KAWASHITA Norihito 川下理日人

… Alternative Names

川下理日人カワシタノリヒト

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Researcher Number	00423111
Other IDs
Affiliation (Current)	2025: 近畿大学, 理工学部, 准教授
Affiliation (based on the past Project Information) *help	2022: 近畿大学, 理工学部, 准教授 2018 – 2021: 近畿大学, 理工学部, 講師 2015 – 2019: 大阪大学, 薬学研究科, 助教 2015: 大阪大学, 大学院薬学研究科, 助教 2011 – 2015: 大阪大学, 薬学研究科(研究院), 助教 … More 2012: 大阪大学, 大学院・薬学研究科, 助教 2009 – 2010: 大阪大学, 薬学研究科, 助教 2007: Osaka University, 薬学研究科, 助教 2006: 大阪大学, 微生物病研究所, 特任助手 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Mathematical Sciences in Search of New Cooperation / Drug development chemistry / Physical pharmacy / Medical pharmacy
Keywords	Principal Investigator HIV / ドッキングシミュレーション / インフルエンザ / ホモロジーモデリング / エンタルピー / 阻害剤 / 相互作用エネルギー / 相互作用 / 分子動力学計算 / 蛋白質間相互作用 … More / 活性予測 / 機械学習 / フラグメント分子軌道法 / 自由エネルギー / エントロピー / 分子設計 / 抗ウイルス薬 / 配列解析 / 薬剤耐性 / 感染症 / ウイルス / 変異 / ドッキングスタディ / シミュレーション / 抗ウイルス剤 / 蛋白質 … More Except Principal Investigator ロジスティック回帰 / アノテーション / 次世代型遺伝医療 / 遺伝医療 / 遺伝性消化管腫瘍 / コンパニオン診断 / 発症前診断 / サーベイランス / がんサーベイランス / 遺伝学的検査 / バイオインフォマティクス / 遺伝カウンセリング / 二次的所見 / がんゲノム医療 / 次世代シークエンシング / リー・フラウメニ症候群 / 家族性腺腫性ポリポーシス / リンチ症候群 / 遺伝性腫瘍 / グレブナー基底 / 医薬品有害事象 / Random Forest / JADER / 重大副作用 / 多数決法 / ランダムフォレスト / サポートベクターマシン / 副作用予測 / 多変量解析 / ROC曲線 / AI / 重篤希少有害事象 / マルチラベル学習 / スティーブンス・ジョンソン症候群 / 悪性症候群 / 化学記述子 / Stacking / ATCコード / 機械学習 / 有害事象 / アンチセンス医薬 / バイオコンジュゲート / アンチセンス核酸 / ゲノム創薬 / 核酸医薬 / PCLS / バリマックス変換 / PLS / 主成分回帰 / 主成分分析 / 医薬学統計 / 説明変数 / 加水分解性予測 / 偶然の相関 / 判別分析 / 回帰分析 / 環境化学 / 加水分解 / 正則化 / Data Mining / Classification / Hydrolyzability / Elastic Net / Ridge Regression / L2 Regularization / L1 Regularization / Chance Correlation / ケモメトリックス / 定量的構造活性相関モデル / Stevens-Johnson症候群 / 中毒性表皮壊死症 / 皮膚粘膜眼症候群 / 相関ルール / ノンパラメトリック回帰 / データマイニング / シグナル検出 / Stevens-Johnson 症候群 / AERS Less

Progressive research on genetic testing for hereditary gastrointestinal tumors and fundamental research on next-generation medical genetics
- Principal Investigator
  
  Tamura Kazuo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kindai University
Development of novel free energy change prediction method independent of entropy changePrincipal Investigator
- Principal Investigator
  
  Kawashita Norihito
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kindai University
Modeling for Prediction of Serious Adverse Events Probabilities of Drug Candidates
- Principal Investigator
  
  TAKAGI Tatsuya
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Mathematical Sciences in Search of New Cooperation
- Research Institution
  Osaka University
An approach for eliminating chance correlations and its application to pharmaceutical data.
- Principal Investigator
  
  Takagi Tatsuya
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University
Deverlopment of in silico drug resistance evaluation based on the target protein structuresPrincipal Investigator
- Principal Investigator
  
  Kawashita Norihito
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University
Development of platform technologies for antisense oligonucleotide-based therapeutics by a combination of nucleic acids chemistry and information sciences
- Principal Investigator
  
  Satoshi Obika
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University
Study on Adverse Events ofDrugs usingData Mining
- Principal Investigator
  
  TAKAGI Tatsuya
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University
量子化学・分子力学的手法を利用した抗ウイルス剤開発指向ドッキングスタディPrincipal Investigator
- Principal Investigator
  
  川下理日人
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University

All 2022 2021 2020 2019 2018 2016 2015 2014 2013 2010 2009 Other

All Journal Article Presentation

[Journal Article] Protein-ligand binding affinity prediction of cyclin‐dependent kinase‐2 inhibitors by dynamically averaged fragment molecular orbital‐based interaction energy2022
- Author(s)
  Takaba Kenichiro、Watanabe Chiduru、Tokuhisa Atsushi、Akinaga Yoshinobu、Ma Biao、Kanada Ryo、Araki Mitsugu、Okuno Yasushi、Kawashima Yusuke、Moriwaki Hirotomo、Kawashita Norihito、Honma Teruki、Fukuzawa Kaori、Tanaka Shigenori
- Journal Title
  
  Journal of Computational Chemistry
  
  Volume: 43 Issue: 20 Pages: 1362-1371
- DOI
  10.1002/jcc.26940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06098, KAKENHI-PROJECT-18K06615
[Journal Article] FMODB: The World’s First Database of Quantum Mechanical Calculations for Biomacromolecules Based on the Fragment Molecular Orbital Method2021
- Author(s)
  Daisuke Takaya, Chiduru Watanabe, Shunpei Nagase, Kikuko Kamisaka, Yoshio Okiyama, Hirotomo Moriwaki, Hitomi Yuki, Tomohiro Sato, Noriyuki Kurita, Yoichiro Yagi, Tatsuya Takagi, Norihito Kawashita, Kenichiro Takaba, Tomonaga Ozawa, Midori Takimoto-Kamimura, Shigenori Tanaka, Kaori Fukuzawa, and Teruki Honma
- Journal Title
  
  J. Chem. Inf. Model.
  
  Volume: 61 Issue: 2 Pages: 777-794
- DOI
  10.1021/acs.jcim.0c01062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06615, KAKENHI-PROJECT-18K03825, KAKENHI-PROJECT-18K06619, KAKENHI-PLANNED-17H06353
[Journal Article] Intermolecular Interaction Analyses on SARS-CoV-2 Spike Protein Receptor Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor-Blocking Antibody/Peptide Using Fragment Molecular Orbital Calculation2021
- Author(s)
  Kazuki Watanabe, Chiduru Watanabe, Teruki Honma, Yu-Shi Tian, Yusuke Kawashima, Norihito Kawashita, Tatsuya Takagi, Kaori Fukuzawa
- Journal Title
  
  J. Phys. Chem. Lett.
  
  Volume: 12 Issue: 16 Pages: 4059-4066
- DOI
  10.1021/acs.jpclett.1c00663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06615, KAKENHI-PROJECT-20K06987
[Journal Article] Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome.2019
- Author(s)
  Tamura K, Kaneda M, Futagawa M, Takeshita M, Kim S, Nakama M, Kawashita N, Tatsumi-Miyajima J.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 24 Issue: 9 Pages: 999-1011
- DOI
  10.1007/s10147-019-01494-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07763
[Journal Article] 認定遺伝カウンセラー®の雇用に対する検査会社の視点2019
- Author(s)
  仲間美奈, 白山大揮, 田村和朗, 川下理日人, 萩原央記, 巽純子, 南武志
- Journal Title
  
  日本遺伝カウンセリング学会誌
  
  Volume: 40 Pages: 85-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07763
[Journal Article] A practical estimation method for analyzing adverse drug reactions using data mining2013
- Author(s)
  Y. Shirakuni, K. Okamoto, E. Uejima, S. Inui, J. Takahara, T. Ohgaru, H. Yamasaki, Y.-S. Tian, N. Kawashita, R. Inoue, T. Yasunaga, T. Takagi
- Journal Title
  
  Therapeutic Innovation & Regulatory Science
  
  Volume: 47(2) Pages: 235-241
- Data Source
  KAKENHI-PROJECT-21590157
[Journal Article] Signal Detection of Drug Complications Applying Association Rule Learning for Stevens-Johnson Syndrome2009
- Author(s)
  Y. Shirakuni, K. Okamoto, N. Kawashita, T. Yasunaga, T. Takagi
- Journal Title
  
  J. Comput. Aided Chem.
  
  Volume: 10 Pages: 118-127
- DOI
  10.2751/jcac.10.118
- NAID
  130004927274
- ISSN
  1345-8647
- Language
  English
- Data Source
  KAKENHI-PROJECT-21590157
[Presentation] Analysis of interaction energies for SMAD4 variants by computational science2022
- Author(s)
  Kazuma Harada, Ai Itagaki, Norihito Kawashita
- Organizer
  CBI学会2022大会
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] Interaction analysis of 14-3-3 and p53 using fragment molecular orbital method2022
- Author(s)
  Tatsunori Miyajima, Midori Takimoto-Kamimura, Norihito Kawashita
- Organizer
  CBI学会2022大会
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] 計算科学によるSMAD4バリアントに対する相互作用エネルギーの解析2022
- Author(s)
  原田一真、板垣あい、川下理日人
- Organizer
  第 50 回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法を用いたIL-6と抗体間の相互作用2022
- Author(s)
  伊丹すず、川下理日人
- Organizer
  第 50 回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] Comparison of conformer models in PDB structure using Fragment Molecular Orbital Method2022
- Author(s)
  Yuuki Okayama, Norihito Kawashita
- Organizer
  CBI学会2022大会
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] 機械学習を用いたp38MAPキナーゼの阻害活性予測2022
- Author(s)
  瀬川颯、川下理日人
- Organizer
  第 50 回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法を用いたBACE1と阻害剤の相互作用解析2022
- Author(s)
  岡山友樹、川下理日人
- Organizer
  第 50 回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法を用いた安定化剤導入時の14-3-3とパートナータンパク質の相互作用解析2022
- Author(s)
  宮嶋起徳、上村みどり、川下理日人
- Organizer
  第 50 回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] In silico analysis of MSH6 proteins by homology modelling; Mechanistic Elucidation of Pathogenicity Variants and Pathogenicity Prediction Virulence of VUS2022
- Author(s)
  Riyo Yoshii, Shino Hashimoto, Kazuo Tamura, Norihito Kawashita
- Organizer
  The 5th International Cancer Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07763
[Presentation] Evaluation of pathogenic variants on MSH2 genes using homology modelling2022
- Author(s)
  Shino Hashimoto, Riyo Yoshii, Kazuo Tamura, Norihito Kawashita
- Organizer
  The 5th International Cancer Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07763
[Presentation] Interaction Analysis between HIV gp120 and the Antibodies by Fragment Molecular Orbital Method2021
- Author(s)
  Yuki Okayama, Atsushi Matsuura, Norihito Kawashita
- Organizer
  Pacifichem2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] ホモロジーモデリングによるMSH2に関する病的バリアントのin silico解析2021
- Author(s)
  橋本志野、好井理世、田村和朗、川下理日人
- Organizer
  日本人類遺伝学会第66回大会
- Data Source
  KAKENHI-PROJECT-19K07763
[Presentation] Interaction analysis of Ebola Virus VP35 with inhibitors using Fragment Molecular Orbital Method2021
- Author(s)
  Kazuma Harada, Norihito Kawashita
- Organizer
  Pacifichem2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法を用いた SARS-CoV-2と抗体の相互作用解析2021
- Author(s)
  相坂奈々美、川下理日人
- Organizer
  第49回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] ホモロジーモデリングを使用したMSH6遺伝子バリアントにおける構造解析2021
- Author(s)
  好井理世、橋本志野、田村和朗、川下理日人
- Organizer
  第27回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07763
[Presentation] Interaction analysis of AKR1C3-inhibitor complexes using fragment molecular orbital method and molecular dynamics simulation2021
- Author(s)
  Hikari Yoshimoto, Norihito Kawashita
- Organizer
  CBI学会 2021大会
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] Interation Analysis between Hel and HyHel10 by fragment molecular orbital method2021
- Author(s)
  Tatsunori Miyajima, Norihito Kawashita
- Organizer
  Pacifichem2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] Interaction analysis of AKR1B10-inhibitor complexes using fragment molecular orbital method2021
- Author(s)
  Hikari Yoshimoto, Norihito Kawashita
- Organizer
  Pacifichem2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] 分子モデリングを用いたMSH2遺伝子の病的バリアントについてのin silico解析2021
- Author(s)
  橋本志野、好井理世、田村和朗、川下理日人
- Organizer
  第27回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07763
[Presentation] Correlation analysis of FimH complex calculation by FMO calculation and experimental results2021
- Author(s)
  Norihito Kawashita, Yu-Shi Tian, Tatsuya Takagi
- Organizer
  Pacifichem2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] ホモロジーモデリングによるMSH6蛋白質domain 1のin silico 解析～病原性バリアントのメカニズム解明と、VUSの病原性予測～2021
- Author(s)
  好井理世、橋本志野、田村和朗、川下理日人
- Organizer
  日本人類遺伝学会第66回大会
- Data Source
  KAKENHI-PROJECT-19K07763
[Presentation] フラグメント分子軌道法を用いた Menin-阻害剤の相互作用解析2021
- Author(s)
  時松和佳菜、川下理日人
- Organizer
  第49回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法を用いた SARS-CoV Mproと阻害剤の相互作用解析2021
- Author(s)
  西條航、川下理日人
- Organizer
  第49回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法および　　分子動力学シミュレーションによる AKR1B10複合体の相互作用解析2021
- Author(s)
  吉本耀、川下理日人
- Organizer
  第49回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法によるXIAPと阻害剤の相互作用解析2020
- Author(s)
  室谷百香、川下理日人
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] PLS回帰を用いたHIV-1 gp120と抗体17bの相互作用解析2020
- Author(s)
  岡山友樹、川下理日人
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] MDM2と阻害剤のフラグメント分子軌道法を用いた相互作用解析2020
- Author(s)
  板東竜也、川下理日人
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法によるエボラウイルスVP35と阻害剤との相互作用解析2020
- Author(s)
  原田一真、川下理日人
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法を用いたHEL/HyHEL-10相互作用解析2020
- Author(s)
  宮嶋起徳、川下理日人
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] APCおよびSMAD9にVUSを検出した大腸ポリポーシス例の遺伝カウンセリング2020
- Author(s)
  小田いつき、西郷和真、池川敦子、木戸慈子、江口英孝、岡﨑康司、石田秀行、冨田尚裕、川下理日人、巽純子、田村和朗
- Organizer
  第44回日本遺伝カウンセリング学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07763
[Presentation] フラグメント分子軌道法によるAKR1B10複合体の相互作用解析2020
- Author(s)
  吉本耀、川下理日人
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] MO計算を用いたSARS-CoV-2のRBD-中和抗体間の相互作用解析2020
- Author(s)
  渡邉一樹、川嶋裕介、福澤薫、渡邉千鶴、本間光貴、田雨時、川下理日人、高木達也
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] 14-3-3と阻害剤の相互作用解析2020
- Author(s)
  富士寛文、川下理日人
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] PREDICTION OF FREE ENERGY BY DOCKING SIMULATION USING INTER-FRAGMENT INTERACTION ENERGIES.2019
- Author(s)
  Hirofumi Fuji, Norihito Kawashita
- Organizer
  BPS2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] Interaction analysis of HIV protease-inhibitor complex by fragment molecular orbital method2019
- Author(s)
  富士寛文、川下理日人
- Organizer
  CBI学会2019年大会
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法を用いた HIVプロテアーゼ阻害剤複合体における結合自由エネルギーの予測2019
- Author(s)
  富士寛文、川下理日人
- Organizer
  第47回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント分子軌道法によるHIVと抗体との相互作用解析2018
- Author(s)
  松浦敦、川下理日人
- Organizer
  第46回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] フラグメント間相互作用エネルギーによる自由エネルギー変化予測の検証2018
- Author(s)
  富士寛文、川下理日人
- Organizer
  第46回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] Interaction Analysis between MDM2 and Its Inhibitors by Fragment Molecular Orbital Method2018
- Author(s)
  Norihito Kawashita, Naoto Motoyama, Tian Yu-Shi, Hirotomo Moriwaki, Tatsuya Takagi
- Organizer
  5th International Symposium of Medicinal Sciences, 139th Annual Meeting of the Pharmaceutical Society of Japan
- Data Source
  KAKENHI-PROJECT-18K06615
[Presentation] Prediction of Serious Adverse Events Using Machine Learning2018
- Author(s)
  Yushi-Tian, Hirotomo Moriwaki, Hiroaki Moriuchi, Satoshi Aoki, Nobuki Takayama, Norihito Kawashita, Takayuki Hibi, Tatsuya Takagi
- Organizer
  19th International Conference on Medicinal Chemistry and Multi Targeted Drug Delivery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0017
[Presentation] Predicting Hydrolyzability using Logistic Regression Analyses and Regularization Techniques2016
- Author(s)
  Tomoko Hatta, Norihito Kawashita, Yu-shi Tian, Tatsuya Takagi
- Organizer
  XVI Chemometrics in Analytical Chemistry 2016
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2016-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460035
[Presentation] Deverlopment of in silico drug resistance evaluation to anti-HIV drugs based on the target protein structures.2015
- Author(s)
  Norihito Kawashita, Tomohiro Ueda, Yu-Shi Tian, Kousuke Okamoto, Tatsuya Takagi
- Organizer
  28th International Conference on Antiviral Research
- Place of Presentation
  Rome, Italy
- Year and Date
  2015-05-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790043
[Presentation] A Novel Combinatorial Regression Mmethod For Avoiding Chance Correlations.2015
- Author(s)
  Tatsuya Takagi, Norihito Kawashita, Tomoko Hatta, Tamaki Takaya, Yushi Tian, Kousuke Okamoto
- Organizer
  XV Chemometrics in Analytical Chemistry 2015
- Place of Presentation
  Changsha，China
- Year and Date
  2015-06-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460035
[Presentation] Chance Correlation を可能な限り回避する回帰手法の開発と応用2015
- Author(s)
  八田朋子, 川下理日人, 田雨時, 高木達也
- Organizer
  第38回ケモインフォマティクス討論会
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460035
[Presentation] mRNA structure prediction targeting antisense oligonucleotides (AONs).2015
- Author(s)
  Yamashita M., Kawashita N., Yamamoto T., Okamoto K., Takagi T., Obika S.
- Organizer
  PACIFICHEM 2015
- Place of Presentation
  米国・ハワイ・ホノルル
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-24249007
[Presentation] Prediction of antisense efficacy using sequence motifs and neural network2014
- Author(s)
  Mako Kitani, Norihito Kawashita, Tsuyoshi Yamamoto, Maki Yamashita, Kousuke Okamoto, Tatsuya Takagi, Satoshi Obika
- Organizer
  International Chemometrics Research Meeting 2014
- Place of Presentation
  Berg en Dal, the Netherlands
- Year and Date
  2014-09-15
- Data Source
  KAKENHI-PROJECT-24249007
[Presentation] FDAデータベースを用いたデータマイニング2010
- Author(s)
  井上藍, 白國優子, 川下理日人, 岡本晃典, 高木達也
- Organizer
  第33回情報化学討論会(徳島)
- Place of Presentation
  徳島大学工学部共通講義棟
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21590157
[Presentation] FDA データベースを用いたデータマイニング2010
- Author(s)
  井上藍、白國優子、川下理日人、岡本晃典、高木達也
- Organizer
  第33回情報化学討論会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590157
[Presentation] 新規ノンパラメトリック回帰手法の応用2009
- Author(s)
  米倉聡, 岡本晃典, 川下理日人, 日高伸之介, 山崎広之, 川瀬雅也, 高木達也
- Organizer
  第32回情報化学討論会山口
- Place of Presentation
  常盤工業会会館(山口)
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-21590157
[Presentation] 新規ノンパラメトリック回帰手法の応用2009
- Author(s)
  米倉聡、岡本晃典、川下理日人、日高伸之介、山崎広之、川瀬雅也、高木達也
- Organizer
  第32回情報化学討論会
- Place of Presentation
  宇部
- Data Source
  KAKENHI-PROJECT-21590157
[Presentation] Statistical Study on Chemical Risk Factors for SJS/TEN2009
- Author(s)
  Y. Shirakuni, E. Uejima, J. Takahara, K. Okamoto, N. Kawashita, T. Yasunaga, S. Inui, T. Takagi
- Organizer
  9th ISoP Annual Meeting
- Place of Presentation
  Reims, France
- Data Source
  KAKENHI-PROJECT-21590157
[Presentation] ドッキングスタディとボルツマン分布を組み合わせた薬剤耐性変異評価法の開発
- Author(s)
  上田智弘, 川下理日人, 岡本晃典, 高木達也
- Organizer
  第37回情報化学討論会
- Place of Presentation
  豊橋商工会議所
- Year and Date
  2014-11-27 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-24790043
[Presentation] A Novel Combinatorial Regression Method for Avoiding Chance Correlations
- Author(s)
  Tatsuya Takagi, Norihito Kawashita, Tomoko Hatta, Tamaki Takaya, Tian Yu-shi, Kousuke Okamoto
- Organizer
  XV Chemometrics in Analytical Chemistry
- Place of Presentation
  長沙、中国
- Year and Date
  2015-06-22 – 2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-25460035
[Presentation] Development of in Silico Drug Resistance Evaluation Systems for Anti-HIV Drugs Based on the Target Protein Structures
- Author(s)
  Norihito Kawashita, Tomohiro Ueda, Yu-Shi Tian, Kousuke Okamoto, Tatsuya Takagi
- Organizer
  28th International Conference on Antiviral Research
- Place of Presentation
  the Parco dei Principi Hotel
- Year and Date
  2015-05-11 – 2015-05-15
- Data Source
  KAKENHI-PROJECT-24790043
[Presentation] 配列モチーフを用いたアンチセンス効果予測モデルの構築
- Author(s)
  木谷真子、川下理日人、山本剛史、山下真季、岡本晃典、高木達也、小比賀聡
- Organizer
  第16回日本RNA学会
- Place of Presentation
  名古屋
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-24249007
[Presentation] Development of Combinatorial Regression Method for Avoiding Chance Correlations
- Author(s)
  Tomoko Hatta, Tamaki Takaya, Tatsuya Takagi, Norihito Kawashita, Kousuke Okamoto
- Organizer
  8th International Conference on Partial Least Squares and Related Methods
- Place of Presentation
  Paris
- Year and Date
  2014-05-26 – 2014-05-28
- Data Source
  KAKENHI-PROJECT-25460035

1. TAKAGI Tatsuya (80144517)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. OKAMOTO Kousuke (70437309)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. UEJIMA Etsuko (80432441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. Satoshi Obika (80243252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. KODAMA Tetsuya (00432443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIHIRO Kunihiko (70713890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Tamura Kazuo (20278823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. 日比孝之 (80181113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 田雨時 (60761252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 冨田尚裕 (00252643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 富田尚裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 田中成典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWASHITA Norihito 川下 理日人

川下 理日人 カワシタ ノリヒト

Research Projects

Research Products

Co-Researchers

Progressive research on genetic testing for hereditary gastrointestinal tumors and fundamental research on next-generation medical genetics

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Development of novel free energy change prediction method independent of entropy changePrincipal Investigator

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Modeling for Prediction of Serious Adverse Events Probabilities of Drug Candidates

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An approach for eliminating chance correlations and its application to pharmaceutical data.

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Deverlopment of in silico drug resistance evaluation based on the target protein structuresPrincipal Investigator

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Development of platform technologies for antisense oligonucleotide-based therapeutics by a combination of nucleic acids chemistry and information sciences

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Study on Adverse Events ofDrugs usingData Mining

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量子化学・分子力学的手法を利用した抗ウイルス剤開発指向ドッキングスタディPrincipal Investigator

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[Journal Article] Protein-ligand binding affinity prediction of cyclin‐dependent kinase‐2 inhibitors by dynamically averaged fragment molecular orbital‐based interaction energy2022

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[Journal Article] FMODB: The World’s First Database of Quantum Mechanical Calculations for Biomacromolecules Based on the Fragment Molecular Orbital Method2021

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[Journal Article] Intermolecular Interaction Analyses on SARS-CoV-2 Spike Protein Receptor Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor-Blocking Antibody/Peptide Using Fragment Molecular Orbital Calculation2021

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[Journal Article] Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome.2019

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[Journal Article] 認定遺伝カウンセラー&reg;の雇用に対する検査会社の視点2019

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[Journal Article] A practical estimation method for analyzing adverse drug reactions using data mining2013

Author(s)

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KAWASHITA Norihito 川下理日人

川下理日人カワシタノリヒト

[Journal Article] 認定遺伝カウンセラー®の雇用に対する検査会社の視点2019

[Presentation] フラグメント分子軌道法を用いた安定化剤導入時の14-3-3とパートナータンパク質の相互作用解析2022