Nanjo Shigeki 南條成輝

Researcher Number	00722555
Other IDs
Affiliation (Current)	2025: 金沢大学, 附属病院, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 金沢大学, 附属病院, 講師 2021 – 2023: 金沢大学, がん進展制御研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 分子標的薬耐性 / EML4-ALK融合遺伝子変異 / 非小細胞肺癌 / 転移促進因子 / 薬剤耐性 / RBM10 / EGFR変異肺がん / Bcl-x / アポトーシス / スプライシング因子 / EGFR変異肺癌 / RBM10遺伝子変異 … More Except Principal Investigator … More 耐性変異 / 次世代シーケンス / 肺癌 / 分子標的薬耐性 / 共存変異 / 分子標的薬 Less

分子標的治療誘導性転移の新規分子機構の解明と予防法の確立Principal Investigator
- Principal Investigator
  
  南條成輝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Study to form a theoretical basis for personalized medicine that stratifies EGFR-mutated lung cancer by co-mutations
- Principal Investigator
  
  矢野聖二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kanazawa University
Functional analysis of coexisting RBM10 mutations in EGFR-mutated lung cancerPrincipal Investigator
- Principal Investigator
  
  Nanjo Shigeki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kanazawa University

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] 最新臨床肺癌学日本臨牀 80巻増刊号8（通巻第1225号）2022
- Author(s)
  南條成輝、矢野聖二
- Total Pages
  6
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-21K15546
[Journal Article] Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR.2024
- Author(s)
  Ishibashi Kojiro、Ichinose Toshiya、Kadokawa Riki、Mizutani Ryo、Iwabuchi Sadahiro、Togi Sumihito、Ura Hiroki、Tange Shoichiro、Shinjo Keiko、Nakayama Jun、Nanjo Shigeki、Niida Yo、Kondo Yutaka、Hashimoto Shinichi、Sahai Erik、Yano Seiji、Nakada Mitsutoshi、Hirata Eishu.
- Journal Title
  
  Developmental Cell
  
  Volume: 59 Issue: 5 Pages: 579-594
- DOI
  10.1016/j.devcel.2024.01.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20598, KAKENHI-PROJECT-23K18235, KAKENHI-PROJECT-23K14560, KAKENHI-PROJECT-19KK0209, KAKENHI-PROJECT-19K07661, KAKENHI-PROJECT-23K06633, KAKENHI-PROJECT-23K27438, KAKENHI-PROJECT-23K27609
[Journal Article] Methylation of Tumor Suppressive miRNAs in Plasma from Patients With Pancreaticobiliary Diseases2022
- Author(s)
  OHTSUBO KOUSHIRO、MIYAKE KUNIO、ARAI SACHIKO、FUKUDA KOJI、SUZUKI CHIAKI、KOTANI HIROSHI、TANIMOTO AZUSA、NISHIYAMA AKIHIRO、NANJO SHIGEKI、YAMASHITA KANAME、TAKEUCHI SHINJI、YANO SEIJI
- Journal Title
  
  Cancer Diagnosis Prognosis
  
  Volume: 2 Issue: 3 Pages: 378-383
- DOI
  10.21873/cdp.10120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15546, KAKENHI-PROJECT-20H03928
[Journal Article] Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer2022
- Author(s)
  Nanjo S, Wu W, Karachaliou N, Blakely C, Suzuki J, Chou Y, Ali S, Kerr L, Olivas V, Shue J, Rotow J, Mayekar M, Haderk F, Chatterjee N, Urisman A, Yeo J, Skanderup A, Tan A, Tam W, Arrieta O, Hosomichi K, Nishiyama A, Yano S, Kirichok Y, Tan D, Rosell R, Okimoto R, Bivona T.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 132 Issue: 13
- DOI
  10.1172/jci145099
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15546, KAKENHI-PUBLICLY-21H00342
[Journal Article] A novel approach for the non-invasive diagnosis of pulmonary nodules using low-depth whole-genome sequencing of cell-free DNA2022
- Author(s)
  Zhang Bin、Liang Han、Liu Weiran、Zhou Xinlan、Qiao Sitan、Li Fuqiang、Tian Pengfei、Li Chenguang、Ma Yuchen、Zhang Hua、Zhang Zhenfa、Nanjo Shigeki、Russo Alessandro、Puig-Butille? Joan Anton、Wu Kui、Wang Changli、Zhao Xin、Yue Dongsheng
- Journal Title
  
  Translational Lung Cancer Research
  
  Volume: 11 Issue: 10 Pages: 2094-2110
- DOI
  10.21037/tlcr-22-647
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] 脳脊髄液腫瘍由来DNA(CSF-tDNA）を用いたEGFR変異肺がん中枢神経系転移における治療最適化2023
- Author(s)
  南條成輝
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] EGFR変異肺癌において併存するRBM10遺伝子変異によるEGFR-TKI耐性～なぜEGFR L858R変異に効きにくいのか～2022
- Author(s)
  南條成輝
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] EGFR 変異肺癌におけるRBM10遺伝子変異共存を通してみえてきた遺伝的な不均一性の克服～共存遺伝子による層別化と個別化治療～2022
- Author(s)
  南條成輝
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] Co-mutation in splicing factor with EGFR mutations limits sensitivity to EGFR-TKIs ～Why are EGFR-TKIs less effective against EGFR L858R?～2022
- Author(s)
  南條成輝
- Organizer
  第63回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer2022
- Author(s)
  Shigeki Nanjo
- Organizer
  第19回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer2021
- Author(s)
  Shigeki Nanjo
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] 転移性EGFR変異肺がんにおいて併存するRBM10遺伝子変異によるEGFR-TKI阻害薬耐性2021
- Author(s)
  南條成輝
- Organizer
  第30回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K15546
[Presentation] Co-mutation in splicing factor with EGFR mutations limits sensitivity to EGFR-TKIs ～Why are EGFR-TKIs less effective against EGFR L858R?～2021
- Author(s)
  Shigeki Nanjo
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15546

1. 矢野聖二 (30294672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 木場隼人 (80967886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 近藤豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nanjo Shigeki 南條 成輝

Research Projects

Research Products

Co-Researchers

分子標的治療誘導性転移の新規分子機構の解明と予防法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study to form a theoretical basis for personalized medicine that stratifies EGFR-mutated lung cancer by co-mutations

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of coexisting RBM10 mutations in EGFR-mutated lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 最新臨床肺癌学 日本臨牀 80巻増刊号8（通巻第1225号）2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Methylation of Tumor Suppressive miRNAs in Plasma from Patients With Pancreaticobiliary Diseases2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel approach for the non-invasive diagnosis of pulmonary nodules using low-depth whole-genome sequencing of cell-free DNA2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] 脳脊髄液腫瘍由来DNA(CSF-tDNA）を用いたEGFR変異肺がん中枢神経系転移における治療最適化2023

Author(s)

Organizer

Data Source

[Presentation] EGFR変異肺癌において併存するRBM10遺伝子変異によるEGFR-TKI耐性～なぜEGFR L858R変異に効きにくいのか～2022

Author(s)

Organizer

Data Source

[Presentation] EGFR 変異肺癌におけるRBM10遺伝子変異共存を通してみえてきた遺伝的な不均一性の克服 ～共存遺伝子による層別化と個別化治療～2022

Author(s)

Organizer

Data Source

[Presentation] Co-mutation in splicing factor with EGFR mutations limits sensitivity to EGFR-TKIs ～Why are EGFR-TKIs less effective against EGFR L858R?～2022

Author(s)

Organizer

Data Source

[Presentation] Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer2022

Author(s)

Organizer

Data Source

[Presentation] Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer2021

Author(s)

Organizer

Data Source

[Presentation] 転移性EGFR変異肺がんにおいて併存するRBM10遺伝子変異によるEGFR-TKI阻害薬耐性2021

Author(s)

Organizer

Data Source

[Presentation] Co-mutation in splicing factor with EGFR mutations limits sensitivity to EGFR-TKIs ～Why are EGFR-TKIs less effective against EGFR L858R?～2021

Author(s)

Organizer

Data Source

Nanjo Shigeki 南條成輝

[Book] 最新臨床肺癌学日本臨牀 80巻増刊号8（通巻第1225号）2022

[Presentation] EGFR 変異肺癌におけるRBM10遺伝子変異共存を通してみえてきた遺伝的な不均一性の克服～共存遺伝子による層別化と個別化治療～2022