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LIN QINGSHUN  林 青順

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LIN Qingshun  林 青順

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Researcher Number 00468589
Affiliation (based on the past Project Information) *help 2016: 桐蔭横浜大学, 医用工学部, 客員研究員
2014 – 2015: 順天堂大学, 医学部, 助教
2008 – 2009: Juntendo University, 医学部, 助教
Review Section/Research Field
Principal Investigator
Experimental pathology
Keywords
Principal Investigator
B細胞 / monocyte/マクロファージ / サイトカイン / B細胞の自己免疫寛容破綻 / Monocyte/マクロファージ / 細胞特異的FcγRIIB欠損マウス / FcγRIIB / IL-1β,IL-10,CLcf1 / RNA-seq / 単球 … More / FcgRIIB発現欠損 / IL-1b,IL-10,CLcf1 / B細胞活性化因子 / 樹状細胞 / 単球/マクロファージ / 細胞特異的FcγRIIB欠損 / 自己免疫寛容破綻 / ループス腎炎 / Fcgr2b遺伝子 / BXSB / 遺伝要因 / 移植実験 / 形質細胞 / 感受性遺伝子 / 胚中心B細胞 / FcγRIIB発現 / Fcgr2b遺伝子多型 / SLE Less
  • Research Projects

    (2 results)
  • Research Products

    (15 results)
  •  Cell type-specific role of inhibitory IgG Fc receptor IIB in murine lupusPrincipal Investigator

    • Principal Investigator
      LIN QINGSHUN
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Toin University of Yokohama
      Juntendo University
  •  The mechanism for plasma cell differentiation which controlled by inhibitory FcγRIIB expressionPrincipal Investigator

    • Principal Investigator
      LIN Qingshun
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Juntendo University

All 2016 2015 2010 2009 2008 Other

All Journal Article Presentation

  • [Journal Article] Inhibitory IgG Fc receptor promoter region polymorphism is a key genetic formurine systemic lupus erythematosus.2010

    • Author(s)
      Lin Q, et al.
    • Journal Title

      J.Autoimmun. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Journal Article] Inhibitory IgG Fc receptor promoter region polymorphism is a key genetic for murine systemic lupus erythematosus2010

    • Author(s)
      Qingshun Lin, Rong Hou, Aya Sato, Mareki Ohtsuji, Naomi Ohtsuji, Keiko Nishikawa, Hiromichi Tsurui, Hirofumi Amano, Eri Amano, Katsuko Sudo, Hiroyuki Nishimura, Toshikazu Shira, SachikoHirose
    • Journal Title

      J. Autoimmun. 34(4)

      Pages: 356-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Journal Article] FTY720 exerts a survival advantage through the prevention of end-stage glomerular inflammation in lupus-prone BXSB mice. Biochem.2010

    • Author(s)
      Ando S, Amano H, Amano E, Minowa K, Watanabe T, Nakano S, Nakiri Y, Morimoto S, Tokano Y, Lin Q, Hou R, Ohtsuji M, Tsurui H, Hirose S, Takasaki Y.
    • Journal Title

      Biophys. Res. Commun. 394(3)

      Pages: 804-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Journal Article] Ankylosing enthesitis associated with up-regulated IFN-・and IL-17 production in (BXSB x NZB) F1 male mice; a new mouse model2009

    • Author(s)
      Abe Y, Ohtsuji M, Ohtsuji N, Lin Q, Tsurui H, Nakae S, Shirai T, Sudo K, Hirose S.
    • Journal Title

      Mod. Rheumatol. 19(3)

      Pages: 316-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Journal Article] Fcgamma receptordependent expansion of a hyperactive monocyte subset in lupus-prone mice2009

    • Author(s)
      Santiago-Raber ML, Amano H, Amano E, Baudino L, Otani M, Lin Q, Nimmerjahn F, Ferbeek JS, Ravetch JF, Takasaki Y, Hirose S, Izui S.
    • Journal Title

      Arthritis Rheum. 60(8)

      Pages: 2408-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Journal Article] Aberrant genetic control of invariant TCR-bearing NKT cell function in New Zealand mouse strains: possible involvement in systemic lupus erythematosus pathogenesis2008

    • Author(s)
      Tsukamoto K, Ohtsuji M, Shiroiwa W, Lin Q, Nakamura K, Tsurui H, Jiang Y, Sudo K, Nishimura H, Shirai T, Hirose S.
    • Journal Title

      J. Immunol. 180(7)

      Pages: 4530-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Presentation] Inhibitory IgG Fc receptor IIB on B cells and monocytes independenly controls Yaa-induced murine lupus2016

    • Author(s)
      LIN Qingshun, TSURUI Hiromichi, NISHIKAWA Keiko, AMANO Hirohumi, OHTSUJI Mareki, NISHIMURA Hiroyuki, J.Sjef.Verbeek, HIROSE Sachiko
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2016-12-04
    • Data Source
      KAKENHI-PROJECT-26460493
  • [Presentation] 細胞特異的FcγFIIB発現欠損マウスを用いたループス腎炎発症機序の解明2016

    • Author(s)
      林 青順, 西川 桂子, 天野 浩文, 大辻 希樹, 西村 裕之, 白井 俊一, 広瀬 幸子
    • Organizer
      第59回日本リウマチ学会総会・学術集会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2016-04-24
    • Data Source
      KAKENHI-PROJECT-26460493
  • [Presentation] Cell type-specific role of inhibitory IgG Fc receptor IIB in Yaa-induced murine lupus2015

    • Author(s)
      LIN Qingshun, TSURUI Hiromichi, NISHIKAWA Keiko, AMANO Hirohumi, OHTSUJI Mareki, NISHIMURA Hiroyuki, SHIRAI Toshikazu, J.Sjef.Verbeek , HIROSE Sachiko
    • Organizer
      第44回日本免疫学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26460493
  • [Presentation] Fcgr2b多型は自己反応性B細胞の寛容破綻の遺伝要因である2009

    • Author(s)
      Lin Q, et al.
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪・大阪国際会議場
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Presentation] Fcgr2b promoter region polymorphism is a key genetic element for breakdown of self-reactive B cell tolerance2009

    • Author(s)
      Lin Q, Hou Rong, Sato Aya, Tsurui Hiromichi、Ohtsuji Mareki、Ohtsuji Naomi、Nishikawa Keiko、Nishimura Hiroyuki、Sudo Keiko、Shirai Toshikazu、Hirose Sachiko
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪・大阪国際会場
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Presentation] The role of Fcgr2b promoter region polymorphism in (NZW x BXSB)F1 mice.2008

    • Author(s)
      Lin Q、Hiromichi Tsurui、Mareki Ohtsuji、Hirofumi Amano、Hiroyuki Nishimura、Toshikazu Shirai、Sachiko Hirose.
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      京都・国立京都国際会館
    • Year and Date
      2008-12-03
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Presentation] (NZW x BXSB)F1マウスにおけるFcgr2bプロモター領域の多型性の影響2008

    • Author(s)
      Lin Qingshun
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      京都・国立京都国際会館
    • Year and Date
      2008-12-03
    • Data Source
      KAKENHI-PROJECT-20790311
  • [Presentation] 細胞特異的FcγRIIB発現欠損マウス系の樹立によるYaa誘導ループス腎炎発症機序の解明

    • Author(s)
      林 青順, 西川 桂子, 天野 浩文, 大辻 希樹, 西村 裕之、白井 俊一, 広瀬 幸子
    • Organizer
      第59回リウマチ学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-04-23 – 2015-04-25
    • Data Source
      KAKENHI-PROJECT-26460493
  • [Presentation] B cell specific FcγRIIb deficiency is enough for autoantibody production, but not for the progression of Yaa-related severe lupus nephritis

    • Author(s)
      LIN Qingshun, TSURUI Hiromichi, NISHIKAWA Keiko, AMANO Hirohumi, OHTSUJI Mareki, NISHIMURA Hiroyuki, SHIRAI Toshikazu, J. Sef. Verbeek, HIROSE Sachiko
    • Organizer
      第免43回疫学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-26460493

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