Hashimoto Takashi 端本宇志

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HASHIMOTO Takashi 端本宇志

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Researcher Number	00647844
Other IDs	https://orcid.org/0000-0001-6779-5598
Affiliation (Current)	2024: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 皮膚科学, 准教授
Affiliation (based on the past Project Information) *help	2022: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 皮膚科学, 准教授 2019 – 2021: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院皮膚科, 講師 2017 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2015: 東京医科歯科大学, 大学院医歯学総合研究科・皮膚科学分野, 助教 2013 – 2015: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 助教
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator マクロファージ / アトピー性皮膚炎 / 好塩基球 / 痒疹 / 痒み / かゆみ / STAT3 / 末梢神経 / IL-31 / 皮膚アレルギー疾患 … More / 免疫学 / アレルギー・ぜんそく / 慢性皮膚炎 / 皮膚慢性炎症 / アレルギー / アンフィレグリン / ペリオスチン / TSLP / そう痒 / M2マクロファージ / モデルマウス / Th2 / STAT6 / IgE / 皮膚アレルギー … More Except Principal Investigator ERK / TSLP / 痒み / 好酸球 / そう痒 / STAT6 / 好塩基球 / 痒疹 Less

アトピー性皮膚炎の痒み過敏発生機序の解明：IL-31と好塩基球による末梢神経変容Principal Investigator
- Principal Investigator
  
  端本宇志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  National Defense Medical College
Mechanisms of itch in atopic dermatitis and prurigo: role of IL-31 from macrophagesPrincipal Investigator
- Principal Investigator
  
  Hashimoto Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  National Defense Medical College
Mechanisms of prurigo: role of amphifegulin and STAT3Principal Investigator
- Principal Investigator
  
  Hashimoto Takashi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical and Dental University
痒疹モデルマウスの樹立と解析による治療方法の研究Principal Investigator
- Principal Investigator
  
  端本宇志
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  National Defense Medical College
Analysis of immunological mechanisms and therapeutic approach for prurigo, itch, and other pruritic skin diseases
- Principal Investigator
  
  Satoh Takahiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  National Defense Medical College

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 苦手な外来皮膚疾患１００の解決法～慢性痒疹治療の決め手2014
- Author(s)
  端本宇志，佐藤貴浩
- Total Pages
  248
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25860978
[Journal Article] IL-31?generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin2023
- Author(s)
  Hashimoto Takashi、Yokozeki Hiroo、Karasuyama Hajime、Satoh Takahiro
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 151 Issue: 3 Pages: 737-746.e6
- DOI
  10.1016/j.jaci.2022.11.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08395, KAKENHI-PROJECT-21K18255, KAKENHI-PROJECT-23K24107
[Journal Article] Increased sensitivity to touch‐evoked itch (punctate hyperknesis) in prurigo nodularis and type 2 inflammation: A cross‐sectional pilot study2023
- Author(s)
  Hashimoto Takashi、Okuno Satoshi、Okuzawa Manami、Satoh Takahiro
- Journal Title
  
  Journal of the European Academy of Dermatology and Venereology
  
  Volume: － Issue: 6
- DOI
  10.1111/jdv.18942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08395
[Journal Article] Dupilumab improves both histaminergic and touch‐evoked itch sensitization (hyperknesis) in atopic dermatitis: a pilot study2022
- Author(s)
  Hashimoto T.、Okuno S.、Okuzawa M.、Satoh T.
- Journal Title
  
  Journal of the European Academy of Dermatology and Venereology
  
  Volume: 36 Issue: 11
- DOI
  10.1111/jdv.18356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08395, KAKENHI-PROJECT-22K08444
[Journal Article] Increased touch‐evoked itch (punctate hyperknesis) in postherpetic itch: Implications of reduced intraepidermal nerve fibers representing small fiber neuropathy2022
- Author(s)
  Hashimoto Takashi、Okuzawa Manami、Yamamoto Mihiro、Okuno Satoshi、Satoh Takahiro
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 50 Issue: 3 Pages: 393-396
- DOI
  10.1111/1346-8138.16627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08395
[Journal Article] Eruptive pruritic papular porokeratosis accompanied by eosinophilic and basophilic infiltrate with upregulation of epidermal CCL26/eotaxin‐3 and thymic stromal lymphopoietin2021
- Author(s)
  Awatani Kayo、Hashimoto Takashi、Satoh Takahiro
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 48 Issue: 8
- DOI
  10.1111/1346-8138.15949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] Periostin, an Emerging Player in Itch Sensation2021
- Author(s)
  Hashimoto Takashi、Mishra Santosh K.、Olivry Thierry、Yosipovitch Gil
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 141 Issue: 10 Pages: 2338-2343
- DOI
  10.1016/j.jid.2021.03.009
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] Linear porokeratosis with severe itch accompanied by lesional upregulation of interleukin 31, thymic stromal lymphopoietin, and periostin2021
- Author(s)
  Hashimoto Takashi、Moriyama Yoshihiro、Satoh Takahiro
- Journal Title
  
  European Journal of Dermatology
  
  Volume: 31 Issue: 4 Pages: 570-572
- DOI
  10.1684/ejd.2021.4083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08743, KAKENHI-PROJECT-19K08805
[Journal Article] Itch intensity in prurigo nodularis is closely related to dermal interleukin‐31, oncostatin M, IL‐31 receptor alpha and oncostatin M receptor beta2021
- Author(s)
  Hashimoto Takashi、Nattkemper Leigh A.、Kim Hei Sung、Kursewicz Christina D.、Fowler Emilie、Shah Serena M.、Nanda Sonali、Fayne Rachel A.、Paolini John F.、Romanelli Paolo、Yosipovitch Gil
- Journal Title
  
  Experimental Dermatology
  
  Volume: - Issue: 6 Pages: 804-810
- DOI
  10.1111/exd.14279
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] Dermal Periostin: A New Player in Itch of Prurigo Nodularis2021
- Author(s)
  Hashimoto T、Nattkemper L、Kim H、Kursewicz C、Fowler E、Shah S、Nanda S、Fayne R、Romanelli P、Yosipovitch G
- Journal Title
  
  Acta Dermato Venereologica
  
  Volume: 101 Issue: 1 Pages: adv00375-adv00375
- DOI
  10.2340/00015555-3702
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages2020
- Author(s)
  Hashimoto Takashi、Kursewicz Christina Dorothy、Fayne Rachel Alison、Nanda Sonali、Shah Serena Maya、Nattkemper Leigh、Yokozeki Hiroo、Yosipovitch Gil
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 140 Issue: 4 Pages: 850-859.e3
- DOI
  10.1016/j.jid.2019.09.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] Itchy body: Topographical difference of itch and scratching and C Nerve fibres2019
- Author(s)
  Hashimoto Takashi、Yosipovitch Gil
- Journal Title
  
  Experimental Dermatology
  
  Volume: 28 Issue: 12 Pages: 1385-1389
- DOI
  10.1111/exd.14054
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] 【痒疹って、何?】 (Part4)痒疹の治療　こんなときのコツ(治療8)　こんなときSSRI/SNRIが効く(解説/特集)2019
- Author(s)
  端本宇志
- Journal Title
  
  Visual Dermatology
  
  Volume: 18 Pages: 207-209
- Data Source
  KAKENHI-PROJECT-17K16328
[Journal Article] Pruritus in ordinary scabies: IL-31 from macrophages induced by overexpression of TSLP and periostin2019
- Author(s)
  Hashimoto Takashi、Satoh Takahiro、Yokozeki Hiroo
- Journal Title
  
  Allergy
  
  Volume: 印刷中 Issue: 9 Pages: 1727-1737
- DOI
  10.1111/all.13870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16328, KAKENHI-PROJECT-19K08743, KAKENHI-PROJECT-19K08805
[Journal Article] Possible roles of basophils in chronic itch2019
- Author(s)
  Hashimoto Takashi、Rosen Jordan D.、Sanders Kristen M.、Yosipovitch Gil
- Journal Title
  
  Experimental Dermatology
  
  Volume: 28 Issue: 12 Pages: 1373-1379
- DOI
  10.1111/exd.13705
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] Amphiregulin from basophils amplifies basophil-mediated chronic skin inflammation2019
- Author(s)
  Hashimoto Takashi、Satoh Takahiro、Karasuyama Hajime、Yokozeki Hiroo
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: - Issue: 8 Pages: 1834-837
- DOI
  10.1016/j.jid.2019.02.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-17K16328, KAKENHI-PROJECT-19K08805, KAKENHI-PROJECT-19H01025
[Journal Article] Itching for an answer: A review of potential mechanisms of scalp itch in psoriasis2019
- Author(s)
  Leon Argentina、Rosen Jordan D.、Hashimoto Takashi、Fostini Anna C.、Paus Ralf、Yosipovitch Gil
- Journal Title
  
  Experimental Dermatology
  
  Volume: 28 Issue: 12 Pages: 1397-1404
- DOI
  10.1111/exd.13947
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] 【痒疹って、何?】 (Part1)基本的な痒疹(総説3)　痒疹はなぜ痒い?(総説/特集)2019
- Author(s)
  端本宇志
- Journal Title
  
  Visual Dermatology
  
  Volume: 18 Pages: 151-155
- Data Source
  KAKENHI-PROJECT-17K16328
[Journal Article] Itching as a systemic disease2019
- Author(s)
  Hashimoto Takashi、Yosipovitch Gil
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 144 Issue: 2 Pages: 375-380
- DOI
  10.1016/j.jaci.2019.04.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Journal Article] Prurigo successfully treated with duloxetine hydrochloride.2018
- Author(s)
  Hashimoto T, Satoh T, Yokozeki H.
- Journal Title
  
  Australas J Dermatol.
  
  Volume: 印刷中 Issue: 3 Pages: 237-239
- DOI
  10.1111/ajd.12996
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10124, KAKENHI-PROJECT-17K16328, KAKENHI-PROJECT-19K08743, KAKENHI-PROJECT-19K08805
[Journal Article] アトピー性皮膚炎の病態に基づいた新たなアプローチ　痒疹モデルからみた治療戦略2016
- Author(s)
  端本宇志、佐藤貴浩
- Journal Title
  
  アレルギー・免疫
  
  Volume: 2月号
- Data Source
  KAKENHI-PROJECT-25860978
[Journal Article] Fish collagen allergy: a pitfall of the prick-to-prick test with raw fish.2015
- Author(s)
  Chikazawa S, Hashimoto T, Kobayashi Y, Satoh T.
- Journal Title
  
  Br J Dermatol
  
  Volume: 173 Issue: 5 Pages: 1330-1331
- DOI
  10.1111/bjd.13962
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461719
[Journal Article] 特集 mast cell が関与する皮膚疾患ー皮膚科医にとっての must Part.2 肥満細胞:皮膚疾患における役割結節性痒疹2015
- Author(s)
  端本宇志，佐藤貴浩
- Journal Title
  
  Visual Dermatology
  
  Volume: 14 Pages: 74-75
- Data Source
  KAKENHI-PROJECT-25860978
[Journal Article] Protective Role of STAT6 in Basophil-Dependent Prurigo-like Allergic Skin Inflammation.2015
- Author(s)
  Hashimoto T, Satoh T, Yokozeki H
- Journal Title
  
  The journal of immunology
  
  Volume: 未定 Issue: 10 Pages: 4631-40
- DOI
  10.4049/jimmunol.1401032
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860978, KAKENHI-PROJECT-25461665, KAKENHI-PROJECT-25461719
[Journal Article] 痒疹はどのようにしてできるのか～動物のデータから～2015
- Author(s)
  端本宇志、佐藤貴浩
- Journal Title
  
  皮膚アレルギーフロンティア
  
  Volume: 13 Pages: 27-30
- Data Source
  KAKENHI-PROJECT-25860978
[Journal Article] Generalized pruritus in parimary sclerosing cholangitis- implications of histamine by lysophosphatidic acid.2015
- Author(s)
  Hashimoto T, Satoh T.
- Journal Title
  
  Br J Dermatol
  
  Volume: 173 Issue: 5 Pages: 1334-1336
- DOI
  10.1111/bjd.13992
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461719
[Journal Article] Eosinophilic pustular folliculitis clinically presenting as orofacial granuloma: successful treatment with indomethacin, but not ibuprofen.2015
- Author(s)
  Ono K, Hashimoto T, Satoh T.
- Journal Title
  
  Acta Derm venereal
  
  Volume: 95 Issue: 3 Pages: 361-362
- DOI
  10.2340/00015555-1926
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461719
[Journal Article] Kimura’s disease with prurigo lesions treated with systemic indomethacin.2014
- Author(s)
  Hashimoto T, Satoh T, Furuya A, Kataoka N, Yokozeki H.
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: ２８ Issue: 9 Pages: 1260-1262
- DOI
  10.1111/jdv.12339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461719, KAKENHI-PROJECT-25860978
[Journal Article] IgG/IgA pemphigus recognizing desmogleins 1 and 3 in a patient with Sjögren’s syndrome.2014
- Author(s)
  Furuya A, Takahashi E, Ishii N, Hashimoto T, Satoh T
- Journal Title
  
  Eur J Dermatol
  
  Volume: ２４ Pages: 512-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461719
[Presentation] デュピクセントはアトピー性皮膚炎患者の痒み過敏を改善する2022
- Author(s)
  端本宇志、奥野聡、奥澤愛美、佐藤貴浩
- Organizer
  第71回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-22K08395
[Presentation] Itch sensitization (punctate hyperknesis) in prurigo nodularis and postherpetic itch: implications of reduced intraepidermal nerve fibers2022
- Author(s)
  Hashimoto T, Okuno S, Okuzawa M, Satoh T
- Organizer
  The 47th Annual Meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-22K08395
[Presentation] 痒疹の痒み　痒み発生機序の最新の知見と対処法2021
- Author(s)
  端本宇志
- Organizer
  第120回日本皮膚科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08743
[Presentation] IL-31, a major pruritogen in a mouse model of atopic dermatitis, is generated through the macrophage/TSLP/periostin axis.2021
- Author(s)
  Hashimoto T, Satoh T.
- Organizer
  The 46th Annual Meeting of the JSID.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Presentation] SY1-2アトピー性皮膚炎の痒み2021
- Author(s)
  端本宇志
- Organizer
  第85回日本皮膚科学会東京支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08743
[Presentation] Macrophages are the major cellular sources of IL-31 in atopic dermatitis:a novel network of itch comprising TSLP, periostin, and basophils2020
- Author(s)
  Takashi Hashimoto, Hiroo Yokozeki, Takahiro Satoh
- Organizer
  45th Japanese Society for Investigative Dermatology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Presentation] Implications of dermal IL-31 from M2 macrophages in itch in murine models of atopic dermatitis2020
- Author(s)
  Takashi Hashimoto, Takahiro Satoh
- Organizer
  JSA/WAO Joint Congress in 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Presentation] Mechanisms of itch in stasis dermatitis: Significant role of IL-31 from macrophages.2019
- Author(s)
  Takashi Hashimoto, Christina Dorothy Kursewicz, Rachel Alison Fayne, Sonali Nanda, Serena Maya Shah,
- Organizer
  10th World Congress of Itch
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Presentation] Overexpression of dermal IL-31 generated by M2 macrophages and itch in murine models of atopic dermatitis2019
- Author(s)
  Takashi Hashimoto, Takahiro Satoh, Hiroo Yokozeki
- Organizer
  10th World Congress of Itch
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08743
[Presentation] Pruritus in ordinary scabies: its immunological responses and IL-31 from macrophages under overexpression of TSLP and periostin2018
- Author(s)
  Hashimoto Takashi、Satoh Takahiro、Yokozeki Hiroo
- Organizer
  International Investigative Dermatology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16328
[Presentation] Basophils release amphiregulin and may contribute to murine models of prurigo reaction and MC903-induced atopic dermatitis-like skin inflammation.2017
- Author(s)
  Hashimoto T, Satoh T, Yokozeki H
- Organizer
  76th annual meeting of SID
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16328
[Presentation] Generalized pruritus provoked by lysophosphatidic acid-induced histamine in a patient with primary sclerosing cholangitis.2015
- Author(s)
  Hashimoto T, Satoh T
- Organizer
  8th World Congress of Itch
- Place of Presentation
  Ｎａｒａ
- Year and Date
  2015-09-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461719
[Presentation] 好塩基球とIgEにより誘発されるマウス痒疹反応におけるそう痒と病変部表皮内神経伸長2014
- Author(s)
  端本宇志，佐藤貴浩，横関博雄
- Organizer
  第26回日本アレルギー学会春季臨床大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25860978
[Presentation] “広義”多形慢性痒疹の臨床的検討2013
- Author(s)
  端本宇志，佐藤貴浩，横関博雄
- Organizer
  第43回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-25860978
[Presentation] nhibition of STAT6 signals exacerbates IgE- mediated, basophil- dependent prurigo-like reactions.2013
- Author(s)
  Hashimoto T, Satoh T, Yokozeki H
- Organizer
  International investigative dermatology 2013
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-25860978
[Presentation] Inhibition of STAT6 signals exacerbates IgE-mediated, basophil-dependent prurigo-like reactions.
- Author(s)
  Hashimoto T, Satoh T, Yokozeki H
- Organizer
  Internatinal Investigative Dermatology 2013
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-25461719
[Presentation] Reciprocal functions of STAT3 and STAT6 signals in basophil-dependent prurigo-like reactions
- Author(s)
  Hashimoto T, Satoh T, Yokozeki H.
- Organizer
  the 39th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  大阪
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25860978

1. Satoh Takahiro (30235361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. FURUYA Aiko (30622972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. YOKOZEKI Hiroo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 烏山一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Takashi 端本 宇志

HASHIMOTO Takashi 端本 宇志

Research Projects

Research Products

Co-Researchers

アトピー性皮膚炎の痒み過敏発生機序の解明：IL-31と好塩基球による末梢神経変容Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of itch in atopic dermatitis and prurigo: role of IL-31 from macrophagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of prurigo: role of amphifegulin and STAT3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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痒疹モデルマウスの樹立と解析による治療方法の研究Principal Investigator

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Analysis of immunological mechanisms and therapeutic approach for prurigo, itch, and other pruritic skin diseases

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[Book] 苦手な外来皮膚疾患１００の解決法～慢性痒疹治療の決め手2014

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[Journal Article] IL-31?generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin2023

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[Journal Article] Increased sensitivity to touch‐evoked itch (punctate hyperknesis) in prurigo nodularis and type 2 inflammation: A cross‐sectional pilot study2023

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[Journal Article] Dupilumab improves both histaminergic and touch‐evoked itch sensitization (hyperknesis) in atopic dermatitis: a pilot study2022

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[Journal Article] Increased touch‐evoked itch (punctate hyperknesis) in postherpetic itch: Implications of reduced intraepidermal nerve fibers representing small fiber neuropathy2022

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[Journal Article] Eruptive pruritic papular porokeratosis accompanied by eosinophilic and basophilic infiltrate with upregulation of epidermal CCL26/eotaxin‐3 and thymic stromal lymphopoietin2021

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[Journal Article] Periostin, an Emerging Player in Itch Sensation2021

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[Journal Article] Linear porokeratosis with severe itch accompanied by lesional upregulation of interleukin 31, thymic stromal lymphopoietin, and periostin2021

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[Journal Article] Itch intensity in prurigo nodularis is closely related to dermal interleukin‐31, oncostatin M, IL‐31 receptor alpha and oncostatin M receptor beta2021

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Hashimoto Takashi 端本宇志

HASHIMOTO Takashi 端本宇志

[Journal Article] 【痒疹って、何?】 (Part4)痒疹の治療　こんなときのコツ(治療8)　こんなときSSRI/SNRIが効く(解説/特集)2019

[Journal Article] 【痒疹って、何?】 (Part1)基本的な痒疹(総説3)　痒疹はなぜ痒い?(総説/特集)2019

[Journal Article] アトピー性皮膚炎の病態に基づいた新たなアプローチ　痒疹モデルからみた治療戦略2016

[Journal Article] 特集 mast cell が関与する皮膚疾患ー皮膚科医にとっての must Part.2 肥満細胞:皮膚疾患における役割結節性痒疹2015