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MIKURIYA Takefumi  御厨 剛史

ORCIDConnect your ORCID iD *help
Researcher Number 00467797
Affiliation (based on the past Project Information) *help 2008 – 2011: Yamaguchi University, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Otorhinolaryngology
Except Principal Investigator
Otorhinolaryngology
Keywords
Principal Investigator
熱ショック応答 / 老人性難聴 / 内耳保護 / 分子シャペロン / 熱ショック蛋白質 / 凝集体 / 老人性難徳 / 音響障害
Except Principal Investigator
熱ショック応答 / 加齢 / 熱ショック蛋白質 / 老化 / 内耳
  • Research Projects

    (3 results)
  • Research Products

    (46 results)
  • Co-Researchers

    (3 People)
  •  Study about the role of aggregations in age related healing loss model from the view of molecular chaperonPrincipal Investigator

    • Principal Investigator
      MIKURIYA Takefumi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamaguchi University
  •  The Relationship between Aging and Heat Shock Response in the Inner Ear

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamaguchi University
  •  Protection for inner ear against noise injury and aging by heat shock responsePrincipal Investigator

    • Principal Investigator
      MIKURIYA Takefumi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamaguchi University

All 2012 2011 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Geranylgeranylacetone suppresses noise-induced expression of proinflammatory cytokines in the cochlea2012

    • Author(s)
      Tetsuya Nakamoto, Takefumi Mikuriya, Kazuma Sugahara, Yoshinobu Hirose, Tomoko Hashimoto, Hiroaki Shimogori, Ryosuke Takii, Akira Nakai, Hiroshi Yamashita
    • Journal Title

      Auris Nasus Larynx

      Volume: 39 Pages: 270-274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Journal Article] Geranylgeranylacetone suppresses noise-induced expression of inflammatory cytokines in the cochlea2012

    • Author(s)
      中本, 御厨, ら
    • Journal Title

      Auris Nasas Larynx

      Volume: 39 Pages: 270-274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Journal Article] モルモット内有毛細胞のシナプス評価法の確立2012

    • Author(s)
      金川英寿、菅原一真、豊田英樹、御厨剛史、下郡博明、山下裕司
    • Journal Title

      頭頸部自律神経

      Volume: 26 Pages: 81-83

    • Data Source
      KAKENHI-PROJECT-22791606
  • [Journal Article] Geranylgeranylacetone suppresses noise-induced expression of proinflammatory cytokines in the cochlea2011

    • Author(s)
      Nakamoto T, Mikuriya T, Sugahara K, Hirose Y, Hashimoto T, Shimogori H, Takii R, Nakai A, Yamashita H
    • Journal Title

      Auris Nasus Larynx : Epub

      Volume: (Epub) Issue: 3 Pages: 270-274

    • DOI

      10.1016/j.anl.2011.06.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592157, KAKENHI-PROJECT-22591882
  • [Journal Article] 熱ショック蛋白質誘導剤(ゲラニルゲラニルアセトン)を用いた老人性難聴モデルマウスの難聴進行の抑制(解説)2010

    • Author(s)
      御厨剛史
    • Journal Title

      山口医学

      Volume: 59 Pages: 153-160

    • Data Source
      KAKENHI-PROJECT-22791606
  • [Journal Article] 熱ショック蛋白質誘導剤(ゲラニルゲラニルアセトン)を用いた老人性難聴モデルマウスの難聴進行の抑制2010

    • Author(s)
      御厨剛史
    • Journal Title

      山口医学

      Volume: 59 Pages: 153-160

    • NAID

      10030704702

    • Data Source
      KAKENHI-PROJECT-22791606
  • [Journal Article] 蝸牛における音響障害後の炎症性サイトカインの動向2010

    • Author(s)
      中本哲也、御厨剛史、菅原一真、下郡博明、山下裕司
    • Journal Title

      頭頸部自律神経 24

      Pages: 15-15

    • NAID

      10030883280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890146
  • [Journal Article] 熱ショック応答と内耳保護機能2009

    • Author(s)
      山下裕司, 御厨剛史
    • Journal Title

      耳鼻咽喉科展望

      Volume: 52 Pages: 10-16

    • Data Source
      KAKENHI-PROJECT-21592157
  • [Journal Article] 加齢における内耳熱ショック蛋白質発現の変化2009

    • Author(s)
      広瀬敬信, 菅原一真, 御厨剛史, 中本哲也, 橋本誠, 下郡博明, 山下裕司
    • Journal Title

      頭頸部自律神経第26回頭頸部自律神経研究会記録集

      Volume: 23 Pages: 33-35

    • Data Source
      KAKENHI-PROJECT-21592157
  • [Journal Article] 前庭感覚細胞死におけるBcl-xLの役割2009

    • Author(s)
      菅原一真, 宮内裕爾, 広瀬敬信, 御厨剛史, 橋本誠, 下郡博明, 山下裕司
    • Journal Title

      頭頸部自律神経第26回頭頸部自律神経研究会記録集

      Volume: 23 Pages: 30-32

    • Data Source
      KAKENHI-PROJECT-21592157
  • [Journal Article] 熱ショック応答と内耳保護機能2009

    • Author(s)
      山下裕司, 御厨剛史
    • Journal Title

      耳鼻咽喉科展望 52

      Pages: 10-16

    • Data Source
      KAKENHI-PROJECT-21592157
  • [Journal Article] 熱ショック応答と内耳保護機能2009

    • Author(s)
      山下裕司、御厨剛史
    • Journal Title

      耳鼻咽喉科展望 52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890146
  • [Journal Article] The Free Radical Scavenger Edaravone Protects Hair Cells aganist Aminoglycoside Toxicity.2008

    • Author(s)
      Tsuguyuki Arai, Kazuma Sugahara, Takefumi Mikuriya, Yuji Miyauchi, Yoshinobu Hirose, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Journal Title

      THE BULLETIN OF THE YAMAGUCHI MEDICAL SCHOOL 55

      Pages: 15-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890146
  • [Journal Article] 熱ショック応答誘導剤による内耳熱ショック応答の修飾と音響ストレスとの関係2008

    • Author(s)
      御厨剛史、菅原一真、広瀬敬信、下郡博明、山下裕司
    • Journal Title

      頭頸部自律神経 22

      Pages: 43-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890146
  • [Journal Article] 熱ショック応答誘導剤による内耳熱ショック応答の修飾と音響ストレスの関係2008

    • Author(s)
      御厨剛史, 他
    • Journal Title

      頭頸部自律神経 22

      Pages: 43-45

    • Data Source
      KAKENHI-PROJECT-20890146
  • [Journal Article] Effect of water-soluble coenzyme Q10 on noise-induced hearing loss in guinea pigs2008

    • Author(s)
      Yoshinobu Hirose, Kazuma Sugahara, Takefumi Mikuriya, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Journal Title

      Acta Oto-Laryngologica 128

      Pages: 1071-1076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890146
  • [Presentation] Relation Between Formation of Aggregations and Upregulation of Heart Shock Protein in Animal Models2012

    • Author(s)
      Kazuma Sugahara, Junko Tsuda, Eiju Kanagawa, Takefumi Mikuriya, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      35th Annual MidWinter Research Meeting of the Association for Research in Otolaryngology
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2012-02-25
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] Relation between formation of aggregations and upregulation of heart shock protein in animal models2012

    • Author(s)
      Mikuriya
    • Organizer
      Midwinter meeting of ARO
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-02-26
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] Relation between formation of aggregations and upregulation of heart shock protein in animal models2012

    • Author(s)
      Takefumi Mikuriya, Kazuma Sugahara, Yoshinobu Hirose, Eijyu Kanagawa, Syuuhei Yoshida, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      35th Annual MidWinter Research Meeting of the Association for Research in Otolaryngology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-02-25
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] Action of Substance P on the Recovery from the Acoustic Trauma2012

    • Author(s)
      Eiju Kanagawa, Kazuma Sugahara, Hideki Toyota, Takefumi Mikuriya, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      35th Annual MidWinter Research Meeting of the Association for Research in Otolaryngology
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2012-02-25
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] Age Related Hearing Loss in the Animal Model of Diabetes with Obesity2012

    • Author(s)
      Kazuma Sugahara, Junko Tsuda, Eiju Kanagawa, Takefumi Mikuriya, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      35th Annual MidWinter Research Meeting of the Association for Research in Otolaryngology
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2012-02-25
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] 熱ショック応答と蝸牛内凝集体形成についての関連についての検討2011

    • Author(s)
      御厨剛史, 菅原一真, 金川英寿, 津田潤子, 下郡博明, 山下裕司
    • Organizer
      第56回日本聴覚医学会総会・学術講演会
    • Place of Presentation
      福岡アクロス福岡
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] Effect of Substance P on the Recovery from the Acoustic Trauma2011

    • Author(s)
      Eiju Kanagawa, Kazuma Sugahara, Hideki Toyota, Takefumi Mikuriya, KenjiTakeno, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      34th ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Baltimore(USA)
    • Year and Date
      2011-02-19
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] Can Antidepressant Facilitate the Recovery of Peripheral Vestibular Function from Inner Ear Damage?2011

    • Author(s)
      Hiroaki Shimogori, Hideki Toyota, Kazuma Sugahara, Makoto Hashimoto, Takefumi Mikuriya, Hiroshi Yamashita
    • Organizer
      34th ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Baltimore(USA)
    • Year and Date
      2011-02-19
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] Intratympanic Free Radical Scavenger(Edaravone) as Rescue Therapy in Sudden Sensorineural Hearing Loss2011

    • Author(s)
      Kazuma Sugahara, Makoto Hashimoto, Takefumi Mikuriya, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      34th ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Baltimore(USA)
    • Year and Date
      2011-02-19
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] Incase of Aggregations After Noise Injury in Guinea Pig2011

    • Author(s)
      Takefumi Mikuriya, Kazuma Sugahara, Yoshinobu Hirose, Eiju Kanagawa, Syuhei Yoshida, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      34th ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Baltimore(USA)
    • Year and Date
      2011-02-19
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] Increase of aggregations after noise injury in guinea pig2011

    • Author(s)
      Takefumi Mikuriya
    • Organizer
      ARO 34th MidWinter Meeting
    • Place of Presentation
      Baltimore, Maryland, USA
    • Year and Date
      2011-02-20
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] Incase of Aggregations after noise injury in guinea pig2011

    • Author(s)
      Takefumi Mikuriya, Kazuma Sugahara, Yoshinobu Hirose, Eijyu Kanagawa, Syuuhei Yoshida, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      34th association for reseach in otolaryngology
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2011-02-19
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] The Change of Aggregations with Heat Shock Protein 70 in the Cochlea During Aging2010

    • Author(s)
      Takefumi Mikuriya, Kazuma Sugahara, Yoshinobu Hirose, Makoto Hashimoto, Tetsuya Nakamoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      33RD ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Anaheim(USA)
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] 進行性難聴モデルの蝸牛内凝集体についての研究2010

    • Author(s)
      御厨剛史
    • Organizer
      第4回聴覚アンチエイジング研究会
    • Place of Presentation
      東京都慶應義塾大学病院
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] The Expression of Proinflammatory Cytokines After Acoustic Overexposure2010

    • Author(s)
      Tetsuya Nakamoto, Takefumi Mikuriya, Kazuma Sugahara, Hiroshi Yamashita
    • Organizer
      33RD ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Anaheim(USA)
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] The Role of HSFI in the Maintenance of the Inner Ear Function2010

    • Author(s)
      Hiroshi Yamashita, Kazuma Sugahara, Takefumi Mikuriya, Yoshinobu Hirose, Hiroaki Shimogori
    • Organizer
      13th Korea-Japan Joint Meeting of Otorhinolaryngology-Head and Neck Surgery 2010
    • Place of Presentation
      Seoul(Korea)(講演)
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] 音響ストレス下での蝸牛内凝集体形成についての検討2010

    • Author(s)
      御厨剛史, 菅原一真, 金川英寿, 橋本誠, 下郡博明, 山下裕司
    • Organizer
      第55回日本聴覚医学会総会・学術講演会
    • Place of Presentation
      奈良奈良県新公会堂
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] The Protection of Vestibular Hair Cells with Resveratrol2010

    • Author(s)
      Kazuma Sugahara, Takefumi Mikuriya, Yoshinobu Hirose, Yujirou Fukuda, Hideki Toyota, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      33RD ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Anaheim(USA)
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] The Protective Effect of Resveratrol against the Hair Cell Degeneration Induced by Neomycin2010

    • Author(s)
      Kazuma Sugahara, Takefumi Mikuriya, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      Sixth International Symposium onMeniere' s Disease and Inner Ear Disorders
    • Place of Presentation
      国立京都国際会館京都(講演)
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] 音響ストレス下での蝸牛内凝集体形成についての検討2010

    • Author(s)
      御厨剛史
    • Organizer
      第55回聴覚医学会
    • Place of Presentation
      奈良県奈良市新公会堂
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] 進行性難聴モデルの蝸牛内凝集体についての検討2010

    • Author(s)
      御厨剛史, 菅原一真, 広瀬敬信, 山下裕司
    • Organizer
      第4回聴覚アンチエイジング研究会
    • Place of Presentation
      東京慶應義塾大学病院
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] 内耳熱ショック蛋白質と凝集体についての検討2010

    • Author(s)
      御厨剛史, 菅原一真, 下郡博明, 山下裕司
    • Organizer
      第111回日本耳鼻咽喉科学会総会・学術講演会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] 熱ショック蛋白質誘導剤(ゲラニルゲラニルアセトン)を用いた老人性難聴モデルマウスの難聴進行の抑制2010

    • Author(s)
      御厨剛史
    • Organizer
      第114回山口大学医学会学術講演会
    • Place of Presentation
      宇部山口大学
    • Year and Date
      2010-07-17
    • Data Source
      KAKENHI-PROJECT-22791606
  • [Presentation] Can Inner Ear ApPlication of Rolipram, a P-CREB Up-Regurator, Induce Phosphorylation of CREB in Vestibular Ganglion Cells?2010

    • Author(s)
      Hiroaki Shimogori, Hideki Toyota, Kazuma Sugahara, Makoto Hashimoto, Takefumi Mikuriya, Yoshinobu Hirose, Hiroshi Yamashita
    • Organizer
      33RD ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    • Place of Presentation
      Anaheim(USA)
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] The protective effect of resveratrol on vestibular hair cells death2010

    • Author(s)
      Kazuma Sugahara, Takefumi Mikuriya, Yoshinobu Hirose, Yujirou Fukuda, Hideki Toyota, Kenji Takeno, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      26th Barany Society Meeting
    • Place of Presentation
      Reykjavik(lceland)(海外招待講演)
    • Year and Date
      2010-08-18
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] The oral administration of tePrenone can protect the vestibular hair cells2009

    • Author(s)
      Kazuma Sugahara, Takefumi Mikuriya, Yoshinobu Hirose, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
    • Organizer
      第19回IFOS 2009 BRAZIL
    • Place of Presentation
      Sao Paulo(Brazil)
    • Year and Date
      2009-06-01
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] The Role of HSFI in the Maintenance of the Inner Ear Function2009

    • Author(s)
      Hiroshi Yamashita, Kazuma Sugahara, Takefumi Mikuriya, Yoshinobu Hirose, Hiroaki Shimogori, Akira Nakai
    • Organizer
      10th Taiwan Japan Otolaryngology Head & Neck Conference
    • Place of Presentation
      Yilan(Taiwan)(講演)
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-21592157
  • [Presentation] 加齢による内耳熱ショック蛋白質の変化について2009

    • Author(s)
      御厨剛史
    • Organizer
      第54回日本聴覚医学会総会・学術講演会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-20890146
  • [Presentation] マウス音響障害モデルの熱ショック応答の評価と系統間による誘導の違いの検討2008

    • Author(s)
      御厨剛史
    • Organizer
      第18回学術講演会・耳科学会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-20890146
  • [Presentation] マウス音響障害モデルの熱ショック応答の評価と系統間による誘導の違いの検討2008

    • Author(s)
      御厨剛史, 他
    • Organizer
      第18回学術講演会・耳科学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-20890146
  • 1.  YAMASHITA Hiroshi (00210419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 2.  SHIMOGORI Hiroaki (70226273)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 3.  SUGAHARA Kazuma (20346555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results

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