Goto Toshiyasu 後藤利保

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GOTO Toshiyasu 後藤利保

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Researcher Number	00517518
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 准教授
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 難治疾患研究所, 准教授 2012 – 2017: 東京医科歯科大学, 難治疾患研究所, 准教授
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 44020:Developmental biology-related Except Principal Investigator General medical chemistry
Keywords	Principal Investigator アフリカツメガエル / β-catenin / シグナル伝達 / Wnt / アフリカ爪ガエル / ユビキチン化 / beta-catenin / WDR26 / 核内移行 / IQGAP1 … More Except Principal Investigator … More OSR1 / シグナル伝達 / Arroehead / Fray / 高血圧症 / WNK4 / WNK1 / Lhx8 / 標的遺伝子 / 神経分化 / 細胞内シグナル / Lhx8/Awh / ショウジョウバエ / PHAII / WNK Less

収斂伸長運動におけるCell Intercalationの分子機構の解析Principal Investigator
- Principal Investigator
  
  後藤利保
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Institute of Science Tokyo
Analysis of degradation mechanisms through WDR26 in Wnt signalingPrincipal Investigator
- Principal Investigator
  
  GOTO Toshiyasu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Analysis of beta-catenin nuclear translocation mechanism through IQGAP1 in Wnt signaling.Principal Investigator
- Principal Investigator
  
  GOTO Toshiyasu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Characterization of WNK signaling in development
- Principal Investigator
  
  HIROSHI Shibuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University

All 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis.2018
- Author(s)
  Goto T., Ito Y., Michiue T.
- Journal Title
  
  Dev Growth Differ.
  
  Volume: 印刷中 Issue: 4 Pages: 226-238
- DOI
  10.1111/dgd.12432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08262, KAKENHI-PROJECT-18K11544
[Journal Article] High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis.2017
- Author(s)
  Michiue T, Yamamoto T, Yasuoka Y, Goto T, Nakayama T, Nagura K, Ikeda T, Taira M, Kinoshita T
- Journal Title
  
  Dev. Biol.
  
  Volume: 印刷中 Issue: 2 Pages: 270-290
- DOI
  10.1016/j.ydbio.2016.12.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440115, KAKENHI-PROJECT-15K08262, KAKENHI-PROJECT-17KT0114, KAKENHI-PROJECT-16K21559
[Journal Article] WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway2016
- Author(s)
  Goto T., Matsuzawa J., Iemura S., Natsume T., Shibuya H.
- Journal Title
  
  FEBS Letters
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08262
[Journal Article] Selective inhibition of the kinase DYRK1A by targeting its folding process2016
- Author(s)
  Kii I., Sumida Y., Goto T., Sonamoto R., Okuno Y., Yoshida S., Kato-Sumida T., Koike Y., Abe M., Nonaka Y., Ikura T., Ito N., Shibuya H., Hosoya T., Hagiwara M.
- Journal Title
  
  Nat. Commun.
  
  Volume: 該当なし Issue: 1 Pages: 11391-11391
- DOI
  10.1038/ncomms11391
- NAID
  120005770755
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08262, KAKENHI-PROJECT-16H05926, KAKENHI-PROJECT-15H05721, KAKENHI-PROJECT-21249013
[Journal Article] IQGAP1 functions as a modulator of Dishevelled nuclear localization in Wnt signaling.2013
- Author(s)
  Goto, T.
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390064
[Journal Article] Characterization of CXC-type chemokine molecules in early Xenopus laevis development.2013
- Author(s)
  Goto T, et al.
- Journal Title
  
  Int J Dev Biol.
  
  Volume: 57 Issue: 1 Pages: 41-47
- DOI
  10.1387/ijdb.120223ma
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570200, KAKENHI-PROJECT-24590344
[Journal Article] IQGAP1 regulates nuclear localization of β-Catenin via importin-β5 in Wnt signaling.2013
- Author(s)
  Goto. T, Sato, A., Adachi, S., Iemura, S., Natsume, T. and Shibuya, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 51 Pages: 36351-36360
- DOI
  10.1074/jbc.m113.520528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390064, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-24590344
[Journal Article] IQGAP1 functions as a modulator of Dishevelled nuclear localization in Wnt signaling2013
- Author(s)
  Goto, T., Sato, A., Shimizu, M., Adachi, S., Satoh, K., Iemura, S., Natsume, T. and Shibuya, H
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e60865-e60865
- DOI
  10.1371/journal.pone.0060865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390064, KAKENHI-PROJECT-23790358, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-24590344
[Journal Article] WNK4 is an essential effector of anterior formation in FGF signaling2013
- Author(s)
  Shimizu, M., Goto, T., Sato, A. and Shibuya, H
- Journal Title
  
  Genes Cells
  
  Volume: 18 Issue: 6 Pages: 442-449
- DOI
  10.1111/gtc.12048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390064, KAKENHI-PROJECT-23790358, KAKENHI-PROJECT-24590344
[Journal Article] IQGAP1 protein regulates nuclear localization of ・ -catenin via importin- ・ 5 in Wnt signaling2013
- Author(s)
  Goto, T., Sato, A., Shimizu, M., Adachi, S., Satoh, K., Iemura, S., Natsume, T. and Shibuya, H
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 36351-36360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390064
[Presentation] beta-catenin の分解におけるWDR26 の機能解析2017
- Author(s)
  後藤利保
- Organizer
  第１１回ツメガエル研究集会
- Data Source
  KAKENHI-PROJECT-15K08262
[Presentation] WDR26 shows novel ubiquitination sites in beta-catenin degradation.2016
- Author(s)
  後藤利保、松澤純平、家村俊一郎、夏目徹、澁谷浩司
- Organizer
  第３９回日本分子生物学会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-15K08262
[Presentation] WDR26 is a new patner of Axin1 in canonical Wnt signaling Pathway.2015
- Author(s)
  後藤利保、松澤純平、家村俊一郎、夏目徹、澁谷浩司
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（兵庫県　神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08262
[Presentation] IQGAP1によるβ-cateninの核内移行の調節機構の解析2013
- Author(s)
  後藤利保、佐藤淳、足立俊吾、家村俊一郎、夏目徹、澁谷浩司
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390064
[Presentation] IQGAP1によるß-cateninの核内移行の調節機構の解析2013
- Author(s)
  ○後藤利保、佐藤淳、足立俊吾、家村俊一郎、夏目徹、澁谷浩司
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590344
[Presentation] IQGAP1 によるβ-catenin の核内移行の調節機構の解析2013
- Author(s)
  後藤利保,佐藤淳,足立俊吾,家村俊一郎,夏目徹, 澁谷浩司
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸,ポスター発表
- Data Source
  KAKENHI-PROJECT-23390064

1. HIROSHI Shibuya (30261324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. SATO Atsushi (30451925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 道上達男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Goto Toshiyasu 後藤 利保

GOTO Toshiyasu 後藤 利保

Research Projects

Research Products

Co-Researchers

収斂伸長運動におけるCell Intercalationの分子機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of degradation mechanisms through WDR26 in Wnt signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of beta-catenin nuclear translocation mechanism through IQGAP1 in Wnt signaling.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of WNK signaling in development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway2016

Author(s)

Journal Title

Data Source

[Journal Article] Selective inhibition of the kinase DYRK1A by targeting its folding process2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] IQGAP1 functions as a modulator of Dishevelled nuclear localization in Wnt signaling.2013

Author(s)

Journal Title

Data Source

[Journal Article] Characterization of CXC-type chemokine molecules in early Xenopus laevis development.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IQGAP1 regulates nuclear localization of β-Catenin via importin-β5 in Wnt signaling.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IQGAP1 functions as a modulator of Dishevelled nuclear localization in Wnt signaling2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] WNK4 is an essential effector of anterior formation in FGF signaling2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IQGAP1 protein regulates nuclear localization of ・ -catenin via importin- ・ 5 in Wnt signaling2013

Author(s)

Journal Title

Data Source

[Presentation] beta-catenin の分解におけるWDR26 の機能解析2017

Author(s)

Organizer

Goto Toshiyasu 後藤利保

GOTO Toshiyasu 後藤利保

[Presentation] IQGAP1 によるβ-catenin の核内移行の調節機構の解析2013