Yamauchi Yoshio 山内祥生

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YAMAUCHI Yoshio 山内祥生

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Researcher Number	00444878
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2016 – 2018: 東京大学, 大学院農学生命科学研究科(農学部), 特任准教授 2015 – 2017: 名古屋大学, 医学系研究科, 講師 2013 – 2015: 名古屋大学, 医学(系)研究科(研究院), 講師 2012: 名古屋大学, 医学(系)研究科(研究院), 助教 2011: 名古屋大学, 医学系研究科, 助教 2008 – 2010: Nagoya University, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Pathological medical chemistry / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Medium-sized Section 38:Agricultural chemistry and related fields / General medical chemistry / Dermatology Except Principal Investigator General medical chemistry / Pathological medical chemistry
Keywords	Principal Investigator コレステロール / 脂質代謝 / 骨格筋 / 癌 / がん / 筋萎縮 / 代謝 / 膜ドメイン / 細胞内輸送 / スフィンゴ糖脂質 … More / ガングリオシド / メラノーマ / 膜接触部位 / 細胞外小胞 / 筋障害 / メタボライト / 食品成分 / iPS細胞 / サルコペニア / 発現制御 / 脂質 / 脂質輸送 / 細胞内脂質輸送 / スフィンゴ脂質 / mTOR / シグナル伝達 / シグナル / ニーマン・ピックC型病 / 糖脂質 / ニーマン-ピック病 / 脂質ラフト / 神経変性疾患 / 神経変成疾患 / Akt / SREBP / Aktシグナル … More Except Principal Investigator シグナル / 糖脂質 / 糖鎖 / シグレック / 脂質 / ノックアウト / 生体分子 / 癌 / シグナル伝達 / シグナル制御 / 脂質修飾 / ガングリオシド / 脂肪酸 / セラミド / スフィンゴ糖脂質 / アストロサイトーマ / マクロファージ / 単球 / 細胞傷害 / 癌免疫 / チェックポイント / シアル酸 / 自然免疫 Less

新規遺伝子改変マウスを用いた細胞外小胞の生体内イメージングとバイオマーカー探索Principal Investigator
- Principal Investigator
  
  山内祥生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  The University of Tokyo
膜接触部位を介した脂質代謝制御機構の解明とその分子栄養学的研究への展開Principal Investigator
- Principal Investigator
  
  山内祥生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Identification of food factors that prevent skeletal muscle atrophy using human iPS cellsPrincipal Investigator
- Principal Investigator
  
  Yamauchi Yoshio
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  The University of Tokyo
Elucidation of the regularoty mechanisms of skeletal muscle homeostasis by metabolite-dependent signalingPrincipal Investigator
- Principal Investigator
  
  Yamauchi Yoshio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Regulation of membrane domain functions by lipid transport and lipid metabolism in cancer cellsPrincipal Investigator
- Principal Investigator
  
  Yamauchi Yoshio
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Mechanisms for innate immune check-point generated by siglecs and sialic acid-containing carbohydrates
- Principal Investigator
  
  FURUKAWA Koichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chubu University
Integrative understanding of linkage between molecular structures and functions of glycosphingolipids in signal regulation
- Principal Investigator
  
  FURUKAWA Koichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Chubu University
Elucidation of signals and metabolic bases that regulate functions of plasma membrane microdomainsPrincipal Investigator
- Principal Investigator
  
  Yamauchi Yoshio
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
  Nagoya University
Intracellular transport and function of cancer- and neurodegenerative disease-related glycosphingolipidsPrincipal Investigator
- Principal Investigator
  
  YAMAUCHI Yoshio
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Analysis of lipid metabolic pathway activated by ganglioside in human melanoma cells and its application to melanoma therapyPrincipal Investigator
- Principal Investigator
  
  YAMAUCHI Yoshio
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Nagoya University

[Book] Glycoscience: Biology and Medicine2015
- Author(s)
  Furukawa K, Ohmi Y, Ohkawa Y, Hashimoto N, Yamauchi Y, Tajima O, Furukawa K
- Total Pages
  1569
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-25460385
[Book] Handbook of Glycosyltransferases and Related Genes2014
- Author(s)
  Koichi Furukawa, Keiko Furukawa, Yuhsuke Ohmi, Yuki Ohkawa, Yoshio Yamauchi, Noboru Hashimoto, Orie Tajima
- Total Pages
  1707
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-25460385
[Book] Glycoscience: Biology and Medicine2014
- Author(s)
  Koichi Furukawa, Yuhsuke Ohmi, Yuki Ohkawa, Noboru Hashimoto, Yoshio Yamauchi, Orie Tajima, Keiko Furukawa
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-25460385
[Journal Article] Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice2021
- Author(s)
  Sasaki Takashi、Watanabe Yuichi、Kuboyama Ayane、Oikawa Akira、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100131-100131
- DOI
  10.1074/jbc.ra120.016203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15786, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-19J22409, KAKENHI-PROJECT-17K19219, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-21K19066
[Journal Article] Polymethoxyflavones in orange peel extract prevent skeletal muscle damage induced by eccentric exercise in rats2020
- Author(s)
  Suzuki Toshihide、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 2 Pages: 440-446
- DOI
  10.1093/bbb/zbaa036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-17K19219, KAKENHI-PROJECT-20H00408
[Journal Article] Bridging molecules are secreted from the skeletal muscle and potentially regulate muscle differentiation2020
- Author(s)
  Chikazawa Miho、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 522 Issue: 1 Pages: 113-120
- DOI
  10.1016/j.bbrc.2019.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15785, KAKENHI-PROJECT-15H05781, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-20H00408
[Journal Article] Functional effect of nobiletin as a food-derived allosteric modulator of mouse CRFR2β in skeletal muscle2020
- Author(s)
  Chikazawa Miho、Moriwaki Yoshitaka、Uramoto Mari、Yamauchi Yoshio、Shimizu Makoto、Shimizu Kentaro、Sato Ryuichiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 529 Issue: 2 Pages: 328-334
- DOI
  10.1016/j.bbrc.2020.03.189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-17K19219
[Journal Article] Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP2020
- Author(s)
  Kuan Yen-Chou、Takahashi Yu、Maruyama Takashi、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 12 Pages: 3918-3928
- DOI
  10.1074/jbc.ra119.011849
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05781, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-20H00408
[Journal Article] Sterol Metabolism and Transport in Atherosclerosis and Cancer2018
- Author(s)
  Yamauchi Yoshio、Rogers Maximillian A.
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 9
- DOI
  10.3389/fendo.2018.00509
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08618
[Journal Article] Cellular Cholesterol Homeostasis in Alzheimer's Disease2017
- Author(s)
  Chang TY, Yamauchi Y, Hasan M, Chang CC
- Journal Title
  
  J Lipid Res
  
  Volume: 印刷中 Issue: 12 Pages: 2239-2254
- DOI
  10.1194/jlr.r075630
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-16K08618
[Journal Article] Methods for Monitoring ABCA1-Dependent Sterol Release2017
- Author(s)
  Yamauchi Y, Yokoyama S, Chang TY
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1583 Pages: 257-273
- DOI
  10.1007/978-1-4939-6875-6_19
- ISBN
  9781493968732, 9781493968756
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-15H02903
[Journal Article] Raft-based interactions of gangliosides with a GPI-anchored receptor2016
- Author(s)
  Komura N, Suzuki KG, Ando H, Konishi M, Koikeda M, Imamura A, Chadda R, Fujiwara TK, Tsuboi H, Sheng R, Cho W, Furukawa K, Furukawa K, Yamauchi Y, Ishida H, Kusumi A, Kiso M.
- Journal Title
  
  Nature Chem Biol
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385
[Journal Article] Raft-based interactions of gangliosides with a GPI-anchored receptor2016
- Author(s)
  N. Komura, K. G. N. Suzuki, H. Ando, M. Konishi, M. Koikeda, A. Imamura, R. Chadda, T. K. Fujiwara, H. Tsuboi, R. Sheng, W. Cho, K. Furukawa, K. Furukawa, Y. Yamauchi, H. Ishida, A. Kusumi (Co-Corresponding Author), and M. Kiso
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: in press Issue: 6 Pages: 402-410
- DOI
  10.1038/nchembio.2059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-13F03404, KAKENHI-PROJECT-26670138, KAKENHI-PROJECT-26291031, KAKENHI-PUBLICLY-15H01212, KAKENHI-PUBLICLY-16H01358, KAKENHI-PROJECT-16H06386, KAKENHI-PROJECT-15H04351, KAKENHI-PROJECT-15H04495, KAKENHI-PROJECT-16F16414, KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-15K14477, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-26460404
[Journal Article] Expression of B4GALNT1, an essential glycosyltransferase for the synthesis of complex gangliosides, suppresses BACE1 degradation and modulates APP processing2016
- Author(s)
  Yamaguchi T, Yamauchi Y, Furukawa K, Ohmi Y, Ohkawa Y, Zhang Q, Okajima T, Furukawa K
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34505-34505
- DOI
  10.1038/srep34505
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-15K19073, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-15K15080, KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-26291020
[Journal Article] Increased expression levels of ppGalNAc-T13 in lung cancers: Significance in the prognostic diagnosis2016
- Author(s)
  Nogimori K, Hori T, Kawaguchi K, Fukui T, Mii S, Nakada H, Matsumoto Y, Yamauchi Y, Takahashi M, Furukawa K, Tetsuya O, Yokoi K, Hasegawa Y, Furukawa K
- Journal Title
  
  Int J Oncol
  
  Volume: 49 Issue: 4 Pages: 1369-1376
- DOI
  10.3892/ijo.2016.3638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-16K19104
[Journal Article] Expression analysis of 0-series gangliosides in human cancer cell lines with monoclonal antibodies generated using knockout mice of ganglioside synthase genes2016
- Author(s)
  Bhuiyan RH, Kondo Y, Yamaguchi T, Tokuda N, Ohkawa Y, Hashimoto N, Ohmi Y, Yamauchi Y, Furukawa K, Okajima T, Furukawa K
- Journal Title
  
  Glycobiology
  
  Volume: 26 Issue: 9 Pages: 984-998
- DOI
  10.1093/glycob/cww049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-26460404, KAKENHI-PUBLICLY-16H01335
[Journal Article] ABCA1-dependent sterol release: sterol molecule specificity and potential membrane domain for HDL biogenesis2016
- Author(s)
  Yamauchi Y, Yokoyama S, Chang TY.
- Journal Title
  
  J Lipid Res
  
  Volume: 57 Issue: 1 Pages: 77-88
- DOI
  10.1194/jlr.m063784
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-15H02903
[Journal Article] Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum2015
- Author(s)
  Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 39 Pages: 23464-23477
- DOI
  10.1074/jbc.m115.662668
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-25461375, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-15H02500, KAKENHI-PROJECT-15H02903, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-15H04696
[Journal Article] Fine tuning of cell signals by glycosylation2012
- Author(s)
  Furukawa K, Ohkawa Y, Yamauchi Y, Hamamura K, Ohmi Y, Furukawa K.
- Journal Title
  
  J Biochem.
  
  Volume: 151 Issue: 6 Pages: 573-578
- DOI
  10.1093/jb/mvs043
- NAID
  10031166098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361, KAKENHI-PUBLICLY-24111519
[Journal Article] Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues.2012
- Author(s)
  Yuhsuke Ohmi
- Journal Title
  
  Neurochemical Research
  
  Volume: 37 Issue: 6 Pages: 1185-1191
- DOI
  10.1007/s11064-012-0764-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-22790280, KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361, KAKENHI-PUBLICLY-24111519
[Journal Article] Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling2011
- Author(s)
  Ohkawa, Y., Ohmi, Y, Tajima, O., Yamauchi, Y, Furukawa, K., Furukawa' K
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 411 Issue: 3 Pages: 483-489
- DOI
  10.1016/j.bbrc.2011.06.118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390076, KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371
[Journal Article] Gangliosides are essential in the protection of inflammation and neuro degeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice2011
- Author(s)
  Ohmi, Y., Tajima, O., Ohkawa, Y., Sugiura, Y., Furukawa, K., Furukawa, K.
- Journal Title
  
  J.Neurochem.
  
  Volume: 116 Issue: 5 Pages: 926-935
- DOI
  10.1111/j.1471-4159.2010.07067.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390076, KAKENHI-PROJECT-22790280
[Journal Article] Functional activation of Src family kinase Yes is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD32011
- Author(s)
  Hamamura, K., Tsuji, M., Hotta, H., Ohkawa, Y., Takahashi, M., Shibuya, H., Nakashima, H., Yamauchi, Y., Hashimoto, N., Hattori, H., Ueda, M., Furukawa, K., Furukawa. K
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Issue: 21 Pages: 18526-37
- DOI
  10.1074/jbc.m110.164798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390076, KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361
[Journal Article] Functional activation of Src family kinase yes protein is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD32011
- Author(s)
  Hamamura K, Tsuji M, Hotta H, Ohkawa Y, Takahashi M, Shibuya H, Nakashima H, Yamauchi Y, Hashimoto N, Hattori H, Ueda M, Furukawa K, Furukawa K
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 18526-18537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280
[Journal Article] Gangliosides are essential in the protection of inflammation and neuro degeneration via maintenance of lipid rafts : elucidation by a series of ganglioside-deficient mutant mice.2011
- Author(s)
  Ohmi Y, Tajima O, Ohkawa Y, Yamauchi Y, Sugiura Y, Furukawa K, Furukawa K.
- Journal Title
  
  J Neurochem
  
  Volume: 116 Pages: 926-935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280
[Journal Article] Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling : induction of the lipgenic pathway by a melanoma antigen2011
- Author(s)
  Yamauchi Y, Furukawa K, Hamamura K, Furukawa K.
- Journal Title
  
  Cancer Res.
  
  Volume: 71 Issue: 14 Pages: 4989-4997
- DOI
  10.1158/0008-5472.can-10-4108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23790361
[Journal Article] GM1/GD1b/GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line2010
- Author(s)
  Dong Y, Ikeda K, Hamamura K,Zhang Q, Kondo Y, Matsumoto Y, Ohmi Y, Yamauchi Y, Furukawa K, Taguchi R, Furukawa K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Issue: 9 Pages: 2039-2047
- DOI
  10.1111/j.1349-7006.2010.01613.x
- NAID
  10027831670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280
[Journal Article] Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains.2010
- Author(s)
  Ohkawa Y, Miyazaki S, Hamamura K, Kambe M, Miyata M, Tajima O, Ohmi Y, Yamauchi Y, Furukawa K, Furukawa K.
- Journal Title
  
  J Bid Chem
  
  Volume: 285 Pages: 27213-27223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280
[Journal Article] GM1/GD1b/GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.2010
- Author(s)
  Dong Y, Ikeda K, Hamamura K, Zhang Q, Kondo Y, Matsumoto Y, Ohmi Y, Yamauchi Y, Furukawa K, Taguchi R, Furukawa K.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2039-2047
- NAID
  10027831670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280
[Journal Article] Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains2010
- Author(s)
  Ohkawa Y, Miyazaki S, Hamamura K, Kambe M, Miyata M,Tajima O, Ohmi Y, Yamauchi Y, Furukawa K, Furukawa K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Issue: 35 Pages: 27213-27223
- DOI
  10.1074/jbc.m109.087791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790280
[Journal Article] GM1/GD1b/GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.2010
- Author(s)
  Dong Y., Ikeda K., Hamamura K., Zhang Q., Kondo Y., Matsumoto Y., Ohmi Y., Yamauchi Y., Furukawa K., Taguchi R., Furukawa K.
- Journal Title
  
  (in press)
- NAID
  10027831670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790796
[Journal Article] 脂質ラフトを介するシグナル制御と糖脂質糖鎖機能2008
- Author(s)
  古川鋼一、山内祥生、章青、大海雄介、古川圭子
- Journal Title
  
  日本内分泌学会雑誌 84
  
  Pages: 147-147
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] 27-hydroxycholesterol産生に基づくミトコンドリアへのコレステロール輸送の評価2021
- Author(s)
  小澤光，齋藤穂高，佐藤隆一郎，山内祥生
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] メバロン酸経路はヒトiPS細胞由来骨格筋細胞においてタンパク質恒常性を制御する2021
- Author(s)
  趙尭琳，久保美遥、櫻井英俊、佐藤隆一郎、山内祥生
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] ヒト及びマウス骨格筋由来細胞外小胞のプロテオミクス解析2021
- Author(s)
  渡辺祥、須藤優里、櫻井英俊、佐藤隆一郎、山内祥生
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] 骨格筋特異的な胆汁酸受容体TGR5の過剰発現はグルコースクリアランスを改善する2021
- Author(s)
  佐々木崇、渡邉雄一、久保山文音、及川彰、清水誠、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] 脂質輸送タンパク質を介したコレステロール恒常性制御2021
- Author(s)
  齋藤穂高，山内祥生，佐藤隆一郎
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] ヒトおよびマウス骨格筋細胞が分泌するエクソソームの生化学的解析2020
- Author(s)
  須藤優里、櫻井英俊、佐藤隆一郎、山内祥生
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] ヒトiPS細胞を活用した食品機能性研究の基盤構築2020
- Author(s)
  山内祥生
- Organizer
  日本農芸化学会2020年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] 骨格筋障害・萎縮におけるABCA1遺伝子発現応答の解析2020
- Author(s)
  小野敦子、清水誠、近澤未歩、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] 骨格筋障害・萎縮におけるABCA1遺伝子発現応答の解析2020
- Author(s)
  小野敦子、清水誠、近澤未歩、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] 腸内細菌が産生する脂肪酸代謝産物のヒトiPS小腸モデルを用いた生理機能解明2020
- Author(s)
  野口惇、清水誠、高橋裕、岸野重信、小川順、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] コレステロール恒常性維持機構とその生理的な役割2019
- Author(s)
  山内祥生
- Organizer
  第73回日本栄養・食糧学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] Regulation of cellular sterol homeostasis by endogenous oxysterols2019
- Author(s)
  山内祥生
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] コレステロール恒常性維持機構とその生理的な役割2019
- Author(s)
  山内祥生
- Organizer
  第73回日本栄養・食糧学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] 細胞内で産生された酸化ステロールによるコレステロール代謝制御2019
- Author(s)
  齋藤穂高、佐藤隆一郎、山内祥生
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] Regulation of cellular sterol homeostasis by endogenous oxysterols2019
- Author(s)
  山内祥生
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] Role of endogenous oxysterols in cellular cholesterol homeostasis2019
- Author(s)
  Yoshio Yamauchi, Hodaka Saito, Ryuichiro Sato
- Organizer
  60th International Conference on the Bioscience of Lipids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] 脂質代謝制御因子Insigを介した酸化ステロールによる新規応答2019
- Author(s)
  渡邉雄一、三吉翔子、清水誠、山内祥生、佐藤隆一郎
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] 細胞内で産生された酸化ステロールによるコレステロール代謝制御2019
- Author(s)
  齋藤穂高、佐藤隆一郎、山内祥生
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H02908
[Presentation] 細胞ステロールセンシング：制御機構とその異常2018
- Author(s)
  山内祥生
- Organizer
  第102回日本栄養・食糧学会関東支部シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] 内因性酸化ステロールによるコレステロール恒常性制御2018
- Author(s)
  齋藤穂高、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] 内因性酸化ステロールがSREBP-2活性に及ぼす影響2018
- Author(s)
  齋藤穂高、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] mTORシグナルによるSREBP活性化機序の解析2018
- Author(s)
  山内祥生、古川鋼一、佐藤隆一郎
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] 内因性酸化ステロールによるコレステロール代謝制御機構に及ぼす影響2018
- Author(s)
  齋藤穂高、山内祥生、佐藤隆一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] 骨格筋萎縮時に発現誘導されるAnkrd1の機能解析2018
- Author(s)
  吉田壮志、橋詰力、清水誠、井上順、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] mTORシグナルによるコレステロール代謝調節機構2018
- Author(s)
  山内祥生、佐藤隆一、古川鋼一
- Organizer
  第72回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] SREBP-SCAP相互作用部位の解析2018
- Author(s)
  丸山貴史、官産州、清水誠、山内祥生、佐藤隆一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] Sterol flux at the plasma membrane and sterol sensing at the ER2018
- Author(s)
  山内祥生
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] がん細胞におけるlipogenic phenotypeの重要性とその制御機構2017
- Author(s)
  山内祥生
- Organizer
  第59回日本脂質生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] ABCA1依存的HDL形成におけるステロール分子特異性と膜ドメイン2017
- Author(s)
  山内祥生、横山信治，Ta-Yuan Chang
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学、京都府京都市
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] ABCA1依存的HDL形成におけるステロール分子特異性と膜ドメイン2017
- Author(s)
  山内祥生、横山信治，Ta-Yuan Chang
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学、京都府京都市
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] SREBPプロセシングを阻害する新規低分子量化合物によって明らかになったヒトメラノーマ細胞におけるSREBP依存的なメバロン酸経路の重要性，ポスター2016
- Author(s)
  山内祥生，太田晃成，渡邉瑞貴，五十嵐政智，佐藤隆一郎，上杉志成，古川鋼一
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08618
[Presentation] SREBPプロセシングを阻害する新規低分子量化合物によって明らかになったヒトメラノーマ細胞におけるSREBP依存的なメバロン酸経路の重要性，ポスター2016
- Author(s)
  山内祥生，太田晃成，渡邉瑞貴，五十嵐政智，佐藤隆一郎，上杉志成，古川鋼一
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] Expression and roles of asialo-series gangliosides in human cancer cell lines2015
- Author(s)
  Robiul H. Bhuiyan, Yuji Kondo, Tokiaki Yamaguchi, Noriyo Tokuda, Yuki Ohkawa, Yuhsuke Ohmi, Yoshio Yamauchi, Keiko Furukawa, Tetsuya Okajima, Koichi Furukawa
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] ヒトmelanoma細胞におけるNeogenin細胞内ドメイン（NeICD）標的遺伝子の同定2015
- Author(s)
  金子慶、大川祐樹、橋本登、大海雄介、山内祥生、岡島徹也、小谷典弘、本家孝一、古川圭子、古川鋼一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] ABCトランスポーターABCA1はダイナミン依存症エンドサイトーシスを介したステロール逆行輸送を調整する2015
- Author(s)
  山内祥、岩本紀之、Maximilian A Rogers,どう前純子、藤本豊士、Catherine C.Y.Chang,石神正登、岩本拓磨、小林俊秀、植田和光、古川鋼一、Ta-Yuan Chag,横山信治
- Organizer
  第３８回日本分子生物学会年会、第８８回日本生化学会大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04696
[Presentation] ヒトmelanoma細胞におけるNeogenin細胞内ドメイン（NelCD）標的遺伝子の同定2015
- Author(s)
  金子　慶、大川祐樹、橋本　登、大海雄介、山内祥生、岡島徹也、小谷典弘、本家孝一、古川圭子、古川鋼一
- Organizer
  第７４回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H04696
[Presentation] Neogenin 細胞内領域（NelCD）はGD3発現メラノーマにおいて、癌悪性形質亢進に関与する2015
- Author(s)
  金子慶、大川祐樹,橋本登、大海雄介、山内祥生、岡島徹也、小谷典弘、本屋孝一、古川圭子、古川鋼
- Organizer
  第３４回日本糖質学会年会
- Place of Presentation
  東京大学安田講堂（東京都）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-15H04696
[Presentation] ABCトランスポーターABCA1はダイナミン依存性エンドサイトーシスを介したステロール逆行輸送を調節する2015
- Author(s)
  山内祥生、岩本紀之、Maximillian A. Rogers, 堂前純子、藤本豊士、Catherine Chang、石神正登、岸本拓磨、小林俊秀、植田和光、古川鋼一、Ta-Yuan Chang、横山信治
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場、兵庫県神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] Expression and roles of asialo-series gangliosides in human cancer cell lines2015
- Author(s)
  Robiul H .Bhuiyan,Yuji Kondo,Tokiaki,Yamaguti,Noriyo Tokuda,Yuki ohkawa,Yuhsuke Ohmi,Yoshio Yamauchi,Keiko Furukawa,Tetsuya Okajima,Koichi Furukawa
- Organizer
  第７４回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H04696
[Presentation] Neogenin細胞内領域（NeICD）は GD3発現メラノーマにおいて、癌悪性形質亢進に関与する2015
- Author(s)
  金子慶、大川祐樹、橋本登、大海雄介、山内祥生、岡島徹也、小谷典弘、本家孝一、古川圭子、古川鋼一
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学、東京都文京区
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] SCAPを標的とした新規低分子量化合物から明らかになったがん細胞におけるSREBP依存的メバロン酸経路の重要性2015
- Author(s)
  山内祥生、太田晃成、渡辺瑞貴、五十嵐政智、上杉志成、古川鋼一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] スフィンゴ糖脂質合成の調節におけるp24タンパク質の関与の検討2013
- Author(s)
  山内祥生、山口世堯、藤田盛久、木下タロウ、古川鋼一
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場、神戸市
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] The lipogenic phenotype of human melanoma cells expressing ganglioside GD3 is regulated by mTOR-mediated lipid sensing at the ER2013
- Author(s)
  山内祥生、五十嵐政智、古川鋼一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] mTOR-mediated lipid sensing regulates the lipogenic phenotype in human cancer cells2013
- Author(s)
  Yoshio Yamauchi
- Organizer
  The 5th Nagoya Global Retreat
- Place of Presentation
  大府市
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] mTOR signaling regulates sterol regulatory element binding proteins by mediating lipid sensing2013
- Author(s)
  Yoshio Yamauchi, Masatomo Igarashi, Koichi Furukawa
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] GD3発現メラノーマの悪性形質におけるNeogeninの機能2013
- Author(s)
  金子慶、大川祐樹、橋本登、大海雄介、山内祥生、小谷典弘、本家孝一、古川圭子、古川鋼一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] Roles of Neogenin in GD3-expressing human melanoma cells2013
- Author(s)
  Kei Kaneko, Yuki Ohkawa, Noboru Hashimoto, Yusuke Ohmi, Yoshio Yamauchi, Norihiro Kotani, Koichi Honke, Keiko Furukawa, Koichi Furukawa
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] ガングリオシドGM1によるAPPの切断とその切断断片により誘導される細胞死の制御2013
- Author(s)
  山口世堯、山内祥生、松本康之、大川祐樹、大海雄介、橋本登、近藤裕史、古川圭子、古川鋼一
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター、大阪市
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] ガングリオシドによるamyloid β precursor protein(APP) の切断パターンの制御及びAPP切断断片が細胞の健常性に与える影響2013
- Author(s)
  山口世堯、山内祥生、松本康之、大川祐樹、大海雄介、橋本　登、近藤裕史、古川圭子、古川鋼一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] Role of mTOR kinase in the lipogenic phenotype of human cancer cells2012
- Author(s)
  山内祥生, 五十嵐政智, 古川鋼一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場, 福岡市
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Miglustat and cyclodextrin promote lysosome-to- plasma membrane transport of disease-associated gangliosides in Niemann-Pick type C cells2012
- Author(s)
  Yoshio Yamauchi
- Organizer
  Gordon Research Conference, Glycolipid & Sphingolipid Biology
- Place of Presentation
  Lucca, Italy
- Year and Date
  2012-04-24
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Role of mTOR kinase in the lipogenic phenotype of human cancer cells2012
- Author(s)
  山内祥生
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Regulation of cholesterol homeostasis by ABCA1-dependent retrograde sterol transport2012
- Author(s)
  山内祥生
- Organizer
  第7回トランスポーター研究会年会
- Place of Presentation
  京都大学, 京都市
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Miglustat and cyclodextrin promote lysosome-to-plasma membrane transport of diseased-associated gangliosides in Niemann-Pick type C cells.2012
- Author(s)
  Yoshio Yamauchi
- Organizer
  Gordon Research Conference, Glycolipid & Sphingolipid Biology
- Place of Presentation
  Lucca, Italy
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Regulation of cholestrol homeostasis by ABCA1-dependent retrograde sterol transport2012
- Author(s)
  山内祥生
- Organizer
  第７回トランスポーター研究会年会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] ABCA1, sterol sensing, and membrane mesodomains2011
- Author(s)
  Yamauchi Y.
- Organizer
  ABC2011 in Kyoto -ABC Proteins/Membrane Meso-domains/ES-iPS cells
- Place of Presentation
  京都大学(京都府)(招待講演)
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] The Niemann-Pick type C protein NPC1 regulates trafficking of disease-associated gangkiosides from the lysosome to the plasma membrane2011
- Author(s)
  Yamauchi Y, Yoshida K, Chang T.Y, Furukawa K, Furukawa K.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] ABCA1, membrane meso-domains, and sterol sensing2011
- Author(s)
  Yoshio Yamauchi
- Organizer
  iCeMS Joint International Symposium ABC 2011 in Kyoto
- Place of Presentation
  京都大学, 京都市
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling : Induction of the lipogenic pathway by a melanoma antigen2011
- Author(s)
  Yoshio Yamauchi, Keiko Furukawa, Kazunori Hamamura, Koichi Furukawa
- Organizer
  The 30th Naito Conference on Membrane Dynamics and Lipid Biology [II] : Domains, Droplets and Diseases
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ, 札幌市
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Tumor antigen- activated lipogenic pathway is regulated via mTOR signaling : Crucial role of mTOR-SREBP pathway in the integrity of lipid rafts2011
- Author(s)
  山内祥生, 古川圭子, 浜村和紀, 古川鋼一
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館, 京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Total analyses on the roles of cancer-associated gangliosides in malignant properties of melanomas2011
- Author(s)
  Yamauchi Y, Hamamura K, Ohkawa Y, Hashimoto N, Ohmi Y, Furukawa K, Furukawa K
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Total analyses on the roles of cancer-associated gangliosides in malignant properties of melanomas2011
- Author(s)
  Yoshio Yamauchi, Kazunori Hamamura, Yuki Ohkawa, Noboru Hashimoto, Yuhsuke Ohmi, Keiko Furukawa, Koichi Furukawa
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋国際会議場, 名古屋市
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling : Introduction of the lipogenic pathway by a melanoma antigen2011
- Author(s)
  Yamauchi Y., Furukawa K, Hamamura K., Furukawa K.
- Organizer
  The 30^<th> Naito Conference on Membrane Dynamics and Lipid Biology [II] : Domains, Droplets and Diseases
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ(北海道)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Tumor antigen-activated lipogenic pathway is regulated via mTOR signaling : Crucial role of mTOR-SREBP pathway in the integrity of lipid rafts2011
- Author(s)
  山内祥生、古川圭子、浜村和紀、古川鋼一
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] The Niemann- Pick type C protein NPC1 regulates trafficking of disease-associated ganglioside from the lysosome to the plasma membrane2011
- Author(s)
  Yoshio Yamauchi, Kosuke Yoshida, Ta-Yuan Chang, Keiko Furukawa, Koichi Furukawa
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜, 横浜市
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Tumor antigen-activated lipogenic pathway is regulated via mTOR signaling : Crucial role of mTOR-SREBP pathway in the integrity of lipid rafts2011
- Author(s)
  Yamauchi Y.
- Organizer
  Global COE Program The 3rd International Symposium -New Trends in Basic and Clinical Cancer Research for Innovative Therapy
- Place of Presentation
  ミッドランドホール(愛知県)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Accumulation of disease-related ganglosides in the late endosome/lysosome and small molecules that stimulates their transport to the plasma membrane in Niemann-Pick type C cells2010
- Author(s)
  Yoshio Yamauchi, Kosuke Yoshida, Ta-Yuan Chang, Koichi Furukawa
- Organizer
  GlycoT 2010 Tokyo 7th International Symposium on Glycosyltransferases
- Place of Presentation
  KFC-Kokusai Fashion Center, 東京都墨田区
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Lysosomal accumulation of disease-associated gangliosides and small molecules that stimulate their lysosome-to-plasma membrane transport in Niemamm-Pick type C cells2010
- Author(s)
  Yoshio Yamauchi, Kosuke Yoshida, Ta-Yuan Chang, Keiko Furukawa, Koichi Furukawa
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場, 神戸市
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] Lysosomal accumulation of disease-associated gangliosides and small molecules that stimulate their lysosome-to-plasma membrane transport in Niemann-Pick type C cells.2010
- Author(s)
  Yamauchi Y, Yoshida K, Chang TY, Furukawa K, Furukawa K.
- Organizer
  日本分子生物学会年会・日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22790280
[Presentation] ヒトメラノーマ細胞においてSREBP経路はAktシグナルによって制御されている2009
- Author(s)
  山内祥生、古川圭子、古川鋼一
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] Role of SREBP pathway in Akt signaling in human melanoma cells2009
- Author(s)
  山内祥生、古川圭子、古川鋼一
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] Ganglioside GD3-dependent Akt signaling leads to activation of SREBP to regulate lipogenesis in human melanoma cells2008
- Author(s)
  山内祥生、渡邊夕樹、宮崎清香、古川圭子、古川鋼一
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] 脂質ラフトを介するシグナル制御と糖脂質糖鎖2008
- Author(s)
  古川鋼一、山内祥生、浜村和紀、章青、大海雄介、愛新覚羅維、古川圭子
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] ヒトメラノーマ細胞においてガングリオシドGD3はAktシグナルを介してSREBPを活性化する2008
- Author(s)
  山内祥生、渡邊夕樹、宮崎清香、古川圭子、古川鋼一
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] ヒトメラノーマ細胞においてガングリオシドGD3はAktシグナルを介してSREBPを活性化する2008
- Author(s)
  山内祥生、他4名
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] Ganglioside GD 3 dependent Akt signaling leads to activation of SREBP to regulate lipogenesis in melanoma cells2008
- Author(s)
  山内祥生、他4名
- Organizer
  第81回日本生化学会大会、第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20790796
[Presentation] mTORシグナルは小胞体での脂質センシングを制御し、がん細胞のリポジェニックフェノタイプを増強する
- Author(s)
  山内祥生、五十嵐政智、太田晃成、古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館、京都府京都市
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] GD3発現メラノーマにおけるNeogeninの悪性形質創出メカニズム
- Author(s)
  金子慶、大川祐樹、橋本登、大海雄介、小川光貴、山内祥生、小谷典弘、本家孝一、古川圭子、古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館、京都府京都市
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] SREBPのプロセシングを標的とした新規低分子化合物はメラノーマ細胞の悪性形質を抑制する
- Author(s)
  太田晃成、山内祥生、山口世堯、渡辺瑞貴、古川圭子、上杉志成、古川鋼一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] ガングリオシドによるAPP切断とその切断断片による酸化ストレス応答の制御
- Author(s)
  山口世堯、山内祥生、松本康之、橋本登、大海雄介、近藤裕史、古川圭子、古川鋼一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館、京都府京都市
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] スフィンゴ糖脂質の生合成におけるp24タンパク質の役割
- Author(s)
  山内祥生、Alkmini Papadopoulou、古川鋼一
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学、愛知県名古屋市
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-25460385
[Presentation] Establishment of anti-GD1alpha mAbs and expression analysis of asialo-series gangliosides in human cancer cell lines
- Author(s)
  Robiul H. Bhuiyan, Yuji Kondo, Tokiaki Yamaguchi, Noriyo Tokuda, Yoshio Yamauchi, Keiko Furukawa, Tetsuya Okajima, Koichi Furukawa
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460385

1. FURUKAWA Koichi (80211530)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
2. UESUGI Motonari (10402926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. OHKAWA Yuki (40723896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. ANDO Hiromune (20372518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUZUKI Kenichi (50423059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKEDA Kazutaka (10466732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HONKE Koichi (80190263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 橋本登 (90712365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大海雄介 (10584758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 佐々木栄太 (00803157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. CHANG Ta-Yuan Chang

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. SHIMIZU Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 楠見明弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 近澤未歩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 佐藤隆一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 佐々木崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamauchi Yoshio 山内 祥生

YAMAUCHI Yoshio 山内 祥生

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新規遺伝子改変マウスを用いた細胞外小胞の生体内イメージングとバイオマーカー探索Principal Investigator

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膜接触部位を介した脂質代謝制御機構の解明とその分子栄養学的研究への展開Principal Investigator

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Identification of food factors that prevent skeletal muscle atrophy using human iPS cellsPrincipal Investigator

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Elucidation of the regularoty mechanisms of skeletal muscle homeostasis by metabolite-dependent signalingPrincipal Investigator

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Regulation of membrane domain functions by lipid transport and lipid metabolism in cancer cellsPrincipal Investigator

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Mechanisms for innate immune check-point generated by siglecs and sialic acid-containing carbohydrates

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Integrative understanding of linkage between molecular structures and functions of glycosphingolipids in signal regulation

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Elucidation of signals and metabolic bases that regulate functions of plasma membrane microdomainsPrincipal Investigator

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Intracellular transport and function of cancer- and neurodegenerative disease-related glycosphingolipidsPrincipal Investigator

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Analysis of lipid metabolic pathway activated by ganglioside in human melanoma cells and its application to melanoma therapyPrincipal Investigator

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[Book] Glycoscience: Biology and Medicine2015

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[Book] Handbook of Glycosyltransferases and Related Genes2014

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[Book] Glycoscience: Biology and Medicine2014

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[Journal Article] Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice2021

Yamauchi Yoshio 山内祥生

YAMAUCHI Yoshio 山内祥生