HISADOME Kazunari 久留和成

Researcher Number	00592081
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2022: 北海道大学, 歯学研究院, 助教 2016: 北海道大学, 歯学研究科, 助教 2014 – 2015: 北海道大学, 歯学研究科(研究院), 助教 2011 – 2013: 佐賀大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Environmental physiology(including physical medicine and nutritional physiology) / General pharmacology / Metabolomics Except Principal Investigator Basic Section 57010:Oral biological science-related / Functional basic dentistry
Keywords	Principal Investigator 肥満 / 糖尿病 / 中枢神経 / 摂食調節 / 代謝学 / 内分泌 / 生理学 / 糖尿 / 神経生理 / GLP-1 / メタボリックシンドローム / 薬理学 … More Except Principal Investigator … More ラット / 迷走神経 / 最後野 / 嘔吐 / 悪心 / 化学受容器引き金帯 / 味覚反応試験 / 条件付け味覚嫌悪 / 孤束核 / 飲水行動 / 味覚嫌悪学習 / 催吐薬 / 摂食行動 / セロトニン受容体 / トラネキサム酸 / エメチン / 化学受容性 / 化学受容器 Less

Neurophysiological study of central mechanisms for nausea and vomiting to create a new antiemetic therapy.
- Principal Investigator
  
  FUNAHASHI MAKOTO
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Hokkaido University
Analysis of hunger and satiety signalling pathway from peripheral to central nervous system using visualizing technology of a marker of neuronal activationPrincipal Investigator
- Principal Investigator
  
  Hisadome Kazunari
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Hokkaido University
Study of neuronal activity, a molecular basis and a behavioral change related to chemoreceptor-mediated nausea and emesis.
- Principal Investigator
  
  FUNAHASHI MAKOTO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hokkaido University
Neuromodulatory effects of feeding signasl in GLP-1 releasing neurons of the brainstemPrincipal Investigator
- Principal Investigator
  
  Hisadome Kazunari
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hokkaido University
  Saga University
Molecular biological analysis of GLP-1 releasing neurons in the brainstemPrincipal Investigator
- Principal Investigator
  
  HISADOME Kazunari
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Saga University

All 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Effects of intraperitoneally administered L-histidine on food intake, taste, and visceral sensation in rats2016
- Author(s)
  Okusha Y, Hirai Y, Maezawa H, Hisadome K, Inoue N, Yamazaki Y, Funahashi M.
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: － Issue: 4 Pages: 467-474
- DOI
  10.1007/s12576-016-0476-x
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05880, KAKENHI-PROJECT-16K11471, KAKENHI-PROJECT-16K11621, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] Movement-related cortical magnetic fields associated with self-paced tongue protrusion in humans2016
- Author(s)
  Maezawa H, Oguma H, Hirai Y, Hisadome K, Shiraishi H, Funahashi M
- Journal Title
  
  Neuroscience Research
  
  Volume: 117 Pages: 22-27
- DOI
  10.1016/j.neures.2016.11.010
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05880, KAKENHI-PROJECT-16K11471, KAKENHI-PROJECT-16K11621, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs.2011
- Author(s)
  Hisadome Kazunari
- Journal Title
  
  Diabetes
  
  Volume: 60 (11) Pages: 2701-2709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791035
[Journal Article] Glucagon-like peptide 1 and the brain: central actions -central sources?2011
- Author(s)
  Trapp S, Hisadome K
- Journal Title
  
  Autonomic Neuroscience
  
  Volume: 161(1-2) Issue: 1-2 Pages: 14-19
- DOI
  10.1016/j.autneu.2010.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791035
[Journal Article] CCK stimulation of GLP-1 neurons involves a_1-adrenoceptor-mediated increase in glutamatergic synaptic inputs2011
- Author(s)
  Hisadome K, Reiman F, Gribble FM, Trapp S
- Journal Title
  
  Diabetes
  
  Volume: 60 (11) Issue: 11 Pages: 2701-2709
- DOI
  10.2337/db11-0489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] Behavioral study on nausea induction by serotonin agonists in rats.2020
- Author(s)
  実藤潤，平井喜幸，久留和成，藤田麻由，蘇韶懿，山崎七愛，舩橋誠
- Organizer
  第97回日本生理学会
- Data Source
  KAKENHI-PROJECT-19K10039
[Presentation] Effects of vagotomy and lesions of the area postrema on nausea induced by tranexamic acid.2019
- Author(s)
  Mayu Fujita, Yoshiyuki Hirai, Kazunari Hisadome，Makoto Funahashi
- Organizer
  北米神経科学学会（Society for Neuroscience）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10039
[Presentation] Effects of vagotomy and area postrema lesion on induction of emesis by emetine.2019
- Author(s)
  Makoto Funahashi, Yoshiyuki Hirai，Mayu Fujita，Kazunari Hisadome, HItoshi Maezawa
- Organizer
  FAOPS＆第96回日本生理学会合同大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11471
[Presentation] Analysis of nausea induced by emetine or cisplatin in rats.2019
- Author(s)
  Makoto Funahashi, Yoshiyuki Hirai, Kazunari Hisadome, Mayu Fujita, Shaoyi Su, Nanae Yamazaki, Jun Sanefuji
- Organizer
  北米神経科学学会（Society for Neuroscience）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10039
[Presentation] エメチン誘発の悪心に対する迷走神経切除と最後野損傷の影響2018
- Author(s)
  舩橋誠，平井喜幸，藤田麻由，久留和成，前澤仁志
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11471
[Presentation] トラネキサム酸の悪心・嘔吐誘発機序の解析2018
- Author(s)
  藤田麻由，久留和成，平井喜幸，前澤仁志，舩橋誠
- Organizer
  第98回北海道医学大会生理系分科会（日本生理学会北海道地方会）
- Data Source
  KAKENHI-PROJECT-16K11471
[Presentation] 絶食ラットの脳幹部における高血糖の影響2017
- Author(s)
  播磨美樹，久留和成，平井喜幸，北川善政，舩橋誠
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松市・アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K11471
[Presentation] エメチンの催吐作用とその中枢機序2017
- Author(s)
  佐藤孝紀, 久留和成, 平井喜幸, 舩橋誠
- Organizer
  歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-16K11471
[Presentation] The role of GLP-1 releasing neurons inappetite regulation : application possibility in obesity drug.2016
- Author(s)
  久留和成
- Organizer
  日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460336
[Presentation] 食欲調節ペプチドに対するマウス脳幹部GLP-1分泌神経細胞の応答特性2015
- Author(s)
  久留和成
- Organizer
  歯科基礎医学会
- Place of Presentation
  朱鷺メッセ
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25460336
[Presentation] マウス脳幹部におけるGLP-1分泌細胞の電気生理学的特性2015
- Author(s)
  久留和成
- Organizer
  日本生理学会　北海道地方会
- Place of Presentation
  旭川医科大学
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-25460336
[Presentation] Excitatory effects of CCK on GLP-1 releasing neurons are mediated via adrenergic neurons.2013
- Author(s)
  久留和成
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] GLP-1分泌神経細胞におけるグルコース受容ニューロンの解析2013
- Author(s)
  久留　和成
- Organizer
  第86回　日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] Neuromodulatory effects of feeding peptides in GLP-1 releasing neurons of mouse brainstem.2012
- Author(s)
  久留和成
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] GLP-1分泌神経細胞におけるアドレナリン作動性神経を介したCCK興奮作用2012
- Author(s)
  久留　和成
- Organizer
  第85回　日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] GLP-1 分泌神経細胞のグルコース応答に関する解析2012
- Author(s)
  久留和成
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] 脳幹GLP-1分泌細胞におけるアドレナリン受容体を介した興奮性シナプス入力の解析2011
- Author(s)
  久留和成
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] 脳幹GLP-1分泌細胞におけるアドレナリン受容体を介した興奮性シナプス入力の解析2011
- Author(s)
  久留　和成
- Organizer
  第64回　日本薬理学会西南部会
- Place of Presentation
  KKRホテル博多（福岡）
- Data Source
  KAKENHI-PROJECT-23791035
[Presentation] GLP-1分泌神経細胞の細胞外グルコース応答に関する解析
- Author(s)
  久留　和成
- Organizer
  第65回　日本薬理学会西南部会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23791035

1. FUNAHASHI MAKOTO (80221555)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 前澤仁志 (80567727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 平井喜幸 (40344519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 船橋誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

HISADOME Kazunari 久留 和成

Research Projects

Research Products

Co-Researchers

Neurophysiological study of central mechanisms for nausea and vomiting to create a new antiemetic therapy.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of hunger and satiety signalling pathway from peripheral to central nervous system using visualizing technology of a marker of neuronal activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of neuronal activity, a molecular basis and a behavioral change related to chemoreceptor-mediated nausea and emesis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neuromodulatory effects of feeding signasl in GLP-1 releasing neurons of the brainstemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological analysis of GLP-1 releasing neurons in the brainstemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of intraperitoneally administered L-histidine on food intake, taste, and visceral sensation in rats2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Movement-related cortical magnetic fields associated with self-paced tongue protrusion in humans2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs.2011

Author(s)

Journal Title

Data Source

[Journal Article] Glucagon-like peptide 1 and the brain: central actions -central sources?2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCK stimulation of GLP-1 neurons involves a_1-adrenoceptor-mediated increase in glutamatergic synaptic inputs2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] Behavioral study on nausea induction by serotonin agonists in rats.2020

Author(s)

Organizer

Data Source

[Presentation] Effects of vagotomy and lesions of the area postrema on nausea induced by tranexamic acid.2019

Author(s)

Organizer

Data Source

[Presentation] Effects of vagotomy and area postrema lesion on induction of emesis by emetine.2019

Author(s)

Organizer

Data Source

[Presentation] Analysis of nausea induced by emetine or cisplatin in rats.2019

Author(s)

Organizer

Data Source

[Presentation] エメチン誘発の悪心に対する迷走神経切除と最後野損傷の影響2018

Author(s)

Organizer

Data Source

[Presentation] トラネキサム酸の悪心・嘔吐誘発機序の解析2018

Author(s)

HISADOME Kazunari 久留和成