Ashida Noboru 芦田昇

… Alternative Names

ASHIDA Noboru 芦田昇

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Researcher Number	00538978
Other IDs
Affiliation (Current)	2025: 立命館大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2024: 立命館大学, 薬学部, 教授 2018 – 2021: 京都大学, 医学研究科, 講師 2016 – 2017: 京都大学, 医学研究科, 特定講師 2015: 京都大学, 医学(系)研究科(研究院), 特定講師 2013 – 2015: 京都大学, 医学(系)研究科(研究院), 講師 2009 – 2010: Kyoto University, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Basic Section 50010:Tumor biology-related / Collagenous pathology/Allergology / General pharmacology Except Principal Investigator Cardiovascular medicine
Keywords	Principal Investigator 炎症 / NF-kappaB / 癌随伴線維芽細胞 / NFκB / 非心筋細胞 / 心筋炎 / 筋線維芽細胞 / 石灰化 / 老化 / NF-κB … More / 大動脈弁狭窄症 / 自己免疫 / 強皮症 / 線維化 / 循環器 … More Except Principal Investigator デバイス / ステント血栓症 / 病理 / バイオマーカー / 冠動脈疾患 / 動脈硬化 / NRDc / 大動脈弁狭窄 / 退行性血管病変 / マイクロRNA / Neoatherosclerosis / ステント / nardilysin / microRNA / 大動脈弁狭窄症 / neoatherosclerosis Less

Roles of NF-lkappaB signaling in Cancer-Associated FibroblastsPrincipal Investigator
- Principal Investigator
  
  芦田昇
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Ritsumeikan University
非心筋細胞における炎症シグナルをターゲットとした心筋炎新規治療法の開発Principal Investigator
- Principal Investigator
  
  芦田昇
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyoto University
Exploring the mechanism of aortic stenosis by analyzing the novel vascular calcification model mousePrincipal Investigator
- Principal Investigator
  
  Ashida Noboru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyoto University
Elucidation of the mechanisms of neoatherosclerosis and degenerative vascular disease and development of novel therapeutic strategy
- Principal Investigator
  
  Kimura Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyoto University
Exploring the inflammation-autoimmune-fibrosis interaction by using novel mouse model for fibrosis and sclerodermaPrincipal Investigator
- Principal Investigator
  
  Ashida Noboru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kyoto University
Exploring the kinase-independent role of IKKβPrincipal Investigator
- Principal Investigator
  
  ASHIDA Noboru
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto University

All 2018 2017 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Deletion of IκB-Kinase β in Smooth Muscle Cells Induces Vascular Calcification Through β-Catenin-Runt-Related Transcription Factor 2 Signaling.2018
- Author(s)
  Al-Huseini I, Ashida N, Kimura T.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 7 Issue: 1
- DOI
  10.1161/jaha.117.007405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05297
[Journal Article] AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions.2014
- Author(s)
  Tien, D.N., Kishihata, M., Yoshikawa, A., Hashimoto, A., Sabe, H., Nishi, E., Kamei, K., Arai, H., Kita, T., Kimura, T., Yokode, M. and Ashida, N.
- Journal Title
  
  Sci Rep.
  
  Volume: 4 Issue: 1 Pages: 5094-5094
- DOI
  10.1038/srep05094
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25461497, KAKENHI-PUBLICLY-26116715, KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-26460121, KAKENHI-PROJECT-26670139
[Journal Article] Aspirin augments the expression of Adenomatous Polyposis Coli protein by suppression of IKKβ2014
- Author(s)
  Noboru Ashida, Masako Kishihata, Dat Nguyen Tien, Kaeko Kamei, Takeshi Kimura, Masayuki Yokode
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 446 Issue: 2 Pages: 460-464
- DOI
  10.1016/j.bbrc.2014.02.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461497, KAKENHI-PROJECT-26460121
[Journal Article] 炎症性シグナルの多彩な役割にみる抗炎症治療の問題点2013
- Author(s)
  芦田　昇
- Journal Title
  
  医学のあゆみ
  
  Volume: 246 Pages: 261-261
- Data Source
  KAKENHI-PROJECT-25461497
[Journal Article] IKK β regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.2011
- Author(s)
  Noboru Ashida, Sucharita SenBanerjee, Shohta Kodama, Shi Yin Foo, Matthew Coggins, Joel A. Spencer, Parisa Zamiri, Dongxiao Shen, Ling Li, Tracey Sciuto, Ann Dvorak, Robert E. Gerszten, Charles P. Lin, Michael Karin, Anthony Rosenzweig.
- Journal Title
  
  Corresponding Authors : Anthony Rosenzweig and Noboru Ashida doi:10.1038/ncomms1317
  
  Pages: 2-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890115
[Patent] NON-HUMAN ANIMAL MODEL FOR FIBROSIS AND USE THEREOF2013
- Inventor(s)
  芦田昇、横出正之、Michael Karin
- Industrial Property Rights Holder
  京都大学、UCSD
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-31
- Overseas
- Data Source
  KAKENHI-PROJECT-25461497
[Patent] NON-HUMAN ANIMAL MODEL FOR FIBROSIS AND USE THEREOF (線維化非ヒト動物及びその用途)2013
- Inventor(s)
  芦田昇, Nguyen Tien Dat, 横出正之, Michael Karin
- Industrial Property Rights Holder
  京都大学, カリフォルニア大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-31
- Acquisition Date
  2017-02-14
- Description
  米国登録番号：9565840
- Overseas
- Data Source
  KAKENHI-PROJECT-25461497
[Patent] NON-HUMAN ANIMAL MODEL FOR FIBROSIS AND USE THEREOF2013
- Inventor(s)
  芦田昇、Nguyen Tien Dat、横出正之、Michael Karin
- Industrial Property Rights Holder
  京都大学、カリフォルニア大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-544591
- Filing Date
  2013-10-31
- Description
  【米国】14/439,885 【欧州】13851788.3
- Data Source
  KAKENHI-PROJECT-25461497
[Patent] 線維化非ヒト動物及びその用途2013
- Inventor(s)
  芦田昇、Nguyen Tien Dat、横出正之、Michael Karin
- Industrial Property Rights Holder
  京都大学、カリフォルニア大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-544591
- Filing Date
  2013-10-31
- Acquisition Date
  2017-10-13
- Description
  登録番号：6222665
- Data Source
  KAKENHI-PROJECT-25461497
[Patent] NON-HUMAN ANIMAL MODEL FOR FIBROSIS AND USE THEREOF(線維化非ヒト動物及びその用途)2013
- Inventor(s)
  芦田昇、Nguyen Tien Dat、横出正之、Michael Karin
- Industrial Property Rights Holder
  京都大学、カリフォルニア大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-31
- Acquisition Date
  2017-02-14
- Description
  米国登録番号：9565840
- Overseas
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] 新規モデルマウスを用いた線維化メカニズム解析-慢性炎症の正体を探る-2018
- Author(s)
  芦田昇
- Organizer
  東海医学会講演会
- Place of Presentation
  東海大学医学部神奈川県伊勢原
- Year and Date
  2018-02-16
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] 新規強皮症/線維化モデルマウスの解析が示す慢性炎症と線維化の新たな捉え方2017
- Author(s)
  芦田昇
- Organizer
  第49回日本結合組織学会学術大会
- Place of Presentation
  三重県総合文化センター
- Year and Date
  2017-06-16
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Diverse roles of IKKβ in fibrosis2015
- Author(s)
  芦田　昇
- Organizer
  第3回御茶ノ水動脈硬化フォーラム
- Place of Presentation
  東京
- Year and Date
  2015-02-28
- Invited
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] NF-κB Activation both in Embryonic Cardiomyocytes and Fibroblasts Induces Congenital Cardiac Defects2015
- Author(s)
  Nguyen Tien Dat, Masayuki Yokode, Takeshi Kimura, Noboru Ashida
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Kinase-independent function of IKKβ in fibrosis2015
- Author(s)
  Dat Nguyen Tien, Masako Kishihata, Takeshi Kimura, Noboru Ashida
- Organizer
  第47回日本結合組織学会学術大会
- Place of Presentation
  東京
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] 心筋緻密化障害における心臓線維芽細胞NFκBの関与2015
- Author(s)
  芦田昇
- Organizer
  日本心臓血管発生研究会
- Place of Presentation
  福島
- Year and Date
  2015-12-18
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] 線維化における炎症シグナルの二面的役割2015
- Author(s)
  芦田昇、Dat Nguyen Tien, 岸畑雅子、横出正之、木村剛
- Organizer
  第1回国際心血管薬物療法学会日本部会学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Diverse roles of IKKβ in fibrosis2015
- Author(s)
  Noboru Ashida
- Organizer
  第3回御茶ノ水動脈硬化フォーラム
- Place of Presentation
  京都
- Year and Date
  2015-02-28
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Fibrosis induced by deletion of IKKβ2014
- Author(s)
  Noboru Ashida, Masayuki Yokode, Takeshi Kimura
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-03-21
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Fibrosis Induced by Deletion of IKKβ2014
- Author(s)
  Noboru Ashida, Masayuki Yokode, Takeshi Kimura
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] 新規NFκB抑制メカニズムとしてのAMAP12014
- Author(s)
  芦田　昇、Nguyen Tien Dat、岸畑　雅子、吉川　歩、佐邊　壽孝、亀井　加恵子、荒井　秀典、北　徹、横出　正之、木村　剛
- Organizer
  第51回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] 線維化・強皮症におけるNFκB2014
- Author(s)
  芦田昇、ダット・グエン・ティエン、中溝聡、鬼頭昭彦、亀井加恵子、椛島健治、宮地良樹、宇谷厚志、荒井秀典、木村剛、横出正之
- Organizer
  第46回日本結合組織学会学術大会・第61回マトリックス研究会大会合同学術集会
- Place of Presentation
  ウインクあいち
- Invited
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Roles of IKKβ in fibrosis2014
- Author(s)
  Dat Nguyen-Tien, Masako Kishihata, Megumi Nishio, Kaeko Kamei, Kenji Kabashima, Yoshiki Miyachi, Masayuki Yokode, Takeshi Kimura, Noboru Ashida
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] The roles of NFχB in Fibrosis and Systemic Sclerosis2014
- Author(s)
  Dat Nguyen Tien, Satoshi Nakamizo, Akihiko Kitoh, Kaeko Kamei, Kenji Kabashima, Yoshiki Miyachi, Atsushi Utani, Hidenori Arai, Takeshi Kimura, Masayuki Yokode, Noboru Ashida
- Organizer
  第46回日本結合組織学会・第61回マトリックス研究会合同学術集会
- Place of Presentation
  名古屋
- Year and Date
  2014-06-05
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] AMAP1 as a negative-feedback regulator of NF-κB2013
- Author(s)
  Dat Nguyen Tien, Masako Kishihata, Hisataka Sabe, Kaeko Kamei, Hidenori Arai, Toru Kita, Takeshi Kimura, Masayuki Yokode, Noboru Ashida
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Gender difference in regulation of MMP9 by NFκB signaling-implication for mechanism of cardiac and aneurysm rapture2013
- Author(s)
  Noboru Ashida, Masako Kishihata, Nguyen Tien Dat, Megumi Nishio, Kaeko Kamei, Masayuki Yokode
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Exploring the role of IKKβ2010
- Author(s)
  芦田昇
- Organizer
  動脈硬化若手研究会
- Place of Presentation
  クラブ関東:東京都千代田区丸ノ内1-3-1-19F
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21890115
[Presentation] IKKβ regulates Akt activation in kinase-independent manner in endothelial cells2009
- Author(s)
  芦田昇
- Organizer
  第41回日本動脈硬化学会総会・学術集会
- Place of Presentation
  海峡メッセ下関
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-21890115
[Presentation] IKK β regulates Akt activation in kinase-independent manner in endothelial cells2009
- Author(s)
  Noboru Ashida, Sucharita SenBanerjee, Shohta Kodama, Joel A.Spencer, Parisa Zamiri, Ling Li, Robert E.Gerszten, Charles P.Lin, Michael Karin, Anthony Rosenzweig, Masayuki Yokode.
- Organizer
  第41回日本動脈硬化学会総会・学術集会
- Place of Presentation
  於下関メッセ
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-21890115
[Presentation] 新規NFκB抑制メカニズムとしてのAMAP1
- Author(s)
  芦田　昇
- Organizer
  第51回臨床分子医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-04-11 – 2014-04-13
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] AMAP1 as a negative-feedback regulator of nuclear factor-kappa B
- Author(s)
  芦田　昇
- Organizer
  9th Metabolic Syndrome, Type2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  京都
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] The roles of NFκB in Fibrosis and Systemic Sclerosis
- Author(s)
  芦田　昇
- Organizer
  第46回日本結合組織学会・第61回マトリックス研究会　合同学術集会
- Place of Presentation
  名古屋
- Year and Date
  2014-06-05 – 2014-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-25461497
[Presentation] Deletion of IKKβ in myofibroblasts induces fibrosis and autoantibodies
- Author(s)
  芦田　昇
- Organizer
  第5回Molecular Cardiovascylar Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-25461497

1. Kimura Takeshi (80359786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 尾野亘 (00359275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 齋藤成達 (20467484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 西英一郎 (30362528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 森本剛 (30378640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 今井逸雄 (10625677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 伯野大彦 (80286476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐邉寿孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ashida Noboru 芦田 昇

ASHIDA Noboru 芦田 昇

Research Projects

Research Products

Co-Researchers

Roles of NF-lkappaB signaling in Cancer-Associated FibroblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非心筋細胞における炎症シグナルをターゲットとした心筋炎新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring the mechanism of aortic stenosis by analyzing the novel vascular calcification model mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanisms of neoatherosclerosis and degenerative vascular disease and development of novel therapeutic strategy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploring the inflammation-autoimmune-fibrosis interaction by using novel mouse model for fibrosis and sclerodermaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploring the kinase-independent role of IKKβPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Deletion of IκB-Kinase β in Smooth Muscle Cells Induces Vascular Calcification Through β-Catenin-Runt-Related Transcription Factor 2 Signaling.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aspirin augments the expression of Adenomatous Polyposis Coli protein by suppression of IKKβ2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 炎症性シグナルの多彩な役割にみる抗炎症治療の問題点2013

Author(s)

Journal Title

Data Source

[Journal Article] IKK β regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.2011

Author(s)

Journal Title

Data Source

[Patent] NON-HUMAN ANIMAL MODEL FOR FIBROSIS AND USE THEREOF2013

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] NON-HUMAN ANIMAL MODEL FOR FIBROSIS AND USE THEREOF (線維化非ヒト動物及びその用途)2013

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Acquisition Date

Description

Data Source

[Patent] NON-HUMAN ANIMAL MODEL FOR FIBROSIS AND USE THEREOF2013

Inventor(s)

Ashida Noboru 芦田昇

ASHIDA Noboru 芦田昇