MASATO Watanbe 渡辺雅人

Researcher Number	00458902
Affiliation (based on the past Project Information) *help	2020 – 2023: 杏林大学, 医学部, 非常勤講師 2019: 杏林大学, 医学部, その他 2017 – 2019: 杏林大学, 医学部, 学内講師 2015 – 2016: 杏林大学, 医学部, 助教 2014: 杏林大学, 医学部, その他 2013 – 2014: 杏林大学, 医学部, 非常勤講師 2011 – 2012: 杏林大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / 膠原病・アレルギー・感染症内科学 Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator 好中球 / ST2 / sST2 / IL-33 / 喘息 / 生体イメージング / Intravital microscopy / Neutrophil / Asthma / バイオマーカー … More / 免疫 / 感染 / 気管支上皮細胞 / 重症喘息 / 肺炎 / 抗G-CSF自己抗体 / キャリアプロテイン / 市中肺炎 / 健常者 / IVIG / 細菌性肺炎 / 免疫複合体 / G-CSF / 自己抗体 … More Except Principal Investigator ST2 / マクロライド薬 / ウイルス感染症 / 自然免疫 / 好中球性炎症 / バイオマーカー / 増悪 / 抗炎症薬 / 細胞内シグナル / 気道炎症 / 難治性喘息 Less

Does sST2 inhalation therapy ameliorate severe neutrophilic asthma? Analysis of neutrophil functions using intravital microscopy.Principal Investigator
- Principal Investigator
  
  Masato Watanabe
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyorin University
sST2 is an important molecule in neutrophilic asthma: as a biomarker and a target for treatmentPrincipal Investigator
- Principal Investigator
  
  Watanabe Masato
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyorin University
Comprehensive approaches to pathopysiology and better treatment among severe asthma
- Principal Investigator
  
  Takizawa Hajime
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyorin University
Anti-G-CSF autoantibodies regulate neutrophil function in patiernt with bacterial pneumoniaPrincipal Investigator
- Principal Investigator
  
  MASATO Watanbe
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyorin University

All 2022 2021 2019 2018 2017 2016 2015 2013 2012

All Journal Article Presentation

[Journal Article] Soluble <scp>ST2</scp> enhances <scp>IL</scp> ‐33?induced neutrophilic and pro‐type 2 inflammation in the lungs2022
- Author(s)
  Watanabe Masato、Nakamoto Keitaro、Inui Toshiya、Sada Mitsuru、Chibana Kazuyuki、Miyaoka Chika、Yoshida Yuki、Aso Jumpei、Nunokawa Hiroki、Honda Kojiro、Nakamura Masuo、Tamura Masaki、Hirata Aya、Oda Miku、Takata Saori、Saraya Takeshi、Kurai Daisuke、Ishii Haruyuki、Takizawa Hajime
- Journal Title
  
  Allergy
  
  Volume: 77 Issue: 10 Pages: 3137-3141
- DOI
  10.1111/all.15401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0404
[Journal Article] Serum sST2 levels predict severe exacerbation of asthma2018
- Author(s)
  Watanabe Masato、Nakamoto Keitaro、Inui Toshiya、Sada Mitsuru、Honda Kojiro、Tamura Masaki、Ogawa Yukari、Yokoyama Takuma、Saraya Takeshi、Kurai Daisuke、Ishii Haruyuki、Takizawa Hajime
- Journal Title
  
  Respiratory Research
  
  Volume: 19 Issue: 1
- DOI
  10.1186/s12931-018-0872-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09628
[Journal Article] Serum Reactive Oxygen Metabolite Levels Predict Severe Exacerbations of Asthma.2016
- Author(s)
  Nakamoto K, Watanabe M, Sada M, Inui T, Nakamura M, Honda K, Wada H, Mikami Y, Matsuzaki H, Horie M, Noguchi S, Yamauchi Y, Koyama H, Kogane T, Kohyama T, Takizawa H.
- Journal Title
  
  PLoS One
  
  Volume: - Issue: 10 Pages: e0164948-e0164948
- DOI
  10.1371/journal.pone.0164948
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19172, KAKENHI-PROJECT-15K09189
[Journal Article] Clarithromycin ameliorates pulmonary inflammation induced by short term cigarette smoke exposure in mice.2015
- Author(s)
  Nakamura M, Wada H, Honda K, Nakamoto K, Inui T, Sada M, Watanabe M, Takata S, Yokoyama T, Saraya T, Kurai D, Ishii H, Goto H, Kamma H, Takizawa H.
- Journal Title
  
  Pulm Pharmacol Ther.
  
  Volume: 35 Pages: 60-66
- DOI
  10.1016/j.pupt.2015.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Soluble ST2 enhances IL-33-induced neutrophilic airway inflammation: a potential mechanism of neutrophilic asthma.2021
- Author(s)
  Masato Watanabe
- Organizer
  25th Congress of the APSR in Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0404
[Presentation] IL-33/sST2 balance regulates neutrophilic inflammation in the human airways.2019
- Author(s)
  4.M. Watanabe, K. Nakamoto, T. Inui, M. Sada, M. Oda, K. Honda, M. Tamura, H. Ishii, H. Takizawa
- Organizer
  ERS International Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] sST2/IL-33 balance regulates neutrophilic inflammation in the human airways.2018
- Author(s)
  Masato Watanabe, Toshiya Inui, Mitsuru Sada, Keitaro Nakamoto, Miku Oda, Yukari Ogawa,Takuma Yokoyama, Koujiro Honda, Takeshi Saraya, Daisuke Kurai, Haruyuki Ishii, and Hajime Takizawa.
- Organizer
  World Congress of Athma 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] Soluble ST2 (sST2)/ IL-33 balance regulates neutrophil-chemotaxis release from bronchial epithelial cells.2018
- Author(s)
  Masato Watanabe
- Organizer
  American Toracic Society 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] sST2/IL-33バランスは気管支上皮での好中球ケモカイン産生を制御する2018
- Author(s)
  渡辺　人
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] Soluble ST2 (sST2)/ IL-33 Balance Regulates Neutrophil Chemotaxis Release from Bronchial Epithelial Cells2018
- Author(s)
  Masato Watanabe, Mitsuru Sada, Keitaro Nakamoto, Toshiya Inui, Yukari Ogawa,Takuma Yokoyama, Koujiro Honda, Takeshi Saraya, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa
- Organizer
  2018 ATS International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] sST2/IL-33バランスは気管支上皮での好中球ケモカイン産生を制御する2018
- Author(s)
  渡辺雅人、中本啓太郎、佐田充、乾　俊哉、布川寛樹、麻生純平、田村仁樹、小田未来、小川ゆかり、本多紘二郎、横山　琢磨、皿谷　健、倉井大輔、石井晴之、滝澤　始
- Organizer
  日本呼吸器学会2018
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] LPS刺激による気道上皮細胞からのCXCL1産生2017
- Author(s)
  乾俊哉，渡辺雅人，佐田充，中本啓太郎，中村益夫，本多紘二郎，小川ゆかり，田村仁樹，横山琢磨，倉井大輔，皿谷健，石井晴之，滝澤始
- Organizer
  第66回日本感染症学会東日本地方会学術集会・第64回日本化学療法学会東日本支部総会合同学会，東京
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Bacterial and Viral Infection Enhances sST2 Production by Bronchial Epithelial Cells.2017
- Author(s)
  Watanabe M, Nakamoto K, Sada M, Inui T, Takata S, Yokoyama T, Saraya T, Ishii H, Takizawa H
- Organizer
  American Thoracic Society 2017 International Conference, Washington
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Serum sST2 levels predict severe exacerbation of asthma: A potential implication for neutrophilic asthma.2017
- Author(s)
  Masato Watanabe
- Organizer
  American Toracic Society 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] 成人喘息　病態気道上皮細胞におけるウイルス感染時のCCL5の発現とその制御機構の基礎的検討2017
- Author(s)
  佐田充，渡辺雅人，乾俊哉，中本啓太郎，滝澤始
- Organizer
  第66回日本アレルギー学会学術大会，東京
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Serum sST2 Levels Predict Severe Exacerbation of Asthma: A Potential Implication for Neutrophilic Asthma.2017
- Author(s)
  Watanabe M, Nakamoto K, Sada M, Inui T, Takata S, Yokoyama T, Saraya T, Kurai D, Ishii H, Takizawa H
- Organizer
  American Thoracic Society 2017 International Conference, Washington
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Bacterial and viral infection enhances sST2 production by bronchial epithelial cells2017
- Author(s)
  Masato Watanabe
- Organizer
  American Toracic Society 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09628
[Presentation] Upregulation of CCL5 production in the airway epithelium at the time of the viral infection.2016
- Author(s)
  Sada M, Watanabe M, Inui T, Nakamoto K, Nakamura M, Matsuzaki H, Yamauchi Y, Takizawa H
- Organizer
  ERS International Congress 2016
- Place of Presentation
  ロンドン、イギリス
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Reactive oxygen metabolite levels are surrogate biomarkers for predicting exacerbation of bronchial asthma.2016
- Author(s)
  Nakamoto k, Watanabe M, Sada M, Inui T, Ogawa Y, Nakamura M, Honda K, Koide T, Takata S, Yokoyama T, Saraya T, Kurai D, Wada H, Ishii H, Takizawa H
- Organizer
  ERS International Congress 2016
- Place of Presentation
  ロンドン、イギリス
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Regulation of GROα production in human bronchial epithelial cells.2016
- Author(s)
  Inui T, Watanabe M, Nakamoto K, Sada M, Tsuji S, Hirata A, Nakamura M, Ogawa Y, Koide T, Takata S, Yokoyama T, Kurai D, Saraya T, Ishii H, Wada H, Takizawa H
- Organizer
  ERS International Congress 2016
- Place of Presentation
  ロンドン、イギリス
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] Oxidative stress and biomarkers in patients with bronchial asthma.2015
- Author(s)
  Keitaro Nakamoto, Keitaro Nakamoto, Hiroo Wada, Shingo Tsuji, Mitsuru Sada, Toshiya Inui, Masuo Nakamura, Kojiro Honda, Yasutaka Tanaka, Takashi Koide, Saori Takata, Masato Watanabe, Takuma Yokoyama, Takeshi Saraya, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa
- Organizer
  European Respiratory Society International Congress
- Place of Presentation
  Amsterdam RAI, Netherands
- Year and Date
  2015-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09189
[Presentation] 市中肺炎（CAP）における抗G-CSF自己抗体の測定2013
- Author(s)
  渡辺雅人、田村仁樹、中村益夫、本多紘二郎、倉井大輔、和田裕雄、石井晴之、滝澤　始、後藤　元
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791119
[Presentation] Anti-Granulocyte-Colony Stimulating Factor Autoantibodies In Community Acquired Pneumonia: Novel Quantification Methods And A Possible Role Of The Autoantibodies.2012
- Author(s)
  Masato Watanabe, Masaki Tamura, Makiko Baba, Manabu Higaki, Tetsuo Yasutake, Masuo Nakamura, Koujiro Honda, Hajime Takizawa and Hajime Goto
- Organizer
  2012 International Conference of American thoracic Society
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-23791119

1. Takizawa Hajime (80171578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 皿谷健 (40549185)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. 田村仁樹 (80616607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 本多紘二郎 (20802995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. UCHIDA Kanji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAGAKI Kazuhide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKATA Koh

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. GOTO Hajime

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 滝沢始

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
10. 三上優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MASATO Watanbe 渡辺 雅人

Research Projects

Research Products

Co-Researchers

Does sST2 inhalation therapy ameliorate severe neutrophilic asthma? Analysis of neutrophil functions using intravital microscopy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

sST2 is an important molecule in neutrophilic asthma: as a biomarker and a target for treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive approaches to pathopysiology and better treatment among severe asthma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anti-G-CSF autoantibodies regulate neutrophil function in patiernt with bacterial pneumoniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Soluble <scp>ST2</scp> enhances <scp>IL</scp> ‐33?induced neutrophilic and pro‐type 2 inflammation in the lungs2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum sST2 levels predict severe exacerbation of asthma2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum Reactive Oxygen Metabolite Levels Predict Severe Exacerbations of Asthma.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clarithromycin ameliorates pulmonary inflammation induced by short term cigarette smoke exposure in mice.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Soluble ST2 enhances IL-33-induced neutrophilic airway inflammation: a potential mechanism of neutrophilic asthma.2021

Author(s)

Organizer

Data Source

[Presentation] IL-33/sST2 balance regulates neutrophilic inflammation in the human airways.2019

Author(s)

Organizer

Data Source

[Presentation] sST2/IL-33 balance regulates neutrophilic inflammation in the human airways.2018

Author(s)

Organizer

Data Source

[Presentation] Soluble ST2 (sST2)/ IL-33 balance regulates neutrophil-chemotaxis release from bronchial epithelial cells.2018

Author(s)

Organizer

Data Source

[Presentation] sST2/IL-33バランスは気管支上皮での 好中球ケモカイン産生を制御する2018

Author(s)

Organizer

Data Source

[Presentation] Soluble ST2 (sST2)/ IL-33 Balance Regulates Neutrophil Chemotaxis Release from Bronchial Epithelial Cells2018

Author(s)

Organizer

Data Source

[Presentation] sST2/IL-33バランスは気管支上皮での 好中球ケモカイン産生を制御する2018

Author(s)

Organizer

Data Source

[Presentation] LPS刺激による気道上皮細胞からのCXCL1産生2017

Author(s)

Organizer

Data Source

MASATO Watanbe 渡辺雅人

[Presentation] sST2/IL-33バランスは気管支上皮での好中球ケモカイン産生を制御する2018

[Presentation] sST2/IL-33バランスは気管支上皮での好中球ケモカイン産生を制御する2018

[Presentation] 成人喘息　病態気道上皮細胞におけるウイルス感染時のCCL5の発現とその制御機構の基礎的検討2017