Uehara Osamu 植原治

… Alternative Names

UEHARA Osamu 植原治

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Researcher Number	00709248
Other IDs	https://orcid.org/0000-0001-5602-4448
Affiliation (Current)	2024: 北海道医療大学, 歯学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 北海道医療大学, 歯学部, 講師 2014 – 2020: 北海道医療大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57080:Social dentistry-related / Social dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Basic Section 57030:Conservative dentistry-related / Conservative dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 52010:General internal medicine-related / Social dentistry / Surgical dentistry / Pathobiological dentistry/Dental radiology
Keywords	Principal Investigator エピジェネティクス / マイクロバイオーム / DNAメチル化解析 / 細菌叢解析 / 口腔の老化 / エイジングクロック / RRBS / ぶどう膜炎 / パスウェー解析 / P. gingivalis … More / RNA-seq / 歯周病原細菌 / ベーチェット病 / 慢性腎臓病 / 膵炎 / 歯周炎 / 歯周病 / 膵臓 … More Except Principal Investigator エピジェネティクス / エストロゲン / プロゲステロン / 歯周病治療 / 口腔がん / エクソソーム / 歯根膜 / 歯髄 / マイクロバイオーム / 加齢 / ストレス / RNAシークエンス解析 / RNA-Seq / Microbiome解析 / 女性ホルモン / NAFLD / NASH / HNF4 alpha / MASH / MASLD / エゾウコギ / フィトケミカル / 脂肪肝 / DNAメチル化剤 / DNA脱メチル化剤 / エピゲノム / 膵臓 / 歯周病原菌 / 口腔内細菌叢 / 新生児 / 消化管細菌叢 / 切迫早産 / 妊婦 / メタゲノム解析 / 次世代シーケンス / 口腔細菌叢 / 唾液 / 口腔内アフタ性潰瘍 / ベーチェット病 / 噛みタバコ / SIRT1 / アレコリン / betel quid / 海馬 / 口腔内病原菌内毒素 / S. mutans / キサントフモール / ホップ / 再石灰化 / ヒストン脱アセチル化酵素阻害剤 / 修復組織形成 / 歯髄保存療法剤 Less

加齢における慢性ストレスでの口腔環境の網羅的解析
- Principal Investigator
  
  安彦善裕
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
歯髄細胞の歯根膜細胞への分化誘導に関わるエクソソームの網羅的解析
- Principal Investigator
  
  吉田光希
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Health Sciences University of Hokkaido
フィトケミカル含有食品エゾウコギによる、新しいNAFLD/NASH治療法の開発
- Principal Investigator
  
  河野豊
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokushima
女性の歯周疾患に対するMicrobiome・RNA-Seq診断と治療戦略
- Principal Investigator
  
  加藤幸紀
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
エピジェネティクスおよび細菌叢解析に基づくOral Aging Clockの開発Principal Investigator
- Principal Investigator
  
  植原治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Comprehensive analysis of epigenomic aberrant genes in oral cancer and verification of tumor suppressive effect by epigenomic drugs.
- Principal Investigator
  
  NAGAYASU Hiroki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Epigenetic alterations of pancreas induced by oral bacterial endotoxin
- Principal Investigator
  
  ABIKO Yoshihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Metagenomic analysis of mothers and newborns to determine periodontal treatment strategies for the development of healthy gastrointestinal microflora.
- Principal Investigator
  
  KATO Satsuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Elucidation of the onset mechanism of autoimmune uveitis caused by endotoxin derived from periodontopathic bacteriaPrincipal Investigator
- Principal Investigator
  
  UEHARA Osamu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Genome-wide analysis of epigenetic modification in hippocampus by oral pathogen endotoxin
- Principal Investigator
  
  ABIKO Yoshihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Health Sciences University of Hokkaido
Elucidation of the carcinogenic mechanism for the prevention of oral cancer caused by betel quid chewing
- Principal Investigator
  
  NAGAYASU Hiroki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Health Sciences University of Hokkaido
Metagenomic approach in the investigation of oral microbial communities associated with the Behcet's desease
- Principal Investigator
  
  FUJITA Mari
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Health Sciences University of Hokkaido
Development of hop beverages to control dental plaque
- Principal Investigator
  
  ODACHI Tatsuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Health Sciences University of Hokkaido
Comprehensive epigenetic analysis on pancreas by periodontal pathogenic bacteriaPrincipal Investigator
- Principal Investigator
  
  UEHARA Osamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Social dentistry
- Research Institution
  Health Sciences University of Hokkaido
Establishment of dental pulp preservation therapy using histone deacetylase inhibitor
- Principal Investigator
  
  Kawakami Tomofumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Health Sciences University of Hokkaido

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 Other

All Journal Article Presentation

[Journal Article] Acanthopanax senticosus ameliorates steatohepatitis through HNF4 alpha pathway activation in mice2024
- Author(s)
  Kawano Yutaka、Tanaka Maki、Satoh Yasushi、Sugino Shigekazu、Suzuki Jun、Fujishima Masaki、Okumura Eri、Takekoshi Hideo、Uehara Osamu、Sugita Shintaro、Abiko Yoshihiro、Tomonari Tetsu、Tanaka Hironori、Takeda Hidekatsu、Takayama Tetsuji
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1
- DOI
  10.1038/s41598-023-50625-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07478
[Journal Article] Ingenuity pathway analysis of gingival epithelial cells stimulated with estradiol and progesterone.2024
- Author(s)
  Nodoka Sugiyama, Osamu Uehara, Yutaka Kawano, Durga Paudel, Tetsuro Morikawa, Norihiro Nakamoto, Satsuki Kato, Tetsuji Takayama, Toshiyuki Nagasawa, Hiroko Miura, Yoshihiro Abiko, Yasushi Furuichi.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 66(1) Issue: 1 Pages: 26-34
- DOI
  10.1016/j.job.2023.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10004
[Journal Article] 卵巣摘出マウスにおけるエストロゲンおよびプロゲステロン投与の口腔細菌叢への影響.2023
- Author(s)
  杉山のどか、中本規裕、森川哲郎、パウデルドゥルガ、植原　治、加藤幸紀、安彦善裕、古市保志.
- Journal Title
  
  北海道医療大学歯学会雑誌
  
  Volume: 42 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10004
[Journal Article] Increase in Bifidobacterium is a characteristic of the difference in the salivary microbiota of pregnant and non-pregnant women.2022
- Author(s)
  Kato S, Nagasawa T, Uehara O, Shimizu S, Sugiyama N, Hasegawa-Nakamura K, Noguchi K, Hatae M, Kakinoki H, Furuichi Y.
- Journal Title
  
  BMC Oral Health.
  
  Volume: 22 Issue: 1 Pages: 260-260
- DOI
  10.1186/s12903-022-02293-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09959, KAKENHI-PROJECT-22K10004, KAKENHI-PROJECT-20K09944
[Journal Article] Gut fora alterations due to lipopolysaccharide derived from Porphyromonas gingivalis2022
- Author(s)
  Sugiyama N, Uehara O, Morikawa T, Paudel D, Ebata K, Hiraki D, Harada F, Yoshida K, Kato S, Nagasawa T, Miura H, Abiko Y, Furuichi Y.
- Journal Title
  
  Odontology
  
  Volume: Mar 25 Issue: 4 Pages: 673-681
- DOI
  10.1007/s10266-022-00703-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10157, KAKENHI-PROJECT-20K09944
[Journal Article] DNA hypermethylation of sirtuin 1 (SIRT1) caused by betal quid chewing　-a possible predictive biomarker for malignant transformation.2020
- Author(s)
  Islam S, Uehara O, Matsuoka H, Kuramitsu Y, Adhikari BR, Hiraki D, Toraya S, Jayawardena A, Saito I, Muthumala M, Nagayasu H, Abiko Y, I Chiba.
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 12 Issue: 1 Pages: 12-12
- DOI
  10.1186/s13148-019-0806-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-17K11916
[Journal Article] クルクミンがアレコリン誘発性マトリックスプロテアーゼに与える影響2019
- Author(s)
  森川哲郎、植原　治、平木大地、虎谷斉子、Puja Neopane、Durga Paudel、原田文也、髙井理衣、吉田光希、永易裕樹、千葉逸朗、安彦善裕
- Journal Title
  
  日本口腔検査学会雑誌
  
  Volume: 11 Pages: 25-30
- NAID
  120006605695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11916
[Journal Article] Effect of systemic administration of lipopolysaccharides derived from Porphyromonas gingivalis on gene expression in mice kidney2018
- Author(s)
  Harada Fumiya、Uehara Osamu、Morikawa Tetsuro、Hiraki Daichi、Onishi Aya、Toraya Seiko、Adhikari Bhoj Raj、Takai Rie、Yoshida Koki、Sato Jun、Nishimura Michiko、Chiba Itsuo、Wu Ching Zong、Abiko Yoshihiro
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 51 Issue: 3 Pages: 156-165
- DOI
  10.1007/s00795-018-0181-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20647
[Journal Article] Upregulated expression of MMP-9 in gingival epithelial cells induced by prolonged stimulation with arecoline2017
- Author(s)
  Uehara Osamu、Takimoto Kousuke、Morikawa Tetsuro、Harada Fumiya、Takai Rie、Adhikari Bhoj Raj、Itatsu Ryoko、Nakamura Tomohisa、Yoshida Koki、Matsuoka Hirofumi、Nagayasu Hiroki、Saito Ichiro、Muthumala Malsantha、Chiba Itsuo、Abiko Yoshihiro
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Issue: 1 Pages: 1186-1192
- DOI
  10.3892/ol.2017.6194
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11916
[Journal Article] DNA hypermethylation of extracellular matrix-related genes in human periodontal fibroblasts induced by stimulation for a prolonged period with lipopolysaccharide derived from P. gingivalis2016
- Author(s)
  Rie Takai, Osamu Uehara, Fumiya Harada, Masafumi Utsunomiya, Takatoshi Chujo, Koki Yoshida, Jun Sato, Michiko Nishimura, Itsuo Chiba, Yoshihiro Abiko
- Journal Title
  
  J Periodontal Research
  
  Volume: 51 Issue: 4 Pages: 508-517
- DOI
  10.1111/jre.12330
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20647, KAKENHI-PROJECT-26305035, KAKENHI-PROJECT-25463223
[Presentation] エストラジオールおよびプロゲステロンで刺激した歯肉上皮細胞のパスウェイ解析.2023
- Author(s)
  杉山のどか，植原　治，中本規裕，加藤幸紀，長澤敏行，安彦善裕，古市保志.
- Organizer
  第66回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10004
[Presentation] 妊婦の口腔内状況と女性ホルモンの関連性について2022
- Author(s)
  杉山のどか、加藤幸紀、植原　治、清水伸太郎、長澤敏行、中村　梢、野口和行、波多江正紀、柿木博成、池田奈美、上塘正人、古市保志
- Organizer
  第65回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10004
[Presentation] P. gingivalisのLPSがマウス腸内細菌に与える影響2021
- Author(s)
  杉山のどか、植原治、江端一馬、加藤幸紀、安彦善裕、長澤敏行、古市保志
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10157
[Presentation] Demethylation effect of 5-Azacytidine on oral squamous cell carcinoma2021
- Author(s)
  Koki Yoshida, Shuhei Takahashi, Fumiya Harada, Dedy Ariwansa, Ariuntsetseg Khurelchuluun, Durga Paudel, Daichi Hiraki, Tetsuro Morikawa, Osamu Uehara, Jun Sato, Yoshihiro Abiko, Hiroki Nagayasu
- Organizer
  第34回日本口腔診断学会、31回日本口腔内科学会合同開催学会
- Data Source
  KAKENHI-PROJECT-21K10121
[Presentation] 口腔扁平上皮癌におけるエピゲノム薬の腫瘍抑制効果の検討2021
- Author(s)
  高橋周平、吉田光希、原田文也、Ariwansa Dedy、Khurelchuluun Ariuntsetseg、Paudel Durga、平木大地、森川哲郎、植原治、佐藤惇、永易裕樹、安彦善裕
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K10121
[Presentation] DNA methylation of sirtuin-1 gene could be a novel biomarker for early prediction of betel quidinduced oral cancer2019
- Author(s)
  Islam Shajedul, Uehara Osamu, Kuramitsu Yasuhiro, Nagayasu Hiroki, Chiba Itsuo
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-17K11916
[Presentation] ベテル噛みの口腔粘膜への影響2019
- Author(s)
  原田文也，植原　治，志茂　剛，安彦善裕，永易裕樹
- Organizer
  第73回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-17K11916
[Presentation] Genome-wide Analysis of Dementia-related Genes in Mouse Hippocampus by P. gingivalis -LPS.2019
- Author(s)
  Morikawa T, Uehara O, Harada F, Hiraki D, Onishi A, Takai R, Yoshida K, Sato J, Nishimura M, Chiba I, Michikawa M, Abiko A.
- Organizer
  IADR 97th General Session and Exhibition
- Data Source
  KAKENHI-PROJECT-17K11681
[Presentation] マウス海馬のP.gingivalis由来LPS投与による遺伝子発現の網羅的解析2018
- Author(s)
  森川哲郎, 植原治, 原田文也, Durga Paudel, 大西綾, 平木大地, Puja Neopane, Bhoj Raj Adhikari, 宇津宮雅史, 吉田光希, 佐藤惇, 西村学子, 安彦善裕
- Organizer
  第28回日本口腔内科学会・第31回日本口腔診断学会
- Data Source
  KAKENHI-PROJECT-17K11681
[Presentation] Genome-wide analysis of the gene related to Alzheimer’s disease in mouse hippocampus stimulated with Lipopolysaccharide derived from P. gingivalis.2017
- Author(s)
  Tetsuro Morikawa, Osamu Uehara, Fumiya Harada, Durga Paudel, Aya Onishi, Daichi Hiraki,Puja Neopane, Bhoj Raj Adhikari, Masafumi Utsunomiya, Koki Yoshida, Jun Sato,Michiko Nishimura and Yoshihiro Abiko
- Organizer
  第65回国際歯科研究学会日本部会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11681
[Presentation] マウスにおける歯周病原菌P. gingivalis由来LPSの投与が膵臓の遺伝子発現に与える影響2017
- Author(s)
  平木大地，植原　治，原田文也，森川哲郎，虎谷斉子，安彦善裕
- Organizer
  日本歯周病学会60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-15K20647
[Presentation] Effects of Administration of LPS Derived From P. gingivalis on Kidney Gene-expression in Mice2017
- Author(s)
  M. Nishimura, F. Harada, O. Uehara, T. Morikawa, R. Takai, K. Yoshida, J. Sato, I. Chiba, Y. Abiko
- Organizer
  IADR 95th General Session and Exhibition
- Place of Presentation
  サンフランシスコ、アメリカ
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20647
[Presentation] 歯周病原菌 P.gingivalis (P.g) 由来 Lipopolysaccharide (LPS)によるマウス海馬の遺伝子発現に与える影響2017
- Author(s)
  森川哲郎，植原治，原田文也，Durga Paudel，大西綾，平木大地，Pujya Neopane，Bhoj Raj Adhikari，宇津宮雅史，吉田光希，佐藤惇，西村学子，安彦善裕
- Organizer
  第27回日本口腔内科学会・第30回日本口腔診断学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11681
[Presentation] Histone Deacetylase Inhibitors Induce Differentiation in Preodontoblasts Cell Line
- Author(s)
  Osamu Uehara, Shamima Sultana, Koki Yoshida, Rie Takai, Fumiya Harada, Masato Saitoh, Tomofumi Kawakami, Takashi Saito, Yoshihiro Abiko, Itsuo Chiba
- Organizer
  IADR 93th General Session and Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26462891

1. ABIKO Yoshihiro (90260819)

# of Collaborated Projects: 10 results

# of Collaborated Products: 10 results
2. 長澤敏行 (90262203)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. 吉田光希 (30453260)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. Kawakami Tomofumi (00169682)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. NAGAYASU Hiroki (90265075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. KATO Satsuki (50281283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. 太田亨 (10223835)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 道川誠 (40270912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 高井理衣 (50781085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 藏滿保宏 (50281811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 原田文也 (30824205)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. ODACHI Tatsuji (60214152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FUJITA Mari (50405669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 斎藤隆史 (40265070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 舞田健夫 (40229282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 齊藤正人 (50337036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 北市伸義 (40431366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 千葉逸朗 (50250460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 古市保志 (80305143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 河野豊 (80398320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 田中真樹 (40207139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 三浦宏子 (10183625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 豊福明 (10258551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. PAUDEL Durga (20910590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 野口和行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 中村利明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 長谷川梢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 蔵満保宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uehara Osamu 植原 治

UEHARA Osamu 植原 治

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エピジェネティクスおよび細菌叢解析に基づくOral Aging Clockの開発Principal Investigator

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Elucidation of the onset mechanism of autoimmune uveitis caused by endotoxin derived from periodontopathic bacteriaPrincipal Investigator

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Comprehensive epigenetic analysis on pancreas by periodontal pathogenic bacteriaPrincipal Investigator

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Uehara Osamu 植原治

UEHARA Osamu 植原治

[Journal Article] DNA hypermethylation of sirtuin 1 (SIRT1) caused by betal quid chewing　-a possible predictive biomarker for malignant transformation.2020