Kawamura Mikio 川村幹雄

Researcher Number	00722589
Other IDs
Affiliation (Current)	2025: 三重大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 三重大学, 医学部附属病院, 講師 2020 – 2023: 三重大学, 医学系研究科, 助教 2016 – 2019: 三重大学, 医学系研究科, リサーチアソシエイト 2015: 三重大学, 医学部附属病院, その他 2014 – 2015: 三重大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords	Principal Investigator AI / 術前化学放射線療法 / 直腸癌 / ノンコーディングRNA / 予後予測 / エピゲノム / circular RNA / 腹膜播種 / 胃癌 / サイトカイン … More / micro RNA / DNA methylation / 潰瘍性大腸炎 / 回腸嚢炎 … More Except Principal Investigator 潰瘍性大腸炎 / 大腸癌 / DNAメチル化 / エピゲノム / バイオマーカー / 癌進展 / NETs / 食道癌 / 循環DNA / RNAメチル化 / RNAメチル / 潰瘍性大腸炎症 / メチル化 / 孤発性大腸癌 / ゲノム / microRNA / 癌化 / マイクロRNA Less

放射線照射とDNA修復機能抑制性ウイルスベクター導入による直腸癌免疫賦活療法の開発Principal Investigator
- Principal Investigator
  
  川村幹雄
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
Development and validation of a versatile panel targeting colorectal cancer-specific circulating methylated DNA through comprehensive analysis.
- Principal Investigator
  
  問山裕二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
Neutrophil extracellular traps（NETs）を介した食道癌進展の新たな機序の解明
- Principal Investigator
  
  森本雄貴
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
AIとradiomicsによる直腸癌術前治療の効果予測プログラム開発Principal Investigator
- Principal Investigator
  
  川村幹雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
Development of RNA methylation biomarker in Colorectal Cancer
- Principal Investigator
  
  奥川喜永
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
Development of a minimally invasive ulcerative colitis cancer risk diagnostic method using integrated genomic and epigenomic analysis.
- Principal Investigator
  
  Toiyama Yuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
A Molecular Biological Approach to the Diagnosis and Treatment Planning for Ulcerative Colitis-associated Cancer
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
The mechanistic exploration of epigenetic change as for organ specific metastasis in gastric cancerPrincipal Investigator
- Principal Investigator
  
  Kawamura Mikio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Mie University
Comprehensive analyses of DNA methylation for the development of pouchitis after surgery in patients with ulcerative colitisPrincipal Investigator
- Principal Investigator
  
  Kawamura Mikio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Mie University
DNA methylation biomarkers predict development of UC-associated colorectal neoplasia
- Principal Investigator
  
  Toiyama Yuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Mie University

All 2024 2023 2022 2020 2018 2016 Other

All Journal Article Presentation

[Journal Article] Double inferior vena cava, an uncommon but relevant anatomical anomaly in surgery for lower rectal cancer: a report of two cases2023
- Author(s)
  Kawamura Mikio、Yamashita Shinji、Imaoka Hiroki、Shimura Tadanobu、Kitajima Takahito、Okugawa Yoshinaga、Okita Yoshiki、Ohi Masaki、Toiyama Yuji
- Journal Title
  
  Surgical Case Reports
  
  Volume: 9 Issue: 1
- DOI
  10.1186/s40792-023-01738-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08842
[Journal Article] Promoter methylation levels of microRNA-124 in non-neoplastic rectal mucosa as a potential biomarker for ulcerative colitis-associated colorectal cancer in pediatric-onset patients2023
- Author(s)
  Koike Yuhki、Yin Chengzeng、Sato Yuki、Nagano Yuka、Yamamoto Akira、Kitajima Takahito、Shimura Tadanobu、Kawamura Mikio、Matsushita Kohei、Okugawa Yoshinaga、Amano Keishiro、Okita Yoshiki、Ohi Masaki、Inoue Mikihiro、Uchida Keiichi、Hirayama Masahiro、Toiyama Yuji
- Journal Title
  
  Surgery Today
  
  Volume: 54 Issue: 4 Pages: 347-355
- DOI
  10.1007/s00595-023-02738-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08868, KAKENHI-PROJECT-21K08773
[Journal Article] 潰瘍性大腸炎関連癌の分子生物学的アプローチを用いた診断法2022
- Author(s)
  山本晃、大北喜基、今岡裕基、志村匡信、川村幹雄、問山裕二
- Journal Title
  
  日本大腸肛門病学会雑誌
  
  Volume: 75 Pages: 478-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08774
[Journal Article] A Molecular Biological Approach to the Diagnosis of Ulcerative Colitis-associated Cancer2022
- Author(s)
  Yamamoto Akira、Okita Yoshiki、Imaoka Hiroki、Shimura Tadanobu、Kawamura Mikio、Toiyama Yuji
- Journal Title
  
  Nippon Daicho Komonbyo Gakkai Zasshi
  
  Volume: 75 Issue: 10 Pages: 478-486
- DOI
  10.3862/jcoloproctology.75.478
- ISSN
  0047-1801, 1882-9619
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08773
[Journal Article] Prognostic potential of METTL3 expression in patients with gastric cancer2022
- Author(s)
  Okugawa Yoshinaga、Toiyama Yuji、Yin Chengzeng、Ruiya Ma、Goel Akul、Ichikawa Takashi、Imaoka Hiroki、Kitajima Takahito、Shimura Tadanobu、Kawamura Mikio、Yasuda Hiromi、Fujikawa Hiroyuki、Yokoe Takeshi、Mochiki Ikuyo、Ohi Masaki、Nakatani Kaname
- Journal Title
  
  Oncology Letters
  
  Volume: 25 Issue: 2 Pages: 64-64
- DOI
  10.3892/ol.2022.13651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08868
[Journal Article] The relationship between preoperative T helper cytokines in the ileal mucosa and the pathogenesis of pouchitis2020
- Author(s)
  Kitajima Takahito、Okita Yoshiki、Kawamura Mikio、Kondo Satoru、Toiyama Yuji、Uchida Keiichi、Kusunoki Masato
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 20 Issue: 1 Pages: 277-277
- DOI
  10.1186/s12876-020-01421-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09102, KAKENHI-PROJECT-18K08700
[Journal Article] Colony-stimulating factor-1 and colony-stimulating factor-1 receptor co-expression is associated with disease progression in gastric cancer.2018
- Author(s)
  Okugawa Y, Toiyama Y, Ichikawa T, Kawamura M, Yasuda H, Fujikawa H, Saigusa S, Ohi M, Araki T, Tanaka K, Inoue Y, Tanaka M, Miki C, Kusunoki M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 53 Pages: 737-749
- DOI
  10.3892/ijo.2018.4406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08700, KAKENHI-PROJECT-16K10497
[Presentation] 小児発症潰瘍性大腸炎患者における直腸粘膜microRNA-124メチル化レベルと大腸癌発症リスクに関しての検討2024
- Author(s)
  川村幹雄, 今岡裕基, 大北喜基, 小池勇樹, 横田一樹, 松下航平, 長野由佳, 佐藤友紀, 東浩輝, 山下真司, 志村匡信, 北嶋貴仁, 奥川喜永, 吉山繁幸, 大井正貴, 問山裕二
- Organizer
  第98回大腸癌研究会学術集会
- Data Source
  KAKENHI-PROJECT-21K08773
[Presentation] 術前治療後の下部直腸癌に対するロボット支援下直腸切除術の手術成績とトラブルシューティング2023
- Author(s)
  川村幹雄、家城英治、山下真司、志村匡信、北嶋貴仁、今岡裕基、奥川喜永、大北喜基、大井正貴、問山裕二
- Organizer
  第78回　日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08842
[Presentation] T2,T3下部直腸癌に対するTotal neoadjuvant therapyによる臓器温存の試み2023
- Author(s)
  川村幹雄、家城英治、山下真司、志村匡信、北嶋貴仁、今岡裕基、奥川喜永、大北喜基、大井正貴、問山裕二
- Organizer
  第99回　大腸癌研究会
- Data Source
  KAKENHI-PROJECT-22K08842
[Presentation] Optimization of total neoadjuvant therapy to realize a safe and reliable watch and wait approach.2023
- Author(s)
  川村幹雄、家城英治、山下真司、志村匡信、北嶋貴仁、今岡裕基、奥川喜永、大北喜基、大井正貴、問山裕二
- Organizer
  第78回　日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-22K08842
[Presentation] Optimization of total neoadjuvant therapy for lower advanced rectal cancer.2023
- Author(s)
  川村幹雄、大北喜基、問山裕二
- Organizer
  第21回　日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-22K08842
[Presentation] 下部直腸癌に対する術前化学放射線療法による局所制御効果の検討2022
- Author(s)
  川村幹雄
- Organizer
  第122回　日本外科学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08842
[Presentation] 下部進行直腸癌に対する術前治療後の効果判定 -clinical complete response診断能向上を目指した多角的画像評価と再評価の重要性について-2022
- Author(s)
  川村幹雄
- Organizer
  第97回　大腸癌研究会
- Data Source
  KAKENHI-PROJECT-22K08842
[Presentation] DNAメチル化解析を用いた潰瘍性大腸炎関連癌と散発性大腸癌の鑑別法2022
- Author(s)
  大北喜基, 山本晃, 大村悠介, 今岡裕基, 志村匡信, 北嶋貴仁, 川村幹雄, 松下航平, 小池勇樹, 安田裕美, 森本雄貴, 奥川喜永, 横江毅, 大井正貴, 内田恵一, 問山裕二
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08773
[Presentation] DNAメチル化解析を用いた潰瘍性大腸炎関連癌と散発性大腸癌の鑑別法2022
- Author(s)
  大北喜基, 山本晃, 大村悠介, 今岡裕基, 志村匡信, 北嶋貴仁, 川村幹雄, 松下航平, 小池勇樹, 安田裕美, 森本雄貴, 奥川喜永, 横江毅, 大井正貴, 内田恵一, 問山裕二
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08773
[Presentation] 潰瘍性大腸炎術後回腸嚢炎発症と大腸全摘時回腸粘膜中Interferon-γの発現との関連性2016
- Author(s)
  川村幹雄
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪府・大阪市)
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K10136
[Presentation] 大腸全摘時回腸粘膜におけるTh1,Th2,Th17 cytokine profileと回腸嚢炎発症の関連性2016
- Author(s)
  川村幹雄
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル(東京都・新宿区)
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K10136
[Presentation] IBD合併癌(Colitic Cancer)のサーベイランスと治療定量的メチル化解析による潰瘍性大腸炎癌化危険群推定の可能性
- Author(s)
  荒木俊光, 問山裕二, 奥川喜永, 大北喜基, 川村幹雄, 田中光司, 井上靖彦, 毛利靖彦, 楠正人
- Organizer
  日本大腸肛門病学会
- Place of Presentation
  横浜　（横浜ベイホテル東急・パシフィコ横浜）
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26462011
[Presentation] MicroRNA-124プロモーター領域メチル化の大腸癌バイオマーカーとしての可能性
- Author(s)
  問山裕二, Hur Keun, 川村幹雄, 川本文, 奥川喜永, 廣純一郎, 田中光司, 井上靖浩, 永坂岳志, 毛利靖彦, 楠正人, Boland Richard C., Goel Ajay
- Organizer
  日本外科学会
- Place of Presentation
  京都　（国立京都国際会館・グランドプリンスホテル京都）
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-26462011
[Presentation] 潰瘍性大腸炎癌化におけるmicroRNA-124、-137、-34b/cメチル化の意義
- Author(s)
  問山裕二, Hur Keun, 沖上正人, 川村幹雄, 川本文, 奥川喜永, 廣純一郎, 荒木俊光, 田中光司, 井上靖浩, 内田恵一, 毛利靖彦, 楠正人, Boland Richard C., Goel Ajay
- Organizer
  日本癌治療学会
- Place of Presentation
  横浜　（パシフィコ横浜）
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-26462011

1. Toiyama Yuji (00422824)

# of Collaborated Projects: 8 results

# of Collaborated Products: 15 results
2. 奥川喜永 (30555545)

# of Collaborated Projects: 7 results

# of Collaborated Products: 10 results
3. 大北喜基 (20378342)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
4. 楠正人 (50192026)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. 大井正貴 (40418752)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. 今岡裕基 (70762938)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
7. 北嶋貴仁 (30586772)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. FUJIKAWA HIROYUKI (40616091)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YAMAMOTO Akira (10889322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 吉山繁幸 (60444436)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KONDO SATORU (60763737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. HIRO JYUNICHIRO (70444437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 井上靖浩 (20324535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 荒木俊光 (70343217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 安田裕美 (60586767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 橋本清 (20939988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 志村匡信 (90734575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 森本雄貴 (30586764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kawamura Mikio 川村 幹雄

Research Projects

Research Products

Co-Researchers

放射線照射とDNA修復機能抑制性ウイルスベクター導入による直腸癌免疫賦活療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and validation of a versatile panel targeting colorectal cancer-specific circulating methylated DNA through comprehensive analysis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neutrophil extracellular traps（NETs）を介した食道癌進展の新たな機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

AIとradiomicsによる直腸癌術前治療の効果予測プログラム開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of RNA methylation biomarker in Colorectal Cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a minimally invasive ulcerative colitis cancer risk diagnostic method using integrated genomic and epigenomic analysis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A Molecular Biological Approach to the Diagnosis and Treatment Planning for Ulcerative Colitis-associated Cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanistic exploration of epigenetic change as for organ specific metastasis in gastric cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analyses of DNA methylation for the development of pouchitis after surgery in patients with ulcerative colitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA methylation biomarkers predict development of UC-associated colorectal neoplasia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Double inferior vena cava, an uncommon but relevant anatomical anomaly in surgery for lower rectal cancer: a report of two cases2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Promoter methylation levels of microRNA-124 in non-neoplastic rectal mucosa as a potential biomarker for ulcerative colitis-associated colorectal cancer in pediatric-onset patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 潰瘍性大腸炎関連癌の分子生物学的アプローチを用いた診断法2022

Author(s)

Journal Title

Data Source

[Journal Article] A Molecular Biological Approach to the Diagnosis of Ulcerative Colitis-associated Cancer2022

Author(s)

Kawamura Mikio 川村幹雄

[Presentation] IBD合併癌(Colitic Cancer)のサーベイランスと治療定量的メチル化解析による潰瘍性大腸炎癌化危険群推定の可能性