Nishimura Akiyuki 西村明幸

Researcher Number	00457152
Other IDs
Affiliation (Current)	2025: 生理学研究所, 生体機能調節研究領域, 特任准教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 生理学研究所, 生体機能調節研究領域, 特任准教授 2018 – 2021: 九州大学, 薬学研究院, 講師 2016 – 2017: 生理学研究所, 生体機能調節研究領域, 特任助教 2014 – 2015: 生理学研究所, 生体情報研究系, 特任助教
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Basic Section 59040:Nutrition science and health science-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Transformative Research Areas, Section (III) / Basic Section 47040:Pharmacology-related / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 心疾患 / ミトコンドリア / ミトコンドリア品質 / レドックス / G蛋白質共役型受容体 / 超硫黄分子 / 代謝柔軟性 / 慢性疾患 / 環境ストレス / 環境化学物質 … More / ストレス適応 / 心臓 / 親電子物質 / 活性イオウ / 心臓リモデリング / 細胞外ヌクレオチド / 心血管リモデリング / シグナル伝達 / Gタンパク質共役型受容体 / 高血圧 / アンジオテンシンII … More Except Principal Investigator ミトコンドリア / 心不全 / 心臓 / 創薬 / 硫黄 / 翻訳後修飾 / レドックス / 硫黄代謝 / 医療応用 / 代謝 / シグナル伝達 / Gタンパク質 / 超硫黄分子 / 活性イオウ / ミトコンドリア品質管理 / COVID-19 / 筋疾患 / 修復 / TRPチャネル / 品質管理 / ストレス抵抗性 / タンパク質間相互作用 / 死人リモデリング / レドックス制御 / 循環器内科学 / 心筋リモデリング / 酸化ストレス / スルフィレドキシン Less

Regulation of cardiac robustness and metabolic flexibility based on protein supersulfidationPrincipal Investigator
- Principal Investigator
  
  西村明幸
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Institute for Physiological Sciences
Novel signal regulation by G protein supersulfidation and its physiological role
- Principal Investigator
  
  西田基宏
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyushu University
Mechanism of mitochondrial quality defects focusing on the linkage with the cytoskeleton and its application to the treatment of chronic diseasesPrincipal Investigator
- Principal Investigator
  
  Nishimura Akiyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  National Institute for Physiological Sciences
  Kyushu University
Regulation of mitochondrial redox by sulfiredoxin in cardiac remodeling
- Principal Investigator
  
  Tsutsui Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
Elucidation of mechanism underlying dysregulation of mitochondrial quality control in the failing heart and its therapeutic strategy
- Principal Investigator
  
  Nishida Motohiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kyushu University
Adaptation to Environmental stress and quality control of myocardial mitochondria by reactive sulfur speciesPrincipal Investigator
- Principal Investigator
  
  Nishimura Akiyuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University
  National Institute for Physiological Sciences
Functional diversity and cardiac roles of purinergic P2Y6 receptorPrincipal Investigator
- Principal Investigator
  
  Nishimura Akiyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  National Institute for Physiological Sciences
心臓リモデリングにおけるプリン作動性受容体P2Y6の機能解析Principal Investigator
- Principal Investigator
  
  西村明幸
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  National Institute for Physiological Sciences

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book Patent

[Book] Japanese Scientists in Science Signaling 2016「シグナリングに載った日本人研究者」2017
- Author(s)
  西村明幸、西田基宏
- Total Pages
  2
- Publisher
  米国科学振興協会
- Data Source
  KAKENHI-PROJECT-15K18883
[Journal Article] Cardiac Remodeling: Novel Pathophysiological Mechanisms and Therapeutic Strategies2024
- Author(s)
  Nishida Motohiro、Mi Xinya、Ishii Yukina、Kato Yuri、Nishimura Akiyuki
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 4 Pages: 1-11
- DOI
  10.1093/jb/mvae031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] 2H-Thiopyran-2-thione sulfine, a compound for converting H2S to HSOH/H2S2 and increasing intracellular sulfane sulfur levels2024
- Author(s)
  Cui Qi、Shieh Meg、Pan Tony W.、Nishimura Akiyuki、Matsunaga Tetsuro、Kelly Shane S.、Xu Shi、Jung Minkyung、Ogata Seiryo、Morita Masanobu、Yoshitake Jun、Chen Xiaoyan、Robinson Jerome R.、Qian Wei-Jun、Nishida Motohiro、Akaike Takaaki、Xian Ming
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 2453-2453
- DOI
  10.1038/s41467-024-46652-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14333, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] Supersulfide prevents cigarette smoke extract-induced mitochondria hyperfission and cardiomyocyte early senescence by inhibiting Drp1-filamin complex formation2024
- Author(s)
  Nishimura Akiyuki、Zhou Liuchenzi、Kato Yuri、Mi Xinya、Ito Tomoya、Ibuki Yuko、Kanda Yasunari、Nishida Motohiro
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 2 Pages: 127-135
- DOI
  10.1016/j.jphs.2023.12.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] Pharmacological Activation of TRPC6 Channel Prevents Colitis Progression2024
- Author(s)
  Nishiyama Kazuhiro、Kato Yuri、Nishimura Akiyuki、Mi Xinya、Nagata Ryu、Mori Yasuo、Azuma Yasu-Taka、Nishida Motohiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 4 Pages: 2401-2401
- DOI
  10.3390/ijms25042401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06630, KAKENHI-PROJECT-22K19395, KAKENHI-PUBLICLY-22H04814, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] Echinochrome prevents sulfide catabolism-associated chronic heart failure after myocardial infarction in mice2023
- Author(s)
  Tang Xiaokang、Nishimura Akiyuki、Ariyoshi Kohei、Nishiyama Kazuhiro、Kato Yuri、Vasileva Elena A.、Mishchenko Natalia P.、Fedoreyev Sergey A.、Stonik Valentin A.、Kim Hyoung-Kyu、Han Jin、Kanda Yasunari、Umezawa Keitaro、Urano Yasuteru、Akaike Takaaki、Nishida Motohiro
- Journal Title
  
  Marine Drugs
  
  Volume: 21 Issue: 1 Pages: 52-52
- DOI
  10.3390/md21010052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] Supersulfide catalysis for nitric oxide and aldehyde metabolism2023
- Author(s)
  Kasamatsu Shingo、Nishimura Akira、Alam Md. Morshedul、Morita Masanobu、Shimoda Kakeru、Matsunaga Tetsuro、Jung Minkyung、Ogata Seiryo、Barayeu Uladzimir、Ida Tomoaki、Nishida Motohiro、Nishimura Akiyuki、Motohashi Hozumi、Akaike Takaaki
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 33 Pages: 1-11
- DOI
  10.1126/sciadv.adg8631
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14333, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06148, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-23K06386, KAKENHI-PROJECT-21K05504, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-23K24035
[Journal Article] Knockout of Purinergic P2Y6 Receptor Fails to Improve Liver Injury and Inflammation in Non-Alcoholic Steatohepatitis2023
- Author(s)
  Nishiyama K, Ariyoshi K, Nishimura A, Kato Y, Mi X, Kurose H, Kim SG, Nishida M.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3800-3800
- DOI
  10.3390/ijms24043800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06630, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation2022
- Author(s)
  Tokuyama T、Uosaki H、Sugiura A、Nishitai G、Takeda K、Nagashima S、Shiiba I、Ito N、Amo T、Mohri S、Nishimura A、Nishida M、Konno A、Hirai H、Ishido S、Yoshizawa T、Shindo T、Takada S、Kinugawa S、Inatome R、Yanagi S
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 7 Pages: 104582-104582
- DOI
  10.1016/j.isci.2022.104582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07878, KAKENHI-PROJECT-21K06844, KAKENHI-PROJECT-22K19754, KAKENHI-PROJECT-22K15399, KAKENHI-PROJECT-19KK0219, KAKENHI-PLANNED-21H05269, KAKENHI-PUBLICLY-22H05574, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20H03454, KAKENHI-PROJECT-21H03360, KAKENHI-PROJECT-19K06899, KAKENHI-PROJECT-19K22791, KAKENHI-PROJECT-23K24334, KAKENHI-PROJECT-22K06454
[Journal Article] Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress2022
- Author(s)
  Akiyama Masahiro、Unoki Takamitsu、Aoki Hanako、Nishimura Akiyuki、Shinkai Yasuhiro、Warabi Eiji、Nishiyama Kazuhiro、Furumoto Yuka、Anzai Naohiko、Akaike Takaaki、Nishida Motohiro、Kumagai Yoshito
- Journal Title
  
  Redox Biology
  
  Volume: 57 Pages: 102514-102514
- DOI
  10.1016/j.redox.2022.102514
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06572, KAKENHI-PROJECT-22K19395, KAKENHI-PROJECT-22K19397, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PUBLICLY-22H05555, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20H04340, KAKENHI-PROJECT-21H03065, KAKENHI-PUBLICLY-22H04799, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277
[Journal Article] Inhibition of transient receptor potential cation channel?6 promotes capillary arterialization during post‐ischaemic blood flow recovery2022
- Author(s)
  Numaga‐Tomita Takuro、Shimauchi Tsukasa、Kato Yuri、Nishiyama Kazuhiro、Nishimura Akiyuki、Sakata Kosuke、Inada Hiroyuki、Kita Satomi、Iwamoto Takahiro、Nabekura Junichi、Birnbaumer Lutz、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 180 Issue: 1 Pages: 94-110
- DOI
  10.1111/bph.15942
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19395, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-20K07302, KAKENHI-PROJECT-23K24035
[Journal Article] Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression2022
- Author(s)
  Nishiyama Kazuhiro、Nishimura Akiyuki、Shimoda Kakeru、Tanaka Tomohiro、Kato Yuri、Shibata Takahiro、Tanaka Hiroshi、Kurose Hitoshi、Azuma Yasu-Taka、Ihara Hideshi、Kumagai Yoshito、Akaike Takaaki、Eaton Philip、Uchida Koji、Nishida Motohiro
- Journal Title
  
  Science Signaling
  
  Volume: 15 Issue: 716 Pages: 716-716
- DOI
  10.1126/scisignal.abj0644
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K21496, KAKENHI-PROJECT-20K16008, KAKENHI-PLANNED-21H05263, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19J20086, KAKENHI-PROJECT-22K06646, KAKENHI-ORGANIZER-21H05258, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-22H00356
[Journal Article] Cardiac robustness regulated by reactive sulfur species2022
- Author(s)
  Nishimura Akiyuki、Tanaka Tomohiro、Kato Yuri、Nishiyama Kazuhiro、Nishida Motohiro
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 1 Pages: 1-6
- DOI
  10.3164/jcbn.21-84
- NAID
  130008139104
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05269
[Journal Article] A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia.2022
- Author(s)
  Shimauchi T, Numaga-Tomita T, Kato Y, Morimoto H, Sakata K, Matsukane R, Nishimura A, Nishiyama K, Shibuta A, Horiuchi Y, Kurose H, Kim SG, Urano Y, Ohshima T, Nishida M.
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 13 Pages: 2041-2041
- DOI
  10.3390/cells11132041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06646, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05208, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-21H02607, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-23K24035
[Journal Article] Drug repurposing for the treatment of COVID-192022
- Author(s)
  Kato Y, Nishiyama K, Nishimura A, Noda T, Okabe K, Kusakabe T, Kanda Y, Nishida M.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 149 Issue: 3 Pages: 108-114
- DOI
  10.1016/j.jphs.2022.04.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19394, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-21H02634, KAKENHI-PROJECT-23K24035
[Journal Article] 心筋の頑健性と超硫黄分子代謝2021
- Author(s)
  西田基宏、西村明幸、田中智弘、加藤百合、西山和宏
- Journal Title
  
  生化学
  
  Volume: 93(5) Pages: 1-6
- Data Source
  KAKENHI-PLANNED-21H05269
[Journal Article] Deletion of TRPC3 or TRPC6 Fails to Attenuate the Formation of Inflammation and Fibrosis in Non-alcoholic Steatohepatitis2021
- Author(s)
  Nishiyama Kazuhiro、Toyama Chiemi、Kato Yuri、Tanaka Tomohiro、Nishimura Akiyuki、Nagata Ryu、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 3 Pages: 431-436
- DOI
  10.1248/bpb.b20-00903
- NAID
  130007993444
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PUBLICLY-20H05512, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19K16363
[Journal Article] Clomipramine suppresses ACE2-mediated SARS-CoV-2 entry2021
- Author(s)
  Kato Yuri、Yamada Shigeru、Nishiyama Kazuhiro、Satsuka Ayano、Re Suyong、Tomokiyo Daiki、Lee Jae Man、Tanaka Tomohiro、Nishimura Akiyuki、Yonemitsu Kenzo、Asakura Hiroshi、Ibuki Yuko、Imai Yumiko、Kamiya Noriho、Mizuguchi Kenji、Kusakabe Takahiro、Kanda Yasunari、Nishida Motohiro
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2021.03.13.435221
- Open Access
- Data Source
  KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383
[Journal Article] GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway2021
- Author(s)
  Ishikita Akihito、Matsushima Shouji、Ikeda Soichiro、Okabe Kosuke、Nishimura Ryohei、Tadokoro Tomonori、Enzan Nobuyuki、Yamamoto Taishi、Sada Masashi、Tsutsui Yoshitomo、Miyake Ryo、Ikeda Masataka、Ide Tomomi、Kinugawa Shintaro、Tsutsui Hiroyuki
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 12 Pages: 103517-103517
- DOI
  10.1016/j.isci.2021.103517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22902, KAKENHI-PROJECT-19H03655, KAKENHI-PROJECT-20K08426, KAKENHI-PROJECT-21K08082, KAKENHI-PROJECT-21K19485, KAKENHI-PROJECT-21K16026, KAKENHI-PROJECT-21K16090
[Journal Article] 心筋の頑健性と超硫黄分子代謝2021
- Author(s)
  西田基宏、西村明幸、田中智弘、加藤百合、西山和宏
- Journal Title
  
  生化学
  
  Volume: 93(5) Pages: 1-6
- Data Source
  KAKENHI-PROJECT-19H03383
[Journal Article] Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity2020
- Author(s)
  Nishida Motohiro、Tanaka Tomohiro、Mangmool Supachoke、Nishiyama Kazuhiro、Nishimura Akiyuki
- Journal Title
  
  Journal of Lipid and Atherosclerosis
  
  Volume: 9 Issue: 1 Pages: 124-124
- DOI
  10.12997/jla.2020.9.1.124
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PUBLICLY-20H05512, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC3-based protein signaling complex as a therapeutic target of myocardial atrophy2020
- Author(s)
  Nishiyama K, Tanaka T, Nishimura A, Nishida M
- Journal Title
  
  Current molecular pharmacology
  
  Volume: - Issue: 2 Pages: 123-131
- DOI
  10.2174/1874467213666200407090121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PROJECT-19H03383, KAKENHI-PUBLICLY-20H05512
[Journal Article] Mitochondrial dynamics in exercise physiology2020
- Author(s)
  Tanaka T, Nishimura A, Nishiyama K, Goto T, Numaga-Tomita T, Nishida M
- Journal Title
  
  Pflugers Arch.
  
  Volume: 472 Pages: 137-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07085
[Journal Article] RAA系と細胞老化2020
- Author(s)
  西田基宏、加藤百合、田中智弘、西山和宏、西村明幸
- Journal Title
  
  日本臨床（増刊）　高血圧学（上）
  
  Volume: 78 (6) Pages: 308-314
- Data Source
  KAKENHI-PROJECT-19H03383
[Journal Article] Gタンパク質共役型受容体2020
- Author(s)
  西田基宏、西山和宏、加藤百合、田中智弘、西村明幸
- Journal Title
  
  実験医学
  
  Volume: 38, No. 10 Pages: 144-148
- Data Source
  KAKENHI-PROJECT-19H03383
[Journal Article] Modulation of P2Y6R expression exacerbates pressure overload-induced cardiac remodeling in mice2020
- Author(s)
  Shimoda Kakeru、Nishimura Akiyuki、Sunggip Caroline、Ito Tomoya、Nishiyama Kazuhiro、Kato Yuri、Tanaka Tomohiro、Tozaki-Saitoh Hidetoshi、Tsuda Makoto、Nishida Motohiro
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13926-13926
- DOI
  10.1038/s41598-020-70956-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19J20086, KAKENHI-PROJECT-19K22443
[Journal Article] ミトコンドリア異常は心不全の原因か2020
- Author(s)
  西田基宏、加藤百合、田中智弘、西山和宏、西村明幸
- Journal Title
  
  循環器内科
  
  Volume: 87(5) Pages: 579-584
- Data Source
  KAKENHI-PROJECT-19H03383
[Journal Article] Ibudilast attenuates doxorubicin‐induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes2019
- Author(s)
  Nishiyama Kazuhiro、Numaga‐Tomita Takuro、Fujimoto Yasuyuki、Tanaka Tomohiro、Toyama Chiemi、Nishimura Akiyuki、Yamashita Tomohiro、Matsunaga Naoya、Koyanagi Satoru、Azuma Yasu‐Taka、Ibuki Yuko、Uchida Koji、Ohdo Shigehiro、Nishida Motohiro
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 176 Issue: 18 Pages: 3723-3738
- DOI
  10.1111/bph.14777
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K16363, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-18K14921, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-17H06170
[Journal Article] TRPC channels in exercise-mimetic therapy2019
- Author(s)
  Numaga-Tomita T, Oda S, Nishiyama K, Tanaka T, Nishimura A, Nishida M
- Journal Title
  
  Pflugers Arch.
  
  Volume: 471 Pages: 507-517
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085
[Journal Article] TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential‐dependent coupling with PTEN2019
- Author(s)
  Numaga‐Tomita Takuro、Shimauchi Tsukasa、Oda Sayaka、Tanaka Tomohiro、Nishiyama Kazuhiro、Nishimura Akiyuki、Birnbaumer Lutz、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 9 Pages: 9785-9796
- DOI
  10.1096/fj.201802811r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K07116, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J14538, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19H03383, KAKENHI-ORGANIZER-15H05935
[Journal Article] ミトコンドリア品質管理と心筋老化制御2019
- Author(s)
  西田基宏、田中智弘、西村明幸
- Journal Title
  
  実験医学
  
  Volume: 37(12) Pages: 1959-1965
- Data Source
  KAKENHI-PROJECT-19H03383
[Journal Article] Mitochondrial dynamics in exercise physiology.2019
- Author(s)
  Tanaka T, Nishimura A, Nishiyama K, Goto T, Numaga-Tomita T, Nishida M.
- Journal Title
  
  Pflugers Archiv European Journal of Physiology
  
  Volume: 印刷中 Issue: 2 Pages: 1-17
- DOI
  10.1007/s00424-019-02258-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-18H05293, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy2019
- Author(s)
  Sudi Suhaini Binti、Tanaka Tomohiro、Oda Sayaka、Nishiyama Kazuhiro、Nishimura Akiyuki、Sunggip Caroline、Mangmool Supachoke、Numaga-Tomita Takuro、Nishida Motohiro
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 9785-9785
- DOI
  10.1038/s41598-019-46252-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-19K16363, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J14538, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19H03383
[Journal Article] 酸化／還元ストレスと心臓2019
- Author(s)
  西田基宏、西山和宏、田中智弘、西村明幸
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 72(1) Pages: 29-35
- Data Source
  KAKENHI-PROJECT-19H03383
[Journal Article] Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload2019
- Author(s)
  Nishimura Akiyuki、Shimoda Kakeru、Tanaka Tomohiro、Toyama Takashi、Nishiyama Kazuhiro、Shinkai Yasuhiro、Numaga-Tomita Takuro、Yamazaki Daiju、Kanda Yasunari、Akaike Takaaki、Kumagai Yoshito、Nishida Motohiro
- Journal Title
  
  Science Signaling
  
  Volume: 12 Issue: 587
- DOI
  10.1126/scisignal.aaw1920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K16363, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J20086, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC channels in exercise-mimetic therapy.2018
- Author(s)
  Numaga-Tomita T, Oda S, Nishiyama K, Tanaka T, Nishimura A, Nishida M.
- Journal Title
  
  Pflugers Archiv European Journal of Physiology
  
  Volume: 471 Issue: 3 Pages: 507-517
- DOI
  10.1007/s00424-018-2211-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H05092, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-19J14538, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383
[Journal Article] Prolonged stimulation of β2-adrenergic receptor with β2-agonists impairs insulin actions in H9c2 cells2018
- Author(s)
  Parichatikanond Warisara、Nishimura Akiyuki、Nishida Motohiro、Mangmool Supachoke
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 138 Issue: 3 Pages: 184-191
- DOI
  10.1016/j.jphs.2018.09.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293
[Journal Article] TRPC5-eNOS axis negatively regulates ATP-induced cardiomyocyte hypertrophy2018
- Author(s)
  Sunggip C., Shimoda K., Oda S., Tanaka T., Nishiyama K., Mangmool S., Nishimura A., Numaga-Tomita T. and Nishida M.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15464
[Journal Article] TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy.2018
- Author(s)
  Sunggip C, Shimoda K, Oda S, Tanaka T, Nishiyama K, Mangmool S, Nishimura A, Numaga-Tomita T and Nishida M
- Journal Title
  
  Front. Pharmacol.
  
  Volume: 9 Pages: 523-523
- DOI
  10.3389/fphar.2018.00523
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15585, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293, KAKENHI-ORGANIZER-15H05935
[Journal Article] Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence.2018
- Author(s)
  Nishimura A, Shimauchi T, Tanaka T, Shimoda K, Toyama T, Kitajima N, Ishikawa T, Shindo N, Numaga-Tomita T, Yasuda S, Sato Y, Kuwahara K, Kumagai Y, Akaike T, Ide T, Ojida A, Mori Y, Nishida M.
- Journal Title
  
  Sci Signal
  
  Volume: 11 Issue: 556 Pages: 5185-5195
- DOI
  10.1126/scisignal.aat5185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-17H04174, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15483, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293
[Journal Article] Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases2017
- Author(s)
  Nishimura Akiyuki、Sunggip Caroline、Oda Sayaka、Numaga-Tomita Takuro、Tsuda Makoto、Nishida Motohiro
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 180 Pages: 113-128
- DOI
  10.1016/j.pharmthera.2017.06.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics2017
- Author(s)
  Akaike Takaaki、、、Nishida Motohiro（4）、、、、、、Fujii Shigemoto（20）、、、Motohashi Hozumi（26）
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1177-1177
- DOI
  10.1038/s41467-017-01311-y
- NAID
  120007134656
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K15408, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K17583, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26110003, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K13089, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-15K20876, KAKENHI-PLANNED-26116005, KAKENHI-PROJECT-16H05092
[Journal Article] TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy2017
- Author(s)
  Shimauchi Tsukasa、Numaga-Tomita Takuro、Ito Tomoya、Nishimura Akiyuki、Matsukane Ryosuke、Oda Sayaka、Hoka Sumio、Ide Tomomi、Koitabashi Norimichi、Uchida Koji、Sumimoto Hideki、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  The JCI insight
  
  Volume: 2 Issue: 15 Pages: 93358-93358
- DOI
  10.1172/jci.insight.93358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15585, KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111004, KAKENHI-PLANNED-26111009, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] Purinergic signaling in cardiovascular system2017
- Author(s)
  Nishimura A, Nishida M.
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 149 Issue: 2 Pages: 84-90
- DOI
  10.1254/fpj.149.84
- NAID
  130005306336
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18883
[Journal Article] TRPC3 Channels in Cardiac Fibrosis2017
- Author(s)
  Numaga-Tomita Takuro、Oda Sayaka、Shimauchi Tsukasa、Nishimura Akiyuki、Mangmool Supachoke、Nishida Motohiro
- Journal Title
  
  Frontiers in Cardiovasc Med
  
  Volume: 4 Pages: 56-56
- DOI
  10.3389/fcvm.2017.00056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] Stimulation of Adenosine A2B Receptor Inhibits Endothelin-1-Induced Cardiac Fibroblast Proliferation and α-Smooth Muscle Actin Synthesis Through the cAMP/Epac/PI3K/Akt-Signaling Pathway2017
- Author(s)
  Phosri Sarawuth、Arieyawong Ajaree、Bunrukchai Kwanchai、Parichatikanond Warisara、Nishimura Akiyuki、Nishida Motohiro、Mangmool Supachoke
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 8 Pages: 428-428
- DOI
  10.3389/fphar.2017.00428
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice2017
- Author(s)
  Oda Sayaka、Numaga-Tomita Takuro、Kitajima Naoyuki、Toyama Takashi、Harada Eri、Shimauchi Tsukasa、Nishimura Akiyuki、Ishikawa Tatsuya、Kumagai Yoshito、Birnbaumer Lutz、Nishida Motohiro
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 7511-7511
- DOI
  10.1038/s41598-017-07903-4
- NAID
  120007128849
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15488, KAKENHI-PROJECT-17K15585, KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells2017
- Author(s)
  Nishida M, Nishimura A, Matsunaga T, Motohashi H, Kasamatsu S, Akaike T.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 印刷中 Pages: 30033-3
- DOI
  10.1016/j.freeradbiomed.2017.01.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K17583, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855
[Journal Article] Purinergic P2Y6 receptors: a new therapeutic target of age-dependent hypertension2017
- Author(s)
  Sunggip C, Nishimura A, Shimoda K, Numaga-Tomita T, Tsuda M, and Nishida M. M
- Journal Title
  
  Pharmacological Research
  
  Volume: 120 Pages: 51-59
- DOI
  10.1016/j.phrs.2017.03.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] The purinergic P2Y6 receptor heterodimerizes with the angiotensin AT1 receptor to promote angiotensin II-induced hypertension2016
- Author(s)
  A. Nishimura, C. Sunggip, H. Tozaki-Saitoh, T. Shimauchi, T. Numaga-Tomita, K. Hirano, T. Ide, J-M. Boeynaems, H. Kurose, M. Tsuda, B. Robaye, K. Inoue and M. Nishida
- Journal Title
  
  Science Signaling
  
  Volume: Jan 19;9(411) Issue: 411
- DOI
  10.1126/scisignal.aac9187
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25293018, KAKENHI-PROJECT-26670144, KAKENHI-PLANNED-25117013, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25253011
[Journal Article] TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.2016
- Author(s)
  Numaga-Tomita T., Kitajima N., Kuroda T., Nishimura A., Miyano K., Yasuda S., Kuwahara K., Sato Y., Ide T., Birnbaumer L., Sumimoto H., Mori Y. and Nishida M.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 39383-39383
- DOI
  10.1038/srep39383
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111004, KAKENHI-PLANNED-26111009, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-26293187, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K15442
[Journal Article] TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling.2016
- Author(s)
  Kitajima N., Numaga-Tomita T., Watanabe M., Kuroda T., Nishimura A., Miyano K., Yasuda S., Kuwahara K., Sato Y., Ide T., Birnbaumer L., Sumimoto H., Mori Y. and Nishida M
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 37701-37701
- DOI
  10.1038/srep37001
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111004, KAKENHI-PLANNED-26111009, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-26293187, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K15442
[Journal Article] Light-dependent activation of G proteins by two isoforms of chicken melanopsins.2015
- Author(s)
  Masaki Torii, Daisuke Kojima, Akiyuki Nishimura Hiroshi Itoh, Yoshitaka Fukada
- Journal Title
  
  Photochem. Photobiol. Sci.
  
  Volume: 14 Issue: 11 Pages: 1991-1997
- DOI
  10.1039/c5pp00153f
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07144, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-25293013, KAKENHI-PROJECT-24227001
[Journal Article] Divergent Roles of CAAX Motif-signaled Posttranslational Modifications in the Regulation and Subcellular Localization of Ral GTPases2015
- Author(s)
  LR Gentry, A. Nishimura, A.D. Cox, T.D. Martin, D. Tsygankov, M. Nishida, T.C. Elston and C.J. Der
- Journal Title
  
  J Biol Chem.
  
  Volume: 290(37) Issue: 37 Pages: 22851-22861
- DOI
  10.1074/jbc.m115.656710
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25293018, KAKENHI-PLANNED-26111011
[Patent] ＴＲＰＣ３／６／７チャネル活性化による強心作用を介した心不全治療2023
- Inventor(s)
  西田基宏、西山和宏、西村明幸、永田龍、森泰生、他
- Industrial Property Rights Holder
  西田基宏、西山和宏、西村明幸、永田龍、森泰生、他
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PLANNED-21H05269
[Patent] Drp1-Filamin complex formation inhibitors2020
- Inventor(s)
  西田基宏、西村明幸、王子田彰夫、進藤直哉
- Industrial Property Rights Holder
  西田基宏、西村明幸、王子田彰夫、進藤直哉
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03383
[Patent] Drp1-Filamin複合体形成阻害剤及び新規化合物2019
- Inventor(s)
  西田基宏、西村明幸、王子田彰夫、進藤直哉
- Industrial Property Rights Holder
  西田基宏、西村明幸、王子田彰夫、進藤直哉
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-103034
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03383
[Presentation] Drp1タンパク質のシステイン修飾を介したミトコンドリア過剰分裂を伴う心筋老化2023
- Author(s)
  西村明幸、湯肖康、加藤百合、熊谷嘉人、赤池孝章、西田基宏
- Organizer
  第97回日本薬理学会年会（神戸）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 超硫黄分子イメージングから解き明かす心臓恒常性の維持・変容機構における硫黄代謝の役割2023
- Author(s)
  西村明幸、Tang Xiaokang、立花洸季、西田基宏
- Organizer
  第96回日本生化学会　（福岡）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Drp1-Filamin 複合体形成阻害による肝脂肪滴の蓄積抑制2023
- Author(s)
  有吉航平、西山和宏、立花洸季、田中智弘、加藤百合、西村明幸、西田基宏
- Organizer
  第96回生化学会大会（福岡)
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 心臓の虚血耐性における硫黄代謝の役割解明2023
- Author(s)
  西村明幸、Tang Xiaokang、西田基宏
- Organizer
  名大－生理研合同シンポジウム（岡崎）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 超硫黄分子の細胞内代謝に着目した心不全治療戦略2023
- Author(s)
  西田基宏、西村明幸、Tang Xiaokang、加藤百合
- Organizer
  第76回日本酸化ストレス学会学術集会（神戸）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Supersulfide production via CARS contributes to ischemic stress resistance of the heart2023
- Author(s)
  Tang Xiaokang、下田翔、西村明幸、守田匡伸、赤池孝章、西田基宏
- Organizer
  生理研心血管研究会2023（岡崎）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Supersulfide-based bulking of dynamin-related protein 1 prevents ischemic sulfide catabolism and heart failure in mice2023
- Author(s)
  Tang Xiaokang、西村明幸、西田基宏
- Organizer
  第22回次世代を担う若手ファーマ・バイオフォーラム2023（福岡）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 肝臓の脂肪蓄積におけるDrp1-filamin Aタンパク質複合体形成の関与2023
- Author(s)
  有吉航平、西山和宏、田中智弘、立花洸季、加藤百合、西村明幸、西田基宏
- Organizer
  第76回薬理学会西南部会（沖縄)
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] ミトコンドリアダイナミクスを標的とする糖代謝改善2023
- Author(s)
  加藤百合、有吉航平、島内司、西村明幸、Mi Xinya、立花洸季、西山和宏、田中智弘、川西英治、王子田彰夫、西田基宏
- Organizer
  第96回日本生化学会（福岡）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Supersulfide production via CARS2 contributes to ischemic stress resistance of the heart2023
- Author(s)
  Tang Xiaokang、下田翔、西村明幸、守田匡伸、赤池孝章、西田基宏
- Organizer
  第96回日本生化学会（福岡）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Drp1-Filamin 相互作用の阻害はグルコース代謝を改善する2023
- Author(s)
  加藤百合、有吉航平、島内司、進藤直哉、西村明幸、Mi Xinya、川西英治、王子田彰夫、西田基宏
- Organizer
  生理研心血管研究会2023（岡崎）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 硫黄代謝に基づく心筋虚血耐性機構の解明と心不全治療への応用2023
- Author(s)
  西村明幸、Tang Xiaokang、加藤百合、西田基宏
- Organizer
  第74回日本薬理学会北部会（秋田）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Drp1グルタチオン化による心筋虚血耐性機構の解析2023
- Author(s)
  西村明幸、Tang Xiaokang、西田基宏
- Organizer
  生理研心血管研究会2023（岡崎）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 肝臓の脂肪蓄積におけるDrp1-filaminタンパク質間相互作用の関与2023
- Author(s)
  有吉航平、西山和宏、立花洸季、田中智弘、加藤百合、西村明幸、西田基宏
- Organizer
  第40回日本薬学会九州山口支部大会（福岡)
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 新型コロナウイルス感染症に対する新規治療標的の提案とその薬理学的応用2023
- Author(s)
  石井志奈、加藤百合、西山和宏、友清大樹、田中智弘、西村明幸、西田基宏
- Organizer
  第96回日本生化学会（福岡）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 超硫黄分子産生酵素CARS2による心筋虚血耐性機構2023
- Author(s)
  Tang Xiaokang、下田翔、西村明幸、西山和宏、加藤百合、赤池孝章、守田匡伸、西田基宏
- Organizer
  第74回日本薬理学会北部会（秋田）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 硫黄代謝による心臓恒常性制御と環境親電子物質によってもたらされる破綻2023
- Author(s)
  西村明幸、下田翔、Tang Xiaokang、西田基宏
- Organizer
  第50回日本毒性学会学術年会（横浜）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 心不全モデルマウスにおける超硫黄化タンパク質の解析2023
- Author(s)
  立花洸季、西村明幸、西田基宏
- Organizer
  生理研心血管研究会2023（岡崎）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 高血糖時の肝脂肪滴蓄積におけるDrp1-filamin A複合体形成の関与2023
- Author(s)
  有吉航平、西山和宏、田中智弘、立花洸季、加藤百合、西村明幸、西田基宏
- Organizer
  第22回次世代を担う若手ファーマ・バイオフォーラム2023（福岡）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Gタンパク質の超硫黄修飾に着目した脂質－レドックス間相互作用とその意義2023
- Author(s)
  西田基宏、西村明幸
- Organizer
  第97回日本薬理学会年会（神戸）
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Sulfide metabolism has principal roles in ischemic resistance of the heart2023
- Author(s)
  Akiyuki Nishimura and Motohiro Nishida
- Organizer
  Society for Heart and Vascular Metabolism (Gratz)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 心臓の虚血耐性における活性硫黄分子の役割2022
- Author(s)
  下田翔、西村明幸、西山和宏、加藤百合、赤池孝章、守田匡伸、西田基宏
- Organizer
  薬学会薬理系部会　次世代を担う若手のための創薬・医療薬理シンポジウム
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 超硫黄分子による心筋の虚血耐性機構の解析2022
- Author(s)
  西村明幸、下田翔、西山和宏、加藤百合、西田基宏
- Organizer
  第75回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Mechanism of cardiomyocytes aging due to cigarette sidestream smoke2022
- Author(s)
  Xiaokang Tang, Akiyuki Nishimura, Kazuhiro Nishiyama, Yuri Kato, Yuko Ibuki, Takaaki Akaike, Yoshito Kumagai, Motohiro Nishida
- Organizer
  フォーラム2022：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Cold plasma-irradiated cysteine attenuates aberrant sulfide metabolism induced by ischemia2022
- Author(s)
  Kakeru Shimoda, Akiyuki Nishimura, Tomoaki Ida, Shota Sasaki, Tomohiro Tanaka, Toshiro Kaneko, Takaaki Akaike, Motohiro Nishida
- Organizer
  The 12th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] GSSG rescues Drp1 mediated mitochondrial hyperfission and cardiac vulnerability by electrophilic glutathionylation at Cys6242022
- Author(s)
  Xiaokang Tang, Akiyuki Nishimura, Motohiro Nishida
- Organizer
  レドックス R&D 戦略委員会第2回若手シンポジウム
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] スルフォラファンによる GPCR 内在化機構の発見2022
- Author(s)
  西山和宏、西村明幸、下田翔、加藤百合、柴田貴広、熊谷嘉人、赤池孝章、内田浩二、西田基宏
- Organizer
  フォーラム2022：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 硫黄代謝によるミトコンドリア品質制御を介した心筋頑健性機構の解析2022
- Author(s)
  西村明幸、湯肖康、下田翔、加藤百合、西山和宏、西田基宏
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Environmental stress-induced aberrant mitochondrial fission underlies cardiac vulnerability to mechanical load through Drp1 depolysulfidation2022
- Author(s)
  Akiyuki Nishimura, Kakeru Shimoda, Xiaokang Tang, Kazuhiro Nishiyama, Yuri Kato, Yuko Ibuki, Takaaki Akaike, Yoshito Kumagai, Motohiro Nishida
- Organizer
  The 4th International Conference on Persulfide and Sulfur Metabolism in Biology and Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Redox-dependent alternative internalization (REDAI) of GPCRs2022
- Author(s)
  Kazuhiro Nishiyama, Akiyuki Nishimura, Kakeru Shimoda, Yuri Kato, Yoshito Kumagai, Takaaki Akaike, Philip Eaton, Koji Uchida, Motohiro Nishida
- Organizer
  The 12th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Echinochrome prevents sulfide catabolism-associated chronic heart failure after myocardial infarction in mice2022
- Author(s)
  Xiaokang Tang, Akiyuki Nishimura, Kazuhiro Nishiyama, Yuri Kato, Elena A Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Hyoung, Kyu Kim, Jin Han, and Motohiro Nishida
- Organizer
  The 12th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 超硫黄分子による心筋の虚血耐性機構2022
- Author(s)
  西村明幸、下田翔、田中智弘、西山和宏、加藤百合、井田智章、赤池孝章、西田基宏
- Organizer
  第21回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] Echinochrome enhances myocardial stress resistance by preserving reactive sulfur species2022
- Author(s)
  Xiaokang Tang, Akiyuki Nishimura, Kazuhiro Nishiyama, Yuri Kato, Elena A Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Hyoung, Kyu Kim, Jin Han, and Motohiro Nishida
- Organizer
  薬学会薬理系部会　生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] GSSG rescues Drp1 mediated mitochondrial hyperfission and cardiac vulnerability by electrophilic glutathionylation at Cys6242022
- Author(s)
  Xiaokang Tang, Akiyuki Nishimura, Motohiro Nishida
- Organizer
  第21回次世代を担う若手のためのファーマ・バイオフォーラム 2022
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] システイン修飾を介したGPCRの内在化機構の解明2022
- Author(s)
  西山和宏、西村明幸、加藤百合、下田翔、西田基宏
- Organizer
  第51回日本心脈管作動物質学会
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 超硫黄分子生成酵素CARS2の心筋虚血耐性における役割2022
- Author(s)
  下田翔、西村明幸、西山和宏、加藤百合、守田匡伸、赤池孝章、西田基宏
- Organizer
  レドックスR&D戦略委員会第2回若手シンポジウム
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] Pathology-dependent Aberrant Interaction between Mitochondria and Actin Cytoskeleton Causes Cardiac Fragility2021
- Author(s)
  Akiyuki Nishimura, Kakeru Shimoda, Tomohiro Tanaka, Kazuhiro Nishiyama, Motohiro Nishida
- Organizer
  第85回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] 脂質作動性TRPCチャネルタンパク質の機能多様性に着目した創薬2021
- Author(s)
  西田基宏、小田紗矢香、加藤百合、西村明幸、西山和宏
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PLANNED-21H05269
[Presentation] 新規硬さセンサーGPCRsの同定と筋組織における役割の解明2021
- Author(s)
  西村明幸、下田翔、田中智弘、西山和宏、加藤百合、西田基宏
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] タバコ副流煙による心筋早期老化の誘導機構2021
- Author(s)
  西村明幸、後藤拓実、西山和宏、加藤百合、田中智弘、伊吹裕子、西田基宏
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] Mitochondrial quality control in cardiac homeostasis and disease2021
- Author(s)
  Akiyuki Nishimura, Kakeru Shimoda, Tomohiro Tanaka, Kazuhiro Nishiyama, Motohiro Nishida
- Organizer
  第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] 脂質作動性TRPCチャネルタンパク質の機能多様性に着目した創薬2021
- Author(s)
  西田基宏、小田紗矢香、加藤百合、西村明幸、西山和宏　「」　10月9日（WEB開催）シンポジウム講演
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19H03383
[Presentation] 超硫黄分子による心臓頑健性制御2021
- Author(s)
  西村明幸、下田翔、田中智弘、西山和宏、加藤百合、西田基宏
- Organizer
  生理研研究会－比較統合生理学的観点からの循環生理の解析－
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] ミトコンドリア品質による心筋リモデリング機構2021
- Author(s)
  西村明幸
- Organizer
  CVMW2020　心血管代謝週間
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] Myocardial atrophy regulated by the formation of TRPC3 protein complex2020
- Author(s)
  西田基宏、田中智弘、西山和宏、西村明幸
- Organizer
  第93回日本薬理学会年会（誌上開催）シンポジウム講演
- Data Source
  KAKENHI-PROJECT-19H03383
[Presentation] 抗がん剤投与による心筋萎縮におけるTRPC3-Nox2複合体形成の役割2020
- Author(s)
  西田基宏、田中智弘、小田紗矢香、西村明幸、西山和宏
- Organizer
  第49回日本心脈管作動物質学会（久留米）シンポジウム講演
- Data Source
  KAKENHI-PROJECT-19H03383
[Presentation] ミトコンドリア分裂促進因子Drp1の脱イオウ化を介した心筋脆弱性機構2019
- Author(s)
  西村明幸、田中智弘、下田翔、西山和宏、西田基宏
- Organizer
  第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] pathology-dependent aberrant interaction between mitochondria and actin cytoskeleton causes cardiac fragility.2019
- Author(s)
  Akiyuki Nishimura, Kakeru Shimoda, Tomohiro Tanaka, Kazuhiro Nishiyama, Motohiro Nishida
- Organizer
  第50回生理研国際シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07085
[Presentation] Drp1-Filamin A複合体によるミトコンドリア過剰分裂を介した心筋細胞の早期老化機構2018
- Author(s)
  西村明幸、田中智弘、下田翔、冨田拓郎、西田基宏
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] メチル水銀による心毒性と活性イオウ分子種による制御2018
- Author(s)
  西村明幸、西山和宏、田中智弘、冨田拓郎、西田基宏
- Organizer
  メタルバイオサイエンス研究会2018
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] 親電子物質と活性イオウによる心筋ミトコンドリアの品質管理2018
- Author(s)
  西村明幸、田中智弘、冨田拓郎、西田基宏
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] 活性イオウによるミトコンドリア品質管理2018
- Author(s)
  西村明幸、田中智弘、西山和宏、西田基宏
- Organizer
  日本薬学会　第138年会
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] ミトコンドリア－アクチン細胞骨格連携による心筋細胞の早期老化機構2018
- Author(s)
  西村明幸、島内司、田中智弘、下田翔、冨田　拓郎、西田基宏
- Organizer
  心血管膜輸送研究会2018
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] メチル水銀による心毒性と活性イオウ分子種による制御2018
- Author(s)
  西村明幸、田中智弘、冨田拓郎、西田基宏
- Organizer
  日本薬学会　第138年会
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] Age-dependent dimer formation of AT1R and P2Y6R promotes angiotensin II-induced hypertension2018
- Author(s)
  Akiyuki Nishimura, Caroline Sunggip, Takuro Numaga-Tomita, Motohiro Nishida
- Organizer
  FAOPS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] メチル水銀による心毒性と活性イオウ分子種による制御2018
- Author(s)
  西村明幸、田中智弘、冨田拓郎、西田基宏
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] Drp1-Filamin A相互作用による心筋ミトコンドリアの品質管理機構2018
- Author(s)
  西村明幸、島内司、田中智弘、冨田拓郎、西田基宏
- Organizer
  第71回日本酸化ストレス学会／第18回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] 活性イオウによるミトコンドリア品質管理2018
- Author(s)
  西村明幸、田中智弘、西山和宏、西田基宏
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] 加齢に伴うAT1R-P2Y6R複合体形成によるアンジオテンシンII誘発性高血圧の制御2017
- Author(s)
  西村明幸、Caroline Sunggip、冨田拓郎、西田基宏
- Organizer
  Conbio2017
- Data Source
  KAKENHI-PROJECT-17K15464
[Presentation] Drp1-細胞骨格の相互作用による心筋ミトコンドリアの品質管理2016
- Author(s)
  西村明幸、島内司、石川達也、冨田拓郎、西田基宏
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  長野県、松本市、信州大学
- Data Source
  KAKENHI-PROJECT-15K18883
[Presentation] Developmentally upregulated P2Y6 receptor promotes angiotensin II-induced hypertensive signaling.2016
- Author(s)
  Akiyuki Nishimura, Caloline Sunggip, Takuro Numaga-Tomita, Motohiro Nishida
- Organizer
  International and Interdisciplinary Symposium 2016
- Place of Presentation
  東京都、文京区、東京医科歯科大学
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18883
[Presentation] 加齢に伴うAT1R-P2Y6R複合体形成によるアンジオテンシンII誘発性高血圧の制御2016
- Author(s)
  西村明幸、Caroline Sunggip、冨田拓郎、西田基宏
- Organizer
  第63回中部日本生理学会
- Place of Presentation
  愛知県、岡崎市、岡崎コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-15K18883
[Presentation] Redox-dependent Regulation of H-Ras palmitoylation.2016
- Author(s)
  Akiyuki Nishimura, Tomoya Ito, Takuro Numaga-Tomita, Motohiro Nishida
- Organizer
  第9回国際NO学会　第16回日本NO学会
- Place of Presentation
  宮城県、仙台市、仙台国際センター
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18883
[Presentation] アンジオテンシンII誘発性高血圧に対するP2Y6受容体の役割2015
- Author(s)
  西村明幸、Caroline Sunggip、冨田拓郎、西田基宏
- Organizer
  第128回　日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15K18883
[Presentation] Purinergic P2Y6 receptor orchestrates angiotensin II-induced hypertension in mice
- Author(s)
  西村明幸、Sunggip Caloline、冨田（沼賀）拓郎、西田基宏
- Organizer
  第88回　日本薬理学会年会
- Place of Presentation
  名古屋国際会議場　（愛知県・名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26893325

1. Nishida Motohiro (90342641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 61 results
2. Tsutsui Hiroyuki (70264017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 康東天 (80214716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松島将士 (80552869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 井手友美 (90380625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HENGPHASATPORN Kowit (90961681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 加藤百合 (10732042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AMO Taku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. TORII Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. ITO Yurika

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. KANDA Yasunari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 西山和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
13. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
14. 鵜木隆光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 小島大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 本橋ほづみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 藤井重元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 冨田拓郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 池田宗一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 黒瀬等

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 井田智章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishimura Akiyuki 西村 明幸

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Regulation of cardiac robustness and metabolic flexibility based on protein supersulfidationPrincipal Investigator

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Novel signal regulation by G protein supersulfidation and its physiological role

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Mechanism of mitochondrial quality defects focusing on the linkage with the cytoskeleton and its application to the treatment of chronic diseasesPrincipal Investigator

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Regulation of mitochondrial redox by sulfiredoxin in cardiac remodeling

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Elucidation of mechanism underlying dysregulation of mitochondrial quality control in the failing heart and its therapeutic strategy

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Adaptation to Environmental stress and quality control of myocardial mitochondria by reactive sulfur speciesPrincipal Investigator

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Functional diversity and cardiac roles of purinergic P2Y6 receptorPrincipal Investigator

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心臓リモデリングにおけるプリン作動性受容体P2Y6の機能解析Principal Investigator

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[Book] Japanese Scientists in Science Signaling 2016「シグナリングに載った日本人研究者」2017

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[Journal Article] Cardiac Remodeling: Novel Pathophysiological Mechanisms and Therapeutic Strategies2024

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[Journal Article] 2H-Thiopyran-2-thione sulfine, a compound for converting H2S to HSOH/H2S2 and increasing intracellular sulfane sulfur levels2024

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[Journal Article] Supersulfide prevents cigarette smoke extract-induced mitochondria hyperfission and cardiomyocyte early senescence by inhibiting Drp1-filamin complex formation2024

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[Journal Article] Pharmacological Activation of TRPC6 Channel Prevents Colitis Progression2024

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[Journal Article] Echinochrome prevents sulfide catabolism-associated chronic heart failure after myocardial infarction in mice2023

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Nishimura Akiyuki 西村明幸