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Uemura Sotaro  上村 想太郎

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UEMURA Sotaro  上村 想太郎

上村 想太郎  ウエムラ ソウタロウ

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Researcher Number 00447442
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院理学系研究科(理学部), 教授
Affiliation (based on the past Project Information) *help 2020 – 2023: 東京大学, 大学院理学系研究科(理学部), 教授
2007 – 2008: The University of Tokyo, 大学院・薬学系研究科, 助教
Review Section/Research Field
Principal Investigator
Biological Sciences / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Except Principal Investigator
Medium-sized Section 27:Chemical engineering and related fields
Keywords
Principal Investigator
リボソーム / タンパク質翻訳 / GFP / 1分子計測 / 蛍光イメージング / ZMW法 / 膜タンパク質 / 1分子 / 脂質膜 / ナノポア … More / 機械学習 / ペプチド / ナノポア計測 / 1分子計測 … More
Except Principal Investigator
微生物 / イメージング / 遺伝学 / 発酵 / 酵母 / 細胞分取 / 指向性進化法 Less
  • Research Projects

    (4 results)
  • Research Products

    (48 results)
  • Co-Researchers

    (4 People)
  •  Comprehensive Single-Molecule Protein Quantification Analysis Using Ribosome-Integrated Nanopore TechnologyPrincipal Investigator

    • Principal Investigator
      UEMURA Sotaro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo
  •  Intelligent directed evolution: technology development and application to yeast

    • Principal Investigator
      Goda Keisuke
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 27:Chemical engineering and related fields
    • Research Institution
      The University of Tokyo
  •  リボソームのタンパク質合成メカニズムの1分子機能解析Principal Investigator

    • Principal Investigator
      上村 想太郎
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  光ピンセット法によるタンパク質翻訳機構の1分子操作Principal Investigator

    • Principal Investigator
      上村 想太郎
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2020 2009 2008 2007

All Journal Article Presentation Book

  • [Book] 最新分子マシン2008

    • Author(s)
      上村 想太郎
    • Total Pages
      145
    • Publisher
      化学同人編集部編
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Book] 最新分子マシン2008

    • Author(s)
      上村 想太郎
    • Total Pages
      145
    • Publisher
      化学同人編集部編
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Journal Article] Comprehensive quantitative analysis of single-molecule proteins using ribosome fusion nanopore technology2023

    • Author(s)
      Uemura Sotaro
    • Journal Title

      Impact

      Volume: 2023 Issue: 2 Pages: 50-52

    • DOI

      10.21820/23987073.2023.2.50

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Journal Article] Accumulation of TERT in mitochondria shows two opposing effects on apoptosis2023

    • Author(s)
      Hiroshi Ebata, Tomohiro Shima, Ryo Iizuka, Sotaro Uemura
    • Journal Title

      FEBS Open Bio

      Volume: 13 Issue: 9 Pages: 1667-1682

    • DOI

      10.1002/2211-5463.13682

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K05310, KAKENHI-PROJECT-21K18232
  • [Journal Article] Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation2023

    • Author(s)
      Tanaka Yumiko、Yamagishi Mai、Motomura Yasutaka、Kamatani Takashi、Oguchi Yusuke、Suzuki Nobutake、Kiniwa Tsuyoshi、Kabata Hiroki、Irie Misato、Tsunoda Tatsuhiko、Miya Fuyuki、Goda Keisuke、Ohara Osamu、Funatsu Takashi、Fukunaga Koichi、Moro Kazuyo、Uemura Sotaro、Shirasaki Yoshitaka
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 915-915

    • DOI

      10.1038/s42003-023-05297-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18232, KAKENHI-PROJECT-21H02750, KAKENHI-PROJECT-23K24342
  • [Journal Article] Upregulation of IL-4 receptor signaling pathway in circulating ILC2s from asthma patients2022

    • Author(s)
      Baba Rie、Kabata Hiroki、Shirasaki Yoshitaka、Kamatani Takashi、Yamagishi Mai、Irie Misato、Watanabe Risa、Matsusaka Masako、Masaki Katsunori、Miyata Jun、Moro Kazuyo、Uemura Sotaro、Fukunaga Koichi
    • Journal Title

      Journal of Allergy and Clinical Immunology: Global

      Volume: 1 Issue: 4 Pages: 299-304

    • DOI

      10.1016/j.jacig.2022.07.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08240, KAKENHI-PROJECT-21K18232, KAKENHI-PROJECT-23K24342
  • [Journal Article] Whole-embryonic identification of maternal microchimeric cell types in mouse using single-cell RNA sequencing2022

    • Author(s)
      Fujimoto Kana、Nakajima Akira、Hori Shohei、Tanaka Yumiko、Shirasaki Yoshitaka、Uemura Sotaro、Irie Naoki
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 18313-18313

    • DOI

      10.1038/s41598-022-20781-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18232, KAKENHI-PROJECT-21K19254, KAKENHI-PROJECT-22K19422, KAKENHI-PLANNED-22H05191, KAKENHI-PROJECT-21H04801
  • [Journal Article] Zero-mode waveguides and nanopore-based sequencing technologies accelerate single-molecule studies2022

    • Author(s)
      Ryo Iizuka, Hirohito Yamazaki, Sotaro Uemura
    • Journal Title

      Biophysics and Physicobiology

      Volume: 19 Issue: 0 Pages: n/a

    • DOI

      10.2142/biophysico.bppb-v19.0032

    • ISSN
      2189-4779
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K05310, KAKENHI-PROJECT-21K18232
  • [Journal Article] レーザートラップや蛍光を用いた1分子計測のタンパク質翻訳機構への応用2009

    • Author(s)
      上村想太郎
    • Journal Title

      BIO INDUSTRY 26

      Pages: 15-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Journal Article] レーザートラップや蛍光を用いた1分子計測のタンパク質翻訳機構への応用2009

    • Author(s)
      上村想太郎
    • Journal Title

      BIO INDUSTRY 26

      Pages: 15-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Journal Article] Single molecule force measurement for protein synthesis on the ribosome2008

    • Author(s)
      S. Uemura
    • Journal Title

      World Scientific

      Pages: 21-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Journal Article] Single molecule force measurement for protein synthesis on the ribosome2008

    • Author(s)
      S. Uemura
    • Journal Title

      World Scientific

      Pages: 21-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Journal Article] Single molecule imaging of full protein synthesis by immobilized ribosomes2008

    • Author(s)
      S. Uemura., R. lizuka., T. Ueno., Y. Shimizu., H. Taguchi., T. Ueda., J. D. Puglisi and T. Funatsu
    • Journal Title

      Nucleic Acids Research 36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Journal Article] タンパク質の翻訳と折りたたみ過程の1分子蛍光イメージング2008

    • Author(s)
      上村想太郎、船津高志
    • Journal Title

      ぶんせき 11

      Pages: 582-586

    • NAID

      10025215299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Journal Article] Single molecule imaging of full protein synthesis by immobilized ribosomes2008

    • Author(s)
      S. Uemura., R. lizuka., T. Ueno., Y. Shimizu., H. Taguchi., T. Ueda., J. D. Puglisi and T. Funatsu
    • Journal Title

      Nucleic Acids Research 36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Journal Article] タンパク質の翻訳と折りたたみ過程の1分子蛍光イメージング2008

    • Author(s)
      上村想太郎、船津高志
    • Journal Title

      ぶんせき 11

      Pages: 582-586

    • NAID

      10025215299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Journal Article] リボソームによるタンパク質合成の1分子力学測定による研究2007

    • Author(s)
      上村 想太郎
    • Journal Title

      Dojin News 124

      Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Journal Article] リボソームによるタンパク質合成の1分子力学測定による研究2007

    • Author(s)
      上村 想太郎
    • Journal Title

      Dojin News 124

      Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] A study on the structural dynamics of the nucleosome containing H2A.B using solid-state nanopores2022

    • Author(s)
      Hikaru Nozawa, Hirohito Yamazaki, Ryo Iizuka, Rina Hirano, Tomoya Kujirai, Hitoshi Kurumizaka, Sotaro Uemura
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Presentation] ナノポア計測によるCALHM2チャネルダイナミクスの解明2022

    • Author(s)
      中村宗太郎、山崎洋人、志甫谷渉、濡木理、上村想太郎
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] A study on the structural dynamics of the nucleosome containing H2A.B using solid-state nanopores2022

    • Author(s)
      Hikaru Nozawa, Hirohito Yamazaki, Ryo Iizuka, Rina Hirano, Tomoya Kujirai, Hitoshi Kurumizaka, Sotaro Uemura
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] Feasibility study of the method for obtaining fluorogenic RNA aptamers using water-in-oil microdroplets2022

    • Author(s)
      Keisuke Ito, Ryo Iizuka, Sotaro Uemura
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] ナノポア計測によるCALHM2チャネルダイナミクスの解明2022

    • Author(s)
      中村宗太郎、山崎洋人、志甫谷渉、濡木理、上村想太郎
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Presentation] Investigation of the effect of spherical (three-dimensional) confinement on the higher order structure of 12-mer nucleosome arrays2022

    • Author(s)
      Masahiro Okabe, Ryo Iizuka, Munetaka Akatsu, Kenta Echigoya, Tomoya Kujirai, Hitoshi Kurumizaka, Sotaro Uemura
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] Development of a single-particle inclusions detection method by solid-state nanopore for miRNA in single exosome detection2022

    • Author(s)
      Takumi Uchida, Hirohito Yamazaki, Ryo Iizuka, Sotaro Uemura
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Presentation] ショウジョウバエアルゴノート 2 の N 末端領域はアミロイド様凝集体を形成する(N-terminal region of Drosophila Argonaute2 can form amyloid-like aggregates)2022

    • Author(s)
      成田 晴香、島 知弘、飯塚 怜、塩見 美喜子、上村 想太郎
    • Organizer
      第21回東京大学生命科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] Development of a single-particle inclusions detection method by solid-state nanopore for miRNA in single exosome detection2022

    • Author(s)
      Takumi Uchida, Hirohito Yamazaki, Ryo Iizuka, Sotaro Uemura
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] Mitochondrial Translocation of Telomerase Reverse Transcriptase Changes Cell Death Process2021

    • Author(s)
      Hiroshi Ebata, Tomohiro Shima, Yoshitaka Shirasaki, Sotaro Uemura
    • Organizer
      Cell Bio Virtual 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] CALHM2をナノポアとして用いた多様なサイズの分子検出法の開発2021

    • Author(s)
      中村宗太郎、山崎洋人、志甫谷渉、濡木理、上村想太郎
    • Organizer
      第59回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Presentation] テロメラーゼ逆転写酵素TERTのミトコンドリア輸送の細胞死制御2021

    • Author(s)
      江端拓志, 島知弘, 白崎善隆, 上村想太郎
    • Organizer
      第44回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] Photothermally enhanced single molecule nanopore sensing2021

    • Author(s)
      Hirohito Yamazaki, Sotaro Uemura
    • Organizer
      第59回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Presentation] レーザー照射による固液界面でのリポソームの捕捉と破壊2021

    • Author(s)
      内田匠、山崎洋人、上村想太郎
    • Organizer
      第59回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Presentation] フォトサーマル効果を活用した一分子ナノポア計測技術の創出2021

    • Author(s)
      山崎洋人、上村想太郎
    • Organizer
      第82回 応用物理学会秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-21K18232
  • [Presentation] 出芽酵母の大規模な遺伝子解析のための高スループット細胞形態分取法2020

    • Author(s)
      H. Matsumura, A. Isozaki, Y. Zhao, K. Huang, T. Wakamiya, D. Yuan, H. Mikami, S. Ohnuki, S. Uemura, Y. Ohya, and K. Goda
    • Organizer
      化学とマイクロ・ナノシステム学会
    • Data Source
      KAKENHI-PROJECT-20H00317
  • [Presentation] タンパク質翻訳開始複合体における30S-mRNA結合力の1分子顕微解析2008

    • Author(s)
      増田智彰, 船津高志, 上村想太郎
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] 1分子計測技術の現状と展望2008

    • Author(s)
      上村想太郎
    • Organizer
      科学技術交流財団第5回研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-07
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] Single molecule measurement for protein synthesis2008

    • Author(s)
      S. Uemura
    • Organizer
      SSF-JST Joint Symposium
    • Place of Presentation
      ストックホルム、スウェーデン
    • Year and Date
      2008-05-26
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Presentation] ナノ開口基板上でのタンパク質翻訳中における高濃度tRNAの1分子ダイナミクス2008

    • Author(s)
      上村想太郎、清水義宏、飯塚怜、上田卓也、赤堀玲奈、島本直伸、谷井孝至、大泊巌、Joseph.D.Puglisi、船津高志
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] タンパク質翻訳開始複合体における30S-mRNA結合力の1分子顕微解析2008

    • Author(s)
      増田智彰, 船津高志, 上村想太郎
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Presentation] Single molecule imaging of full protein synthesis by immobilized ribosomes2008

    • Author(s)
      Sotaro Uemura
    • Organizer
      Biophysical Society Annual Meeting
    • Place of Presentation
      横浜
    • Year and Date
      2008-02-07
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] Single molecule imaging of full protein synthesis by immobilized ribosomes2008

    • Author(s)
      Sotaro Uemura
    • Organizer
      Biophysical Society Annual Meeting
    • Place of Presentation
      横浜
    • Year and Date
      2008-02-07
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Presentation] ナノ開口基板上でのタンパク質翻訳中における高濃度tRNAの1分子ダイナミクス2008

    • Author(s)
      上村想太郎、清水義宏、飯塚怜、上田卓也、赤堀玲奈、島本直伸、谷井孝至、大泊巌、Joseph. D. Puglisi、船津高志
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Presentation] タンパク質誕生の1分子イメージング2008

    • Author(s)
      上村想太郎
    • Organizer
      東大生命科学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] タンパク質誕生の1分子イメージング2008

    • Author(s)
      上村想太郎
    • Organizer
      東大生命科学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Presentation] 1分子計測技術の現状と展望2008

    • Author(s)
      上村想太郎
    • Organizer
      科学技術交流財団第5回研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-07
    • Data Source
      KAKENHI-PROJECT-19037009
  • [Presentation] Single molecule measurement for protein synthesis2008

    • Author(s)
      S. Uemura
    • Organizer
      SSF-JST Joint Symposium
    • Place of Presentation
      ストックホルム、スウェーデン
    • Year and Date
      2008-05-26
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] タンパク質翻訳におけるリボソームの分子モーターとしての役割2007

    • Author(s)
      上村 想太郎
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-23
    • Data Source
      KAKENHI-PROJECT-19042003
  • [Presentation] タンパク質翻訳におけるリボソームの分子モーターとしての役割2007

    • Author(s)
      上村 想太郎
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-23
    • Data Source
      KAKENHI-PROJECT-19037009
  • 1.  Goda Keisuke (70518696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  大矢 禎一 (20183767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  飯塚 怜
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  加畑 宏樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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