Shiraishi Koji 白石晃司

… Alternative Names

Koji Shiraishi 白石晃司

SHIRAISHI Koji 白石晃司

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Researcher Number	00535255
Other IDs
Affiliation (Current)	2025: 山口大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 山口大学, 大学院医学系研究科, 教授 2019 – 2021: 山口大学, 大学院医学系研究科, 准教授 2017: 山口大学, 大学院医学系研究科, 准教授 2012 – 2016: 山口大学, 医学部附属病院, 講師
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 無精子症 / 精子形成 / トランスクリプトーム解析 / 精祖細胞 / 網羅的遺伝子解析 / テストステロン / トランスクリプトーム / プロミニンー１ / エストラジオール / 単一細胞トランスクリプトーム解析 … More / 非閉塞性無精子症 / 精巣 / 男性不妊 / ライディッヒ細胞 / アンドロゲンレセプター / 内分泌療法 … More Except Principal Investigator 薬剤感受性 / 免疫逃避 / 癌微小環境 / 一次繊毛 / 膀胱癌 / 人工精巣 / メカノホメオスターシス / YAP / 非閉塞性無精子症 Less

ヒト精巣のシングルセル空間的遺伝子解析による非閉塞性無精子症の病態解明Principal Investigator
- Principal Investigator
  
  白石晃司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
Generation of an artificial testis to overcome azoospermia
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Yamaguchi University
膀胱癌における一次繊毛の中心体制御メカニズム解明による新たな治療戦略の創出
- Principal Investigator
  
  松本洋明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
無精子症における精巣内内分泌環境に着目した単一細胞トランスクリプトーム解析Principal Investigator
- Principal Investigator
  
  白石晃司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
Single cell transcriptome analysis in men with non-obstructive azoospermiaPrincipal Investigator
- Principal Investigator
  
  Koji Shiraishi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
Genome-wide analysis for human spermatogenesisPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Koji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Yamaguchi University
Establishment of hormonal therapy for male infertilityPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Koji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Yamaguchi University

All 2023 2021 2020 2017 2016 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] HSF is required for gametogenesis2016
- Author(s)
  Koji Shiraishi
- Total Pages
  301
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K10642
[Journal Article] Prominin-1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice2023
- Author(s)
  Matsukuma H, Kobayashi Y, Oka S, Higashijima F, Kimura K, Yoshihara E, Sasai N, Shiraishi K.
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 22 Issue: 1
- DOI
  10.1002/rmb2.12514
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09475
[Journal Article] Genome medicine in male infertility: From karyotyping to single cell analysis2021
- Author(s)
  Koji Shiraishi
- Journal Title
  
  Journal of Obstetrics & Gynecology Research
  
  Volume: 47 Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09712
[Journal Article] Testicular Testosterone and Estradiol Concentrations and Aromatase Expression in Men with Nonobstructive Azoospermia.2021
- Author(s)
  Shiraishi K, Oka S, Matsuyama H.
- Journal Title
  
  Journal of Clinical Endocrinology & Metabolism
  
  Volume: 106 Issue: 4 Pages: 1803-1815
- DOI
  10.1210/clinem/dgaa860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09712
[Journal Article] Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders2017
- Author(s)
  Shiraishi K.、Shindo A.、Harada A.、Kurumizaka H.、Kimura H.、Ohkawa Y.、Matsuyama H.
- Journal Title
  
  Andrology
  
  Volume: 6 Issue: 1 Pages: 158-165
- DOI
  10.1111/andr.12438
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19356, KAKENHI-PUBLICLY-16H01219, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-15K10642
[Journal Article] Gonadotoropin actions on spermatogenesis and hormonal therapies for spermatogenic disorders [Review]2017
- Author(s)
  Koji Shiraishi, Hideyasu Matsuyama
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 2 Pages: 123-131
- DOI
  10.1507/endocrj.EJ17-0001
- NAID
  130005397055
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10642
[Journal Article] Effects of human chorionic gonadotoropin on testicular interstitial tissues in men with non-obstructive azoospermia.2017
- Author(s)
  Oka S, Shiraishi K, Matsuyama H.
- Journal Title
  
  Andrology
  
  Volume: 5 Issue: 2 Pages: 232-239
- DOI
  10.1111/andr.12292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10642
[Journal Article] Role of Heat Shock Factor 1 in Conserving Cholesterol Transportation in Leydig Cell Steroidogenesis via Steroidogenic Acute Regulatory Protein.2017
- Author(s)
  Oka S, Shiraishi K, Fujimoto M, Katiyar A, Takii R, Nakai A, Matsuyama H.
- Journal Title
  
  Endocrinology
  
  Volume: 158 Issue: 8 Pages: 2648-2658
- DOI
  10.1210/en.2017-00132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04706, KAKENHI-PROJECT-15K10642
[Journal Article] Predictive factors for sperm recovery after varicocelectomy in men with non-obsturctive azoospermia2017
- Author(s)
  Koji Shiraishi, Shintaro Oka, Hideyasu Matsuyama
- Journal Title
  
  Journal of Urology
  
  Volume: 197 Issue: 2 Pages: 485-490
- DOI
  10.1016/j.juro.2016.08.085
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10642
[Journal Article] Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis.2016
- Author(s)
  Urahama T, Harada A, Maehara K, Horikoshi N, Sato K, Sato Y, Shiraishi K, Sugino N, Osakabe A, Tachiwana H, Kagawa W, Kimura H, Ohkawa Y, Kurumizaka H.
- Journal Title
  
  Epigenetics Chromatin
  
  Volume: 9 Issue: 1 Pages: 1-16
- DOI
  10.1186/s13072-016-0051-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18457, KAKENHI-PLANNED-25116002, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PUBLICLY-26116521, KAKENHI-PROJECT-15J06922, KAKENHI-PROJECT-13J04024, KAKENHI-PROJECT-26830128, KAKENHI-PROJECT-26840025, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-15K10642
[Journal Article] Microdissection testicular sperm extraction and salvage hormonal treatment in patients with postchemotherapy azoospermia.2014
- Author(s)
  Shiraishi K, Matsuyama H
- Journal Title
  
  Urology
  
  Volume: 83 Issue: 1 Pages: 100-106
- DOI
  10.1016/j.urology.2013.08.043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592447
[Journal Article] Expression of testicular androgen receptor in non-obstructive azoospermia and its change after hormonal therapy2014
- Author(s)
  Kato Y, Shiraishi K, Matusyama H
- Journal Title
  
  Andrology
  
  Volume: 2 Issue: 5 Pages: 381-385
- DOI
  10.1111/j.2047-2927.2014.00240.x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592447
[Journal Article] Effect of hormonal therapy on spermatogonial DNA synthesis in men with non-obstructive azoospermia2013
- Author(s)
  Eriko Shinjo, Koji Shiraishi, Hideyasu Matsuyama
- Journal Title
  
  Andrology
  
  Volume: 1 Issue: 6 Pages: 929-935
- DOI
  10.1111/j.2047-2927.2013.00141.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592447
[Journal Article] TESE時代における内分泌療法の復権2012
- Author(s)
  白石晃司、松山豪泰
- Journal Title
  
  泌尿器科外科
  
  Volume: 25 Pages: 989-991
- Data Source
  KAKENHI-PROJECT-24592447
[Presentation] 非閉塞性無精子症に対する男性不妊治療の現状2023
- Author(s)
  白石晃司
- Organizer
  第41回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K09475
[Presentation] 内分泌疾患とgonadal function　内分泌・代謝疾患と造精機能2023
- Author(s)
  白石晃司
- Organizer
  第96回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09475
[Presentation] ヒト精祖細胞の単一細胞トランスクリプトーム解析と精巣内内分泌環境の関連2021
- Author(s)
  白石晃司、松隈　悠、田原正則、松山豪泰
- Organizer
  第９４回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09712
[Presentation] ヒト精祖細胞の単一細胞トランスクリプトーム解析と精巣内内分泌環境の関連2021
- Author(s)
  白石晃司
- Organizer
  日本アンドロロジー学会第４０回学術大会
- Data Source
  KAKENHI-PROJECT-19K09712
[Presentation] 非閉塞性無精子症における精巣内アロマターゼの発現2021
- Author(s)
  白石晃司
- Organizer
  日本アンドロロジー学会第39回学術大会
- Data Source
  KAKENHI-PROJECT-19K09712
[Presentation] 単一細胞トランスクリプトーム解析を用いたヒト精祖細胞の遺伝子発現プロファイリングによる造精機能障害のメカニズムの解明2020
- Author(s)
  白石晃司
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K09712
[Presentation] グローバリゼーションシンポジウム　日本アンドロロジー学会合同シンポジウムトランスクリプトーム解析による造精機能障害の解明2020
- Author(s)
  白石晃司
- Organizer
  第38回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K09712
[Presentation] 非閉塞性無精子症における精巣内アロマターゼの発現2020
- Author(s)
  白石晃司
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09712
[Presentation] ヒト精巣組織を用いたトランスクリプトーム解析による造精機能障害の解析2017
- Author(s)
  白石晃司
- Organizer
  日本アンドロロジー学会第36回学術大会
- Data Source
  KAKENHI-PROJECT-15K10642
[Presentation] Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders2017
- Author(s)
  Koji Shiraishi
- Organizer
  American Urological Association 2017
- Data Source
  KAKENHI-PROJECT-15K10642
[Presentation] 非閉塞性無精子症診療の進歩と課題2016
- Author(s)
  白石晃司、松山豪泰
- Organizer
  第68回西日本泌尿器科学会総会
- Place of Presentation
  山口県下関市（海峡メッセ下関）
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K10642
[Presentation] 精索静脈瘤を伴う非閉塞性無精子症のトランスクリプトーム解析と静脈瘤術後の精子回収予測2016
- Author(s)
  白石晃司、岡　真太郎、松山豪泰
- Organizer
  第104回日本泌尿器科学会総会
- Place of Presentation
  宮城県仙台市（仙台国際センター）
- Year and Date
  2016-04-25
- Data Source
  KAKENHI-PROJECT-15K10642
[Presentation] 男性不妊症とヒト精巣組織を用いた網羅的遺伝子解析2016
- Author(s)
  白石晃司、岡　真太郎、日高幸浩、松山豪泰
- Organizer
  日本アンドロロジー学会第３５回学術大会
- Place of Presentation
  群馬県前橋市（前橋テルサ）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K10642
[Presentation] Transcriptome analysis of testicular tissues in men with non-obstructive azoospermia with varicocele and predictive factors of sperm recovery after varicocelectomy2016
- Author(s)
  白石晃司
- Organizer
  American Urological Association2016
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-05-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10642
[Presentation] Transcriptome analysis of testicular tissues in men with non-obstructive azoospermia with varicocele and predictive factors of sperm recovery after varicocelectomy2016
- Author(s)
  Koji Shiraishi, Shintaro Oka, Hideyasu Matsuyama
- Organizer
  American Urological Association 2016
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-05-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10642
[Presentation] 非閉塞性無精子症に対するsalvage内分泌療法による精巣内テストステロン、精粗細胞におけるDNA合成およびアポトーシスの関連2013
- Author(s)
  白石晃司
- Organizer
  日本アンドロロジー学会第32回学術大会
- Place of Presentation
  大阪（大阪国際会議場）
- Data Source
  KAKENHI-PROJECT-24592447
[Presentation] Human chorionic gonadotropin-based hormonal therapy in men after failed microdissection testicular sperm extraction.2013
- Author(s)
  Koji Shiraishi, Hideyasu Matsuyama
- Organizer
  10th International Congress of Andrology
- Place of Presentation
  Melbourne (Australia)
- Data Source
  KAKENHI-PROJECT-24592447
[Presentation] Male Reproductive Microsurgery: Sperm Extraction2013
- Author(s)
  Koji Shiraishi
- Organizer
  第３３回国際泌尿器科学会
- Place of Presentation
  バンクーバー（カナダ）
- Data Source
  KAKENHI-PROJECT-24592447
[Presentation] Human chorionic gonadotropin-based hormonal therapy in men after failed microdissection testicular sperm extraction2012
- Author(s)
  Koji Shiraishi, Hideyasu Matsuyama
- Organizer
  32nd Congress of the Societe Internationale d’Urologie
- Place of Presentation
  Fukuoka（福岡国際会議場）
- Data Source
  KAKENHI-PROJECT-24592447
[Presentation] 非閉塞性無精子症に対する内分泌療法～効く症例と効かない症例～2012
- Author(s)
  白石晃司、松山豪泰
- Organizer
  第57回日本生殖医学会学術講演会
- Place of Presentation
  長崎市(長崎ブリックホール）
- Data Source
  KAKENHI-PROJECT-24592447
[Presentation] The effect of hormonal therapy on intratesticular testosterone level, androgen receptor expression and spermatogonial DNA synthesis in men with non-obstructive azoospermia
- Author(s)
  白石晃司
- Organizer
  American Urological Association 2014
- Place of Presentation
  オーランド(米国）
- Year and Date
  2014-05-18 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-24592447
[Presentation] 非閉塞性無精子症における精巣内アンドロゲンレセプターの発現と内分泌療法による変化
- Author(s)
  白石晃司
- Organizer
  日本アンドロロジー学会第33回学術大会
- Place of Presentation
  軽井沢プリンスホテルウェスト(長野県、軽井沢町）
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24592447

1. OHKAWA Yasuyuki (80448430)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 原田哲仁 (60596823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 清木誠 (50226619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 浅岡洋一 (10436644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 徳永雅之 (10845043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 田尾嘉誉 (30425417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 松本洋明 (60610673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 小林圭太 (20914021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宮本達雄 (40452627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 平田寛 (40781307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松山豪泰 (70209667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 藤本充章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 瀧井良祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中井彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiraishi Koji 白石 晃司

Koji Shiraishi 白石 晃司

SHIRAISHI Koji 白石 晃司

Research Projects

Research Products

Co-Researchers

ヒト精巣のシングルセル空間的遺伝子解析による非閉塞性無精子症の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of an artificial testis to overcome azoospermia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

膀胱癌における一次繊毛の中心体制御メカニズム解明による新たな治療戦略の創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

無精子症における精巣内内分泌環境に着目した単一細胞トランスクリプトーム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Single cell transcriptome analysis in men with non-obstructive azoospermiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome-wide analysis for human spermatogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of hormonal therapy for male infertilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] HSF is required for gametogenesis2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Prominin-1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genome medicine in male infertility: From karyotyping to single cell analysis2021

Author(s)

Journal Title

Data Source

[Journal Article] Testicular Testosterone and Estradiol Concentrations and Aromatase Expression in Men with Nonobstructive Azoospermia.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gonadotoropin actions on spermatogenesis and hormonal therapies for spermatogenic disorders [Review]2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

Shiraishi Koji 白石晃司

Koji Shiraishi 白石晃司

SHIRAISHI Koji 白石晃司

[Presentation] 内分泌疾患とgonadal function　内分泌・代謝疾患と造精機能2023

[Presentation] グローバリゼーションシンポジウム　日本アンドロロジー学会合同シンポジウムトランスクリプトーム解析による造精機能障害の解明2020