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FUKUZUMI Takeo  福澄 岳雄

ORCIDConnect your ORCID iD *help
Researcher Number 00592768
Affiliation (based on the past Project Information) *help 2012 – 2014: 大阪大学, 産業科学研究所, 特任助教
Review Section/Research Field
Principal Investigator
Chemical biology
Except Principal Investigator
Bio-related chemistry / Chemical biology
Keywords
Principal Investigator
分子間相互作用解析 / ケミカルバイオロジー / SPR / 表面プラズモン共鳴 / ライブラリー / スクリーニング / 分子間相互作用 / ディスプレイスメントアッセイ / RNA
Except Principal Investigator
低分子 … More / 電荷移動錯体 / loop / pre-miRNA / 阻害 / Dicer / 構造変化 / ループ / 結合分子 / マイクロRNA / インビトロセレクション / 8位置換プリン / ライブラリー / 8位置換プリン化合物 / doped library / リボスイッチ / in vivo セレクション / 8位置換プリン誘導体 / reengineering / riboswitch / chemical library / 8-substituted purine / synthesis Less
  • Research Projects

    (3 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (6 People)
  •  Determination of molecular mechanism of loop-specific structural change and inhibitory effect for Dicer mediated reaction

    • Principal Investigator
      NAKATANI Kazuhiko
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Bio-related chemistry
    • Research Institution
      Osaka University
  •  プレマイクロRNA29aを標的とした分子設計指針の導出Principal Investigator

    • Principal Investigator
      福澄 岳雄
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Chemical biology
    • Research Institution
      Osaka University
  •  Synthesis of 8-substituted purine chemical library and riboswitch-reengineering

    • Principal Investigator
      NAKATANI Kazuhiko
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemical biology
    • Research Institution
      Osaka University

All 2013 2012 Other

All Journal Article Presentation Other

  • [Journal Article] Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules.2013

    • Author(s)
      Asako Murata, Takeo Fukuzumi, Shiori Umemoto, Kazuhiko Nakatani
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 23 Issue: 1 Pages: 252-255

    • DOI

      10.1016/j.bmcl.2012.10.108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-24710262
  • [Journal Article] Fluorescent indicator displacement assay of ligands targeting 10 microRNA precursors2013

    • Author(s)
      Murata, A.; Harada, Y.; Fukuzumi, T.; Nakatani, K.
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 21 Issue: 22 Pages: 7101-7106

    • DOI

      10.1016/j.bmc.2013.09.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-25750393
  • [Journal Article] Structure-activity studies on the fluorescent indicator in the displacement assay for the screening of small molecules binding to RNA2012

    • Author(s)
      Umemoto, S.; Im, S.; Zhang, J.; Hagihara, M.; Murata, A.; Harada, Y.; Fukuzumi, T.; Wazaki, T.; Sasaoka, S.; Nakatani, K.
    • Journal Title

      Chem. Eur. J.

      Volume: 18 Pages: 9999-10008

    • Data Source
      KAKENHI-PROJECT-23241073
  • [Journal Article] Structure-activity studies on the fluorescent indicator in the displacement assay for the screening of small molecules binding to RNA.2012

    • Author(s)
      Shiori Umemoto, Seongwang Im, Jinhua Zhang, Masaki Hagihara, Asako Murata, Yasue Harada, Takeo Fukuzumi, Takahiro Wazaki, Shin-ichi Sasaoka, and Kazuhiko Nakatani
    • Journal Title

      Chemistry A European Journal

      Volume: 18 Issue: 32 Pages: 9999-10008

    • DOI

      10.1002/chem.201103932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-24710262
  • [Presentation] HIV-1 mRNAの部分構造RREと低分子の相互作用解析2013

    • Author(s)
      津田哲哉・福澄岳雄・中谷和彦
    • Organizer
      日本ケミカルバイオロジー学会 第8回年会
    • Place of Presentation
      東京医科歯科大学
    • Data Source
      KAKENHI-PROJECT-25620134
  • [Presentation] マイクロRNA前駆体を標的とした小分子ライブラリーの合成と評価2013

    • Author(s)
      福澄岳雄・村田亜沙子・原田恭枝・梅本詩織・中谷和彦
    • Organizer
      日本薬学会年会 第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24710262
  • [Presentation] Synthesis of Small Molecule Library for pre-miRNA29a2012

    • Author(s)
      Takeo Fukuzumi, Asako Murata, Yasue Harada, Kazuhiko Nakatani
    • Organizer
      IKCOC12
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-24710262
  • [Presentation] Coumarin derivatives as an indicator for interactions between RNA and small molecules2012

    • Author(s)
      T. Tsuda, T. Fukuzumi, K. Nakatani
    • Organizer
      The 7th Asia and Oceania Conference on Photochemistry 2012
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23241073
  • [Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures2012

    • Author(s)
      T. Fukuzumi, A. Murata, Y. Harada, K. Nakatani
    • Organizer
      RNA 2012, the 17th Annual Meeting of the RNA Society
    • Place of Presentation
      ミシガン大学 USA
    • Data Source
      KAKENHI-PROJECT-23241073
  • [Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures2012

    • Author(s)
      Takeo Fukuzumi, Asako Murata, Yasue Harada, Kazuhiko Nakatani
    • Organizer
      RNA 2012 The 17th Annual Meeting of the RNA Society
    • Place of Presentation
      Ann Arbor, Michigan, USA
    • Data Source
      KAKENHI-PROJECT-24710262
  • [Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures2012

    • Author(s)
      T. Fukuzumi, A. Murata, Y. Harada, K. Nakatani
    • Organizer
      IKCOC-12
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23241073
  • [Presentation] HIV-1 mRNAの部分構造RREと低分子の相互作用解析

    • Author(s)
      津田哲哉・福澄岳雄・中谷和彦
    • Organizer
      日本ケミカルバイオロジー学会 第8回年会
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2013-06-19 – 2013-06-21
    • Data Source
      KAKENHI-PROJECT-23241073
  • [Presentation] Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing

    • Author(s)
      Asako Murata, Ayako Sugai, Takeo Fukuzumi, Shiori Umemoto, Chikara Dohno, Kazuhiko Nakatani
    • Organizer
      RNA 2013, the 18th Annual Meeting of the RNA Society
    • Place of Presentation
      Congress Center Davos, Davos, Switzerland
    • Year and Date
      2013-06-11 – 2013-06-16
    • Data Source
      KAKENHI-PROJECT-23241073
  • [Presentation] Coumarin fluorochrome binds to Rev responsible element RNA with extremely large absorption shift

    • Author(s)
      Tetsuya Tsuda, Takeo Fukuzumi, Kazuhiko Nakatani
    • Organizer
      RNA 2013, the 18th Annual Meeting of the RNA Society
    • Place of Presentation
      Congress Center Davos, Davos, Switzerland
    • Year and Date
      2013-06-11 – 2013-06-16
    • Data Source
      KAKENHI-PROJECT-23241073
  • []

  • 1.  NAKATANI Kazuhiko (70237303)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 2.  TAKEI Fumie (30252711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  HAGIHARA Masaki (40403000)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  DOHNO Chikara (60420395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  MURATA Asako (50557121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 6.  AIKAWA Haruo (70547322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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