Kitajima Shojiro 北島正二朗

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KITAJIMA Shojiro 北島正二朗

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Researcher Number	00452590
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 政策・メディア研究科(藤沢), 特任講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 慶應義塾大学, 政策・メディア研究科(藤沢), 特任講師 2007 – 2009: Hiroshima University, 大学院・医歯薬学総合研究科, 助教 2008: 広島大, 医歯(薬)学総合研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Morphological basic dentistry Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 細胞代謝 / リン酸化 / 細胞分裂 / ユビキチン / 細胞周期 / がん細胞の増殖 / メタボローム / 癌幹細胞 / がん幹細胞 / 脱リン酸化 / 口腔癌 / PP2A / Aurora-A … More Except Principal Investigator … More 顎顔面形成不全 / 第1咽頭弓 / 顎顔面形成異常 / ソニックヘッジホッグ / 顎顔面形成 / FAT1 / 幹細胞 / eR1活性細胞 / 膵再生医療 / 膵幹細胞 / 未分化能 / 未分化能維持 / 分化 / 多能性幹細胞 / Aurora-B Less

ムチン酸によるがん細胞増殖メカニズムの解明Principal Investigator
- Principal Investigator
  
  北島正二朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
新たな膵再生医療の構築に向けたeR1活性細胞の幹細胞機能の解析
- Principal Investigator
  
  山村明寛
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
Elucidation of the molecular mechanism of maxillofacial hypoplasia caused by FAT1 gene mutation
- Principal Investigator
  
  KUDO Yasusei
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  The University of Tokushima
Identifying functional metabolites that decide cell fates of cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  KITAJIMA Shojiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
Clarification of the mechanism on differentiation of pluripotent stem cells by Aurora-B and its application to regeneration therapy
- Principal Investigator
  
  KUDO Yasusei
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  The University of Tokushima
Aurora-A ; Phosphoregulation and its abnormality in Oral CancerPrincipal Investigator
- Principal Investigator
  
  KITAJIMA Shojiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
口腔癌におけるリン酸化異常に起因するSkp2過剰発現機構の解明Principal Investigator
- Principal Investigator
  
  北島正二朗
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University

All 2023 2022 2021 2020 2009 2008 2007

All Journal Article Presentation

[Journal Article] Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation2023
- Author(s)
  Ikizawa Takeshi、Ikeda Kazutaka、Arita Makoto、Kitajima Shojiro、Soga Tomoyoshi、Ichijo Hidenori、Naguro Isao
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 2 Pages: 102837-102837
- DOI
  10.1016/j.jbc.2022.102837
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19324, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-20K07598, KAKENHI-PROJECT-23K24024
[Journal Article] AGE/RAGE axis regulates reversible transition to quiescent states of ALK-rearranged NSCLC and pancreatic cancer cells in monolayer cultures2022
- Author(s)
  Kadonosono Tetsuya、Miyamoto Kotaro、Sakai Shiori、Matsuo Yoshiyuki、Kitajima Shojiro、Wang Qiannan、Endo Minori、Niibori Mizuho、Kuchimaru Takahiro、Soga Tomoyoshi、Hirota Kiichi、Kizaka-Kondoh Shinae
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1
- DOI
  10.1038/s41598-022-14272-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07598
[Journal Article] A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition2021
- Author(s)
  Kitajima Shojiro、Sun Wendi、Lee Kian Leong、Ho Jolene Caifeng、Oyadomari Seiichi、Okamoto Takashi、Masai Hisao、Poellinger Lorenz、Kato Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 4538-4538
- DOI
  10.1038/s41598-021-83857-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07598, KAKENHI-PROJECT-17H01418, KAKENHI-PUBLICLY-20H05399, KAKENHI-PUBLICLY-21H00264, KAKENHI-PROJECT-20K21410, KAKENHI-PROJECT-20KK0157, KAKENHI-PROJECT-20H00463
[Journal Article] Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia2020
- Author(s)
  Zhang Chujing、Amanda Stella、Wang Cheng、Tan Tze King、Ali Muhammad Zulfaqar、Leong Wei Zhong、Ng Ley Moy、Kitajima Shojiro、Li Zhenhua、Yeoh Allen Eng Juh、Tan Shi Hao、Sanda Takaomi
- Journal Title
  
  Haematologica
  
  Volume: 105 Issue: 6 Pages: 1545-1558
- DOI
  10.3324/haematol.2019.245639
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07598
[Journal Article] Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer.2007
- Author(s)
  Shojiro Kitajima
- Journal Title
  
  PLoS ONE 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890136
[Presentation] がん幹細胞の低栄養ストレス応答におけるメタボローム動態と増殖を促進するフェイト・メタボライトのスクリーニング2022
- Author(s)
  北島正二朗，山口裕々，冨田勝，曽我朋義
- Organizer
  第45回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07598
[Presentation] B56alpha-PP2A regulates chromosome alignment and stability2009
- Author(s)
  北島正二朗
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20791338
[Presentation] Overexpression of Aurora-A Caused by Constitutive Phosphorylation of Ser51.2008
- Author(s)
  Shojiro Kitajima
- Organizer
  先端歯学国際教育研究ネットワーク・日英シンポジウム
- Place of Presentation
  東京ガーデンパレスホテル(東京)
- Year and Date
  2008-02-04
- Data Source
  KAKENHI-PROJECT-19890136
[Presentation] リン酸化制御異常によるAurora-Aの安定化と過剰発現2007
- Author(s)
  北島正二朗
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19890136
[Presentation] 口腔癌におけるリン酸化制御異常を介したAurora-Aの過剰発現機構2007
- Author(s)
  北島正二朗
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  北海道大学(札幌)
- Data Source
  KAKENHI-PROJECT-19890136

1. KUDO Yasusei (50314753)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 曽我朋義 (60338217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 山村明寛 (30814678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 坂田直昭 (50431565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大里元美 (90314286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 毛利安宏 (80464353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 名黒功

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kitajima Shojiro 北島 正二朗

KITAJIMA Shojiro 北島 正二朗

Research Projects

Research Products

Co-Researchers

ムチン酸によるがん細胞増殖メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新たな膵再生医療の構築に向けたeR1活性細胞の幹細胞機能の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism of maxillofacial hypoplasia caused by FAT1 gene mutation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identifying functional metabolites that decide cell fates of cancer stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of the mechanism on differentiation of pluripotent stem cells by Aurora-B and its application to regeneration therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Aurora-A ; Phosphoregulation and its abnormality in Oral CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

口腔癌におけるリン酸化異常に起因するSkp2過剰発現機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] AGE/RAGE axis regulates reversible transition to quiescent states of ALK-rearranged NSCLC and pancreatic cancer cells in monolayer cultures2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer.2007

Author(s)

Journal Title

Data Source

[Presentation] がん幹細胞の低栄養ストレス応答におけるメタボローム動態と増殖を促進するフェイト・メタボライトのスクリーニング2022

Author(s)

Organizer

Data Source

[Presentation] B56alpha-PP2A regulates chromosome alignment and stability2009

Author(s)

Organizer

Place of Presentation

Year and Date

Kitajima Shojiro 北島正二朗

KITAJIMA Shojiro 北島正二朗