Okumura Fumihiko 奥村文彦

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OKUMURA Fumihiko 奥村文彦

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Researcher Number	00507212
Other IDs
Affiliation (Current)	2025: 福岡女子大学, 国際文理学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 福岡女子大学, 国際文理学部, 准教授 2019 – 2023: 福岡女子大学, 国際文理学部, 准教授 2016 – 2018: 名古屋大学, 理学研究科, 講師 2015: 名古屋大学, 大学院理学研究科, 助教 2011 – 2015: 名古屋大学, 理学(系)研究科(研究院), 助教 … More 2009 – 2011: Hokkaido University, 大学院・医学研究科, 助教 2009: 北大, 医学(系)研究科(研究院), 助教 2008: Hokkaido University, 医学(系)研究科(研究院), 助教 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 59040:Nutrition science and health science-related / Basic Section 44010:Cell biology-related / Biological pharmacy / Biological Sciences / Boundary agriculture Except Principal Investigator Functional biochemistry / Pathological medical chemistry
Keywords	Principal Investigator ユビキチン / タンパク質分解 / タンパク質翻訳 / ISG15 / 細胞分化 / 細胞周期 / 骨格筋分化 / Cdon / Cdo / ZSWIM8 … More / 筋分化 / SSB / Eph / SPSB4 / 細胞間反発運動 / EphB2 / ガン / 自然免疫 / セルラーゼ / バイオマス / バイオエタノール / インターフェロン / ユビキチン様分子 / 4EHP / キャップ構造 / アメリカ / 国際情報交換 … More Except Principal Investigator タンパク質分解 / ユビキチン / 転写因子 / ストレス応答 / 蛋白質分解 / 癌 / ガン / 前立腺癌 / クロマチン / 神経発生 / 細胞周期 / アンドロゲン / 癌化 / TRIMファミリー / 分子腫瘍学 Less

ISG15修飾を介した自然免疫応答の解明とISG15修飾を亢進する栄養素の探索Principal Investigator
- Principal Investigator
  
  奥村文彦
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fukuoka Women's University
The regulation of cell division and cell differentiation by the Elongin BC-type ubiquitin ligasePrincipal Investigator
- Principal Investigator
  
  Okumura Fumihiko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Fukuoka Women's University
  Nagoya University
Elucidation of novel function of Saccharomyces cerevisiae SCF complex
- Principal Investigator
  
  Kamura Takumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
Regulation of Ephrin receptor by inducible ubiquitin ligase SSBPrincipal Investigator
- Principal Investigator
  
  Okumura Fumihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Functiona analysis of tumor suppressor gene product pVHL
- Principal Investigator
  
  Kamura Takumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
Regulation of intercellular crosstalk by induced ubiquitin ligase SSBPrincipal Investigator
- Principal Investigator
  
  FUMIHIKO Okumura
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
ユビキチン様分子ＩＳＧ１５依存性タンパク質翻訳制御と自然免疫応答の関連性の解析Principal Investigator
- Principal Investigator
  
  奥村文彦
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Comprehensive analysis of the regulation of carcinogenesis through TRIM type ubiquitin ligases
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University
ヒト培養細胞を使ったバイオマス変換酵素の効率的産生システムの開発Principal Investigator
- Principal Investigator
  
  奥村文彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Boundary agriculture
- Research Institution
  Hokkaido University
ユビキチン様分子ISG15による翻訳制御の解明Principal Investigator
- Principal Investigator
  
  奥村文彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University

[Book] 生化学
- Author(s)
  奥村文彦
- Publisher
  (財)学会誌刊行センター(印刷中)
- Data Source
  KAKENHI-PROJECT-20890004
[Journal Article] Curcumin partly prevents ISG15 activation via ubiquitin-activating enzyme E1-like protein and decreases ISGylation2022
- Author(s)
  Oki Nodoka、Yamada Shino、Tanaka Tamaki、Fukui Hiromi、Hatakeyama Shigetsugu、Okumura Fumihiko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 625 Pages: 94-101
- DOI
  10.1016/j.bbrc.2022.08.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-21H02674, KAKENHI-PUBLICLY-21H00266
[Journal Article] Triacylglycerol lipase Tgl4 is a stable protein and its dephosphorylation is regulated in a cell cycle-dependent manner in Saccharomyces cerevisiae2022
- Author(s)
  Nakatsukasa Kunio、Fujisawa Munetaka、Yang Xiaotan、Kawarasaki Tomoyuki、Okumura Fumihiko、Kamura Takumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 626 Pages: 85-91
- DOI
  10.1016/j.bbrc.2022.08.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-19H02923
[Journal Article] ユビキチンリガーゼKLHDC1によるセレノプロテインSの品質管理2022
- Author(s)
  奥村文彦、嘉村巧
- Journal Title
  
  月刊「細胞」2022年11月号　翻訳制御の最前線
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06213
[Journal Article] KLHDC1による不良SELENOSの除去2021
- Author(s)
  奥村文彦・嘉村巧
- Journal Title
  
  月刊「細胞」
  
  Volume: 53（3） Pages: 28-31
- NAID
  40022520026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06213
[Journal Article] ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation2021
- Author(s)
  Okumura Fumihiko、Oki Nodoka、Fujiki Yuha、Ikuta Rio、Osaki Kana、Hamada Shun、Nakatsukasa Kunio、Hisamoto Naoki、Hara Taichi、Kamura Takumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20880-20880
- DOI
  10.1038/s41598-021-00306-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-20H03408, KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-19H02923
[Journal Article] Cul5-type Ubiquitin Ligase KLHDC1 Contributes to the Elimination of Truncated SELENOS Produced by Failed UGA/Sec Decoding2020
- Author(s)
  Okumura Fumihiko、Fujiki Yuha、Oki Nodoka、Osaki Kana、Nishikimi Akihiko、Fukui Yoshinori、Nakatsukasa Kunio、Kamura Takumi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 3 Pages: 100970-100970
- DOI
  10.1016/j.isci.2020.100970
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-19K06569, KAKENHI-PUBLICLY-19H04957, KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-19H00983, KAKENHI-PROJECT-19H02923
[Journal Article] Ubiquitin-proteasome-dependent degradation of single-pass transmembrane protein EphB22019
- Author(s)
  奥村文彦、嘉村巧
- Journal Title
  
  生化学
  
  Volume: 91 Issue: 5 Pages: 681-685
- DOI
  10.14952/SEIKAGAKU.2019.910681
- NAID
  40022059251
- ISSN
  0037-1017
- Year and Date
  2019-10-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06213
[Journal Article] ISG15 修飾2018
- Author(s)
  奥村　文彦
- Journal Title
  
  生体の科学
  
  Volume: 69（ 5 ）
- Data Source
  KAKENHI-PROJECT-18K06213
[Journal Article] The HECT-type ubiquitin ligase Tom1 contributes to the turnover of Spo12, a component of the FEAR network, in G2/M phase.2018
- Author(s)
  *Nakatsukasa K., Sone M., Alemayehu D.H., Okumura F., and *Kamura T.
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Issue: 10 Pages: 1716-1724
- DOI
  10.1002/1873-3468.13066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-17H03652
[Journal Article] The HECT-type ubiquitin ligase Tom1 contributes to the turnover of Spo12, a component of the FEAR network, in G2/M phase2018
- Author(s)
  Nakatsukasa, K., Sone, M., Alemayehu, D. H., Okumura, F., and Kamura, T.
- Journal Title
  
  FEBS letters
  
  Volume: 592 Pages: 1716-1724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06213
[Journal Article] Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation2018
- Author(s)
  Tognon, C. E., Rafn, B., Cetinbas, N. M., Kamura, T., Trigo, G., Rotblat, B., Okumura, F., Matsumoto, M., Chow, C., Davare, M., Pollak, M., Mayor, T., and Sorensen, P. H.
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 32 Pages: 12502-12515
- DOI
  10.1074/jbc.ra117.000321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011
[Journal Article] Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.2017
- Author(s)
  1.Okumura, F., Joo-Okumura, A., Obara, K., Petersen, A., Nishikimi, A., Fukui, Y., Nakatsukasa, K., and Kamura, T
- Journal Title
  
  Mol Biol Cell
  
  Volume: 28 Issue: 24 Pages: 3532-3541
- DOI
  10.1091/mbc.e17-07-0450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-17J40101, KAKENHI-PROJECT-15K21056
[Journal Article] Hypoxia-inducible factor-2α stabilizes the von Hippel-Lindau (VHL) disease suppressor, Myb-related protein 2.2017
- Author(s)
  Okumura F, Joo-Okumura A, Nakatsukasa K, Kamura T.
- Journal Title
  
  PLoS One
  
  Volume: 12(4):e0175593. Issue: 4 Pages: 1-10
- DOI
  10.1371/journal.pone.0175593
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21056, KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-17J40101
[Journal Article] The role of cullin 5-containing ubiquitin ligases2016
- Author(s)
  Okumura, F. , Joo-Okumura, A., Nakatsukasa, K. & Kamura, T.
- Journal Title
  
  Cell Division.
  
  Volume: N/A Issue: 1 Pages: 1-1
- DOI
  10.1186/s13008-016-0016-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21056, KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-25291023, KAKENHI-PROJECT-15K18503
[Journal Article] Parallel regulation of VHL disease by pVHL-mediated degradation of B-Myb and HIF-α2016
- Author(s)
  Okumura, F., Uematsu, K., Byrne, S.D., Hirano, M., Okumura, A. J., Nishikimi, A., Shuin, T., Fukui, Y., Nakatsukasa, K. & Kamura, T.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25291023
[Journal Article] Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.2016
- Author(s)
  Okumura F, Uematsu K, Byrne SD, Hirano M, Joo-Okumura A, Nishikimi A, Shuin T, Fukui Y, Nakatsukasa K, Kamura T.
- Journal Title
  
  Molecular Cellular Biology
  
  Volume: 36 Issue: 12 Pages: 1803-1817
- DOI
  10.1128/mcb.00067-16
- NAID
  120005844088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01330, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-13J40160, KAKENHI-PROJECT-15K14474, KAKENHI-PROJECT-15K18503, KAKENHI-PROJECT-15K21056
[Journal Article] ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.2016
- Author(s)
  Uematsu K, Okumura F, Tonogai S, Joo-Okumura A, Alemayehu DH, Nishikimi A, Fukui Y, Nakatsukasa K, Kamura T.
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 215(1) Pages: 95-106
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21056
[Journal Article] Parallel regulation of VHL disease by pVHL-mediated degradation of B-Myb and HIF-alpha2016
- Author(s)
  Okumura, F., Uematsu, K., Byrne, S.D., Hirano, M., Okumura, A. J., Nishikimi, A., Shuin, T., Fukui, Y., Nakatsukasa, K. & Kamura, T.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21056
[Journal Article] The ubiquitin ligase SCFUcc1 acts as a metabolic switch for the glyoxylate cycle.2015
- Author(s)
  Nakatsukasa, K., Nishimura, T., Byrne, D., Okamoto, M., Takahashi-Nakaguchi, A., Chibana, H., Okumura, F., Kamura, T.
- Journal Title
  
  Molecular Cell
  
  Volume: 59 Issue: 1 Pages: 22-34
- DOI
  10.1016/j.molcel.2015.04.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14474, KAKENHI-PROJECT-15K18503, KAKENHI-PROJECT-15K21056, KAKENHI-PLANNED-24112006
[Journal Article] Proteolytic regulation of metabolic enzymes by E3 ubiquitin ligase complexes: lessons from yeast.2015
- Author(s)
  Nakatsukasa, K., Okumura, F., Kamura, T
- Journal Title
  
  Crit Rev Biochem Mol Biol.
  
  Volume: 50 Issue: 6 Pages: 489-502
- DOI
  10.3109/10409238.2015.1081869
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14474, KAKENHI-PROJECT-15K18503, KAKENHI-PROJECT-15K21056, KAKENHI-PLANNED-24112006
[Journal Article] The nutrient stress-induced small GTPase Rab5 contributes to the activation of vesicle trafficking and vacuolar activity.2014
- Author(s)
  Nakatsukasa K, Kanada A, Matsuzaki M, Byrne SD, Okumura F, Kamura T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 289(30) Pages: 20970-20978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860043
[Journal Article] Activation of double-stranded RNA-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation2013
- Author(s)
  Okumura, F., Okumura, AJ., Uematsu, K., Hatakeyama, S., Zhang, DE., Kamura, T
- Journal Title
  
  J Biol Chem
  
  Volume: 288(4) Issue: 4 Pages: 2839-47
- DOI
  10.1074/jbc.m112.401851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370051, KAKENHI-PUBLICLY-23117501, KAKENHI-PROJECT-23657088, KAKENHI-PROJECT-23659144, KAKENHI-PROJECT-24390065, KAKENHI-PLANNED-24112006
[Journal Article] Regulation of cellular functions by Elongin BC based E3 ubiquitin ligase2013
- Author(s)
  奥村文彦
- Journal Title
  
  生化学（日本語総説）
  
  Volume: 85(2) Pages: 76-88
- NAID
  10031156446
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117501
[Journal Article] The Role of Elongin BC-Containing Ubiquitin Ligases.2012
- Author(s)
  Fumihiko Okumura, Mariko Matsuzaki, Kunio Nakatsukasa, Takumi Kamura
- Journal Title
  
  Regulation of cellular functions by Elongin BC based E3 ubiquitin ligase
  
  Volume: 2 Pages: 1-13
- DOI
  10.3389/fonc.2012.00010
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020017, KAKENHI-PROJECT-22370051, KAKENHI-PUBLICLY-23117501, KAKENHI-PROJECT-23657088
[Journal Article] TRIM32 promotes retinoic acid receptor alpha-mediated differentiation in human promyelogenous leukemic cell line HL602012
- Author(s)
  Sato, T., Okumura, F., Iguchi, A., Ariga, T. and Hatakeyama, S.
- Journal Title
  
  Biochem. Biophys. Res.Commun.
  
  Volume: 417 Issue: 4 Pages: 594-600
- DOI
  10.1016/j.bbamcr.2011.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-23659144
[Journal Article] TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and indices neuritogenesis2012
- Author(s)
  Yaguchi, H., Okumura, F., Takahashi, H., Kano, T., Kameda, H., Uchigashima, M., Tanaka, S., Watanabe, M., Sasaki, H. and Hatakeyama, S.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Issue: 15 Pages: 12050-12059
- DOI
  10.1074/jbc.m111.307678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-23659144, KAKENHI-PROJECT-23800001, KAKENHI-PROJECT-24659121, KAKENHI-PROJECT-24689016
[Journal Article] TRIM6 interacts with Myc and maintains the pluripotency of mouse embryonal stem cells2012
- Author(s)
  Sato, T., Okumura, F., Ariga, T. and Hatakeyama, S.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 125 Issue: 20 Pages: 1544-1555
- DOI
  10.1242/jcs.088799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-23659144
[Journal Article] TRIM8 regulates Nanog via Hsp90 beta-mediated nuclear translocation of STAT3 in embryonic stem cells2011
- Author(s)
  Okumura, F., Okumura, A.J., Matsumoto, M., Nakayama, K.I. and Hatakeyama, S.
- Journal Title
  
  BBA-Mol. Cell Res.
  
  Volume: 1813 Issue: 10 Pages: 1784-1792
- DOI
  10.1016/j.bbamcr.2011.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-22710186, KAKENHI-PROJECT-23659144
[Journal Article] MDA-9/syntenin interacts with ubiquitin via a novel ubiquitin-bindingmotif2011
- Author(s)
  Okumura, F., et al
- Journal Title
  
  Mol.Cell.Biochem.
  
  Volume: 352 Pages: 163-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] TRIM8 regulates Nanog via Hsp90β-mediated nuclear translocation of STAT3 in embryonic stem cells.2011
- Author(s)
  奥村　文彦
- Journal Title
  
  Biochim. Biophys. Acta.
  
  Volume: 1813(10) Pages: 1784-1792
- Data Source
  KAKENHI-PUBLICLY-23117501
[Journal Article] TRM40 promotes neddylation of IKK gamma and is downregulated in gastrointestinal cancers2011
- Author(s)
  Noguchi, K., Okumura, F., Takahashi, N., Kataoka, A., Kamiyama, T., Todo, S. and Hatakeyama, S.
- Journal Title
  
  Carcinogenesis
  
  Volume: 32 Issue: 7 Pages: 995-1004
- DOI
  10.1093/carcin/bgr068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-23659144
[Journal Article] RNF43 interacts with NEDL1 and regulates p53-mediated transcription2011
- Author(s)
  Shinada, K., Tsukiyama, T., Sho, T., Okumura, F., Asaka, M., Hatakeyama, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 404 Pages: 143-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] Plasma gelsolin facilitates interaction between beta 2 glycoprotein I and alpha 5 beta 1 integrin2011
- Author(s)
  Bohgaki, M., Matsumoto, M., Atsumi, T., Kondo, T., Yasuda, S., Horita, T., Nakayama, K.I., Okumura, F., *Hatakeyama, S. and Koike, T.
- Journal Title
  
  J. Cell. Mol. Med.
  
  Volume: 15 Pages: 141-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] MDA-9/synten ininteracts with ubiquitin via a novel ubiquitin binding motif2011
- Author(s)
  Okumura, F., Yoshida, K., Liang, F. and Hatakeyama, S.
- Journal Title
  
  Mol. Cell.Biochem.
  
  Volume: 352 Pages: 163-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] MDA-9/syntenin interacts with ubiquitin via a novel ubiquitin-binding motif2011
- Author(s)
  Okumura, F., et al
- Journal Title
  
  Mol.Cell.Biochem.
  
  Volume: 352 Issue: 1-2 Pages: 163-172
- DOI
  10.1007/s11010-011-0750-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-23659144
[Journal Article] TRIM8 modulates STAT3 activity through negative regulation of PIAS3.2010
- Author(s)
  Okumura F, Matsunaga Y, Katayama Y, Nakavama KI.Hatakeyama S
- Journal Title
  
  Journal of Cell Science
  
  Volume: 123(13) Pages: 2238-2245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21658110
[Journal Article] Expression of recombinant sea urchin cellulase SnEG54 using mammalian cell lines2010
- Author(s)
  Okumura, F., et al
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 395 Pages: 352-355
- NAID
  120002148680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] TRIM8 modulates STAT3 activity through negative regulation of PIAS32010
- Author(s)
  Okumura, F., Matsunaga, Y., Katayama, Y., Nakayama, K.I., Hatakeyama, S.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 123 Pages: 2238-2245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] Expression of recombinant sea urchin cellulase SnEG54 using mammalian cell lines2010
- Author(s)
  Okumura, F., Kameda, H., Ojima, T., Hatakeyama, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 395 Pages: 352-355
- NAID
  120002148680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] TRIM8 modulates STAT3 activity through negative regulation of PIAS32010
- Author(s)
  Okumura, F., et al
- Journal Title
  
  J.Cell.Sci.
  
  Volume: 123 Pages: 1138-2245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] RNF43 interacts with NEDL1 and regulates p53-mediated transcription.2010
- Author(s)
  Shinada K, Tsukiyama T, Sho T, Okumura F, Asska M, Hatakevama S
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 404(1) Pages: 143-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21658110
[Journal Article] Expression of recombinant sea urchin cellulase SnEG54 using mammalian cell lines.2010
- Author(s)
  Okumura F, Kameda H, Ojima T, Hatakeyama S
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 395(3) Pages: 352-355
- NAID
  120002148680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21658110
[Journal Article] TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells2009
- Author(s)
  Kikuchi, M., Okumura, F., Tsukiyama, T., Watanabe, M., Miyajima, N., Tanaka, J., Imamura, M., Hatakeyama, S.
- Journal Title
  
  BBA-MCR.
  
  Volume: 1793 Pages: 1828-1836
- NAID
  120001804922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article]2009
- Author(s)
  奥村文彦
- Journal Title
  
  ユビキチン様分子ISG15による免疫反応制御(社団法人日本生化学会)
  
  Pages: 223-232
- Data Source
  KAKENHI-PROJECT-21658110
[Journal Article] Ubiquitin-conjugating enzyme UBE2Q2 suppresses cell proliferation and is down-regulated in recurrent head and neck cancer2009
- Author(s)
  Maeda, H., Miyajima, N., Kano, S., Tsukiyama, T., Okumura, F., Fukuda, S. and Hatakeyama, S.
- Journal Title
  
  Mol. Cancer Res.
  
  Volume: 7 Pages: 1553-1562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt2009
- Author(s)
  Suizu. F., Hiramuki, Y., Okumura, F., Matsuda, M., Okumura, A.J., Hirata, N., Narita, M., Kohno, T., Yokota, J., Bohgaki, M., Obuse, C., Hatakeyama, S., Obata, T. and Noguchi, M
- Journal Title
  
  Dev. Cell
  
  Volume: 17 Pages: 800-810
- NAID
  120005385335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] Nitrosylation of ISG15 prevents the disulfide bond mediated dimerization of ISG15 and contributes to effective ISGylation2008
- Author(s)
  Fumihiko Okumura
- Journal Title
  
  The Journal of Biological Chemistry 5 ; 283(36)
  
  Pages: 24484-24488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890004
[Journal Article] MDA-9/syntenin interacts with ubiquitin via a novel ubiquitin-binding motif
- Author(s)
  Okumura, F., Yoshida, K., Liang, F., Hatakeyama, S.
- Journal Title
  
  Mol.Cell.Biochem.
  
  Volume: (In press,In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21658110
[Presentation] インターフェロンにより誘導されるIBPはIFITM1と結合し、特定のウイルス感染を抑制する2024
- Author(s)
  奥村文彦、仁田暁大、中山敬一、Alexander Hahn、Dong-Er Zhang
- Organizer
  日本薬学会第１４４年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] インターフェロン誘導タンパク質ISGはIFITM1と結合し、特定のウイルス感染を抑制する2023
- Author(s)
  奥村文彦、仁田暁大、中山敬一、Alexander Hahn、Dong-Er Zhang
- Organizer
  第46回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] クルクミンはISG15活性化酵素を抑制しISG15修飾を減弱する2023
- Author(s)
  奥村文彦、大木のどか、山田詩乃、田中環、福井裕美、畠山鎮次
- Organizer
  日本薬学会第143年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] インターフェロンにより誘導されるISGはIFITM1と結合し、一部リソソームに局在する2023
- Author(s)
  奥村文彦、仁田暁大、中山敬一、Alexander Hahn、Dong-Er Zhang
- Organizer
  第96回日本生化学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 香辛料はISG15活性化酵素を阻害してISG15修飾を抑制する2022
- Author(s)
  大木のどか、山田詩乃、田中環、福井裕美、畠山鎮次、奥村文彦
- Organizer
  第45回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 筋分化で誘導されるタンパク質ZSWIM8はC2C12筋芽細胞の分化を抑制する2022
- Author(s)
  奥村文彦、大木のどか、藤木結葉、生田李緒、濱田俊、中務邦雄、久本直毅、原太一、嘉村巧
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 香辛料によるISG15修飾の抑制2022
- Author(s)
  大木のどか、山田詩乃、田中環、福井裕美、畠山鎮次、奥村文彦
- Organizer
  第95回日本生化学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 必須微量元素セレンによる小胞体ストレス応答タンパク質SELENOSの安定化2021
- Author(s)
  奥村文彦, 藤木結葉, 大木のどか, 尾崎加奈, 錦見昭彦, 福井宣規, 中務邦雄, 嘉村巧
- Organizer
  日本薬学会第141年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] SELENOSはセレノシステイン取り込みにより安定化する2021
- Author(s)
  奥村文彦，藤木結葉，大木のどか，尾崎加奈，錦見昭彦，福井宣規，中務邦雄，嘉村巧
- Organizer
  生命金属に関する合同年会（ConMetal 2020）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] Cul2結合タンパク質ZSWIM8はC2C12筋芽細胞の分化を抑制する2021
- Author(s)
  奥村文彦、大木のどか、藤木結葉、生田李緒、濱田俊、中務邦雄、久本直毅、原太一、嘉村巧
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] Cul2結合タンパク質ZSWIM8はC2C12筋芽細胞分化に伴い発現誘導される2021
- Author(s)
  奥村文彦、大木のどか、藤木結葉、生田李緒、濱田俊、中務邦雄、久本直毅、原太一、嘉村巧
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] ユビキチンリガーゼKLHDC1によるSELENOSの品質管理と小胞体ストレスの蓄積2021
- Author(s)
  奥村文彦、藤木結葉、大木のどか、尾崎加奈、錦見昭彦、福井宣規、中務邦雄、嘉村巧
- Organizer
  第43回日本分子生物学会年会 (MBSJ2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] ユビキチンリガーゼKLHDC1は不完全なSELENOSを除去する2021
- Author(s)
  奥村文彦
- Organizer
  第93回日本生化学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 低酸素応答因子HIF-2alphaはVHL病抑制因子B-Mybを安定化する2020
- Author(s)
  奥村文彦、藤木結葉、大木のどか、尾﨑加奈、中務邦雄、嘉村巧
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] ＨＩＦ-２alphaによるフォン・ヒッペル・リンドウ病抑制因子Ｂ－Ｍｙｂの安定化2019
- Author(s)
  奥村文彦, 奥村晶子, 中務邦雄, 嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母のストレス応答因子Wta1の制御機構の解析2019
- Author(s)
  渡邉祥太郎, 小原圭介, 奥村文彦, 嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] HIF-2alphaによるフォン・ヒッペル・リンドウ病抑制因子B-Mybの安定化2019
- Author(s)
  奥村文彦、奥村晶子、中務邦雄、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 出芽酵母転写抑制因子Mtt24の分解制御機構2019
- Author(s)
  森田敏基、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] アダプタータンパク質Mmr1の選択的分解によるミトコンドリアの局在制御機構2019
- Author(s)
  吉川拓, 小原圭介, 奥村文彦, 嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 飢餓状態におけるRrn3の分解制御機構の解析2019
- Author(s)
  酒井洋二, 小原圭介, 奥村文彦, 嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] アダプタータンパク質 Mmr1の選択的分解によるミトコンドリアの局在制御機構2019
- Author(s)
  吉川拓、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 飢餓状態におけるRrn3の分解制御機構の解析2019
- Author(s)
  酒井洋二、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] セレン（Se）によるユビキチン化抑制と小胞体ストレス応答効率化メカニズムの解明2019
- Author(s)
  奥村　文彦
- Organizer
  第2回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 出芽酵母転写抑制因子Mtt24の分解制御機構2019
- Author(s)
  森田敏基, 小原圭介, 奥村文彦, 嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母のストレス応答因子 Wta1の制御機構の解析2019
- Author(s)
  渡邉祥太郎、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 出芽酵母のストレス応答因子Wta1の制御機構の解析2018
- Author(s)
  渡邉祥太郎, 小原圭介, 奥村文彦, 嘉村巧
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母E3リガーゼ複合体SCFMet30によるAry34の分解制御2018
- Author(s)
  山口竜, 小原圭介, 奥村文彦, 嘉村巧, 中務邦雄
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] ユビキチンリガーゼSPSB4はEphB2を介した細胞間反発運動を抑制する2018
- Author(s)
  奥村文彦、奥村（城尾）晶子、小原圭介、Alexander Petersen、錦見昭彦、福井宣規、中務邦雄、嘉村巧
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 出芽酵母ブロモドメインタンパク質Bdf2の機能解析2018
- Author(s)
  小林恵里花, 小原圭介, 大谷悠貴, 奥村文彦, 嘉村巧
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母におけるキチン合成酵素Chs2のE3リガーゼの同定2018
- Author(s)
  小林周平, 小原圭介, 奥村文彦, 嘉村巧
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母E3リガーゼSCFMet30によるAry34の分解制御機構の解析2017
- Author(s)
  山口竜、中務邦雄、奥村文彦、小原圭介、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] ユビキチンリガーゼASB7によるDDA3の発現制御は、適切な紡錘体形成と染色体分配に必要である2017
- Author(s)
  奥村文彦、植松桂司、外海駿輔、奥村(城尾) 晶子、Alemayehu Dawit、錦見昭彦、福井宣規、中務邦雄、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] Hxk2リン酸化酵素Tsk1はプロテアソーム依存的に分解される2017
- Author(s)
  田邉理志、奥村文彦、小原圭介、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] リボソーム生合成を負に制御するDot6とTod6は飢餓条件においてプロテアソーム依存的に分解される2017
- Author(s)
  鈴木優太、中務邦雄、小原圭介、奥村文彦、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] pVHL 依存的なB-Myb とHIF αの分解はそれぞれ独立してVHL 病を制御している2017
- Author(s)
  奥村文彦, 植松桂司, Byrne STUART D., 平野みえ, 奥村( 城尾) 晶子, 錦見昭彦, 執印太郎, 福井宣規, 中務邦雄, 嘉村巧
- Organizer
  日本薬学会第１３７年会
- Place of Presentation
  東北大学
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K21056
[Presentation] 出芽酵母におけるキチン合成酵素Chs2のE3リガーゼの同定2017
- Author(s)
  小林周平、奥村文彦、小原圭介、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母トリアシルグリセロールリパーゼの制御メカニズムの解析2017
- Author(s)
  藤澤宗隆、中務邦雄、小原圭介、奥村文彦、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] ユビキチンリガーゼASB7によるDDA3の発現制御は適切な紡錘体形成と染色体分配に必要である2016
- Author(s)
  奥村文彦, 植松桂司, 外海駿輔, 奥村（城尾）晶子, Dawit Hailu Alemayehu, 錦見昭彦, 福井宣規, 中務邦雄, 嘉村巧
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K21056
[Presentation] pVHL依存的なFOBとHIFαの分解はそれぞれ独立してVHL病を制御している2015
- Author(s)
  1.奥村文彦, 植松桂司, Stuart D. Byrne, 平野みえ, 奥村(城尾) 晶子, 錦見昭彦, 執印太郎, 福井宣規, 中務邦雄, 嘉村巧
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K21056
[Presentation] 染色体安定性の維持におけるCRL5ASB7ユビキチンリガーゼの機能2015
- Author(s)
  植松桂司、奥村文彦、中務邦雄、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] pVHL依存的なFOBとHIFαの分解はそれぞれ独立してVHL病を制御している2015
- Author(s)
  奥村文彦、植松桂司、Stuart D. Byrne、平野みえ、奥村(城尾) 晶子、錦見昭彦、執印太郎、福井宣規、中務邦雄、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] 出芽酵母E3リガーゼSCFDia2の新奇基質Prl1の同定2015
- Author(s)
  Dawit Hailu Alemayehu、中務邦雄、奥村文彦、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] ユビキチンリガーゼSCFMet30の新規基質p17の同定と機能解析2015
- Author(s)
  富澤優貴、中務邦雄、奥村文彦、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] Hect型E3リガーゼTom1によるFEARネットワーク構成因子Spol2の分解制御2015
- Author(s)
  栗田英奈、中務邦雄、曽根恵、奥村文彦、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] pVHLはFOBとHIF-αの分解を介してVHL病を制御する2014
- Author(s)
  1.奥村文彦, 植松桂司, 松崎真理子, 平野みえ, 奥村晶子, 錦見昭彦, 金森正和, 執印太郎, 福井宣規, 中務邦雄, 嘉村巧
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25860043
[Presentation] 複合体型ユビキチンリガーゼECSASB7の機能解2013
- Author(s)
  外海駿輔、奥村文彦、中務邦雄、嘉村巧
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] Activation of PKR by ubiquitin-like molecule ISG15 modification down-regulates protein translation.2013
- Author(s)
  Fumihiko Okumura
- Organizer
  The 35th Naito Conference "The Ubiquitin-Proteasome System: From Basic Mechanism to Pathophysiological Roles"
- Place of Presentation
  Chateraise Gateaux Kingdom Sapporo (Sapporo)
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] Regulation of protein translation by ISG15-modified PKR2013
- Author(s)
  奥村文彦，奥村晶子，植松桂司，畠山鎮次，Dong-er Zhang，嘉村巧
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25860043
[Presentation] CRL2Zyg11B複合体の新規基質p50の同定2013
- Author(s)
  松崎真理子、奥村文彦、中務邦雄、嘉村巧
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] Activation of PKR by ubiquitin-like molecule ISG15 modification down-regulates protein translation2013
- Author(s)
  Fumihiko Okumura
- Organizer
  The Ubiquitin-Proteasome System: From Basic Mechanisms to Pathophysiological Roles
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-25860043
[Presentation] 複合体型ユビキチンリガーゼECVZYG11Bの機能解析2013
- Author(s)
  植松桂司、奥村文彦、中務邦雄、嘉村巧
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] 出芽酵母FEARネットワーク構成因子Spo12の新たな分解制御機構の解明2013
- Author(s)
  曽根惠、中務邦雄、奥村文彦、嘉村巧
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] ISG15修飾を受けたPKRによるタンパク質翻訳制御2013
- Author(s)
  奥村文彦、奥村晶子、植松桂司、畠山鎮次、D. Zhang、嘉村巧
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-25291023
[Presentation] TRIM8 regulates Nanog via Hsp90β-medicated nuclear translocation of STAT3 in embryonic stem cells.2011
- Author(s)
  奥村　文彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PUBLICLY-23117501
[Presentation] TRIM8 modulates STAT3 activity through negative regulation of PIAS3.2010
- Author(s)
  Okumura F, Matsunaga Y, Katayama Y, Nakayama KI, Hatakeyama S
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21658110
[Presentation] Nitric-oxide modification(Nitrosylation)of ISG15 contributes to effective ISG15 modification(ISGylation).2009
- Author(s)
  奥村文彦
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21658110
[Presentation] メッセンジャーRNAキャップ構造結合分子eIF4E1ホモログ4EHPはユビキチン様分子ISG15修飾によりキャップ構造結合活性が増強される2008
- Author(s)
  奥村文彦
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20890004
[Presentation] ユビキチン様分子ISG15依存性翻訳制御による免疫制御の解明2008
- Author(s)
  奥村文彦
- Organizer
  日本生化学会北海道支部第45回例会
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-20890004
[Presentation] Activation of double-stranded RNA-activated protein kinase (PKR) by interferon stimulated gene 15 (ISG15) modification down-regulates cap structuredependent translation
- Author(s)
  奥村文彦
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PUBLICLY-23117501
[Presentation] Activation of double-stranded RNA-activated protein kinase (PKR) by interferon stimulated　gene 15 (ISG15) modification down-regulates cap-dependent translation
- Author(s)
  奥村文彦
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京大学医科学研究所（東京都）
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117501
[Presentation] pVHLはFOBとHIF-の分解を介してVHL病を制御する.
- Author(s)
  奥村文彦、植松桂司、松崎真理子、平野みえ、奥村晶子、錦見昭彦、金森正和、執印太郎、福井宣規、中務邦雄、嘉村巧
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25291023

1. Kamura Takumi (40333455)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
2. HATAKEYAMA Shigetsugu (70294973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. TSUKIYAMA Tadasuke (20399819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 中務邦雄 (90547522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. 原太一 (00392374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 錦見昭彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okumura Fumihiko 奥村 文彦

OKUMURA Fumihiko 奥村 文彦

Research Projects

Research Products

Co-Researchers

ISG15修飾を介した自然免疫応答の解明とISG15修飾を亢進する栄養素の探索Principal Investigator

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The regulation of cell division and cell differentiation by the Elongin BC-type ubiquitin ligasePrincipal Investigator

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Elucidation of novel function of Saccharomyces cerevisiae SCF complex

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Regulation of Ephrin receptor by inducible ubiquitin ligase SSBPrincipal Investigator

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Functiona analysis of tumor suppressor gene product pVHL

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Regulation of intercellular crosstalk by induced ubiquitin ligase SSBPrincipal Investigator

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ユビキチン様分子ＩＳＧ１５依存性タンパク質翻訳制御と自然免疫応答の関連性の解析Principal Investigator

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Comprehensive analysis of the regulation of carcinogenesis through TRIM type ubiquitin ligases

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ヒト培養細胞を使ったバイオマス変換酵素の効率的産生システムの開発Principal Investigator

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ユビキチン様分子ISG15による翻訳制御の解明Principal Investigator

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[Book] 生化学

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[Journal Article] Curcumin partly prevents ISG15 activation via ubiquitin-activating enzyme E1-like protein and decreases ISGylation2022

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[Journal Article] Triacylglycerol lipase Tgl4 is a stable protein and its dephosphorylation is regulated in a cell cycle-dependent manner in Saccharomyces cerevisiae2022

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[Journal Article] ユビキチンリガーゼKLHDC1によるセレノプロテインSの品質管理2022

Okumura Fumihiko 奥村文彦

OKUMURA Fumihiko 奥村文彦