horlad hasita 哈斯塔

… Alternative Names

HORLAD Hasita ホラドハシタ

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Researcher Number	00644840
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2019: 熊本大学, 大学院生命科学研究部(医), 研究員 2015: 熊本大学, その他の研究科, 研究員 2014: 熊本大学, 大学院生命科学研究部, 研究員 2013: 熊本大学, 大学院生命科学研究部, 学術研究員
Review Section/Research Field	Principal Investigator Experimental pathology / Human pathology Except Principal Investigator Human pathology / Hematology / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator マクロファージ / 細胞間相互作用 / リンパ腫 / CADM1 / リンパ節 / CD169 Except Principal Investigator CD169 / 乳癌 / 天然化合物 / CD163 … More / マクロファージ / CD204 / がん治療法開発 / がん関連線維芽細胞 / IL-6 / 癌治療法開発 / 担癌モデルマウス / イカリソウ / α1-酸性糖蛋白 / 浸潤性膀胱癌 / リンパ節洞マクロファージ / 新規がん治療法 / CD163欠損マウス / 未分化多形肉腫 / トリプルネガティブ乳癌 / 腫瘍微小環境 / 腫瘍随伴マクロファージ / 治療 / 白血病 / コレステロール / リンパ腫 / 大腸癌 / CXCL10 / 膵癌 / バイオマーカー / 子宮内膜癌 / 食道癌 / 膀胱癌 / CCL8 / 抗腫瘍免疫 / ヒト癌組織 / リンパ洞マクロファージ / スルフィド化合物 / ガン免疫 / 環状スルフィド化合物 / 代替医療 / ガン / マクロファージクロファージ / がん免疫 / がん Less

cell cell interaction with macrophages and lymphomaPrincipal Investigator
- Principal Investigator
  
  horlad hasita
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kumamoto University
Strategic analysis for the development of new anticancer treatments targeting tumor-associated macrophages
- Principal Investigator
  
  Takeya Motohiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kumamoto Health Science University
  Kumamoto University
The significance of macrophages in several diseases
- Principal Investigator
  
  Komohara Yoshihiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kumamoto University
Novel anti-cancer therapy with cyclic sulfide compounds regulating macrophage activation
- Principal Investigator
  
  Fujiwara Yukio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Kumamoto University
Search of the new biomarkers reflecting lymph node macrophage function and its application to molecular pathology
- Principal Investigator
  
  Takeya Motohiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kumamoto University
Anti-lymphoma therapy targeting cholesterol metabolism
- Principal Investigator
  
  Komohara Yoshihiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Does the balance in lymphoma of immunity become the prognostic factor of cancer?Principal Investigator
- Principal Investigator
  
  horlad hasita
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kumamoto University

All 2020 2019 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment2020
- Author(s)
  Pan Cheng、Fujiwara Yukio、Horlad Hasita、Shiraishi Daisuke、Iriki Toyohisa、Tsuboki Jyunko、Ikeda Tsuyoshi、Komohara Yoshihiro
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 11 Pages: 00262-00262
- DOI
  10.3389/fphar.2020.00262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08603, KAKENHI-PROJECT-19K09555, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-17K08763, KAKENHI-PROJECT-20K07122
[Journal Article] CD163 is required for protumoral activation of macrophages in human and murine sarcoma.2018
- Author(s)
  Shiraishi D, Fujiwara Y, Horlad H, Saito Y, Iriki T, Tsuboki J, Pan C, Nakagata N, Mizuta H, Bekki H, Nakashima Y, Oda Y, Takeya M, Komohara Y (**).
- Journal Title
  
  Cancer Res. 78;3255-3266, 2018
  
  Volume: 78 Pages: 3255-3255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] CD163 is required for protumoral activation of macrophages in human and murine sarcoma.2018
- Author(s)
  Shiraishi D, Fujiwara Y, Horlad H, Saito Y, Iriki T, Tsuboki J, Cheng P, Nakagata N, Mizuta H, Bekki H, Nakashima Y, Oda Y, Takeya M, Komohara Y.
- Journal Title
  
  Cancer Res
  
  Volume: in press Issue: 12 Pages: 3255-3266
- DOI
  10.1158/0008-5472.can-17-2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08763, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-18J01441, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K10865, KAKENHI-PROJECT-16K15248
[Journal Article] CD163-positive cancer cells are potentially associated with high malignant potential in clear cell renal cell carcinoma2018
- Author(s)
  Ma Chaoya、Horlad Hasita、Ohnishi Koji、Nakagawa Takenobu、Yamada Sohsuke、Kitada Shohei、Motoshima Takanobu、Kamba Tomomi、Nakayama Toshiyuki、Fujimoto Naohiro、Takeya Motohiro、Komohara Yoshihiro
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 51 Issue: 1 Pages: 13-20
- DOI
  10.1007/s00795-017-0165-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K11013, KAKENHI-PROJECT-16K15248
[Journal Article] CD163-positive cancer cells are potentially associated with high malignant potential in clear cell renal cell carcinoma2018
- Author(s)
  Ma C, Horlad H, Ohnishi K, Nakagawa T, Yamada S, Kitada S, Motoshima T, Kamba T, Nakayama T, Takeya M, Komohara Y (**).
- Journal Title
  
  Med Mol Morphol. 51:13-20, 2018.
  
  Volume: 51 Pages: 13-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] Optimum immunohistochemical procedures for analysis of macrophages in human and mouse formalin fixed paraffin-embedded tissue samples.2017
- Author(s)
  Nakagawa T, Ohnishi K, Kosaki Y, Saito Y, Horlad H, Fujiwara Y, Takeya M, Komohara Y
- Journal Title
  
  J Clin Exp Hematop.
  
  Volume: 57:
- NAID
  130005709518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines2017
- Author(s)
  Ma C, Horlad H, Pan C, Yano H, Ohnishi K, Fujiwara Y, Matsuoka M, Lee A, Niidome T, Yamanaka R, Takeya M, Komohara Y
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 57 Issue: 1 Pages: 21-25
- DOI
  10.3960/jslrt.17006
- NAID
  130005709510
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-17K08763, KAKENHI-PROJECT-16K15248, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-16K15903
[Journal Article] The cell-cell interaction between tumor-associated macrophages and small cell lung cancer cells is involved in tumor progression via STAT3 activation2017
- Author(s)
  Iriki Toyohisa、Ohnishi Koji、Fujiwara Yukio、Horlad Hasita、Saito Yoichi、Pan Cheng、Ikeda Koei、Mori Takeshi、Suzuki Makoto、Ichiyasu Hidenori、Kohrogi Hirotsugu、Takeya Motohiro、Komohara Yoshihiro
- Journal Title
  
  Lung Cancer
  
  Volume: 106 Pages: 22-32
- DOI
  10.1016/j.lungcan.2017.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K15248, KAKENHI-PROJECT-17H04060
[Journal Article] Recent advances in research regarding to natural compounds that target pro-tumor macrophages.2017
- Author(s)
  Komohara Y, Fujiwara Y, Ohnishi K, Horlad H, Saito Y, Takeya M.
- Journal Title
  
  Macrophage
  
  Volume: 4
- DOI
  10.14800/macrophage.1507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15248, KAKENHI-PROJECT-17H04060
[Journal Article] Cell adhesion molecule-1 (CADM1) expressed on adult T-cell leukemia/lymphoma cells is not involved in the interaction with macrophages.2017
- Author(s)
  Komohara Y, Ma C, Yano H, Pan C, Horlad H, Saito Y, Ohnishi K, Fujiwara Y, Okuno Y, Nosaka K, Shimosaki S, Morishita K, Matsuoka M, Wakayama T, Takeya M
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 57 Issue: 1 Pages: 15-20
- DOI
  10.3960/jslrt.17003
- NAID
  130005709559
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-17K08763, KAKENHI-PROJECT-16K15248, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-26461427
[Journal Article] Optimum immunohistochemical procedures for analysis of macrophages in human and mouse formalin fixed paraffin-embedded tissue samples2017
- Author(s)
  Nakagawa T, Ohnishi K, Kosaki Y, Saito Y, Horlad H, Fujiwara Y, Takeya M, Komohara Y
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 57 Issue: 1 Pages: 31-36
- DOI
  10.3960/jslrt.17017
- NAID
  130005709518
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09247
[Journal Article] Cell adhesion molecule-1 (CADM1) expressed on adult T-cell leukemia/lymphoma cells is not involved in the interaction with macrophages2017
- Author(s)
  Komohara Y, Ma, C, Yano H, Pan C, Horlad H, Saito Y, Ohnishi K, Fujiwara Y, Okuno Y, Nosaka K, Shinosaki S, Morishita K, Matsuoka M, Wakayama T, Takeya M.
- Journal Title
  
  J Clin Exp Hematop.
  
  Volume: 57:
- NAID
  130005709559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] High density of CD204-positive macrophages predicts worse clinical prognosis in patients with breast cancer2017
- Author(s)
  Miyasato Y, Shiota T, Ohnishi K, Pan C, Yano H, Horlad H, Yamamoto Y, Yamamoto-Ibusuki M, Iwase H, Takeya M, Komohara Y.
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 8 Pages: 1693-1700
- DOI
  10.1111/cas.13287
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04060
[Journal Article] Selective depletion of cultured macrophages by magnetite nanoparticles modified with gelatin2017
- Author(s)
  Komohara Yoshihiro、Kawauchi Ryuta、Makiyama Erika、Mikami Kazuki、Horlad Hasita、Fujiwara Yukio、Kida Tetsuya、Takeya Motohiro、Niidome Takuro
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 14 Issue: 2 Pages: 1640-1646
- DOI
  10.3892/etm.2017.4640
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09247
[Journal Article] The high density of CD204-positive macrophages predicts worse clinical prognosis in patients with breast cancer.2017
- Author(s)
  Miyasato Y, Shiota T, Ohnishi K, Pan C, Yano H, Horlad H, Yamamoto Y, Yamamoto-Ibusuki M, Iwase H, Takeya M, Komohara Y
- Journal Title
  
  Cancer Sci.
  
  Volume: 108;
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] The cell-cell interaction between tumor-associated macrophages and small cell lung cancer cells is involved in tumor progression via STAT3 activation.2017
- Author(s)
  Iriki T, Ohnishi K, Fujiwara Y, Horlad H, Saito Y, Ikeda K, Mori T, Suzuki M, Ichiyasu H, Kohrogi H, Takeya M, Komohara Y
- Journal Title
  
  Lung Cancer
  
  Volume: 106,
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] TIM-3 expression in lymphoma cells predicts chemoresistance in patients with adult T-cell leukemia/lymphoma (ATLL).2016
- Author(s)
  Horlad H, Ohnishi K, Ma C, Fujiwara Y, Niino D, Ohshima K, Jinushi M, Matsuoka M, Takeya M, Komohara Y
- Journal Title
  
  Oncol Lett 12: 1519-1524, 2016
  
  Volume: 12 Pages: 1519-1524
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] TIM-3 expression in lymphoma cells predicts chemoresistance in patients with adult T-cell leukemia/lymphoma (ATLL).2016
- Author(s)
  Horlad H, Ohnishi K, Ma C, Fujiwara Y, Niino D, Ohshima K, Jinushi M, Matsuoka M, Takeya M, Komohara Y.
- Journal Title
  
  Oncol Lett
  
  Volume: 12 Issue: 2 Pages: 1519-1524
- DOI
  10.3892/ol.2016.4774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460454, KAKENHI-PROJECT-16K09247
[Journal Article] Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages.2016
- Author(s)
  Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, Motohara T, Saito Y, Ikeda T, Takaishi K, Tashiro H, Yonemoto Y, Katabuchi H, Takeya M, Komohara Y.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 29588-29588
- DOI
  10.1038/srep29588
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K10865, KAKENHI-PROJECT-16K11145
[Journal Article] An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma.2016
- Author(s)
  Horlad H, Ma C, Yano H, Pan C, Ohnishi K, Fujiwara Y, Endo S, Kikukawa Y, Okuno Y, Matsuoka M, Takeya M, Komohara Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 11 Pages: 1696-1704
- DOI
  10.1111/cas.13065
- NAID
  120006223644
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K15248
[Journal Article] TIM-3 expression in lymphoma cells predicts chemoresistance in patients with adult T-cell leukemia/lymphoma (ATLL).2016
- Author(s)
  Horlad H, Ohnishi K, Ma C, Fujiwara Y, Niino D, Ohshima K, Jinushi M, Matsuoka M, Takeya M, Komohara Y.
- Journal Title
  
  Oncol Lett
  
  Volume: in press Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460460
[Journal Article] Onionin A, a sulfur-containing compound isolated from onions, impairs tumor development and lung metastasis by inhibiting the protumoral and immunosuppressive functions of myeloid cells.2016
- Author(s)
  Fujiwara Y, Horlad H, Shiraishi D, Tsuboki J, Kudo R, Ikeda T, Nohara T, Takeya M, Komohara Y
- Journal Title
  
  Mol Nutr Food Res 60:2467-2480, 2016.
  
  Volume: 60
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma2016
- Author(s)
  Horlad H, Ma C, Yano H, Pan C, Ohnishi K, Fujiwara Y, Endo S, Kikukawa Y, Okuno Y, Matsuoka M, Takeya M, Komohara Y
- Journal Title
  
  ancer Sci 107:1696-1704, 2016.
  
  Volume: 107 Pages: 1696-1704
- NAID
  120006223644
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] Onionin A, a sulfur-containing compound isolated from onions, impairs tumor development and lung metastasis by inhibiting the protumoral and immunosuppressive functions of myeloid cells2016
- Author(s)
  Fujiwara Yukio, Horlad Hasita, Shiraishi Daisuke, Tsuboki Junko, Kudo Rino, Ikeda Tsuyoshi, Nohara Toshihiro, Takeya Motohiro, Komohara Yoshihiro
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 60(11) Issue: 11 Pages: 2467-2480
- DOI
  10.1002/mnfr.201500995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460141, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K10865
[Journal Article] Prognostic significance of CD169+ lymph node sinus macrophages in patients with malignant melanoma.2015
- Author(s)
  Saito Y, Ohnishi K, Miyashita A, Nakahara S, Fujiwara Y, Horlad H, Motoshima T, Fukushima S, Jinnin M, Ihn H, Takeya M, Komohara Y.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 3 Pages: 1356-1363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460460
[Journal Article] The coordinated actions of TIM-3 on cancer and myeloid cells in the regulation of tumorigenicity and clinical prognosis in clear cell renal cell carcinomas.2015
- Author(s)
  Komohara Y, Morita T, Annan DA, Horlad H, Ohnishi K, Yamada S, Nakayama T, Kitada S, Suzu S, Kinoshita I, Dosaka-Akita H, Akashi K, Takeya M, Jinushi M.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 3 Pages: 999-1007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460460
[Journal Article] Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells2013
- Author(s)
  Horlad Hasita, Fujiwara Yukio, Takemura Kenichi, Ohnishi Koji, Ikeda Tsuyoshi, Tsukamoto Hirotake, Mizuta Hiroshi, Nishimura Yasuharu, Takeya Motohiro, Komohara Yoshihiro
- Journal Title
  
  Mol. Nutri. Food Res
  
  Volume: 57 (6) Issue: 6 Pages: 1-9
- DOI
  10.1002/mnfr.201200610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590010, KAKENHI-PROJECT-23659204, KAKENHI-PROJECT-23790407, KAKENHI-PROJECT-23790747, KAKENHI-PROJECT-24700994, KAKENHI-PROJECT-24790353, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-25460460, KAKENHI-PROJECT-25860501
[Journal Article] Role of Stat3 activation in cell-cell interaction between B-cell lymphoma and macrophages: the in vitro study2013
- Author(s)
  Bai Bing,　 Horlad Hasita
- Journal Title
  
  日本リンパ網内系学会誌
  
  Volume: 53(2) Pages: 127-33
- NAID
  10031194234
- Data Source
  KAKENHI-PROJECT-25460460
[Presentation] The role of CD163-positive macrophages in human and murine sarcoma - a new target for anti-cancer therapy.2019
- Author(s)
  Motohiro Takeya, Daisuke Shiraishi, Yukio Fujiwara, Hasita Horlad, Yoichi Saito, Yoshihiro Komohara
- Organizer
  5th CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] 肉腫の腫瘍微小環境におけるマクロファージスカベンジャー受容体CD163の機能解析2018
- Author(s)
  藤原章雄、白石大偉輔、Hasita Horlad、菰原義弘
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] コレステロール代謝経路を標的とした高悪性度リンパ腫の治療戦略2018
- Author(s)
  潘程、藤原章雄、Horlad Hasita、中川雄伸、宮川育子、菰原義弘
- Organizer
  平成30年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] ヒトマクロファージをターゲットとした創薬研究. ポスター賞（日本ハム賞）2018
- Author(s)
  藤原章雄、西東洋一、Horlad Hasita、菰原義弘
- Organizer
  第7回超異分野学会
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] M2-likeマーカーであるCD163はマクロファージの腫瘍促進性活性化に関与する2018
- Author(s)
  菰原義弘、白石大偉輔、西東洋一、Horlad Hasita、藤原章雄
- Organizer
  第22回日本がん免疫学会総会　2018年8月1日～3日岡山コンペンションセンター　（岡山）
- Data Source
  KAKENHI-PROJECT-16H05162
[Presentation] Targeting cholesterol efflux is a promising approach for anti-lymphoma therapy.2018
- Author(s)
  Cheng Pan, Hasita Horlad, Yukio Fujiwara, Daisuke Niino, Yutaka Okuno, Masao Matsuoka, Motohiro Takeya, Yoshihiro Komohara.
- Organizer
  The 14th Japanese-Korean Lymphoreticular Workshop 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] Targeting cholesterol efflux is a promising approach for anti-lymphoma therapy.2018
- Author(s)
  Cheng Pan, Hasita Horlad, Yukio Fujiwara, Daisuke Niino, Yutaka Okuno, Masao Matsuoka, Motohiro Takeya, Yoshihiro Komohara.
- Organizer
  The 14th Japanese-Korean Lymphoreticular Workshop 2018
- Data Source
  KAKENHI-PROJECT-16K15248
[Presentation] 肉腫の腫瘍微小環境におけるマクロファージスカベンジャー受容体 CD163の機能解析2018
- Author(s)
  藤原章雄、白石大偉輔、Hasita Horlad、菰原義弘
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] Macropahge-regulating compounds inhibit small cell lung cancer proliferation by suppressing the protumour function of macrophages2018
- Author(s)
  Yukio Fujiwara, Toyohisa Iriki, Hasita Horlad, Yoichi Saito, Cheng Pan, Takenobu Nakagawa, Ikuko Miyagawa, Koji Ohnishi, Yoshihiro Komohara
- Organizer
  The 6th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] M2-likeマーカーであるCD163はマクロファージの腫瘍促進性活性化に関与する2018
- Author(s)
  菰原義弘、白石大偉輔、西東洋一、Horlad Hasita、藤原章雄
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K08763
[Presentation] ヒトマクロファージをターゲットとした創薬研究2018
- Author(s)
  藤原章雄、西東洋一、Horlad Hasita、菰原義弘
- Organizer
  第7回超異分野学会
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] M2-likeマーカーであるCD163はマクロファージの腫瘍促進性活性化に関与する2018
- Author(s)
  菰原義弘、白石大偉輔、西東洋一、Horlad Hasita、藤原章雄
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] Onionin A, a sulfur-containing compound isolated from onions, impairs tumor progression by inhibiting the protumoral functions of macrophages.2017
- Author(s)
  Yukio Fujiwara, Junko Tsuboki, Hasita Horlad, Daisuke Shiraishi, Toshihiro Nohara, Yoshihiro Komohara, Motohiro Takeya.
- Organizer
  Keystone Symposia, Mononuclear Phagocytes in Health, Immune Defense and Disease (D3)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] コレステロール代謝を標的としたガンの新たな治療戦略. 優秀ポスター賞受賞2017
- Author(s)
  藤原章雄、Hasita Horlad、Pan Cheng、矢野浩夢、宮川育子、中川雄伸、竹屋元裕、菰原義弘
- Organizer
  第５回がんと代謝研究会 in 札幌
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] タマネギ由来成分Onionin Aはマクロファージの活性化を制御することで腫瘍の進展を抑制する2017
- Author(s)
  藤原章雄、坪木純子、Horlad Hasita、野原稔弘、池田剛、竹屋元裕、菰原義弘
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都、京都女子大学
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] 悪性リンパ腫に対する脂質代謝阻害剤の有用性2017
- Author(s)
  藤原章雄、Horlad Hasita、Pan Cheng、矢野浩夢、西東洋一、宮川育子、中川雄伸、竹屋元裕、菰原義弘
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] コレステロール代謝を標的としたガンの新たな治療戦略2017
- Author(s)
  藤原章雄、Hasita Horlad、Pan Cheng、矢野浩夢、宮川育子、中川雄伸、竹屋元裕、菰原義弘
- Organizer
  第５回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] Onionin A, a sulfur-containing compound isolated from onions, impairs tumor progression by inhibiting the protumoral functions of macrophages2017
- Author(s)
  Yukio Fujiwara, Junko Tsuboki, Hasita Horlad, Daisuke Shiraishi, Toshihiro Nohara, Yoshihiro Komohara, Motohiro Takeya
- Organizer
  Keystone Symposia, Mononuclear Phagocytes in Health, Immune Defense and Disease (D3)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] 悪性リンパ腫ではコレステロール代謝経路が治療標的になりうる.2017
- Author(s)
  Horlad Hasita,藤原章雄、新野大輔、菊川吉高、奥野豊、松岡雅夫、竹屋元裕、菰原義弘
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08763
[Presentation] 脳原発悪性リンパ腫におけるマクロファージ/ミクログリアの役割2017
- Author(s)
  菰原義弘、Horlad Hasita、馬超亜、竹屋元裕
- Organizer
  第58回日本神経病理学会
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] 高悪性度リンパ腫ではコレステロール代謝経路が新たな治療ターゲットとなりうる2017
- Author(s)
  藤原章雄、Hasita HORLAD、潘程、中川雄伸、林田唯、竹屋元裕、菰原義弘
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台、仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] The protumor functions of CD163 on tumor-associated macrophages.2017
- Author(s)
  Yoshihiro Komohara, Yukio Fujiwara, Koji Ohnishi, Hasita Horlad, Motohiro Takeya.
- Organizer
  EACR Conference; Defence is the Best Attack,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] CD163 is involved in the protumour activation of macrophages in human and murine sarcoma.2017
- Author(s)
  Yoshihiro Komohara, Yukio Fujiwara, Hasita Horlad, Yoichi Saito, Koji Ohnishi, Motohiro Takeya.
- Organizer
  Cytokine2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] 悪性リンパ腫に対する脂質代謝阻害剤の有用性2017
- Author(s)
  藤原章雄、Horlad Hasita、Pan Cheng、矢野浩夢、西東洋一、宮川育子、中川雄伸、竹屋元裕、菰原義弘
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] 淡明型腎細胞癌におけるCD163陽性癌細胞の意義2017
- Author(s)
  菰原義弘、馬超亜、Horlad Hasita、大西紘二、竹屋元裕
- Organizer
  第49回日本臨床分子形態学会総会
- Data Source
  KAKENHI-PROJECT-17H04060
[Presentation] PD-L1/2 expressions in tumor associated macrophages are dependent on IL-27/Stat3 signal.2017
- Author(s)
  Hsita Horlad.
- Organizer
  Kumamoto University Advance Research Project A "International Research Center for Cancer and Metabolism"
- Place of Presentation
  Kumamoto University, Kumamoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15248
[Presentation] CD163, a scavenger receptor for the hemoglobin-haptoglobin complex, relates to tumorgenesis in murine sarcoma model.2016
- Author(s)
  Yukio Fujiwara, Daisuke Shiraishi, Hasita Horlad, Hiroshi Mizuta, Yoshihiro Komohara, Motohiro Takeya
- Organizer
  The 24th International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  Tokyo Bay Maihama Hotel Club Resort, Urayasu, Chiba
- Year and Date
  2016-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] Inhibitory Effect on Lymphoma Cells Proliferation by Regulating Cholesterol Metabolism Pathway2016
- Author(s)
  Yukio Fujiwara, Hasita Horlad, Daisuke Niino, Yutaka Okuno, Yoshitaka Kikukawa, Masao Matsuoka, Motohiro Takeya, Yoshihiro Komohara
- Organizer
  The 5th JCA-AACR Special Joint Conference
- Place of Presentation
  (Tokyo Bay Maihama Hotel Club Resort, Urayasu, Chiba
- Year and Date
  2016-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] Inhibitory effect on Lymphoma Cell Proliferation by Regulating Cholesterol Metabolism Pathway2016
- Author(s)
  Yukio Fujiwara, Hasita Horlad, Daisuke Niino, Yutaka Okuno, Kikukawa Yoshitaka, Masao Matsuoka, Motohiro Takeya, Yoshihiro Komohara,
- Organizer
  THE 1ST MEETING OF THE YONGLIN HEALTHCARE SYMPOSIUM SERIES-“DNA PROCESSES, DRUGS AND CANCER”　 2016/11/27-28 National Taiwan University, Taiwan
- Place of Presentation
  台北
- Year and Date
  2016-11-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05162
[Presentation] コレステロール代謝経路を標的とした高悪性度リンパ腫に対する新たな治療戦略2016
- Author(s)
  藤原章雄、Horlad Hasita、菰原義弘、新野大介、奥野豊、菊川佳敬、松岡雅雄、竹屋元裕
- Organizer
  第56回日本リンパ網内系学会総会
- Place of Presentation
  熊本、ホテル日航熊本
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] Infiltrating Macrophages Express PD-L1 and PD-L2 in Lymphoma Microenvironment2016
- Author(s)
  Yoshihiro Komohara, Hasita Horlad, Chaoya Ma, Shinya Endo, Yoshitaka Kikukawa, Yutaka Okuno, Masao Matsuoka, Motohiro Takeya
- Organizer
  THE 1ST MEETING OF THE YONGLIN HEALTHCARE SYMPOSIUM SERIES-“DNA PROCESSES, DRUGS AND CANCER”　 2016/11/27-28 National Taiwan University, Taiwan
- Place of Presentation
  台北
- Year and Date
  2016-11-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05162
[Presentation] Inhibitory effect on Lymphoma Cell Proliferation by Regulating Cholesterol Metabolism Pathway.2016
- Author(s)
  Yukio Fujiwara, Hasita Horlad, Daisuke Niino, Yutaka Okuno, Kikukawa Yoshitaka, Masao Matsuoka, Motohiro Takeya, Yoshihiro Komohara
- Organizer
  THE 1ST MEETING OF THE YONGLIN HEALTHCARE SYMPOSIUM SERIES-“DNA PROCESSES, DRUGS AND CANCER
- Place of Presentation
  National Taiwan University, Taiwan
- Year and Date
  2016-11-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] The clinical relevance and prognostic significance of CD169+ lymph node macrophages in human malignant tumors.2016
- Author(s)
  Koji Ohnishi, Yoichi Saito, Takuya Shiota, Hasita Horlad, Yukio Fujiwara, Motohiro Takeya, Yoshihiro Komohara.
- Organizer
  The 24th International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  Sola City Conference Center, Tokyo
- Year and Date
  2016-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15248
[Presentation] 悪性腫瘍患者におけるCD169陽性リンパ節洞マクロファージの臨床的意義2016
- Author(s)
  大西紘二、西東洋一、塩田拓也、ハスタホルラド、藤原章雄、竹屋元裕、菰原義弘
- Organizer
  第62回日本病理学会総会
- Place of Presentation
  金沢市文化ホール、金沢
- Data Source
  KAKENHI-PROJECT-16K15248
[Presentation] コレステロール排出経路を標的とした新たながん治療戦略2016
- Author(s)
  菰原義弘、藤原章雄、Horlad Hasita 、矢野浩夢、潘程、竹屋元裕
- Organizer
  第48回日本臨床分子形態学会総会
- Place of Presentation
  熊本
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-16K15503
[Presentation] コレステロール排出経路を標的とした新たながん治療戦略2016
- Author(s)
  菰原義弘、藤原章雄、Horlad Hasita 、矢野浩夢、潘程、竹屋元裕
- Organizer
  第48回日本臨床分子形態学会総会　2016年9月23日～24日（くまもと県民交流会館パレア、熊本）
- Place of Presentation
  熊本
- Year and Date
  2016-09-23
- Invited
- Data Source
  KAKENHI-PROJECT-16H05162
[Presentation] 脂質代謝制御によるリンパ腫に対する新たな治療戦略2016
- Author(s)
  藤原章雄、Horlad Hasita、新野大介、奥野豊、菊川佳敬、松岡雅雄、竹屋元裕、菰原義弘
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K09247
[Presentation] Inhibitory effect on Lymphoma Cell Proliferation by Regulating Cholesterol Metabolism Pathway2016
- Author(s)
  Yukio Fujiwara, Hasita Horlad, Daisuke Niino, Yutaka Okuno, Kikukawa Yoshitaka, Masao Matsuoka, Motohiro Takeya, Yoshihiro Komohara,
- Organizer
  THE 1ST MEETING OF THE YONGLIN HEALTHCARE SYMPOSIUM SERIES-“DNA PROCESSES, DRUGS AND CANCER”
- Place of Presentation
  台湾
- Year and Date
  2016-11-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15503
[Presentation] TIM3 expression in lymphoma cells is involved in chemo-resistance in patients with adult T-cell leukemia/lymphoma (ATLL).2015
- Author(s)
  Horlad Hasita, Yoshihiro Komohara, Daisuke Niino, Koichi Ohshima, Motohiro Takeya.
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋、名古屋国際会議場
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-25460460
[Presentation] マクロファージ由来C5aはStat3の活性化を介してB細胞リンパ腫の増殖を促進する2013
- Author(s)
  Horlad Hasita, 白氷、菰原義弘、竹屋元裕.
- Organizer
  第53回　日本リンパ網内系学会総会
- Place of Presentation
  京都　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25460460
[Presentation] M2マクロファージ由来のC5aはB細胞リンパ腫の増殖を促進する2013
- Author(s)
  Horlad Hasita、菰原義弘、竹屋元裕
- Organizer
  第10回日本病理学会カンファレンス2013六甲山
- Place of Presentation
  神戸、六甲山ホテル
- Data Source
  KAKENHI-PROJECT-25460460

1. Komohara Yoshihiro (40449921)

# of Collaborated Projects: 6 results

# of Collaborated Products: 46 results
2. Fujiwara Yukio (70452886)

# of Collaborated Projects: 5 results

# of Collaborated Products: 45 results
3. 大西紘二 (40613378)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
4. Takeya Motohiro (90155052)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
5. 浅野謙一 (10513400)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Matsuoka Masao (10244138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Okuno Yutaka (80363539)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 白石大偉輔 (70769512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 西東洋一 (20783567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 池田剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 入來豊久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

horlad hasita 哈 斯塔

HORLAD Hasita ホラド ハシタ

Research Projects

Research Products

Co-Researchers

cell cell interaction with macrophages and lymphomaPrincipal Investigator

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Strategic analysis for the development of new anticancer treatments targeting tumor-associated macrophages

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The significance of macrophages in several diseases

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Novel anti-cancer therapy with cyclic sulfide compounds regulating macrophage activation

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Search of the new biomarkers reflecting lymph node macrophage function and its application to molecular pathology

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Anti-lymphoma therapy targeting cholesterol metabolism

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Does the balance in lymphoma of immunity become the prognostic factor of cancer?Principal Investigator

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[Journal Article] Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment2020

Author(s)

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DOI

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[Journal Article] CD163 is required for protumoral activation of macrophages in human and murine sarcoma.2018

Author(s)

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Data Source

[Journal Article] CD163 is required for protumoral activation of macrophages in human and murine sarcoma.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD163-positive cancer cells are potentially associated with high malignant potential in clear cell renal cell carcinoma2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD163-positive cancer cells are potentially associated with high malignant potential in clear cell renal cell carcinoma2018

Author(s)

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[Journal Article] Optimum immunohistochemical procedures for analysis of macrophages in human and mouse formalin fixed paraffin-embedded tissue samples.2017

Author(s)

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NAID

Data Source

[Journal Article] Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines2017

Author(s)

Journal Title

DOI

NAID

horlad hasita 哈斯塔

HORLAD Hasita ホラドハシタ