HIYOSHI Hirotaka 日吉大貴

… Alternative Names

Hiyoshi Hirotaka 日吉大貴

日吉大貴ヒヨシヒロタカ

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Researcher Number	00585599
Other IDs
Affiliation (Current)	2025: 長崎大学, 熱帯医学研究所, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 長崎大学, 熱帯医学研究所, 准教授 2013: 大阪大学, 微生物病研究所, その他
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology)
Keywords	Principal Investigator T3SS / サルモネラ / マウス全身感染モデル / エフェロサイトーシス / 好中球 / マクロファージ / シングルセルRNA-seq / Vi抗原 / パラチフスC菌 / チフス菌 … More / 腸チフス / 全身感染 / ３型分泌装置 / 侵襲感染 Less

新規scRNA-seq技術を用いたサルモネラ3型分泌装置による宿主免疫防御機構再構成の解析Principal Investigator
- Principal Investigator
  
  日吉大貴
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Nagasaki University
Analysis virulence factors of S. Typhi by using an alternative mouse infection modelPrincipal Investigator
- Principal Investigator
  
  日吉大貴
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Nagasaki University
Efferocytosis mediates Salmonella endurance during neutrophil-killing activities.Principal Investigator
- Principal Investigator
  
  Hiyoshi Hirotaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Nagasaki University
アクチン骨格再構成を誘導する新規T3SSエフェクターの解析Principal Investigator
- Principal Investigator
  
  日吉大貴
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Osaka University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis2022
- Author(s)
  Hiyoshi Hirotaka、English Bevin C.、Diaz-Ochoa Vladimir E.、Wangdi Tamding、Zhang Lillian F.、Sakaguchi Miako、Haneda Takeshi、Tsolis Ren?e M.、B?umler Andreas J.
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 30 Issue: 2 Pages: 163-170.e6
- DOI
  10.1016/j.chom.2021.12.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07543, KAKENHI-PROJECT-21K07027
[Journal Article] The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN2022
- Author(s)
  Zhang Lillian F.、Lepenies Bernd、Nakamae Sayuri、Young Briana M.、Santos Renato L.、Raffatellu Manuela、Cobb Brian A.、Hiyoshi Hirotaka、Baumler Andreas J.
- Journal Title
  
  mBio
  
  Volume: 13 Issue: 6
- DOI
  10.1128/mbio.02733-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07027
[Journal Article] Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes2022
- Author(s)
  Liou Megan J.、Miller Brittany M.、Litvak Yael、Nguyen Henry、Natwick Dean E.、Savage Hannah P.、Rixon Jordan A.、Mahan Scott P.、Hiyoshi Hirotaka、Rogers Andrew W.L.、Velazquez Eric M.、Butler Brian P.、Collins Sean R.、McSorley Stephen J.、Harshey Rasika M.、Byndloss Mariana X.、Simon Scott I.、Baumler Andreas J.
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 30 Issue: 6 Pages: 836-847.e6
- DOI
  10.1016/j.chom.2022.04.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] Analysis of alternative human typhoid mouse infection model2024
- Author(s)
  Hirotaka Hiyoshi
- Organizer
  21st Bay Area Microbial Pathogenesis Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] Analysis of alternative human typhoid mouse infection model2024
- Author(s)
  Hirotaka Hiyoshi
- Organizer
  21st Bay Area Microbial Pathogenesis Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0276
[Presentation] A mouse model of human typhoid fever2024
- Author(s)
  Hoan T Pham, Hirotaka Hiyoshi, Toshio Kodama
- Organizer
  第１回AMED SCARDA「ワクチン開発のための世界トップレベル研究開発拠点の形成事業」合同シンポジウム
- Data Source
  KAKENHI-PROJECT-22KK0276
[Presentation] A mouse model of human typhoid fever2024
- Author(s)
  Hoan Thi Pham, Hirotaka Hiyoshi, Toshio Kodama
- Organizer
  第１回AMED SCARDA「ワクチン開発のための世界トップレベル研究開発拠点の形成事業」合同シンポジウム
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] Functional analysis of Vi capsular polysaccharide on an alternative Salmonella enterica serovar Typhi infection model2023
- Author(s)
  Hoan T Pham, Hirotaka Hiyoshi, Toshio Kodama
- Organizer
  The 21st Awaji International Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0276
[Presentation] An alternative S. Typhi mouse infection model2023
- Author(s)
  Hirotaka Hiyoshi
- Organizer
  Gordon Research Conference Salmonella Biology and Pathogenesis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] Virulence factors perforate the pathogen-containing vacuole to generate a find-me signal for efferocytosis2023
- Author(s)
  Hirotaka Hiyoshi
- Organizer
  U.S. Panel on Cholera and Other Bacterial Enteric Infections
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] Vi capsular polysaccharide of Salmonella Typhi promotes macrophage phagocytosis by binding DC-SIGN2023
- Author(s)
  Lillian F. Zhang, Andreas J. Baumler, 日吉大貴
- Organizer
  第96回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] Functional analysis of Vi capsular polysaccharide on an alternative Salmonella enterica serovar Typhi infection model2023
- Author(s)
  Hoan Thi Pham, Hirotaka Hiyoshi, Toshio Kodama
- Organizer
  The 21st Awaji International Forum on Infection and Immunity
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] An alternative S. Typhi mouse infection model2023
- Author(s)
  Hirotaka Hiyoshi
- Organizer
  Gordon Research Conference Salmonella Biology and Pathogenesis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0276
[Presentation] The Vi capsular polysaccharide of Salmonella Typhi promotes macrophage phagocytosis by binding the human C-type lectin DC-SIGN2022
- Author(s)
  Lillian F. Zhang, Andreas J. Baumler, Hirotaka Hiyoshi
- Organizer
  The 20th Awaji International Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] チフス菌のVi抗原を介した侵襲感染性発揮機構の解析2022
- Author(s)
  Lillian Zhang, 中前早百合, 児玉年央, Andreas Baumler, 日吉大貴
- Organizer
  九州微生物研究フォーラム 2022
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] The Vi capsular polysaccharide of Salmonella Typhi promotes macrophage phagocytosis by binding the human C-type lectin DC-SIGN2022
- Author(s)
  Lillian F. Zhang, Andreas J. Baumler, Hirotaka Hiyoshi
- Organizer
  第51回　日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K07027
[Presentation] Virulence factors perforate the pathogen-containing vacuole to generate a find-me signal for efferocytosis2021
- Author(s)
  Hiyoshi Hirotaka, Tsolis M. Renee, Baumler J. Andreas
- Organizer
  The 19th Awaji International Forum on Infection and Immunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07027

1. 奥崎大介 (00346131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 羽田健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIYOSHI Hirotaka 日吉 大貴

Hiyoshi Hirotaka 日吉 大貴

日吉 大貴 ヒヨシ ヒロタカ

Research Projects

Research Products

Co-Researchers

新規scRNA-seq技術を用いたサルモネラ3型分泌装置による宿主免疫防御機構再構成の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis virulence factors of S. Typhi by using an alternative mouse infection modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Efferocytosis mediates Salmonella endurance during neutrophil-killing activities.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アクチン骨格再構成を誘導する新規T3SSエフェクターの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Analysis of alternative human typhoid mouse infection model2024

Author(s)

Organizer

Data Source

[Presentation] Analysis of alternative human typhoid mouse infection model2024

Author(s)

Organizer

Data Source

[Presentation] A mouse model of human typhoid fever2024

Author(s)

Organizer

Data Source

[Presentation] A mouse model of human typhoid fever2024

Author(s)

Organizer

Data Source

[Presentation] Functional analysis of Vi capsular polysaccharide on an alternative Salmonella enterica serovar Typhi infection model2023

Author(s)

Organizer

Data Source

[Presentation] An alternative S. Typhi mouse infection model2023

Author(s)

Organizer

Data Source

[Presentation] Virulence factors perforate the pathogen-containing vacuole to generate a find-me signal for efferocytosis2023

Author(s)

Organizer

Data Source

[Presentation] Vi capsular polysaccharide of Salmonella Typhi promotes macrophage phagocytosis by binding DC-SIGN2023

Author(s)

Organizer

Data Source

[Presentation] Functional analysis of Vi capsular polysaccharide on an alternative Salmonella enterica serovar Typhi infection model2023

Author(s)

Organizer

HIYOSHI Hirotaka 日吉大貴

Hiyoshi Hirotaka 日吉大貴

日吉大貴ヒヨシヒロタカ