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Kuroshima Takeshi  黒嶋 雄志

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KUROSHIMA Takeshi  黒嶋 雄志

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Researcher Number 00610669
Other IDs
Affiliation (Current) 2025: 東京科学大学, 大学院医歯学総合研究科, 助教
Affiliation (based on the past Project Information) *help 2017 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 助教
2016: 北海道大学, 歯学研究科, 助教
2012: 北海道大学, 大学院・歯学研究科, 専門研究員
2012: 北海道大学, 歯学研究科(研究院), 専門研究員
2011: 北海道大学, 大学病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related / Pathobiological dentistry/Dental radiology / Surgical dentistry
Keywords
Principal Investigator
口腔がん / Sam68 / 遠隔転移 / 中心性骨内癌 / 顎骨中心性癌 / 原発性骨内癌 / 上皮間葉移行 / RBP / 口腔扁平上皮癌 / mRNP granules … More / mRNA / RNA結合タンパク質 / 頸部リンパ節転移 / 扁平上皮癌 / 蛋白質 / 細胞・組織 / 癌 / RNA結合タンパク / PP32r1 / HuR / pp32r1 / pp32 / ARE-mRNA Less
  • Research Projects

    (4 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (4 People)
  •  原発性骨内癌の病態解明による新規診断技術・革新的治療法開発の基盤構築研究Principal Investigator

    • Principal Investigator
      黒嶋 雄志
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Medical and Dental University
  •  The function of RNA binding proteins and messenger ribonucleoprotein granules in oral squamous cell carcinomaPrincipal Investigator

    • Principal Investigator
      Kuroshima Takeshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Efficacy of mRNA-binding protein Sam68 as new biomarker and therapeutic target in oral squamous cell carcinomaPrincipal Investigator

    • Principal Investigator
      Kuroshima Takeshi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical and Dental University
      Hokkaido University
  •  Failure of ARE-nRNA control causes oncogenesis of oral cancerPrincipal Investigator

    • Principal Investigator
      KUROSHIMA Takeshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Surgical dentistry
    • Research Institution
      Hokkaido University

All 2022 2021 2019 2012 2011

All Journal Article Presentation

  • [Journal Article] High expression of Sam68 contributes to metastasis by regulating vimentin expression and a motile phenotype in oral squamous cell carcinoma2022

    • Author(s)
      Komiyama Takuya、Kuroshima Takeshi、Sugasawa Takehito、Fujita Shin-Ichiro、Ikami Yuta、Hirai Hideaki、Tsushima Fumihiko、Michi Yasuyuki、Kayamori Kou、Higashino Fumihiro、Harada Hiroyuki
    • Journal Title

      Oncology Reports

      Volume: 48 Issue: 4

    • DOI

      10.3892/or.2022.8398

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10133
  • [Journal Article] Metastasis of lower gingival squamous cell carcinoma to buccinator lymph node: case report and review of the literature2019

    • Author(s)
      Takada Kaho、Kuroshima Takeshi、Shimamoto Hiroaki、Ohsako Toshimitsu、Kayamori Kou、Ikeda Tohru、Harada Hiroyuki
    • Journal Title

      World Journal of Surgical Oncology

      Volume: 17 Issue: 1 Pages: 1-5

    • DOI

      10.1186/s12957-019-1559-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K20433
  • [Journal Article] Viral - mediated sta bilization of AU - rich element containing mRNA contributes to cell transformation2011

    • Author(s)
      Kuroshima T , Aoyagi M , Yasuda M , Kitamura T,他6名
    • Journal Title

      Oncogene

      Volume: 30(26) Issue: 26 Pages: 2912-20

    • DOI

      10.1038/onc.2011.14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592237, KAKENHI-PROJECT-23659929, KAKENHI-PROJECT-23792138, KAKENHI-PROJECT-23890010
  • [Presentation] 舌扁平上皮癌におけるSam68の役割2021

    • Author(s)
      込山拓也、黒嶋雄志、原田浩之
    • Organizer
      第75回 日本口腔科学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K10133
  • [Presentation] Contralateral cervical lymph node metastases in tongue squamous cell carcinoma.2019

    • Author(s)
      Takeshi KUROSHIMA, Yasuyuki MICHI, Hiroaki SHIMAMOTO, Hirofumi TOMIOKA, Hideaki HIRAI, Takuma KUGIMOTO, Yumi MOCHIZUKI, Kae TANAKA and Hiroyuki HARADA.
    • Organizer
      7th WORLD CONGRESS of the International Academy of Oral Oncology.
    • Data Source
      KAKENHI-PROJECT-16K20433
  • [Presentation] アデノウイルス感染によるP-bodiesの変化はARE-mRNAの分解に影響する2012

    • Author(s)
      柳川-松田彩、黒嶋雄志、安田元昭、北村哲也、進藤正信、東野史裕
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡、福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-23890010
  • [Presentation] アデノウイルス感染は宿主細胞のP-Bodiesに特異的な変化をもたらす2012

    • Author(s)
      柳川-松田彩、東野史裕、黒嶋雄志、安田元昭、北村哲也、進藤正信
    • Organizer
      第92回北海道医学大会病理分科会
    • Place of Presentation
      札幌、札幌医大
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-23890010
  • [Presentation] アデノウイルス感染がもたらす宿主細胞P-bodyの変化2012

    • Author(s)
      柳川-松田彩、黒嶋雄志、北村哲也、東野史裕、進藤正信
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京、京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-23890010
  • [Presentation] ARE-mRNAの安定化は細胞がん化を誘導する2011

    • Author(s)
      黒嶋雄志
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Year and Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-23890010
  • [Presentation] Stabilization of AU-rich element containing mRNA mediated by adenovirus gene product contributes to cell transformation2011

    • Author(s)
      Kuroshima T.,Yasuda M., Kitamura T., Yanagawa-Matsuda A., Shindoh M. and Higashino F
    • Organizer
      IUMS 2011 (International Union of Microbiological Societies 2011Congress)
    • Place of Presentation
      Sapporo, JAPAN
    • Year and Date
      2011-09-14
    • Data Source
      KAKENHI-PROJECT-23890010
  • [Presentation] ARE-mRNAを安定化させることは細胞のがん化に寄与する2011

    • Author(s)
      黒嶋雄志
    • Organizer
      第65回日本口腔科学会学術総会
    • Place of Presentation
      東京、タワーホール船堀
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-23890010
  • [Presentation] Modulation of P bodies and stress granules in adenovirus infected cells2011

    • Author(s)
      Kuroshima T., Kitamura T.,Yanagawa-Matsuda A., Shindoh M. and Higashino F
    • Organizer
      RNA 2011 (Sixteenth Annual Meeting of the RNA Society)
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-23890010
  • [Presentation] アデノウイルス感染細胞でのRNP顆粒構造の挙動2011

    • Author(s)
      東野史裕、黒嶋雄志、北村哲也、柳川-松田彩、進藤正信
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      札幌、北海道大学
    • Year and Date
      2011-06-28
    • Data Source
      KAKENHI-PROJECT-23890010
  • 1.  東野 史裕 (50301891)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  北村 哲也 (00451451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  栢森 高 (10569841)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  菅澤 威仁 (60821840)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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