Shibata Takehiko 柴田岳彦

Researcher Number	00739196
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京医科大学, 医学部, 准教授 2018 – 2019: 国立感染症研究所, 免疫部, 主任研究官 2016 – 2017: 国立感染症研究所, 免疫部, 研究員 2014 – 2015: 国立感染症研究所, その他部局等, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Immunology Except Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator アレルギー / 感染症 / Gas6 / Axl / RSV / ワクチン / RSウイルス / Gas6/Axl / 免疫制御 / 糖尿病 … More / 老化 / 細胞老化 / 加齢 / 重症化 / マクロファージ / 気管支喘息 / 好中球 / M2様マクロファージ / MMP-12 / 増悪 / 喘息 / アレルギー・ぜんそく / ウィルス / 免疫学 / タイプ2免疫 / Th1/Th2 / 衛生仮説 Less

RSウイルス感染に伴うMMP-12産生とCOPD増悪機構の解明
- Principal Investigator
  
  中野千裕
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Toho University
Regulation of immune response by aging-induced Gas6/Axl axis.Principal Investigator
- Principal Investigator
  
  Shibata Takehiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo Medical University
The mechanism of RSV-induced exacerbation of asthmaPrincipal Investigator
- Principal Investigator
  
  Shibata Takehiko
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo Medical University
  National Institute of Infectious Diseases
The role of Gas6/Axl signal in the immune response associated with RSV infectionPrincipal Investigator
- Principal Investigator
  
  Shibata Takehiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  National Institute of Infectious Diseases
The effect of RSV infection in infancy on hygiene hypothesisPrincipal Investigator
- Principal Investigator
  
  Shibata Takehiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  National Institute of Infectious Diseases
RSV感染におけるGas6/TAMシグナリングによる免疫応答の制御機構の解明Principal Investigator
- Principal Investigator
  
  柴田岳彦
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  National Institute of Infectious Diseases

All 2024 2023 2021 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] A critical role of Gas6/Axl signal in allergic airway responses during RSV vaccine-enhanced disease2017
- Author(s)
  Shibata Takehiko、Ato Manabu
- Journal Title
  
  Immunology & Cell Biology
  
  Volume: 95 Issue: 10 Pages: 906-915
- DOI
  10.1038/icb.2017.61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06246
[Journal Article] Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.2014
- Author(s)
  Shibata T, Habiel DM, Coelho AL, Kunkel SL, Lukacs NW, Hogaboam CM.
- Journal Title
  
  Journal of Immunology
  
  Volume: 192 Issue: 8 Pages: 3569-3581
- DOI
  10.4049/jimmunol.1302766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893333
[Journal Article] Role of growth arrest-specific gene 6 in the development of fungal allergic airway disease in mice.2014
- Author(s)
  Shibata T, Ismailoglu UB, Kittan NA, Moreira AP, Coelho AL, Chupp GL, Kunkel SL, Lukacs NW, Hogaboam CM.
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 5 Issue: 5 Pages: 615-625
- DOI
  10.1165/rcmb.2014-0049oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893333
[Journal Article] Axl receptor blockade protects from invasive pulmonary aspergillosis in mice.2014
- Author(s)
  Shibata T, Habiel DM, Coelho AL, Hogaboam CM.
- Journal Title
  
  Journal of Immunology
  
  Volume: 193 Issue: 7 Pages: 3559-3565
- DOI
  10.4049/jimmunol.1401258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893333
[Journal Article] Gas6'ing the innate immune response during experimental asthma.2014
- Author(s)
  Shibata T, Hogaboam CM.
- Journal Title
  
  Annals of the American Thoracic Society
  
  Volume: Suppl 5 Issue: Supplement 5 Pages: S303-S305
- DOI
  10.1513/annalsats.201401-013aw
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893333
[Presentation] High levels of Gas6 induced by cellular senescence in aged mice cause severe infections2024
- Author(s)
  呉優貴恵、柴田岳彦
- Organizer
  第52回日本免疫学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02929
[Presentation] 呼吸器感染症の重症化とその回避2023
- Author(s)
  柴田岳彦
- Organizer
  大阪大学微生物病研究所 Advanced Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-21H02929
[Presentation] RSウイルス感染に伴うMMP-12産生と好中球浸潤の促進はアレルギー性気道炎症を増悪させる2021
- Author(s)
  柴田岳彦
- Organizer
  第95回日本感染症学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08618
[Presentation] RSウイルス感染が誘導するMMP-12はアレルギー性気道炎症を増悪させる2021
- Author(s)
  柴田岳彦
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08618
[Presentation] Increased matrix metalloproteinase-12 by respiratory syncytial virus infection leads to the exacerbation of asthma2019
- Author(s)
  Airi Makino, Kisaburo Nagata, Toshihiro Ito, Yoshimasa Takahashi, Takehiko Shibata
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K08618
[Presentation] RSV induces suppressive Gas6/Axl signaling in macrophages increasing susceptibility to secondary S. pneumoniae infection.2018
- Author(s)
  Takehiko Shibata, Toshihiro Ito, Yoshimasa Takahashi, Manabu Ato
- Organizer
  The 47th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-16H06246
[Presentation] The role of RSV-induced Gas6/Axl signaling in secondary bacterial infection.2017
- Author(s)
  Takehiko Shibata
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06246
[Presentation] RSV-induced Gas6/Axl signal ultimately leads to severer bacterial pneumonia2017
- Author(s)
  Takehiko Shibata
- Organizer
  the 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06246
[Presentation] Gas6/Axl signal causes the failure of RSV vaccine development in mice.2016
- Author(s)
  Takehiko Shibata, Manabu Ato
- Organizer
  The 24th International Symposium on Molecular Cell Biology of Macrophages
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06246
[Presentation] Gas6/Axl signal plays critical roles in allergic responses and insufficient protection by formalin-inactivated RSV vaccine in mice2016
- Author(s)
  Takehiko Shibata, Manabu Ato
- Organizer
  第45回日本免疫学会学術集会46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06246
[Presentation] Gas6/TAMシグナリングによる免疫応答の制御2015
- Author(s)
  柴田岳彦
- Organizer
  第24回東京免疫フォーラム
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2015-02-25
- Data Source
  KAKENHI-PROJECT-26893333
[Presentation] A Role of Gas6/TAM signaling in the development and exacerbation of fungal allergic airway disease in mice
- Author(s)
  Takehiko Shibata
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26893333

1. 中野千裕 (60769933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 小高倫生 (30385710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松瀬厚人 (60336154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shibata Takehiko 柴田 岳彦

Research Projects

Research Products

Co-Researchers

RSウイルス感染に伴うMMP-12産生とCOPD増悪機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of immune response by aging-induced Gas6/Axl axis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of RSV-induced exacerbation of asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of Gas6/Axl signal in the immune response associated with RSV infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of RSV infection in infancy on hygiene hypothesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RSV感染におけるGas6/TAMシグナリングによる免疫応答の制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A critical role of Gas6/Axl signal in allergic airway responses during RSV vaccine-enhanced disease2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of growth arrest-specific gene 6 in the development of fungal allergic airway disease in mice.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Axl receptor blockade protects from invasive pulmonary aspergillosis in mice.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gas6'ing the innate immune response during experimental asthma.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] High levels of Gas6 induced by cellular senescence in aged mice cause severe infections2024

Author(s)

Organizer

Data Source

[Presentation] 呼吸器感染症の重症化とその回避2023

Author(s)

Organizer

Data Source

[Presentation] RSウイルス感染に伴うMMP-12産生と好中球浸潤の促進は アレルギー性気道炎症を増悪させる2021

Author(s)

Organizer

Data Source

[Presentation] RSウイルス感染が誘導するMMP-12はアレルギー性気道炎症を増悪させる2021

Author(s)

Organizer

Shibata Takehiko 柴田岳彦

[Presentation] RSウイルス感染に伴うMMP-12産生と好中球浸潤の促進はアレルギー性気道炎症を増悪させる2021