KAWAHARA Akihiro 河原明彦

Researcher Number	00469347
Affiliation (Current)	2025: 久留米大学, 大学病院, 医療技術員
Affiliation (based on the past Project Information) *help	2016 – 2024: 久留米大学, 大学病院, 医療技術員 2014 – 2015: 久留米大学, 大学病院, その他 2011 – 2013: 久留米大学, 大学病院, 臨床検査技師 2010 – 2011: 久留米大学, 大学病院, その他
Review Section/Research Field	Principal Investigator Human pathology Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Radiation science / Basic Section 55020:Digestive surgery-related / Basic Section 57060:Surgical dentistry-related / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 分子病理学 / 病理学 / 肺癌 / 液状化細胞診 / 上澄みDNA / 細胞診 / 分子病理学的検査 / 体腔液細胞診 / EGFR遺伝子変異 / 遊離DNA … More / 免疫組織・細胞化学 / EGFR　遺伝子変異 / 病理 / 遺伝子検査 / 癌 / EGFR遺伝子変異抗体 / 免疫染色 … More Except Principal Investigator PET/CT / Evaluation Platform / TIME / Esophageal Cancer / 免疫チェックポイント分子 / 口腔扁平上皮癌 / クロストーク解析 / がん幹細胞 / ALOX12 / フェロトーシス / 抗がん剤耐性 / 膵がん / 細胞周期 / 卵巣癌 / YBX1 / FMISO PET/CT / 食道癌 / 免疫チェックポイント阻害剤 / 術前化学療法 / 低酸素 / FMISO / メチオニン / 神経膠腫 / 核医学 / 癌シグナル伝達遺伝子 / 癌シグナル伝達因子 / アミノ酸イメージング / 脳腫瘍 / SPIO / Kuffer機能 / NASH / 病理像 / Kupffer細胞 / CD68 / CD14 / MRI / 非アルコール性脂肪肝炎 / CD14抗体 / Kupffer機能 / 単純性脂肪肝 / 非アルコール性脂肪肝炎(NASH) / SPIO造影MRI Less

Development of novel therapeutic approach for ovarian clear cell carcinoma targeting cell cycle regulation by A.
- Principal Investigator
  
  村上雄一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Our Lady of the Snow Social Medical Corporation (St. Mary
Development of novel chemotherapy to selectively induce ferroptosis in pancreatic cancer cells by targeting ALOX12
- Principal Investigator
  
  松本太一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Our Lady of the Snow Social Medical Corporation (St. Mary
口腔癌の癌幹細胞と周囲微小環境とのクロストーク機構解析による新規治療戦略の確立
- Principal Investigator
  
  轟圭太
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kurume University
食道癌のTIME自動診断のプラットフォーム開発に関する研究
- Principal Investigator
  
  主藤朝也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kurume University
食道癌術前化学療法の治療効果予測―低酸素イメージングと癌シグナル伝達因子との相関
- Principal Investigator
  
  甲斐田勇人
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kindai University
To elucidate the prognostic marker using amino acid PET imaging and signal transduction factors in brain tumor patients
- Principal Investigator
  
  KAIDA HAYATO
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kindai University
Establish of new detection method of gene mutations using cell-free DNA in supernatant fluidsPrincipal Investigator
- Principal Investigator
  
  kawahara akihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kurume University
Establish of new deteciton of EGFR mutation status using immunostaining in non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  KAWAHARA Akihiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kurume University
CD14 expression and Kupffer cell dysfunction in non-alcoholic steatohepatitis : Superparamagnetic iron oxide-magnetic resonance image and pathologic correlation
- Principal Investigator
  
  FUJIMOTO Kiminori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kurume University

All 2024 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] EGFR mutation status in cell-free DNA supernatant of bronchial washings and brushings.2015
- Author(s)
  Kawahara A, Fukumitsu C, Taira T, Abe H, Takase Y, Mutara K, Yamaguchi T, Azuma K, Ishii H, Takamori S, Akiba J, Hoshono T, Kage M.
- Journal Title
  
  Cancer Cytopathology
  
  Volume: 123 Issue: 10 Pages: 620-628
- DOI
  10.1002/cncy.21583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460462
[Journal Article] Evaluation of immunohistochemistry using two different antibodies and procedures for primary lung adenocarcinoma harboring anaplastic lymphoma kinase rearrangement2014
- Author(s)
  Akiba J, Kawahara A, Abe H, Azuma K, Yamaguchi T, Taira T, Fukumitsu C, Takase Y, Yasumoto M, Umeno Y, Todoroki K, Kurita T, Yamaguchi R, Kage M, Yano H
- Journal Title
  
  Oncol Letters
  
  Volume: 8 Issue: 5 Pages: 2155-2159
- DOI
  10.3892/ol.2014.2511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460462
[Journal Article] EML4-ALK-positive lung adenocarcinoma with signet-ring cells2014
- Author(s)
  Kawahara A, Akiba J, Abe H, Yamaguchi T, Taira T, Azuma K, and Kage M
- Journal Title
  
  Diagnostic cytopathology
  
  Volume: 42 Issue: 5 Pages: 460-463
- DOI
  10.1002/dc.22936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460462
[Journal Article] Humoral immune responses to EGFR-derived peptides predict progression-free and overall survival of non-small cell lung cancer patients receiving gefitinib.2014
- Author(s)
  Azuma K, Komatsu N, Hattori S, Matsueda S, Kawahara A, Sasada T, Itoh K, Hoshino T.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 1 Pages: e86667-e86667
- DOI
  10.1371/journal.pone.0086667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591913, KAKENHI-PROJECT-26460462
[Journal Article] FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor2014
- Author(s)
  Azuma K, Kawahara A, Sonoda K, Nakashima K, Tashiro K, Watari K, Izumi H, Kage M, Kuwano M, Ono M, Hoshino T
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 5908-5919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460462
[Journal Article] Fixation effect of SurePath preservative fluids using EGFR mutation-specific antibodies for immunocytochemistry.2014
- Author(s)
  Kawahara A, Taira T, Abe H, Watari K, Murakami Y, Fukumitsu C, Takase Y, Yamaguchi T, Akiba J, Azuma K, Ono M, Kage M
- Journal Title
  
  Cancer Cytopathology
  
  Volume: 122 Issue: 2 Pages: 145-152
- DOI
  10.1002/cncy.21355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460462
[Journal Article] Expression of Monocarboxylate Transporter (MCT)-4 in Colorectal Cancer and its Role: MCT4 Contributes to the Growth of Colorectal Cancer with Vascular Endothelial Growth Factor.2013
- Author(s)
  Gotanda Y, Akagi Y, Kawahara A, Kinugasa T, Yoshida T, Ryu Y, Shiratsuchi I, Kage M, Shirouzu K.
- Journal Title
  
  Anticancer research
  
  Volume: 33 Pages: 2941-2947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] FOXP3 expression in tumor cells and tumor-infiltrating lymphocytes is associated with breast cancer prognosis2013
- Author(s)
  Miki Takenaka, Naoko Seki, Uhi Toh, Satoshi Hattori, Akihiko Kawahara, Tomohiko Yamaguchi, Keiko Koura, Ryuji Takahashi, Hiroko Otsuka, Hiroki Takahashi, Nobutaka Iwakuma, Shino Nakagawa, Teruhiko Fujii, Tetsuro Sasada, Rin Yamaguchi, Hirohisa Yano, Kazuo Shirouzu, Masayoshi Kage
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 1 Issue: 4 Pages: 625-632
- DOI
  10.3892/mco.2013.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591912, KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24591925
[Journal Article] Potential usefulness of mucin immunohistochemical staining of preoperative pancreatic biopsy or juice cytology specimens in the determination of treatment strategies for intraductal papillary mucinous neoplasm.2013
- Author(s)
  Hisaka T, Horiuchi H, Uchida S, Ishikawa H, Kawahara R, Kawashima Y, Akashi M, Mikagi K, Ishida Y, Okabe Y, Nakayama M, Naito Y, Yano H, Taira T, Kawahara A, Kage M, Kinoshita H, Shirozu K.
- Journal Title
  
  Oncology Reports
  
  Volume: 30 Issue: 5 Pages: 2035-2041
- DOI
  10.3892/or.2013.2720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] The relationship between 18F-FDG metabolic volumetric parameters and clinicopathological factors of breast cancer.2013
- Author(s)
  Kaida H, Toh U, Hayakawa M, Hattori S, Fujii T, Kurata S, Kawahara A, Hirose Y, Kage M, Ishibashi M.
- Journal Title
  
  Nuclear medicine communications
  
  Volume: 34 Issue: 6 Pages: 562-570
- DOI
  10.1097/mnm.0b013e328360d945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells2013
- Author(s)
  Murakami, Y., Watari, K., Ono, M, et al. 計11名
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 35 Pages: 25025-25037
- DOI
  10.1074/jbc.m113.472068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300350, KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24650646, KAKENHI-PROJECT-25830083
[Journal Article] Phase II study of personalized peptide vaccination for refractory bone and soft tissue sarcoma patients.2013
- Author(s)
  Takahashi R, Ishibashi Y, Hiraoka K, Matsueda S, Kawano K, Kawahara A, Kage M, Ohshima K, Yamanaka R, Shichijo S, Shirouzu K, Itoh K, Sasada T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 10 Pages: 1285-1294
- DOI
  10.1111/cas.12226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591913, KAKENHI-PROJECT-23659695, KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24390347
[Journal Article] A case of mucoepidermoid carcinoma which could be diagnosed by liquid based bronchial brushing cytology2013
- Author(s)
  福満千容,河原明彦,山口知彦,安倍秀幸,多比良朋希,高瀬頼妃呼,秋葉純,鹿毛政義
- Journal Title
  
  The Journal of the Japanese Society of Clinical Cytology
  
  Volume: 52 Issue: 5 Pages: 473-477
- DOI
  10.5795/jjscc.52.473
- NAID
  10031191694
- ISSN
  0387-1193, 1882-7233
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Treatment outcome in patients with stage III breast cancer treated with neoadjuvant chemotherapy.2013
- Author(s)
  Takahashi R, Toh U, Iwakuma N, Mishima M, Fujii T, Takenaka M, Koura K, Seki N, Kawahara A, Kage M, Ogo E, Shirouzu K.
- Journal Title
  
  Experimental and therapeutic medicine
  
  Volume: 6 Issue: 5 Pages: 1089-1095
- DOI
  10.3892/etm.2013.1289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Y-box binding protein-1 (YB-1) contributes to both HER2/ErbB2 expression and lapatinib sensitivity in human gastric cancer cells.2013
- Author(s)
  Shibata T, Kan H, Murakami Y, Ureshino H, Watari K, Kawahara A, Kage M, Hattori S, Ono M, Kuwano M.
- Journal Title
  
  Molecular cancer therapeutics
  
  Volume: 12 Issue: 5 Pages: 737-746
- DOI
  10.1158/1535-7163.mct-12-1125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24650646
[Journal Article] Clinicopathological significance of hypoxia-inducible factor-1 alpha (HIF-1α) expression in gastric cancer.2013
- Author(s)
  Isobe T, Aoyagi K, Koufuji K, Shirouzu K, Kawahara A, Taira T, Kage M.
- Journal Title
  
  International journal of clinical oncology
  
  Volume: 18 Issue: 2 Pages: 293-304
- DOI
  10.1007/s10147-012-0378-8
- NAID
  10031176269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Prognostic Value of EGFR Mutation and ERCC1 in Patients with Non-Small Cell Lung Cancer Undergoing Platinum-Based Chemotherapy.2013
- Author(s)
  Yamashita F, Azuma K, Yoshida T, Yamada K, Kawahara A, Hattori S, Takeoka H, Zaizen Y, Kawayama T, Kage M, Hoshino T.
- Journal Title
  
  PLoS ONE
  
  Volume: 5 Issue: 8 Pages: e71356-e71356
- DOI
  10.1371/journal.pone.0071356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Erlotinib resistance in lung cancer cells mediated by integrinβ1/Src/Akt-driven bypass signaling2013
- Author(s)
  Kanda, R., Kage, M., Ono M, et al. 計12名
- Journal Title
  
  Cancer Res
  
  Volume: 73 Issue: 20 Pages: 6243-6253
- DOI
  10.1158/0008-5472.can-12-4502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300350, KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24650646, KAKENHI-PROJECT-25462190
[Journal Article] Comparison of adverse events and efficacy between gefitinib and erlotinib in patients with non-small-cell lung cancer : a retrospective analysis2013
- Author(s)
  Yoshida T, Yamada K, Azuma K, Kawahara A, Abe H, Hattori S, Yamashita F, Zaizen Y, Kage M, Hoshino T
- Journal Title
  
  Med Oncol
  
  Volume: 30巻 Issue: 1 Pages: 349-349
- DOI
  10.1007/s12032-012-0349-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] A case of metastasizing pleomorphic adenoma in the maxillary bone appearing twenty years after initial resection of pleomorphic adenoma of the hard palate.2013
- Author(s)
  Akiba J, Harada H, Kawahara A, Todoroki K, Nagata S, Yano H.
- Journal Title
  
  Pathology international
  
  Volume: 63 Issue: 9 Pages: 463-368
- DOI
  10.1111/pin.12087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] A case of primary lung cancer with EGFR mutation which needed to be distinguished from lung metastasis of breast cancer2012
- Author(s)
  河原明彦,山口知彦,安倍秀幸,多比良朋希,吉田友子,内藤嘉紀,秋葉純,鹿毛政義
- Journal Title
  
  The Journal of the Japanese Society of Clinical Cytology
  
  Volume: 51 Issue: 2 Pages: 120-124
- DOI
  10.5795/jjscc.51.120
- NAID
  130004513125
- ISSN
  0387-1193, 1882-7233
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Prognostic significance of total lesion glycolysis in patients with advanced non-small cell lung cancer receiving chemotherapy.2012
- Author(s)
  Zaizen Y, Azuma K, Kurata S, Sadashima E, Hattori S, Sasada T, Imamura Y, Kaida H, Kawahara A, Kinoshita T, Ishibashi M, Hoshino T.
- Journal Title
  
  Eur J Radiol.
  
  Volume: 81 Issue: 12 Pages: 4179-84
- DOI
  10.1016/j.ejrad.2012.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591913, KAKENHI-PROJECT-23790425
[Journal Article] Loss of Activating EGFR Mutant Gene Contributes to Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer Cells2012
- Author(s)
  Tabara K, Kanda R, Sonoda K, Kubo T, Murakami Y, Kawahara A, Azuma K, Abe H, Kage M, Yoshinaga A, Tahira T, Hayashi K, Arao T, Nishio K, Rosell R, Kuwano M, Ono M
- Journal Title
  
  PLoS One
  
  Volume: 7巻 Issue: 7 Pages: e41017-e41017
- DOI
  10.1371/journal.pone.0041017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24650646
[Journal Article] NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer2012
- Author(s)
  Azuma, K., Kawahara, A., Hattori, S., Taira, T., Tsurutani, J., Watari, K., Shibata, T., Murakami, Y., Takamori, S., Ono, M., Izumi, H., Kage, M., Yanagawa, T., Nakagawa, K., Hoshino, T., Kuwano, M.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: (In press) Issue: 5 Pages: 779-789
- DOI
  10.1097/jto.0b013e31824c92b4
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112515, KAKENHI-PROJECT-23300350, KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24650646
[Journal Article] CD14 expression and Kupffer cell dysfunction in non-alcoholic steatohepatitis : superparamagnetic iron oxide-magnetic resonance image and pathologic correlation2012
- Author(s)
  Tonan T, Fujimoto K, Qayyum A, Morita Y, Nakashima O, Ono N, Kawahara A, Kage M, Hayabuchi N, Ueno T.
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 27(4) Issue: 4 Pages: 789-796
- DOI
  10.1111/j.1440-1746.2011.07057.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591584
[Journal Article] A diagnostic algorithm using EGFR mutation-specific antibodies for rapid response EGFR-TKI treatment in patients with non-small cell lung cancer.2012
- Author(s)
  Kawahara A, Taira T, Azuma K, Tominaga M, Hattori S, Kawahara M, Abe H, Yamaguchi T, Akiba J, Takamori S, Hayashi A, Kage M.
- Journal Title
  
  Lung Cancer.
  
  Volume: 78 Pages: 39-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] A diagnostic algorithm using EGFR mutation-specific antibodies for rapid response EGFR-TKI treatment in patients with non-small cell lung cancer2012
- Author(s)
  Kawahara A, Taira T, Azuma K, Tominaga M, Hattori S, Kawahara M, Abe H, Yamaguchi T, Akiba J, Takamori S, Hayashi A, Kage M
- Journal Title
  
  Lung Cancer
  
  Volume: 78巻 Issue: 1 Pages: 39-44
- DOI
  10.1016/j.lungcan.2012.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Immunological evaluation of personalized peptide vaccination in refractory small cell lung cancer.2012
- Author(s)
  Terazaki Y, Yoshiyama K, Matsueda S, Watanabe N, Yamada A, Mine T, Terasaki M, Itoh K, Takamori S, Sasada T.
- Journal Title
  
  Cancer Sci
  
  Volume: 103(4) Issue: 4 Pages: 638-644
- DOI
  10.1111/j.1349-7006.2012.02202.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501292, KAKENHI-PROJECT-23591913, KAKENHI-PROJECT-23790425
[Journal Article] Chemotherapy for non-small cell lung cancer complicated by idiopathic interstitial pneumonia2012
- Author(s)
  Kinoshita T, Azuma K, Sasada T, Okamoto M, Hattori S, Imamura Y, Yamada K, Tajiri M, Yoshida T, Zaizen Y, Kawahara A, Fujimoto K, Hoshino T
- Journal Title
  
  Oncol Lett
  
  Volume: 4巻 Issue: 3 Pages: 477-482
- DOI
  10.3892/ol.2012.753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Comparison of the expression levels of napsin A, thyroid transcription factor-1, and p63 in nonsmall cell lung cancer using cytocentrifuged bronchial brushings2011
- Author(s)
  Aikawa E, Kawahara A, Hattori S, Yamaguchi T, Abe H, Taira T, Azuma K, Kage M
- Journal Title
  
  Cancer Cytopathol
  
  Volume: 119巻 Issue: 5 Pages: 335-340
- DOI
  10.1002/cncy.20162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Association of the expression of mutant epidermal growth factor receptor protein as determined with mutation-specific antibodies in non-small cell lung cancer with progression-free survival after gefitinib treatment2011
- Author(s)
  Azuma, K., Okamoto, I., Kawahara, A., Taira, T., Nakashima, K., Hattori. S., Kinoshita, T., Takeda, M., Nakagawa, K., Takamori, S., Kuwano, M., Ono, M., Kage, M.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 6 Issue: 1 Pages: 122-127
- DOI
  10.1097/jto.0b013e31822eeba2
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112515, KAKENHI-PROJECT-23300350, KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24650646
[Journal Article] Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid: Rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry.2011
- Author(s)
  Kawahara A.
- Journal Title
  
  Lung Cancer.
  
  Volume: 73 Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Journal Article] Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid : Rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry2011
- Author(s)
  Kawahara A, Azuma K, Sumi A, Taira T, Nakashima K, Aikawa E, Abe H, Yamaguchi T, Takamori S, Akiba J, Kage M
- Journal Title
  
  Lung Cancer
  
  Volume: 74巻 Issue: 1 Pages: 35-40
- DOI
  10.1016/j.lungcan.2011.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] An initial prospective clinical study of tumor hypoxia evaluated with 18F-fluoromisonidazole PET/CT in esophageal cancer patients undergoing neoadjuvant chemotherapy2024
- Author(s)
  Hayato Kaida, Osamu Shiraishi, Hiroaki Kato, Kohei Hanaoka, Akihiko Kawahara, Satoshi Hattori, Makoto Hosono, Akihiko Ito, Takushi Yasuda , Kazunari Ishii
- Organizer
  第84回日本医学放射線学会総会
- Data Source
  KAKENHI-PROJECT-21K07630
[Presentation] Detection of EGFR mutation status in cell-free DNA supernatant of effusion cytology2016
- Author(s)
  Kawahara Akihiko,　Fukumitsu Chihiro, Taira Tomoki, Abe Hideyuki, Takase Yorihiko, Murata Kazuya, Yamaguchi Tomohiko, Naito Yoshiki, Akiba Jun
- Organizer
  40th European Congress of Cytology
- Place of Presentation
  イギリスリバプール
- Year and Date
  2016-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460462
[Presentation] Epidermal growth factor receptor mutation status in cell-free DNA supernatant of bronchial cytology samples2016
- Author(s)
  Kawahara Akihiko, Fukumitsu Chihiro, Taira Tomoki, Abe Hideyuki, Takase Yorihiko, Murata Kazuya, Yamaguchi Tomohiko, Akiba Jun, Kage Masayoshi
- Organizer
  The 19th International Congress of Cytology (ICC2016)
- Place of Presentation
  横浜
- Year and Date
  2016-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460462
[Presentation] Detection of activating EGFR mutation status using cytology cell free DNA in supernatant from liquid-based cytology of bronchial washing and bronchial brushing samples.2015
- Author(s)
  Kawahara Akihiko, Fukumitsu Chihiro, Taira Tomoki, Abe Hideyuki, Takase Yorihiko, Murata Kazuya, Yamaguchi Tomohiko, Tanikawa Ken and Masayoshi Kage.
- Organizer
  39th European Congress of Cytology.
- Place of Presentation
  Italy, Milan.
- Year and Date
  2015-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460462
[Presentation] LBCの導入効果と分子病理診断への可能性2014
- Author(s)
  河原明彦
- Organizer
  第28回関東臨床細胞学会
- Place of Presentation
  静岡県沼津市
- Year and Date
  2014-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-26460462
[Presentation] Y-box結合タンパク(YB-1)はヒト胃癌においてHER2/ErbB2発現とラパチニブの感受性を制御する2013
- Author(s)
  柴田智博，菅　仁史，村上雄一，渡　公祐，河原明彦，鹿毛政義，和泉弘人，桑野信彦，小野眞弓．
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 腫瘍性筋上皮細胞が関与する唾液腺腫瘍の診断アプローチ．第52回2013
- Author(s)
  12. 河原明彦，原田博史，多比良朋希，山口知彦，安部秀幸，吉田友子，髙瀨頼妃呼，福満千容，秋葉　純，鹿毛政義．
- Organizer
  第52回日本臨床細胞学会秋期大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] NDRG1 deficiency suppresses tumor angiogenesis through interference of macrophage activation.2013
- Author(s)
  Kosuke Watari, Hiroshi Nabeshima, Yuichi Fukunaga, TomohiroShibata , Ai Shinoda, Akihiko Kawahara, Yuichi Murakami, Masayoshi Kage, Michihiko Kuwano, Mayumi Ono.
- Organizer
  72th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Integrin beta1/Src/Akt-driven Bypass Signaling Pathway confers EGFR-TKI Resistance in Lung Cancer Cells2013
- Author(s)
  Mayumi Ono, Rina Kanda, Kosuke Watari, Kahori Sonoda, Masashi, Maeda, Yuichi Murakami, Akihiko Kawahara, Masayoshi Kage, Hidetaka Uramoto, Michihiko Kuwano
- Organizer
  72th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Claudin-1 is detection marker of squamoid corpuscles in pancreatoblastoma.2013
- Author(s)
  Tomoki Taira, Akihiko Kawahara, Tomohiko Yamaguchi, Hideyuki Abe, Tomoko Yoshida, Yorihiko Takase, Chihiro Fukumitsu, Jun Akiba, Kage Masayoshi.
- Organizer
  The 12th Korea-Japan Joint Meeting for Diagnostic Cytopathology.
- Place of Presentation
  Korea
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 中間型松果体実質腫瘍の1例．2013
- Author(s)
  安部秀幸，河原明彦，杉田保雄，山口知彦，多比良朋希，吉田友子，髙瀨頼妃呼，福満千容，鹿毛政義．
- Organizer
  第29回日本臨床細胞学会福岡県支部総会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Integrinβ1/Akt経路活性化を介した肺癌における新規エルロチニブ耐性獲得メカニズム．2013
- Author(s)
  神田利奈，渡　公祐，河原明彦，鹿毛政義，浦本秀隆，岡本　勇，中川和彦，桑野信彦，小野眞弓．
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Integrinβ1/Akt経路活性化を介した肺癌における新規エルロチニブ耐性獲得メカニズム2013
- Author(s)
  神田利奈,渡公祐,河原明彦,鹿毛政義,浦本秀隆,岡本勇,中川和彦,桑野信彦,小野眞弓
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  京都
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] A case of EML4-ALK-positive lung adenocarcinoma with signet-ring cells2013
- Author(s)
  Akihiko Kawahara, Tomoki Taira, Tomohiko Yamaguchi, Hideyuki Abe, Tomoko Yoshida, Yorihiko Takase, Chihiro Fukumitsu, Jun Akiba, Kage Masayoshi
- Organizer
  The 12^<th > Korea-Japan Joint Meeting for Diagnostic Cytopathology
- Place of Presentation
  韓国
- Year and Date
  2013-09-07
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] IL-1α-driven AP-1 (Jun /Fos) activation plays a key role in inflammatory angiogenesis by NDRG1 in gastric cancer.2013
- Author(s)
  Yuichi Murakami, Kosuke Watari, Tomohiro Shibata, Hiroki Ureshino, Akihiko Kawahara, Masayoshi Kage, Hiroto Izumi, Michihiko Kuwano, Mayumi Ono.
- Organizer
  72th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] A case of EML4-ALK-positive lung adenocarcinoma with signet-ring cells.2013
- Author(s)
  Akihiko Kawahara, Tomoki Taira, Tomohiko Yamaguchi, Hideyuki Abe, Tomoko Yoshida, Yorihiko Takase, Chihiro Fukumitsu, Jun Akiba, Kage Masayoshi.
- Organizer
  The 12th Korea-Japan Joint Meeting for Diagnostic Cytopathology.
- Place of Presentation
  Korea
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 唾液腺領域における良性腫瘍を悪性と診断しない鑑別ポイント．2013
- Author(s)
  河原明彦，原田博史，山口知彦，安倍秀幸，多比良朋希，髙瀨頼妃呼，福満千容，谷川　健，　秋葉　純，鹿毛政義
- Organizer
  第54回日本臨床細胞学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Integrin beta1/Src/Akt-driven Bypass Signaling Pathway confers EGFR-TKI Resistance in Lung Cancer Cells.2013
- Author(s)
  Mayumi Ono, Rina Kanda, Kosuke Watari, Kahori Sonoda, Masashi, Maeda, Yuichi Murakami, Akihiko Kawahara, Masayoshi Kage, Hidetaka Uramoto, Michihiko Kuwano.
- Organizer
  72th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] ワルチン腫瘍と粘表皮癌におけるp63の発現比較．2013
- Author(s)
  高橋瑞恵，河原明彦，佐藤真介，宮崎浩子，横地康輔，中島明彦．
- Organizer
  第52回日本臨床細胞学会秋期大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 細胞診による子宮内膜癌のtype分類の検討．2013
- Author(s)
  山口知彦，河原明彦，多比良朋希，安部秀幸，吉田友子，真田咲子，秋葉　純，牛島公生，嘉村敏治，鹿毛政義
- Organizer
  第54回日本臨床細胞学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] LBCを用いた気管支擦過細胞診の現状.肺癌治療における細胞診の役割2013
- Author(s)
  河原明彦
- Organizer
  中四国実践セミナー
- Place of Presentation
  愛媛
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 液状気管支細胞診を用いた肺癌診断．2013
- Author(s)
  福満千容，河原明彦，多比良朋希，山口知彦，安倍秀幸，吉田友子，髙瀨頼妃呼，秋葉　純，谷川　健，鹿毛政義．
- Organizer
  第54回日本臨床細胞学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 液状気管支細胞診を用いた肺癌診断2013
- Author(s)
  福満千容,河原明彦,多比良朋希,山口知彦,安倍秀幸,吉田友子,髙瀨頼妃呼,秋葉純,谷川健,鹿毛政義
- Organizer
  第54回日本臨床細胞学会総会
- Place of Presentation
  東京
- Year and Date
  2013-06-02
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Glucose transporter-1(GLUT-1) expression in endometrial lesions.2013
- Author(s)
  Tomohiko YAMAGUCHI, Akihiko KAWAHARA, Tomoki TAIRA, Hideyuki ABE, Yoshiki NAITO, Sakiko SANADA, Shunichiro OTA, Kimio USHIJIMA, Toshiharu KAMURA, Masayoshi KAGE.
- Organizer
  18th International Congress of Cytology
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Interleukin 1 promotes lymph node metastasis by lung cancer cells through modification of tumor stroma cells2012
- Author(s)
  Tomohiro Shibata, Kosuke Watari, Akihiko Kawahara, Yuichi Murakami, Hiroshi Nabeshima, Koichi Azuma, Masayoshi Kage, Naofumi Mukaida, Michihiko Kuwano, Takashi Takahashi, Mayumi Ono
- Organizer
  71th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  71th Annual Meeting of the Japanese Cancer Association
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 液状検体における細胞診の役割と遺伝子診断2012
- Author(s)
  河原明彦,多比良朋希,山口知彦,安倍秀幸,吉田友子,髙瀨頼妃呼,福満千容,秋葉純,鹿毛政義
- Organizer
  第51回日本臨床細胞学会秋期大会
- Place of Presentation
  新潟
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 液状検体における細胞診の役割と遺伝子診断．2012
- Author(s)
  河原明彦，多比良朋希，山口知彦，安倍秀幸，吉田友子，髙瀨頼妃呼，福満千容，秋葉　純，　鹿毛政義．
- Organizer
  第51回日本臨床細胞学会秋期大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid2012
- Author(s)
  Kawahara Akihiko
- Organizer
  37^<th> European Congress of Cytology
- Place of Presentation
  Croatia, Dubrovnik
- Year and Date
  2012-09-30
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] A novel mechanism for acquired resistance to EGFR-TKI in human lung cancer : loss of activating mutant EGFR gene allele2012
- Author(s)
  Rina Kanda, Yuichi Murakami, Akihiko Kawahara, Koichi Azuma, Masayoshi Kage, Tomoko Tahira, Michihiko Kuwano, Mayumi Ono
- Organizer
  71th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Hokkaido
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 液状細胞診にて診断した気管支原発粘表皮癌の1例2012
- Author(s)
  福満千容,河原明彦,山口知彦,安倍秀幸,多比良朋希,吉田友子,髙瀨頼妃呼,秋葉純,鹿毛政義
- Organizer
  第51回日本臨床細胞学会秋期大会
- Place of Presentation
  新潟
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Characteristics of immunohistochemical ALK-positive lung cancer2012
- Author(s)
  Jun Akiba, Akihiko Kawahara, Masayoshi Kage, Hirohisa Yano
- Organizer
  71th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Hokkaido
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] ワークショップ.肺癌患者の診断と治療における呼吸器細胞診の役割2011
- Author(s)
  河原明彦,多比良朋希,安部秀幸,山口知彦,吉田友子,秋葉純,鹿毛政義
- Organizer
  第50回日本臨床細胞学会秋期大会
- Place of Presentation
  東京
- Year and Date
  2011-10-23
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 肺癌患者の診断と治療における呼吸器細胞診の役割.2011
- Author(s)
  河原明彦.
- Organizer
  第50回日本臨床細胞学会秋期大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Immunocytochemical diagnosis of activating EGFR mutations in NSCLC using mutation-specific antibodies2011
- Author(s)
  Kawahara Akihiko, Koichi Azuma, Kuwano Michihiko, Masayoshi Kage, Mayumi Ono
- Organizer
  70^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] Immunocytochemical diagnosis of activating EGFR mutations in NSCLC using mutation-specific antibodies.2011
- Author(s)
  Akihiko Kawahara.
- Organizer
  70th Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] 再発肺癌細胞におけるEGFR遺伝子変異の免疫細胞化学による検出2011
- Author(s)
  河原明彦,山口知彦,安倍秀幸,多比良朋希,吉田友子,内藤嘉紀,秋葉純,鹿毛政義
- Organizer
  第52回日本臨床細胞学会総会
- Place of Presentation
  福岡
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23790425
[Presentation] EGFR遺伝子変異特異的抗体を用いたSurePath細胞保存液の固定効果
- Author(s)
  河原明彦，多比良朋希，安倍秀幸，山口知彦，吉田友子，髙瀨頼妃呼，福満千容，谷川　健，秋葉　純，鹿毛政義
- Organizer
  第55回日本臨床細胞学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26460462
[Presentation] Fixation effect of SurePath preservative fluids using EGFR mutation-specific antibodies for immunocytochemistry
- Author(s)
  Kawahara Akihiko, Taira Tomoki, Abe Hideyuki, Fukumitsu Chihiro, Takase Yorihiko, Yamaguchi Tomohiko, Akiba Jun, Masayoshi Kage
- Organizer
  38th European Congress of Cytology
- Place of Presentation
  Switzerland, Geneva
- Year and Date
  2014-09-27 – 2014-09-30
- Data Source
  KAKENHI-PROJECT-26460462

1. KAIDA HAYATO (40299425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 服部聡 (50425154)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 石井一成 (50534103)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 伊藤彰彦 (80273647)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. FUJIMOTO Kiminori (00199366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. TONAN Tatsuyuki (40268892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. KAWAGUCHI Atsushi (60389319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HAYABUCHI Naofumi (20108731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 加藤天美 (00233776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 村上卓道 (20252653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 安田卓司 (10324782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 細野眞 (00281303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 村上雄一 (60464385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 松本太一 (80570803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 肥川和寛 (50941308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 轟圭太 (60624434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 秋葉純 (00341305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 安陪由思 (50748712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 植田浩介 (60569440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 中山正道 (80795229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 主藤朝也 (50309803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 内藤嘉紀 (50465712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KAGE Masayoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 岩熊伸高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 笹田哲朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
26. 小野真弓

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
27. 山田亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAHARA Akihiro 河原 明彦

Research Projects

Research Products

Co-Researchers

Development of novel therapeutic approach for ovarian clear cell carcinoma targeting cell cycle regulation by A.

Principal Investigator

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Development of novel chemotherapy to selectively induce ferroptosis in pancreatic cancer cells by targeting ALOX12

Principal Investigator

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口腔癌の癌幹細胞と周囲微小環境とのクロストーク機構解析による新規治療戦略の確立

Principal Investigator

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食道癌のTIME自動診断のプラットフォーム開発に関する研究

Principal Investigator

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Review Section

Research Institution

食道癌術前化学療法の治療効果予測―低酸素イメージングと癌シグナル伝達因子との相関

Principal Investigator

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Review Section

Research Institution

To elucidate the prognostic marker using amino acid PET imaging and signal transduction factors in brain tumor patients

Principal Investigator

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Research Institution

Establish of new detection method of gene mutations using cell-free DNA in supernatant fluidsPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Establish of new deteciton of EGFR mutation status using immunostaining in non-small cell lung cancerPrincipal Investigator

Principal Investigator

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Research Institution

CD14 expression and Kupffer cell dysfunction in non-alcoholic steatohepatitis : Superparamagnetic iron oxide-magnetic resonance image and pathologic correlation

Principal Investigator

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Research Institution

[Journal Article] EGFR mutation status in cell-free DNA supernatant of bronchial washings and brushings.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of immunohistochemistry using two different antibodies and procedures for primary lung adenocarcinoma harboring anaplastic lymphoma kinase rearrangement2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EML4-ALK-positive lung adenocarcinoma with signet-ring cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Humoral immune responses to EGFR-derived peptides predict progression-free and overall survival of non-small cell lung cancer patients receiving gefitinib.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor2014

Author(s)

KAWAHARA Akihiro 河原明彦