Shibata Wataru 芝田渉

… Alternative Names

SHIBATA Wataru 芝田渉

芝田渉シバタワタル

Less

Researcher Number	00435819
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 客員准教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 横浜市立大学, 医学研究科, 客員准教授 2014 – 2017: 横浜市立大学, 先端医科学研究センター, 准教授 2012 – 2013: 横浜市立大学, 医学部, 助教 2010: 朝日生命成人病研究所, 主任研究員 2007: 財団法人朝日生命成人病研究所, その他部局等, 准教授
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Tumor biology
Keywords	Principal Investigator 胃癌 / 不均一性 / 混在癌 / 分化型癌 / 未分化癌 / 線維芽細胞 / NF-ｋB / NFkB / 炎症性腸疾患 / NF-kB … More / 線維化 / 予後予測 / 抗癌剤感受性 / 発癌 / 3次元培養 / Helicobacter / オルガノイド / 幹細胞 … More Except Principal Investigator オルガノイド / 遺伝子発現解析 / 遺伝子変異解析 / 遺伝子発現 / 遺伝子変異 / ３次元オルガノイド培養パネル / 次世代型シークエンサー / 膵臓癌 / EUS-FNA / 網羅的遺伝子解析 / 3次元オルガノイド培養パネル / 胆道癌 / 超音波内視鏡 / 膵癌 / ３次元腫瘍バンク / 阻害剤ライブラリー / 次世代シークエンサー / 胃癌バンク / ３次元初代培養 / 腫瘍バンク / 胃癌 / 肝臓がん / 脂肪肝 / 幹細胞 / 肝癌 / 肝臓癌 / JNK / 動物モデル / 消化管 / 発がん / NF-κB / 炎症 / 癌 / 癌・動物 Less

Mechnism of gastric cancer heterogeneity by comprehensive genetic analysis of clinical specimensPrincipal Investigator
- Principal Investigator
  
  SHIBATA Wataru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yokohama City University
Construction of a 3D tumor bank of pancreaticobiliary cancer for personalized medicine
- Principal Investigator
  
  Sugimori Kazuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Three-dimensional tumor bank for gastric cancer personalized medinine
- Principal Investigator
  
  Tamura Toshihide
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Elucidation of fibrosis mechanism in inflammatory bowel disease and its application to molecular targeting therapyPrincipal Investigator
- Principal Investigator
  
  SHIBATA Wataru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Analysis of signaling pathways for liver cancer stem cell maintenance
- Principal Investigator
  
  MAEDA Shin
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Yokohama City University
Establishment of 3D organotipic culture to identify the gastric stem cells, and to apply for the elucidation of mechanism of gastric cancer and for the novel therapy to gastric cancerPrincipal Investigator
- Principal Investigator
  
  SHIBATA Wataru
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Mechanism of inflammation-associated gastro-intestinal carcinogenesis
- Principal Investigator
  
  MAEDA Shin
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
  The Institute for Adult Diseases, Asahi Life Foundation

All 2020 2019 2017 2016 2015 2014 2013 2009 2008 2007

All Journal Article Presentation

[Journal Article] Quantitative monitoring of circulating tumor DNA in patients with advanced pancreatic cancer undergoing chemotherapy2020
- Author(s)
  Sugimori M、Sugimori K、Tsuchiya H、Suzuki Y、Tsuyuki S, Yoshihiro、Hirotani A、Sanga K、Tozuka Y、Komiyama S、Sato T、Tezuka S、Goda Y、Irie K、Miwa H、Miura Yi、Ishii T、Kaneko T、Nagahama M、Shibata W、Nozaki A、Maeda S
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 1 Pages: 266-278
- DOI
  10.1111/cas.14245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09465
[Journal Article] Helicobacter-induced gastric inflammation alters the properties of gastric tissue stem/progenitor cells2017
- Author(s)
  Wataru Shibata, Soichiro Sue, Sachiko Tsumura, Yasuaki Ishii, Takeshi Sato, Eri Kameta, Makoto Sugimori, HIroaki Yamada, Hiroaki Kaneko, Tomohiko Sasaki, Tomohiro Ishii, Toshihide Tamura, Masaaki Kondo, Shin Maeda
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 17 Issue: 1 Pages: 145-145
- DOI
  10.1186/s12876-017-0706-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09286, KAKENHI-PROJECT-16K19355
[Journal Article] A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.2016
- Author(s)
  Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, Fukushima N, Maeda S, Koike K, Furukawa Y
- Journal Title
  
  Sci Rep
  
  Volume: 印刷中 Issue: 1 Pages: 23899-23899
- DOI
  10.1038/srep23899
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105, KAKENHI-PROJECT-25290045, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-26460425, KAKENHI-PROJECT-26461031, KAKENHI-PROJECT-26462136, KAKENHI-PROJECT-16K15422, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-26860227, KAKENHI-PROJECT-15H04806
[Journal Article] Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.2014
- Author(s)
  Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, Shibata W, Akanuma M, Koike K, Karin M, Maeda S.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 111 Issue: 3 Pages: 1090-1095
- DOI
  10.1073/pnas.1322731111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390092, KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-25290045, KAKENHI-PROJECT-25670186, KAKENHI-PROJECT-25893042
[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth.2009
- Author(s)
  Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata W, Yanai A, Ogura K, Omata M.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 2248-2258
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009
- Author(s)
  Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  J Gastroenterol 44
  
  Pages: 935-943
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009
- Author(s)
  Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 44 Pages: 935-943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth2009
- Author(s)
  Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata Y, Yanai A, Ogura K, Omata M.
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages: 2248-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice.2008
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
- Journal Title
  
  Cancer Res 68
  
  Pages: 5031-5039
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils.2008
- Author(s)
  Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, Ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  Infect Immun 76
  
  Pages: 781-787
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice2008
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
- Journal Title
  
  Cancer Research 68
  
  Pages: 5031-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Activation of Ikappa B kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils2008
- Author(s)
  Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M
- Journal Title
  
  Infect Immun 76
  
  Pages: 781-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Deletion of ASK1 attenuates acetaminophen-induced liver injury by inhibiting JNK activation2008
- Author(s)
  Nakagawa H, Maeda S, Hikiba Y, Ohmae T, Shibata W, Yanai A, Sakamoto K, Ogura K, Noguchi T, Karin M, Ichijo H, Omata M.
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1311-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Cutting edge:The IkappaB kinase(IKK)inhibitor, NEMO-binding domain peptide, bloks inflammatory injury in murine colitis2007
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M
- Journal Title
  
  J Immunol 179
  
  Pages: 2681-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Cutting Edge : The I{kappa}B Kinase (IKK) Inhibitor, NEMO-Binding Domain Peptide, Blocks Inflammatory Injury in Murine Colitis.2007
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M.
- Journal Title
  
  J Immunol 179
  
  Pages: 2681-2685
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Essential roles of high mobility group box 1 in the development of marine colitis and colitis-associated cancer2007
- Author(s)
  Maeda S, Hikiba Y, Shibata W, Ohmae T, Yanai A, Ogura K, Yamada S, Omata M
- Journal Title
  
  Siochem Biophys Res Commun 360
  
  Pages: 394-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] 進行膵癌における化学療法施行中の血中遊離遺伝子中KRAS変異遺伝子モニタリングの有用性の検討．2019
- Author(s)
  杉森慎，杉森一哉，露木翔，廣谷あかね，三箇克幸，佐藤健，手塚瞬，合田賢弘，入江邦泰，三輪治生，芝田渉，野﨑昭人，前田愼
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] 進行膵癌における腫瘍由来血中遊離遺伝子の定量的モニタリングの有用性の検討．2019
- Author(s)
  杉森慎, 杉森一哉, 神保智彩, 中森義典, 露木翔, 金田義弘, 廣谷あかね, 三箇克幸, 戸塚雄一朗, 小宮山哲史, 佐藤健, 手塚瞬, 合田賢弘, 入江邦泰, 三輪治生, 三浦雄輝, 石井寛裕, 芝田渉, 野﨑昭人, 前田愼
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] CLINICAL UTILITY OF THE QUANTITATIVE MONITORING OF CIRCULATING TUMOR DNA IN PATIENTS WITH ADVANCED PDAC UNDERGOING CHEMOTHERAPY.2019
- Author(s)
  Sugimori M, Sugimori K, Jimbo C, Tsuyuki S, Kaneta Y, Hirotani A, Sanga K, Komiyama S, Sato T, Tezuka S, Goda Y, Irie K, Miwa H, Miura Y, Ishii T, Shibata W, Nozaki A, Maeda S
- Organizer
  Digestive Disease Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] Targeted DNA sequencing for advanced gastric carcinoma using next generation sequencing2017
- Author(s)
  芝田渉、津村祥子、須江聡一郎、佐藤健、亀田英里、杉森慎、石井泰明、山田博昭、金子裕明、佐々木智彦、石井寛裕、田村寿英、桐越博之、近藤正晃、前田愼
- Organizer
  第８９回日本胃癌学会
- Place of Presentation
  広島国際会議場、広島県広島市
- Data Source
  KAKENHI-PROJECT-16K09286
[Presentation] Targeting DNA sequencing for advanced gastric carcinoma using next generation sequencing2017
- Author(s)
  Shibata W, Tsumura S, Sue S, Sato T, Kameta E, Sugimori M, Ishii Y, Yamada H, Kaneko H, Sasaki T, Ishii T, Tamura T, Kirikoshi H, Kondo M, Maeda S
- Organizer
  第89回　日本胃癌学会総会総会 oral presentation
- Data Source
  KAKENHI-PROJECT-16K09286
[Presentation] 次世代シークエンサーを用いた胃癌クリニカルシークエンスの試み2017
- Author(s)
  芝田渉、須江聡一郎、佐藤健、亀田英里、杉森慎、石井泰明、山田博昭、金子裕明、佐々木智彦、石井寛裕、田村寿英、近藤正晃、前田愼
- Organizer
  JDDW 2017
- Data Source
  KAKENHI-PROJECT-16K09286
[Presentation] STAT3の活性化がHelicobacter属による胃上皮の増殖と炎症に寄与する2015
- Author(s)
  石井泰明,芝田渉,佐藤健,亀田英里,須江聡一郎,前田愼
- Organizer
  JDDW 2015　第23回日本消化器関連学会週間
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25290045
[Presentation] ヘリコバクター感染による幹細胞マーカー遺伝子発現変化と腫瘍形成能の検討2014
- Author(s)
  芝田渉、須江聡一郎、前田愼
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-24790715
[Presentation] Helicobacter infection promotes mouse gastric organoid growth, and altered the property of gastric stem/progenitor cells2013
- Author(s)
  芝田渉、前田愼
- Organizer
  Digestive disease week
- Place of Presentation
  米国
- Year and Date
  2013-05-19
- Data Source
  KAKENHI-PROJECT-24790715
[Presentation] Helicobacter infection promotes mouse gastric organoid growth, and altered the property of gastric stem/progenitor cells2013
- Author(s)
  芝田　渉、前田愼
- Organizer
  Digestive Disease Week 2013
- Place of Presentation
  オーランドコンベンションセンター（米国）
- Data Source
  KAKENHI-PROJECT-24790715
[Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice2008
- Author(s)
  Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamoto 1 K, Nakagawa H, Ogura K, Karin M, Omata M.
- Organizer
  Digestive Disease Week
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice.2008
- Author(s)
  Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamotol K, Nakagawa H, Ogura K, Karin M, Omata M.
- Organizer
  Digestive Disease Week
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] 消化管癌発生2007
- Author(s)
  前田愼、芝田渉、小俣政男
- Organizer
  増殖におけるC-Jun N-terminal kinaseの役割 Japan Digestive Disease Week (JDDW)
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390205

1. MAEDA Shin (40415956)

# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
2. OGURA Keiji (50376456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
3. YANAI Ayako (10415961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
4. OTSUKA Motoyuki (90518945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Tamura Toshihide (70760065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. Sugimori Kazuya (20448666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 金子裕明 (20760078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMAGUCHI Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 西川祐司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibata Wataru 芝田 渉

SHIBATA Wataru 芝田 渉

芝田 渉 シバタ ワタル

Research Projects

Research Products

Co-Researchers

Mechnism of gastric cancer heterogeneity by comprehensive genetic analysis of clinical specimensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of a 3D tumor bank of pancreaticobiliary cancer for personalized medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Three-dimensional tumor bank for gastric cancer personalized medinine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of fibrosis mechanism in inflammatory bowel disease and its application to molecular targeting therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of signaling pathways for liver cancer stem cell maintenance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of 3D organotipic culture to identify the gastric stem cells, and to apply for the elucidation of mechanism of gastric cancer and for the novel therapy to gastric cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of inflammation-associated gastro-intestinal carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Quantitative monitoring of circulating tumor DNA in patients with advanced pancreatic cancer undergoing chemotherapy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Helicobacter-induced gastric inflammation alters the properties of gastric tissue stem/progenitor cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009

Author(s)

Journal Title

Data Source

Shibata Wataru 芝田渉

SHIBATA Wataru 芝田渉

芝田渉シバタワタル