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Takei Gen L.  竹井 元

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竹井 元  タケイ ゲン

Takei Gen  竹井 元

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Researcher Number 00708183
Other IDs
Affiliation (Current) 2025: 獨協医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2025: 獨協医科大学, 医学部, 講師
2023: 獨協医科大学, 医学部, 講師
2021 – 2022: 獨協医科大学, 医学部, 助教
2015 – 2018: 獨協医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56030:Urology-related / Urology
Except Principal Investigator
Medium-sized Section 90:Biomedical engineering and related fields / General physiology
Keywords
Principal Investigator
受精能獲得 / チオール基 / 受精 / 精子 / 過酸化水素 / 活性酸素種 / NKA / NCX / Na+/K+ ATPase / Na+/Ca2+ exchanger … More / 鞭毛運動 / Na Ca Exchanger / Na-Ca Exchanger / Na/K ATPase / Na+ / 超活性化 / 哺乳類精子 … More
Except Principal Investigator
低温 / 低力学負荷 / 心不全 / 低力学負荷環境 / ラット / T管膜 / 心筋細胞 / ハムスター / 冬眠 / MRI / 赤外プレチスモグラフィー / MRI / ビデオマイクロスコピー / ムラサキイガイ / 鰓線毛 / 線毛運動 / 水頭症 / 脳脊髄液 Less
  • Research Projects

    (5 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (12 People)
  •  ヒポタウリンによる射精前精子の保護機構の解明~生殖補助医療への応用を見据えてPrincipal Investigator

    • Principal Investigator
      竹井 元
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Dokkyo Medical University
  •  Study on the T-tubule System in Hibernating Mammals (Hamsters) for the Development of Innovative Heart Failure Prevention Methods

    • Principal Investigator
      Ujihara Yoshihiro
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nagoya Institute of Technology
  •  How hydrogen peroxide regulate fertilization?: The elucidation of the target protein of hydrogen peroxide during fertilization.Principal Investigator

    • Principal Investigator
      竹井 元
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Dokkyo Medical University
  •  Can cilia of ventricular ependymal cells control flow of CSF?

    • Principal Investigator
      SEO Yoshiteru
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Dokkyo Medical University
  •  Elucidation of regulatory mechanism of capacitation by extracellular Na+ in hamster spermatozoaPrincipal Investigator

    • Principal Investigator
      Takei Gen
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Dokkyo Medical University

All 2023 2022 2021 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Hamster Sperm Possess Functional Na+/Ca2+-Exchanger 1: Its Implication in Hyperactivation2023

    • Author(s)
      Takei Gen L.、Ogura Yuhei、Ujihara Yoshihiro、Toyama Fubito、Hayashi Keitaro、Fujita Tomoe
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 10 Pages: 8905-8905

    • DOI

      10.3390/ijms24108905

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K09378, KAKENHI-PROJECT-22K19934, KAKENHI-PROJECT-23K21852
  • [Journal Article] Regulation of sperm hyperactivation by transporters involved in Na<sup>+</sup> homeostasis2022

    • Author(s)
      L. Takei Gen
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 157 Issue: 3 Pages: 176-180

    • DOI

      10.1254/fpj.21110

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Journal Article] Activation of cAMP‐dependent phosphorylation pathways is independent of ROS production during mouse sperm capacitation2021

    • Author(s)
      Gen L. Takei, Darya A. Tourzani, Bidur Paudel, Pablo E. Visconti
    • Journal Title

      Molecular Reproduction & Development

      Volume: 88 Issue: 8 Pages: 544-557

    • DOI

      10.1002/mrd.23524

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Journal Article] γ-Aminobutyric acid suppresses enhancement of hamster sperm hyperactivation by 5-hydroxytryptamine2017

    • Author(s)
      Masakatsu Fujinoki and Gen L. Takei
    • Journal Title

      J. Reprod. Dev.

      Volume: 63 Issue: 1 Pages: 67-74

    • DOI

      10.1262/jrd.2016-091

    • NAID

      130005332289

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Journal Article] Regulatory mechanisms of sperm flagellar motility by metachronal and synchronous sliding of doublet microtubules2017

    • Author(s)
      Gen L Takei, Masakatsu Fujinoki, Kaoru Yoshida and Sumio Ishijima
    • Journal Title

      Molecular Human Reproduction

      Volume: 23巻 Issue: 12 Pages: 817-826

    • DOI

      10.1093/molehr/gax055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Journal Article] Regulation of hamster sperm hyperactivation by extracellular Na+.2016

    • Author(s)
      Gen L. Takei and Masakatsu Fujinoki
    • Journal Title

      Reproduction

      Volume: 151 Issue: 6 Pages: 589-603

    • DOI

      10.1530/rep-15-0367

    • NAID

      130007024169

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Journal Article] Non-genomic regulation and disruption of spermatozoal in vitro hyperactivation by oviductal hormones2016

    • Author(s)
      Masakatsu Fujinoki, Gen L. Takei and Hiroe Kon
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 66 Issue: 3 Pages: 207-212

    • DOI

      10.1007/s12576-015-0419-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Journal Article] Regulation of salmonid fish sperm motility by osmotic shock-induced water influx across the plasma membrane2015

    • Author(s)
      Takei GL, Mukai C and Okuno M
    • Journal Title

      Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

      Volume: 182 Pages: 84-92

    • DOI

      10.1016/j.cbpa.2014.12.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Journal Article] Estrogen suppresses melatonin-enhanced hyperactivation of hamster spermatozoa2015

    • Author(s)
      Fujinoki M and Takei GL
    • Journal Title

      J. Reprod. Dev.

      Volume: 61 Issue: 4 Pages: 287-295

    • DOI

      10.1262/jrd.2014-116

    • NAID

      130005094653

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] タウリントランスポーター (TauT) を介したヒポタウリンの取り込みによるハムスター精子の抗酸化機構2023

    • Author(s)
      竹井元、堀端康博、外山史、林啓太朗、森田亜須可、大内基司、藤田朋恵
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Presentation] TauTを介したヒポタウリンによるハムスター精子保護機構2023

    • Author(s)
      竹井元、堀端康博、外山史、林啓太朗、森田亜須可、大内基司、藤田朋恵
    • Organizer
      第116回日本繁殖生物学会大会
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Presentation] ハムスター精子はTauTを介してヒポタウリンを取り込むことで自身を保護する2023

    • Author(s)
      竹井元、堀端康博、外山史、林啓太朗、森田亜須可、大内基司、藤田朋恵
    • Organizer
      日本動物学会第94回山形大会
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Presentation] ハムスター精子は機能的な NCX1 を保持する。2022

    • Author(s)
      竹井 元,小椋 悠平,氏原 嘉洋, 外山 史, 林 啓太朗, 藤田 朋恵
    • Organizer
      第115回日本繁殖生物学会東京大会
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Presentation] NCX1がハムスター精子の超活性化運動を制御する2022

    • Author(s)
      竹井 元,小椋 悠平,氏原 嘉洋,外山 史,林 啓太朗,藤田 朋恵
    • Organizer
      第96回日本薬理学会年会 / 第43回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19934
  • [Presentation] Na+/Ca2+ exchanger type 1 functions as a “brake” of hyperactivation in hamster sperm.2022

    • Author(s)
      竹井 元,小椋 悠平,氏原 嘉洋, 外山 史, 林 啓太朗, 藤田 朋恵
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Presentation] Na+/Ca2+ Exchanger 1によるハムスター精子の超活性化調節2022

    • Author(s)
      竹井 元,小椋 悠平,氏原 嘉洋, 外山 史, 林 啓太朗, 藤田 朋恵
    • Organizer
      日本動物学会 第93回 早稲田大会
    • Data Source
      KAKENHI-PROJECT-21K09378
  • [Presentation] ハムスター精子受精能獲得に膜電位の過分極は必要ない2017

    • Author(s)
      竹井元 今弘枝
    • Organizer
      日本動物学会第88回富山大会
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] Na+/K+ ATPase α4 subunit plays the important role in hyperactivation while α1 subunit is essential for the maintenance of motility in hamster sperm.2017

    • Author(s)
      Gen L. Takei and Masakatsu Fujinoki
    • Organizer
      4th World Congress of Reproductive Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] -closed meeting-2017

    • Author(s)
      Gen L. Takei
    • Organizer
      Gordon Research Conference Fertilization & Activation of Development,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] Na+ K+ ATPaseによる超活性化調節2017

    • Author(s)
      竹井元 藤ノ木政勝
    • Organizer
      日本アンドロロジー学会第36回学術大会および第25回精子形成・精巣毒性研究会共同開催学会
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] ハムスター精子においてNa+/K+ ATPase α1は生存を、α4は超活性化をそれぞれ調節する2017

    • Author(s)
      竹井 元、藤ノ木 政勝
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松 (静岡県浜松市)
    • Year and Date
      2017-03-28
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] 細胞外ナトリウムによるチロシンリン酸化非依存的なハムスター精子超活性化調節2016

    • Author(s)
      竹井 元、藤ノ木 政勝
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] 細胞外ナトリウムによるハムスター精子超活性化調節2016

    • Author(s)
      竹井 元、藤ノ木 政勝
    • Organizer
      第109回日本繁殖生物学会大会
    • Place of Presentation
      麻布大学 (神奈川県相模原市)
    • Year and Date
      2016-09-12
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] Regulation of Hamster Sperm Hyperactivation by Na+ via an Action of Na+/Ca2+ Exchanger2016

    • Author(s)
      Gen L. Takei and Masakatsu Fujinoki
    • Organizer
      12th International Congress of Cell Biology
    • Place of Presentation
      Prague Congress Centre (チェコ、プラハ)
    • Year and Date
      2016-07-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] 細胞外ナトリウムによる鞭毛運動、及び超活性化の調節2016

    • Author(s)
      竹井 元、藤ノ木 政勝
    • Organizer
      生体運動研究合同班会議2016
    • Place of Presentation
      キャンパスプラザ京都
    • Year and Date
      2016-01-08
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] 細胞外ナトリウムによるハムスター精子鞭毛運動調節2016

    • Author(s)
      竹井 元、藤ノ木 政勝
    • Organizer
      日本アンドロロジー学会第35回学術大会
    • Place of Presentation
      前橋テルサ (群馬県前橋市)
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] 細胞外Na+によるチロシンリン酸化を介さないハムスター精子超活性化調節2015

    • Author(s)
      竹井 元、藤ノ木 政勝
    • Organizer
      日本動物学会第86回新潟大会
    • Place of Presentation
      朱鷺メッセ
    • Year and Date
      2015-09-17
    • Data Source
      KAKENHI-PROJECT-15K21323
  • [Presentation] 細胞外ナトリウムによるハムスター精子超活性化調節機構の解明2015

    • Author(s)
      竹井 元、藤ノ木 政勝
    • Organizer
      第34回日本アンドロロジー学会学術大会および第22回精子形成・精巣毒性研究会
    • Place of Presentation
      福岡大学病院メディカルホール
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K21323
  • 1.  SEO Yoshiteru (90179317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  Ujihara Yoshihiro (80610021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  毛利 聡 (00294413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  中村 匡徳 (20448046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  杉田 修啓 (20532104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  西辻 光希 (60770823)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  花島 章 (70572981)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  伊藤 愛 (00963464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NAKAHARI takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  WAKASHIN hidefumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SEO eriko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HAYASHI Keitaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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