Uehara Takayuki 上原貴行

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UEHARA Takayuki 上原貴行

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Researcher Number	00644402
Other IDs
Affiliation (Current)	2025: 琉球大学, 医学部, 委託非常勤講師 2025: 琉球大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 琉球大学, 医学部, 委託非常勤講師 2013 – 2019: 琉球大学, 医学部附属病院, 助教 2013: 琉球大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 頭頸部癌 / 分子標的治療 / 樹状細胞ワクチン治療 / 樹状細胞ワクチン / ヒト乳頭腫ウイルス / ヒト乳頭腫ウイルス（HPV） / mTOR / PI3K/Akt/ｍTOR経路 / Raptor / HPV関連頭頸部癌 … More / 細胞障害性T細胞 / 癌ワクチン治療 / 樹状細胞 / 頭頸部扁平上皮癌 / 免疫治療 … More Except Principal Investigator 頭頸部癌 / メチル化 / LCR / 放射線の敏感性 / E6とE7 / HPV / SMG-1 / DNAメチル化 / Long control region / 喉頭乳頭腫 / human papillomavirus / Epstein-Barr ウイルス / Epstein-Bar ウイルス / ヒト乳頭腫ウイルス / 予後 / 生活習慣 / 生物学的活性 / ウイルス感染 / アデノ随伴ウイルスベクター / 治療 / 頭頚部癌 / GALR2 / Ｇ蛋白共役受容体 / AAV / 癌抑制遺伝子 / GALR２ / 遺伝子治療 Less

Development of novel treatment targeting mTOR pathway Raptor in HPV-related head and neck cancerPrincipal Investigator
- Principal Investigator
  
  Uehara Takayuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
Efficacy of novel dendritic cell vaccine treatment for HPV-related cancerPrincipal Investigator
- Principal Investigator
  
  Uehara Takayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of the Ryukyus
Prediction of primary treatment outcome and prognosis by viral infection and tumor activity in head and neck cancer
- Principal Investigator
  
  Suzuki Mikio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of the Ryukyus
Analysis of carcinogenesis mechanism induced by human papillomavirus using DNA methylation as an indicator
- Principal Investigator
  
  Deng Zeyi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of the Ryukyus
Development of new immunotherapy using a dendritic cell in human papilloma virus-related head and neck cancerPrincipal Investigator
- Principal Investigator
  
  UEHARA Takayuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of the Ryukyus
Preclinical study for Head and Neck Cancer using rAAV-GALR2
- Principal Investigator
  
  KANAZAWA Takeharu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Jichi Medical University

All 2016 2015 2014 2012 Other

All Journal Article Presentation

[Journal Article] Branchiogenic carcinoma with high-risk-type human papillomavirus infection: A case report2016
- Author(s)
  Maeda H, Deng Z, Ikegami T, Matayoshi S, Agena S, Kiyuna A, Yamashita Y, Uehara T, Ganaha A, Suzuki M
- Journal Title
  
  Oncol Lett
  
  Volume: 12 Issue: 3 Pages: 2087-2091
- DOI
  10.3892/ol.2016.4907
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462611, KAKENHI-PROJECT-15K10816, KAKENHI-PROJECT-16K15722
[Journal Article] 【中咽頭癌-HPVの視点からみた大きな変化】疫学と病態　中咽頭癌と子宮頸癌のHPVの違いは?2016
- Author(s)
  鈴木幹男、上原貴行
- Journal Title
  
  JOHNS
  
  Volume: 32 Pages: 287-292
- Data Source
  KAKENHI-PROJECT-26462610
[Journal Article] Squamous cell carcinoma antigen as a diagnositic marker of nasal inverted papilloma2016
- Author(s)
  Yamashita Y, Hasegawa M, et al
- Journal Title
  
  Am J Rhinol Allergy
  
  Volume: 30 Issue: 2 Pages: 122-127
- DOI
  10.2500/ajra.2016.30.4287
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10785, KAKENHI-PROJECT-26462611, KAKENHI-PROJECT-15K10816
[Journal Article] Human papillomavurus infection and immunohisitochemical expression of cell cycle proteins pRb, p53, and p16(INK4a) in sinonasal diseases2015
- Author(s)
  Yamashita Y, Hasegawa M, et al
- Journal Title
  
  Infect Agent Cancer
  
  Volume: 10 Issue: 1 Pages: 23-23
- DOI
  10.1186/s13027-015-0019-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10785, KAKENHI-PROJECT-26462611
[Journal Article] 頭頸部癌に対する姑息的照射治療2015
- Author(s)
  上原貴行，真栄田裕行，山下懐，長谷川昌宏，安慶名信也，鈴木幹男
- Journal Title
  
  耳鼻咽喉科臨床
  
  Volume: 108 Pages: 475-481
- NAID
  130005072171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462610
[Journal Article] Effects of Methylation Status of CpG Sites within the HPV16 Long Control Region on HPV16-Positive Head and Neck Cancer Cells.2015
- Author(s)
  Zhang C, Deng Z, Pan X, Uehara T, Suzuki M, Xie M.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 10 Pages: e0141245-e0141245
- DOI
  10.1371/journal.pone.0141245
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462611
[Journal Article] Epstein-Barr virus and human papillomavirus infections and genotype distribution in head and neck cancers2014
- Author(s)
  Deng, Suzuki et al
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 11 Pages: e113702-e113702
- DOI
  10.1371/journal.pone.0113702
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462610, KAKENHI-PROJECT-26462611
[Journal Article] Galanin Receptor 2 Utilizes Distinct Signaling Pathways to Suppress Cell Proliferation and Induce Apoptosis in HNSCC.2014
- Author(s)
  Kanazawa T, Misawa K, Misawa Y, Maruta M, Uehara T, Kawada K, Nagatomo T, Ichimura K
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592539
[Journal Article] A comprehensive evaluation of human papillomavirus positive status and p16INK4a overexpression as a prognostic biomarker in head and neck squamous cell carcinoma.2014
- Author(s)
  Deng Z, Suzuki M, et al
- Journal Title
  
  Int J Oncol
  
  Volume: 45 Issue: 1 Pages: 67-76
- DOI
  10.3892/ijo.2014.2440
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462610, KAKENHI-PROJECT-26462611
[Journal Article] Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells2014
- Author(s)
  Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey TE, Suzuki M, Ichimura K, Ozawa K
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Pages: 72-80
- Data Source
  KAKENHI-PROJECT-23592539
[Journal Article] Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells.2014
- Author(s)
  Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey TE, Suzuki M, Ichimura K, Ozawa K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592539
[Journal Article] Galanin Receptor 2 Utilizes Distinct Signaling Pathways to Suppress Cell Proliferation and Induce Apoptosis in HNSCC
- Author(s)
  Kanazawa T, Misawa K, Misawa Y, Maruta M, Uehara T, Kawada K, Nagatomo T, Ichimura K
- Journal Title
  
  Mol Med Rep
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23592539
[Presentation] 頭頸部扁平上皮癌におけるガラニン受容体2型を介する新たな抗腫瘍機構の解明2012
- Author(s)
  上原貴行,金澤丈治,水上浩明,内堀亮介,塚原智典,卜部匡司,久米晃啓,三澤清,小澤敬也
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592539
[Presentation] Galanin受容体2型導入による頭頸部癌遺伝子治療研究2012
- Author(s)
  金澤丈治,上原貴行,三澤清,鈴木幹男,市村恵一
- Organizer
  第36回日本頭頸部癌学会総会・学術講演会
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-23592539
[Presentation] アデノ随伴ウイルスベクターを用いたガラニン受容体2型遺伝子導入による抗腫瘍効果の検討2012
- Author(s)
  上原貴行,金澤丈治,市村恵一,鈴木幹男
- Organizer
  第113回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-23592539

1. Suzuki Mikio (00226557)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 真栄田裕行 (40264501)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. Deng Zeyi (50723863)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. KANAZAWA Takeharu (20336374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. ICHIMUR Keiichi (00010471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. MIZUKAMI Hiroaki (20311938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 池上太郎 (00754409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 近藤俊輔 (90596363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HASEGAWA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 山下懐

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Uehara Takayuki 上原 貴行

UEHARA Takayuki 上原 貴行

Research Projects

Research Products

Co-Researchers

Development of novel treatment targeting mTOR pathway Raptor in HPV-related head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Efficacy of novel dendritic cell vaccine treatment for HPV-related cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prediction of primary treatment outcome and prognosis by viral infection and tumor activity in head and neck cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of carcinogenesis mechanism induced by human papillomavirus using DNA methylation as an indicator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new immunotherapy using a dendritic cell in human papilloma virus-related head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preclinical study for Head and Neck Cancer using rAAV-GALR2

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Branchiogenic carcinoma with high-risk-type human papillomavirus infection: A case report2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 【中咽頭癌-HPVの視点からみた大きな変化】 疫学と病態 中咽頭癌と子宮頸癌のHPVの違いは?2016

Author(s)

Journal Title

Data Source

[Journal Article] Squamous cell carcinoma antigen as a diagnositic marker of nasal inverted papilloma2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human papillomavurus infection and immunohisitochemical expression of cell cycle proteins pRb, p53, and p16(INK4a) in sinonasal diseases2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 頭頸部癌に対する姑息的照射治療2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effects of Methylation Status of CpG Sites within the HPV16 Long Control Region on HPV16-Positive Head and Neck Cancer Cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epstein-Barr virus and human papillomavirus infections and genotype distribution in head and neck cancers2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Galanin Receptor 2 Utilizes Distinct Signaling Pathways to Suppress Cell Proliferation and Induce Apoptosis in HNSCC.2014

Author(s)

Journal Title

Data Source

[Journal Article] A comprehensive evaluation of human papillomavirus positive status and p16INK4a overexpression as a prognostic biomarker in head and neck squamous cell carcinoma.2014

Uehara Takayuki 上原貴行

UEHARA Takayuki 上原貴行

[Journal Article] 【中咽頭癌-HPVの視点からみた大きな変化】疫学と病態　中咽頭癌と子宮頸癌のHPVの違いは?2016