MAEDA Yukihide 前田幸英

Researcher Number	00423327
Affiliation *help	2015 – 2016 : 岡山大学, 大学病院, 助教 2016 : 岡山大学病院, 耳鼻咽喉・頭頸部外科, 助教 2010 – 2013 : Okayama University, 大学病院, 助教 2012 : 岡山大学, 岡山大学病院, 助教 2010 : 岡山大学, 病院, 助教 … More
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 急性感音難聴 / 音響外傷 / 蝸牛 / 免疫染色 / DNAマイクロアレイ / 質量分析計 / プロテオーム / MAP kinase / デキサメタゾン / RNA-seq … More Except Principal Investigator siRNA / 難聴 / GJB2 / 内耳 / FOXP2 / 薬物治療学 / RNA interference / 遺伝子治療学 / deafness / 鼻腔内投与 / 糖質コルチコイド / gene therapy / 嗅球 / ニューロン再生 / 新生児聴覚スクリーニング検査 / 嗅覚 / 神経幹細胞 / 常染色体優性遺伝 / DYX1C1 / Autosomal dominant / 1000Hz ティンパノメトリー / 薬理作用 / 培養 / 突発性難聴 / １０００Hzティンパノメトリー / 治療 / 言語発達 / 蝸牛 / メゼンカイム / 治療効果 / 乳幼児 / プロラクチン / GDF11 / 新生児聴覚スクリーニング / 薬理機序 / ステロイド / 聴覚 / dominant negative / 先天性難聴 / 遺伝子 / 感音難聴 / hearing impairment / 神経細胞移動経路 / ABR / マイクロアレイ / RNA干渉 / dominant negative効果 / 人工内耳 / 組織培養 / DCDC2 / 1000Hzティンパノメトリー / ROBO1 / RNA / 遺伝子治療 / cochlea / 滲出性中耳炎 / 耳科学 / 内耳性難聴 Less

急性感音難聴の分子病態と治療の動態的解析-次世代シークエンスでの統合遺伝子解析-Principal InvestigatorOngoing
- Principal Investigator
  
  前田幸英
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
神経幹細胞を標的とした逆向性吻側移動経路を介した鼻腔内薬剤投与の有効性の検証Ongoing
- Principal Investigator
  
  西崎和則
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
Usefulness of 1000 Hz tympanometry for diagnosis of middle ear infusion in Japanese infants
- Principal Investigator
  
  Kataoka Yuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
Proteomic analysis of acute sensorineural hearing loss and steroid treatment in mice using mass spectrometry approachPrincipal Investigator
- Principal Investigator
  
  Maeda Yukihide
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
学習障害関連遺伝子をターゲットとした人工内耳予後予測因子に関する研究
- Principal Investigator
  
  福島邦博
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
Therapeutic model for acute sensorineural hearing loss using siRNAPrincipal Investigator
- Principal Investigator
  
  MAEDA Yukihide
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
Gene expression in cochlear organ culture : to find a candidate drugs for hearing loss
- Principal Investigator
  
  FUKUSHIMA Kunihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
内耳への経正円窓的遺伝子導入法の開発Principal Investigator
- Principal Investigator
  
  前田幸英
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
A model of gene therapy for autosomal dominant hearing impairment: the application of RNA interference for the treatment of hearing impairment
- Principal Investigator
  
  FUKUSHIMA Kunihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University

All 2017 2016 2015 2013 2012 2011 2010 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] Advances in Otorhinolaryngology2007
- Author(s)
  Maeda Y et al.
- Publisher
  Karger AG(予定)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] Cochlear Transcriptome Following Acoustic Trauma and Dexamethasone Administration Identified by a Combination of RNA-seq and DNA Microarray2017
- Author(s)
  Maeda Y, Omichi R, Sugaya A, Kariya S, Nishizaki K
- Journal Title
  
  Otol Neurotol.
  
  Volume : 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K11181
[Journal Article] Dexamethasone Regulates Cochlear Expression of Deafness-associated Proteins Myelin Protein Zero and Heat Shock Protein 70, as Revealed by iTRAQ Proteomics.2015
- Author(s)
  Maeda Y, Fukushima K, Kariya S, Orita Y, Nishizaki K.
- Journal Title
  
  Otol Neurotol.
  
  Volume : 36 Pages : 1255-1265
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462640
[Journal Article] Time courses of changes in phospho- and total- MAP Kinases in the cochlea after intense noise exposure2013
- Author(s)
  Yukihide Maeda
- Journal Title
  
  PLoS One
  
  Volume : 8(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591880
[Journal Article] Intratympanic dexamethasone up-regulates Fkbp5 in the cochleae of mice in vivo2012
- Author(s)
  Maeda Y, Fukushima K, Kariya S、Orita Y, Nishizaki K.
- Journal Title
  
  Acta Otolaryngol
  
  Volume : 132 Pages : 4-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591880
[Journal Article] Expression analysis of microRNAs in murine cochlear explants2011
- Author(s)
  Hirai M,Maeda Y, Fukushima K, Sugaya A, Kataoka Y, Nishizaki K.
- Journal Title
  
  NeuroReport
  
  Volume : 22 Issue : 13 Pages : 652-654
- Year and Date
  2011-09-14
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591880
[Journal Article] Microarray analysis of the effect of dexamethasone on murine cochlear explants2010
- Author(s)
  Maeda Y, Fukushima K, Hirai M, Kariya S, Smith RJ, Nishizaki K
- Journal Title
  
  Acta Otolaryngol.
  
  Volume : 130 Pages : 1329-1334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591880
[Journal Article] Microarray analysis of the effect of dexamethasone on murine cochlear explants2010
- Author(s)
  Maeda Y, Fukushima K, Hirai M, Kariya S, Smith RJ, Nishizaki K
- Journal Title
  
  Acta Otolaryngol
  
  Volume : 130 Pages : 1329-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591880
[Journal Article] A commentary on 'TECTA mutations in Japanese with mid-frequency hearing loss affected by Zona Pellucida domain protein secretion2010
- Author(s)
  Maeda Y, Fukushima K
- Journal Title
  
  J Hum Genet
  
  Volume : 57 Pages : 619-20
- Data Source
  KAKENHI-PROJECT-22591880
[Journal Article] Cochlear expression of a dominant-negative GJB2R75W construct delivered through the round window membrane in mice.2007
- Author(s)
  Maeda Y, Fukushima K, Kawasaki A, Nishizaki K, Smith RJ
- Journal Title
  
  Neurosci Res. 58
  
  Pages : 250-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591969
[Journal Article] Cochlear expression of a dominant-negative GJB2R75W construct delivered through the round window membrane in mice.2007
- Author(s)
  Maeda Y, Fukushima K, Kawasaki A, Nishizaki K, Smith RJ.
- Journal Title
  
  Neurosci Res. 58
  
  Pages : 250-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791207
[Journal Article] congenital deafness2006
- Author(s)
  Yukihide Maeda, Kunihiro Fukushima, Kazunori Nishizaki
- Journal Title
  
  JOHNS 22
  
  Pages : 1705-1709
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] Smith RJH I In vitro and in vivo suppression of GJB2 expression by RNA interference.2006
- Author(s)
  Maeda Y, Fukushima K, Nishizaki K
- Journal Title
  
  International Journal of pediatric otorhinolaryngology 70
  
  Pages : 1343-1349
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] ここまでわかった遺伝子異常先天性難聴2006
- Author(s)
  前田幸英, 福島邦博, 西崎和則
- Journal Title
  
  Journal of Otolyngology, Head and Neck Surgery 22巻12号
  
  Pages : 1705-1709
- Data Source
  KAKENHI-PROJECT-18791207
[Journal Article] ここまでわかった遺伝子異常耳科領域先天性難聴2006
- Author(s)
  前田幸英, 福島邦博, 西崎和則
- Journal Title
  
  JOHNS 22
  
  Pages : 1705-1709
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] Cochlear expression of a dominant-negative GJB2R75W construct delivered through the round window membrane in mice2005
- Author(s)
  Y Maeda, K Fukushima, K Nishizaki, RJH Smith.
- Journal Title
  
  Neuroscience Research in printing Human molecular genetics 14
  
  Pages : 1641-1650
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] RT-PCR analysis of Tecta, Coch, Eya4 and Strc in mouse cochlear explants.2005
- Author(s)
  Maeda Y, Fukushima_K, Kakiuchi M, Orita Y, Nishizaki K, Smith RJH
- Journal Title
  
  Neuroreport 16
  
  Pages : 361-365
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] In vitro and in vivo suppression of GJB2 expression by RNA interference.2005
- Author(s)
  Maeda Y, Fukushima K, Nishizaki K, Smith RJH
- Journal Title
  
  Human Molec Genet 14
  
  Pages : 1641-1650
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] In vitro and in vivo suppression of GJB2 expression by RNA interference.2005
- Author(s)
  Maeda Y, Fukushima K, Nishizaki K, Smith RJH I
- Journal Title
  
  Human molecular genetics 14
  
  Pages : 1641-1650
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] Cochlear expression of a dominant-negative GJB2R75W construct delivered through the round window membrane in mice(in printing)
- Author(s)
  Y Maeda, K Fukushima, K Nishizaki, RJH Smith.
- Journal Title
  
  Neuroscience Research
- Data Source
  KAKENHI-PROJECT-17390460
[Journal Article] Cochlear expression of a dominant-negative GJB2R75W construct delivered through the round window membrane in mice
- Author(s)
  Y Maeda, K Fukushima, K Nishizaki, RJH Smith
- Journal Title
  
  Neuroscience Research (in printing)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390460
[Presentation] 急性感音難聴モデルマウスへのステロイド投与後の内耳遺伝子発現-RNA―seqとDNAマイクロアレイを用いた解析―2016
- Author(s)
  前田幸英、大道亮太郎、菅谷明子、片岡祐子、假谷伸、西﨑和則
- Organizer
  第26回日本耳科学会総会学術講演会
- Place of Presentation
  長野市
- Year and Date
  2016-10-05
- Data Source
  KAKENHI-PROJECT-16K11181
[Presentation] 乳幼児鼓膜インピーダンス測定における1000Hz tympanometryの有用性の検討2016
- Author(s)
  片岡祐子、菅谷明子、假谷伸、大道亮太郎、前田幸英、西﨑和則
- Organizer
  第26回日本耳科学会総会・学術講演会
- Place of Presentation
  長野県長野市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26462558
[Presentation] Pharmacological action of steroids on spiral nerve axon of the cochlea: a hypothesis based on basic and clinical evidence.2015
- Author(s)
  Yukihide Maeda, Kazunori Nishizaki
- Organizer
  30th Politzer Society Meeting
- Place of Presentation
  新潟市
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462640
[Presentation] 蝸牛におけるステロイド作用機序―Charcot-Marie-Tooth neuropathy関連蛋白、Myelin protein zeroの制御―2015
- Author(s)
  前田幸英、假谷伸、菅谷明子、片岡祐子、西﨑和則
- Organizer
  日本耳科学会
- Place of Presentation
  長崎市
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-25462640
[Presentation] 騒音負荷後のマウス蝸牛における MAP キナーゼ発現とリン酸化の経時的解析2012
- Author(s)
  前田幸英、福島邦博、假谷伸、西崎和則
- Organizer
  日本耳科学会総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2012-10-06
- Data Source
  KAKENHI-PROJECT-22591880
[Presentation] グルココルチコイドによる蝸牛での遺伝子発現制御2011
- Author(s)
  前田幸英
- Organizer
  日本耳鼻咽喉科学会総会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22591880
[Presentation] ミニパネル・ディスカッション「siRNA を用いた内耳遺伝子治療モデル」2008
- Author(s)
  前田幸英
- Organizer
  第27回聴覚生理研究会
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-19591969
[Presentation] ステロイド鼓室内投与のiTRAQプロテオーム解析
- Author(s)
  前田幸英、福島邦博、假谷伸、西﨑和則
- Organizer
  日本耳鼻咽喉科学会総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-25462640
[Presentation] 騒音負荷後のマウス蝸牛におけるMAP キナーゼ発現とリン酸化の経時的解析
- Author(s)
  前田幸英
- Organizer
  日本耳科学会総会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Data Source
  KAKENHI-PROJECT-22591880

1. FUKUSHIMA Kunihiro (50284112)

# of Collaborated Projects : 5results

# of Collaborated Products : 18results
2. KATAOKA Yuko (10362972)

# of Collaborated Projects : 5results

# of Collaborated Products : 3results
3. KARIYA Shin (10274226)

# of Collaborated Projects : 3results

# of Collaborated Products : 5results
4. 菅谷明子 (20600224)

# of Collaborated Projects : 3results

# of Collaborated Products : 3results
5. NISHIZAKI Kazunori (90180603)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
6. 加藤英政 (50292123)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 高原潤子 (80448224)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 折田頼尚 (90362970)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. HIRAI Misato

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

MAEDA Yukihide 前田 幸英

Research Projects

Research Products

Co-Researchers

急性感音難聴の分子病態と治療の動態的解析-次世代シークエンスでの統合遺伝子解析-Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経幹細胞を標的とした逆向性吻側移動経路を介した鼻腔内薬剤投与の有効性の検証Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Usefulness of 1000 Hz tympanometry for diagnosis of middle ear infusion in Japanese infants

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteomic analysis of acute sensorineural hearing loss and steroid treatment in mice using mass spectrometry approachPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

学習障害関連遺伝子をターゲットとした人工内耳予後予測因子に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic model for acute sensorineural hearing loss using siRNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene expression in cochlear organ culture : to find a candidate drugs for hearing loss

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内耳への経正円窓的遺伝子導入法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A model of gene therapy for autosomal dominant hearing impairment: the application of RNA interference for the treatment of hearing impairment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Advances in Otorhinolaryngology2007

Author(s)

Publisher

Description

Data Source

[Journal Article] Cochlear Transcriptome Following Acoustic Trauma and Dexamethasone Administration Identified by a Combination of RNA-seq and DNA Microarray2017

Author(s)

Journal Title

Data Source

[Journal Article] Dexamethasone Regulates Cochlear Expression of Deafness-associated Proteins Myelin Protein Zero and Heat Shock Protein 70, as Revealed by iTRAQ Proteomics.2015

Author(s)

Journal Title

Data Source

[Journal Article] Time courses of changes in phospho- and total- MAP Kinases in the cochlea after intense noise exposure2013

Author(s)

Journal Title

Data Source

[Journal Article] Intratympanic dexamethasone up-regulates Fkbp5 in the cochleae of mice in vivo2012

Author(s)

Journal Title

Data Source

[Journal Article] Expression analysis of microRNAs in murine cochlear explants2011

MAEDA Yukihide 前田幸英

[Journal Article] ここまでわかった遺伝子異常先天性難聴2006

[Journal Article] ここまでわかった遺伝子異常耳科領域先天性難聴2006