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Sasaki Naoto  佐々木 直人

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SASAKI Naoto  佐々木 直人

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Researcher Number 00514746
Other IDs
Affiliation (Current) 2025: 神戸薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help 2017 – 2024: 神戸薬科大学, 薬学部, 准教授
2016: 神戸大学, 医学研究科, 非常勤講師
2012 – 2015: 神戸大学, 医学(系)研究科(研究院), 助教
2014: 神戸大学, 大学院医学研究科, 助教
2012: 神戸大学, 医学研究科, 助教
2011: 神戸大学, 医学部附属病院, 特定助教
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related / Cardiovascular medicine / Circulatory organs internal medicine
Except Principal Investigator
Basic Section 53020:Cardiology-related / Circulatory organs internal medicine
Keywords
Principal Investigator
炎症 / 動脈硬化 / 免疫 / 大動脈瘤 / 免疫細胞 / 動脈硬化症 / 紫外線B波 / 高血圧 / 心不全 / 炎症・免疫反応 / 腹部大動脈瘤 … More
Except Principal Investigator
… More 心房繊維化 / モノサイト / 炎症性単球 / PETMRI / LGEMRI / 心房炎症 / 炎症 / 心房線維化 / LGE-MRI / カテーテルアブレーション / 心房細動 / プロバイオティックス / 腸内細菌細菌叢 / プロバイオティクス / 冠動脈疾患 / 腸内細菌叢 / 免疫寛容性樹状細胞 / 制御性T細胞 / 腸管免疫 / 腸内細菌 / 動脈硬化 Less
  • Research Projects

    (8 results)
  • Research Products

    (128 results)
  • Co-Researchers

    (10 People)
  •  Basic research aimed at developing innovative immunotherapies for atherosclerotic diseasePrincipal Investigator

    • Principal Investigator
      佐々木 直人
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe Pharmaceutical University
  •  Investigation of the mechanisms for the prevention of atherosclerosis by regulatory T cells and development of novel immunotherapiesPrincipal Investigator

    • Principal Investigator
      Sasaki Naoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe Pharmaceutical University
  •  Catheter ablation for atrial fibrosis and inflammation in patients with persistent atrial fibrillation

    • Principal Investigator
      kiuchi kunihiko
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  Investigation of the role of the adaptive immunity in cardiovascular disease and development of therapeutic strategiesPrincipal Investigator

    • Principal Investigator
      Sasaki Naoto
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe Pharmaceutical University
  •  Investigation of the role of immunoinflammatory responses in atherosclerotic disease and development of novel immunotherapiesPrincipal Investigator

    • Principal Investigator
      SASAKI NAOTO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kobe Pharmaceutical University
      Kobe University
  •  Investigation of the role of regulatory T cells in atherosclerotic diseasePrincipal Investigator

    • Principal Investigator
      SASAKI NAOTO
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kobe University
  •  Development of novel therapy for prevention of atherosclerosis via modulating gut bacterial flora and intestinal immunity

    • Principal Investigator
      YAMASHITA Tomoya
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  Investigation of molecular mechanisms of athero-protection by regulatory T cells and development of novel strategies for preventing atherosclerosisPrincipal Investigator

    • Principal Investigator
      SASAKI Naoto
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

  • [Book] 医学のあゆみ2019

    • Author(s)
      佐々木 直人
    • Total Pages
      251
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Book] 医学のあゆみ2013

    • Author(s)
      佐々木直人、平田健一
    • Total Pages
      118
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Journal Article] Novel UV-B Phototherapy With a Light-Emitting Diode Device Prevents Atherosclerosis by Augmenting Regulatory T-Cell Responses in Mice.2024

    • Author(s)
      Tanaka T, Sasaki N, Krisnanda A, Shinohara M, Amin HZ, Horibe S, Ito K, Iwaya M, Fukunaga A, Hirata KI, Rikitake Y.
    • Journal Title

      J Am Heart Assoc

      Volume: 13(2) Issue: 2

    • DOI

      10.1161/jaha.123.031639

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08042, KAKENHI-PROJECT-22H00304
  • [Journal Article] Depletion of Foxp3+ regulatory T cells augments CD4+ T cell immune responses in atherosclerosis-prone hypercholesterolemic mice.2022

    • Author(s)
      Kasahara K, Sasaki N, Amin HZ, Tanaka T, Horibe S, Yamashita T, Hirata KI, Rikitake Y.
    • Journal Title

      Heliyon

      Volume: 8(7) Issue: 7 Pages: e09981-e09981

    • DOI

      10.1016/j.heliyon.2022.e09981

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08042, KAKENHI-PROJECT-20H03676
  • [Journal Article] Cytotoxic T Lymphocyte-Associated Antigen-4 Protects Against Angiotensin II-Induced Kidney Injury in Mice2020

    • Author(s)
      Amin HZ, Sasaki N, Hirata KI, Rikitake Y.
    • Journal Title

      Circulation Reports

      Volume: 2 Issue: 6 Pages: 339-342

    • DOI

      10.1253/circrep.CR-20-0023

    • NAID

      130007853617

    • ISSN
      2434-0790
    • Year and Date
      2020-06-10
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Journal Article] Possible beneficial effects of narrow-band UVB therapy on hypertension and vitamin D levels in patients with cutaneous disease.2019

    • Author(s)
      Emoto T, Sasaki N, Yamashita T, Fukunaga A, Masaki T, Nishigori C, Hirata KI
    • Journal Title

      Photomedicine and Photobiology

      Volume: 40 Pages: 17-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Journal Article] CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice.2019

    • Author(s)
      Amin HZ, Sasaki N, Yamashita T, Mizoguchi T, Hayashi T, Emoto T, Matsumoto T, Yoshida N, Tabata T, Horibe S, Kawauchi S, Rikitake Y, Hirata KI
    • Journal Title

      Scientific Reports

      Volume: 9(1) Issue: 1 Pages: 8065-8065

    • DOI

      10.1038/s41598-019-44523-6

    • NAID

      120006645700

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Journal Article] Ultraviolet B irradiation as a novel strategy to prevent atherosclerotic cardiovascular disease.2018

    • Author(s)
      Sasaki N
    • Journal Title

      Photomedicine and Photobiology

      Volume: 39 Pages: 7-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Journal Article] Regulatory T Cell Immunity in Atherosclerosis.2017

    • Author(s)
      Amin HZ, Sasaki N, Hirata KI.
    • Journal Title

      Acta Med Indones.

      Volume: 49(1) Pages: 63-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Journal Article] UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses.2017

    • Author(s)
      Sasaki, N., T. Yamashita, K. Kasahara, A. Fukunaga, T. Yamaguchi, T. Emoto, K. Yodoi, T. Matsumoto, K. Nakajima, T. Kita, M. Takeda, T. Mizoguchi, T. Hayashi, Y. Sasaki, M. Hatakeyama, K. Taguchi, K. Washio, S. Sakaguchi, B. Malissen, C. Nishigori, and K.I. Hirata
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 37(1) Issue: 1 Pages: 66-74

    • DOI

      10.1161/atvbaha.116.308063

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08530, KAKENHI-PROJECT-15K09156, KAKENHI-PROJECT-16K09516, KAKENHI-PROJECT-16H06295, KAKENHI-PROJECT-15K09742
  • [Journal Article] UVB exposure inhibits angiotensin II-induced abdominal aortic aneurysm formation in mice by expanding CD4+Foxp3+ regulatory T cells.2017

    • Author(s)
      Hayashi T, Sasaki N, Yamashita T, Mizoguchi T, Emoto T, AminHZ, Yodoi K, Matsumoto T, Kasahara K, Yoshida N, Tabata T, Kitano N, Fukunaga A, Nishigori T, Rikitake Y, Hirata K.
    • Journal Title

      J Am Heart Assoc.

      Volume: 6 Issue: 9

    • DOI

      10.1161/jaha.117.007024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09516, KAKENHI-PROJECT-17K09497, KAKENHI-PROJECT-15K09156, KAKENHI-PROJECT-15K09742
  • [Journal Article] Overexpression of Cytotoxic T-Lymphocyte–Associated Antigen-4 Prevents Atherosclerosis in Mice2016

    • Author(s)
      Takuya Matsumoto, Naoto Sasaki, Tomoya Yamashita, Takuo Emoto, Kazuyuki Kasahara, Taiji Mizoguchi, Tomohiro Hayashi, Keiko Yodoi, Naoki kitano, Takashi Saito, Tomoyuki Yamaguchi, and Ken-ichi Hirata
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 36 Issue: 6 Pages: 1141-51

    • DOI

      10.1161/atvbaha.115.306848

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08530, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-15K09156, KAKENHI-PROJECT-16K09516
  • [Journal Article] Anti-inflammatory and immune-modulatory therapies for preventing atherosclerotic cardiovascular disease.2016

    • Author(s)
      Yamashita T, Sasaki N, Kasahara K, Hirata K.
    • Journal Title

      Journal of Cardiology

      Volume: 66(1) Issue: 1 Pages: 1-8

    • DOI

      10.1016/j.jjcc.2015.02.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Journal Article] Foxp3+ regulatory T cells play a protective role in angiotensin II-induced aortic aneurysm formation in mice.2015

    • Author(s)
      Yodoi K, Yamashita T, Sasaki N, Kasahara K, Emoto T, Matsumoto T, Kita T, Sasaki Y, Mizoguchi T, Sparwasser T, Hirata K.
    • Journal Title

      Hypertension

      Volume: 65 Issue: 4 Pages: 889-895

    • DOI

      10.1161/hypertensionaha.114.04934

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591114, KAKENHI-PROJECT-25860601
  • [Journal Article] Intestinal Immunity and Gut Microbiota as Therapeutic Targets for Preventing Atherosclerotic Cardiovascular Diseases2015

    • Author(s)
      Yamashita T, Kasahara K, Emoto T, Matsumoto T, Mizoguchi T, Kitano N, Sasaki N, Hirata K.
    • Journal Title

      Circ J

      Volume: 79 Issue: 9 Pages: 1882-1890

    • DOI

      10.1253/circj.CJ-15-0526

    • NAID

      130005095303

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Journal Article] Regulatory T cells and tolerogenic dendritic cells as critical immune modulators in atherogenesis.2015

    • Author(s)
      Sasaki N, Yamashita T, Kasahara K, Takeda M, Hirata K.
    • Journal Title

      Curr Pharm Des.

      Volume: 21 Pages: 1107-1117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Journal Article] Regulatory T cells and tolerogenic dendritic cells as critical immune modulators in atherogenesis.2015

    • Author(s)
      Sasaki N, Yamashita T, Kasahara K, Takeda M, Hirata K.
    • Journal Title

      Current Pharmaceutical Design

      Volume: 21 Pages: 1107-1117

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Journal Article] 腸から動脈硬化は予防できるのか2014

    • Author(s)
      山下 智也, 笠原 和之, 佐々木 直人, 平田 健一
    • Journal Title

      医学のあゆみ

      Volume: 251 Pages: 100-106

    • Data Source
      KAKENHI-PROJECT-24591114
  • [Journal Article] 腸内細菌と動脈硬化 腸内細菌は新たな心血管病の治療標的となり得るか2014

    • Author(s)
      笠原 和之, 山下 智也, 佐々木 直人, 平田 健一
    • Journal Title

      生物の科学

      Volume: 68 Pages: 358-362

    • Data Source
      KAKENHI-PROJECT-24591114
  • [Journal Article] The regulatory / effector T cell ratio is reduced in coronary artery disease.2014

    • Author(s)
      Emoto T, Sasaki N, Yamashita T, Kasahara K, Yodoi K, Sasaki Y, Matsumoto T, Mizoguchi T, Hirata K.
    • Journal Title

      Circulation Journal

      Volume: 78 Pages: 2935-2941

    • NAID

      130004699205

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Journal Article] Regulatory/effector T-cell ratio is reduced in coronary artery disease.2014

    • Author(s)
      Emoto T, Sasaki N, Yamashita T, Kasahara K, Yodoi K, Sasaki Y, Matsumoto T, Mizoguchi T, Hirata K.
    • Journal Title

      Circulation Journal

      Volume: 78 Pages: 2935-2941

    • NAID

      130004699205

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Journal Article] 腸内フローラへの介入と腸管免疫修飾による動脈硬化予防2014

    • Author(s)
      山下 智也, 笠原 和之, 佐々木 直人, 平田 健一
    • Journal Title

      腸内細菌学雑誌

      Volume: 28 Pages: 1-5

    • NAID

      130003392110

    • Data Source
      KAKENHI-PROJECT-24591114
  • [Journal Article] 腸管は心血管病予防の新たな治療ターゲットになる2013

    • Author(s)
      山下智也、佐々木直人、平田健一
    • Journal Title

      循環器専門医

      Volume: 21 Pages: 291-296

    • Data Source
      KAKENHI-PROJECT-24591114
  • [Journal Article] Regression of atherosclerosis with anti-CD3 antibody via augmenting a regulatory T-cell response in mice.2013

    • Author(s)
      Kita T, Yamashita T, Sasaki N, Kasahara K, Sasaki Y, Yodoi K, Takeda M, Nakajima K, Hirata K.
    • Journal Title

      Cardiovasc Res.

      Volume: 102 Issue: 1 Pages: 107-117

    • DOI

      10.1093/cvr/cvu002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591114, KAKENHI-PROJECT-25860601
  • [Journal Article] CD3 antibody and IL-2 complex combination therapy inhibits atherosclerosis by augmenting a regulatory immune response.2013

    • Author(s)
      Kasahara K, Sasaki N, Yamashita T, Kita T, Yodoi K, Sasaki Y, Takeda M, Hirata K.
    • Journal Title

      J Am Heart Assoc.

      Volume: 3 Issue: 2

    • DOI

      10.1161/jaha.113.000719

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591114, KAKENHI-PROJECT-25860601
  • [Journal Article] Regulatory T cells in atherogenesis.2012

    • Author(s)
      Sasaki N, Yamashita T, Takeda M, Hirata K.
    • Journal Title

      J Atheroscler Thromb.

      Volume: 19 Pages: 503-15

    • NAID

      130004444608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Journal Article] Regulatory T Cells in Atherogenesis.2012

    • Author(s)
      佐々木 直人
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 6 Pages: 503-515

    • NAID

      130004444608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Journal Article] Regulatory T cells in atherogenesis.2012

    • Author(s)
      Sasaki N, Yamashita T, Takeda M, Hirata K
    • Journal Title

      J Atheroscler Thromb

      Volume: 19 Pages: 503-515

    • NAID

      130004444608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Journal Article] Dendritic cells in atherogenesis:Possible novel targets for Prevention of atherosclerosis.2012

    • Author(s)
      Takeda M, Yamashita T,Sasaki N,Hirata K.
    • Journal Title

      J Atheroscler Thromb

      Volume: 19 Pages: 953-961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Journal Article] Dendritic cells in atherogenesis: possible novel targets for prevention of atherosclerosis.2012

    • Author(s)
      Takeda M, Yamashita T, Sasaki N, Hirata K.
    • Journal Title

      J Atheroscler Thromb.

      Volume: 19 Pages: 953-61

    • NAID

      130004444560

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] 特定波長の紫外線B波照射療法は動脈硬化モデルマウスにおいて抗炎症性免疫応答の増強により病変形成を抑制する2024

    • Author(s)
      伊藤謙、佐々木直人、田中亨、Aga Krisnanda、堀部紗世、平田健一、力武良行
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] The specific wavelength of 312 nm UVB irradiation induces a less inflammatory plaque phenotype in atherosclerosis-prone mice.2024

    • Author(s)
      Aga Krisnanda, Naoto Sasaki, Toru Tanaka, Ken Ito, Sayo Horibe, Yoshiyuki Rikitake
    • Organizer
      第88回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 動脈硬化性疾患とがんにおけるT細胞免疫応答の役割の違い2023

    • Author(s)
      佐々木直人、田中亨、力武良行
    • Organizer
      第55回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] Effects of specific wavelengths of ultraviolet B irradiation on immunoinflammatory responses and atherosclerosis progression.2023

    • Author(s)
      Aga Krisnanda, Naoto Sasaki, Toru Tanaka, Sayo Horibe, Yoshiyuki Rikitake
    • Organizer
      第87回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 特定波長の紫外線B波照射による動脈硬化抑制機序の解明2023

    • Author(s)
      佐々木直人、田中亨、Aga Krisnanda、篠原正和、福永淳、力武良行
    • Organizer
      第45回日本光医学・光生物学会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 特定波長の紫外線B波による抗動脈硬化作用 ―アポリポ蛋白E遺伝子欠損マウスを用いた解析―2023

    • Author(s)
      伊藤謙、佐々木直人、田中亨、Aga Krisnanda、堀部紗世、平田健一、力武良行
    • Organizer
      第73回日本薬学会関西支部総会・大会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 特定波長の紫外線B波が免疫反応および動脈硬化に与える影響2022

    • Author(s)
      Aga Krisnanda、佐々木直人、田中亨、Hilman Zulkifli Amin、赤井瑞希、池内一真、石坂麻衣、伊藤謙、岡本拓朗、倉敷治央、田原由貴、野尻真那、堀部紗世、平田健一、力武良行
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] Modulation of T cell immune balance as an attractive strategy to treat atherosclerosis.2022

    • Author(s)
      Naoto Sasaki, Yoshiyuki Rikitake
    • Organizer
      第86回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 獲得免疫系による動脈硬化制御機構の解明と治療応用2022

    • Author(s)
      佐々木直人、力武良行
    • Organizer
      第54回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 動脈硬化抑制に有効な紫外線B波の波長の探索2022

    • Author(s)
      佐々木直人、田中亨、福永淳、力武良行
    • Organizer
      第44回日本光医学・光生物学会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 特定の紫外線B波照射による動脈硬化抑制効果の検討2021

    • Author(s)
      佐々木直人、福永淳、錦織千佳子、力武良行
    • Organizer
      第42回日本光医学・光生物学会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Identification of specific wavelengths of ultraviolet B for preventing atherosclerosis and their mechanisms of action.2021

    • Author(s)
      Toru Tanaka, Naoto Sasaki, Hilman Zulkifli Amin, Ken-ichi Hirata, Yoshiyuki Rikitake
    • Organizer
      第5回日本循環器学会基礎研究フォーラム
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 動脈硬化抑制に有効な紫外線B波の波長の特定とその機序の解明2021

    • Author(s)
      田中亨、佐々木直人、Hilman Zulkifli Amin、力武良行
    • Organizer
      第53回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] Development of a novel anti-inflammatory phototherapy against atherosclerosis.2021

    • Author(s)
      Toru Tanaka, Naoto Sasaki, Hilman Zulkifli Amin, Yoshiyuki Rikitake
    • Organizer
      第19回国際動脈硬化学会議
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08042
  • [Presentation] 特定波長の紫外線B波による動脈硬化抑制効果とその機序の解明2021

    • Author(s)
      田中亨、佐々木直人、西村紗良、井戸花乃、山口悠馬、武岡侑希、中村百花、浜田悠花、Amin Hilman Zulkifli、堀部紗世、平田健一、力武良行
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Development of novel LED phototherapy to limit atherosclerosis.2021

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Yoshiyuki Rikitake
    • Organizer
      第85回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Pharmacological inhibition of C-C chemokine receptor 4 aggravates atherosclerosis through prevention of regulatory T cell recruitment to the lesions.2020

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Sayo Horibe, Shoji Kawauchi, Ken-ichi Hirata, Yoshiyuki Rikitake
    • Organizer
      European Society of Cardiology Congress, 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Protective T-cell Immunity as an Attractive Therapeutic Target for Atherosclerotic Disease.2020

    • Author(s)
      Naoto Sasaki, Hilman Zulkifli Amin, Yoshiyuki Rikitake
    • Organizer
      第52回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Selective C-C chemokine receptor 4 inhibition aggravates atherosclerosis in apolipoprotein E-deficient mice.2020

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Ken-ichi Hirata, Yoshiyuki Rikitake
    • Organizer
      第84回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] 動脈硬化モデルマウスにおける病変形成抑制に有効な紫外線B波の波長の特定2020

    • Author(s)
      大内友梨香、佐々木直人、有地珠里、嶋本美咲、野口恵美、Hilman Zulkifli Amin、堀部紗世、河内正二、平田健一、力武良行
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Overexpression of cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) protects against abdominal aortic aneurysm formation in mice.2019

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Tomoya Yamashita, Taiji Mizoguchi, Tomohiro Hayashi, Takuo Emoto, Takuya Matsumoto, Naofumi Yoshida, Tokiko Tabata, Sayo Horibe, Shoji Kawauchi, Yoshiyuki Rikitake, Ken-ichi Hirata
    • Organizer
      第83回日本循環器学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Overexpression of cytotoxic T-lymphocyte-associated antigen-4 suppresses aortic immunoinflammatory responses and prevents angiotensin II-induced abdominal aortic aneurysm formation in mice.2019

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Tomoya Yamashita, Taiji Mizoguchi, Tomohiro Hayashi, Takuo Emoto, Takuya Matsumoto, Naofumi Yoshida, Tokiko Tabata, Sayo Horibe, Shoji Kawauchi, Yoshiyuki Rikitake, Ken-ichi, Hirata
    • Organizer
      European Society of Cardiology Congress, 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Immune Checkpoint Proteins and Regulatory T Cells as Critical Immune Modulators in Atherosclerotic Disease and Cancer.2019

    • Author(s)
      Naoto Sasaki, Hilman Zulkifli Amin, Yoshiyuki Rikitake
    • Organizer
      第83回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] 共抑制分子CTLA-4はアンジオテンシンⅡ誘導性マウス腹部大動脈瘤の形成を抑制する2019

    • Author(s)
      佐々木直人、Hilman Zulkifli Amin、堀部紗世、河内正二、平田健一、力武良行
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Overexpression of cytotoxic T-lymphocyte-associated antigen-4 suppresses aortic immunoinflammatory responses and prevents angiotensin II-induced abdominal aortic aneurysm formation in mice.2019

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Tomoya Yamashita, Taiji Mizoguchi, Tomohiro Hayashi, Takuo Emoto, Takuya Matsumoto, Naofumi Yoshida, Tokiko Tabata, Sayo Horibe, Shoji Kawauchi, Yoshiyuki Rikitake, Ken-ichi, Hirata
    • Organizer
      European Society of Cardiology Asia Congress 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] 紫外線を用いた新規心血管疾患治療法の開発2019

    • Author(s)
      佐々木直人、福永淳、錦織千佳子、力武 良行
    • Organizer
      第39回日本光医学・光生物学会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] 動脈硬化性疾患に対する新規免疫療法の開発2019

    • Author(s)
      佐々木直人、力武良行
    • Organizer
      第51回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Treating atherosclerotic disease by modulating T cell immune responses.2018

    • Author(s)
      Naoto Sasaki
    • Organizer
      XVIIIth International Symposium on Atherosclerosis
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] CTLA-4 protects against experimental abdominal aortic aneurysm formation.2018

    • Author(s)
      Naoto Sasaki
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] Overexpression of cytotoxic T-lymphocyte-associated antigen-4 protects against abdominal aortic aneurysm formation in mice.2018

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Tomoya Yamashita, Taiji Mizoguchi, Yoshiyuki Rikitake, Ken-ichi, Hirata
    • Organizer
      The 90th AHA Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] 紫外線照射による心血管疾患発症・進展の抑制機序の検討と臨床応用2018

    • Author(s)
      佐々木直人、福永淳、錦織千佳子、山下智也、平田健一、力武良行
    • Organizer
      第40回日本光医学・光生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] 紫外線照射による動脈硬化性疾患に対する抑制効果の検討2018

    • Author(s)
      佐々木直人、溝口泰司、Hilman Zulkifli Amin、堀部紗世、河内正二、山下智也、平田健一、力武良行
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 動脈硬化性疾患とがんにおける免疫チェックポイントタンパク質と制御性T細胞の役割2018

    • Author(s)
      佐々木直人、山下智也、平田健一、力武良行
    • Organizer
      第50回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-18K08088
  • [Presentation] 紫外線照射は制御性T細胞の誘導を介して心筋梗塞の予後を改善させる2017

    • Author(s)
      佐々木直人、溝口泰司、福永淳、錦織千佳子、山下智也、平田健一、力武良行
    • Organizer
      第39回日本光医学・光生物学会
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Ultraviolet B Irradiation Inhibits the Development of Angiotensin II-Induced Abdominal Aortic Aneurysm Formation by Regulating Immuno-Inflammatory Responses2017

    • Author(s)
      Tomohiro Hayashi, Naoto Sasaki, Tomoya Yamashita, Takuo Emoto, Taiji Mizoguchi, Naofumi Yoshida, Tokiko Tabata, Hilman Zulkifli Amin, Ken-ichi Hirata
    • Organizer
      第81回日本循環器学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Foxp3+ regulatory T cells inhibit the development of atherosclerosis by regulating immunoinflammatory responses2017

    • Author(s)
      Hilman Zulkifli Amin, Naoto Sasaki, Kazuyuki Kasahara, Takuo Emoto, Tomohiro Hayashi, Taiji Mizoguchi, Yoshiyuki Rikitake, Tomoya Yamashita, Ken-ichi Hirata
    • Organizer
      第49回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Ultraviolet B exposure prevents atherosclerotic cardiovascular disease by regulating immunoinflammatory responses2017

    • Author(s)
      Naoto Sasaki
    • Organizer
      第46回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 紫外線照射による動脈硬化抑制効果の検討2017

    • Author(s)
      佐々木直人、林友鴻、福永淳、錦織千佳子、山下智也、平田健一、力武良行
    • Organizer
      第39回日本光医学・光生物学会
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] アンギオテンシンII誘導性マウス大動脈瘤モデルを用いた、紫外線照射による大動脈瘤抑制効果の検討2017

    • Author(s)
      林友鴻、佐々木直人、江本拓央、溝口泰司、吉田尚史、田畑論子、Hilman Zulkifli Amin、山下智也、平田健一
    • Organizer
      第49回日本動脈硬化学会総会
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 紫外線照射による心筋梗塞後の心不全抑制効果の検討2017

    • Author(s)
      佐々木直人、溝口泰司、Hilman Zulkifli Amin、力武良行、山下智也、平田健一
    • Organizer
      第45回日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Oral administration of the Lactic Acid Bacterium Pediococcus acidilactici attenuates atherosclerosis via inducing tolerogenic dendritic cells in mice2016

    • Author(s)
      Taiji Mizoguchi, Kazuyuki Kasahara, Tomoya Yamashita, Naoto Sasaki, Takuya Matsumoto, Takuo Emoto, Tomohiro Hayashi, Keiko Yodoi, Naoki Kitano, Ken-ichi Hirata
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Ultraviolet B exposure prevents atherosclerosis2016

    • Author(s)
      Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Takuo Emoto, Takuya Matsumoto, Taiji Mizoguchi, Tomohiro Hayashi, Ken-ichi Hirata
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Gut microbiota could be a predictor of the risk of coronary atherosclerosis.2016

    • Author(s)
      Takuo Emoto, Tomoya Yamashita, Toshio Kobayashi, Naoto Sasaki, Kazuyuki Kasahara, Keiko Yodoi, Takuya Matsumoto, Taiji Mizoguchi, Tomohiro Hayashi, Ken-ichi Hirata
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Co-inhibitory molecule CTLA-4 regulates atherosclerosis by suppressing T cell and dendritic cell activation in mice2016

    • Author(s)
      Naoto Sasaki, Takuya Matsumoto, Takuo Emoto, Taiji Mizoguchi, Tomohiro Hayashi, Tomoya Yamashita, Ken-ichi Hirata
    • Organizer
      第48回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] アンギオテンシンⅡ誘導性マウス大動脈瘤モデルを用いた、UVB照射による大動脈瘤抑制効果の検討2016

    • Author(s)
      林友鴻、 佐々木直人、 江本拓央、 溝口泰司、 吉田尚史、 Hilman Zulkifli Amin、 松本卓也、山下智也、平田 健一
    • Organizer
      第48回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 動脈硬化における制御性T細胞の役割2016

    • Author(s)
      佐々木直人、山下智也、平田健一
    • Organizer
      第48回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Overexpression of CTLA-4 prevents atherosclerosis by suppressing T cell activation in mice2016

    • Author(s)
      Takuya Matsumoto, Naoto Sasaki, Takuo Emoto, Taiji Mizoguchi, Tomohiro Hayashi, Tomoya Yamashita, Ken-ici Hirata
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Ultraviolet B Exposure Limits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice2016

    • Author(s)
      Tomohiro Hayashi, Naoto Sasaki, Tomoya Yamashita, Takuo Emoto, Taiji Mizoguchi, Naofumi Yoshida, Tokiko Tabata, Hilman Zulkifli Amin, Ken-ichi Hirata
    • Organizer
      第24回日本血管生物医学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Foxp3+ Regulatory T Cells and T Regulatory Type 1 Cells Cooperatively Inhibit the Development of Atherosclerosis in Mice2015

    • Author(s)
      Kazuyuki Kasahara, Naoto Sasaki, Tomoya Yamashita, Keiko Yodoi, Takuya Matsumoto, Takuo Emoto, Taiji Mizoguchi, Ken-ichi Hirata
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Foxp3+ Regulatory T Cells Play a Protective Role in Angiotensin II-induced Aortic Aneurysm Formation in Mice2015

    • Author(s)
      Keiko Yodoi, Tomoya Yamashita, Naoto Sasaki, Kazuyuki Kasahara, Yoshihiro Sasaki, Takuo Emoto, Takuya Matsumoto, Taiji Mizoguchi, Tomoyuki Kita, Ken-ichi Hirata
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 冠動脈疾患患者における腸内細菌叢の特徴2015

    • Author(s)
      江本 拓央、山下 智也、佐々木 直人、笠原 和之、淀井 景子、松本 卓也、溝口 泰司、林 友鴻、平田 健一
    • Organizer
      第23回日本血管生物医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-10
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Regulatory T Cells and Tolerogenic Dendritic Cells are Critical Immunomodulators Linking the Skin and Intestinal Immune System to Atherosclerosis2015

    • Author(s)
      Naoto Sasaki, Tomoya Yamashita, Ken-ichi Hirata
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 紫外線(UVB)照射による動脈硬化抑制効果の検討2015

    • Author(s)
      佐々木直人、山下智也、福永淳、山口智之、坂口志文、錦織千佳子、平田健一
    • Organizer
      第43回日本臨床免疫学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 共免疫抑制分子CTLA-4による動脈硬化抑制機構の解明2015

    • Author(s)
      松本 卓也、佐々木 直人、江本 拓央、溝口 泰司、林 友鴻、吉田 尚史、山下 智也、平田 健一
    • Organizer
      第23回日本血管生物医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-10
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Intestinal Immunity and Gut Microbiota as Therapeutic Targets for Preventing Atherosclerotic Cardiovascular Diseases2015

    • Author(s)
      Tomoya Yamashita, Naoto Sasaki, Ken-ichi Hirata
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] A Characteristic Change of Gut Microbiota in Coronary Artery Disease2015

    • Author(s)
      Takuo Emoto, Tomoya Yamashita, Naoto Sasaki, Kazuyuki Kasahara, Keiko Yodoi, Takuya Matsumoto, Taiji Mizoguchi, Tomohiro Hayashi, Ken-ichi Hirata
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] 紫外線(UVB)照射を用いた新規動脈硬化治療法の開発2015

    • Author(s)
      佐々木直人、山下智也、笠原 和之、福永淳、山口智之、江本 拓央、淀井 景子、松本 卓也、中島 健爾、北 智之、武田 匡史、溝口 泰司、林 友鴻、佐々木 義浩、畠山 真弓、田口 久美子、鷲尾 健、坂口志文、錦織千佳子、平田健一
    • Organizer
      第23回日本血管生物医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-10
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] Proatherogenic Immune Responses are Regulated by Overexpression of a Coinhibitory Molecule CTLA-4 in Apolipoprotein E-deficient Mice2015

    • Author(s)
      Takuya Matsumoto, Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Keiko Yodoi, Takuo Emoto, Taiji Mizoguchi, Ken-ichi Hirata
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-15K09156
  • [Presentation] アンジオテンシンII負荷腹部大動脈瘤マウスモデルにおける制御性T細胞の役割の検討2014

    • Author(s)
      Keiko Yodoi, Tomoya Yamashita, Naoto Sasaki, Tomoyuki Kita, Kazuyuki Kasahara, Yoshihiro Sasaki, Takuo Emoto, Takuya Matsumoto, Taiji Mizoguchi, Ken-ichi Hirata
    • Organizer
      第43回日本心血管作動物質学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] 抗CD3抗体とIL-2複合体の併用療法は、アポE欠損マウスにおけるエフェクターT細胞と制御性T細胞のバランスを変化させ、動脈硬化を抑制する2014

    • Author(s)
      Kazuyuki Kasahara, Naoto Sasaki, Tomoya Yamashita, Yoshihiro Sasaki, Keiko Yodoi, Takuo Emoto, Takuya Matsumoto, Ken-ichi Hirata
    • Organizer
      第43回日本心血管作動物質学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Novel therapeutic strategies for preventing atherosclerosis via modulating intestinal immunity and intervention to gut microflora.2013

    • Author(s)
      Tomoya Yamashita, Naoto Sasaki, Ken-ichi Hirata
    • Organizer
      第17回腸内細菌学会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] A novel mouse model to deplete regulatory T cells uncovers their role in atherogenesis under hypercholesterolemia.2013

    • Author(s)
      笠原 和之、佐々木 直人
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      神奈川県横浜市
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] Intestine and skin could be novel therapeutic targets for preventing cardiovascular diseases.2013

    • Author(s)
      山下智也、佐々木直人、平田健一
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] A novel mouse model to deplete regulatory T cells uncovers their role in atherogenesis under hypercholesterolemia2013

    • Author(s)
      Kazuyuki Kasahara, Tomoya Yamashita, Naoto Sasaki, Tomoyuki Kita, Yoshihiro Sasaki, Keiko Yodoi, Takuo Emoto, Takuya Matsumoto, Ken-ichi Hirata
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] A novel combination therapy with anti-CD3 antibody and IL-2 complexes against atherosclerosis targeting effector T cells and regulatory T cells2013

    • Author(s)
      Kazuyuki Kasahara, Naoto Sasaki, Tomoya Yamashita, Yoshihiro Sasaki, Keiko Yodoi, Takuya Matsumoto, Takuo Emoto, Ken-ichi Hirata
    • Organizer
      Scientific Session of American Heart Association
    • Place of Presentation
      Dallas, Texas, USA
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] Activation of skin dendritic cells controls atherogensis in mice.2013

    • Author(s)
      Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Tomoyuki Kita, Yoshihiro Sasaki, Keiko Yodoi, Ken-ichi Hirata.
    • Organizer
      Scientific Session of American Heart Association
    • Place of Presentation
      Dallas, Texas, USA
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] A novel combination therapy with anti-CD3 antibody and IL-2 complexes against atherosclerosis targeting effector T cells and regulatory T cells2013

    • Author(s)
      Kazuyuki Kasahara, Tomoya Yamashita, Naoto Sasaki, Tomoyuki Kita, Yoshihiro Sasaki, Keiko Yodoi, Takuo Emoto, Takuya Matsumoto, Ken-ichi Hirata
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] In vivo Expansion of Regulatory T Cells Attenuates Aortic Aneurysm Formation in Angiotensin II- Infused Apolipoprotein E-deficient Mice.2013

    • Author(s)
      Keiko Yodoi, Naoto Sasaki, Taiji Mizoguchi, Takuya Matsumoto, Takuo Emoto, Yoshihiro Sasaki, Kazuyuki Kasahara, Tomoyuki Kita, Tomoya Yamashita, Ken-ichi
    • Organizer
      Scientific Session of American Heart Association
    • Place of Presentation
      Dallas, Texas, USA
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] A novel mouse model to deplete regulatory T cells uncovers their role in atherogenesis under hypercholesterolemia2013

    • Author(s)
      Kasahara K, Sasaki N
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-15
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] In vivo expansion of regulatory T cells attenuates aortic aneurysm formation in angiotensin II- infused apolipoprotein E-deficient mice2013

    • Author(s)
      Keiko Yodoi, Tomoya Yamashita, Naoto Sasaki, Tomoyuki Kita, Kazuyuki Kasahara, Yoshihiro Sasaki, Takuo Emoto, Takuya Matsumoto, Ken-ichi Hirata
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] Activation of regulatory T cells by ultraviolet irradiation controls atherogenesis in mice2012

    • Author(s)
      Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Kenji Nakajima, Tomoyuki Kita, Yoshihiro Sasaki, Keiko Yodoi, Masafumi Takeda, Ken-ichi Hirata
    • Organizer
      第85回米国心臓学会議
    • Place of Presentation
      ロスアンゼルスコンベンションセンター(ロスアンゼルス、米国)
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] Activation of regulatory T cells by ultraviolet irradiation controls atherogenesis in mice2012

    • Author(s)
      Sasaki N
    • Organizer
      第85回米国心臓学会議
    • Place of Presentation
      米国 ロサンゼルス
    • Year and Date
      2012-11-06
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] 動脈硬化性疾患予防・治療のための抗炎症戦略 -制御性T細胞誘導を介する抗動脈硬化免疫療法の試み-2012

    • Author(s)
      佐々木 直人
    • Organizer
      第34回心筋生検研究会
    • Place of Presentation
      長野県松本市 信州大学医学部附属病院
    • Invited
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] A novel ultraviolet-based phototherapy against atherosclerosis targeting regulatory T cells and skin dendritic cells2012

    • Author(s)
      佐々木 直人
    • Organizer
      XVI International Symposium on Atherosclerosis (ISA2012)
    • Place of Presentation
      オーストラリア シドニー Sydney Convention and Exhibition Centre
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] A novel ultraviolet-based phototherapy against atherosclerosis targeting regulatory T cells and skin dendritic cells2012

    • Author(s)
      Sasaki N
    • Organizer
      第76回日本循環器学会総会・学術集会 Young Investigator's Award優秀賞受賞講演
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] Anti-atherogenic role of ultraviolet radiation -induced regulatory T cells in a mouse model of atherosclerosis2012

    • Author(s)
      Sasaki N
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2012-12-06
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] 動脈硬化性疾患予防・治療のための抗炎症戦略 -制御性T細胞誘導を介する抗動脈硬化免疫療法の試み-2012

    • Author(s)
      佐々木 直人
    • Organizer
      第34回心筋生検研究会・招待講演
    • Place of Presentation
      松本
    • Year and Date
      2012-11-24
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] 腸管免疫修飾による新規動脈硬化予防法の開発2012

    • Author(s)
      山下智也、佐々木直人、平田健一
    • Organizer
      第44回日本動脈硬化学会総会
    • Place of Presentation
      シーホークホテル(福岡)
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] Anti-atherogenic role of ultraviolet radiation-induced regulatory T cells in a mouse model of atherosclerosis2012

    • Author(s)
      佐々木 直人
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      兵庫県神戸市 神戸国際会議場・神戸国際展示場・神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] Activation of regulatory T cells by ultraviolet irradiation controls atherogenesis in mice2012

    • Author(s)
      佐々木 直人
    • Organizer
      第85回米国心臓学会議
    • Place of Presentation
      アメリカ合衆国 ロサンゼルス コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] A novel ultraviolet-based phototherapy against atherosclerosis targeting regulatory T cells and skin dendritic cells2012

    • Author(s)
      佐々木 直人
    • Organizer
      第76回日本循環器学会総会・学術集会
    • Place of Presentation
      福岡県福岡市 福岡サンパレス
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] A novel ultraviolet-based phototherapy against atherosclerosis targeting regulatory T cells and skin dendritic cells2012

    • Author(s)
      Sasaki N
    • Organizer
      XVI International Symposium on Atherosclerosis (ISA2012)
    • Place of Presentation
      オーストラリア シドニー
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-23790849
  • [Presentation] In vivo expansion of regulatory T cells attenuates aortic aneurysm formation in angiotensin II- infused apolipoprotein E-deficient mice

    • Author(s)
      Keiko Yodoi, Naoto Sasaki,Taiji Mizoguchi, Takuya Matsumoto, Takuo Emoto, Yoshihiro Sasaki, Kazuyuki Kasahara, Tomoyuki Kita, Tomoya Yamashita, Ken-ichi Hirata
    • Organizer
      第86回米国心臓学会議
    • Place of Presentation
      ダラス(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Anti-CD3 antibody and interleukin-2 complex combination therapy inhibits atherosclerosis development by dramatically augmenting a regulatory immune response

    • Author(s)
      Kazuyuki Kasahara, Naoto Sasaki, Tomoya Yamashita, Yoshihiro Sasaki, Keiko Yodoi, Ken-ichi Hirata
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] A novel combination therapy with anti-CD3 antibody and IL-2 complexes against atherosclerosis targeting effector T cells and regulatory T cells

    • Author(s)
      Kazuyuki Kasahara, Tomoya Yamashita, Naoto Sasaki, Yoshihiro Sasaki, Keiko Yodoi, Ken-ichi Hirata
    • Organizer
      第86回米国心臓学会議
    • Place of Presentation
      ダラス(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Regulatory T Cells Play a Protective Role in Angiotensin II-Induced Aortic Aneurysm Formation

    • Author(s)
      Keiko Yodoi, Tomoya Yamashita, Naoto Sasaki, Kazuyuki Kasahara, Yoshihiro Sasaki, Takuo Emoto, Takuya Matsumoto,Taiji Mizoguchi, Ken-ichi Hirata
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] 腸内細菌と動脈硬化

    • Author(s)
      山下智也、佐々木直人、平田健一
    • Organizer
      第46回日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] The effector/ regulatory T cell ratio is reduced in coronary artery disease

    • Author(s)
      Takuo Emoto, Naoto Sasaki, Taiji Mizoguchi, Takuya Matsumoto, Keiko Yodoi, Yoshihiro Sasaki, Kazuyuki Kasahara, Tomoya Yamashita, Ken-ichi Hirata
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Regulatory T cells and CD4+CD28null T cells in coronary artery disease

    • Author(s)
      Takuo Emoto, Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Keiko Yodoi, Yoshihiro Sasaki, Takuya Matsumoto, Taiji Mizoguchi, Ken-ichi Hirata
    • Organizer
      第46回日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-24591114
  • [Presentation] Activation of skin dendritic cells controls atherogensis in mice

    • Author(s)
      Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Tomoyuki Kita, Yoshihiro Sasaki, Keiko Yodoi, Ken-ichi Hirata
    • Organizer
      第86回米国心臓学会議
    • Place of Presentation
      ダラス(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Regression of atherosclerosis with anti-CD3 antibody via modulating the ratio of effector and regulatory T cells in mice

    • Author(s)
      Yoshihiro Sasaki, Naoto Sasaki, Tomoya Yamashita, Tomoyuki Kita, Kazuyuki Kasahara, Keiko Yodoi, Ken-ichi Hirata
    • Organizer
      第45回日本動脈硬化学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] The effects in vivo expansion of regulatory T cells on abdominal aortic aneurysm in the angiotensin II-induced murine model

    • Author(s)
      Keiko Yodoi, Tomoya Yamashita, Naoto Sasaki, Tomoyuki Kita, Kazuyuki Kasahara, Yoshihiro Sasaki, Takuo Emoto, Takuya Matsumoto, Ken-ichi Hirata
    • Organizer
      第45回日本動脈硬化学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Gut microbiota modulates coronary atherogenesis

    • Author(s)
      Takuo Emoto, Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Keiko Yodoi, Yoshihiro Sasaki, Takuya Matsumoto, Taiji Mizoguchi, Ken-ichi Hirata
    • Organizer
      第46回日本動脈硬化学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-10 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] The balance between regulatory T cells and effector T cells is important for the control of atherosclerosis

    • Author(s)
      Kazuyuki Kasahara, Tomoya Yamashita, Naoto Sasaki, Yoshihiro Sasaki, Keiko Yodoi, Ken-ichi Hirata
    • Organizer
      第45回日本動脈硬化学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Activation of skin dendritic cells controls atherogensis in mice

    • Author(s)
      Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Tomoyuki Kita, Yoshihiro Sasaki, Keiko Yodoi, Takuo Emoto, Takuya Matsumoto, Ken-ichi Hirata
    • Organizer
      第45回日本動脈硬化学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Regulation of Pathogenic Inflammatory Responses via Modulating Skin Immune System for Prevention of Atherosclerosis

    • Author(s)
      Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Yoshihiro Sasaki, Keiko Yodoi, Ken-ichi Hirata
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] 免疫制御による動脈硬化性疾患予防・治療戦略

    • Author(s)
      佐々木直人、山下智也、平田健一
    • Organizer
      第43回日本心血管作動物質学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25860601
  • [Presentation] Regulatory T cells and CD4+CD28null T cells in coronary artery disease

    • Author(s)
      Takuo Emoto, Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Keiko Yodoi, Yoshihiro Sasaki, Takuya Matsumoto, Taiji Mizoguchi, Ken-ichi Hirata
    • Organizer
      第46回日本動脈硬化学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-10 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-25860601
  • 1.  YAMASHITA Tomoya (90437468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 24 results
  • 2.  MIZOGUCHI TAIJI (40806882)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 20 results
  • 3.  kiuchi kunihiko (50777612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  福沢 公二 (70535856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  大竹 寛雅 (60593803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KASAHARA KAZUYUKI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 7.  EMOTO TAKUO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 8.  HAYASHI TOMOHIRO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 9.  MATSUMOTO TAKUYA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 10.  YAMAGUCHI Tomoyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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