IKUTA Takahisa 生田貴久

Researcher Number	00746563
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2023: 徳島大学, 大学院医歯薬学研究部(歯学域), 助教 2016 – 2018: 徳島大学, 病院, 医員 2015: 徳島大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontology Except Principal Investigator Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator 糖尿病関連歯周炎 / AGEs / 歯周病原細菌 / エキソソーム / 歯肉上皮細胞 / 歯根膜線維芽細胞 / サイトカイン / 炎症反応 / 歯周医学 / 高グルコース … More / エクソソーム / 糖尿病性歯周炎 / リポカリン２ / 低酸素環境 / LPS / 最終糖化産物 / ヒト歯肉線維芽細胞 / ヒト歯肉繊維芽細胞 / sIL-6R / THP-1 / IL-6 / TLR4 / カルプロテクチン … More Except Principal Investigator 骨細胞 / AGEs / 歯肉溝滲出液 / スクレロスチン / 糖尿病関連歯周炎 / 推算糸球体濾過量 / 血清抗体価 / 歯周病原細菌 / ペリオドンタルメディシン / 慢性腎臓病 / 歯周病 Less

Development of a non-invasive diagnostic method for diabetes-related periodontitis using sclerostin as a novel target bio-marker
- Principal Investigator
  
  INAGAKI Yuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Study of exosomes from cells in periodontal tissues with diabetes-associated periodontitisPrincipal Investigator
- Principal Investigator
  
  IKUTA Takahisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Relationship between periodontal pathogen and estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease
- Principal Investigator
  
  二宮雅美
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Study of effects of advanced glycation end-products and LPS under hypoxia on the pathological condition of diabetes-associated periodontitisPrincipal Investigator
- Principal Investigator
  
  IKUTA Takahisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
The effect of calprotectin on mechanism of progression of diabetes-associated periodontitisPrincipal Investigator
- Principal Investigator
  
  IKUTA Takahisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima

All 2023 2021 2020 2019 2017 2015

All Journal Article Presentation

[Journal Article] Advanced glycation end‐products increase lipocalin 2 expression in human oral epithelial cells2020
- Author(s)
  Kido Rie、Hiroshima Yuka、Kido Jun‐ichi、Ikuta Takahisa、Sakamoto Eijiro、Inagaki Yuji、Naruishi Koji、Yumoto Hiromichi
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: - Issue: 4 Pages: 539-550
- DOI
  10.1111/jre.12741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17352, KAKENHI-PROJECT-18K17051, KAKENHI-PROJECT-17H04418
[Journal Article] Advanced glycation end-products increase IL-6 and ICAM-1 expression via RAGE, MAPK and NF-κB pathways in human gingival fibroblasts2017
- Author(s)
  Nonaka K.、Kajiura Y.、Bando M.、Sakamoto E.、Inagaki Y.、Lew J. H.、Naruishi K.、Ikuta T.、Yoshida K.、Kobayashi T.、Yoshie H.、Nagata T.、Kido J.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: - Issue: 3 Pages: 1-11
- DOI
  10.1111/jre.12518
- NAID
  120006845647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11391, KAKENHI-PROJECT-15K20621
[Journal Article] Clinical significance of GCF sIL-6R and calprotectin to evaluate the periodontal inflammation.2017
- Author(s)
  Kajiura Y, Lew JH, Ikuta T, Nishikawa Y, Kido J, Nagata T, Naruishi K. ANNALS EXPRESS
- Journal Title
  
  Annals of Clinical Biochemistry
  
  Volume: 印刷中 Issue: 6 Pages: 1-7
- DOI
  10.1177/0004563216680232
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253104, KAKENHI-PROJECT-16K20673, KAKENHI-PROJECT-15H05054, KAKENHI-PROJECT-15K20621
[Presentation] 休眠状態の脂肪組織由来間葉系幹細胞による細胞老化随伴分泌現象の解除と糖尿病性合併症治療への応用の可能性2023
- Author(s)
  船木真理，秦明子，吉田光輝，宮本直輝，生田貴久，植村勇太，秋月皆人，丹黒章，湯本浩通，小川博久，尾矢剛志
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K09895
[Presentation] Quiescence Recovers Adipose Tissue-Derived Stromal Cells from Senescence-Associated Secretory Phenotype, Leading to Enhanced Angiogenesis and Diabetic Wound Healing2023
- Author(s)
  Makoto Funaki, Akiko Hata, Mitsuteru Yoshida, Naoki Miyamoto, Takahisa Ikuta, Yuta Uemura, Minato Akizuki, Akira Tangoku, Hiromichi Yumoto, Hirohisa Ogawa, Takeshi Oya
- Organizer
  83nd Scientific Sessions presented by the American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09895
[Presentation] PCRを用いたTreponema denticola, Tannerella forsythia迅速検出システムの有用性2023
- Author(s)
  二宮雅美、生田貴久、秋月皆人、植村勇太、湯本浩通
- Organizer
  日本歯科保存学会2023年度春季学術大会（第158回）
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] 人工合成したSecretory leukocyte protease inhibitorの抗菌活性とリポソーム封入2023
- Author(s)
  木戸理恵，廣島佑香，木戸淳一，吉田賀弥，生田貴久，湯本浩通
- Organizer
  第66回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09895
[Presentation] 感冒後に重篤化した壊死性潰瘍性歯肉炎の一症例2021
- Author(s)
  二宮雅美、植村勇太、秋月皆人、生田貴久、湯本浩通
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] チェアサイドでのPorphyromonas gingivalis迅速検出システムの有用性2021
- Author(s)
  秋月皆人、二宮雅美、植村勇太、生田貴久、成石浩司、湯本浩通
- Organizer
  四国歯学会第57回例会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] PCRを用いたPorphyromonas gingivalis2型線毛迅速検出システムの有効性の検討2021
- Author(s)
  生田貴久、二宮雅美、秋月皆人、植村勇太、成石浩司、湯本浩通
- Organizer
  第64回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] PCRを用いたPorphyromonas gingivalis迅速検出システムの有用性2020
- Author(s)
  秋月皆人、二宮雅美、植村勇太、生田貴久、成石浩司、湯本浩通
- Organizer
  日本歯科保存学会第153回2020年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] 最終糖化産物による口腔上皮細胞の Lipocalin2 発現誘導は好中球の遊走性とサイトカイン発現を調節する2020
- Author(s)
  木戸理恵, 廣島佑香, 生田貴久, 稲垣裕司, 板東美香, 成石浩司, 木戸淳一, 湯本浩通
- Organizer
  第63回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K17051
[Presentation] 歯周病ならびに歯周組織再生療法に関する臨床研究について2020
- Author(s)
  植村勇太、二宮雅美、和田明大、木戸理恵、高木亮輔、野中康平、谷口裕哉、生田貴久、坂本英次郎、板東美香、稲垣裕司、成石浩司、木戸淳一、湯本浩通
- Organizer
  徳島県歯科医学大会・四国歯学会第56回例会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] 下顎第一大臼歯の重度骨欠損に対してリグロスとサイトランスグラニュールを併用した歯周組織再生療法を行った一症例2020
- Author(s)
  二宮雅美、植村勇太、和田明大、生田貴久、湯本浩通
- Organizer
  第63回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] 最終糖化産物はヒト口腔上皮細胞のリポカリン２発現を増加する2019
- Author(s)
  木戸理恵，廣島佑香，生田貴久，吉田賀弥，稲垣裕司，成石浩司，尾崎和美，木戸淳一，湯本浩通
- Organizer
  第62回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K17051
[Presentation] 重度慢性歯周炎を有する血液透析患者に対して包括的歯周治療を行った一症例2019
- Author(s)
  二宮雅美、生田貴久、成石浩司、湯本浩通
- Organizer
  日本歯科保存学会2019年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] 周期性好中球減少症を有する母娘に認められた重度歯周炎の症例2019
- Author(s)
  二宮雅美、坂本英次郎、成石浩司、生田貴久、高木亮輔、畑中加珠、岡本憲太郎、小野晋太郎、高柴正悟, 湯本浩通
- Organizer
  第62回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10111
[Presentation] ヒト口腔上皮細胞と歯肉線維芽細胞において低酸素環境が誘導する遺伝子発現の比較2015
- Author(s)
  木戸淳一、板東美香、中島由紀子、梶浦由加里、稲垣裕司、生田貴久、坂本英次郎、成石浩司、永田俊彦
- Organizer
  第143回秋季日本歯科保存学会
- Place of Presentation
  文京ビックホール(東京都文京区）)
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K20621
[Presentation] 最終糖化産物は口腔上皮細胞の遺伝子発現を調節する2015
- Author(s)
  坂本英次郎、木戸淳一、梶浦由加里、板東美香、稲垣裕司、成石浩司、生田貴久、永田俊彦
- Organizer
  第58回秋季日本歯周病学会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K20621
[Presentation] YKL-40 in gingival crevicular fliuid from patients with periodontitis and diabetes.2015
- Author(s)
  Ikuta T, Kajiura Y, Bando Y, Bando M, Inagaki Y, Naruishi K, Kido J, Nagata T.
- Organizer
  Euro Perio 2015
- Place of Presentation
  London UK
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-15K20621

1. INAGAKI Yuji (50380019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 湯本浩通 (60284303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. 木戸淳一 (10195315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 二宮雅美 (10291494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 板東美香 (10510000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 廣島佑香 (60545143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 木戸理恵 (60876027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. NARUISHI Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 二宮政美

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
10. 永田俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IKUTA Takahisa 生田 貴久

Research Projects

Research Products

Co-Researchers

Development of a non-invasive diagnostic method for diabetes-related periodontitis using sclerostin as a novel target bio-marker

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of exosomes from cells in periodontal tissues with diabetes-associated periodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Relationship between periodontal pathogen and estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of effects of advanced glycation end-products and LPS under hypoxia on the pathological condition of diabetes-associated periodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of calprotectin on mechanism of progression of diabetes-associated periodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Advanced glycation end‐products increase lipocalin 2 expression in human oral epithelial cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Advanced glycation end-products increase IL-6 and ICAM-1 expression via RAGE, MAPK and NF-κB pathways in human gingival fibroblasts2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Clinical significance of GCF sIL-6R and calprotectin to evaluate the periodontal inflammation.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 休眠状態の脂肪組織由来間葉系幹細胞による細胞老化随伴分泌現象の解除と糖尿病性合併症治療への応用の可能性2023

Author(s)

Organizer

Data Source

[Presentation] Quiescence Recovers Adipose Tissue-Derived Stromal Cells from Senescence-Associated Secretory Phenotype, Leading to Enhanced Angiogenesis and Diabetic Wound Healing2023

Author(s)

Organizer

Data Source

[Presentation] PCRを用いたTreponema denticola, Tannerella forsythia迅速検出システムの有用性2023

Author(s)

Organizer

Data Source

[Presentation] 人工合成したSecretory leukocyte protease inhibitorの抗菌活性とリポソーム封入2023

Author(s)

Organizer

Data Source

[Presentation] 感冒後に重篤化した壊死性潰瘍性歯肉炎の一症例2021

Author(s)

Organizer

Data Source

[Presentation] チェアサイドでのPorphyromonas gingivalis迅速検出システムの有用性2021

Author(s)

Organizer

Data Source

[Presentation] PCRを用いたPorphyromonas gingivalis2型線毛迅速検出システムの有効性の検討2021

Author(s)

Organizer

Data Source

[Presentation] PCRを用いたPorphyromonas gingivalis迅速検出システムの有用性2020

Author(s)

IKUTA Takahisa 生田貴久