2012
- Author(s)
  関口博史
- Organizer
  The 5th International Symposium on “Molecular Science of Fluctuations toward Biological Functions
- Place of Presentation
  京都テルサ
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] グループII型シャペロニンアシンメトリックリング複合体構築とリング間協調作用の解析2012
- Author(s)
  山本陽平、阿部由寛、守谷和騎、阿部哲也、関口博史、佐々木裕次、養工田正文
- Organizer
  第7回臨床ストレス応答学会大会
- Place of Presentation
  東京女子医科大学弥生記念講堂
- Year and Date
  2012-11-24
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] X線1分子追跡法による11型シャペロニン協同性評価2012
- Author(s)
  Hiroshi Sekiguchi, Ayumi Nakagawa, Kazuki Moriya, Mayuno Arita, Yohei Yamamoto, Kohei Ichiyanagi, Masafumi Yohda, Naoto Yagi, Yuji Sakaki
- Organizer
  日本生物物理学会第50回年会
- Place of Presentation
  名古屋大学東山キャンパス
- Year and Date
  2012-09-23
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] 超好熱性古細菌由来II型シャペロニンのリング内サブユニット間協調作用機構に関する研究2012
- Author(s)
  有田真優乃、守谷和騎、真壁幸樹、桑島邦博, 佐々木裕次、関口博史、養王田正文
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Cooperative Motion Analysis of group II Chaperonin at Single-molecule Level using Diffracted X-ray Tracking X 線1分子追跡法による II 型シャペロニン協同性評価2012
- Author(s)
  関口博史 , 中川あゆみ, 守谷和騎, 有田真優乃, 山本陽平, 一柳光平, 養王田正文 , 八木直人 , 佐々木裕次
- Organizer
  第50回生物物理学会年会
- Place of Presentation
  名古屋大学
- Year and Date
  2012-09-23
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] 高速X線１分子追跡法による複合体タンパク質・ダイナミクス計測2012
- Author(s)
  関口博史
- Organizer
  京都府立大学生命物理化学セミナー
- Place of Presentation
  キャンパスプラザ京都第一会議室
- Year and Date
  2012-11-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Development of Diffracted X-ray Tracking measurement system using various wide-band energy X-ray sources 白色X線源を用いたX線1分子計測法の開発2012
- Author(s)
  一柳光平, 関口博史, 星野真人, 梶原健太郎, 野澤俊介, 佐藤篤志, 足立伸一, 八木直人, 佐々木裕次
- Organizer
  第50回生物物理学会年会
- Place of Presentation
  名古屋大学
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] 複合体タンパク質・分子内運動の高速１分子計測2012
- Author(s)
  関口博史
- Organizer
  新学術領域「揺らぎと生体機能」「水和とATP」合同公開シンポジウム
- Place of Presentation
  大阪ガーデンパレス
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Chaperonin-ring's Twist is Critical for Folding Activity of Group II Chaperonin2012
- Author(s)
  H.Sekiguchi, A.Nakagawa, K.Moriya, M.Yohda, K.Ichiyanagi, Y.C.Sasaki
- Organizer
  56th Annual Meeting of Biophysical Society
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2012-02-26
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] 複合体タンパク質・分子内運動の高速1分子計測2012
- Author(s)
  関口博史, 山本陽平, 有田真優乃, 西野有里, 宮澤淳夫, 養王田正文, 八木直人, 佐々木裕次
- Organizer
  新学術領域「揺らぎと生体機能」「水和とATP」合同公開シンポジウム「ゆらぎと水−生命のエネルギーと機能の分子機構を探る」
- Place of Presentation
  大阪ガーデンパレス
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] Cooperative Motion Analysis of group II chaperonin at Single-molecule Level using Diffracted X-ray Tracking2012
- Author(s)
  関口博史
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] 二つの回転軸から眺めるタンパク質の機能的1分子内運動2012
- Author(s)
  関口博史
- Organizer
  新世代研究所バイオ単分子研究会
- Place of Presentation
  鴨川館/千葉県(招待講演)
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] X線1分子追跡法によるグループII型シャペロニンのねじれ運動解析2011
- Author(s)
  関口博史, 中川あゆみ, 守谷和騎, 養王田正文, 佐々木裕次
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  大阪ホテル阪急エキスポパーク
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Torsional Motion Analysis of Group II Chaperon in Using Diffracted X-ray Tracking2011
- Author(s)
  H.Sekiguchi, A.Nakagawa, K.Moriya, M.Yohda, K.Ichiyanagi, Y.C.Sasaki
- Organizer
  8th European Biophysics Congress
- Place of Presentation
  ELTE University Congress Center, Budapest, Hungary
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] X線1分子追跡法によるII型シャペロニンの高精度動態解析2011
- Author(s)
  関口博史,中川あゆみ,守谷和騎,養王田正文,佐々木裕次
- Organizer
  第49回日本生物物理学会年会
- Place of Presentation
  兵庫県立大学
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] X線1分子追跡法によるII型シャペロニンの高精度動態解析2011
- Author(s)
  関口博史, 中川あゆみ, 守谷和騎, 養王田正文, 佐々木裕次
- Organizer
  第49回日本生物物理学会年会
- Place of Presentation
  兵庫県立大学姫路書写キャンパス
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] X線1分子追跡法で迫るタンパク質分子の機能発現機構2011
- Author(s)
  関口博史
- Organizer
  第5回学融合ビジュアライゼーションシンポジウム
- Place of Presentation
  東京大学柏図書館メディアホール
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Torsional Motion Analysis of Group II Chaperonin at Single Molecular Level Using Diffracted X-ray Tracking2011
- Author(s)
  H.Sekiguchi, A.Nakagawa, K.Moriya, M.Yohda, Y.C.Sasaki
- Organizer
  25th Anniversary Symposium of the Protein Society
- Place of Presentation
  Boston Marriott Copley Place, MA, USA
- Year and Date
  2011-07-24
- Data Source
  KAKENHI-PUBLICLY-23107706
[Presentation] Direct Detection OF Tension Recovery After Local Stretching of Cell Surface2010
- Author(s)
  Takahiro W. Nakayama, Shin-ichi Machida, Ichiro Harada, Hiroshi Sekiguchi, Rehana Afrin, Atsushi Ikai
- Organizer
  American Biophysical Society 54th Annual Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] Torsional Motion Analysis of Group II Chaperonin Using Diffracted X-ray Tracking2010
- Author(s)
  Hiroshi Sekiguchi
- Organizer
  8th European Biophysics Congress
- Place of Presentation
  ブダペストハンガリー
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22241032
[Presentation] AFMによるタンパク質分子の圧縮:実験とシミュレーション2008
- Author(s)
  関口博史
- Organizer
  日本顕微鏡学会第64回学術講演会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] AFM力学測定の生命科学への応用:精度良い測定に向けて2008
- Author(s)
  関口博史
- Organizer
  第28回表面科学学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] 溶液中環境下でのAFMによるタンパク質力学計測2008
- Author(s)
  関口博史
- Organizer
  日本顕微鏡学会走査型プローブ顕微鏡分科会平成19年度研究会
- Place of Presentation
  京都日本
- Year and Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] タンパク質の表面吸着と破壊2008
- Author(s)
  関口博史
- Organizer
  日本表面科学会第3回ソフトナノテクノロジー研究部会
- Place of Presentation
  東京日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] Nano-indentation of Single Protein Investigated by Atomic Force Microscopy2008
- Author(s)
  Hiroshi Sekiguchi
- Organizer
  Protein Research International Symposium on "New Approaches to Complexity of Protein Dynamics by Single Molecule Measurements: Experiments and Theories
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] Nano-indentation of Single Protein Investigated by Atomic Force Microscopy2008
- Author(s)
  H. Sekiguchi, Y. Mori, A. Ikai
- Organizer
  Protein Research International Symposium on "New Approaches to Complexity of Protein Dynamics by Single Molecule Measurements: Experiments and Theories"
- Place of Presentation
  Icho-Kaikai, Osaka univ
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] High sensitive detection of proteins using gel electrophoresis and atomic force microscopy2008
- Author(s)
  Hiroshi Sekiguchi
- Organizer
  10th International Scanning Probe Microscopy Conference
- Place of Presentation
  Seattle米国
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] AFMによる生体分子間相互作用力測定2008
- Author(s)
  関口博史
- Organizer
  財団法人新世代研究所バイオSPM研究会
- Place of Presentation
  新潟日本
- Year and Date
  2008-03-14
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] Applications of AFM Force Measurement for Life-science Field2008
- Author(s)
  Hiroshi Sekiguchi
- Organizer
  日本生物物理学会第46会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] タンパク質分子力学の実験と分子動力学シミュレーション2008
- Author(s)
  関口博史, 田上勝規, 森泰啓, 塚田捷, 猪飼篤
- Organizer
  ナノプローブテクノロジー第167委員会第49回研究会
- Place of Presentation
  東京日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] AFM analysis of interaction forces between bio-molecules using ligand-functionalized polymers2007
- Author(s)
  関口博史, 猪飼篤, 荒川秀雄, 杉山滋
- Organizer
  第27回表面科学講演大会
- Place of Presentation
  東京日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] AFMによるフェリチン分子の物性計測2007
- Author(s)
  関口博史, 森泰啓, 猪飼篤
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  横浜日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] フェリチン分子の圧縮計測:実験とシミュレーション2007
- Author(s)
  関口博史, 田上勝規, 森泰啓, 塚田捷, 猪飼篤
- Organizer
  平成19年度日本顕微鏡学会SPM研究部会第10回研究会
- Place of Presentation
  湯沢日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] 赤血球における細胞骨格の弾性研究2007
- Author(s)
  中路雅登, 関口博史, レハナアフリン, 猪飼篤
- Organizer
  第27回表面科学講演大会
- Place of Presentation
  東京日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] AFMによるフェリチン分子の押し込み力学測定2007
- Author(s)
  関口博史, 森泰啓, 猪飼篤
- Organizer
  第27回表面科学講演大会
- Place of Presentation
  東京日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] 電気泳動法とAFM での力学測定によるタンパク質の高感度検出の試み2007
- Author(s)
  日高敦, 志賀嘉仁, 関口博史, 猪飼篤, 長田俊哉
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] 赤血球における細胞骨格の力学的研究2007
- Author(s)
  中路雅登, 関口博史, Afrin Rehana, 猪飼篤
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  横浜日本
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] Nano-mechanics of Single Protein Using Atomic Force Microscopy2007
- Author(s)
  H. Sekiguchi, Y. Mori, and A. Ikai
- Organizer
  21st Annual Symposium of The Protein Society
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-19GS0418
[Presentation] Cooperative Motion Analysis of group II chaperonin by X-ray Single Molecule Tracking
- Author(s)
  Hiroshi Sekiguchi、Yohei Yamamoto、Mayuno Arinta、Naoki Ishiguro、Kouhei Ichiyanagi、Masafumi Yohda、Naoto Yagi、Yuji Sasaki
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] グループII型シャペロニンアシンメトリックリング複合体の構築とリング間協調作用
- Author(s)
  山本陽平、阿部由貴、守谷和騎、阿部哲也、関口博史、佐々木裕次、養王田正文
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館、鳥取市
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] グループII型シャペロニンにおけるリング間協調作用機構の解明
- Author(s)
  山本陽平、石井則行、関口博史、佐々木裕次、養王田正文
- Organizer
  第8回臨床ストレス応答学会大会
- Place of Presentation
  信州大学医学部、松本市
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] シャペロニンタンパク質分子の１分子ダイナミクス機能計測
- Author(s)
  関口博史
- Organizer
  第１回東大新領域・KEK連携教育シンポジウム
- Place of Presentation
  高エネルギー加速器研究機構
- Invited
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] グループII型シャペロニンアシンメトリックリング複合体の構築とリング間協調作用
- Author(s)
  山本陽平、阿部由寛、守谷和騎、阿部哲也、関口博史、佐々木裕次、養王田正文
- Organizer
  第65回日本生物工学会大会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Conformational change cycle group II chaperonin revealed by kinetic study and diffracted X-ray trackin
- Author(s)
  Masafumi Yohda、Hiroshi Sekiguchi、Ayumi Nakagawa、Kazuki Moriya、Toshihiko Oka、Koki Makabe、Kunihito Kuwajima、Yuji Sasaki
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館、鳥取市
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] Inter-ring communication is dispensable in the reaction cycle of group II chaperonins
- Author(s)
  Yohei Yamamoto、Noriyuki Ishii、 Hiroshi Sekiguchi、Yuji C. Sasaki、Masafumi Yohda
- Organizer
  理数学生育成支援事業」独創的発想に富む科学者育成プログラム　国際ミニシンポジウム
- Place of Presentation
  秋田ビューホテル
- Data Source
  KAKENHI-PROJECT-24370064
[Presentation] 高速X線１分子追跡法による複合体タンパク質・ダイナミクス計測
- Author(s)
  関口博史
- Organizer
  京都府立大学生命物理化学セミナー
- Place of Presentation
  キャンパスプラザ京都
- Invited
- Data Source
  KAKENHI-PROJECT-24770147
[Presentation] グループII型シャペロニンアシンメトリックリング複合体の構築とリング間協調作用解析
- Author(s)
  山本陽平、阿部由寛、守谷和騎、阿部哲也、関口博史、佐々木裕次、養王田正文
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24370064
[]

1. SASAKI Yuji (30344401)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
2. Masayuki Oda (20318231)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. IKAI Atsushi (50011713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
4. OSADA Toshiya (00201997)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. ICHIYANAGI Kohei (70435618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
6. 柴山修哉 (20196439)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. KISHIMOTO Kikuo (30111652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. OHTANI Hiroyuki (80203826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. AFRIN Rehana (70447556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. TAGAMI Katsunor (40361571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. YAGI Naoto (80133940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. YOHDA MASAFUMI (50250105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
13. 宮澤淳夫 (60247252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 久保泰 (10178030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 荒川秀雄 (80211704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. 沼本修孝 (20378582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 神谷成敏 (80420462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宮ノ入洋平 (80547521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 田代孝二 (60171691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 山下義裕 (00275166)

# of Collaborated Projects: 1 results

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21. 三尾和弘 (40470041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 山下隼人 (10595440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 倉持昌弘 (60805810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. MAKABE Koki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. NOZAWA Shunsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 松下智裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 稲垣英利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 富田文菜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sekiguchi Hiroshi 関口 博史

SEKIGUCHI Hiroshi 関口 博史

関口 博史 セキグチ ヒロシ

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Multiscale motion analysis of membrane proteins at neuromuscular junctionPrincipal Investigator

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高速１分子動態計測による膜タンパク質機能発現機構の解明Principal Investigator

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[Book] Advances in Chemical Physics : Single Molecule Biophysics : Experiments and Theory(Eds : T. Komatsuzaki et al.)2011

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[Book] Applied Scanning Probe Method IX (B. Bhushan ed.)2008

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[Journal Article] Real-time tilting and twisting motions of ligand-bound states of α7 nicotinic acetylcholine receptor2024

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Sekiguchi Hiroshi 関口博史

SEKIGUCHI Hiroshi 関口博史

関口博史セキグチヒロシ