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Hashimoto Ko  橋本 功

ORCIDConnect your ORCID iD *help
Researcher Number 00718497
Other IDs
Affiliation (Current) 2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2023: 東北大学, 医学系研究科, 講師
2018: 東北大学, 医学系研究科, 非常勤講師
2014 – 2017: 東北大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Except Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords
Principal Investigator
変形性関節症 / 網羅的解析 / 遺伝子発現 / アンチエイジング / ミトコンドリア / ミトコンドリア機能改善薬 / サルコペニア / マウス / 関節軟骨保護 / MA-5 … More / ミトコンドリア代謝改善 / ミトコンドリア代謝改善薬 / 遺伝子発現調節 / DNAメチル化 / 関節軟骨 / マイクロアレイ / 軟骨細胞 / 網羅的遺伝子解析 / 軟骨基質破壊 / 転写因子、細胞内伝達物質の網羅的発現解析 / 軟骨組織からの核酸抽出技術の確立 / 転写因子 … More
Except Principal Investigator
ゲノム / 遺伝子解析 / 股関節形成不全 / 胸椎後縦靭帯骨化症 / 脊髄内応力 Less
  • Research Projects

    (7 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (9 People)
  •  胸椎後縦靭帯骨化症による脊髄圧迫障害を脊髄内応力マッピングで可視化・定量化する

    • Principal Investigator
      高橋 康平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tohoku University
  •  Novel mitochondrial function-improving drugs for improving skeletal muscle function and treating sarcopeniaPrincipal Investigator

    • Principal Investigator
      橋本 功
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tohoku University
  •  Exploration of disease susceptibility genes for hip dysplasia using the Japonica Array

    • Principal Investigator
      Chiba Daisuke
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tohoku University
  •  The protective effects of new mitochondrial modulators on onset and progression of osteoarthritisPrincipal Investigator

    • Principal Investigator
      Hashimoto Ko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tohoku University
  •  Elucidation of the causative gene of developmental dysplasia of the hip using Japonica array

    • Principal Investigator
      Chiba Daisuke
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tohoku University
  •  Elucidating mechanisms of cartilage matrix destruction via DNA methylationPrincipal Investigator

    • Principal Investigator
      Hashimoto Ko
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tohoku University
  •  Elucidating the function of promoter DNA methylation status on IL1B gene regulation in human articular chondrocytesPrincipal Investigator

    • Principal Investigator
      Hashimoto Ko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tohoku University

All 2023 2022 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Genome-Wide Association Study and Transcriptome of Japanese Patients with Developmental Dysplasia of the Hip Demonstrates an Association with the Ferroptosis Signaling Pathway2023

    • Author(s)
      Mori Yu、Ueno Kazuko、Chiba Daisuke、Hashimoto Ko、Kawai Yosuke、Baba Kazuyoshi、Tanaka Hidetatsu、Aki Takashi、Ogasawara Masanori、Shibasaki Naoto、Tokunaga Katsushi、Aizawa Toshimi、Nagasaki Masao
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 5 Pages: 5019-5019

    • DOI

      10.3390/ijms24055019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09404
  • [Journal Article] A whole-genome transcriptome analysis of articular chondrocytes in secondary osteoarthritis of the hip2018

    • Author(s)
      Takashi Aki, Ko Hashimoto, Masanori Ogasawara, Eiji Itoi
    • Journal Title

      PLoS One

      Volume: 13 Issue: 6 Pages: e0199734-e0199734

    • DOI

      10.1371/journal.pone.0199734

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10882
  • [Presentation] Mitochonic acid-5 (MA-5)による高齢マウスのサルコペニア抑制効果2022

    • Author(s)
      阿部高久、橋本功、大野木孝嘉、佐藤宏陽、芝﨑真人、阿部高明、相澤俊峰
    • Organizer
      第37回 日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-20K09426
  • [Presentation] 新規化合物 mitochonic acid (MA-5) は運動機能と骨格筋ミトコンドリア機能を向上させる2022

    • Author(s)
      佐藤宏陽、橋本功、大野木孝嘉、阿部高久、芝﨑真人、相澤俊峰
    • Organizer
      第37回 日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-20K09426
  • [Presentation] A microarray analysis of gene expression in secondary osteoarthritis of the hip in Japanese2018

    • Author(s)
      Takashi Aki, Ko Hashimoto, Masanori Ogasawara, Eiji Itoi
    • Organizer
      Orthopedic Research Society 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10882
  • [Presentation] Searching potential transcription factors regulating MMP13 overexpression in human osteoarthritic chondrocytes - A microarray screening -2017

    • Author(s)
      Takashi Aki, Ko Hashimoto, Atsushi Takahashi, Masanori Ogasawara, Eiji Itoi
    • Organizer
      World Congress on Osteoarthritis 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10882
  • [Presentation] Searching potential transcription factors regulating MMP13 overexpression via promoter CpG methylation status in human osteoarthritic chondrocytes: A microarray screening2016

    • Author(s)
      秋貴史、橋本功、高橋敦、小笠原将敬、井樋栄二
    • Organizer
      World Congress on Osteoarthritis 2016
    • Place of Presentation
      オランダ・アムステルダム
    • Year and Date
      2016-03-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26870031
  • 1.  Chiba Daisuke (20649727)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  森 優 (70634541)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  鈴木 健弘 (50396438)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  阿部 高明 (80292209)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  大野木 孝嘉 (70913838)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  高橋 康平 (40623252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  相澤 俊峰 (50282132)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  AKI Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  OGASAWARA Masanori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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