baba tomohisa 馬場智久

… Alternative Names

Baba Tomohisa 馬場智久

BABA Tomohisa 馬場智久

Less

Researcher Number	00452095
Other IDs
Affiliation (Current)	2025: 金沢大学, がん進展制御研究所, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 金沢大学, がん進展制御研究所, 准教授 2017 – 2018: 金沢大学, がん進展制御研究所, 准教授 2011 – 2016: 金沢大学, がん進展制御研究所, 助教 2007 – 2010: Kanazawa University, がん研究所, 助教
Review Section/Research Field	Principal Investigator Immunology / Basic Section 54010:Hematology and medical oncology-related / Experimental pathology Except Principal Investigator Basic Section 49030:Experimental pathology-related / Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 慢性骨髄性白血病 / 骨髄性白血病 / 炎症性ケモカイン / 造血幹細胞 / 白血病幹細胞 / 制御性T細胞 / 免疫寛容 / 樹状細胞 / 胸腺 / ジェロコンバージョン … More / 細胞老化 / 骨髄移植治療 / 白血病 / ドナー細胞由来白血病 / 造血幹細胞移植療法 / 細胞質内DNAセンサー / 細胞外小胞 / ケモカイン / 細胞間競合拮抗 / 細胞競合 / 骨髄 / 白血病前駆細胞 / 胸腺樹状細 / central tolerance / clonal deletion / 血中抗原 / CCR2 / 胸腺樹状細胞 / RAET1 / 腫瘍細胞 / perforin / granzyme / 抗腫瘍効果 / CD8 / CD4 / 細胞傷害活性 / 腫瘍免疫 / マクロファージ … More Except Principal Investigator マウス / 動脈硬化 / マクロファージ / 大動脈瘤 / ケモカイン / 生体分子 / 慢性骨髄性白血病 / BCR-ABL / 骨髄移植 / STING / ドナー細胞由来白血病 / 細胞外小胞 / 骨髄異形成症候群 Less

ジェロコンバージョンを分子基盤とした新規白血病分化誘導療法の開発Principal Investigator
- Principal Investigator
  
  馬場智久
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kanazawa University
Spacio-temporal analysis of the chemokine system during the course of aortic aneurysm formation
- Principal Investigator
  
  Mukaidaq Naofumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Wakayama Medical University
Pathophysiological role of extracellular vesicles in donor cell-derived leukemiaPrincipal Investigator
- Principal Investigator
  
  Baba Tomohisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kanazawa University
Elucidation of the roles of extracellular microsomes in donor cell-derived leukemia
- Principal Investigator
  
  Mukaida Naofumi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Internal medicine of the bio-information integration and related fields
- Research Institution
  Kanazawa University
Pathophysiological role of inflammatory chemokine, CCL3, in chronic myeloid leukemiaPrincipal Investigator
- Principal Investigator
  
  BABA Tomohisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kanazawa University
Pathophysiological interaction with normal bone marrow cells during the development of chronic myeloid leukemiaPrincipal Investigator
- Principal Investigator
  
  BABA Tomohisa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kanazawa University
Thymic Sirpα^<+>DC subset conducts the novel process of intrathymic immune tolerancePrincipal Investigator
- Principal Investigator
  
  BABA Tomohisa
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kanazawa University
Research of biological function and distinctive role of Sirp・^+ dendritic cells in central tolerancePrincipal Investigator
- Principal Investigator
  
  BABA Tomohisa
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kanazawa University
The cytotoxic mechanism and immunological role of CD4+CD8+ macrophagesPrincipal Investigator
- Principal Investigator
  
  BABA Tomohisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Immunology
- Research Institution
  Kanazawa University

[Book] 炎症と免疫 3月号2016
- Author(s)
  馬場智久
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-25460492
[Book] Cancer Targeted Drug Delivery2013
- Author(s)
  Mukaida N, Sasaki S, Baba T
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-25460492
[Journal Article] Autophagy Inhibition?induced Cytosolic DNA Sensing Combined with Differentiation Therapy Induces Irreversible Myeloid Differentiation in Leukemia Cells2024
- Author(s)
  Baba Tomohisa、Tomaru Utano、Hirao Atsushi、Mukaida Naofumi、Johmura Yoshikazu
- Journal Title
  
  Cancer Research Communications
  
  Volume: 4 Issue: 3 Pages: 849-860
- DOI
  10.1158/2767-9764.crc-23-0507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06966, KAKENHI-PROJECT-22K19398, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03835, KAKENHI-PROJECT-23K27376
[Journal Article] Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway2021
- Author(s)
  Baba Tomohisa、Yoshida Takeshi、Tanabe Yamato、Nishimura Tatsunori、Morishita Soji、Gotoh Noriko、Hirao Atsushi、Hanayama Rikinari、Mukaida Naofumi
- Journal Title
  
  Cell Death & Disease
  
  Volume: 12 Issue: 4 Pages: 322-322
- DOI
  10.1038/s41419-021-03587-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08749, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-19K22557, KAKENHI-PUBLICLY-20H05029, KAKENHI-PROJECT-21H02761
[Journal Article] CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis2021
- Author(s)
  Zoshima T, Baba T, Tanabe Y, Ishida Y, Nakatani K, Nagata M, Mukaida N, Kawano M.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: － Issue: 7 Pages: 3033-3048
- DOI
  10.1093/rheumatology/keab825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17424, KAKENHI-PROJECT-20K08749, KAKENHI-PROJECT-21K06966
[Journal Article] Involvement of a Transcription factor, Nfe2, in Breast Cancer Metastasis to Bone2020
- Author(s)
  Di Zhang, Sadahiro Iwabuchi, Tomohisa Baba, Shin-Ichi Hashimoto, Naofumi Mukaida, So-Ichiro Sasaki
- Journal Title
  
  Cancers (Basel)
  
  Volume: 12 Issue: 10 Pages: 3003-3003
- DOI
  10.3390/cancers12103003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07567, KAKENHI-PROJECT-20K08749
[Journal Article] Expansion of senescent megakaryocyte-lineage cells maintains CML cell leukemogenesis2020
- Author(s)
  Tanabe Yamato、Kawamoto Shimpei、Takaku Tomoiku、Morishita Soji、Hirao Atsushi、Komatsu Norio、Hara Eiji、Mukaida Naofumi、Baba Tomohisa
- Journal Title
  
  Blood Advances
  
  Volume: 4 Issue: 24 Pages: 6175-6188
- DOI
  10.1182/bloodadvances.2020003117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07446, KAKENHI-PROJECT-20K08749, KAKENHI-PROJECT-19H01033
[Journal Article] Two-Faced Roles of Tumor-Associated Neutrophils in Cancer Development and Progression2020
- Author(s)
  Mukaida Naofumi、Sasaki So-ichiro、Baba Tomohisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 10 Pages: 3457-3457
- DOI
  10.3390/ijms21103457
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08749
[Journal Article] Alveolar macrophages drive hepatocellular carcinoma lung metastasis by generating leukotriene B4.2018
- Author(s)
  Nosaka T, Baba T, Tanabe Y, Sasaki S, Nishimura T, Imamura Y, Yurino H, Hashimoto S, Arita M, Nakamoto Y, Mukaida N.
- Journal Title
  
  J Immunol
  
  Volume: 200 Issue: 5 Pages: 1839-1852
- DOI
  10.4049/jimmunol.1700544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08733, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17J06054, KAKENHI-PROJECT-17K19681, KAKENHI-PROJECT-17H01540
[Journal Article] Lung Macrophages: Multifunctional Regulator Cells for Metastatic Cells.2018
- Author(s)
  Mukaida N, Nosaka T, Nakamoto Y, Baba T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 20 Issue: 1 Pages: 116-116
- DOI
  10.3390/ijms20010116
- NAID
  120006996023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08733, KAKENHI-PROJECT-17K19681
[Journal Article] Involvement of prokineticin 2-expressing neutrophil infiltration in 5-fluorouracil-induced aggravation of breast cancer metastasis to lung.2018
- Author(s)
  Sasaki S, Baba T, Muranaka H, Tanabe Y, Takahashi C, Matsugo S, Mukaida N.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 印刷中 Issue: 7 Pages: 1515-1525
- DOI
  10.1158/1535-7163.mct-17-0845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08733, KAKENHI-PROJECT-17K07159, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17J06054, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K19681, KAKENHI-PROJECT-18K15237
[Journal Article] Chemokines as a conductor of bone marrow microenvironment in chronic myeloid leukemia.2017
- Author(s)
  Mukaida N, Tanabe Y, Baba T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 8 Pages: 1824-1824
- DOI
  10.3390/ijms18081824
- NAID
  120006374156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08733, KAKENHI-PROJECT-17K19681, KAKENHI-PROJECT-17J06054
[Journal Article] Gemcitabine induces cell senescence in human pancreatic cancer cell lines.2016
- Author(s)
  Song Y, Baba T, Mukaida N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 477 Issue: 3 Pages: 515-519
- DOI
  10.1016/j.bbrc.2016.06.063
- NAID
  120005830582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08733
[Journal Article] Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis.2016
- Author(s)
  Sasaki S, Baba T, Nishimura T, Hayakawa Y, Hashimoto S, Gotoh N, Mukaida N.
- Journal Title
  
  Cancer Lett.
  
  Volume: 378 Issue: 1 Pages: 23-32
- DOI
  10.1016/j.canlet.2016.05.005
- NAID
  120005764205
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18406, KAKENHI-PROJECT-16K08733
[Journal Article] Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation.2016
- Author(s)
  Tanabe Y, Sasaki S, Mukaida N, Baba T.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 30 Pages: 48335-345
- DOI
  10.18632/oncotarget.10227
- NAID
  120006996025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18406, KAKENHI-PROJECT-16K08733
[Journal Article] MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice.2016
- Author(s)
  Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N
- Journal Title
  
  Blood
  
  Volume: 印刷中 Issue: 21 Pages: 2607-17
- DOI
  10.1182/blood-2015-10-673087
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K20969, KAKENHI-PUBLICLY-15H01509, KAKENHI-PUBLICLY-16H01199, KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-16K08733
[Journal Article] MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice.2016
- Author(s)
  Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N.
- Journal Title
  
  Blood
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460492
[Journal Article] High-dose cyclophosphamide induces specific tumor immunity with concomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites.2015
- Author(s)
  Naito, T., Baba, T., Takeda, K., Sasaki, S., Nakamoto, Y. and Mukaida, N.
- Journal Title
  
  Cancer Letters
  
  Volume: 366 Issue: 1 Pages: 93-99
- DOI
  10.1016/j.canlet.2015.06.009
- NAID
  120005663501
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14410, KAKENHI-PROJECT-26670379, KAKENHI-PROJECT-15K18406, KAKENHI-PROJECT-25460492, KAKENHI-PROJECT-25293171
[Journal Article] Gemcitabine-induced CXCL8 expression counteracts its actions by inducing tumor neovascularization.2015
- Author(s)
  Song Y, Baba T, Li YY, Furukawa K, Tanabe Y, Matsugo S, Sasaki S, Mukaida N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 458 Issue: 2 Pages: 341-346
- DOI
  10.1016/j.bbrc.2015.01.112
- NAID
  120005593940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460492, KAKENHI-PROJECT-15K18406
[Journal Article] Ag and IL-2 immune complexes efficiently expand Ag-specific Treg cells that migrate in response to chemokines and reduce localized immune responses.2014
- Author(s)
  Hamano R, Baba T, Sasaki S, Tomaru U, Ishizu A, Kawano M, Yamagishi M, Mukaida N
- Journal Title
  
  Eur J Immunol
  
  Volume: 44 Issue: 4 Pages: 1005-1015
- DOI
  10.1002/eji.201343434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659171, KAKENHI-PROJECT-24700973, KAKENHI-PROJECT-25460489, KAKENHI-PROJECT-25460492, KAKENHI-PROJECT-25461181, KAKENHI-PROJECT-26860748
[Journal Article] Role of macrophage inflammatory protein (MIP)-1α/CCL3 in leukemogenesis.2014
- Author(s)
  Baba T, Mukaida N.
- Journal Title
  
  Mol Cell Oncol
  
  Volume: 1 Issue: 1 Pages: e29899-e29899
- DOI
  10.4161/mco.29899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460492
[Journal Article] Crucial Involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice.2014
- Author(s)
  Sasaki S, Baba T, Shinagawa K, Matsushima K, Mukaida N.
- Journal Title
  
  Int J Cancer.
  
  Volume: In press Issue: 6 Pages: 1297-1306
- DOI
  10.1002/ijc.28779
- NAID
  120005463351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700973, KAKENHI-PROJECT-25460492
[Journal Article] MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.2013
- Author(s)
  Baba T, Naka K, Morishita S, Komatsu N, Hirao A, Mukaida N.
- Journal Title
  
  J Exp Med.
  
  Volume: 210 Issue: 12 Pages: 2661-2673
- DOI
  10.1084/jem.20130112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PUBLICLY-25118725, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25460492
[Journal Article] Chemokines in tumor development and progression2012
- Author(s)
  Mukaida N, Baba T
- Journal Title
  
  Experimental Cell Research
  
  Volume: 318(Invited Review) Issue: 2 Pages: 95-102
- DOI
  10.1016/j.yexcr.2011.10.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390117, KAKENHI-PROJECT-23790532
[Journal Article] Novel process of intrathymic tumor-immune tolerance through CCR2-mediated recruitment of Sirp α+dendritic cells :a murine model2012
- Author(s)
  Baba, T., Badr Mel, S., Tomaru, U., Ishizu, A., Mukaida, N
- Journal Title
  
  PLoS ONE
  
  Volume: 7(7) Issue: 7 Pages: e41154-e41154
- DOI
  10.1371/journal.pone.0041154
- NAID
  120004419373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590353, KAKENHI-PROJECT-23790532, KAKENHI-PROJECT-24659171
[Journal Article] Decrease of peripheral and intestinal NKG2A-positive T cells in patients with ulcerative colitis2012
- Author(s)
  Katsurada, T., Kobayashi, W., Tomaru, U.,Baba, T., Furukawa, S., Ishizu, A., Takeda, K., Sakamoto, N., Asaka, M., Takeda, H. and Kasahara, M
- Journal Title
  
  PLoS ONE7
  
  Volume: (9) Issue: 9 Pages: e44113-e44113
- DOI
  10.1371/journal.pone.0044113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590353, KAKENHI-PROJECT-23659195, KAKENHI-PROJECT-23790532, KAKENHI-PROJECT-24390091, KAKENHI-PROJECT-24659171
[Journal Article] Identification of a phenanthrene derivative as a potent anti-cancer drug with Pim kinase inhibitory activities2012
- Author(s)
  Wang Y-Y, Taniguchi T, Baba T, Li Y-Y, Ishibashi H, and Mukaida N
- Journal Title
  
  Cancer Sci
  
  Volume: 103(1) Issue: 1 Pages: 107-115
- DOI
  10.1111/j.1349-7006.2011.02117.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390117, KAKENHI-PROJECT-23790532
[Journal Article] Ablation of the Ccr2 gene exacerbates polyarthritis in interleukin-1 receptor antagonist-deficient mice.2011
- Author(s)
  Fujii H, Baba T, Ishida Y, Kondo T, Yamagishi M, Kawano M, Mukaida N.
- Journal Title
  
  Arthritis Rheum. 63
  
  Pages: 96-106
- NAID
  120002754103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Ablation of the Ccr2 gene exacerbates polyarthritis in interleukin-1 receptor antagonist-deficient mice.2011
- Author(s)
  Fujii H, Baba T, Ishida Y, Kondo T, Yamagishi M, Kawano M, Mukaida N
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Pages: 96-106
- NAID
  120002754103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Accelerated hepatocellular carcinoma development in mice expres sing the Pim-3 transgene selectively in the liver.2010
- Author(s)
  Wu Y, Wang YY, Nakamoto Y, Li YY, Baba T, Kaneko S, Fujii C, Mukaida N
- Journal Title
  
  Oncogene (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Crucial involvement of the CX3CR1-CX3CL1 axis in dextran sulfate sodium-mediated acute colitis in mice.2010
- Author(s)
  Kostadinova FI, Baba T, Ishida Y, Kondo T, Popivanova BK, Mukaida N.
- Journal Title
  
  J Leukoc Biol. 88
  
  Pages: 133-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Antitumor effect after radiofrequency ablation of murine hepatoma is augmented by an active variant of CC Chemokine ligand 3/macrophage inflammatory protein-lalpha.2010
- Author(s)
  Iida N, Nakamoto Y, Baba T, Nakagawa H, Mizukoshi E, Naito M, Mukaida N, Kaneko S.
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 6556-6565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Crucial involvement of the CX3CR1-CX3CL1 axis in dextran sulfate sodium-mediated acute colitis in mice.2010
- Author(s)
  Kostadinova FI, Baba T, Ishida Y, Kondo T, Popivanova BK, Mukaida N
- Journal Title
  
  J Leukoc Biol
  
  Volume: 88 Pages: 133-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR 2-dependent manner.2009
- Author(s)
  Baba T, Nakamoto Y, Mukaida N
- Journal Title
  
  J Immunol 183
  
  Pages: 3053-3063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Essential contribution of Ets-1 to constitutive Pim-3 expressi on in human pancreatic cancer cells.2009
- Author(s)
  Li YY, Wu Y, Tsuneyama K, BabaT, Mukaida N.
- Journal Title
  
  Cancer science 100
  
  Pages: 396-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890081
[Journal Article] Identification of stemonamide synthetic intermediates as a novel potent anticancer drug with an apoptosis-inducing ability.2009
- Author(s)
  Li YY, Wang YY, Taniguchi T, Kawa Kami T, Baba T, Ishibashi H, Mukaida N
- Journal Title
  
  Int J Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR2-dependent manner.2009
- Author(s)
  Baba T, Nakamoto Y, Mukaida N.
- Journal Title
  
  J Immunol. 183
  
  Pages: 3053-3063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790464
[Journal Article] Protective Roles of the Fractalkine/CX3CL1-CX3CR1 Interactions in Alkali-Induced Corneal Neovascularization through Enhanced Antiangiogenic Factor Expression.2008
- Author(s)
  Lu P, Li L, Kuno K, Wu Y, Baba T, Li YY, Zhang X, Mukaida N
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 4283-4291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890081
[Journal Article] CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung me tastasis process.2008
- Author(s)
  Wu Y, Li YY, Matsushirma K, Baba T, Mukaida N.
- Journal Title
  
  Journal of Immunology 181
  
  Pages: 6384-6394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890081
[Journal Article] Tumor cell apoptosis induces tumor-specific immunity in a CC chemokine receptor 1- and 5-dependent manner in mice.2008
- Author(s)
  Iida N, Nakamoto Y, Baba T, Kakinoki K, Li YY, Wu Y, Matsushima K, Kaneko S, Mukaida N.
- Journal Title
  
  Journal of Leukocyte Biology 84
  
  Pages: 1001-1010
- NAID
  120000997200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890081
[Journal Article] Rat CD4+CD8+ Macrophages Kill Tumor Cells through an NKG2D- and Granzyme/Perforin-Dependent2008
- Author(s)
  Baba T, Iwasaki S, Maruoka T, Suzuki A, Tomaru U, Ikeda H, Yoshiki T, Kasahara M, Ishizu A
- Journal Title
  
  Mechanism. J. Immunol 180
  
  Pages: 2999-3006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890081
[Journal Article] CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process2008
- Author(s)
  Wu Y, Li YY, Matsushima K, Baba T, Mukaida N
- Journal Title
  
  J. Immunol 181
  
  Pages: 6384-6394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890081
[Journal Article] Rat CD4+CD8+ Macrophages Kill Tumor Cells through an NKG2D- and Granzyme/Perforin-Dependent Mechanism.2008
- Author(s)
  Baba T, Iwasaki S, Maruoka T, Suzuki A, Tomaru U, Ikeda H, Yoshiki T, Kasahara M, Ishizu A
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 2999-3006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890081
[Patent] 慢性骨髄性白血病治療剤及び該治療剤をスクリーニングする方法2016
- Inventor(s)
  向田直史、馬場智久
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-025365
- Filing Date
  2016-02-12
- Data Source
  KAKENHI-PROJECT-25460492
[Patent] 慢性骨髄性白血病モデル動物2013
- Inventor(s)
  馬場　智久、　　向田　直史
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-011556
- Filing Date
  2013-01-24
- Data Source
  KAKENHI-PROJECT-23790532
[Patent] 慢性骨髄性白血病モデル動物2013
- Inventor(s)
  馬場智久, 向田直史
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2013-011556
- Filing Date
  2013-01-24
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] Cytosolic DNA-sensor signaling potentiates AML differentiation therapy to induce an irreversible cell differentiation.2022
- Author(s)
  馬場智久、城村由和
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08749
[Presentation] Autophagy inhibitor selectively induces cytotoxicity against myeloid leukemia cells by accumulating cytosolic DNA.2021
- Author(s)
  馬場智久
- Organizer
  第80回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08749
[Presentation] 慢性骨髄性白血病のTKI治療に対するオートファジー阻害剤の併用効果2020
- Author(s)
  馬場智久、向田直史
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08749
[Presentation] Pathogenic role of leukemia cell-derived extracellular vesicles in donor cell-derived leukemia after BM transplantation.2018
- Author(s)
  Baba T, Mukaida N.
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08733
[Presentation] BCR-ABL, an oncogene of chronic myeloid leukemia, can induce cellular senescence2018
- Author(s)
  Tanabe Y, Baba T, and Mukaida N
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19681
[Presentation] 慢性骨髄性白血病におけるケモカインCCL3を介した正常・白血病性造血間でのクロストーク2018
- Author(s)
  馬場智久
- Organizer
  第107回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19681
[Presentation] Pathogenic role of leukemia cell-derived extracellular vesicles in donor cell-derived leukemia after BM transplantation2018
- Author(s)
  Baba T and Mukaida N
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19681
[Presentation] 慢性骨髄性白血病におけるケモカインCCL3を介した正常・白血病性造血間でのクロストーク2018
- Author(s)
  馬場智久
- Organizer
  日本病理学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08733
[Presentation] rucial roles of LAMP1/CD107a-expressing CD4-positive T cells in high-dose cyclophosphamide-induced specific tumor immunity2018
- Author(s)
  Mukaida N, Naito T, Nakamoto Y, and Baba T
- Organizer
  45th Naito Conference on Immunological and Molecular Bases for Cancer Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19681
[Presentation] Pathological contribution of an inflammatory chemokine CCL3 in chronic myeloid leukemia as a stem cell inhibitor.2017
- Author(s)
  Baba T and Mukaida N
- Organizer
  5th Annual Meeting of the International Cytokine and Interferon Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19681
[Presentation] Context-dependent diverse roles of CCR5-mediated signals in chronic myeloid leukemia (CML) pathogenesis2017
- Author(s)
  Tanabe Y, Baba T, and Mukaida, N.
- Organizer
  5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19681
[Presentation] Context-dependent diverse roles of CCR5-mediated signals in chronic myeloid leukemia (CML) pathogenesis.2017
- Author(s)
  Tanabe Y, Baba T, Mukaida N.
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08733
[Presentation] Pathological contribution of an inflammatory chemokine CCL3 in chronic myeloid leukemia as a stem cell inhibitor.2017
- Author(s)
  Baba T, Mukaida N.
- Organizer
  5th Annual meeting of the international cytokine and interferon society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08733
[Presentation] CCL3-expressing basophil-like leukemia cells drive the pathogenesis of chronic myeloid leukemia.2016
- Author(s)
  Baba T.
- Organizer
  International Symposium on Tumor Biology in Kanazawa
- Place of Presentation
  金沢大学医学部記念館（金沢）
- Year and Date
  2016-04-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08733
[Presentation] CCL3-expressing basophil-like leukemia cells conduct leukemic hematopoiesis in chronic myeloid leukemia.2016
- Author(s)
  Baba T, Tanabe Y, Mukaida N.
- Organizer
  The 5th JCA-AACR Special Joint Conference
- Place of Presentation
  東京ベイ舞浜ホテル（千葉）
- Year and Date
  2016-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08733
[Presentation] CCL3-expressing basophil-like leukemia cells drive leukemia-tropic hematopoiesis in chronic myeloid leukemia.2016
- Author(s)
  Baba T, Tanabe Y, Mukaida N.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08733
[Presentation] Role of inflammatory chemokine, CCL3, in the dominant proliferation of leukemia initiating cells in CML BM.2015
- Author(s)
  Baba T, Mukaida N.
- Organizer
  12th World Congress on Inflammation
- Place of Presentation
  Seaport Hotel and World Trade Center (Boston)
- Year and Date
  2015-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460492
[Presentation] Crucial role of MIP-1α/CCL3 in the crosstalk between normal and leukemic hematopoiesis in chronic myeloid leukemia.2015
- Author(s)
  Baba T, Mukaida N.
- Organizer
  日本免疫学会総会
- Place of Presentation
  Sapporo Convention Center (札幌)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25460492
[Presentation] Inflammatory chemokine, CCL3, conducts the dominant proliferation of leukemia cells in CML BM.2015
- Author(s)
  Baba T, Mukaida N.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  Nagoya Congress Center (名古屋)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460492
[Presentation] Role of a stem cell inhibitory chemokine, CCL3, in the　pathophysiology of chronic myeloid leukemia2014
- Author(s)
  Tomohisa Baba
- Organizer
  第4回金沢大学ーFudan Universtiyジョイントシンポジウム
- Place of Presentation
  Fudan University (上海)
- Year and Date
  2014-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-25460492
[Presentation] 慢性骨髄性白血病発症過程における炎症性ケモカインCCL3による白血病幹細胞の維持2013
- Author(s)
  馬場　智久
- Organizer
  日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25460492
[Presentation] Inflammatory chemokines, MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.2013
- Author(s)
  馬場　智久
- Organizer
  日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-25460492
[Presentation] Novel process of intrathymic immune tolerance against secretory tumorspecific antigens2012
- Author(s)
  馬場智久, 向田直史
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] Thymic Sirp alpha+ DC subset conducts the novel process of intrathymic tumor-immune tolerance2012
- Author(s)
  馬場智久, 向田直史
- Organizer
  第71回日本癌学会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] Intrathymic perivascular dendritic 図2 血中抗原に対するcentral toleranceの誘導 cells capturing blood-borne antigens conduct central tolerance2011
- Author(s)
  馬場智久, 向田直史
- Organizer
  第6回研究所ネットワーク国際シンポジウム
- Place of Presentation
  東京医科歯科大学(東京都)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] Intrathymic perivascular dendritic cells capturing blood-borne antigens conduct central tolerance2011
- Author(s)
  馬場　智久
- Organizer
  研究所ネットワーク国際シンポジウム
- Place of Presentation
  東京医科歯科大学（東京都）
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] 胸腺perivascular DCによる血中抗原の取り込みと制御性T細胞の分化誘導2011
- Author(s)
  馬場　智久
- Organizer
  日本免疫学会
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] Thymic Sirpα+ conventional dendritic cells orchestrate central tolerance system against blood borne antigens.2010
- Author(s)
  Baba T, Mukaida N
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸国際会議場(兵庫県)(招待講演)
- Data Source
  KAKENHI-PROJECT-21790464
[Presentation] Thymic Sirp・+ c onventional dendritic cells orchest rate central tolerance system again st blood-borne antigens.2010
- Author(s)
  Baba T, Mukaida N.
- Organizer
  14^<th> Intern ational Congress of Immunology
- Place of Presentation
  神戸国際会議場(兵庫)
- Data Source
  KAKENHI-PROJECT-21790464
[Presentation] Establishment of central tolerance against blood-borne antigens by thymic Sirpα+ conventional dendritic cells.2010
- Author(s)
  Baba T, Mukaida N
- Organizer
  97^<th> Annual Meeting of American Association of Immunologists
- Place of Presentation
  Baltimore Convention Center (USA)(招待講演)
- Data Source
  KAKENHI-PROJECT-21790464
[Presentation] Establishment of central tolerance against blood-bo rne antigens by thymic Sirp・+ conv entional dendritic cells.2010
- Author(s)
  Baba T, Mukaida N.
- Organizer
  97^<th> Annual Meeting of American Asso ciation of Immunologists
- Place of Presentation
  Baltimore Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-21790464
[Presentation] Thymic Sirp alpha+ conventional dendritic cell is a major generator of central tolerance against blood-borne antigens2009
- Author(s)
  Baba T, Mukaida N
- Organizer
  日本免疫学会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21790464
[Presentation] Crucial contribution of thymic Sirpα+ conventional dendritic cells to central tolerance against blood-borne antigens2009
- Author(s)
  Baba T, Mukaida N
- Organizer
  17^<th> International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  KKRホテル金沢(石川)
- Data Source
  KAKENHI-PROJECT-21790464
[Presentation] CD4/CD8 double positive マクロファージの発見と自然免疫系における新しいエフェクター細胞としての展開2008
- Author(s)
  馬場智久
- Organizer
  日本病理学会
- Place of Presentation
  金沢
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19890081
[Presentation] 血中抗原に対する免疫寛容誘導に関わるSirpa+胸腺樹状細胞の役割2008
- Author(s)
  馬場智久, 呉俣, 向田直史
- Organizer
  日本免疫学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19890081
[Presentation] CD4+/CD8+ マクロファージの抗腫瘍メカニズム2007
- Author(s)
  Iwasaki S, Baba T, and lshizu A
- Organizer
  日本免疫学会(poster presentation)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19890081
[Presentation] CD4/CD8 double positiveマクロファージによる抗腫瘍メカニズムの解明2007
- Author(s)
  馬場智久
- Organizer
  日本病理学会
- Place of Presentation
  大阪
- Year and Date
  2007-03-14
- Data Source
  KAKENHI-PROJECT-19890081
[Presentation] CD4/CD8 double-positive monocytes/ macrophages : a subpopulation of the macrophage/dendritic cell lineage with a cytotoxic phenotype2007
- Author(s)
  馬場智久
- Organizer
  16^<th> International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  静岡
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19890081
[Presentation] CD4/CD8 double-positive monocytes/macrophages:a subpopulation of the macrophage/dendritic cedll lineage with a cytotoxic phenotype2007
- Author(s)
  Baba T and Ishizu A
- Organizer
  16th International Symposium on Molecular Cell Biology of Macrophages 2007 (poster presentation)
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-19890081
[Presentation] Establishment of CML mouse model to examine the interactive role of normal hematopoietic system on the pathophysiology
- Author(s)
  馬場　智久
- Organizer
  3rd International Symposium on Carcinogenic Spiral and International Symposium on Tumor Biology in Kanazawa
- Place of Presentation
  エクセルホテル東急（石川県）
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] Thymic Sirp alpha+ DC subset conducts the novel process of intrathymic tumor-immune tolerance
- Author(s)
  馬場　智久
- Organizer
  日本癌学会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23790532
[Presentation] Novel process of intrathymic immune tolerance against secretory tumor-specific antigens
- Author(s)
  馬場　智久
- Organizer
  日本免疫学会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23790532

1. Mukaida Naofumi (30182067)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. 石津明洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. 外丸詩野

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 佐々木宗一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. 竹田和由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 藏島乾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 河本新平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 山西吉典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 小松則夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

baba tomohisa 馬場 智久

Baba Tomohisa 馬場 智久

BABA Tomohisa 馬場 智久

Research Projects

Research Products

Co-Researchers

ジェロコンバージョンを分子基盤とした新規白血病分化誘導療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Spacio-temporal analysis of the chemokine system during the course of aortic aneurysm formation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological role of extracellular vesicles in donor cell-derived leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the roles of extracellular microsomes in donor cell-derived leukemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiological role of inflammatory chemokine, CCL3, in chronic myeloid leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiological interaction with normal bone marrow cells during the development of chronic myeloid leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Thymic Sirpα^<+>DC subset conducts the novel process of intrathymic immune tolerancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research of biological function and distinctive role of Sirp・^+ dendritic cells in central tolerancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The cytotoxic mechanism and immunological role of CD4+CD8+ macrophagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 炎症と免疫 3月号2016

Author(s)

Publisher

Data Source

[Book] Cancer Targeted Drug Delivery2013

Author(s)

Publisher

Data Source

[Journal Article] Autophagy Inhibition?induced Cytosolic DNA Sensing Combined with Differentiation Therapy Induces Irreversible Myeloid Differentiation in Leukemia Cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis2021

Author(s)

baba tomohisa 馬場智久

Baba Tomohisa 馬場智久

BABA Tomohisa 馬場智久