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Suzuki Hiroka  鈴木 裕可

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SUZUKI Hiroka  鈴木 裕可

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Researcher Number 00581026
Other IDs
Affiliation (Current) 2025: 愛知学院大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2018 – 2024: 愛知学院大学, 薬学部, 講師
2011 – 2016: 愛知学院大学, 薬学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related / Kidney internal medicine
Except Principal Investigator
General pharmacology / Basic Section 46030:Function of nervous system-related / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 50010:Tumor biology-related
Keywords
Principal Investigator
肝線維化 / Piezo1チャネル / casein kinase 2 / TRPA1 / 黄連含有イソキノリンアルカロイド / 糸球体腎炎
Except Principal Investigator
イオンチャネル / カチオンチャネル / 転写 / TRPチャネル … More / チャネル / 不活性化因子 / 活性化因子 / TRPC145 / 不安神経症 / Piezo1 / 機械刺激受容分子 / 滑膜線維芽細胞 / ion channel / mechanosensitive / cancer cells / PIEZO / がん / 分子構造 / 種差 / 伸展刺激 / Piezo / TRP / 細胞分化 / iPS因子 / iPS / ユビキチン / 細胞異常 / タンパク分解 / 炎症 / タンパク発現制御 Less
  • Research Projects

    (7 results)
  • Research Products

    (34 results)
  • Co-Researchers

    (6 People)
  •  Exploring endogenous activators of TRPC145 that induce anxiety disorders

    • Principal Investigator
      村木 克彦
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46030:Function of nervous system-related
    • Research Institution
      Aichi Gakuin University
  •  Mechanical stimulation exacerbates osteoarthritis (OA) by activating synovial fibroblasts.

    • Principal Investigator
      波多野 紀行
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Aichi Gakuin University
  •  Mechanosensitive PIEZO channel functions in cancer cells and their pathophysiological significance

    • Principal Investigator
      MURAKI KATSUHIKO
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Aichi Gakuin University
  •  Functional analysis of Piezo1, aimed to develop new therapeutic drug of liver fibrogenesis.Principal Investigator

    • Principal Investigator
      Suzuki Hiroka
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Aichi Gakuin University
  •  Transcriptional regulation of cation channels by iPS factors and the expression deficient diseases

    • Principal Investigator
      Muraki Katsuhiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Aichi Gakuin University
  •  Degradation of cation channel and the dysfunction

    • Principal Investigator
      MURAKI Katsuhiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Aichi Gakuin University
  •  Therapeutic effects of isoquinoline alkaloids isolated from Coptis Rhizoma, potential anti-glomerulonephritisPrincipal Investigator

    • Principal Investigator
      SUZUKI Hiroka
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Aichi Gakuin University

All 2022 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation

  • [Journal Article] Potent Activation of Human but Not Mouse TRPA1 by JT0102022

    • Author(s)
      M Matsubara, Y Muraki, N Hatano, H Suzuki & K Muraki
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 23 Issue: 22 Pages: 14297-14297

    • DOI

      10.3390/ijms232214297

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07599
  • [Journal Article] HIF-1α dependent upregulation of ZIP8, ZIP14, and TRPA1 modify intracellular Zn2+ accumulation in inflammatory synoviocytes.2021

    • Author(s)
      N Hatano, M Matsubara, H Suzuki, Y Muraki, K Muraki.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 22 Pages: 6349-6349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07599
  • [Journal Article] PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation.2019

    • Author(s)
      Maki Yoneda, Hiroka Suzuki, Noriyuki Hatano, Sayumi Nakano, Yukiko Muraki, Ken Miyazawa, Shigemi Goto, Katsuhiko Muraki.
    • Journal Title

      Int J Mol Sci

      Volume: 20(19) Issue: 19 Pages: 4960-4960

    • DOI

      10.3390/ijms20194960

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15828
  • [Journal Article] PIEZO1 Channel Is a Potential Regulator of Synovial Sarcoma Cell-Viability.2018

    • Author(s)
      Suzuki T, Muraki Y, Hatano N, Suzuki H, Muraki K.
    • Journal Title

      Int J Mol Sci.

      Volume: 19(5) Issue: 5 Pages: 1452-1452

    • DOI

      10.3390/ijms19051452

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15828
  • [Journal Article] Transcriptional repression of HER2 by ANO1 Cl- channel inhibition in human breast cancer cells with resistance to trastuzumab.2017

    • Author(s)
      M. Fujimoto, T. Inoue, H. Kito, S. Niwa, T. Suzuki, K. Muraki & S. Ohya
    • Journal Title

      Biochem. Biophys. Res. Comm.

      Volume: 482 Issue: 1 Pages: 188-194

    • DOI

      10.1016/j.bbrc.2016.11.033

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460349, KAKENHI-PROJECT-16K08285
  • [Journal Article] Molecular mechanisms underlying pimaric acid-induced modulation of voltage-gated K+ channels.2017

    • Author(s)
      Sakamoto K, Suzuki Y, Yamamura H, Ohya S, Muraki K, Imaizumi Y.
    • Journal Title

      J Pharmacol Sci.

      Volume: 印刷中 Issue: 4 Pages: 223-231

    • DOI

      10.1016/j.jphs.2017.02.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01408, KAKENHI-PROJECT-26460349, KAKENHI-PROJECT-16K08278, KAKENHI-PROJECT-26293021, KAKENHI-PUBLICLY-17H05537, KAKENHI-PROJECT-16H06215, KAKENHI-PROJECT-16K15127, KAKENHI-PROJECT-16K15128
  • [Journal Article] Diclofenac, a non-steroidal anti-inflammatory drug, is an antagonist of human TRPM3 isoforms.2016

    • Author(s)
      H Suzuki, E Sasaki, A Nakagawa, Y Muraki, N Hatano & K Murak
    • Journal Title

      Pharmacol Res & Persp

      Volume: 4(3) Issue: 3

    • DOI

      10.1002/prp2.232

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460349
  • [Journal Article] Downregulation of the Ca2+-activated K+ channel KCa3.1 by histone deacetylase inhibition in human breast cancer cells.2016

    • Author(s)
      Ohya, S Kanatsuka, N Hatano, H Kito, A Matsui, M Fujimoto, S Matsuba, S Niwa, P Zhan, T Suzuki & K Muraki.
    • Journal Title

      Pharmacol Res & Persp

      Volume: 4(2) Issue: 2

    • DOI

      10.1002/prp2.228

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460349, KAKENHI-PROJECT-25460111, KAKENHI-PROJECT-16K21474
  • [Journal Article] Oseltamivir blocks human neuronal nicotinic acetylcholine receptor-mediated currents.2015

    • Author(s)
      Muraki K, Hatano N, Suzuki H, Muraki Y, Iwajima Y, Maeda Y, Ono H.
    • Journal Title

      Basic Clin Pharmacol Toxicol.

      Volume: 116 Issue: 2 Pages: 87-95

    • DOI

      10.1111/bcpt.12290

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460349
  • [Journal Article] Downregulation of Ca2+-activated Cl- channel TMEM16A by the inhibition of histone deacetylase in TMEM16A-expressing cancer cells2015

    • Author(s)
      Matsuba S, Miwa S, Muraki K, Kanatsuka S, Nakazuno Y, Hatano N, Fujii M, Zhan P, Suzuki T, Ohya S
    • Journal Title

      Journal of Pharmacology & Experimental Therapeutics

      Volume: 351 Issue: 3 Pages: 510-518

    • DOI

      10.1124/jpet.114.217315

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460111, KAKENHI-PROJECT-26460349
  • [Journal Article] The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor.2014

    • Author(s)
      Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Yuka Itoh, Satoko Kimura, Hidetoshi Hayashi, Kikuo Onozaki, Yoshiaki Ohi, Akira Haji, Katsuhiko Muraki
    • Journal Title

      American Journal of Physiology -Cell Physiology

      Volume: 307 Issue: 4 Pages: C384-C394

    • DOI

      10.1152/ajpcell.00182.2013

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590085, KAKENHI-PROJECT-26460349, KAKENHI-PROJECT-26860042, KAKENHI-PROJECT-26870677
  • [Journal Article] TRPV4 partially participates in proliferation of human brain capillary endothelial cells.2013

    • Author(s)
      Noriyuki Hatano, Hiroka Suzuki, Yuka Itoh, Katsuhiko Muraki.
    • Journal Title

      Life Sciences

      Volume: Vol.92、No.4-5 Issue: 4-5 Pages: 317-324

    • DOI

      10.1016/j.lfs.2013.01.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790966, KAKENHI-PROJECT-24790267
  • [Journal Article] Stimulation of human TRPA1 channels by clinical concentrations of the anti-rheumatic drug, auranofin2013

    • Author(s)
      N Hatano, H Suzuki, Y Muraki & K Muraki
    • Journal Title

      Am. J. Physiol.,.Cell-Physiol.

      Volume: 304

    • Data Source
      KAKENHI-PROJECT-23590312
  • [Journal Article] Stimulation of human TRPA1 channels by clinical concentrations of theanti-rheumatic drug, auranofin.2013

    • Author(s)
      Noriyuki Hatano, Hiroka Suzuki, YukikoMuraki, Katsuhiko Muraki.
    • Journal Title

      American Journal of Physiology - Cell Physiology

      Volume: Vol.304、No.2 Pages: 354-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790966
  • [Journal Article] TRPV4 partially participates in proliferation of human brain capillary endothelial cells2013

    • Author(s)
      N. Hatano, H Suzuki, Y. Itoh & K. Muraki
    • Journal Title

      Life Sci.

      Volume: 92 Pages: 317-324

    • Data Source
      KAKENHI-PROJECT-23590312
  • [Journal Article] Differential gene expression in rat vascular smooth muscle cells following treatment with coptisine exerts aselective antiproliferative effect.2012

    • Author(s)
      Hiroka Suzuki, Horoki Tanabe, HajimeMizukami, Makoto Inoue.
    • Journal Title

      Journal of Natural Products

      Volume: Vol.74、No.4 Issue: 4 Pages: 634-638

    • DOI

      10.1021/np100645d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790966
  • [Journal Article] HIF1αswitches on TRPA1 gene expression via a hypoxia response element-like motif to modulate cytokine release2012

    • Author(s)
      N Hatano, Y Itoh, H Suzuki, Y Muraki, H Hayashi, K Onozaki, IC Wood, DJ Beech & K Muraki
    • Journal Title

      J. Biol. Chem.

      Volume: 287 Pages: 31962-31972

    • Data Source
      KAKENHI-PROJECT-23590312
  • [Journal Article] HIF1α switches on TRPA1 gene expression via a hypoxia response element-like motif to modulate cytokine release2012

    • Author(s)
      N Hatano, Y Itoh, H Suzuki, Y Muraki, H Hayashi, K Onozaki, IC Wood, DJ Beech & K Muraki
    • Journal Title

      J. Biol. Chem.

      Volume: 287 Issue: 38 Pages: 31962-31972

    • DOI

      10.1074/jbc.m112.361139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590312, KAKENHI-PROJECT-23790966, KAKENHI-PROJECT-24590085, KAKENHI-PROJECT-24790267
  • [Journal Article] Differential gene expression in rat vascular smooth muscle cells following treatment with coptisine exerts a selective antiproliferative effect.2011

    • Author(s)
      Suzuki H, Tanabe H, Mizukami H, Inoue M.
    • Journal Title

      J Nat Prod.

      Volume: 74(4) Pages: 634-638

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790966
  • [Presentation] 滑膜線維芽様細胞におけるTRPA1発現誘導を介したサイトカイン分泌制御機構2013

    • Author(s)
      波多野紀行, 伊藤友香, 鈴木裕可, 村木由起子, 林秀敏, 小野嵜菊夫, Wood Ian,Beech David, 村木克彦
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜(29amp-118)
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] Inflammatory stimulation induces expression of TRPA1 channel to regulate cytokine release2013

    • Author(s)
      Noriyuki Hatano, Yuka Itoh, Hiroka Suzuki, Yukiko Muraki, Hidetoshi Hayashi, Kikuo Onozaki, Ian Wood, David Beech, Katsuhiko Muraki
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡(P1-99)
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] 炎症性刺激により誘導されるTRPA1は細胞内亜鉛濃度を制御する2013

    • Author(s)
      波多野紀行, 鈴木裕可, 村木由起子, 伊藤友香, 林秀敏, 小野嵜菊夫, Wood Ian,Beech David, 村木克彦
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜(29amp-117)
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] 低酸素誘導因子HIF1αによるTRPA1チャネル発現制御機構2013

    • Author(s)
      波多野紀行, 伊藤友香, 鈴木裕可, 村木由起子, 林秀敏, 小野嵜菊夫, Wood Ian,Beech David, 村木克彦
    • Organizer
      平成25年度日本薬学会東海支部総会・大会
    • Place of Presentation
      名古屋(H1510)
    • Year and Date
      2013-07-06
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] Potent activation of TRPA1 channel byNADPH oxidase inhibitors2013

    • Author(s)
      Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Yuka Itoh, Hidetoshi Hayashi, Kikuo Onozaki, Katsuhiko Muraki.
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-23790966
  • [Presentation] ヒト脳毛細血管内皮細胞においてhistamineにより惹起されるCl-電流におけるanoctaminチャネルの寄与の検討2013

    • Author(s)
      波多野紀行, 鈴木裕可, 村木由起子, 大矢進, 村木克彦
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      名古屋(B-5)
    • Year and Date
      2013-07-12
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] TRPA1 channel is a key regulator of intracellular Zn^<2+> in inflammatory synoviocytes2013

    • Author(s)
      Noriyuki Hatano, Hiroka Suzuki, Yuka Itoh, Yukiko Muraki, Hidetoshi Hayashi, Kikuo Onozaki, Katsuhiko Muraki
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡(P2-98)
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] NADPHオキシダーゼ阻害剤はTRPA1チャネルを活性化する2013

    • Author(s)
      鈴木裕可, 波多野紀行, 村木由起子, 伊藤友香, 林秀敏, 小野嵜菊夫, 村木克彦
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜(29amp-123)
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] Transcriptional regulation of transient receptor potential ankyrin 1 channel gene expression by hypoxia inducible factor-1α2013

    • Author(s)
      Noriyuki Hatano, Yuka Itoh, Hiroka Suzuki, Yukiko Muraki, Hidetoshi Hayashi, Kikuo Onozaki, Ian Wood, David Beech, Katsuhiko Muraki
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡(P3-89)
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] Potent activation of TRPA1 channel by NADPH oxidase inhibitors2013

    • Author(s)
      Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Yuka Itoh, Hidetoshi Hayashi, Kikuo Onozaki, Katsuhiko Muraki
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡(P1-151)
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] NADPHオキシダーゼ阻害剤はTRPA1チャネルを活性化する2013

    • Author(s)
      鈴木裕可,波多野紀行,村木由起子,伊藤友香,林秀敏,小野嵜菊夫,村木克彦
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-23790966
  • [Presentation] Potent activation of TRPA1 channel by NADPH oxidase inhibitors.2013

    • Author(s)
      Hiroka Suzuki
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790966
  • [Presentation] 抗リウマチ薬オーラノフィンはTRPA1チャネルを活性化する2012

    • Author(s)
      鈴木裕可,楠神枝里香,神谷絵梨奈,藤嵩久,波多野紀行,村木由起子,村木克彦
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-23790966
  • [Presentation] Selective and potent activation of human TRPA1 by a disease modifying anti-rheumatic drug, auranofin2012

    • Author(s)
      Noriyuki Hatano, Erika Kusugami, Erina Kamiya, Hiroka Suzuki, Yukiko Muraki, Katsuhiko Muraki
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都(P2-19-3)
    • Year and Date
      2012-03-15
    • Data Source
      KAKENHI-PROJECT-23590312
  • [Presentation] Selective and potent activation of human TRPA1 by a disease modifying anti-rheumatic drug, auranofin2012

    • Author(s)
      Noriyuki Hatano, Erika Kusugami, Erina Kamiya, Hiroka Suzuki, Yukiko Muraki, Katsuhiko Muraki.
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-23790966
  • 1.  HATANO Noriyuki (50454319)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 19 results
  • 2.  MURAKI Katsuhiko (20254310)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 20 results
  • 3.  FUJII Masanori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  林 秀敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  大矢 進
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  今泉 祐治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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