Misako Nakayama 仲山美沙子

Researcher Number	00510306
Other IDs	https://orcid.org/0000-0001-8611-0662
Affiliation (based on the past Project Information) *help	2015 – 2021: 滋賀医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Experimental pathology Except Principal Investigator Experimental pathology
Keywords	Principal Investigator インフルエンザウイルス / 新型コロナウイルス / 完全分化 / 急性増悪 / 気道オルガノイド / 網羅的遺伝子発現解析 / SARS-CoV-2 / COPD / 慢性閉塞性肺疾患 / 喘息 … More / オルガノイド / 気道上皮 / 病理学 / マクロファージ / 動物モデル / TGF-β / ワクチン / 免疫反応 / カニクイザル / 長期免疫 / 潜在型TGF-β / LAP / サル / インフルエンザウイルスワクチン / 単球 / TGF-beta … More Except Principal Investigator 感染症 / ウイルス / 免疫学 / 病理学 / 次世代シーケンサー / 高病原性鳥インフルエンザ / 遺伝子多型 / ゲノム / サイトカインストーム / 霊長類モデル / インフルエンザウイルス Less

Elucidation of mechanisms involved in increased severety of influenza virus infection by using in vitro models of asthma and COPDPrincipal Investigator
- Principal Investigator
  
  Nakayama Misako
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Shiga University of Medical Science
Analysis of regulatory mechanisms of the surface expression of latent TGF-beta on monocytes and differential monocyte functions caused by the ratio of latent TGF-beta expressionPrincipal Investigator
- Principal Investigator
  
  Misako Nakayama
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science
Search for host factors in severe influenza virus infection using a nonhuman primate model
- Principal Investigator
  
  Itoh Yasushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science

All 2022 2021 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Potential Risk of Repeated Nasal Vaccination that Induces Allergic Reaction with Mucosal IgE and Airway Eosinophilic Infiltration in Cynomolgus Macaques infected with H5N1 Highly Pathogenic Avian Influenza Virus.2017
- Author(s)
  Nakayama M, Itoh Y, Shichinohe S, Nakabayashi R, Ishigaki H, Sakoda Y, Le QM, Kawaoka Y, Kida H, Ogasawara K
- Journal Title
  
  Vaccine
  
  Volume: 35 Issue: 7 Pages: 1008-1017
- DOI
  10.1016/j.vaccine.2017.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04720
[Journal Article] Comparison of pathogenicities of H7 avian influenza viruses via intranasal and conjunctival inoculation in cynomolgus macaques2016
- Author(s)
  Shichnohe S, Itoh Y, Nakayama M, Ozaki H, Soda K, Ishigaki H, Okamatsu M, Sakoda Y, Kida H, Ogasawara K
- Journal Title
  
  Virology
  
  Volume: 493 Pages: 31-38
- DOI
  10.1016/j.virol.2016.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-26850178, KAKENHI-PROJECT-15H04720
[Journal Article] Vaccination against H9N2 avian influenza virus reduces bronchus-associated lymphoid tissue formation in cynomolgus macaques after intranasal virus challenge infection2016
- Author(s)
  Nakayama M, Ozaki H, Itoh Y, Soda K, Ishigaki H, Okamatsu M, Sakoda Y, Park C-H, Tsuchiya H, Kida H, Ogasawara K
- Journal Title
  
  Pathology International
  
  Volume: 66 Issue: 12 Pages: 678-686
- DOI
  10.1111/pin.12472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-15H04720
[Journal Article] Sensitization with vaccinia virus harboring hemagglutinin recovers the immune potential against highly pathogenic H5N1 influenza virus in non-human primates2016
- Author(s)
  Fumihiko Yasui, Yasushi Itoh, Ai Ikejiri, Masahiro Kitabatake, Nobuo Sakaguchi, Keisuke Munekata, Shintaro Shichinohe, Yukiko Hayashi, Hirohito Ishigaki, Misako Nakayama, Yoshihiro Sakoda, Hiroshi Kida, Kazumasa Ogasawara, *Michinori Kohara
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 37915-37915
- DOI
  10.1038/srep37915
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01272, KAKENHI-PROJECT-15H04739, KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-26860776, KAKENHI-PROJECT-15K09532, KAKENHI-PROJECT-15K15146, KAKENHI-PROJECT-15H04720
[Journal Article] Emergence of H7N9 Influenza A Virus Resistant to Neuraminidase Inhibitors in Nonhuman Primates2015
- Author(s)
  Itoh Y, Shichinohe S, Nakayama M, Igarashi M, Ishii A, Ishigaki H, Ishida H, Kitagawa N, Sasamura T, Shiohara M, Doi M, Tsuchiya H, Nakamura S, Okamatsu M, Sakoda Y, Kida H, Ogasawara K
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 59(8) Issue: 8 Pages: 4962-4973
- DOI
  10.1128/aac.00793-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25450417, KAKENHI-PROJECT-15H04720
[Presentation] 慢性閉塞性肺疾患およびコントロール由来気道上皮におけるインフルエンザウイルス感染前後のプロテオミクス2022
- Author(s)
  M. Nakayama, J. Merl-Pham, H. Busen, A. Dmitrieva, A. Chakraborty, A. Schamberger, C. Ruppert, A. Guenther, J. Behr, A. Hilgendorff, S. Hauck, H. Adler, C. A. Staab-Weijnitz
- Organizer
  第111回日本病理学会総会(神戸)(一般講演7呼吸器1, 01-39）
- Data Source
  KAKENHI-PROJECT-20K16217
[Presentation] 慢性呼吸器疾患由来の気道上皮におけるインフルエンザウイルスと新型コロナウイルスの受容体発現解析2022
- Author(s)
  吉備沙羅、仲山美沙子、石垣宏仁、伊藤靖
- Organizer
  第111回日本病理学会総会(神戸)(学部学生ポスター 2 研究2(呼吸器・泌尿器)、PU-09）
- Data Source
  KAKENHI-PROJECT-20K16217
[Presentation] Proteomics of fully differentiated bronchial epithelial cells derived from COPD or control shows no significant differences in susceptibility or response to influenza virus infection2021
- Author(s)
  M. Nakayama, J. Merl-Pham, H. Busen, A. Dmitrieva, A. Chakraborty, A. Schamberger, C. Ruppert, A. Guenther, J. Behr, A. Hilgendorff, S. Hauck, H. Adler, C. A. Staab-Weijnitz
- Organizer
  ヨーロッパ呼吸器学会国際学会2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16217
[Presentation] 霊長類を用いた疾患モデルにおける炎症反応の解析2018
- Author(s)
  伊藤靖、石垣宏仁、仲山美沙子、小笠原一誠
- Organizer
  第107回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04720
[Presentation] サルモデルを用いた季節性インフルエンザに対する不活化全粒子ワクチンの有効性評価2018
- Author(s)
  伊藤靖、鈴木沙織、石垣宏仁、仲山美沙子、新開大史、大東卓史、野村直樹、喜田宏、小笠原一誠
- Organizer
  第22回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04720
[Presentation] Viral pneumonia caused by H5N1 highly pathogenic avian influenza virus in immunosuppressed macaques2017
- Author(s)
  Yasushi Itoh, Misako Nakayama, Hirohito Ishigaki, Kazumasa Ogasawara
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15H04720

1. Itoh Yasushi (90324566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 椎名隆 (00317744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小笠原一誠 (20169163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. 七戸新太郎 (80737148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 石垣宏仁 (90432301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. TSUCHIYA Hideaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. IGARASHI Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小原道法

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Misako Nakayama 仲山 美沙子

Research Projects

Research Products

Co-Researchers

Elucidation of mechanisms involved in increased severety of influenza virus infection by using in vitro models of asthma and COPDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of regulatory mechanisms of the surface expression of latent TGF-beta on monocytes and differential monocyte functions caused by the ratio of latent TGF-beta expressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for host factors in severe influenza virus infection using a nonhuman primate model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Potential Risk of Repeated Nasal Vaccination that Induces Allergic Reaction with Mucosal IgE and Airway Eosinophilic Infiltration in Cynomolgus Macaques infected with H5N1 Highly Pathogenic Avian Influenza Virus.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of pathogenicities of H7 avian influenza viruses via intranasal and conjunctival inoculation in cynomolgus macaques2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vaccination against H9N2 avian influenza virus reduces bronchus-associated lymphoid tissue formation in cynomolgus macaques after intranasal virus challenge infection2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sensitization with vaccinia virus harboring hemagglutinin recovers the immune potential against highly pathogenic H5N1 influenza virus in non-human primates2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Emergence of H7N9 Influenza A Virus Resistant to Neuraminidase Inhibitors in Nonhuman Primates2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 慢性閉塞性肺疾患およびコントロール由来気道上皮におけるインフルエンザウイルス感染前後のプロテオミクス2022

Author(s)

Organizer

Data Source

[Presentation] 慢性呼吸器疾患由来の気道上皮におけるインフルエンザウイルスと新型コロナウイルスの受容体発現解析2022

Author(s)

Organizer

Data Source

[Presentation] Proteomics of fully differentiated bronchial epithelial cells derived from COPD or control shows no significant differences in susceptibility or response to influenza virus infection2021

Author(s)

Organizer

Data Source

[Presentation] 霊長類を用いた疾患モデルにおける炎症反応の解析2018

Author(s)

Organizer

Data Source

[Presentation] サルモデルを用いた季節性インフルエンザに対する不活化全粒子ワクチンの有効性評価2018

Author(s)

Organizer

Data Source

[Presentation] Viral pneumonia caused by H5N1 highly pathogenic avian influenza virus in immunosuppressed macaques2017

Author(s)

Organizer

Data Source

Misako Nakayama 仲山美沙子