Hatakeyama Hiroyasu 畠山裕康

Researcher Number	00619067
Other IDs	https://orcid.org/0000-0002-5215-1295
Affiliation (Current)	2024: 北里大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 北里大学, 医学部, 准教授 2020 – 2021: 北里大学, 医学部, 講師 2017 – 2018: 北里大学, 医学部, 講師 2014 – 2015: 東北大学, 学際科学フロンティア研究所, 助教 2013: 東北大学, 医工学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Biomedical structure and function and related fields / Nanomaterials chemistry / General physiology Except Principal Investigator Basic Section 48020:Physiology-related / Pathological medical chemistry
Keywords	Principal Investigator インスリン / 一分子計測 / 量子ドット / アクチン / 細胞骨格系 / イメージング / 細胞機能制御 / ナノ粒子 / ライブイメージング / 糖輸送体 … More Except Principal Investigator … More インスリン / 糖尿病 / シナプス小胞 / 膵内分泌 / 蛍光標識 / 細胞内小器官 / 内分泌細胞 / ホルモン分泌 / 単分子イメージング / 細胞骨格 / アクチン / 細胞生理 / 蛍光画像 / 顕微鏡 / 細胞内運動 / 分泌顆粒 / イメージング / 蛍光色素 / 共焦点顕微鏡 / 蛍光 / 膵島 / 内分泌 / アディポカイン / マイオカイン / 脂肪細胞 / 細胞内小胞輸送系 / インスリン抵抗性 / GLUT4 / 小胞輸送 / ソーティング / 骨格筋 / インスリン反応性 / ソーティング障害 / 生活習慣病 Less

Analysis of glucose actions and the roles of F-actin on intracellular insulin granule behaviorPrincipal Investigator
- Principal Investigator
  
  畠山裕康
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kitasato University
膵内分泌組織のシナプス小胞様顆粒の動態と微細構造の解明
- Principal Investigator
  
  高橋倫子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kitasato University
インスリン分泌顆粒の動員過程を制御するしくみの定量理解Principal Investigator
- Principal Investigator
  
  畠山裕康
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kitasato University
Quantification of dynamics of secretory granules and study of regulatory mechanism
- Principal Investigator
  
  Takahashi Noriko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kitasato University
Attempts for generating intracellular artificial protein complexes and modulating cellular functions with fluorescent nanoparticlesPrincipal Investigator
- Principal Investigator
  
  Hatakeyama Hiroyasu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical structure and function and related fields
- Research Institution
  Kitasato University
Establishement of simplified methods for analyzing intracellular single molecule behaviorPrincipal Investigator
- Principal Investigator
  
  Hatakeyama Hiroyasu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nanomaterials chemistry
- Research Institution
  Tohoku University
Molecular and structural basis of insulin resistance revealed by high precision nanometryPrincipal Investigator
- Principal Investigator
  
  Hatakeyama Hiroyasu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Tohoku University
Investigation of the Vps10p-family proteins and its sorting disorders in life-style-related diseases
- Principal Investigator
  
  Kanzaki Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University

All 2023 2022 2021 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Single quantum dot tracking reveals that an individual multivalent 2 HIV-1 Tat-protein transduction domain can activate machinery for 3 lateral transport and endocytosis2013
- Author(s)
  3.Yasuhiro Suzuki*, Chandra Nath Roy, Warunya Promjunyaku, Hiroyasu Hatakeyama, Kohsuke Gonda, Junji Imamura, Biju Vasudevan Pillai, Noriaki Ohuchi, Makoto Kanzaki , Hideo Higuchi, and Mitsuo Kaku
- Journal Title
  
  Mol. Cell Biol.
  
  Volume: 33 Issue: 15 Pages: 3039-3049
- DOI
  10.1128/mcb.01717-12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23107002, KAKENHI-PLANNED-23107009, KAKENHI-PROJECT-23247022, KAKENHI-PROJECT-25293074, KAKENHI-PROJECT-25713010
[Journal Article] Development of dual-color simultaneous single molecule imaging system for analyzing multiple intracellular trafficking activities2013
- Author(s)
  Hatakeyama H, Kanzaki M.
- Journal Title
  
  Conf Proc IEEE Eng Med Biol Soc.
  
  Volume: 2013 Pages: 1418-1421
- DOI
  10.1109/embc.2013.6609776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293074, KAKENHI-PROJECT-25713010
[Presentation] Roles of F-actin in intracellular insulin granule behavior analyzed by single-particle tracking2023
- Author(s)
  畠山裕康、小野新一郎、大嶋友美、高橋倫子
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] Live-imaging analysis of F-actin actions on intracellular insulin granule behavior2023
- Author(s)
  小野新一郎、畠山裕康、大嶋友美、高橋倫子
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] Roles of F-actin in intracellular insulin granule behavior analyzed by single-particle tracking2022
- Author(s)
  畠山　裕康、小野　新一郎、大嶋　友美、高橋　倫子
- Organizer
  第100回日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06773
[Presentation] 基礎医学から深める糖尿病学 ―インスリン分泌機構の研究―2022
- Author(s)
  高橋倫子、大嶋友美、安岡有紀子、畠山裕康
- Organizer
  第65回日本糖尿病学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] アクチン細胞骨格系によるインスリン分泌顆粒の細胞内動態調節2022
- Author(s)
  小野新一郎、畠山裕康、大嶋友美、雨木正憲、福田英一、高橋倫子
- Organizer
  第252回生理学東京談話会
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] Live-imaging analysis of F-actin actions on intracellular insulin granule behavior2022
- Author(s)
  小野　新一郎、畠山　裕康、大嶋　友美、高橋　倫子
- Organizer
  第100回日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06773
[Presentation] Single-molecule analysis for cytoskeletal dependence of intracellular insulin granule behavior2022
- Author(s)
  畠山　裕康、大嶋　友美、小野　新一郎、高橋　倫子
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06773
[Presentation] アクチン細胞骨格系によるインスリン分泌顆粒の細胞内挙動調節2022
- Author(s)
  小野　新一郎、畠山　裕康、大嶋　友美、福田　英一、高橋　倫子
- Organizer
  第252回生理学東京談話会
- Data Source
  KAKENHI-PROJECT-21K06773
[Presentation] インスリン分泌現象の可視化解析2022
- Author(s)
  高橋倫子、畠山裕康、大嶋友美、小野新一郎、福田英一、河西春郎
- Organizer
  第252回生理学東京談話会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] インスリン分泌現象の可視化と解析2022
- Author(s)
  高橋　倫子、畠山　裕康、大嶋　友美
- Organizer
  第95回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] Single molecule analysis of insulin granule movement within pancreatic β-cells2021
- Author(s)
  畠山裕康、大嶋友美、高橋倫子
- Organizer
  第126回日本解剖学会総会・全国学術集会／第98回日本生理学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] Signaling in islet hormone secretion-physiology and pathophysiology- Imaging analysis of granule dynamics within insulin-secreting cells2021
- Author(s)
  畠山裕康、大嶋友美、高橋倫子
- Organizer
  第64回日本糖尿病学会年次学術集会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] インスリン分泌顆粒の細胞内挙動の可視化計測2021
- Author(s)
  畠山裕康、大嶋友美、高橋倫子
- Organizer
  第251回生理学東京談話会
- Data Source
  KAKENHI-PROJECT-20K07280
[Presentation] インスリン分泌顆粒の細胞内挙動の可視化計測2021
- Author(s)
  畠山　裕康、大嶋　友美、高橋　倫子
- Organizer
  第251回生理学東京談話会
- Data Source
  KAKENHI-PROJECT-21K06773
[Presentation] Imaging analyis of granule dynamics within insulin-secreting cells2021
- Author(s)
  畠山　裕康、大嶋　友美、高橋　倫子
- Organizer
  第64回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06773
[Presentation] 細胞内一分子計測に基づく生理機能の理解を目指して2021
- Author(s)
  畠山　裕康
- Organizer
  次世代研究者シンポジウム2021
- Data Source
  KAKENHI-PROJECT-21K06773
[Presentation] The Human Satellite Cells can Form the Myotube Even in the Atrophic Fatty Muscle of Rotator Cuff Tear2016
- Author(s)
  Koide M, Hagiwara Y, Ando A, Yabe Y, Kanazawa K, Sekiguchi T, Itaya N, Yoshida S, Itoi E, Kanzaki M, Hatakeyama H, Tsuchiya M
- Organizer
  Orthopaedic Research Society 2016 Annual Meeting
- Place of Presentation
  Orland, Florida, USA
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] マウス走行運動モデルと電気パルス強収縮モデルを用いた収縮骨格筋の生物学的応答の解析―GLUT4制御に関わる分子基盤について―2016
- Author(s)
  細谷　雅浩、堰合　茂智、畠山　裕康、神崎　展
- Organizer
  第4回骨格筋生物学研究会
- Place of Presentation
  松本
- Year and Date
  2016-03-01
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] マウス走行運動モデルと電気パルス強収縮モデルを用いた収縮骨格筋の生物学的応答の解析―GLUT4制御に関わる分子基盤について―2016
- Author(s)
  細谷　雅浩、堰合　茂智、畠山　裕康、神崎　展
- Organizer
  第4回骨格筋生物学研究会
- Place of Presentation
  松本大学，長野
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Involvement of Mechanosensitive Transcriptional Network in Contraction-dependent Muscle Fiber Type Conversion Analyzed using the "in vitro Exercise Model"2015
- Author(s)
  Hosoya M, Uda Y, Hatakeyama H, Kanzaki M
- Organizer
  Cell Symposia "Exercise Metabolism"
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2015-07-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] AS160 and Tbc1d1 as a determinant of insulin sensitivity in GLUT4 trafficking2015
- Author(s)
  Hatakeyama H, Kanzaki M
- Organizer
  FASEB SRC "Glucose Transport: Gateway to Metabolic Systems Biology"
- Place of Presentation
  Big Sky, MT, USA
- Year and Date
  2015-07-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Coordinated actions of AS160 and Tbc1d1 as a determinant of insulin sensitivity in GLUT4 trafficking2015
- Author(s)
  Hiroyasu Hatakeyama, Makoto Kanzaki
- Organizer
  FASEB SRC "Glucose Transport: Gateway to Metabolic Systems Biology"
- Place of Presentation
  ビッグスカイ（アメリカ・モンタナ州）
- Year and Date
  2015-07-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] AS160 vs Tbc1d1: Cooperative determination of insulin-responsive GLUT4 trafficking activity after exercise-mimetic stimuli2015
- Author(s)
  Hatakeyama H, Kanzaki M
- Organizer
  51st Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Involvement of Mechanosensitive Transcriptional Network in Contraction-dependent Muscle Fiber Type Conversion Analyzed using the "in vitro Exercise Model"2015
- Author(s)
  Masahiro Hosoya, Yuhei Uda, Hiroyasu Hatakeyama, Makoto Kanzaki
- Organizer
  Cell Symposia "Exercise Metabolism"
- Place of Presentation
  アムステルダム（オランダ）
- Year and Date
  2015-07-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] 一分子計測で迫る糖輸送体分子の細胞内輸送システム2015
- Author(s)
  畠山　裕康
- Organizer
  東海大学マイクロ・ナノ研究開発センター第14回講演会、バイオイメージングセミナー
- Place of Presentation
  平塚
- Year and Date
  2015-08-03
- Invited
- Data Source
  KAKENHI-PROJECT-26600019
[Presentation] AS160 vs Tbc1d1: Cooperative determination of insulin-responsive GLUT4 trafficking activity after exercise-mimetic stimuli2015
- Author(s)
  Hiroyasu Hatakeyama, Makoto Kanzaki
- Organizer
  51st Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  ストックホルム（スウェーデン）
- Year and Date
  2015-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] 一分子計測で迫る糖輸送体分子の細胞内輸送システム2015
- Author(s)
  畠山　裕康
- Organizer
  東海大学マイクロ・ナノ研究開発センター第14回講演会、バイオイメージングセミナー
- Place of Presentation
  平塚
- Year and Date
  2015-08-03
- Invited
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] GLUT4一分子挙動計測に基づくTBC/RabGAPsが司る運動効果の分子基盤解析2015
- Author(s)
  畠山　裕康、神崎　展
- Organizer
  第3回骨格筋生物学研究会
- Place of Presentation
  仙台
- Year and Date
  2015-03-07
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] Cellular Nanoscience and Exercise-induced Health Benefits2015
- Author(s)
  Kanzaki M, Hatakeyama H
- Organizer
  International Conference on Fluid Dynamics 2015 “Advanced Physical Stimuli and Biological Responses”
- Place of Presentation
  Sendai, International Center
- Year and Date
  2015-10-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] インスリン応答性GLUT4輸送制御におけるTBC1D family Rab GTPase活性化タンパク質群の機能解析2014
- Author(s)
  畠山　裕康、神崎　展
- Organizer
  第57回日本糖尿病学会年時学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] Submissive Role of AS160 in Tbc1d1-mediated GLUT4 Trafficking Activation in response to Ca2+ and Insulin2014
- Author(s)
  Hiroyasu Hatakeyama, Makoto Kanzaki
- Organizer
  74th Science Sessions of the American Diabetes Association
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2014-06-16
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] Tbc1d1が示すインスリン不応性およびインスリン応答性GLUT4輸送制御とその遷移による「インスリン応答性獲得」の分子基盤2013
- Author(s)
  畠山　裕康, 神崎　展
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本、熊本
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Intracellular trafficking nanometry for quantifying GLUT4 translocation2013
- Author(s)
  Hatakeyama H, Kanzaki M
- Organizer
  FASEB Science Research Conference "Glucose transport: Gateway for metabolic systems biology"
- Place of Presentation
  Snowmass Village, CO, USA
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] Intracellular trafficking nanometry for quantifying GLUT4 translocation2013
- Author(s)
  Hatakeyama H. and Kanzaki M.
- Organizer
  FASEB Science Research Conferences
- Place of Presentation
  Snowmass Village, CO, USA
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Establishment of intracellular trafficking nanometry in single isolated myofibers2013
- Author(s)
  Kaita S., Shinagawa R., Hatakeyama H. and Kanzaki M.
- Organizer
  2013 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  The New Orleans Ernest N. Morial Convention Center, USA
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Comprehensive viewing of intracellular trafficking activities based on single molecule imaging2013
- Author(s)
  Hatakeyama H. and Kanzaki M
- Organizer
  2013 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  The New Orleans Ernest N. Morial Convention Center, USA
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Molecular basis of Tbc1d1 for acquiring temporal insulin-responsive ability triggering GLUT4 translocation2013
- Author(s)
  Hatakeyama H. and Kanzaki M.
- Organizer
  73rd Scientific Session of the American Diabetes Association
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Development of dual-color simultaneous single molecule imaging system for analyzing multiple intracellular trafficking activities2013
- Author(s)
  Hatakeyama H. and Kanzaki M.
- Organizer
  35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
- Place of Presentation
  Osaka International Convention Center, Osaka
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] 運動依存性GLUT4トランスロケーション機構の解析―電気パルス刺激によるマウス骨格筋の強収縮モデルを用いた試み
- Author(s)
  細谷雅浩・畠山裕康・土谷昌広・神崎　展
- Organizer
  第3回骨格筋生物学研究会
- Place of Presentation
  仙台・東北大学星陵キャンパス
- Year and Date
  2015-03-07 – 2015-03-09
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Establishment of intracellular trafficking nanometry in single isolated myofibers.
- Author(s)
  Kaita S, Shinagawa R, Hatakeyama H, Kanzaki M
- Organizer
  American Society for Cell Biology 2013 Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] Tbc1d1が示すインスリン不応性およびインスリン応答性GLUT4輸送制御とその遷移による「インスリン応答性獲得」の分子基盤
- Author(s)
  畠山　裕康、神崎　展
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] GLUT4一分子挙動計測に基づくTBC/RabGAPsが司る運動効果の分子基盤解析
- Author(s)
  畠山裕康，神崎　展
- Organizer
  第3回骨格筋生物学研究会
- Place of Presentation
  仙台・東北大学星陵キャンパス
- Year and Date
  2015-03-07 – 2015-03-09
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Comprehensive viewing of intracellular trafficking activities based on single molecule imaging
- Author(s)
  Hatakeyama H, Kanzaki M
- Organizer
  American Society for Cell Biology 2013 Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] Molecular basis of Tbc1d1 for acquiring temporal insulin-responsive ability triggering GLUT4 translocation
- Author(s)
  Hatakeyama H, Kanzaki M
- Organizer
  American Diabetes Association's 73rd Scientific Session
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] 一分子イメージングに基づく細胞内輸送システムの定量計測
- Author(s)
  畠山　裕康、神崎　展
- Organizer
  バイオイメージインフォマティクス2014
- Place of Presentation
  岡崎
- Year and Date
  2014-06-09 – 2014-06-10
- Data Source
  KAKENHI-PROJECT-26600019
[Presentation] Submissive Role of AS160 in Tbc1d1-mediated GLUT4 Trafficking Activation in Response to Ca2+ and Insulin
- Author(s)
  Hiroyasu Hatakeyama, Makoto Kanzaki
- Organizer
  74th American Diabetes Association Scientific Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-06-16 – 2014-06-18
- Data Source
  KAKENHI-PROJECT-25293074
[Presentation] Development of dual-color simultaneous single molecule imaging system for analyzing multiple intracellular trafficking activities.
- Author(s)
  Hatakeyama H, Kanzaki M
- Organizer
  35th Annual International Conference of IEEE Eng Med Biol Soc
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] 分子動態に基づく細胞内輸送システムの定量解析
- Author(s)
  畠山　裕康
- Organizer
  北海道大学電子科学研究所　第2回蛍光ミニシンポジウム
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-25713010
[Presentation] 一分子イメージングに基づく細胞内輸送システムの定量計測
- Author(s)
  畠山　裕康、神崎　展
- Organizer
  バイオイメージインフォマティクス2014
- Place of Presentation
  岡崎
- Year and Date
  2014-06-09 – 2014-06-10
- Data Source
  KAKENHI-PROJECT-25713010

1. Takahashi Noriko (60332178)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. Kanzaki Makoto (10272262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
3. 樋口秀男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hatakeyama Hiroyasu 畠山 裕康

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Analysis of glucose actions and the roles of F-actin on intracellular insulin granule behaviorPrincipal Investigator

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膵内分泌組織のシナプス小胞様顆粒の動態と微細構造の解明

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インスリン分泌顆粒の動員過程を制御するしくみの定量理解Principal Investigator

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Quantification of dynamics of secretory granules and study of regulatory mechanism

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Attempts for generating intracellular artificial protein complexes and modulating cellular functions with fluorescent nanoparticlesPrincipal Investigator

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Establishement of simplified methods for analyzing intracellular single molecule behaviorPrincipal Investigator

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Molecular and structural basis of insulin resistance revealed by high precision nanometryPrincipal Investigator

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Investigation of the Vps10p-family proteins and its sorting disorders in life-style-related diseases

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[Journal Article] Single quantum dot tracking reveals that an individual multivalent 2 HIV-1 Tat-protein transduction domain can activate machinery for 3 lateral transport and endocytosis2013

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[Journal Article] Development of dual-color simultaneous single molecule imaging system for analyzing multiple intracellular trafficking activities2013

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[Presentation] Roles of F-actin in intracellular insulin granule behavior analyzed by single-particle tracking2023

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[Presentation] Live-imaging analysis of F-actin actions on intracellular insulin granule behavior2023

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[Presentation] Roles of F-actin in intracellular insulin granule behavior analyzed by single-particle tracking2022

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[Presentation] 基礎医学から深める糖尿病学 ―インスリン分泌機構の研究―2022

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[Presentation] アクチン細胞骨格系によるインスリン分泌顆粒の細胞内動態調節2022

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Hatakeyama Hiroyasu 畠山裕康