NISHIO Hisanori 西尾壽乘

… Alternative Names

西尾壽乗ニシオヒサノリ

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Researcher Number	00507783
Affiliation (based on the past Project Information) *help	2013 – 2018: 九州大学, 大学病院, 助教 2012: 九州大学, 大学病院, 学術研究員 2012: 九州大学, 大学病院, 研究員 2010 – 2011: 九州大学, 大学院・医学研究院, 客員助教 2008: 九州大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Embryonic/Neonatal medicine
Keywords	Principal Investigator 自然免疫 / 川崎病 / オートファジー / Nod-like receptor / 動脈硬化 / 冠動脈炎 / 小児循環器学 Except Principal Investigator 自然免疫 / 血管炎 / 川崎病 … More / 免疫学 / マススペクトロメトリー / IgA血管炎 / 病原体関連分子パターン / ＰＡＭＰｓ / 冠動脈病変 / 川崎病特異物質 / 液体クロマトグラフィー質量分析法 / PAMPs / 予防医学 / 感染症学 / ヘルパーＴ細胞 / メモリーＢ細胞 / 免疫応答低下 / 結合型肺炎球菌ワクチン / 免疫不全 / NOD1 / 自然免疫受容体 / 子宮内発育遅延 / 周産期 / Nod1 / 子宮内胎児死亡 / 子宮内胎児発育遅延 / 遺伝子治療 / sFlt-1 / VEGF / CAWS / 川崎病マウスモデル / 冠動脈炎 / 膠原病学 / アレルギー / 小児免疫 Less

The mechanism of mTOR inhibitors in the treatment of Kasasaki-disease model.Principal Investigator
- Principal Investigator
  
  Nishio Hisanori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
Analysis of the mechanism in Nod1 ligand induced coronary arteritis
- Principal Investigator
  
  Tanaka Tamami
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
Development of a new therapy through the clarification of innate immune receptor for PAMPs in children with vasculitis
- Principal Investigator
  
  Hara Toshiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Fukuoka Children’s Hospital
  Kyushu University
Analysis of the factor of low immune responses to pneumococcal conjugate vaccine and Hemophilus influenzae type b conjugate vaccine in immunocompromised children
- Principal Investigator
  
  HOSHINA Takayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Occupational and Environmental Health, Japan
Analysis of autophagy in Nod1 ligand-induced coronary arteritis like Kawasaki diseasePrincipal Investigator
- Principal Investigator
  
  Nishio Hisanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
Analysis of the innate immune receptor NOD1 and its ligands as a novel cause for the development of the intrauterine fetal growth restriction
- Principal Investigator
  
  HARA TOSHIRO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyushu University
The pathophysiology of NLR ligand-induced coronary arteritis like Kawasaki diseasePrincipal Investigator
- Principal Investigator
  
  NISHIO Hisanori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
Analysis of gene therapy for coronary arteritis in Kawasaki disease in vivo
- Principal Investigator
  
  MUNEUCHI Jun
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University

All 2017 2016 2015 2014 2013 2012 2011 2010 2007

All Journal Article Presentation Patent

[Journal Article] 川崎病の動物モデル2017
- Author(s)
  西尾壽乘、名西悦郎、原寿郎、大賀正一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 68 Pages: 629-635
- Data Source
  KAKENHI-PROJECT-15K09692
[Journal Article] Clarithromycin Plus Intravenous Immunoglobulin Therapy Can Reduce the Relapse Rate of Kawasaki Disease: A Phase 2, Open-Label, Randomized Control Study.2017
- Author(s)
  Nanishi E, Nishio H, Takada H, Yamamura K, Fukazawa M, Furuno K, Mizuno Y, Saigo K, Kadoya R, Ohbuchi N, Onoe Y, Yamashita H, Nakayama H, Hara T, Ohno T, Takahashi Y, Hatae K, Harada T, Shimose T, Kishimoto J, Ohga S, Hara T.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 6 Issue: 7
- DOI
  10.1161/jaha.116.005370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04877, KAKENHI-PROJECT-15K09655
[Journal Article] Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease2017
- Author(s)
  Murata K.、Motomura Y.、Tanaka T.、Kanno S.、Yano T.、Onimaru M.、Shimoyama A.、Nishio H.、Sakai Y.、Oh-Hora M.、Hara H.、Fukase K.、Takada H.、Masuda S.、Ohga S.、Yamasaki S.、Hara T.
- Journal Title
  
  Clinical & Experimental Immunology
  
  Volume: 190 Issue: 1 Pages: 54-67
- DOI
  10.1111/cei.13002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01914, KAKENHI-PLANNED-15H05836, KAKENHI-PROJECT-16H01885, KAKENHI-PROJECT-15H04666, KAKENHI-PROJECT-15H04877, KAKENHI-PROJECT-15K09655, KAKENHI-PROJECT-16K19652, KAKENHI-PLANNED-26110009
[Journal Article] Kawasaki disease: a matter of innate immunity.2016
- Author(s)
  Hara T, Nakashima Y, Sakai Y, Nishio H, Motomura Y, Yamasaki S
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 186 Pages: 134-143
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04877
[Journal Article] Memory B-ｃell ｐools ｐredict the immune response to pneumococcal conjugate vaccine in immunocompromised children2016
- Author(s)
  Takayuki Hoshina, Shouichi Ohga, Junko Fujiyoshi, Etsuro Nanishi, Tomoko Takimoto, Shunsuke Kanno, Hisanori Nishio, Mitsumasa Saito, Yukihiko Akeda, Kazunori Oishi, Toshiro Hara
- Journal Title
  
  Journal of Infectious Diseases
  
  Volume: 213 Issue: 5 Pages: 848-855
- DOI
  10.1093/infdis/jiv469
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461598
[Journal Article] Identification of Pathogenic Cardiac CD11c+ Macrophages in Nod1-Mediated Acute Coronary Arteritis.2015
- Author(s)
  Motomura Y, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 35 Issue: 6 Pages: 1423-33
- DOI
  10.1161/atvbaha.114.304846
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09692, KAKENHI-PLANNED-26110006, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-15H04877, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-25461623
[Journal Article] The utility of biomarkers in differentiating bacterial from non-bacterial lower respiratory tract infection in hospitalized children: difference of the diagnostic performance between acute pneumonia and bronchitis.2014
- Author(s)
  Hoshina T, Nanishi E, Kanno S, Nishio H, Kusuhara K, Hara T
- Journal Title
  
  J Infect Chemother
  
  Volume: 20 Issue: 10 Pages: 616-620
- DOI
  10.1016/j.jiac.2014.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591564, KAKENHI-PROJECT-25461598
[Journal Article]2011
- Author(s)
  Nishio H, et al
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(5) Pages: 1093-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591183
[Journal Article] Nod1 ligands induce site-specific vascular inflammation2011
- Author(s)
  Nishio H, Kanno S, Onoyama S, Ikeda K, Tanaka T, Kusuhara K, Fujimoto Y, Fukase K, Sueishi K, Hara T
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(5) Issue: 5 Pages: 1093-9
- DOI
  10.1161/atvbaha.110.216325
- NAID
  120005107977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590315, KAKENHI-PROJECT-22591183, KAKENHI-PROJECT-23241074, KAKENHI-PROJECT-23591559
[Patent] 川崎病の新規治療薬としてのmTOR阻害薬2015
- Inventor(s)
  西尾　壽乘、原　寿郎、名西　悦郎
- Industrial Property Rights Holder
  西尾　壽乘、原　寿郎、名西　悦郎
- Industrial Property Rights Type
  特許
- Filing Date
  2015-08-19
- Data Source
  KAKENHI-PROJECT-25461623
[Presentation] 川崎病における自然免疫の関与;Nod1リガンド誘発冠動脈炎モデルとCD11c陽性マクロファージ2017
- Author(s)
  本村良知、神野俊介、西尾壽乘、山﨑晶、原寿郎、大賀正一
- Organizer
  第37回日本川崎病学会
- Data Source
  KAKENHI-PROJECT-15K09692
[Presentation] Innate immunity-mediated vasculitis: A new pathogenic mechanism.2017
- Author(s)
  Hara T, Motomura Y, Nanishi E, Nakashima Y, Hisanori Nishio H.
- Organizer
  10th Frontiers in Immunology Research 2017 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04877
[Presentation] Nod1誘導性川崎病モデルマウスにおけるCD11ｃ陽性マクロファージの役割2016
- Author(s)
  本村良知、神野俊介、西尾壽乘、山﨑晶、原寿郎、大賀正一
- Organizer
  第36回日本川崎病学会・学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-15K09692
[Presentation] 免疫不全小児の結合型肺炎球菌ワクチンに対する免疫応答低下の要因の検討2015
- Author(s)
  保科隆之、大賀正一、名西悦郎、神野俊介、西尾壽乗、齋藤光正、原寿郎
- Organizer
  第47回日本小児感染症学会総会・学術集会
- Place of Presentation
  ザ・セレクトン福島（福島市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25461598
[Presentation] Nod1リガンド刺激による川崎病様冠動脈炎発症モデル2013
- Author(s)
  西尾壽乘
- Organizer
  第57回日本リウマチ学会
- Place of Presentation
  京都、日本
- Invited
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] Activation of an innate immune receptor, Nod1, accelerates atherogenesis in Apoe-/-mice2013
- Author(s)
  Hara T, Kanno S, Nishio H.
- Organizer
  2nd International Conference on Clinical & Cellular Immunology
- Place of Presentation
  Las Vegas, NV, USA
- Data Source
  KAKENHI-PROJECT-24659509
[Presentation] Activation of Nod1-mediated innate immunity accelerates autherogenesis2013
- Author(s)
  Kanno S, Nishio H, Sueishi K, Hara T.
- Organizer
  Frontiers in Immunology Research 2013 International Conference
- Place of Presentation
  Monte Carlo, Monaco
- Data Source
  KAKENHI-PROJECT-24659509
[Presentation] Nod1リガンド誘発川崎病類似冠動脈炎モデル2013
- Author(s)
  西尾壽乘
- Organizer
  第23回日本外来小児科学会
- Place of Presentation
  福岡、日本
- Invited
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] マウスNod1リガンド誘発冠動脈炎は様々な細菌構成物質により増悪する2012
- Author(s)
  西尾壽乘
- Organizer
  第44回日本小児感染症学会
- Place of Presentation
  北九州、日本
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] Nod1 ligand-induced coronary arteritis is enhanced by various bacterial components.2012
- Author(s)
  Nishio H
- Organizer
  2012 Pediatric Academic Societies.
- Place of Presentation
  ボストン、アメリカ
- Invited
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] A novel role of Nod1 in the vascular inflammation2012
- Author(s)
  Hara T, Nishio H
- Organizer
  World Immune Regulation Meeting
- Place of Presentation
  Davos, Switzerland
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] Nod1 ligand-induced coronary arteritis is enhanced by various bacterial components2012
- Author(s)
  Nishio H et al
- Organizer
  Pediatric Academic Societies
- Place of Presentation
  Boston, America
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] 新規自然免疫リガンド誘発冠動脈炎モデルの検討2011
- Author(s)
  西尾壽乗, ら
- Organizer
  第43回日本小児感染症学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] Establishment of a coronary arteritis murine model by oral administration of pure innate immune ligands2011
- Author(s)
  Hara T, Nishio H et al
- Organizer
  10th world congress on inflammation
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] Nod-like receptor ligand誘発冠動脈炎モデルの病態について2011
- Author(s)
  西尾壽乘
- Organizer
  第113回日本小児科学会学術集会
- Place of Presentation
  盛岡市民文化ホール(盛岡)
- Year and Date
  2011-04-24
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] Novel coronary arteritis murine model induced by pure innate immune ligands2011
- Author(s)
  Nishio H et al
- Organizer
  22nd Fukuoka international symposium on pediatric/maternal-child health research
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] NLR ligands induce site-specific vascular inflammation2011
- Author(s)
  Nishio H et al
- Organizer
  2011 Pediatric Academic Societies
- Place of Presentation
  Denver, America
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] Nod1 ligands induce coronary arteritis2011
- Author(s)
  Hara T, Nishio H et al
- Organizer
  6th European meeting for vascular biology & medicine
- Place of Presentation
  Krakow, Poland
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] 川崎病の病因解明の最前線「川崎病と自然免疫NLRについて」2010
- Author(s)
  西尾壽乘
- Organizer
  第30回日本川崎病学会学術集会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2010-10-10
- Data Source
  KAKENHI-PROJECT-22591183
[Presentation] 抗VEGF抗体、抗TNFα抗体投与によるCAWS誘発冠動脈炎の発症抑制に関する病理学的検討2007
- Author(s)
  西尾寿乗
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  石川県音楽堂、金沢市
- Year and Date
  2007-05-15
- Data Source
  KAKENHI-PROJECT-19790732

1. YAMAMURA Kenichiro (30532858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NAGATA Hazumu (20570790)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HARA TOSHIRO (40150445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. Tanaka Tamami (60423547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MUNEUCHI Jun (60448420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HOSHINA Takayuki (30398078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. OHGA Shiouichi (60233053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. OISHI Kazunori (80160414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. NANISHI Etsuro (40624937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 池田和幸 (30507786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 神野俊介 (60725919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 本村良知 (10737175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 宮本智文 (40182050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山崎晶 (40312946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 楠原浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 居石克夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 下山敦史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NISHIO Hisanori 西尾 壽乘

西尾 壽乗 ニシオ ヒサノリ

Research Projects

Research Products

Co-Researchers

The mechanism of mTOR inhibitors in the treatment of Kasasaki-disease model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism in Nod1 ligand induced coronary arteritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new therapy through the clarification of innate immune receptor for PAMPs in children with vasculitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the factor of low immune responses to pneumococcal conjugate vaccine and Hemophilus influenzae type b conjugate vaccine in immunocompromised children

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of autophagy in Nod1 ligand-induced coronary arteritis like Kawasaki diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the innate immune receptor NOD1 and its ligands as a novel cause for the development of the intrauterine fetal growth restriction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathophysiology of NLR ligand-induced coronary arteritis like Kawasaki diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of gene therapy for coronary arteritis in Kawasaki disease in vivo

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 川崎病の動物モデル2017

Author(s)

Journal Title

Data Source

[Journal Article] Clarithromycin Plus Intravenous Immunoglobulin Therapy Can Reduce the Relapse Rate of Kawasaki Disease: A Phase 2, Open-Label, Randomized Control Study.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kawasaki disease: a matter of innate immunity.2016

Author(s)

Journal Title

Data Source

[Journal Article] Memory B-ｃell ｐools ｐredict the immune response to pneumococcal conjugate vaccine in immunocompromised children2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Pathogenic Cardiac CD11c+ Macrophages in Nod1-Mediated Acute Coronary Arteritis.2015

Author(s)

Journal Title

DOI

NISHIO Hisanori 西尾壽乘

西尾壽乗ニシオヒサノリ