• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

ISHIHARA Masahiro  石原 正浩

ORCIDConnect your ORCID iD *help
Researcher Number 00533803
Affiliation (based on the past Project Information) *help 2017 – 2019: 大阪大学, 医学系研究科, 招へい教員
2016: 大阪大学, 医学系研究科, 特任研究員
2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 特任研究員
2013: 大阪大学, 脳神経外科, 特任研究員
2012 – 2013: 大阪大学, 医学(系)研究科(研究院), 研究員 … More
2011: 大阪大学, 医学系・研究科, 特任研究員
2011: 大阪大学, 医学系研究科, 特任研究員
2010: 大阪大学, 医学部附属病院, 医員 Less
Review Section/Research Field
Principal Investigator
Neurosurgery / Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery
Keywords
Principal Investigator
脊髄損傷 / 神経再生 / 嗅粘膜 / 嗅粘膜移植 / 人工多能性幹細胞 / 幹細胞 / 細胞外マトリックス / 神経栄養因子 / 機能的結合 / 神経因性疼痛 … More / fMRI / 脊髄前角神経 / 廃用萎縮 / 嗅神経鞘細胞 / 神経前駆細胞 … More
Except Principal Investigator
細胞移動 / 軸索伸長 / 細胞外マトリックス / 嗅神経鞘細胞 / 抗L1CAM抗体 / 抗PSA-NCAM抗体 / VEGF / NGF / lamina propria / olfactory epithelium / 新生再生 / 嗅粘膜移植法 / 脊髄損傷 Less
  • Research Projects

    (5 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (5 People)
  •  Combined cell therapy using iPS derived neuron and olfactory mucosa for spinal cord injuryPrincipal Investigator

    • Principal Investigator
      Ishihara Masahiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Osaka University
  •  Functional connectivy after operation for spinal cord injuryPrincipal Investigator

    • Principal Investigator
      Ishihara Masahiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Osaka University
  •  New therapy for spinal cord injury focused on spinal anterior horn cellPrincipal Investigator

    • Principal Investigator
      ISHIHARA Masahiro
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Osaka University
  •  Development of implantable three-dimensional device with the induction of olfactory ensheathing cells with high axonal regeneration effect

    • Principal Investigator
      MORIWAKI takashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Osaka University
  •  Transplantation of multiple type of the cells derived from olfactory mucosa for the recovery of spinal cord injuryPrincipal Investigator

    • Principal Investigator
      ISHIHARA Masahiro
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Osaka University

All 2019 2018 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Analysis of cage stability and interbody pressure distribution in compression of cortical bone trajectory fixation2019

    • Author(s)
      Sho Fujiwar, Yu-ichiro Ohnishi, Hirofumi Sugano, Nobuhiko Nakajima, Asaya Nishi, Takashi Moriwaki, Masahiro Ishihara, Haruhiko Kishima,
    • Journal Title

      The Spine Journal

      Volume: 19(9) Issue: 9 Pages: S169-S170

    • DOI

      10.1016/j.spinee.2019.05.449

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10896
  • [Journal Article] Rupture of Internal carotid artery pseudoaneurysm in the sphenoid sinus as a complication of deep neck space infection2019

    • Author(s)
      Yoshiyuki Ozono, Suetaka Nishiike, Masahiro Ishihara, Toshiyuki Fujinaka
    • Journal Title

      J. Med. Invest.

      Volume: 66 Issue: 1.2 Pages: 188-189

    • DOI

      10.2152/jmi.66.188

    • NAID

      130007638803

    • ISSN
      1343-1420, 1349-6867
    • Year and Date
      2019-02-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10896
  • [Journal Article] A case of long-term survival after multimodal local treatments of intramedullary spinal cord metastasis of squamous cell lung cancer2016

    • Author(s)
      Minomo S, Tokoro A, Utsumi T, Ishihara M, Akira M, Atagi S.
    • Journal Title

      Journal of thoracic disease

      Volume: Aug;8(8) Issue: 8 Pages: 681-3

    • DOI

      10.21037/jtd.2016.06.58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462205
  • [Journal Article] A Pilot Clinical Study of Olfactory Mucosa Autograft for Chronic Complete Spinal Cord Injury2016

    • Author(s)
      Iwatsuki K1, Tajima F, Ohnishi Y, Nakamura T, Ishihara M, Hosomi K, Ninomiya K, Moriwaki T, Yoshimine T.
    • Journal Title

      Neurol. Med. Chir.(Tokyo)

      Volume: 56 Issue: 6 Pages: 285-292

    • DOI

      10.2176/nmc.oa.2015-0320

    • NAID

      130005157732

    • ISSN
      0470-8105, 1349-8029
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-16K10785
  • [Journal Article] Motor evoked potential and voluntary EMG activity after olfactory mucosal autograft transplantation in a case of chronic, complete spinal cord injury: case report2016

    • Author(s)
      Iwatsuki K, Tajima F, Sankai Y, Ohnishi YI, Nakamura T, Ishihara M, Hosomi K, Ninomiya K, Moriwaki T, Yoshimine T.
    • Journal Title

      Spinal cord series and cases

      Volume: Jan 7;2 Issue: 1 Pages: 15018-15018

    • DOI

      10.1038/scsandc.2015.18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-16K10785
  • [Journal Article] A Pilot Clinical Study of Olfactory Mucosa Autograft for Chronic Complete Spinal Cord Injury.2016

    • Author(s)
      Iwatsuki K, Tajima F, Ohnishi YI, Nakamura T, Ishihara M, Hosomi K, Ninomiya K, Moriwaki T, Yoshimine T.
    • Journal Title

      Neuroligia medico-chirurgica

      Volume: in press

    • NAID

      130005157732

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462205
  • [Journal Article] Isolation of human adult olfactory sphere cells as a cell source of neural progenitors.2015

    • Author(s)
      Ohnishi Y1, Iwatsuki K2, Ishihara M2, Shikina T3, Shinzawa K4, Moriwaki T2, Ninomiya K2, Ohkawa T2, Umegaki M2, Kishima H2, Yoshimine T2.
    • Journal Title

      Stem Cell Research

      Volume: 15(1) Issue: 1 Pages: 23-29

    • DOI

      10.1016/j.scr.2015.04.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-15K21134, KAKENHI-PROJECT-25462215
  • [Journal Article] Olfactory mucosa provides an optimal supporting tissue scaffold for neurite outgrowth via diffusible factors and cell-cell interaction2014

    • Author(s)
      Noriko Mochizuki-Oda, Masahiro Ishihara, Yu-ichiro Ohnishi, Takashi Moriwaki, Masao Umegaki, Koshi Ninomiya, Yumiko Iwamoto, Koichi Iwatsuki* and Toshiki Yoshimine
    • Journal Title

      Experimental Neurology

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659685
  • [Journal Article] Primary olfactory mucosal cells promote axonal outgrowth in a three-dimensional assay2014

    • Author(s)
      Ishihara M, Mochizuki-Oda N, Iwatsuki K, Kishima H, Ohnishi YI, Moriwaki T, Umegaki M, Yoshimine T
    • Journal Title

      J Neurosci Res

    • Data Source
      KAKENHI-PROJECT-24791498
  • [Journal Article] Primary olfactory mucosal cells promote axonal outgrowth in a three-dimensional assay2014

    • Author(s)
      Ishihara, Masahiro; Mochizuki-Oda, Noriko; Iwatsuki, Koichi et al.
    • Journal Title

      Journal of Neuroscience Research

      Volume: ahead of print Issue: 7 Pages: 270-4

    • DOI

      10.1002/jnr.23367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592124, KAKENHI-PROJECT-24791498, KAKENHI-PROJECT-24791500, KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-26462207
  • [Journal Article] Presence of trans-synaptic neurons derived from olfactory mucosa transplanted after spinal cord injury.2014

    • Author(s)
      Moriwaki T, Iwatsuki K, Mochizuki-Oda N, Ohnishi Y, Ishihara M, Umegaki M, Ninomiya K, Yoshimine T.
    • Journal Title

      Spine

      Volume: 15;39(16) Issue: 16 Pages: 1267-73

    • DOI

      10.1097/brs.0000000000000386

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-26861149
  • [Journal Article] Transplantation of Olfactory Mucosa as a Scaffold for Axonal Regeneration Following Spinal Cord Contusion in Rats2014

    • Author(s)
      Iwatsuki K, Yoshimine T, Sankai Y, Umegaki M, Ohnishi YI, Ishihara M, Moriwaki T, Oda N
    • Journal Title

      Neuroscience & Medicine

      Volume: 4(2)

    • Data Source
      KAKENHI-PROJECT-24791498
  • [Journal Article] Presence of trans-synaptic neurons derived from olfactory mucosa transplanted after spinal cord injury2014

    • Author(s)
      Takashi Moriwaki, Koichi Iwatsuki, Noriko Mochizuki-Oda, Yu-ichiro Ohnishi, Masahiro Ishihara, Masao Umegaki, Koshi Ninomiya and Toshiki Yoshimine
    • Journal Title

      Spine

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659685
  • [Journal Article] Involuntary muscle spasm expressed as motor evoked potential after olfactory mucosa autograft in patients with chronic spinal cord injury and complete paraplegia2013

    • Author(s)
      Koichi Iwatsuki, Toshiki Yoshimine et al.
    • Journal Title

      J. Biomedical Science and Engineering,

      Volume: 6 Issue: 09 Pages: 908-916

    • DOI

      10.4236/jbise.2013.69111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592124, KAKENHI-PROJECT-24791498
  • [Journal Article] Adult olfactory sphere cells are a source of oligodendrocyte and Schwann cell progenitors.2013

    • Author(s)
      Ohnishi Y, Iwatsuki K et al.
    • Journal Title

      Stem Cell Research

      Volume: 11 Issue: 3 Pages: 1178-1190

    • DOI

      10.1016/j.scr.2013.08.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592124, KAKENHI-PROJECT-24791498, KAKENHI-PROJECT-25462215
  • [Journal Article] Involuntary muscle spasm expressed as motor evoked potential after olfactory mucosa autograft in patients with chronic spinal cord injury and complete paraplegia2013

    • Author(s)
      Iwatsuki K, Yoshimine T, Sankai Y, Tajima F, Ishihara M, et al
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: (6) Pages: 9-9

    • Data Source
      KAKENHI-PROJECT-24791498
  • [Journal Article] Adult olfactory sphere cells are a source of oligodendrocyte and Schwann cell progenitors2013

    • Author(s)
      Ohnishi YI, Iwatsuki K, Shinzawa K, Ishihara M, Moriwaki T, Umegaki M, Kishima H, Yoshimine T
    • Journal Title

      Stem Cell Research

      Volume: 15;11(3) Pages: 1178-1190

    • Data Source
      KAKENHI-PROJECT-24791498
  • [Journal Article] Transplantation of olfactory mucosa as a scaffold for axonal regeneration following spinal cord contusion in rats.2013

    • Author(s)
      Koichi Iwatsuki et al.
    • Journal Title

      Neuroscience & Medicine

      Volume: 4 Issue: 02 Pages: 112-116

    • DOI

      10.4236/nm.2013.42018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592124, KAKENHI-PROJECT-24791498
  • [Journal Article] Intradural extramedullary spinal ependymoma: a case report of malignant transformation occurring2013

    • Author(s)
      Takashi Moriwaki, Koichi Iwatsuki ,Masahiro Ishihara
    • Journal Title

      Asian Spine Journal

      Volume: 2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791498
  • [Journal Article] Disuse muscle atrophy exacerbates motor neuronal degeneration caudal to the site of spinal cord injury2012

    • Author(s)
      Ohnishi Y, Iwatsuki K, Shinzawa K, Nakai Y, Ishihara M, Yoshimine T
    • Journal Title

      Neuroreport

      Volume: 15;23(3) Pages: 157-61

    • Data Source
      KAKENHI-PROJECT-24791498
  • [Journal Article] Disuse muscle atrophy exacerbates motor neuronal degeneration caudal to the site of spinal cord injury2012

    • Author(s)
      Ohnishi Y, Iwatsuki K, Shinzawa K, Nakai Y, Ishihara M, Yoshimine T
    • Journal Title

      Neuroreport

      Volume: 23 Pages: 157-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Journal Article] Histopathological Study of Spinal Meningioma Originating from Arachnoid Villi : A Case Report2011

    • Author(s)
      Yu-ichiro Ohnishi, Koichi Iwatsuki, Eiichi Morii, Maki Kobayashi, Yumiko Hori, Takashi Moriwaki, Masahiro Ishihara, Kazunori Yoshimura, Masao Umegaki and Toshiki Yoshimine
    • Journal Title

      Brain Tumor Phathol

      Volume: 28 Pages: 77-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Journal Article] A new three-dimensional axonal outgrowth assay for central nervous system regeneration2011

    • Author(s)
      M. Ishihara et al
    • Journal Title

      Journal of Neuroscience Methods

      Volume: 198 Pages: 181-186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Journal Article] Percutaneous Diode Laser Irradiation for Lumber Discogenic Pain : A Clinical Study2011

    • Author(s)
      Iwatsuki K, Yoshimine T, Umegaki M, Yoshimura K, Ohnishi Y, Ishihara M, Moriwaki T
    • Journal Title

      Photomedicine and Laser Surgery

      Volume: 29 Pages: 459-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] Olfactory mucosa provides an optimal supporting tissue for neurite outgrowth via diffusible factors and cell-cell interaction2018

    • Author(s)
      Masahiro Ishihara, Noriko Mochizuki-Oda, Yu-ichiro Ohnishi, Koichi Iwatsuki, and Haruhiko Kishima
    • Organizer
      ASIA SPINE 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10896
  • [Presentation] 嗅粘膜組織による神経軸索誘引効果の検討2015

    • Author(s)
      石原正浩、小田紀子、岩月幸一、二宮貢士、森脇祟、吉峰俊樹
    • Organizer
      第30日本脊髄外科学会
    • Place of Presentation
      北海道立道民活動センターかでる2.7
    • Year and Date
      2015-06-25
    • Data Source
      KAKENHI-PROJECT-26462205
  • [Presentation] 廃用性萎縮は脊髄損傷尾側での運動神経ニューロン変性を増悪させる.2012

    • Author(s)
      大西論一朗 岩月幸一, 新沢康英, 石原正浩, 吉峰俊樹
    • Organizer
      第27回日本脊髄外科学会
    • Place of Presentation
      浦安
    • Year and Date
      2012-06-21
    • Data Source
      KAKENHI-PROJECT-24791498
  • [Presentation] 脊髄損傷に対する嗅粘膜移植術2012

    • Author(s)
      石原正浩
    • Organizer
      第71回日本脳神経外科学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24791498
  • [Presentation] 廃用性筋萎縮は脊髄損傷尾側での運動ニューロン変性を増悪させる2012

    • Author(s)
      大西諭一郎、岩月幸一、新沢康英、石原正浩、吉峰俊樹
    • Organizer
      第27回日本脊髄外科学会
    • Place of Presentation
      浦安
    • Data Source
      KAKENHI-PROJECT-24791498
  • [Presentation] 脊髄損傷に対する嗅粘膜移植術2012

    • Author(s)
      石原 正浩
    • Organizer
      第71回日本脳神経外科学会
    • Year and Date
      2012-10-17
    • Data Source
      KAKENHI-PROJECT-24791498
  • [Presentation] 嗅粘膜由来細胞の持つ神経軸索再生効果についての検討~in vitro 3次元培養系を用いて~2011

    • Author(s)
      石原正浩
    • Organizer
      第69回脳神経外科学会総会
    • Place of Presentation
      マリンメッセ福岡
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] 初代嗅粘膜由来細胞の神経栄養因子分泌能および形態変化についての検討2011

    • Author(s)
      石原正浩
    • Organizer
      第26回脊髄外科学会
    • Place of Presentation
      沼津市民文化センター
    • Year and Date
      2011-06-10
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] Olfactory mucosal cells promote axonal regeneration in newly three-dimensional assay2011

    • Author(s)
      M Ishihara
    • Organizer
      Neuroscience 2011, SfN' s 41st annual meeting : November 14^<th>
    • Place of Presentation
      Washington D. C.(USA)
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] Olfactory mucosal cells promote axonal regeneration in newly three-dimensional assay2011

    • Author(s)
      M Ishihara, et al
    • Organizer
      Neuroscience 2011, SfN's 41st annual meeting
    • Place of Presentation
      Washington D.C.(USA)
    • Year and Date
      2011-11-14
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] 嗅粘膜由来細胞の神経栄養因子分泌能およびその形態変化についての検討2011

    • Author(s)
      石原正浩
    • Organizer
      第70回脳神経外科学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-10-12
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] Regeneration of cortical axons into the three-dimensional gel containing olfactory cells.2010

    • Author(s)
      Masahiro Ishihara
    • Organizer
      8^<th> International Society for Stem Cell Research
    • Place of Presentation
      Moscon convention center(USA)
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] 3次元ゲルアッセイ系を用いた嗅粘膜由来細胞の持つ神経軸索再生効果の検討2010

    • Author(s)
      石原正浩
    • Organizer
      第25回日本脊髄外科学会総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2010-06-09
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] 大脳皮質-Matrigel共培養アッセイ系を用いた嗅粘膜由来細胞の持つ神経軸索再生効果の検討2010

    • Author(s)
      石原正浩
    • Organizer
      第25回神経組織の成長・再生・移植研究会
    • Place of Presentation
      大阪市立大学
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] Olfactory mucosal cells promote axonal regeneration in a newly developed vitro model.2010

    • Author(s)
      Masahiro Ishihara
    • Organizer
      Asia Pacific Symposium on Neural Regeneration
    • Place of Presentation
      Yonsei University(Korea)
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] Regeneration of cortical axons into the three-dimensional gel containing olfactory cells2010

    • Author(s)
      M Ishihara
    • Organizer
      International Society for Stem Cell Research 8^<th> annual meeting 16^<th>
    • Place of Presentation
      San Franscisco(USA)
    • Data Source
      KAKENHI-PROJECT-22791342
  • [Presentation] 嗅粘膜由来細胞の持つ神経軸索再生効果についての検討~in vitro 3次元培養系を用いて~2010

    • Author(s)
      石原正浩
    • Organizer
      脳神経外科学会第69回学術総会
    • Place of Presentation
      福岡コンベンションセンター
    • Year and Date
      2010-10-27
    • Data Source
      KAKENHI-PROJECT-22791342
  • 1.  IWATSUKI Koichi (80346204)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 2.  MORIWAKI takashi (20591019)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  YOSHIMINE Toshiki (00201046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  UMEGAKI Masao (30448063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  OHNISHI Yuichiro (00533811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi