Takei Gen L. 竹井元

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竹井元タケイゲン

Takei Gen 竹井元

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Researcher Number	00708183
Other IDs
Affiliation (Current)	2025: 獨協医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 獨協医科大学, 医学部, 講師 2023: 獨協医科大学, 医学部, 講師 2021 – 2022: 獨協医科大学, 医学部, 助教 2015 – 2018: 獨協医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / General physiology
Keywords	Principal Investigator 受精能獲得 / 精巣上体 / 抗酸化 / ヒポタウリン / 男性不妊 / チオール基 / 受精 / 精子 / 過酸化水素 / 活性酸素種 … More / NKA / NCX / Na+/K+ ATPase / Na+/Ca2+ exchanger / 鞭毛運動 / Na Ca Exchanger / Na-Ca Exchanger / Na/K ATPase / Na+ / 超活性化 / 哺乳類精子 … More Except Principal Investigator 低温 / 低力学負荷 / 心不全 / 低力学負荷環境 / ラット / T管膜 / 心筋細胞 / ハムスター / 冬眠 / ＭＲＩ / 赤外プレチスモグラフィー / MRI / ビデオマイクロスコピー / ムラサキイガイ / 鰓線毛 / 線毛運動 / 水頭症 / 脳脊髄液 Less

ヒポタウリンによる射精前精子の保護機構の解明～生殖補助医療への応用を見据えてPrincipal Investigator
- Principal Investigator
  
  竹井元
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Dokkyo Medical University
Study on the T-tubule System in Hibernating Mammals (Hamsters) for the Development of Innovative Heart Failure Prevention Methods
- Principal Investigator
  
  Ujihara Yoshihiro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Nagoya Institute of Technology
How hydrogen peroxide regulate fertilization?: The elucidation of the target protein of hydrogen peroxide during fertilization.Principal Investigator
- Principal Investigator
  
  竹井元
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Dokkyo Medical University
Can cilia of ventricular ependymal cells control flow of CSF?
- Principal Investigator
  
  SEO Yoshiteru
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Dokkyo Medical University
Elucidation of regulatory mechanism of capacitation by extracellular Na+ in hamster spermatozoaPrincipal Investigator
- Principal Investigator
  
  Takei Gen
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Dokkyo Medical University

All 2023 2022 2021 2017 2016 2015

All Journal Article Presentation

[Journal Article] Hamster Sperm Possess Functional Na+/Ca2+-Exchanger 1: Its Implication in Hyperactivation2023
- Author(s)
  Takei Gen L.、Ogura Yuhei、Ujihara Yoshihiro、Toyama Fubito、Hayashi Keitaro、Fujita Tomoe
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 10 Pages: 8905-8905
- DOI
  10.3390/ijms24108905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K09378, KAKENHI-PROJECT-22K19934, KAKENHI-PROJECT-23K21852
[Journal Article] Regulation of sperm hyperactivation by transporters involved in Na<sup>+</sup> homeostasis2022
- Author(s)
  L. Takei Gen
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 157 Issue: 3 Pages: 176-180
- DOI
  10.1254/fpj.21110
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-21K09378
[Journal Article] Activation of cAMP‐dependent phosphorylation pathways is independent of ROS production during mouse sperm capacitation2021
- Author(s)
  Gen L. Takei, Darya A. Tourzani, Bidur Paudel, Pablo E. Visconti
- Journal Title
  
  Molecular Reproduction & Development
  
  Volume: 88 Issue: 8 Pages: 544-557
- DOI
  10.1002/mrd.23524
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09378
[Journal Article] γ-Aminobutyric acid suppresses enhancement of hamster sperm hyperactivation by 5-hydroxytryptamine2017
- Author(s)
  Masakatsu Fujinoki and Gen L. Takei
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 63 Issue: 1 Pages: 67-74
- DOI
  10.1262/jrd.2016-091
- NAID
  130005332289
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21323
[Journal Article] Regulatory mechanisms of sperm flagellar motility by metachronal and synchronous sliding of doublet microtubules2017
- Author(s)
  Gen L Takei, Masakatsu Fujinoki, Kaoru Yoshida and Sumio Ishijima
- Journal Title
  
  Molecular Human Reproduction
  
  Volume: 23巻 Issue: 12 Pages: 817-826
- DOI
  10.1093/molehr/gax055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21323
[Journal Article] Regulation of hamster sperm hyperactivation by extracellular Na+.2016
- Author(s)
  Gen L. Takei and Masakatsu Fujinoki
- Journal Title
  
  Reproduction
  
  Volume: 151 Issue: 6 Pages: 589-603
- DOI
  10.1530/rep-15-0367
- NAID
  130007024169
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21323
[Journal Article] Non-genomic regulation and disruption of spermatozoal in vitro hyperactivation by oviductal hormones2016
- Author(s)
  Masakatsu Fujinoki, Gen L. Takei and Hiroe Kon
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 66 Issue: 3 Pages: 207-212
- DOI
  10.1007/s12576-015-0419-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21323
[Journal Article] Regulation of salmonid fish sperm motility by osmotic shock-induced water influx across the plasma membrane2015
- Author(s)
  Takei GL, Mukai C and Okuno M
- Journal Title
  
  Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
  
  Volume: 182 Pages: 84-92
- DOI
  10.1016/j.cbpa.2014.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21323
[Journal Article] Estrogen suppresses melatonin-enhanced hyperactivation of hamster spermatozoa2015
- Author(s)
  Fujinoki M and Takei GL
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 61 Issue: 4 Pages: 287-295
- DOI
  10.1262/jrd.2014-116
- NAID
  130005094653
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] タウリントランスポーター (TauT) を介したヒポタウリンの取り込みによるハムスター精子の抗酸化機構2023
- Author(s)
  竹井元、堀端康博、外山史、林啓太朗、森田亜須可、大内基司、藤田朋恵
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K09378
[Presentation] TauTを介したヒポタウリンによるハムスター精子保護機構2023
- Author(s)
  竹井元、堀端康博、外山史、林啓太朗、森田亜須可、大内基司、藤田朋恵
- Organizer
  第116回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-21K09378
[Presentation] ハムスター精子はTauTを介してヒポタウリンを取り込むことで自身を保護する2023
- Author(s)
  竹井元、堀端康博、外山史、林啓太朗、森田亜須可、大内基司、藤田朋恵
- Organizer
  日本動物学会第94回山形大会
- Data Source
  KAKENHI-PROJECT-21K09378
[Presentation] ハムスター精子は機能的な NCX1 を保持する。2022
- Author(s)
  竹井　元，小椋　悠平，氏原　嘉洋, 外山　史, 林　啓太朗, 藤田　朋恵
- Organizer
  第115回日本繁殖生物学会東京大会
- Data Source
  KAKENHI-PROJECT-21K09378
[Presentation] NCX1がハムスター精子の超活性化運動を制御する2022
- Author(s)
  竹井　元，小椋　悠平，氏原　嘉洋，外山　史，林　啓太朗，藤田　朋恵
- Organizer
  第96回日本薬理学会年会 / 第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19934
[Presentation] Na+/Ca2+ exchanger type 1 functions as a “brake” of hyperactivation in hamster sperm.2022
- Author(s)
  竹井　元，小椋　悠平，氏原　嘉洋, 外山　史, 林　啓太朗, 藤田　朋恵
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K09378
[Presentation] Na+/Ca2+ Exchanger 1によるハムスター精子の超活性化調節2022
- Author(s)
  竹井　元，小椋　悠平，氏原　嘉洋, 外山　史, 林　啓太朗, 藤田　朋恵
- Organizer
  日本動物学会第93回早稲田大会
- Data Source
  KAKENHI-PROJECT-21K09378
[Presentation] ハムスター精子受精能獲得に膜電位の過分極は必要ない2017
- Author(s)
  竹井元　今弘枝
- Organizer
  日本動物学会第88回富山大会
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] Na+/K+ ATPase α4 subunit plays the important role in hyperactivation while α1 subunit is essential for the maintenance of motility in hamster sperm.2017
- Author(s)
  Gen L. Takei and Masakatsu Fujinoki
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] -closed meeting-2017
- Author(s)
  Gen L. Takei
- Organizer
  Gordon Research Conference Fertilization & Activation of Development,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] Na+ K+ ATPaseによる超活性化調節2017
- Author(s)
  竹井元　藤ノ木政勝
- Organizer
  日本アンドロロジー学会第36回学術大会および第25回精子形成・精巣毒性研究会共同開催学会
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] ハムスター精子においてNa+/K+ ATPase α1は生存を、α4は超活性化をそれぞれ調節する2017
- Author(s)
  竹井　元、藤ノ木　政勝
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松　(静岡県浜松市)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] 細胞外ナトリウムによるチロシンリン酸化非依存的なハムスター精子超活性化調節2016
- Author(s)
  竹井　元、藤ノ木　政勝
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] 細胞外ナトリウムによるハムスター精子超活性化調節2016
- Author(s)
  竹井　元、藤ノ木　政勝
- Organizer
  第109回日本繁殖生物学会大会
- Place of Presentation
  麻布大学　(神奈川県相模原市)
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] Regulation of Hamster Sperm Hyperactivation by Na+ via an Action of Na+/Ca2+ Exchanger2016
- Author(s)
  Gen L. Takei and Masakatsu Fujinoki
- Organizer
  12th International Congress of Cell Biology
- Place of Presentation
  Prague Congress Centre (チェコ、プラハ)
- Year and Date
  2016-07-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] 細胞外ナトリウムによる鞭毛運動、及び超活性化の調節2016
- Author(s)
  竹井　元、藤ノ木　政勝
- Organizer
  生体運動研究合同班会議2016
- Place of Presentation
  キャンパスプラザ京都
- Year and Date
  2016-01-08
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] 細胞外ナトリウムによるハムスター精子鞭毛運動調節2016
- Author(s)
  竹井　元、藤ノ木　政勝
- Organizer
  日本アンドロロジー学会第35回学術大会
- Place of Presentation
  前橋テルサ　(群馬県前橋市)
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] 細胞外Na+によるチロシンリン酸化を介さないハムスター精子超活性化調節2015
- Author(s)
  竹井　元、藤ノ木　政勝
- Organizer
  日本動物学会第86回新潟大会
- Place of Presentation
  朱鷺メッセ
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K21323
[Presentation] 細胞外ナトリウムによるハムスター精子超活性化調節機構の解明2015
- Author(s)
  竹井　元、藤ノ木　政勝
- Organizer
  第34回日本アンドロロジー学会学術大会および第22回精子形成・精巣毒性研究会
- Place of Presentation
  福岡大学病院メディカルホール
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K21323

1. SEO Yoshiteru (90179317)

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2. Ujihara Yoshihiro (80610021)

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3. 毛利聡 (00294413)

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4. 中村匡徳 (20448046)

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5. 杉田修啓 (20532104)

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6. 西辻光希 (60770823)

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7. 花島章 (70572981)

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8. 伊藤愛 (00963464)

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9. 堀端康博 (80392116)

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10. 相澤直樹 (80595257)

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11. NAKAHARI takashi

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12. WAKASHIN hidefumi

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13. SEO eriko

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14. HAYASHI Keitaro

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Takei Gen L. 竹井 元

竹井 元 タケイ ゲン

Takei Gen 竹井 元

Research Projects

Research Products

Co-Researchers

ヒポタウリンによる射精前精子の保護機構の解明～生殖補助医療への応用を見据えてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the T-tubule System in Hibernating Mammals (Hamsters) for the Development of Innovative Heart Failure Prevention Methods

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

How hydrogen peroxide regulate fertilization?: The elucidation of the target protein of hydrogen peroxide during fertilization.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Can cilia of ventricular ependymal cells control flow of CSF?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of regulatory mechanism of capacitation by extracellular Na+ in hamster spermatozoaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hamster Sperm Possess Functional Na+/Ca2+-Exchanger 1: Its Implication in Hyperactivation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of sperm hyperactivation by transporters involved in Na<sup>+</sup> homeostasis2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Activation of cAMP‐dependent phosphorylation pathways is independent of ROS production during mouse sperm capacitation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] γ-Aminobutyric acid suppresses enhancement of hamster sperm hyperactivation by 5-hydroxytryptamine2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Regulatory mechanisms of sperm flagellar motility by metachronal and synchronous sliding of doublet microtubules2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of hamster sperm hyperactivation by extracellular Na+.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Non-genomic regulation and disruption of spermatozoal in vitro hyperactivation by oviductal hormones2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of salmonid fish sperm motility by osmotic shock-induced water influx across the plasma membrane2015

Author(s)

Journal Title

Takei Gen L. 竹井元

竹井元タケイゲン

Takei Gen 竹井元