TATARA Yota 多田羅洋太

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Tatara Yota 多田羅洋太

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Researcher Number	00443995
Other IDs
Affiliation (Current)	2025: 弘前大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2018 – 2025: 弘前大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Basic Section 52040:Radiological sciences-related / Basic Section 52020:Neurology-related
Keywords	Principal Investigator インスリン抵抗性 / 2型糖尿病 / 超硫黄 / インスリン / 骨粗鬆症 / 質量分析 / カテプシンK / コラーゲン / コラーゲン線維 / 骨分解 / グリコサミノグリカン … More Except Principal Investigator … More バイオマーカー / トランスクリプトミクス / メタボロミクス / プロテオミクス / 個人差感受性 / 骨代謝 / マルチオミックス / メッセンジャーRNA / トランスクリプトーム / 骨芽細胞 / 放射線感受性 / 遺伝子発現解析 / メタボロミクス解析 / アルファ線 / 脂質代謝物 / リン脂質 / 代謝物 / 放射線治療 / 癌骨転移 / メタボローム / シナプトタグミン13 / シナプス / 多系統萎縮症 / パーキンソン病 / αシヌクレイン / 低線量放射線 / 酸化修飾応答 / 血清アルブミン / 生物学的線量評価 / 電離放射線 Less

2型糖尿病における超硫黄化インスリンの解析Principal Investigator
- Principal Investigator
  
  多田羅洋太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Hirosaki University
新規伝播調節タンパク質SYT13の制御による異常αシヌクレインの伝播抑制
- Principal Investigator
  
  三木康生
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
Radiation-induced oxidative modification response of serum albumin and its application to dose/damage prediction
- Principal Investigator
  
  Kashiwakura Ikuo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hirosaki University
Elucidating the mechanism of radiosensitivity of cancer bone metastasis regulated by bone metabolism
- Principal Investigator
  
  門前暁
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hirosaki University
A novel function of glycosaminoglycans in degradation of collagen fibrils of bonePrincipal Investigator
- Principal Investigator
  
  Tatara Yota
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Hirosaki University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] がん骨転移を治療するためのバイオマーカーを利用した新たな放射線療法2024
- Author(s)
  門前暁, 多田羅洋太, 小原秀樹, 青木昌彦, Wojcik Andrzej, 真里谷靖
- Journal Title
  
  Precision Medicine
  
  Volume: 7 Pages: 62-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21419
[Journal Article] Proteomics and secreted lipidomics of mouse-derived bone marrow cells exposed to a lethal level of ionizing radiation2023
- Author(s)
  Tatara Yota、Monzen Satoru
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 8802-8802
- DOI
  10.1038/s41598-023-35924-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0181, KAKENHI-PROJECT-23K21419
[Journal Article] Detection of biological responses to low-dose radiation in humans2022
- Author(s)
  Yamaguchi Masaru、Tatara Yota、Nugraha Eka Djatnika、Ramadhani Dwi、Tamakuma Yuki、Sato Yoshiaki、Miura Tomisato、Hosoda Masahiro、Yoshinaga Shinji、Syaifudin Mukh、Kashiwakura Ikuo、Tokonami Shinji
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 184 Pages: 196-207
- DOI
  10.1016/j.freeradbiomed.2022.04.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17887, KAKENHI-PROJECT-20H00556, KAKENHI-PROJECT-21H02860
[Journal Article] Serum Proteomic and Oxidative Modification Profiling in Mice Exposed to Total Body X-Irradiation2022
- Author(s)
  Yamaguchi Masaru、Tatara Yota、Nugraha Eka Djatnika、Sato Yoshiaki、Miura Tomisato、Hosoda Masahiro、Syaifudin Mukh、Tokonami Shinji、Kashiwakura Ikuo
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 9 Pages: 1710-1710
- DOI
  10.3390/antiox11091710
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17887, KAKENHI-PROJECT-20H00556, KAKENHI-PROJECT-21H02860
[Journal Article] Oxidative Modification Status of Human Serum Albumin Caused by Chronic Low-Dose Radiation Exposure in Mamuju, Sulawesi, Indonesia2022
- Author(s)
  Yamaguchi Masaru、Tatara Yota、Nugraha Eka Djatnika、Tamakuma Yuki、Sato Yoshiaki、Miura Tomisato、Hosoda Masahiro、Yoshinaga Shinji、Syaifudin Mukh、Tokonami Shinji、Kashiwakura Ikuo
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 12 Pages: 2384-2384
- DOI
  10.3390/antiox11122384
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17887, KAKENHI-PROJECT-20H00556, KAKENHI-PROJECT-21H02860
[Journal Article] Proteomic changes by radio-mitigative thrombopoietin receptor agonist romiplostim in the blood of mice exposed to lethal total-body irradiation2020
- Author(s)
  Nishida T, Yamaguchi M, Tatara Y, Kashiwakura I
- Journal Title
  
  International journal of radiation biology
  
  Volume: 96 Issue: 9 Pages: 1125-1134
- DOI
  10.1080/09553002.2020.1787546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06106, KAKENHI-PROJECT-18K18190
[Journal Article] Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology2020
- Author(s)
  Kasai, S., Shimizu, S., Tatara, Y., Mimura, J., Itoh, K.
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 2 Pages: 320-320
- DOI
  10.3390/biom10020320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06106
[Journal Article] Proteomic changes by radio-mitigative thrombopoietin receptor agonist Romiplostim in the blood of mice exposed to lethal total-body irradiation2020
- Author(s)
  Nishida T., Yamaguchi M., Tatara Y., Kashiwakura I.
- Journal Title
  
  International Journal of Radiation Biology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06106
[Journal Article] HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum.2020
- Author(s)
  Monzen S, Tatara Y, Mariya Y, Chiba M, Wojcik A, Lundholm L
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 13(6) Issue: 6 Pages: 70-70
- DOI
  10.3892/mco.2020.2140
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22731, KAKENHI-PROJECT-17KK0181, KAKENHI-PROJECT-17H04761, KAKENHI-PROJECT-18K06106
[Journal Article] Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice2020
- Author(s)
  Yokono Y, Hanada K, Narita M, Tatara Y, Kawamura Y, Miura N, Kitayama K, Nakata M, Nozaka M, Kato T, Kudo N, Tsushima M, Toyama Y, Itoh K, Tomita H.
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 9 Issue: 12
- DOI
  10.1161/jaha.119.015616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08530, KAKENHI-PROJECT-18K06106
[Journal Article] Blockade of protease-activated receptor-1 signaling attenuates cardiac hypertrophy and fibrosis in renin-overexpressing hypertensive mice2020
- Author(s)
  Yokono Y., Hanada K., Narita M., Tatara Y., Kawamura Y., Miura N., Kitayama K., Nakata M., Nozaka M., Kato T., Kudo N., Tsushima M., Toyama Y., Itoh, K., Tomita H.
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06106
[Patent] 有害事象の発生又は有害事象の重症度を予測する方法2023
- Inventor(s)
  門前暁, 小原秀樹, 多田羅洋太
- Industrial Property Rights Holder
  国立大学法人弘前大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-172912
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K21419
[Patent] 有害事象の発生又は有害事象の重症度を予測する方法2022
- Inventor(s)
  門前暁、多田羅洋太、小原秀樹
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-162307
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-23K21419
[Patent] 放射線被ばくを検出するためのバイオマーカー2021
- Inventor(s)
  柏倉幾郎、床次眞司、多田羅洋太、E.D. Nugraha他
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-21H02860
[Patent] 認知機能障害のバイオマーカー及びその検出薬、被験者の認知機能障害を検査する方法、認知機能障害の治療又は改善手段を被験者に提示する方法、並びに認知機能障害の治療又は改善物質のスクリーニング方法2020
- Inventor(s)
  多田羅洋太，他6名
- Industrial Property Rights Holder
  弘前大学，他2機関
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-18K06106
[Patent] 認知機能障害のバイオマーカー及びその検出薬、被験者の認知機能障害を検査する方法、認知機能障害の治療又は改善手段を被験者に提示する方法、並びに認知機能障害の治療又は改善物質のスクリーニング方法2019
- Inventor(s)
  多田羅洋太，他6名
- Industrial Property Rights Holder
  弘前大学，他2機関
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-239848
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K06106
[Patent] 動物の軟骨からプロテオグリカンを調製する方法2018
- Inventor(s)
  多田羅洋太，遠藤正彦，須藤晋一郎
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2019
- Data Source
  KAKENHI-PROJECT-18K06106
[Presentation] 放射線治療への抵抗性を示すHER2陽性乳癌における脂質代謝Sphingomyelinの特徴2023
- Author(s)
  門前暁, 菊池愛, 杉山彦斗, 多田羅洋太, 山中天聖, 千葉満, 真里谷靖.
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21419
[Presentation] 前立腺がん骨転移巣の微小環境下で産生されるホスファチジルコリンと細胞特異性2023
- Author(s)
  山中天聖, 門前暁, 菊池愛, 檜山純太, 杉山彦斗, 多田羅洋太, 真里谷靖
- Organizer
  日本放射線技術学会第79回総会学術大会
- Data Source
  KAKENHI-PROJECT-23K21419
[Presentation] Exploring predictors of adverse events Using Urinary Metabolites in volumetric-modulated arc therapy for prostate cancer2022
- Author(s)
  小原秀樹、門前暁、多田羅洋太　他.
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21419
[Presentation] Phosphatidylcholine, a predictive biomarker of therapeutic effect for bone metastasis from CRPC2022
- Author(s)
  Megumi Kikuchi, Karin Oniwa, Junta Hiyama, Hikoto Sugiyama, Yota Tatara, Yasushi Mariya, Satoru Monzen
- Organizer
  第78回日本放射線技術学会総会学術大会
- Data Source
  KAKENHI-PROJECT-23K21419
[Presentation] Metabolomics using urine samples in volumetric modulated arc therapy for prostate cancer2022
- Author(s)
  小原秀樹、門前暁、多田羅洋太　他.
- Organizer
  日本放射線腫瘍学会第35回学術大会
- Data Source
  KAKENHI-PROJECT-23K21419
[Presentation] Investigation of sphingomyelin metabolites under the HER2 positive breast cancer therapy2022
- Author(s)
  門前暁, 堀越舞, 菊池愛, 多田羅洋太, 真里谷靖
- Organizer
  日本放射線腫瘍学会第35回学術大会
- Data Source
  KAKENHI-PROJECT-23K21419
[Presentation] ヒト血清タンパク質の参加修飾に着目した慢性低線量放射線被ばく線量の検出2022
- Author(s)
  山口平，多田羅洋太，Nugraha Djatnika EKA，Ramaddhani DWI，玉熊佑紀，佐藤嘉晃，三浦富智，細田正洋，吉永信治，Syaifudin MUKH，柏倉幾郎，床次眞司
- Organizer
  日本放射線影響学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02860
[Presentation] Serum proteomic and oxidative modification profiling in total body X-irradiated mice2022
- Author(s)
  Ikuo KASHIWAKURA, Masaru YAMAGUCHI, Tota TATARA, Nugraha Djatnika EKA, Yoshiaki SATO, Tomisato MIURA, Masahiro HOSODA, Syaifudin MUKH, Shinji TOKONAMI
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-21H02860
[Presentation] 定量的プロテオミクス解析による急性期放射線骨髄障害の重症化リスク因子の探索2019
- Author(s)
  多田羅洋太，門前暁，伊東健
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06106
[Presentation] 多層オミックス解析による認知症の早期発見のためのバイオマーカー探索2019
- Author(s)
  多田羅洋太
- Organizer
  一般社団法人日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06106
[Presentation] 認知症の予防と早期発見のためのビッグデータ多層解析2018
- Author(s)
  多田羅洋太、中村智洋山嵜博未、中山貴博、青木裕一、丹治邦和、三枝大輔、千葉満、勝岡史城、元池育子、木下賢吾
- Organizer
  第1回COI学会
- Data Source
  KAKENHI-PROJECT-18K06106

1. Kashiwakura Ikuo (00177370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 山口平 (00782822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 伊藤勝博 (20322951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 辻口貴清 (90737454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 三木康生 (30709142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 若林孝一 (50240768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 下山修司 (60736370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 門前暁 (20514136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. 千葉満 (20583735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 三浦富智 (20261456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 居原秀 (60254447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 富田泰史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 花田賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TATARA Yota 多田羅 洋太

Tatara Yota 多田羅 洋太

Research Projects

Research Products

Co-Researchers

2型糖尿病における超硫黄化インスリンの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規伝播調節タンパク質SYT13の制御による異常αシヌクレインの伝播抑制

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Radiation-induced oxidative modification response of serum albumin and its application to dose/damage prediction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the mechanism of radiosensitivity of cancer bone metastasis regulated by bone metabolism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel function of glycosaminoglycans in degradation of collagen fibrils of bonePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] がん骨転移を治療するためのバイオマーカーを利用した新たな放射線療法2024

Author(s)

Journal Title

Data Source

[Journal Article] Proteomics and secreted lipidomics of mouse-derived bone marrow cells exposed to a lethal level of ionizing radiation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of biological responses to low-dose radiation in humans2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum Proteomic and Oxidative Modification Profiling in Mice Exposed to Total Body X-Irradiation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oxidative Modification Status of Human Serum Albumin Caused by Chronic Low-Dose Radiation Exposure in Mamuju, Sulawesi, Indonesia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proteomic changes by radio-mitigative thrombopoietin receptor agonist romiplostim in the blood of mice exposed to lethal total-body irradiation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proteomic changes by radio-mitigative thrombopoietin receptor agonist Romiplostim in the blood of mice exposed to lethal total-body irradiation2020

Author(s)

Journal Title

Data Source

[Journal Article] HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice2020

Author(s)

TATARA Yota 多田羅洋太

Tatara Yota 多田羅洋太