IWASAWA Shunichiro 岩澤俊一郎

Researcher Number	00527913
Affiliation (based on the past Project Information) *help	2021: 千葉大学, 大学院医学研究院, 特任教授 2020: 千葉大学, 医学部附属病院, 講師 2017 – 2019: 千葉大学, 大学院医学研究院, 特任准教授 2017: 千葉大学, 医学(系)研究科(研究院), その他 2015 – 2016: 千葉大学, 医学部附属病院, 講師 2014: 千葉大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Respiratory surgery
Keywords	Principal Investigator AlphLISA / 悪性腫瘍 / AlphaLISA / 免疫チェックポイント阻害薬 / 自己抗体 / 免疫介在性有害事象 / cyclopamine / anti apoptosis / smoothened / Gli-2 … More / Gli-1 / neuroendocrine carcinoma / Gli2 / Gli1 / apoptosis / 神経内分泌がん / Smoothened / Sonic Hedgehog pathway … More Except Principal Investigator 薬剤耐性 / 化学療法 / 再生検 / トランスレーショナルリサーチ / 気管支鏡生検 / トランスレーショナル研究 / 超音波気管支鏡 / バイオマーカー / 肺癌 / 異常メチル化 / 微小乳頭型腺癌 / マスサイトメトリー解析 / 分子ステージング / 走査分子係数法 / 周波数特徴量解析 / 超音波気管支鏡ガイド下生検 / 呼吸器内視鏡 / 肺がん / プレシジョン医療 / 遺伝子発現 / インシュリン様増殖因子 / 増殖因子 / 耐性 / 悪性中皮腫 / ANKRD1 / AMPK / CARP / 薬物耐性 / ペメトレキセド / mTOR経路 / mTOR阻害薬 / metformin / PD-1 / がん / 上記間葉転換 / MET / nintedanib / pirfenidone / ピルフェニドン / ニンテダニブ / メトホルミン / EGFR / FGF / TGF / 上皮間葉移行 Less

Identification of Specific Autoantibodies for imAE by AlphaLISA assayPrincipal Investigator
- Principal Investigator
  
  IWASAWA Shunichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Chiba University
Development of diagnosis and treatment system using respiratory endoscopy to promote precision medicine
- Principal Investigator
  
  NAKAJIMA TAKAHIRO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Chiba University
Restoration of chemoresistance by modifying epithelial-to-mesenchymal transition.
- Principal Investigator
  
  Takiguchi Yuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Development of targeted therapy to overcome drug resistance in malignant mesothelioma
- Principal Investigator
  
  SEKINE Ikuo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tsukuba
  Chiba Cancer Center (Research Institute)
The exploration of the Hedgehog pathway as a treatment target in neuroendocrine carcinoma of the lung.Principal Investigator
- Principal Investigator
  
  IWASAWA Shunichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University

All 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] 免疫介在性有害事象（imAE）発症のリスク因子についての考察2020
- Author(s)
  岩澤俊一郎, 齋藤, 鹿野幸平, 日野葵
- Journal Title
  
  Precision Medicine
  
  Volume: 3 Pages: 97-101
- Data Source
  KAKENHI-PROJECT-19K07749
[Journal Article] ALK Rearrangement Adenocarcinoma with Histological Transformation to Squamous Cell Carcinoma Resistant to Alectinib and Ceritinib.2020
- Author(s)
  Kaiho T, Nakajima T, Iwasawa S, Yonemori Y, Yoshino I.
- Journal Title
  
  Onco Targets Ther.
  
  Volume: 13 Pages: 1557-1560
- DOI
  10.2147/ott.s236706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10774
[Journal Article] Intracardiac Tumors With Extracardiac Extension Diagnosed by Endoscopic Ultrasound With Bronchoscope-Guided Fine-Needle Aspiration2019
- Author(s)
  Inage Terunaga、Nakajima Takahiro、Sata Yuki、Fujiwara Taiki、Iwasawa Syunichiro、Takiguchi Yuichi、Nakatani Yukio、Yoshino Ichiro
- Journal Title
  
  The Annals of Thoracic Surgery
  
  Volume: 107 Issue: 1 Pages: e5-e7
- DOI
  10.1016/j.athoracsur.2018.05.046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10774, KAKENHI-PROJECT-17K09647
[Journal Article] A Repeated Biopsy by EBUS-TBNA Contributed to the Selection of an Appropriate Therapeutic Regimen for a Lung Cancer Patient2019
- Author(s)
  Naito, J. Toyoda, T. Nakajima, T. Fujiwara, T. Iwasawa, S. Suzuki, H. Takiguchi, Y. Yoshino, I.
- Journal Title
  
  J Bronchology Interv Pulmonol
  
  Volume: 26 Issue: 2 Pages: 129-131
- DOI
  10.1097/lbr.0000000000000571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09647, KAKENHI-PROJECT-17K10774
[Journal Article] Potential Activity of Amrubicin as a Salvage Therapy for Merkel Cell Carcinoma2017
- Author(s)
  Sakaida, E., Ebata, T., Iwasawa, S., Kurimoto, R., Yonemori, S., Ota, S., Nakatani, Y., Sekine, I. and Takiguchi, Y.
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 5 Pages: 567-570
- DOI
  10.2169/internalmedicine.56.7675
- NAID
  130005399427
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461182, KAKENHI-PROJECT-17K09647
[Journal Article] Pirfenidone may revert the epithelial-to-mesenchymal transition in human lung adenocarcinoma2017
- Author(s)
  Kurimoto, R., Ebata, T., Iwasawa, S., Ishiwata, T., Tada, Y,, Tatsumi, K and Takiguchi, y.
- Journal Title
  
  Oncol Rep
  
  Volume: 37
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Safety of a short hydration method for cisplatin administration in comparison with a conventional method―a retrospective study.2016
- Author(s)
  Sakaida, E., Iwasawa, S., Kurimoto, R., Ebata, T., Imai, C., Oku, T., Sekine, I., Tada, Y., Tatsumi, K. and Takiguchi, Y.
- Journal Title
  
  Japanese Journal of Clinical Oncology.
  
  Volume: 46 Issue: 4 Pages: 370-377
- DOI
  10.1093/jjco/hyv203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Drug resistance originating from a TGF-beta/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.2016
- Author(s)
  Kurimoto, R., Iwasawa, S., Ebata, T., Ishiwata, T., Sekine, I., Tada, Y., Tatsumi, K., Koide, S., Iwama, A. and Takiguchi, Y.
- Journal Title
  
  International journal of oncology
  
  Volume: 48 Issue: 5 Pages: 1825-1836
- DOI
  10.3892/ijo.2016.3419
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Prophylactic dexamethasone for radiation-induced bone-pain flare.2016
- Author(s)
  Ishiwata, T., Iwasawa, S., Kurimoto, R., Ebata, T. and Takiguchi, Y.
- Journal Title
  
  The Lancet. Oncology
  
  Volume: 17 Issue: 2 Pages: e39-e40
- DOI
  10.1016/s1470-2045(15)00622-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Crizotinib-Induced Abnormal Signal Processing in the Retina.2015
- Author(s)
  Ishii, T., Iwasawa, S., Kurimoto, R., Maeda, A., Takiguchi, Y. and Kaneda, M.
- Journal Title
  
  PloS one
  
  Volume: 10 Issue: 8 Pages: e0135521-e0135521
- DOI
  10.1371/journal.pone.0135521
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461182, KAKENHI-PROJECT-26860150
[Journal Article] Alveolar Hemorrhage Associated with Pemetrexed Administration2015
- Author(s)
  Kurimoto, R., Sekine, I., Iwasawa, S., Sakaida, E., Tada, Y., Tatsumi, K., Takahashi, Y., Nakatani, Y., Imai, C. and Takiguchi, Y.
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 7 Pages: 833-836
- DOI
  10.2169/internalmedicine.54.3414
- NAID
  130005063209
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Phase II study of carboplatin, docetaxel and bevacizumab for chemotherapy-naive patients with advanced non-squamous non-small cell lung cancer.2015
- Author(s)
  Takiguchi, Y., Iwasawa, S., Minato, K., Miura, Y., Gemma, A., Noro, R., Yoshimori, K., Shingyoji, M., Hino, M., Ando, M. and Okamoto, H.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 20 Issue: 4 Pages: 659-667
- DOI
  10.1007/s10147-014-0755-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182, KAKENHI-PROJECT-25461172
[Journal Article] Multicenter Phase II Study of Nedaplatin and Irinotecan for Patients with Squamous Cell Carcinoma of the Lung: Thoracic Oncology Research Group 0910.2015
- Author(s)
  YAMADA, K., SAITO, H., KONDO, T., MURAKAMI, S., MASUDA, N., YAMAMOTO, M., IGAWA, S., KATONO, K., TAKIGUCHI, Y., IWASAWA, S., KURIMOTO, R., OKAMOTO, H., SHIMOKAWA, T., HOSOMI, Y., TAKAGI, Y., KISHI, K., OHBA, M., OSHITA, F. and WATANABE, K.
- Journal Title
  
  Anticancer Research
  
  Volume: 35 Pages: 6705-6711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Incidence, risk factors and treatment outcomes of extravasation of cytotoxic agents in an outpatient chemotherapy clinic2014
- Author(s)
  Sakaida, E. Sekine, I. Iwasawa, S. Kurimoto, R. Uehara, T. Ooka, Y. Akanuma, N. Tada, Y. Imai, C. Oku, T. Takiguchi, Y.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 44 Issue: 2 Pages: 168-171
- DOI
  10.1093/jjco/hyt186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Chronic obstructive pulmonary disease as a risk factor for lung cancer2014
- Author(s)
  Takiguchi, Y. Sekine, I. Iwasawa, S. Kurimoto, R. Tatsumi, K.
- Journal Title
  
  World J Clin Oncol
  
  Volume: 5 Issue: 4 Pages: 660-666
- DOI
  10.5306/wjco.v5.i4.660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182
[Journal Article] Current Status of Medical Oncology in Japan―Reality Gleaned from a Questionnaire Sent to Designated Cancer Care Hospitals2014
- Author(s)
  Takiguchi, Y. Sekine, I. Iwasawa, S. Kurimoto, R. Sakaida, E. Tamura, K.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 44 Issue: 7 Pages: 632-640
- DOI
  10.1093/jjco/hyu059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461182
[Presentation] 肺腺癌再発に対する再生検の現状当院における治療成績向上のための取り組み2018
- Author(s)
  佐田諭己, 中島崇裕, 石綿司, 岩澤俊一郎, 寺田二郎, 坂入祐一, 田村創, 藤原大樹, 和田啓伸, 鈴木秀海, 山田義人, 千代雅子, 巽浩一郎, 吉野一郎.
- Organizer
  第41回日本呼吸器内視鏡学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10774
[Presentation] Alteration of drug sensitivity according to the induction and reversion of epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cell lines harboring an EGFR mutation2016
- Author(s)
  Kurimoto, R., Iwasawa, S., Ebata, T., Ishiwata, T., Sekine, I., Tada, Y., Tatsumi, K., Koide, S., Iwama, A. and Takiguchi, Y.
- Organizer
  2016 Annual Meeting: American Association for Cancer Research
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461182
[Presentation] Crizotinib disrupt visual processing in the mouse retina.2015
- Author(s)
  Ishii, T., Iwasawa, S., Kurimoto, R., Maeda, A., Takiguchi, Y. and Kaneda, M.
- Organizer
  Neuroscience 2015
- Place of Presentation
  McCormick Place (Chicago, USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461182

1. Takiguchi Yuichi (30272321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. SEKINE Ikuo (10508310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. NAKAJIMA TAKAHIRO (20400913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 田川雅敏 (20171572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 金田篤志 (10313024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 吉野一郎 (40281547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 本橋新一郎 (60345022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISHIWATA Tsukasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. EBATA Takahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWASAWA Shunichiro 岩澤 俊一郎

Research Projects

Research Products

Co-Researchers

Identification of Specific Autoantibodies for imAE by AlphaLISA assayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of diagnosis and treatment system using respiratory endoscopy to promote precision medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Restoration of chemoresistance by modifying epithelial-to-mesenchymal transition.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of targeted therapy to overcome drug resistance in malignant mesothelioma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The exploration of the Hedgehog pathway as a treatment target in neuroendocrine carcinoma of the lung.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 免疫介在性有害事象（imAE）発症のリスク因子についての考察2020

Author(s)

Journal Title

Data Source

[Journal Article] ALK Rearrangement Adenocarcinoma with Histological Transformation to Squamous Cell Carcinoma Resistant to Alectinib and Ceritinib.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intracardiac Tumors With Extracardiac Extension Diagnosed by Endoscopic Ultrasound With Bronchoscope-Guided Fine-Needle Aspiration2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Repeated Biopsy by EBUS-TBNA Contributed to the Selection of an Appropriate Therapeutic Regimen for a Lung Cancer Patient2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential Activity of Amrubicin as a Salvage Therapy for Merkel Cell Carcinoma2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Pirfenidone may revert the epithelial-to-mesenchymal transition in human lung adenocarcinoma2017

Author(s)

Journal Title

Data Source

[Journal Article] Safety of a short hydration method for cisplatin administration in comparison with a conventional method―a retrospective study.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drug resistance originating from a TGF-beta/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prophylactic dexamethasone for radiation-induced bone-pain flare.2016

Author(s)

Journal Title

DOI

Data Source

IWASAWA Shunichiro 岩澤俊一郎