Kirino Kosuke 桐野浩輔

Researcher Number	00621707
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 臨床研究センター, 専門職
Affiliation (based on the past Project Information) *help	2022 – 2023: 九州大学, 大学病院, その他 2018 – 2021: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 58070:Lifelong developmental nursing-related / Pediatric surgery
Keywords	Principal Investigator ゲノム編集 / 発がん / 神経芽種 / CRSPR/Cas9 / iPS細胞 / ES細胞 / 小児外科学 / 交感神経細胞 / ヒト多能性幹細胞 / MYCN増幅 / 染色体異常 / 神経芽腫 … More Except Principal Investigator … More ヒルシュスプルング病類縁疾患 / 慢性特発性偽性腸閉塞症 / 腸管神経節細胞僅少症 / MMIHS / 腸管不全 / ヒルシュスプルング病 / 再生医療 / 間葉系細胞 / ヒト乳歯歯髄幹細胞 / 腸管神経節細胞 / 性分化疾患 / 性機能障害 / 総排泄腔疾患 / 総排泄腔遺残症 / 移行期医療 / 支援 / 当事者参加型 / 稀少難病 / アイデンティティ / トランジション / 移行期 / 難病 / 移行期支援 / 性交障害 / 当事者参加型研究 / ピアサポート / アクションリサーチ / 排泄障害 / 総排泄腔外反症 / 総排泄腔遺残 / 疾患モデル / zebrafish / 筋肉の発生機序 / 先天性横隔膜ヘルニア / 横隔膜ヘルニア / microinjection / LMOD1 / ゼブラフィッシュ / ACTG2遺伝子 / CIIP / hypoganglionosis / 電気生理学 / 乳歯幹細胞 / 指定難病 / 組織工学 / 細胞移植 / 乳歯幹細胞学 / 再生医療学 / 小児外科学 / 歯学 / 細胞・組織 / 再生医学 / 移植・再生医療 / 腸管蠕動不全 / 幹細胞 Less

Creation of abnormal muscle development model of zebrafish and novel drug platform
- Principal Investigator
  
  KONDO Takuya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
How do female patients with excretory disorders live as women?
- Principal Investigator
  
  MIYATA Junko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Kyushu University
乳歯歯髄幹細胞によるヒルシュスプルング病と類縁疾患の病因解明および根治療法の開発
- Principal Investigator
  
  田口智章
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukuoka College of Health Sciences
Modeling oncogenesis of neuroblastoma using human pluripotent stem cell-derived sypmathetic neuronsPrincipal Investigator
- Principal Investigator
  
  Kirino Kosuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
Identification and functional analysis of genetic mutations for novel therapies for allied disorders of Hirschsprung's disease
- Principal Investigator
  
  Kono Jun
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
Elucidation of the etiology and development of the novel therapy using stem cells from human exfoliated deciduous teeth for Hirschsprung's disease and its allied disorders
- Principal Investigator
  
  TAGUCHI Tomoaki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatric surgery
- Research Institution
  Kyushu University

All 2022 2021 2019 2018

All Journal Article Presentation

[Journal Article] Therapeutic potential of spheroids of stem cells from human exfoliated deciduous teeth for chronic liver fibrosis and hemophilia A.2019
- Author(s)
  Takahashi Y, Yuniartha R, Yamaza T, Sonoda S, Yamaza H, Kirino K, Yoshimaru K, Matsuura T, Taguchi T.
- Journal Title
  
  Pediatr Surg Int
  
  Volume: 35 Issue: 12 Pages: 1379-1388
- DOI
  10.1007/s00383-019-04564-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02682
[Journal Article] Acquired isolated hypoganglionosis as a distinct entity:results from a nationwide survey2019
- Author(s)
  Obata S, Yoshimau K, Kirino K, Izaki T,Ieiri S, Yamataka A, Koshinaga T, Iwai J, Ikeda H, Matsufuji H, Oda Y, Taguchi T
- Journal Title
  
  Pediatric Surgery International
  
  Volume: 35 Issue: 2 Pages: 215-220
- DOI
  10.1007/s00383-018-4398-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02682
[Journal Article] 小児外科領域における乳歯肝細胞を用いた再生医療2018
- Author(s)
  田口智章、吉丸耕一郎、栁佑典、張　秀英、桐野浩輔、山座孝義
- Journal Title
  
  周産期医学
  
  Volume: 48 Pages: 855-862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02682
[Journal Article] 小児短腸症候群・小腸機能不全の最前線　2．ヒルシュプスルング病およびその類縁疾患-成因から再生医療まで-2018
- Author(s)
  205吉丸耕一朗、桐野浩輔、栁佑典、河野雄紀、河野淳、入江敬子、髙橋良彰
- Journal Title
  
  日本外科学会雑誌
  
  Volume: 119 Pages: 616-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] 総排泄腔遺残症での適切な支援構築に向けた患者と医師のニーズに関するアンケート調査2022
- Author(s)
  宮田潤子, 小幡聡, 桐野浩輔, 木下義晶, 田尻達郎, 田口智章
- Organizer
  第59回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K10937
[Presentation] シンポジウム2：腸管神経再生;基礎研究から臨床応用まで「腸管神経再生の過去・現在・未来」2021
- Author(s)
  吉丸耕一朗、桐野浩輔、松浦俊治、田口智章
- Organizer
  第58回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21447
[Presentation] 患者の語りからみえた総排泄腔遺残症のトランジション医療問題と包括的支援策2021
- Author(s)
  宮田潤子、小幡　聡、桐野浩輔、入江敬子、大森淳子、伊崎智子、木下義晶、松浦俊治、田口智章
- Organizer
  第58回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K10937
[Presentation] Web会議システムの利用による総排泄腔遺残症/外反症におけるピアサポートの新たな可能性2021
- Author(s)
  宮田潤子, 濱田裕子, 藤田紋佳, 森口晴美, 川田紀美子, 小幡聡, 桐野浩輔, 林下里見, 三原優希, 植木慎悟, 木下義晶, 加藤聖子, 田尻達郎, 田口智章
- Organizer
  第31回日本小児外科QOL研究会
- Data Source
  KAKENHI-PROJECT-21K10937
[Presentation] Hirschsprung病類縁(H類縁)疾患患者を両親とする児の経過と周産期における問題点2019
- Author(s)
  髙橋良彰、吉丸耕一朗、栁佑典、松浦俊治、河野淳、桐野浩輔、江角元史郎、田口智章
- Organizer
  第31回日本小児小腸移植研究会
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] Biliary lineage of Hepatocyte-like cells derived from SHED (Stem Cells from Human Exfoliated Deciduous Teeth) in liver fibrosis mice2018
- Author(s)
  Takahashi Y, Yuniartha R,Yamaza T, Kirino K, Yanagi Y, Matsuura T, Taguchi T
- Organizer
  ISPSR2018
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] Radical innovative therapy for congenital isolated generalized hypoganglionosis using stem cells from human exfoliated deciduous teeth（SHED）2018
- Author(s)
  Yoshimaru K, Yamaza T, Kirino K, Esumi G, Izaki T, Taguchi T
- Organizer
  VCGT2018
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] Management of Hypoganglionosis2018
- Author(s)
  Taguchi T, Yoshimaru K, Kirino K, Esumi G, Izaki T
- Organizer
  ISPSR2018
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] Acquired Hypoganglionosis as a Distinct Entity: Results from a Nationwide Survey2018
- Author(s)
  Obata S, Yoshimaru K, Kirino K, Izaki T, Ieiri S, Yamataka A, Koshinaga S, Iwai J, Ikeda H, Taguchi T
- Organizer
  PCC25
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] Novel Therapy for Congenital Isolated Generalized Hypoganglionosis Using Mesenchymal Stem Cel2018
- Author(s)
  Taguchi T, Yoshimaru K, Kirino K, Esumi G, Izaki T
- Organizer
  PCC25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] Biliary lineage of Hepatocyte-like cells derived from mesenchymal stem cell（MSC）in liver fibrosis mice model.2018
- Author(s)
  Taguchi T, Yuniartha R, Yamaza T, Kirino K, Yoshimaru K, Yanagi Y, Matsuura T
- Organizer
  VCGT2018
- Data Source
  KAKENHI-PROJECT-16H02682
[Presentation] Effective spheroids transplantation of SHED (Stem cells from Human Exfoliated Deciduous Teeth) derived hepatocytes-like cells in liver fibrosis mice2018
- Author(s)
  Takahashi Y, Yuniartha R,Yamaza T, Kirino K, Yanagi Y, Matsuura T, Taguchi T
- Organizer
  ISPSR2018
- Data Source
  KAKENHI-PROJECT-16H02682

1. TAGUCHI Tomoaki (20197247)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. 吉丸耕一朗 (60711190)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. Kono Jun (90758418)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 松浦俊治 (10532856)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. 山座孝義 (80304814)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 山座治義 (30336151)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. 孝橋賢一 (10529879)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 梶岡俊一 (90274472)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 田尻達郎 (80304806)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 永田公二 (20419568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KONDO Takuya (00644725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIYATA Junko (20380412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 尾崎正雄 (10152472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 岡暁子 (60452778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大賀正一 (60233053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 黒田達夫 (60170130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 増本幸二 (20343329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 家入里志 (00363359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 木下義晶 (80345529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 柳佑典 (30596664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
21. 野中和明 (90128067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 高田英俊 (70294931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 奥野博庸 (70445310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中畑龍俊 (20110744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 濱田裕子 (60285541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 川田紀美子 (70709592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 藤田紋佳 (10437791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 森口晴美 (40835477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. 小幡聡 (30710975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. 植木慎悟 (10779218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 樗木晶子 (60216497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 松尾忠行 (00258584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 中園栄里 (10343732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. AKIYOSHI Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
35. 藤田綾佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kirino Kosuke 桐野 浩輔

Research Projects

Research Products

Co-Researchers

Creation of abnormal muscle development model of zebrafish and novel drug platform

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

How do female patients with excretory disorders live as women?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

乳歯歯髄幹細胞によるヒルシュスプルング病と類縁疾患の病因解明および根治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Modeling oncogenesis of neuroblastoma using human pluripotent stem cell-derived sypmathetic neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional analysis of genetic mutations for novel therapies for allied disorders of Hirschsprung's disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the etiology and development of the novel therapy using stem cells from human exfoliated deciduous teeth for Hirschsprung's disease and its allied disorders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Therapeutic potential of spheroids of stem cells from human exfoliated deciduous teeth for chronic liver fibrosis and hemophilia A.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acquired isolated hypoganglionosis as a distinct entity:results from a nationwide survey2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 小児外科領域における乳歯肝細胞を用いた再生医療2018

Author(s)

Journal Title

Data Source

[Journal Article] 小児短腸症候群・小腸機能不全の最前線 2．ヒルシュプスルング病およびその類縁疾患-成因から再生医療まで-2018

Author(s)

Journal Title

Data Source

[Presentation] 総排泄腔遺残症での適切な支援構築に向けた患者と医師のニーズに関するアンケート調査2022

Author(s)

Organizer

Data Source

[Presentation] シンポジウム2：腸管神経再生;基礎研究から臨床応用まで「腸管神経再生の過去・現在・未来」2021

Author(s)

Organizer

Data Source

[Presentation] 患者の語りからみえた総排泄腔遺残症のトランジション医療問題と包括的支援策2021

Author(s)

Organizer

Data Source

[Presentation] Web会議システムの利用による総排泄腔遺残症/外反症におけるピアサポートの新たな可能性2021

Author(s)

Organizer

Data Source

[Presentation] Hirschsprung病類縁(H類縁)疾患患者を両親とする児の経過と周産期における問題点2019

Author(s)

Organizer

Data Source

[Presentation] Biliary lineage of Hepatocyte-like cells derived from SHED (Stem Cells from Human Exfoliated Deciduous Teeth) in liver fibrosis mice2018

Author(s)

Kirino Kosuke 桐野浩輔

[Journal Article] 小児短腸症候群・小腸機能不全の最前線　2．ヒルシュプスルング病およびその類縁疾患-成因から再生医療まで-2018