Kawaai Katsuhiro 河合克宏

… Alternative Names

KAWAAI Katsuhiro 河合克宏

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Researcher Number	00553653
Other IDs	https://orcid.org/0000-0002-7502-0722
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 助教
Affiliation (based on the past Project Information) *help	2018 – 2024: 慶應義塾大学, 医学部(信濃町), 助教 2016 – 2017: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 2013 – 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員 2011 – 2012: 独立行政法人理化学研究所, 発生神経生物研究チーム, 研究員 2010: 独立行政法人理化学研究所, 発生神経生物研究チーム, 客員研究員
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Basic Section 56010:Neurosurgery-related / Basic Section 90120:Biomaterials-related / Neurochemistry/Neuropharmacology Except Principal Investigator Basic Section 56020:Orthopedics-related / General pharmacology
Keywords	Principal Investigator IRBIT / pH / リン酸化 / カルシウム / CaMKII / コルドーマ / マイクロＣＴ / 骨破壊 / RANKL / 破骨細胞 … More / JHC7細胞 / 脊索腫 / バイオミメティクス / ライブセルイメージング / 骨形成 / マイクロパターニング / 細胞動態解析 / インプラント / 石灰化 / 骨芽細胞 / 神経科学 / splicing varinats / 神経可塑性 / 多機能性蛋白質 / Splicing variants / 塩素イオン / LongIRBIT / TH / 行動異常 / DIA / NBC1 / モノアミン / 多動障害 / タンパク質相互作用 / CaMKIIα / knockout mice / brain … More Except Principal Investigator メカニカルストレス / 筋骨格 / 皮質骨内管腔 / 坐骨神経切除 / Ｘ線CTイメージング / 頭蓋骨 / 皮質骨 / 骨細胞 / 左右対称性 / Ｘ線顕微鏡 / 左右相称 / 左右対称 / トランスペアリング / 細胞キラリティ / 破骨細胞 / 骨芽細胞 / 骨格 / グリア細胞 / 細胞内pH / 細胞内Ca2+シグナル / トリパータイトシナプス / 神経可塑性 / 神経伝達 / 多重リン酸化 / NBCe1 / IP3R / multiple phosphorylation / IRBIT Less

Elucidation of the mechanisms for bone destruction in chordoma.Principal Investigator
- Principal Investigator
  
  河合克宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Keio University
Understanding the cellular basis of left-right symmetry in the skeleton
- Principal Investigator
  
  松尾光一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Keio University
Applicational study of bone formation mechanism based on calcified cartilagePrincipal Investigator
- Principal Investigator
  
  KAWAAI Katsuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Keio University
Regulation of intracellular pH and chloride changes by IRBIT family in neurons.Principal Investigator
- Principal Investigator
  
  Kawaai Katsuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Keio University
  Institute of Physical and Chemical Research
Clarifying the role of IRBIT in the coupling regulation of intracellular pH and Ca2+ in astrocytes.
- Principal Investigator
  
  MIZUTANI Akihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Showa Pharmaceutical University
Analysis of the pathogenic mechanism for neuropsychiatric disease-like abnormal behavior in IRBIT knockout mousePrincipal Investigator
- Principal Investigator
  
  KAWAAI Katsuhiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Institute of Physical and Chemical Research
Regulation of CaMKIIa by IP3R-pseudoligand IRBITPrincipal Investigator
- Principal Investigator
  
  KAWAAI Katsuhiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2011 2010

All Journal Article Presentation

[Journal Article] Both IRBIT and long-IRBIT bind to and coordinately regulate Cl -/HCO 3- exchanger AE2 activity through modulating the lysosomal degradation of AE22021
- Author(s)
  Itoh, R. Hatano, N. Murakami, M. Mitsumori, K. Kawasaki, S. Wakagi, T. Kanzaki, Y. Kojima, H. Kawaai, K. Mikoshiba, K. Hamada, K. Mizutani, A.
- Journal Title
  
  Sci Rep .
  
  Volume: 16 Issue: 1 Pages: 5990-5990
- DOI
  10.1038/s41598-021-85499-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11776, KAKENHI-PROJECT-19K12807, KAKENHI-PROJECT-20K06864, KAKENHI-PROJECT-18K02255, KAKENHI-PROJECT-21K15234
[Journal Article] Hypermineralization of hearing‐related bones by a specific osteoblast subtype2021
- Author(s)
  Yukiko Kuroda, Katsuhiro Kawaai, Naoya Hatano, Yanlin Wu, Hidekazu Takano, Atsushi Momose, Takuya Ishimoto, Takayoshi Nakano, Paul Roschger, Stephane Blouin, Koichi Matsuo
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: - Issue: 8 Pages: 1535-1547
- DOI
  10.1002/jbmr.4320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07256, KAKENHI-PROJECT-17H04015, KAKENHI-PROJECT-19K12807
[Journal Article] Transient appearance of Ca(2+) -permeable AMPA receptors is crucial for the production of repetitive LTP-induced synaptic enhancement (RISE) in cultured hippocampal slices.2020
- Author(s)
  Tominaga-Yoshino K, Urakubo T, Ueno Y, Kawaai K, Saito S, Tashiro T, Ogura A.
- Journal Title
  
  Hippocampus.
  
  Volume: - Issue: 7 Pages: 763-769
- DOI
  10.1002/hipo.23206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12807, KAKENHI-PROJECT-17K01986, KAKENHI-PROJECT-20K20864
[Journal Article] Trans-pairing between osteoclasts and osteoblasts shapes the cranial base during development.2019
- Author(s)
  Edamoto M, Kuroda Y, Yoda M, Kawaai K, Matsuo K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 297-297
- DOI
  10.1038/s41598-018-38471-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04015, KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-16K08506, KAKENHI-PROJECT-17K08548
[Journal Article] Bone2019
- Author(s)
  Matsuo K, Ji S, Miya A, Yoda M, Hamada Y, Tanaka T, Takao-Kawabata R, Kawaai K, Kuroda Y, Shibata S.
- Journal Title
  
  Innervation of the tibial epiphysis through the intercondylar foramen.
  
  Volume: 120 Pages: 297-304
- DOI
  10.1016/j.bone.2018.11.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04015, KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-16K08506, KAKENHI-PROJECT-17K08548
[Journal Article] Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.2017
- Author(s)
  Kawaai K, Ando H, Satoh N, Yamada H, Ogawa N, Hirose M, Mizutani A, Bonneau B, Seki G, Mikoshiba K.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 114(15) Issue: 15 Pages: 3921-3926
- DOI
  10.1073/pnas.1618514114
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-16K07068, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-17H00588
[Journal Article] Remodeling of Ca2+ signaling in cancer: Regulation of inositol 1,4,5-trisphosphate receptors through oncogenes and tumor suppressors.2017
- Author(s)
  Ando H, Kawaai K, Bonneau B, Mikoshiba K.
- Journal Title
  
  Adv Biol Regul.
  
  Volume: pii: S2212-4926(17) Pages: 30188-4
- DOI
  10.1016/j.jbior.2017.12.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-18K06540
[Journal Article] IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact2016
- Author(s)
  Bonneau B, Ando H, Kawaai K, Hirose M, Takahashi-Iwanaga H, Mikoshiba K.
- Journal Title
  
  Elife
  
  Volume: e19896 Pages: 1-27
- DOI
  10.7554/elife.19896
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-16K07075
[Journal Article] IRBIT is novel determinant of catecholamine homeostasis through the TH phosphorylation by CaMKIIα2015
- Author(s)
  Katsuhiro Kawaai, Akihiro Mizutani, Hirotaka Shoji, Naoko Ogawa, Etsuko Ebisui, Yukiko Kuroda, Shigeharu Wakana, Tsuyoshi Miyakawa, Chihiro Hisatsune, Katsuhiko Mikoshiba
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 未定 Issue: 17 Pages: 5515-5520
- DOI
  10.1073/pnas.1503310112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500451, KAKENHI-PROJECT-24590332, KAKENHI-PROJECT-15K06761, KAKENHI-PUBLICLY-15H01297, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-25242078
[Journal Article] IRBIT: A regulator of ion channels and ion transporters2014
- Author(s)
  Ando H, Kawaai K, Mikoshiba K
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 印刷中 Issue: 10 Pages: 2195-204
- DOI
  10.1016/j.bbamcr.2014.01.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458, KAKENHI-PROJECT-24700389, KAKENHI-PROJECT-25221002
[Journal Article] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice.2013
- Author(s)
  Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S.
- Journal Title
  
  Gastroenterology
  
  Volume: 13 Pages: 461-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700389
[Journal Article] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice.2013
- Author(s)
  Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S
- Journal Title
  
  Gastroenterology
  
  Volume: S0016-5085(13) Issue: 1 Pages: 232-241
- DOI
  10.1053/j.gastro.2013.03.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458, KAKENHI-PROJECT-24590332, KAKENHI-PROJECT-24591225, KAKENHI-PROJECT-24700389, KAKENHI-PROJECT-25221002
[Journal Article] Isolation of inositol 1, 4, 5-trisphosphate receptor-associating proteins and selective knockdown using RNA interference2010
- Author(s)
  Akihiro Mizutani, Kastuhiro Kawaai, Chihiro Hisatsune, Hideaki Ando, Takayuki Michikawa, and Katsuhiko Mikoshiba
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 645 Pages: 133-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700402
[Journal Article] Isolation of inositol 1,4,5-trisphosphate receptor-associating proteins and selective knockdown using RNA interference.2010
- Author(s)
  Mizutani A, Kawaai K, Hisatsune C, Ando H, Michikawa T, Mikoshiba K.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 645 Pages: 133-41
- Data Source
  KAKENHI-PROJECT-22700402
[Journal Article] Analysis of gene expression changes associated with long-lasting synaptic enhancement in hippocampal slice cultures after repetitive exposures to glutamate2010
- Author(s)
  Katsuhiro Kawaai, Keiko Tominaga-Yoshino, Tomoyoshi Urakubo, Naoko Taniguchi-Ishigaki, Yasumitsu Kondoh, Hideo Tashiro, Akihiko Ogura, Tomoko Tashiro
- Journal Title
  
  J Neurosci Res
  
  Volume: 88(13) Pages: 2911-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700402
[Journal Article] Analysis of gene expression changes associated with long-lasting synaptic enhancement in hippocampal slice cultures after repetitive exposures to glutamate.2010
- Author(s)
  Kawaai K, Tominaga-Yoshino K, Urakubo T, Taniguchi N, Kondoh Y, Tashiro H, Ogura A, Tashiro T.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 88(13) Pages: 2911-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700402
[Presentation] 骨芽細胞キラリティを反映する頭蓋冠と腓骨の微細形態2023
- Author(s)
  松尾光一, 宇佐美心手, 田口育武, 宮本諭, 黒田有希子, 野路しのぶ, 百生敦, 吉田光輝, 尾上弘晃, 河合克宏
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09217
[Presentation] 骨芽細胞キラリティを反映する頭蓋冠と腓骨の微細形態2023
- Author(s)
  松尾光一，宇佐美心手，田口育武，宮本諭，黒田有希子，野路しのぶ，百生敦，吉田光輝，尾上弘晃，河合克宏
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21467
[Presentation] 石灰化軟骨バイオミメティクによる骨形成促進表面の開発2023
- Author(s)
  河合克宏，黒田有希子，松尾光一
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21467
[Presentation] 皮質骨を挟んで向かい合った骨芽細胞と破骨細胞の「トランスペアリング」により長管骨は周囲の臓器形態に適合する2023
- Author(s)
  黒田有希子，河合克宏，依田昌樹，舘沼元春，百生敦，松尾光一
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21467
[Presentation] 石灰化軟骨バイオミメティクによる骨形成促進表面の開発2023
- Author(s)
  河合克宏, 黒田有希子, 松尾光一
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09217
[Presentation] 皮質骨を挟んで向かい合った骨芽細胞と破骨細胞の「トランスペアリング」により長管骨は周囲の臓器形態に適合する2023
- Author(s)
  黒田有希子, 河合克宏, 依田昌樹, 舘沼元春, 百生敦, 松尾光一
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09217
[Presentation] ホモキラルな骨芽細胞が左右対称な骨格を形作る2022
- Author(s)
  松尾光一、宇佐美心手、田口育武、宮本　諭、河合克宏、黒田有希子、吉田　光輝、尾上弘晃
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21467
[Presentation] ホモキラルな骨芽細胞が左右対称な骨格を形作る2022
- Author(s)
  松尾光一, 宇佐美心手, 田口育武, 宮本諭, 河合克宏, 黒田有希子
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09217
[Presentation] 筋肉の発達に応答した皮質骨形態変化は「内向きトランスペアリング」によって生み出される2022
- Author(s)
  黒田有希子, 河合克宏, 依田昌樹, 百生敦, 松尾光一
- Organizer
  第 42 回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-22K09217
[Presentation] 破骨細胞誘導因子による脊索腫細胞の破骨細胞様変化2022
- Author(s)
  河合克宏, 黒田有希子, 松尾光一
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09217
[Presentation] 筋肉の発達に応答した皮質骨形態変化は「内向きトランスペアリング」によって生み出される2022
- Author(s)
  黒田有希子、河合克宏、依田昌樹、百生敦、松尾光一
- Organizer
  第42回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-23K21467
[Presentation] 脊索腫における骨破壊機序の解明2021
- Author(s)
  河合克宏, 黒田有希子, 松尾光一
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K12807
[Presentation] 破骨細胞と骨芽細胞の内向きトランスペアリングで長管骨は周囲の形状変化に協調応答する2021
- Author(s)
  松尾光一、黒田有希子、河合克宏、依田昌樹、百生敦
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21467
[Presentation] Osteoclast-Osteoblast "Trans-pairing" across Cortical Bone Shapes Developing Long Bones2019
- Author(s)
  Koichi Matsuo, Masaki Yoda, Yukiko Kuroda, Katsuhiro Kawaai, Yanlin Wu, Hidekazu Takano, Atsushi Momose
- Organizer
  The American Society for Bone and Mineral Research 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12807
[Presentation] 内軟骨性骨化における軟骨原基と骨の関係－タルボＸ線位相トモグラフィー顕微鏡による形態解析－2019
- Author(s)
  松尾光一、姫シュウテイ、黒田有希子、河合克宏、呉彦霖、高野秀和、百生敦
- Organizer
  第19回東北大学多元物質科学研究所研究発表会
- Data Source
  KAKENHI-PROJECT-19K12807
[Presentation] 内軟骨性骨化で形成される耳小骨は軟骨原基より小さい2019
- Author(s)
  姫しゅうてい、黒田有希子、河合　克宏、百生　　敦、松尾　光一
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K12807
[Presentation] 超石灰化骨芽細胞によって形成された骨は II 型コラーゲンを含み骨密度が高くなる2019
- Author(s)
  黒田有希子、河合　克宏、松尾　光一
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K12807
[Presentation] Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family2017
- Author(s)
  Kawaai K, Ando H, Satoh N, Yamada H, Ogawa N, Hirose M, Mizutani A, Bonneau B, Seki G, Mikoshiba K.
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16K07075
[Presentation] Expression and distribution of GluR1 s ubunit of glutamate receptor during dev elopment of long-lasting synaptic enhan cement coupled with synaptogenesis2011
- Author(s)
  Tomoyoshi Urakubo, Katsuhiro Kawaai, Akihiko Ogura, Keiko Tominaga-Yoshino
- Organizer
  日本神経科学会
- Place of Presentation
  パシフィコ横浜神奈川県横浜市
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22700402
[Presentation] 繰り返しグルタミン酸刺激誘発性の長期神経可塑性に伴うアクチン骨格の再編成2011
- Author(s)
  河合克宏、冨永(吉野)恵子、浦久保知佳、谷口直子、近藤恭光、田代英夫、小倉明彦、田代朋子
- Organizer
  第54会日本神経化学会大会
- Place of Presentation
  瑠璃光石川県金沢市
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-22700402
[Presentation] 繰り返しグルタミン酸刺激誘発性の長期神経可塑性に伴うアクチン骨格の再編成2011
- Author(s)
  河合克宏、冨永(吉野)恵子、浦久保知佳、谷口直子、近藤恭光、田代英夫、小倉明彦、田代朋子
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光(石川県金沢市)
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-22700402
[Presentation] Expression and distribution of GluR1 subunit of glutamate receptor during development of long-lasting synaptic enhancement coupled with synaptogenesis2011
- Author(s)
  Tomoyoshi Urakubo, Katsuhiro Kawaai, Akihiko Ogura, Keiko Tominaga-Yoshino
- Organizer
  第34回日本神経科学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22700402

1. MIZUTANI Akihiro (30242861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SEKI Jouji (30206619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松尾光一 (40229422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 黒田有希子 (70455343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 神崎晶 (50286556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 安東英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 久恒智博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 御子柴克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 濱田浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawaai Katsuhiro 河合 克宏

KAWAAI Katsuhiro 河合 克宏

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Elucidation of the mechanisms for bone destruction in chordoma.Principal Investigator

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Understanding the cellular basis of left-right symmetry in the skeleton

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Applicational study of bone formation mechanism based on calcified cartilagePrincipal Investigator

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Regulation of intracellular pH and chloride changes by IRBIT family in neurons.Principal Investigator

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Clarifying the role of IRBIT in the coupling regulation of intracellular pH and Ca2+ in astrocytes.

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Analysis of the pathogenic mechanism for neuropsychiatric disease-like abnormal behavior in IRBIT knockout mousePrincipal Investigator

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Regulation of CaMKIIa by IP3R-pseudoligand IRBITPrincipal Investigator

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[Journal Article] Both IRBIT and long-IRBIT bind to and coordinately regulate Cl -/HCO 3- exchanger AE2 activity through modulating the lysosomal degradation of AE22021

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[Journal Article] Hypermineralization of hearing‐related bones by a specific osteoblast subtype2021

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[Journal Article] Transient appearance of Ca(2+) -permeable AMPA receptors is crucial for the production of repetitive LTP-induced synaptic enhancement (RISE) in cultured hippocampal slices.2020

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[Journal Article] Trans-pairing between osteoclasts and osteoblasts shapes the cranial base during development.2019

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[Journal Article] Bone2019

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[Journal Article] Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.2017

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[Journal Article] Remodeling of Ca2+ signaling in cancer: Regulation of inositol 1,4,5-trisphosphate receptors through oncogenes and tumor suppressors.2017

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Kawaai Katsuhiro 河合克宏

KAWAAI Katsuhiro 河合克宏

[Presentation] 皮質骨を挟んで向かい合った骨芽細胞と破骨細胞の「トランスペアリング」により長管骨は周囲の臓器形態に適合する2023