Ohnishi Yuichiro 大西諭一郎

… Alternative Names

OHNISHI Yuichiro 大西諭一郎

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Researcher Number	00533811
Other IDs	https://orcid.org/0000-0003-3030-6230
Affiliation (Current)	2026: 国立研究開発法人国立循環器病研究センター, 研究所, 室長
Affiliation (based on the past Project Information) *help	2026: 国立研究開発法人国立循環器病研究センター, 研究所, 非常勤研究員 2021 – 2024: 国立研究開発法人国立循環器病研究センター, 研究所, 非常勤研究員 2016 – 2020: 大阪大学, 医学系研究科, 助教 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2013: 大阪大学, 脳神経外科, 医員 2011 – 2013: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Cerebral neurosurgery Except Principal Investigator Neurosurgery / Cerebral neurosurgery
Keywords	Principal Investigator 脊髄損傷 / 嗅粘膜 / degeneration / spinal cord injury / ATP / 代謝 / ニューロン / オリゴデンドロサイト / オルファクトリースフィア / エネルギー … More / 神経変性 / ワーラー変性 / 末梢神経損傷 / ミトコンドリア / mitochondria / metabolic stress / energy / neuron / 脊髄 / 脳 / 神経 / アデノシン三リン酸 / 急性期 / oxidative stress / glycolysis / metabolism / 酸化ストレス / 軸索変性 / 解糖系 / 脊髄・脊椎疾患 / オルファクトリースフィア細胞 / 嗅粘膜組織 / 神経前駆細胞 / シュワン細胞 / GABAニューロン / オリゴデンドロサイト前駆細胞 / 神経幹細胞 / 分化 / 幹細胞 … More Except Principal Investigator 脊髄損傷 / neuronal relay formation / relay neurons / 神経軸索再生 / 慢性期脊髄損傷 / 神経栄養因子 / fMRI / spinal DTI / 嗅粘膜移植 / relay neuron / 細胞移動 / 軸索伸長 / 細胞外マトリックス / 嗅神経鞘細胞 / 抗L1CAM抗体 / 抗PSA-NCAM抗体 / VEGF / NGF / lamina propria / olfactory epithelium / 新生再生 / 嗅粘膜移植法 Less

経ニューロン変性に対する前角ニューロン選択的ミトコンドリア移植の分子機構の解明Principal Investigator
- Principal Investigator
  
  大西諭一郎
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Cardiovascular Center Research Institute
Energy metabolism in neuronal degeneration at the caudal site of spinal cord injuryPrincipal Investigator
- Principal Investigator
  
  Yuichiro Ohnishi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Cardiovascular Center Research Institute
Real-time monitoring of intracellular ATP concentration in acute spinal cord injuryPrincipal Investigator
- Principal Investigator
  
  Ohnishi Yuichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Cardiovascular Center Research Institute
  Osaka University
Application of human adult olfactory sphere cells as a cell source for treatment of spinal cord injuryPrincipal Investigator
- Principal Investigator
  
  Ohnishi Yu-ichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka University
Evaluation of co-transplantation method between olfactory mucosa transplantation method and bone marrow mesenchymal cell medulla injection therapy
- Principal Investigator
  
  Moriwaki Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka University
Development of regenerative medicine by oligodendrocyte and schwann precursor cellsPrincipal Investigator
- Principal Investigator
  
  Ohnishi Yuichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka University
Development of implantable three-dimensional device with the induction of olfactory ensheathing cells with high axonal regeneration effect
- Principal Investigator
  
  MORIWAKI takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka University
Adult Olfactory Sphere Cells are aSource of Oligodendrocyte and Schwann Cell ProgenitorsPrincipal Investigator
- Principal Investigator
  
  OHNISHI Yu-ichiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka University

[Book] 脊椎脊髄ジャーナル2013
- Author(s)
  大西諭一郎
- Total Pages
  5
- Publisher
  三輪書店
- Data Source
  KAKENHI-PROJECT-25462215
[Book] 脊髄損傷慢性期に対する嗅粘膜移植法2011
- Author(s)
  大西諭一郎、岩月幸一、吉峰俊樹
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] Excess Intracellular ATP Causes Neuropathic Pain Following Spinal Cord Injury2024
- Author(s)
  大西諭一郎
- Journal Title
  
  Spinal Surgery
  
  Volume: 38 Issue: 2 Pages: 158-160
- DOI
  10.2531/spinalsurg.38.158
- ISSN
  0914-6024, 1880-9359
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09248
[Journal Article] Glycolytic System in Axons Supplement Decreased ATP Levels after Axotomy of the Peripheral Nerve.2023
- Author(s)
  Tomofumi Takenaka , Yuichiro Ohnishi , Masamichi Yamamoto , Daiki Setoyama , Haruhiko Kishima
- Journal Title
  
  eNeuro
  
  Volume: 10 Issue: 3 Pages: 0353-22
- DOI
  10.1523/eneuro.0353-22.2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09248, KAKENHI-PROJECT-19H03561, KAKENHI-PROJECT-20K17967
[Journal Article] White matter microstructural alterations in patients with neuropathic pain after spinal cord injury: a diffusion tensor imaging study2023
- Author(s)
  Dong Dong、Hosomi Koichi、Mori Nobuhiko、Kamijo Yoshi-ichiro、Furotani Yohei、Yamagami Daisuke、Ohnishi Yu-ichiro、Watanabe Yoshiyuki、Nakamura Takeshi、Tajima Fumihiro、Kishima Haruhiko、Saitoh Youichi
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 14 Pages: 1241658-1241658
- DOI
  10.3389/fneur.2023.1241658
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09206, KAKENHI-PROJECT-22K09248, KAKENHI-PROJECT-23K08519, KAKENHI-PROJECT-23K10559
[Journal Article] The SGLT2 inhibitor empagliflozin improves cardiac energy status via mitochondrial ATP production in diabetic mice.2023
- Author(s)
  Jungmi Choi, Naoki Matoba, Daiki Setoyama, Daiki Watanabe, Yuichiro Ohnishi, Ryuto Yasui, Yuichirou Kitai, Aki Oomachi, Yutaro Kotobuki, Yoichi Nishiya, Michael Paul Pieper, Hiromi Imamura, Motoko Yanagita, Masamichi Yamamoto
- Journal Title
  
  Communications Biology
  
  Volume: 278 Issue: 1 Pages: 278-278
- DOI
  10.1038/s42003-023-04663-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09248, KAKENHI-PROJECT-19H03561, KAKENHI-PROJECT-22K08150
[Journal Article] 神経損傷でのエネルギー代謝と軸索変性2023
- Author(s)
  大西諭一郎、竹中朋文、山本正道
- Journal Title
  
  細胞
  
  Volume: 55 Pages: 846-849
- Data Source
  KAKENHI-PROJECT-22K09248
[Journal Article] Tentorial Dural Arteriovenous Fistula Presenting with Venous Congestive Edema of the Upper Cervical Cord2022
- Author(s)
  Yuichiro OHNISHI , Tomofumi TAKENAKA , Sho FUJIWARA
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 9 Issue: 0 Pages: 193-198
- DOI
  10.2176/jns-nmc.2022-0014
- ISSN
  2188-4226
- Year and Date
  2022-12-31
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09248
[Journal Article] Cortical bone trajectory fixation cause low compression force in anterior vertebral column2022
- Author(s)
  Sho Fujiwara , Yuichiro Ohnishi , Koichi Iwatsuki , Haruhiko Kishima
- Journal Title
  
  North American Spine Society Journal (NASSJ)
  
  Volume: 10 Pages: 100113-100113
- DOI
  10.1016/j.xnsj.2022.100113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09248
[Journal Article] Tight adhesions after spinal cord stimulation observed during dorsal root entry zone lesioning for pain after spinal root avulsion: illustrative cases.2022
- Author(s)
  Yuki Kimoto , Koichi Hosomi , Yuichiro Ohnishi , Takuto Emura , Nobuhiko Mori , Asaya Nishi , Takufumi Yanagisawa , Naoki Tani , Satoru Oshino , Youichi Saitoh , Haruhiko Kishima
- Journal Title
  
  Journal of neurosurgery. Case lessons
  
  Volume: 4 Issue: 17 Pages: 4-4
- DOI
  10.3171/case22145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09248, KAKENHI-PROJECT-19K19867, KAKENHI-PROJECT-18H04085
[Journal Article] 脊髄損傷頭尾側でのエネルギー代謝と軸索変性の違い2022
- Author(s)
  大西諭一郎
- Journal Title
  
  脊髄外科
  
  Volume: 36 Pages: 306-308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09248
[Journal Article] Excess intracellular ATP causes neuropathic pain following spinal cord injury2022
- Author(s)
  Nobuhiko Nakajima , Yuichiro Ohnishi , Masamichi Yamamoto , Daiki Setoyama , Hirohiko Imai , Tomofumi Takenaka , Mari Matsumoto , Koichi Hosomi , Yoichi Saitoh , Hidemasa Furue , Haruhiko Kishima
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 79 Issue: 9 Pages: 483-483
- DOI
  10.1007/s00018-022-04510-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09248, KAKENHI-PROJECT-20H04043, KAKENHI-PROJECT-18H04085
[Journal Article] 脊髄損傷後神経障害性疼痛の評価、診断、治療2022
- Author(s)
  大西諭一郎
- Journal Title
  
  脊髄外科
  
  Volume: 36 Pages: 12-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09248
[Journal Article] Mass Spectrometric Enzyme Histochemistry for Choline Acetyltransferase Reveals <i>De Novo</i> Acetylcholine Synthesis in Rodent Brain and Spinal Cord2021
- Author(s)
  Takeo Emi、Sugiura Yuki、Ohnishi Yuichiro、Kishima Haruhiko、Fukusaki Eiichiro、Shimma Shuichi
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 12 Issue: 12 Pages: 2079-2087
- DOI
  10.1021/acschemneuro.0c00720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09527
[Journal Article] An increase in the posterior subarachnoid space accelerates the timing of syrinx resolution after foramen magnum decompression of type I Chiari malformation2021
- Author(s)
  Ohnishi Yuichiro、Fujiwara Sho、Takenaka Tomofumi、Kawamoto Saki、Iwatsuki Koichi、Kishima Haruhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 19152-19152
- DOI
  10.1038/s41598-021-98546-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09527, KAKENHI-PROJECT-18H04085
[Journal Article] Rostro-caudal different energy metabolism leading to differences in degeneration in spinal cord injury2021
- Author(s)
  Ohnishi Yuichiro、Yamamoto Masamichi、Sugiura Yuki、Setoyama Daiki、Kishima Haruhiko
- Journal Title
  
  Brain Communications
  
  Volume: 3 Issue: 2
- DOI
  10.1093/braincomms/fcab058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09527, KAKENHI-PROJECT-19K22513, KAKENHI-PROJECT-19H03561
[Journal Article] Conservative and Surgical Management of Spinal Cord Cavernous Malformations.2019
- Author(s)
  Ohnishi YI, Nakajima N, Takenaka T, Fujiwara S, Miura S, Terada E, Yamada S, Kishima H.
- Journal Title
  
  World Neurosurg X.
  
  Volume: 5 Pages: 100066-100066
- DOI
  10.1016/j.wnsx.2019.100066
- NAID
  130007904678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09527, KAKENHI-PROJECT-18H04085
[Journal Article] Sufficient Surgical Window for Deep-Seated Extracranial Schwannomas in the Craniocervical Junction by the Anterolateral Approach.2019
- Author(s)
  Ohnishi YI, Nakajima N, Fujiwara S, Moriwaki T, Arita H, Kishima H.
- Journal Title
  
  Neurospine.
  
  Volume: 4 Issue: 2 Pages: 4-4
- DOI
  10.14245/ns.1938270.135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09527
[Journal Article] Automatic diagnosis of neurological diseases using MEG signals with a deep neural network.2019
- Author(s)
  Aoe J, Fukuma R, Yanagisawa T, Harada T, Tanaka M, Kobayashi M, Inoue Y, Yamamoto S, Ohnishi Y, Kishima H.
- Journal Title
  
  Sci Rep.
  
  Volume: 9(1) Issue: 1 Pages: 5057-5057
- DOI
  10.1038/s41598-019-41500-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09527, KAKENHI-PLANNED-18H05522, KAKENHI-PROJECT-18H04085, KAKENHI-PUBLICLY-17H06032
[Journal Article] Promotion of astrocytoma cell invasion by micro RNA-22 targeting of tissue inhibitor of matrix metalloproteinase-22017
- Author(s)
  Ohnishi YI, Iwatsuki K, Ishihara M, Ohkawa T, Kinoshita M, Shinzawa K, Fujimoto Y, Yoshimine T.
- Journal Title
  
  J Neurosurg Spine
  
  Volume: 26(3) Issue: 3 Pages: 396-403
- DOI
  10.3171/2016.8.spine16248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21134, KAKENHI-PROJECT-16K10785
[Journal Article] A Pilot Clinical Study of Olfactory Mucosa Autograft for Chronic Complete Spinal Cord Injury2016
- Author(s)
  Iwatsuki K1, Tajima F, Ohnishi Y, Nakamura T, Ishihara M, Hosomi K, Ninomiya K, Moriwaki T, Yoshimine T.
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 56 Issue: 6 Pages: 285-292
- DOI
  10.2176/nmc.oa.2015-0320
- NAID
  130005157732
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-16K10785
[Journal Article] Significance of the Pars Interarticularis in the Cortical Bone Trajectory Screw Technique: An In Vivo Insertional Torque Study.2016
- Author(s)
  Ninomiya K, Iwatsuki K, Ohnishi YI, Ohkawa T, Yoshimine T.
- Journal Title
  
  Asian Spine J.
  
  Volume: 10(5) Pages: 901-906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10785
[Journal Article] Radiological Evaluation of the Initial Fixation between Cortical Bone Trajectory and Conventional Pedicle Screw Technique for Lumbar Degenerative Spondylolisthesis.2016
- Author(s)
  Ninomiya K, Iwatsuki K, Ohnishi Y, Yoshimine T.
- Journal Title
  
  Asian Spine J.
  
  Volume: 10(2) Issue: 2 Pages: 251-7
- DOI
  10.4184/asj.2016.10.2.251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10785
[Journal Article] Motor evoked potential and voluntary EMG activity after olfactory mucosal autograft transplantation in a case of chronic, complete spinal cord injury: case report2016
- Author(s)
  Iwatsuki K, Tajima F, Sankai Y, Ohnishi YI, Nakamura T, Ishihara M, Hosomi K, Ninomiya K, Moriwaki T, Yoshimine T.
- Journal Title
  
  Spinal cord series and cases
  
  Volume: Jan 7;2 Issue: 1 Pages: 15018-15018
- DOI
  10.1038/scsandc.2015.18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-16K10785
[Journal Article] A case of T2 radiculopathy after anterior C5-6 fusion.2016
- Author(s)
  Takenaka T, Ohnishi YI, Oshino S.
- Journal Title
  
  Journal of Surgical Case report.
  
  Volume: 2016(5) Issue: 5 Pages: 5-5
- DOI
  10.1093/jscr/rjw098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10785
[Journal Article] Isolation of human adult olfactory sphere cells as a cell source of neural progenitors.2015
- Author(s)
  Ohnishi Y1, Iwatsuki K2, Ishihara M2, Shikina T3, Shinzawa K4, Moriwaki T2, Ninomiya K2, Ohkawa T2, Umegaki M2, Kishima H2, Yoshimine T2.
- Journal Title
  
  Stem Cell Research
  
  Volume: 15(1) Issue: 1 Pages: 23-29
- DOI
  10.1016/j.scr.2015.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-15K21134, KAKENHI-PROJECT-25462215
[Journal Article] Olfactory sphere cells are a cell source for γ-aminobutyric acid-producing neurons.2015
- Author(s)
  Ohnishi YI, Maruo T, Shinzawa K, Iwatsuki K, Moriwaki T, Oshino S, Kishima H, YoshimineT
- Journal Title
  
  J Neurosci Res. 2
  
  Volume: 93 Issue: 8 Pages: 1293-1304
- DOI
  10.1002/jnr.23585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462208, KAKENHI-PROJECT-25462215
[Journal Article] Olfactory mucosa provides an optimal supporting tissue scaffold for neurite outgrowth via diffusible factors and cell-cell interaction2014
- Author(s)
  Noriko Mochizuki-Oda, Masahiro Ishihara, Yu-ichiro Ohnishi, Takashi Moriwaki, Masao Umegaki, Koshi Ninomiya, Yumiko Iwamoto, Koichi Iwatsuki* and Toshiki Yoshimine
- Journal Title
  
  Experimental Neurology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659685
[Journal Article] A case of intrapelvic sciatic nerve schwannoma presenting as piriformis syndrome.2014
- Author(s)
  1. Ninomiya K, Iwatsuki K, Ohnishi Y, Moriwaki T, Yoshimine T.
- Journal Title
  
  Journal of Neuroscinece and Behavioural Health.
  
  Volume: 6 Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462215
[Journal Article] Presence of trans-synaptic neurons derived from olfactory mucosa transplanted after spinal cord injury2014
- Author(s)
  Takashi Moriwaki, Koichi Iwatsuki, Noriko Mochizuki-Oda, Yu-ichiro Ohnishi, Masahiro Ishihara, Masao Umegaki, Koshi Ninomiya and Toshiki Yoshimine
- Journal Title
  
  Spine
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659685
[Journal Article] Presence of trans-synaptic neurons derived from olfactory mucosa transplanted after spinal cord injury.2014
- Author(s)
  Moriwaki T, Iwatsuki K, Mochizuki-Oda N, Ohnishi Y, Ishihara M, Umegaki M, Ninomiya K, Yoshimine T.
- Journal Title
  
  Spine
  
  Volume: 15;39(16) Issue: 16 Pages: 1267-73
- DOI
  10.1097/brs.0000000000000386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-26861149
[Journal Article] Transplantation of Olfactory Mucosa as a Scaffold for Axonal Regeneration Following Spinal Cord Contusion in Rats.2013
- Author(s)
  5. Iwatsuki K, Yoshimine T, Sankai Y, Umegaki M, Ohnishi Y, Ishihara M, Moriwaki T and Oda N.
- Journal Title
  
  Neuroscience & Medicine.
  
  Volume: 4 Pages: 112-116
- Data Source
  KAKENHI-PROJECT-25462215
[Journal Article] Intradural extramedullary spinal ependymoma: a case report of malignant transformation occurring2013
- Author(s)
  Takashi Moriwaki, Koichi Iwatsuki, Yu-ichiro Ohnishi,
- Journal Title
  
  Asian Spine Journal
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659685
[Journal Article] Adult olfactory sphere cells are a source of oligodendrocyte and Schwann cell progenitors.2013
- Author(s)
  Ohnishi Y, Iwatsuki K et al.
- Journal Title
  
  Stem Cell Research
  
  Volume: 11 Issue: 3 Pages: 1178-1190
- DOI
  10.1016/j.scr.2013.08.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592124, KAKENHI-PROJECT-24791498, KAKENHI-PROJECT-25462215
[Journal Article] Involuntary muscle spasm expressed as motor evoked potential after olfactory mucosa autograft in patients with chronic spinal cord injury and complete paraplegia.2013
- Author(s)
  4. Iwatsuki K, Yoshimine T, Sankai Y, Tajima F, Umegaki M, Ohnishi Y, Ishihara M, Ninomiya K and Moriwaki T.
- Journal Title
  
  Journal of Biomedical Science and Engineering.
  
  Volume: 6 Pages: 908-916
- Data Source
  KAKENHI-PROJECT-25462215
[Journal Article] Intradural extramedullary spinal ependymoma: a case report of malignant transformation occurring.2013
- Author(s)
  7. Moriwaki T, Iwatsuki K, Ohnishi Y, Umegaki M, Ishihara M, Yoshimine T.
- Journal Title
  
  Asian Spine Journal
  
  Volume: 7 Issue: 2 Pages: 139-42
- DOI
  10.4184/asj.2013.7.2.139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462215
[Journal Article] Disuse muscle atrophy exacerbates motor neuronal degeneration caudal to the site of spinal cord injury2012
- Author(s)
  Ohnishi Y, Iwatsuki K, Shinzawa K, Nakai Y, Ishihara M, Yoshimine T
- Journal Title
  
  Neuroreport.
  
  Volume: 23(3) Pages: 157-61
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] Transient total mesencephalic locked-in syndrome after bilateral ptosis due to basilar artery thrombosis2012
- Author(s)
  Fujimoto Y, Ohnishi Y, Wakayama A, Yoshimine T
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 21(8)
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] Entrapment of the Fifth Lumbar Spinal Nerve by Advanced Osteophytic Changes of the Lumbosacral Zygapophyseal Joint2012
- Author(s)
  Yu-ichiro Ohnishi
- Journal Title
  
  Asian Spine Journal
  
  Volume: 6 Pages: 291-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] Entrapment of the fifth lumbar spinal nerve by advanced osteophytic changes of the lumbosacral zygapophyseal joint: a case report2012
- Author(s)
  Ohnishi Y, Yuguchi T, Iwatsuki K, Yoshimine T
- Journal Title
  
  Asian Spine J
  
  Volume: 6(4) Pages: 291-3
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] Disuse muscle atrophy exacerbates motor neuronal degeneration caudal to the site of spinal cord injury2012
- Author(s)
  Yu-ichiro Ohnishi
- Journal Title
  
  Neuroreport
  
  Volume: 23 Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] A new three-dimensional axonal outgrowth assay for central nervous system regeneration2011
- Author(s)
  Ishihara M, Mochizuki-Oda N, Iwatsuki K, Kishima H, Iwamoto Y, Ohnishi Y,Umegaki M, Yoshimine T
- Journal Title
  
  J Neurosci Methods
  
  Volume: 198(2) Pages: 181-6
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] Histopathological study of spinal meningioma originating from the arachnoid villi2011
- Author(s)
  Ohnishi Y, Iwatsuki K, Morii E, Kobayashi M, Hori Y, Moriwaki T, Ishihara M,Yoshimura K, Umegaki M, Yoshimine T
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 28(1) Pages: 77-81
- Data Source
  KAKENHI-PROJECT-23791596
[Journal Article] Percutaneous diode laser irradiation for lumbar discogenic pain: a clinical study2011
- Author(s)
  Iwatsuki K, Yoshimine T, Umegaki M, Yoshimura K, Ohnishi Y, Ishihara M, Moriwaki T.
- Journal Title
  
  Photomed Laser Surg
  
  Volume: 29(7) Pages: 459-63
- Data Source
  KAKENHI-PROJECT-23791596
[Patent] 神経・軸索変性の予防または治療剤、ならびに神経賦活剤2024
- Inventor(s)
  大西諭一郎、山本正道
- Industrial Property Rights Holder
  大西諭一郎、山本正道
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-064711
- Filing Date
  2024
- Overseas
- Data Source
  KAKENHI-PROJECT-22K09248
[Patent] オルファクトリースフィア細胞の生成・単離方法及び製造方法並びに該オルファクトリースフィア細胞を用いた脱随疾患治療剤及び末梢神経軸索再生増強剤の製造方法2017
- Inventor(s)
  大西諭一郎
- Industrial Property Rights Holder
  大西諭一郎
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-16K10785
[Patent] オルファクトリースフィア細胞の単離方法、該オルファクトリースフィア細胞を用いた脱髄疾患治療剤及び末梢神経軸索再生増強剤の製造方法2012
- Inventor(s)
  大西諭一郎
- Industrial Property Rights Holder
  大西諭一郎
- Industrial Property Rights Type
  特許
- Filing Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23791596
[Patent] オルファクトリースフィア細胞の単離方法、該オルファクトリースフィア細胞を用いた脱髄疾患治療剤及び末梢神経軸索再生増強剤の製造方法2012
- Inventor(s)
  大西諭一郎
- Industrial Property Rights Holder
  大西諭一郎
- Filing Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23791596
[Presentation] Prevention of caudal axonal degeneration in spinal cord injury by mitochondrial transfer2024
- Author(s)
  Yuichiro Ohnishi
- Organizer
  Cell symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09248
[Presentation] ピルビン酸投与とミトコンドリア移植による損傷軸索変性治療2024
- Author(s)
  大西諭一郎
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-22K09248
[Presentation] Prevention of caudal axonal degeneration in spinal cord injury by mitochondrial transfer2024
- Author(s)
  大西諭一郎
- Organizer
  Neuro2024
- Data Source
  KAKENHI-PROJECT-22K09248
[Presentation] 脊髄損傷部での過剰な細胞内ATPが神経障害性疼痛を引き起こす2022
- Author(s)
  大西諭一郎
- Organizer
  日本脊髄外科学会
- Data Source
  KAKENHI-PROJECT-22K09248
[Presentation] 脊髄損傷頭尾側でのエネルギー代謝と軸索変性の違い2021
- Author(s)
  大西諭一郎
- Organizer
  日本脊髄外科学会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 骨粗鬆性椎体骨折の治療2021
- Author(s)
  大西諭一郎
- Organizer
  日本脊髄外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 脊髄損傷急性期の病態理解に基づく治療法開発への取り組み2020
- Author(s)
  大西諭一郎、藤原翔、西麻哉、竹中朋文、中島伸彦、貴島晴彦
- Organizer
  日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 脊髄海綿状血管腫の保存的治療と外科治療2019
- Author(s)
  大西諭一郎
- Organizer
  第34回日本脊髄外科学会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 骨粗鬆性多発椎体骨折に対する治療経験2019
- Author(s)
  大西諭一郎
- Organizer
  近畿脊髄外科研究会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 頭蓋底陥入症に対する経口アプローチと経鼻アプローチによる到達範囲の検討2019
- Author(s)
  大西諭一郎
- Organizer
  第31回日本頭蓋底外科学会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] Management of spinal cord cavernous malformations2019
- Author(s)
  Yuichiro Onishi
- Organizer
  EuroSpine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 斜台部骨巨細胞腫に対して経鼻内視鏡下腫瘍摘出術を施行した1例2019
- Author(s)
  大西諭一郎
- Organizer
  第26回日本神経内視鏡学会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 斜台部骨巨細胞腫に対して経鼻内視鏡下腫瘍摘出術を施行した1例2019
- Author(s)
  大西諭一郎
- Organizer
  第一回関西経鼻内視鏡頭蓋底外科研究会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 髄内腫瘍摘出術における腫瘍周囲の術中血流評価2019
- Author(s)
  大西諭一郎
- Organizer
  第34回日本脊髄外科学会
- Data Source
  KAKENHI-PROJECT-19K09527
[Presentation] 嗅粘膜組織由来幹細胞のニューロンへの分化誘導の検討2018
- Author(s)
  大西諭一郎
- Organizer
  第17回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-16K10785
[Presentation] CBT法椎弓根スクリューによる腰椎分離部修復と椎体間固定術2016
- Author(s)
  大西諭一郎
- Organizer
  第31回日本脊髄外科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K10785
[Presentation] 腰椎開窓術後に腸腰筋膿瘍と化膿性脊椎炎を呈した１例2016
- Author(s)
  大西諭一郎
- Organizer
  Summer Forum for Practical Spinal Surgery
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16K10785
[Presentation] 内視鏡支援による片側進入-CBT法PLIF2016
- Author(s)
  大西諭一郎
- Organizer
  第6回低侵襲・内視鏡脊髄脊椎外科研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K10785
[Presentation] 嗅粘膜組織由来幹細胞のニューロンへの分化誘導の検討2016
- Author(s)
  大西諭一郎
- Organizer
  第17回日本分子脳神経外科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K10785
[Presentation] 頭蓋底嵌入症を伴うキアリⅠ型奇形に対する大孔部減圧および硬膜外層切除による治療成績2016
- Author(s)
  大西諭一郎
- Organizer
  第75回日本脳神経外科学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-16K10785
[Presentation] 嗅粘膜移植術後の脊髄損傷患者における脳機能解析2016
- Author(s)
  二宮貢士、岩月幸一、大西諭一郎、鷹羽良平、藤原　翔、吉峰俊樹
- Organizer
  第31回日本脊髄外科学会
- Place of Presentation
  東京
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-26861149
[Presentation] THE STEM CELL PROPETIES OF ADULT OLFACTORY HORIZONTAL BASAL CELLS2013
- Author(s)
  Yu-ichiro Ohnishi
- Organizer
  Glia meeting 2013
- Place of Presentation
  Berlin
- Data Source
  KAKENHI-PROJECT-25462215
[Presentation] オルファクトリースフィア細胞による中枢・末梢神経損傷治療の検討2013
- Author(s)
  大西諭一郎
- Organizer
  第14回日本分子脳神経外科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25462215
[Presentation] 慢性期脊髄損傷に対する自己嗅粘膜移植術2013
- Author(s)
  大西諭一郎
- Organizer
  第67回近畿脊髄外科研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25462215
[Presentation] オルファクトリースフィア細胞による中枢・末梢神経損傷治療の検討2013
- Author(s)
  大西諭一郎
- Organizer
  第28回日本脊髄外科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25462215
[Presentation] 当院での脊髄星細胞腫の治療2013
- Author(s)
  大西諭一郎
- Organizer
  第72回日本脳神経外科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25462215
[Presentation] 脊髄円錐部グリオーマの一例2013
- Author(s)
  大西諭一郎
- Organizer
  第66回日本脳神経外科学会近畿支部学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25462215
[Presentation] オルファクトリースフィア(OS)細胞のグリア細胞とニューロンへの分化の検討2013
- Author(s)
  大西諭一郎
- Organizer
  日本再生医療学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23791596
[Presentation] 慢性期脊髄損傷に対する嗅粘膜移植術2012
- Author(s)
  大西諭一郎
- Organizer
  日本再生医療学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2012-06-12
- Data Source
  KAKENHI-PROJECT-23791596
[Presentation] Conus medullaris近傍に発生したextramedullary ependymomaの１症例2012
- Author(s)
  森脇崇、岩月幸一、梅垣昌士，大西諭一郎、鷹羽良平、田村和義、吉峰俊樹
- Organizer
  第66回近畿脊髄外科研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659685

1. IWATSUKI Koichi (80346204)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. MORIWAKI takashi (20591019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. YOSHIMINE Toshiki (00201046)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. UMEGAKI Masao (30448063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. ISHIHARA Masahiro (00533803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. Kishima Haruhiko (10332743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 新沢康英 (70403186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鷹羽良平 (70774686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山本正道 (70423150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. HOSOMI Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. OSHINO Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 谷直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 森信彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 大川都史香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohnishi Yuichiro 大西 諭一郎

OHNISHI Yuichiro 大西 諭一郎

Research Projects

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経ニューロン変性に対する前角ニューロン選択的ミトコンドリア移植の分子機構の解明Principal Investigator

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Energy metabolism in neuronal degeneration at the caudal site of spinal cord injuryPrincipal Investigator

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Real-time monitoring of intracellular ATP concentration in acute spinal cord injuryPrincipal Investigator

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Application of human adult olfactory sphere cells as a cell source for treatment of spinal cord injuryPrincipal Investigator

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Evaluation of co-transplantation method between olfactory mucosa transplantation method and bone marrow mesenchymal cell medulla injection therapy

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Development of regenerative medicine by oligodendrocyte and schwann precursor cellsPrincipal Investigator

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Development of implantable three-dimensional device with the induction of olfactory ensheathing cells with high axonal regeneration effect

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Adult Olfactory Sphere Cells are aSource of Oligodendrocyte and Schwann Cell ProgenitorsPrincipal Investigator

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[Book] 脊椎脊髄ジャーナル2013

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[Book] 脊髄損傷慢性期に対する嗅粘膜移植法2011

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[Journal Article] Excess Intracellular ATP Causes Neuropathic Pain Following Spinal Cord Injury2024

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[Journal Article] Glycolytic System in Axons Supplement Decreased ATP Levels after Axotomy of the Peripheral Nerve.2023

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[Journal Article] White matter microstructural alterations in patients with neuropathic pain after spinal cord injury: a diffusion tensor imaging study2023

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[Journal Article] The SGLT2 inhibitor empagliflozin improves cardiac energy status via mitochondrial ATP production in diabetic mice.2023

Ohnishi Yuichiro 大西諭一郎

OHNISHI Yuichiro 大西諭一郎